CDHR5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)7.38764155
2regulation of guanylate cyclase activity (GO:0031282)7.28988858
3intestinal cholesterol absorption (GO:0030299)7.15675336
4NADH metabolic process (GO:0006734)6.88912721
5fat-soluble vitamin biosynthetic process (GO:0042362)6.39646012
6drug catabolic process (GO:0042737)5.82696988
7lipoprotein transport (GO:0042953)5.69136045
8angiotensin maturation (GO:0002003)5.58175823
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.57322259
10flavonoid metabolic process (GO:0009812)5.45040374
11positive regulation of guanylate cyclase activity (GO:0031284)5.34551759
12bile acid and bile salt transport (GO:0015721)5.24726791
13regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.15660095
14endocrine process (GO:0050886)5.15660095
15regulation of systemic arterial blood pressure by hormone (GO:0001990)5.15660095
16regulation of bile acid biosynthetic process (GO:0070857)4.99767692
17diacylglycerol metabolic process (GO:0046339)4.84834315
18drug transmembrane transport (GO:0006855)4.84511511
19regulation of triglyceride catabolic process (GO:0010896)4.78888492
20phospholipid efflux (GO:0033700)4.75065722
21cysteine metabolic process (GO:0006534)4.74527911
22regulation of cholesterol esterification (GO:0010872)4.73891114
23sulfur amino acid catabolic process (GO:0000098)4.73010628
24regulation of systemic arterial blood pressure (GO:0003073)4.67287784
25regulation of cellular extravasation (GO:0002691)4.66622144
26L-phenylalanine catabolic process (GO:0006559)4.61961398
27erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.61961398
28L-phenylalanine metabolic process (GO:0006558)4.57029654
29erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.57029654
30homocysteine metabolic process (GO:0050667)4.56042251
31renal system process involved in regulation of blood volume (GO:0001977)4.54939466
32negative regulation of cholesterol transport (GO:0032375)4.52486634
33negative regulation of sterol transport (GO:0032372)4.52486634
34exogenous drug catabolic process (GO:0042738)4.51259885
35receptor guanylyl cyclase signaling pathway (GO:0007168)4.47702079
36regulation of cGMP biosynthetic process (GO:0030826)4.47334696
37drug transport (GO:0015893)4.42599708
38regulation of cholesterol homeostasis (GO:2000188)4.41786815
39aromatic amino acid family catabolic process (GO:0009074)4.34890941
40virion attachment to host cell (GO:0019062)4.33320577
41adhesion of symbiont to host cell (GO:0044650)4.33320577
42positive regulation of triglyceride lipase activity (GO:0061365)4.32250043
43positive regulation of lipoprotein lipase activity (GO:0051006)4.32250043
44plasma lipoprotein particle assembly (GO:0034377)4.30483524
45urea cycle (GO:0000050)4.29725641
46urea metabolic process (GO:0019627)4.29725641
47peptide catabolic process (GO:0043171)4.28782888
48lysine metabolic process (GO:0006553)4.25908139
49lysine catabolic process (GO:0006554)4.25908139
50high-density lipoprotein particle remodeling (GO:0034375)4.21904307
51regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.20952476
52cellular glucuronidation (GO:0052695)4.18262763
53indole-containing compound catabolic process (GO:0042436)4.13902591
54indolalkylamine catabolic process (GO:0046218)4.13902591
55tryptophan catabolic process (GO:0006569)4.13902591
56lipoprotein metabolic process (GO:0042157)4.12566688
57peptide hormone processing (GO:0016486)4.10531600
58glyoxylate metabolic process (GO:0046487)4.10169488
59fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.05481578
60protein-lipid complex remodeling (GO:0034368)4.04751576
61macromolecular complex remodeling (GO:0034367)4.04751576
62plasma lipoprotein particle remodeling (GO:0034369)4.04751576
63cholesterol efflux (GO:0033344)4.03188889
