CDHR3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.94327181
2left/right axis specification (GO:0070986)9.67978717
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.78549386
4GTP biosynthetic process (GO:0006183)8.34020684
5motile cilium assembly (GO:0044458)8.09639134
6UTP biosynthetic process (GO:0006228)7.45509676
7primary alcohol catabolic process (GO:0034310)7.17911088
8UTP metabolic process (GO:0046051)7.08987084
9C21-steroid hormone biosynthetic process (GO:0006700)7.08688519
10progesterone metabolic process (GO:0042448)7.02326573
11nucleoside diphosphate phosphorylation (GO:0006165)6.88698426
12intraciliary transport (GO:0042073)6.65183878
13vitamin transmembrane transport (GO:0035461)6.64182188
14ethanol metabolic process (GO:0006067)5.99695411
15microtubule bundle formation (GO:0001578)5.99324369
16cilium organization (GO:0044782)5.62079144
17diterpenoid biosynthetic process (GO:0016102)5.61377086
18response to xenobiotic stimulus (GO:0009410)5.47189870
19guanosine-containing compound biosynthetic process (GO:1901070)5.32521014
20cilium morphogenesis (GO:0060271)5.32514031
21CTP biosynthetic process (GO:0006241)5.30843758
22CTP metabolic process (GO:0046036)5.30843758
23cilium assembly (GO:0042384)5.24829954
24regulation of microtubule-based movement (GO:0060632)5.17553739
25pyrimidine-containing compound transmembrane transport (GO:0072531)5.02120057
26tolerance induction (GO:0002507)4.96595730
27pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.86147480
28centriole assembly (GO:0098534)4.82668976
29pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.74965674
30regulation of interleukin-5 production (GO:0032674)4.72373202
31lateral ventricle development (GO:0021670)4.72256441
32negative regulation of T cell differentiation in thymus (GO:0033085)4.51087534
33negative regulation of immunoglobulin mediated immune response (GO:0002890)4.47983687
34ethanol oxidation (GO:0006069)4.35794093
35cellular component assembly involved in morphogenesis (GO:0010927)4.28122171
36microtubule-based movement (GO:0007018)4.26289844
37C21-steroid hormone metabolic process (GO:0008207)4.20500842
38regulation of interleukin-13 production (GO:0032656)4.18588308
39embryonic retina morphogenesis in camera-type eye (GO:0060059)4.16057464
40one-carbon compound transport (GO:0019755)4.12806705
41sperm capacitation (GO:0048240)4.12796465
42regulation of germinal center formation (GO:0002634)4.05713866
43terpenoid biosynthetic process (GO:0016114)3.95691662
44negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.91621448
45nucleotide phosphorylation (GO:0046939)3.90191497
46microtubule severing (GO:0051013)3.88709460
47retinoic acid metabolic process (GO:0042573)3.88061293
48establishment or maintenance of monopolar cell polarity (GO:0061339)3.87068069
49establishment of monopolar cell polarity (GO:0061162)3.87068069
50surfactant homeostasis (GO:0043129)3.86882915
51positive regulation of tolerance induction (GO:0002645)3.84680697
52establishment of nucleus localization (GO:0040023)3.83170022
53cytoplasmic microtubule organization (GO:0031122)3.81888850
54cell projection assembly (GO:0030031)3.71249317
55glomerular epithelial cell development (GO:0072310)3.69407943
56exogenous drug catabolic process (GO:0042738)3.61485160
57pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.60800103
58microtubule depolymerization (GO:0007019)3.55272760
59microtubule polymerization or depolymerization (GO:0031109)3.46968222
60regulation of macrophage chemotaxis (GO:0010758)3.46080747
61regulation of pigment cell differentiation (GO:0050932)3.37797202
62protein localization to cilium (GO:0061512)3.36266939
63establishment of tissue polarity (GO:0007164)3.31212719
64establishment of planar polarity (GO:0001736)3.31212719
65retinal rod cell development (GO:0046548)3.29588928
66pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.22991713
67nonmotile primary cilium assembly (GO:0035058)3.22437420
68pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.21139789
69primary alcohol metabolic process (GO:0034308)3.19100514
70O-glycan processing (GO:0016266)3.18252557
71positive regulation of smoothened signaling pathway (GO:0045880)3.14656257
72regulation of glucose import in response to insulin stimulus (GO:2001273)3.13752802
73gas transport (GO:0015669)3.13545903
74glutathione derivative metabolic process (GO:1901685)3.13032690
75glutathione derivative biosynthetic process (GO:1901687)3.13032690
76nucleoside diphosphate metabolic process (GO:0009132)3.11924777
77pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.10672832
78chemical homeostasis within a tissue (GO:0048875)3.04716138
79retinol metabolic process (GO:0042572)3.04359606
80detection of calcium ion (GO:0005513)3.02166659
81regulation of cilium movement (GO:0003352)2.99490921
82cardiovascular system development (GO:0072358)2.98975559
83pyrimidine ribonucleotide metabolic process (GO:0009218)2.97031721
84lateral sprouting from an epithelium (GO:0060601)2.96391842
85aldehyde catabolic process (GO:0046185)2.95504809
86smoothened signaling pathway (GO:0007224)2.94810353
87microtubule-based process (GO:0007017)2.89587859
88hydrogen peroxide biosynthetic process (GO:0050665)2.88534759
89regulation of mononuclear cell migration (GO:0071675)2.87473763
90drug catabolic process (GO:0042737)2.86620723
91ketone biosynthetic process (GO:0042181)2.86425023
92positive regulation of protein depolymerization (GO:1901881)2.86198659
93sperm motility (GO:0030317)2.86176282
94left/right pattern formation (GO:0060972)2.85773561
95regulation of microtubule depolymerization (GO:0031114)2.84225790
96regulation of tolerance induction (GO:0002643)2.83385388
97positive regulation of protein kinase C signaling (GO:0090037)2.81824665
98oxygen transport (GO:0015671)2.78388363
99carnitine metabolic process (GO:0009437)2.77796643
100apical protein localization (GO:0045176)2.77787606
101regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.73894974
102retinal cone cell development (GO:0046549)2.71156710
103centriole replication (GO:0007099)2.69732860
104determination of left/right symmetry (GO:0007368)2.68810277
105embryonic camera-type eye development (GO:0031076)2.68520032
106phosphatidylcholine biosynthetic process (GO:0006656)2.65773730
107organelle assembly (GO:0070925)2.65634719
108phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.65289400
109regulation of protein polyubiquitination (GO:1902914)2.64379768
110determination of bilateral symmetry (GO:0009855)2.60162678
111S-adenosylmethionine metabolic process (GO:0046500)2.57456639
112specification of symmetry (GO:0009799)2.57216368
113regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.57134937
114photoreceptor cell maintenance (GO:0045494)2.56106744
115multicellular organismal water homeostasis (GO:0050891)2.56103928
116regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.55645680
117reactive oxygen species biosynthetic process (GO:1903409)2.54743311
118calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.53668303
119pyrimidine ribonucleoside metabolic process (GO:0046131)2.53133166
120nonribosomal peptide biosynthetic process (GO:0019184)2.52258820
121excretion (GO:0007588)2.50439087
122iron ion import (GO:0097286)2.50122764
123heart looping (GO:0001947)2.48573675
124negative regulation of inclusion body assembly (GO:0090084)2.48543206
125peptide hormone processing (GO:0016486)2.45878186
126positive regulation of cellular response to insulin stimulus (GO:1900078)2.45679927
127dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.43442149
128camera-type eye morphogenesis (GO:0048593)2.42859825
129lung epithelium development (GO:0060428)2.41561877
130multicellular organismal aging (GO:0010259)2.40656780
131CDP-diacylglycerol biosynthetic process (GO:0016024)2.39970649
132nucleus localization (GO:0051647)2.39935233
133brain morphogenesis (GO:0048854)2.39854859
134hydrogen peroxide catabolic process (GO:0042744)2.38986687
135glomerular visceral epithelial cell development (GO:0072015)2.38133465
136sodium ion homeostasis (GO:0055078)2.38088556
137establishment or maintenance of apical/basal cell polarity (GO:0035088)2.37687736
138establishment or maintenance of bipolar cell polarity (GO:0061245)2.37687736
139hypotonic response (GO:0006971)2.37220072
140axon ensheathment in central nervous system (GO:0032291)2.36281225
141central nervous system myelination (GO:0022010)2.36281225
142purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.36275032
143photoreceptor cell differentiation (GO:0046530)2.35598008
144eye photoreceptor cell differentiation (GO:0001754)2.35598008
145carnitine transmembrane transport (GO:1902603)2.35055768
146negative regulation of humoral immune response (GO:0002921)2.34945843
147regulation of autophagic vacuole assembly (GO:2000785)2.34435711
148establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.33862676
149negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902176)2.33787379
150glycine transport (GO:0015816)2.29351252
151purine nucleoside triphosphate biosynthetic process (GO:0009145)2.29161010
152ADP metabolic process (GO:0046031)2.28339884
153lymphangiogenesis (GO:0001946)2.26947276
154positive regulation of striated muscle cell differentiation (GO:0051155)2.23004270
155monocyte differentiation (GO:0030224)2.19777363
156establishment of apical/basal cell polarity (GO:0035089)2.17633417
157developmental induction (GO:0031128)2.15167237
158substrate-independent telencephalic tangential migration (GO:0021826)2.13034180
159substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.13034180
160keratinocyte development (GO:0003334)2.11356891
161negative regulation of B cell mediated immunity (GO:0002713)2.11017199
162cilium movement (GO:0003341)15.4520497
163axonemal dynein complex assembly (GO:0070286)15.2391657
164cilium or flagellum-dependent cell motility (GO:0001539)11.8794939
165ventricular system development (GO:0021591)10.5952965
166axoneme assembly (GO:0035082)10.4739745

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.89499025
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.33696525
3FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.52883517
4AR_21572438_ChIP-Seq_LNCaP_Human3.34783654
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.15996234
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.88222672
7CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.78068683
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.57600575
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.31249340
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.30929350
11ESR1_20079471_ChIP-ChIP_T-47D_Human2.24730402
12VDR_22108803_ChIP-Seq_LS180_Human2.23767869
13DROSHA_22980978_ChIP-Seq_HELA_Human2.04572006
14IGF1R_20145208_ChIP-Seq_DFB_Human2.00589960
15EZH2_27294783_Chip-Seq_ESCs_Mouse1.88263215
16SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.85154843
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.83120356
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.81346899
19ESR1_21235772_ChIP-Seq_MCF-7_Human1.79838685
20* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.74614042
21PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.71505314
22TP63_23658742_ChIP-Seq_EP156T_Human1.70111730
23AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.70066230
24SOX2_27498859_Chip-Seq_STOMACH_Mouse1.65345272
25ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.64755638
26RUNX1_27514584_Chip-Seq_MCF-7_Human1.63895051
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.63760762
28SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.60899683
29STAT1_20625510_ChIP-Seq_HELA_Human1.58439269
30SMAD4_21799915_ChIP-Seq_A2780_Human1.57139963
31GBX2_23144817_ChIP-Seq_PC3_Human1.56247379
32ESR2_21235772_ChIP-Seq_MCF-7_Human1.56177925
33SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.54174760
34SMC4_20622854_ChIP-Seq_HELA_Human1.52667518
35CTNNB1_20460455_ChIP-Seq_HCT116_Human1.52297768
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.51084115
37EZH2_18974828_ChIP-Seq_MESCs_Mouse1.51084115
38MTF2_20144788_ChIP-Seq_MESCs_Mouse1.49516443
39SUZ12_27294783_Chip-Seq_ESCs_Mouse1.48776180
40ETV1_20927104_ChIP-Seq_GIST48_Human1.47904416
41ARNT_22903824_ChIP-Seq_MCF-7_Human1.47755411
42KLF5_25053715_ChIP-Seq_YYC3_Human1.43854771
43FOXA1_25552417_ChIP-Seq_VCAP_Human1.43093329
44JARID2_20064375_ChIP-Seq_MESCs_Mouse1.40773409
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.40646774
46PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.40101992
47LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39698321
48TDRD3_21172665_ChIP-Seq_MCF-7_Human1.39440420
49CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.38111419
50* PIAS1_25552417_ChIP-Seq_VCAP_Human1.38015945
51TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37112173
52STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36385900
53AHR_22903824_ChIP-Seq_MCF-7_Human1.36202917
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.34508536
55STAT3_23295773_ChIP-Seq_U87_Human1.33778491
56PHF8_20622853_ChIP-Seq_HELA_Human1.32877543
57JARID2_20075857_ChIP-Seq_MESCs_Mouse1.30943723
58TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30903705
59BCAT_22108803_ChIP-Seq_LS180_Human1.30672982
60EED_16625203_ChIP-ChIP_MESCs_Mouse1.30223882
61P63_26484246_Chip-Seq_KERATINOCYTES_Human1.30090934
62CDX2_20551321_ChIP-Seq_CACO-2_Human1.29777786
63* SMRT_27268052_Chip-Seq_Bcells_Human1.29770328
64RAD21_21589869_ChIP-Seq_MESCs_Mouse1.29723644
65* TP63_22573176_ChIP-Seq_HFKS_Human1.29501172
66SOX2_20726797_ChIP-Seq_SW620_Human1.29471440
67CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.29130985
68HNFA_21074721_ChIP-Seq_CACO-2_Human1.28774001
69* LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.28423545
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.28320224
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.27567507
72MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.26037502
73SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25798877
74STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.24787883
75CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22775752
76WT1_19549856_ChIP-ChIP_CCG9911_Human1.22468628
77ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21908475
78CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21236407
79AUTS2_25519132_ChIP-Seq_293T-REX_Human1.20780010
80RXR_22108803_ChIP-Seq_LS180_Human1.19751164
81RBPJ_21746931_ChIP-Seq_IB4_Human1.19519618
82EZH2_27304074_Chip-Seq_ESCs_Mouse1.19278480
83GATA4_25053715_ChIP-Seq_YYC3_Human1.18751862
84CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.18550598
85ERG_21242973_ChIP-ChIP_JURKAT_Human1.18342337
86* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17650989
87SMAD3_21741376_ChIP-Seq_HESCs_Human1.17551591
88FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16518442
89FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.16513780
90P300_19829295_ChIP-Seq_ESCs_Human1.16500469
91ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15567993
92FOXA2_19822575_ChIP-Seq_HepG2_Human1.15091461
93SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.14807539
94SMAD3_21741376_ChIP-Seq_EPCs_Human1.14446704
95RARG_19884340_ChIP-ChIP_MEFs_Mouse1.14435203
96CBX2_22325352_ChIP-Seq_293T-Rex_Human1.14058564
97CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.13930708
98RNF2_27304074_Chip-Seq_NSC_Mouse1.13664071
99GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13218798
100TP53_16413492_ChIP-PET_HCT116_Human1.12850922
101FOXO3_23340844_ChIP-Seq_DLD1_Human1.12809946
102TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12619545
103NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12461876
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12461876
105NFYA_21822215_ChIP-Seq_K562_Human1.12085395
106TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11523943
107GATA1_26923725_Chip-Seq_HPCs_Mouse1.10737358
108RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10464714
109PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.10419687
110GATA1_19941826_ChIP-Seq_K562_Human1.10246280
111ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10231989
112SMAD4_21741376_ChIP-Seq_EPCs_Human1.08657051
113EZH2_22144423_ChIP-Seq_EOC_Human1.08245806
114FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.08233510
115TBL1_22424771_ChIP-Seq_293T_Human1.07042224
116NFYB_21822215_ChIP-Seq_K562_Human1.06323241
117KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06092190
118PPAR_26484153_Chip-Seq_NCI-H1993_Human1.05954090
119GATA6_21074721_ChIP-Seq_CACO-2_Human1.05824237
120RNF2_27304074_Chip-Seq_ESCs_Mouse1.05768280
121SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05277330
122CEBPB_22108803_ChIP-Seq_LS180_Human1.04752261
123EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04312205
124SMAD4_21741376_ChIP-Seq_HESCs_Human1.03876848
125* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03859617
126E2F1_18555785_Chip-Seq_ESCs_Mouse1.03252255
127ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.03170364
128GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02734514
129FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02341818
130GATA3_24758297_ChIP-Seq_MCF-7_Human1.01875041
131STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.00213033
132TAL1_26923725_Chip-Seq_HPCs_Mouse0.99791757
133ELF1_20517297_ChIP-Seq_JURKAT_Human0.99518598
134TP53_18474530_ChIP-ChIP_U2OS_Human0.99022199
135RING1B_27294783_Chip-Seq_ESCs_Mouse0.99000081
136TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98496471
137AR_19668381_ChIP-Seq_PC3_Human0.97704533
138SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.97307667
139CTCF_20526341_ChIP-Seq_ESCs_Human0.96981753
140MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96606313
141CTCF_27219007_Chip-Seq_Bcells_Human0.94843113
142OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93996572
143BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.93941526
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93426627
145CBP_20019798_ChIP-Seq_JUKART_Human0.93426627
146CBX2_27304074_Chip-Seq_ESCs_Mouse0.93145265
147NANOG_18555785_Chip-Seq_ESCs_Mouse0.93060572
148WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92272851
149BMI1_23680149_ChIP-Seq_NPCS_Mouse0.91733091
150FLI1_27457419_Chip-Seq_LIVER_Mouse0.91170305
151GATA1_22025678_ChIP-Seq_K562_Human0.90309646
152PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.90181541
153TCF4_22108803_ChIP-Seq_LS180_Human0.89970921
154EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89838307
155SOX9_24532713_ChIP-Seq_HFSC_Mouse0.89339890
156SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88447496
157RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.88399256
158STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.88162337
159EP300_21415370_ChIP-Seq_HL-1_Mouse0.88136145
160CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88068037
161P53_22387025_ChIP-Seq_ESCs_Mouse0.88063967
162EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.87640435
163PHF8_20622854_ChIP-Seq_HELA_Human0.87177650
164EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.86015270
165AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85709261
166TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.85684311
167TCF4_23295773_ChIP-Seq_U87_Human0.83936292
168SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83672914

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008004_abnormal_stomach_pH9.40439597
2MP0003136_yellow_coat_color5.58005963
3MP0001984_abnormal_olfaction4.28087785
4MP0005623_abnormal_meninges_morphology4.18746112
5MP0004043_abnormal_pH_regulation4.01124511
6MP0004133_heterotaxia3.26784638
7MP0005647_abnormal_sex_gland3.09506798
8MP0002928_abnormal_bile_duct3.08904817
9MP0002653_abnormal_ependyma_morphology3.03558249
10MP0008789_abnormal_olfactory_epithelium3.00230037
11MP0004782_abnormal_surfactant_physiolog2.94087779
12MP0001958_emphysema2.78872019
13MP0000566_synostosis2.58371430
14MP0000383_abnormal_hair_follicle2.44809704
15MP0010368_abnormal_lymphatic_system2.43004366
16MP0001873_stomach_inflammation2.22444816
17MP0003878_abnormal_ear_physiology2.20744725
18MP0005377_hearing/vestibular/ear_phenot2.20744725
19MP0010678_abnormal_skin_adnexa2.09517540
20MP0009384_cardiac_valve_regurgitation2.06949133
21MP0002160_abnormal_reproductive_system2.03583972
22MP0004019_abnormal_vitamin_homeostasis1.97194878
23MP0003656_abnormal_erythrocyte_physiolo1.94659398
24MP0005499_abnormal_olfactory_system1.91248916
25MP0005394_taste/olfaction_phenotype1.91248916
26MP0005646_abnormal_pituitary_gland1.85191611
27MP0001440_abnormal_grooming_behavior1.82970159
28MP0002133_abnormal_respiratory_system1.77751134
29MP0005388_respiratory_system_phenotype1.77751134
30MP0001501_abnormal_sleep_pattern1.75094323
31MP0009780_abnormal_chondrocyte_physiolo1.73017690
32MP0008875_abnormal_xenobiotic_pharmacok1.67973141
33MP0003950_abnormal_plasma_membrane1.67659402
34MP0002736_abnormal_nociception_after1.67273594
35MP0001346_abnormal_lacrimal_gland1.63230384
36MP0001177_atelectasis1.62144367
37MP0004381_abnormal_hair_follicle1.59689748
38MP0000678_abnormal_parathyroid_gland1.56353593
39MP0005167_abnormal_blood-brain_barrier1.44636295
40MP0001879_abnormal_lymphatic_vessel1.43897568
41MP0001968_abnormal_touch/_nociception1.41548826
42MP0009046_muscle_twitch1.35944310
43MP0009379_abnormal_foot_pigmentation1.35538523
44MP0002282_abnormal_trachea_morphology1.33907229
45MP0000470_abnormal_stomach_morphology1.33727966
46MP0000613_abnormal_salivary_gland1.32751159
47MP0002168_other_aberrant_phenotype1.32590591
48MP0001663_abnormal_digestive_system1.27383471
49MP0005636_abnormal_mineral_homeostasis1.26412220
50MP0002132_abnormal_respiratory_system1.23151418
51MP0005248_abnormal_Harderian_gland1.22809974
52MP0004859_abnormal_synaptic_plasticity1.20763722
53MP0002249_abnormal_larynx_morphology1.20741287
54MP0003045_fibrosis1.18801193
55MP0001851_eye_inflammation1.18624690
56MP0002734_abnormal_mechanical_nocicepti1.15978634
57MP0005389_reproductive_system_phenotype1.12188774
58MP0001188_hyperpigmentation1.11814485
59MP0003690_abnormal_glial_cell1.07678558
60MP0005365_abnormal_bile_salt1.07534908
61MP0005381_digestive/alimentary_phenotyp1.06740901
62MP0003943_abnormal_hepatobiliary_system1.06569811
63MP0006054_spinal_hemorrhage1.06353404
64MP0002876_abnormal_thyroid_physiology1.05179823
65MP0002909_abnormal_adrenal_gland1.04818774
66MP0009745_abnormal_behavioral_response1.04473127
67MP0002295_abnormal_pulmonary_circulatio1.03720641
68MP0003724_increased_susceptibility_to1.03697719
69MP0002638_abnormal_pupillary_reflex1.00919651
70MP0010155_abnormal_intestine_physiology1.00354036
71MP0010234_abnormal_vibrissa_follicle0.99890181
72MP0003942_abnormal_urinary_system0.99435651
73MP0004883_abnormal_blood_vessel0.98474723
74MP0002233_abnormal_nose_morphology0.97175625
75MP0001502_abnormal_circadian_rhythm0.96832834
76MP0009643_abnormal_urine_homeostasis0.90135586
77MP0003635_abnormal_synaptic_transmissio0.89475978
78MP0005085_abnormal_gallbladder_physiolo0.89062622
79MP0000681_abnormal_thyroid_gland0.88616979
80MP0000465_gastrointestinal_hemorrhage0.88248294
81MP0005408_hypopigmentation0.88129002
82MP0002064_seizures0.87932278
83MP0003634_abnormal_glial_cell0.87737011
84MP0001485_abnormal_pinna_reflex0.87018602
85MP0005595_abnormal_vascular_smooth0.86832127
86MP0010030_abnormal_orbit_morphology0.86708158
87MP0002557_abnormal_social/conspecific_i0.83738947
88MP0002272_abnormal_nervous_system0.83687952
89MP0002136_abnormal_kidney_physiology0.82902711
90MP0005253_abnormal_eye_physiology0.82825134
91MP0003075_altered_response_to0.81784439
92MP0004885_abnormal_endolymph0.80139132
93MP0004484_altered_response_of0.79638984
94MP0005220_abnormal_exocrine_pancreas0.77565600
95MP0001849_ear_inflammation0.77143834
96MP0003698_abnormal_male_reproductive0.76789016
97MP0005551_abnormal_eye_electrophysiolog0.76304795
98MP0001929_abnormal_gametogenesis0.74703500
99MP0004264_abnormal_extraembryonic_tissu0.74599303
100MP0002139_abnormal_hepatobiliary_system0.73356167
101MP0004270_analgesia0.71910564
102MP0001270_distended_abdomen0.71270696
103MP0002277_abnormal_respiratory_mucosa0.70027300
104MP0000778_abnormal_nervous_system0.69579522
105MP0005083_abnormal_biliary_tract0.68014588
106MP0001765_abnormal_ion_homeostasis0.67637634
107MP0002572_abnormal_emotion/affect_behav0.67307490
108MP0004858_abnormal_nervous_system0.67209084
109MP0005310_abnormal_salivary_gland0.67060162
110MP0003633_abnormal_nervous_system0.65256005
111MP0005164_abnormal_response_to0.65203763
112MP0004272_abnormal_basement_membrane0.65088947
113MP0001943_abnormal_respiration0.64185848
114MP0001293_anophthalmia0.63796633
115MP0001324_abnormal_eye_pigmentation0.62866796
116MP0009765_abnormal_xenobiotic_induced0.62849175
117MP0005503_abnormal_tendon_morphology0.62443225
118MP0003937_abnormal_limbs/digits/tail_de0.61001855
119MP0003880_abnormal_central_pattern0.59168938
120MP0000026_abnormal_inner_ear0.59036847
121MP0003566_abnormal_cell_adhesion0.58016233
122MP0001299_abnormal_eye_distance/0.56896618
123MP0002098_abnormal_vibrissa_morphology0.56848778
124MP0002063_abnormal_learning/memory/cond0.56730918
125MP0002229_neurodegeneration0.56483397
126MP0001664_abnormal_digestion0.56145718
127MP0001756_abnormal_urination0.56061367
128MP0001905_abnormal_dopamine_level0.54791966
129MP0008874_decreased_physiological_sensi0.54692187
130MP0001486_abnormal_startle_reflex0.53205796
131MP0001970_abnormal_pain_threshold0.53059419
132MP0001944_abnormal_pancreas_morphology0.52755062
133MP0009703_decreased_birth_body0.52690116
134MP0005166_decreased_susceptibility_to0.52184994
135MP0002127_abnormal_cardiovascular_syste0.51717490
136MP0005195_abnormal_posterior_eye0.51358591
137MP0003890_abnormal_embryonic-extraembry0.51299226
138MP0002116_abnormal_craniofacial_bone0.50930337
139MP0005165_increased_susceptibility_to0.50782839
140MP0010329_abnormal_lipoprotein_level0.50629157
141MP0006082_CNS_inflammation0.50390023
142MP0005391_vision/eye_phenotype0.49739176
143MP0000049_abnormal_middle_ear0.49249205
144MP0005409_darkened_coat_color0.48598861
145MP0002405_respiratory_system_inflammati0.48234735
146MP0003303_peritoneal_inflammation0.47463538
147MP0009763_increased_sensitivity_to0.46894965
148MP0000467_abnormal_esophagus_morphology0.46582251
149MP0005395_other_phenotype0.46371472
150MP0002735_abnormal_chemical_nociception0.46318917
151MP0008872_abnormal_physiological_respon0.45775305
152MP0001175_abnormal_lung_morphology0.45095910
153MP0002234_abnormal_pharynx_morphology0.44897164
154MP0002135_abnormal_kidney_morphology0.44442944
155MP0002896_abnormal_bone_mineralization0.44335043
156MP0003122_maternal_imprinting0.44250777
157MP0001963_abnormal_hearing_physiology0.43411861
158MP0003195_calcinosis0.41755811
159MP0001666_abnormal_nutrient_absorption0.41512387
160MP0002084_abnormal_developmental_patter0.39413141
161MP0003938_abnormal_ear_development0.38663235

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.45389355
2Abnormal respiratory motile cilium morphology (HP:0005938)8.23395532
3Abnormal respiratory epithelium morphology (HP:0012253)8.23395532
4Chronic bronchitis (HP:0004469)7.32643271
5Dynein arm defect of respiratory motile cilia (HP:0012255)6.80058481
6Absent/shortened dynein arms (HP:0200106)6.80058481
7Bronchiectasis (HP:0002110)5.45708594
8Male infertility (HP:0003251)5.30843357
9Nasal polyposis (HP:0100582)5.09800190
10Abnormality of the nasal mucosa (HP:0000433)4.67590781
11Abnormal biliary tract physiology (HP:0012439)4.48479303
12Bile duct proliferation (HP:0001408)4.48479303
13True hermaphroditism (HP:0010459)4.31751283
14Occipital encephalocele (HP:0002085)4.22698493
15Pancreatic fibrosis (HP:0100732)4.13421208
16Tubulointerstitial nephritis (HP:0001970)4.00707647
17Abnormality of dentin (HP:0010299)3.59576022
18Bronchitis (HP:0012387)3.56058827
19Chronic sinusitis (HP:0011109)3.49798531
20Supernumerary spleens (HP:0009799)3.46145075
21Back pain (HP:0003418)3.42397831
22Infertility (HP:0000789)3.33226733
23Abnormality of the fetal cardiovascular system (HP:0010948)3.30432525
24Abnormal umbilical cord blood vessels (HP:0011403)3.30432525
25Single umbilical artery (HP:0001195)3.30432525
26Degeneration of the lateral corticospinal tracts (HP:0002314)3.29415174
27Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.29415174
28Cystic liver disease (HP:0006706)3.23088251
29Broad distal phalanx of finger (HP:0009836)3.15240973
30Pancreatic cysts (HP:0001737)3.12964221
31Asplenia (HP:0001746)3.11769758
32Chronic otitis media (HP:0000389)3.06072039
33Medial flaring of the eyebrow (HP:0010747)2.90927188
34Atelectasis (HP:0100750)2.83778145
35Recurrent sinusitis (HP:0011108)2.83412161
36Male pseudohermaphroditism (HP:0000037)2.83077394
37Aplasia/Hypoplasia of the spleen (HP:0010451)2.80923757
38Gait imbalance (HP:0002141)2.79477715
39Termporal pattern (HP:0011008)2.79388285
40Insidious onset (HP:0003587)2.79388285
41Congenital primary aphakia (HP:0007707)2.75187434
42Postaxial foot polydactyly (HP:0001830)2.64077480
43Genetic anticipation (HP:0003743)2.60928072
44Abnormality of the corticospinal tract (HP:0002492)2.47038531
45Nephrogenic diabetes insipidus (HP:0009806)2.45240180
46Abnormality of permanent molar morphology (HP:0011071)2.45004991
47Abnormality of the dental root (HP:0006486)2.45004991
48Taurodontia (HP:0000679)2.45004991
49Congenital hepatic fibrosis (HP:0002612)2.40894392
50Aplasia/Hypoplasia of the tongue (HP:0010295)2.37592734
51Abnormality of molar (HP:0011077)2.35827848
52Abnormality of molar morphology (HP:0011070)2.35827848
53Short nail (HP:0001799)2.28278418
54Recurrent otitis media (HP:0000403)2.27208522
55Recurrent bronchitis (HP:0002837)2.23511181
56Abnormality of the dental pulp (HP:0006479)2.19406936
57Tubulointerstitial abnormality (HP:0001969)2.17812400
58Anencephaly (HP:0002323)2.10435861
59Furrowed tongue (HP:0000221)2.04420776
60Agitation (HP:0000713)2.04096916
61Bell-shaped thorax (HP:0001591)2.03274628
62Chronic hepatic failure (HP:0100626)2.00023241
63Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.5228499
64Abnormal respiratory motile cilium physiology (HP:0012261)11.2934830
65Abnormal ciliary motility (HP:0012262)10.8353213
66Genital tract atresia (HP:0001827)1.98147206
67Abnormality of midbrain morphology (HP:0002418)1.97976571
68Molar tooth sign on MRI (HP:0002419)1.97976571
69Vaginal atresia (HP:0000148)1.95630437
70Nephronophthisis (HP:0000090)1.95171141
71Poor coordination (HP:0002370)1.91581590
72Abnormality of the umbilical cord (HP:0010881)1.90614155
73Tubular atrophy (HP:0000092)1.88913698
74Stage 5 chronic kidney disease (HP:0003774)1.88277682
75Oral leukoplakia (HP:0002745)1.87770747
76Median cleft lip (HP:0000161)1.87439125
77Breech presentation (HP:0001623)1.87170026
78Absent frontal sinuses (HP:0002688)1.85924956
79Hypotelorism (HP:0000601)1.85869136
80Natal tooth (HP:0000695)1.83708198
81Decreased circulating renin level (HP:0003351)1.77342005
82Sclerocornea (HP:0000647)1.74779487
83Absent rod-and cone-mediated responses on ERG (HP:0007688)1.72536102
84Preaxial hand polydactyly (HP:0001177)1.71925530
85Adrenal hypoplasia (HP:0000835)1.67877088
86Renal salt wasting (HP:0000127)1.67848586
87Oculomotor apraxia (HP:0000657)1.57794043
88Hyperkalemia (HP:0002153)1.57636406
89Rimmed vacuoles (HP:0003805)1.56325843
90Hemiplegia (HP:0002301)1.54201463
91Abnormality of the renal medulla (HP:0100957)1.52522745
92Urinary bladder sphincter dysfunction (HP:0002839)1.51222438
93Hyperactive renin-angiotensin system (HP:0000841)1.49425908
94Disinhibition (HP:0000734)1.48549398
95Esophageal neoplasm (HP:0100751)1.46144454
96Neoplasm of head and neck (HP:0012288)1.46144454
97Postaxial hand polydactyly (HP:0001162)1.43579295
98Aplasia/Hypoplasia of the lens (HP:0008063)1.43521361
99Hyperglycinuria (HP:0003108)1.41944023
100Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.41585612
101Hyperaldosteronism (HP:0000859)1.41337754
102Impaired vibration sensation in the lower limbs (HP:0002166)1.40945493
103Polydipsia (HP:0001959)1.37197735
104Abnormal drinking behavior (HP:0030082)1.37197735
105Fibular hypoplasia (HP:0003038)1.36955165
106Respiratory distress (HP:0002098)1.36899243
107Specific learning disability (HP:0001328)1.35074657
108Urinary urgency (HP:0000012)1.34109699
109Abnormality of macular pigmentation (HP:0008002)1.32436396
110Abnormality of renin-angiotensin system (HP:0000847)1.29417228
111Short thorax (HP:0010306)1.29122882
112Abnormality of chloride homeostasis (HP:0011422)1.29017002
113Nephropathy (HP:0000112)1.28854997
114Facial cleft (HP:0002006)1.28024899
115Cone-rod dystrophy (HP:0000548)1.26467773
116Decreased central vision (HP:0007663)1.21733380
117Glucose intolerance (HP:0000833)1.21693437
118Hypokalemic alkalosis (HP:0001949)1.18106587
119Hand muscle atrophy (HP:0009130)1.16621340
120Abnormal rod and cone electroretinograms (HP:0008323)1.14254475
121Abnormality of the frontal sinuses (HP:0002687)1.12714188
122Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.12356469
123Bifid scrotum (HP:0000048)1.09787330
124Fetal akinesia sequence (HP:0001989)1.07058467
125Abnormality of the distal phalanges of the toes (HP:0010182)1.06483640
126Hyponatremia (HP:0002902)1.03629251
127Retinitis pigmentosa (HP:0000510)1.00050984
128Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)0.99113052
129Abnormality of the renal cortex (HP:0011035)0.98610445
130Obstructive sleep apnea (HP:0002870)0.97184977
131Short femoral neck (HP:0100864)0.96828569
132Abnormality of monocarboxylic acid metabolism (HP:0010996)0.95452232
133Lip pit (HP:0100267)0.95399586
134Absent speech (HP:0001344)0.94845779

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.06340258
2PNCK5.96554457
3GRK15.03874795
4EPHA24.65523583
5EEF2K3.17321790
6CDC42BPA2.44406760
7NME12.41745131
8MAP3K22.10596797
9MAPKAPK31.91537012
10ERBB31.89263719
11SIK11.82834298
12TRPM71.82831652
13MST41.82509549
14STK241.81834633
15TTK1.81115912
16SMG11.73141041
17WEE11.65643898
18MAPKAPK51.61350931
19PTK2B1.54669902
20CASK1.53207937
21PRKCG1.52791682
22BMPR21.49035386
23MAP3K31.39472454
24TIE11.32280712
25RPS6KA21.25608300
26MAP3K71.23692192
27BCR1.19766493
28EPHB11.18333835
29NEK61.13496186
30NTRK31.10284734
31MST1R1.08755105
32TGFBR21.07668195
33LRRK21.02883392
34CAMK1G0.98715923
35NTRK20.96474170
36TLK10.96265668
37PRKCI0.94547597
38EPHA30.93539463
39FES0.89897756
40MARK20.88540166
41PRKCE0.87736583
42DAPK20.86626140
43PINK10.86022427
44MAP2K70.82204847
45PRKG20.81715667
46STK380.81278475
47CAMKK10.80262447
48LIMK10.79902386
49PAK20.78697653
50CSK0.78417365
51PTK60.76905788
52MAP3K40.75591502
53ERBB20.75493697
54MAPK120.75311330
55GSK3A0.74981863
56LMTK20.74191222
57FRK0.73018672
58DMPK0.72743862
59VRK10.70199176
60ROCK20.69037658
61ITK0.68733399
62TESK10.67051215
63RIPK40.65542288
64ARAF0.64429558
65MUSK0.63688998
66CAMK2A0.61678396
67PTK20.60444161
68BRSK20.60215353
69CDK30.59574763
70STK100.57722428
71MAPK70.56621370
72STK38L0.56138813
73CAMKK20.55487974
74MAP2K40.55159217
75CAMK2B0.54137364
76MYLK0.51874110
77PRKCH0.50176606
78LATS10.49332150
79NLK0.48816611
80INSRR0.47176286
81SRC0.46931454
82ACVR1B0.46719841
83IRAK10.46658763
84ICK0.46583165
85SGK10.46268688
86CAMK2G0.45504838
87TBK10.45494490
88MAP3K120.45156768
89EPHA40.44920688
90RPS6KB20.43781434
91TSSK60.42851703
92GRK50.42556621
93MAPK130.42414097
94MARK10.41672880
95HIPK20.41133999
96PRKCD0.41010051
97EPHB20.40288893
98STK160.40053645
99RPS6KC10.39296399
100RPS6KL10.39296399
101ROCK10.38924642
102PRKACA0.38673975
103FGFR30.38512706
104TEC0.38116749
105PHKG20.38016811
106PHKG10.38016811
107PRKD10.37545258
108FER0.37410982
109PRKACG0.37076413
110PIM20.35902801
111CDK50.35444528
112PAK40.34836074
113PDPK10.32232612
114PRKAA20.32184722
115DYRK1B0.31899007
116JAK10.31586075
117PASK0.31031017
118ADRBK10.30949775
119RPS6KA60.30621163
120TNK20.30522346
121FYN0.30464144
122NEK90.30384321
123GRK60.30147915
124ADRBK20.29376428
125RIPK10.28737787
126TRIB30.28338773
127PRKCQ0.28314759
128FGR0.27901543
129AURKA0.27791000
130MET0.27765876
131DDR20.27217769
132TTN0.27199765
133OXSR10.26960822
134PRKG10.26682829
135MINK10.26523123
136CSNK1E0.26493084
137ABL10.25327961
138SCYL20.24604534
139MAPK40.24443490
140CAMK2D0.23339953
141NTRK10.23169095
142PRKCA0.22505532
143DYRK1A0.22500539
144AKT20.21655991
145WNK40.21233680
146STK390.21025304
147TYK20.20352093
148SGK20.19926341
149PLK10.19822075
150CDK60.18163730
151BMPR1B0.18045554
152PBK0.17714559
153PRKCZ0.17220150
154SGK2230.16926041
155SGK4940.16926041
156TAOK10.15493466
157EGFR0.15216200
158MAP2K10.14240523

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003604.73149276
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.96891357
3Tyrosine metabolism_Homo sapiens_hsa003503.64980528
4Ovarian steroidogenesis_Homo sapiens_hsa049133.28863458
5beta-Alanine metabolism_Homo sapiens_hsa004103.10587213
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.08064374
7Caffeine metabolism_Homo sapiens_hsa002322.73678643
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.28229989
9Linoleic acid metabolism_Homo sapiens_hsa005912.20386870
10ABC transporters_Homo sapiens_hsa020101.90386685
11GnRH signaling pathway_Homo sapiens_hsa049121.84466087
12Collecting duct acid secretion_Homo sapiens_hsa049661.81622677
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.79755986
14Huntingtons disease_Homo sapiens_hsa050161.78065939
15Olfactory transduction_Homo sapiens_hsa047401.76719290
16Gastric acid secretion_Homo sapiens_hsa049711.72844186
17Sphingolipid metabolism_Homo sapiens_hsa006001.70840589
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.70663005
19Vitamin B6 metabolism_Homo sapiens_hsa007501.64247656
20Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.62145748
21Butanoate metabolism_Homo sapiens_hsa006501.58594729
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.55639892
23Circadian entrainment_Homo sapiens_hsa047131.49107345
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.47980874
25Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.44411913
26Histidine metabolism_Homo sapiens_hsa003401.43017072
27Insulin secretion_Homo sapiens_hsa049111.37099198
28GABAergic synapse_Homo sapiens_hsa047271.34993541
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.32570176
30Synaptic vesicle cycle_Homo sapiens_hsa047211.29839038
31Renin secretion_Homo sapiens_hsa049241.28208349
32Salivary secretion_Homo sapiens_hsa049701.28036660
33Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.27190378
34Nicotine addiction_Homo sapiens_hsa050331.25341782
35Morphine addiction_Homo sapiens_hsa050321.24760958
36Peroxisome_Homo sapiens_hsa041461.20412908
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.19725133
38Calcium signaling pathway_Homo sapiens_hsa040201.17495933
39Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.15399081
40Glutathione metabolism_Homo sapiens_hsa004801.15147562
41Tight junction_Homo sapiens_hsa045301.14560934
42Vibrio cholerae infection_Homo sapiens_hsa051101.14071663
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.13613065
44Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12547717
45Arachidonic acid metabolism_Homo sapiens_hsa005901.10699476
46Carbohydrate digestion and absorption_Homo sapiens_hsa049731.10381962
47Hippo signaling pathway_Homo sapiens_hsa043901.05540747
48Starch and sucrose metabolism_Homo sapiens_hsa005001.05534243
49Propanoate metabolism_Homo sapiens_hsa006401.05479589
50PPAR signaling pathway_Homo sapiens_hsa033201.04997330
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.04790305
52Prolactin signaling pathway_Homo sapiens_hsa049171.04518493
53Leukocyte transendothelial migration_Homo sapiens_hsa046701.03548453
54Phagosome_Homo sapiens_hsa041451.02339723
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02121392
56Vascular smooth muscle contraction_Homo sapiens_hsa042701.01383076
57cAMP signaling pathway_Homo sapiens_hsa040240.98551965
58Cocaine addiction_Homo sapiens_hsa050300.97145018
59Oxytocin signaling pathway_Homo sapiens_hsa049210.92638597
60Estrogen signaling pathway_Homo sapiens_hsa049150.92151303
61Amphetamine addiction_Homo sapiens_hsa050310.91028390
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90735691
63Glutamatergic synapse_Homo sapiens_hsa047240.90425020
64AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.90258381
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89727296
66Tryptophan metabolism_Homo sapiens_hsa003800.89702483
67Chemical carcinogenesis_Homo sapiens_hsa052040.89432115
68Mineral absorption_Homo sapiens_hsa049780.85047597
69Long-term depression_Homo sapiens_hsa047300.83549075
70Rheumatoid arthritis_Homo sapiens_hsa053230.81886389
71Melanogenesis_Homo sapiens_hsa049160.81787295
72Circadian rhythm_Homo sapiens_hsa047100.81178005
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.80306332
74Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80122987
75Gap junction_Homo sapiens_hsa045400.79897629
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.79484657
77Taste transduction_Homo sapiens_hsa047420.79330355
78Prion diseases_Homo sapiens_hsa050200.79128654
79Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.76594131
80Phototransduction_Homo sapiens_hsa047440.76335743
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.76064476
82Thyroid hormone synthesis_Homo sapiens_hsa049180.75802488
83Axon guidance_Homo sapiens_hsa043600.75393487
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73047984
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72929274
86ECM-receptor interaction_Homo sapiens_hsa045120.72116522
87Choline metabolism in cancer_Homo sapiens_hsa052310.71832058
88Cholinergic synapse_Homo sapiens_hsa047250.70321415
89Complement and coagulation cascades_Homo sapiens_hsa046100.69103312
90Hedgehog signaling pathway_Homo sapiens_hsa043400.68181494
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.67288108
92Basal cell carcinoma_Homo sapiens_hsa052170.67010685
93Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65278981
94Nitrogen metabolism_Homo sapiens_hsa009100.64578604
95Dilated cardiomyopathy_Homo sapiens_hsa054140.64158541
96Pyruvate metabolism_Homo sapiens_hsa006200.62940550
97Hepatitis C_Homo sapiens_hsa051600.61622144
98Adherens junction_Homo sapiens_hsa045200.61088078
99Fatty acid biosynthesis_Homo sapiens_hsa000610.60834568
100Bile secretion_Homo sapiens_hsa049760.59942358
101Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59403366
102Arginine and proline metabolism_Homo sapiens_hsa003300.59284748
103Wnt signaling pathway_Homo sapiens_hsa043100.58711700
104Dopaminergic synapse_Homo sapiens_hsa047280.57128232
105Retinol metabolism_Homo sapiens_hsa008300.56504553
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56466327
107Focal adhesion_Homo sapiens_hsa045100.55302423
108Fatty acid degradation_Homo sapiens_hsa000710.53279304
109Notch signaling pathway_Homo sapiens_hsa043300.51093382
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50785315
111Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50016533
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49087175
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.48729346
114Hematopoietic cell lineage_Homo sapiens_hsa046400.47746327
115Rap1 signaling pathway_Homo sapiens_hsa040150.47499638
116Amoebiasis_Homo sapiens_hsa051460.45571803
117Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.45163012
118Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44394199
119Glycerolipid metabolism_Homo sapiens_hsa005610.44267135
120Pertussis_Homo sapiens_hsa051330.44129206
121Fatty acid elongation_Homo sapiens_hsa000620.43781512
1222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.42601517
123Vitamin digestion and absorption_Homo sapiens_hsa049770.42409411
124Arginine biosynthesis_Homo sapiens_hsa002200.42187741
125Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.41530627
126alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.39015203
127Serotonergic synapse_Homo sapiens_hsa047260.34979953
128Metabolic pathways_Homo sapiens_hsa011000.31070109
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30489673
130Pancreatic secretion_Homo sapiens_hsa049720.28254477
131Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25723078
132Cyanoamino acid metabolism_Homo sapiens_hsa004600.25554422
133Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24217048
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.22039522
135Lysosome_Homo sapiens_hsa041420.18514346
136Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.18112869
137Glycosaminoglycan degradation_Homo sapiens_hsa005310.17852295
138Insulin resistance_Homo sapiens_hsa049310.17578446
139Sphingolipid signaling pathway_Homo sapiens_hsa040710.15851120
140Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.15186298
141Type I diabetes mellitus_Homo sapiens_hsa049400.13479605
142Regulation of autophagy_Homo sapiens_hsa041400.11870726
143Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.07493471
144Ether lipid metabolism_Homo sapiens_hsa005650.06739863
145Allograft rejection_Homo sapiens_hsa053300.03830611

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