64protein-lipid complex assembly (GO:0065005)4.02435742
65cholesterol homeostasis (GO:0042632)4.02260206
66reverse cholesterol transport (GO:0043691)4.02115637
67sterol homeostasis (GO:0055092)4.00168056
68alkaloid metabolic process (GO:0009820)3.98765879
693-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.97428794
70purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.97428794
71kynurenine metabolic process (GO:0070189)3.92982793
72nitrogen cycle metabolic process (GO:0071941)3.92843492
73positive regulation of pseudopodium assembly (GO:0031274)3.91810505
74very-low-density lipoprotein particle assembly (GO:0034379)3.89962223
75antibacterial humoral response (GO:0019731)3.88089874
76tryptophan metabolic process (GO:0006568)3.84839544
77bile acid metabolic process (GO:0008206)3.84544198
78glucuronate metabolic process (GO:0019585)3.83280512
79uronic acid metabolic process (GO:0006063)3.83280512
80antimicrobial humoral response (GO:0019730)3.81148459
81urate metabolic process (GO:0046415)3.79628857
82regulation of vitamin metabolic process (GO:0030656)3.77400567
83drug metabolic process (GO:0017144)3.77103090
84adhesion of symbiont to host (GO:0044406)3.75773849
85modified amino acid transport (GO:0072337)3.73598524
86vitamin transmembrane transport (GO:0035461)3.73020214
87acylglycerol homeostasis (GO:0055090)3.70675177
88triglyceride homeostasis (GO:0070328)3.70675177
89regulation of cGMP metabolic process (GO:0030823)3.69391423
90amino-acid betaine metabolic process (GO:0006577)3.68751474
91ethanol oxidation (GO:0006069)3.64888827
92UDP-N-acetylglucosamine metabolic process (GO:0006047)3.64203923
93digestion (GO:0007586)3.62765019
94vitamin A metabolic process (GO:0006776)3.62744460
95glycolipid catabolic process (GO:0019377)3.61997952
96cellular ketone body metabolic process (GO:0046950)3.61689464
97alpha-linolenic acid metabolic process (GO:0036109)3.61663151
98glycosphingolipid catabolic process (GO:0046479)3.60016868
99phospholipid homeostasis (GO:0055091)3.57169509
100vitamin transport (GO:0051180)3.56804647
101cellular response to nitric oxide (GO:0071732)3.54962157
102hormone catabolic process (GO:0042447)3.54287679
103regulation of pseudopodium assembly (GO:0031272)3.50343162
104bile acid biosynthetic process (GO:0006699)3.50122055
105cGMP-mediated signaling (GO:0019934)3.49477919
106arginine metabolic process (GO:0006525)3.48387344
107positive regulation of respiratory burst (GO:0060267)3.45688732
108glucose 6-phosphate metabolic process (GO:0051156)3.44642201
109renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.43523268
110digestive system process (GO:0022600)3.42416564
111sulfate transmembrane transport (GO:1902358)3.41849383
112plasma lipoprotein particle organization (GO:0071827)3.37026890
113glutamine family amino acid biosynthetic process (GO:0009084)3.36775174
114bundle of His cell to Purkinje myocyte communication (GO:0086069)3.34681514
115serine family amino acid catabolic process (GO:0009071)3.33150936
116positive regulation of fatty acid biosynthetic process (GO:0045723)3.31722773
117transcytosis (GO:0045056)3.30203133
118fructose metabolic process (GO:0006000)3.28643260
119cellular modified amino acid catabolic process (GO:0042219)3.27978376
120short-chain fatty acid metabolic process (GO:0046459)3.26792077
121protein-lipid complex subunit organization (GO:0071825)3.26770542
122positive regulation of lipid catabolic process (GO:0050996)3.26097633
123glutamate metabolic process (GO:0006536)3.25531488
124phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.24910608
125actin filament depolymerization (GO:0030042)3.24718610
126fat-soluble vitamin metabolic process (GO:0006775)3.24559126
127response to nitric oxide (GO:0071731)3.23535540
128cholesterol transport (GO:0030301)3.23123356
129sterol transport (GO:0015918)3.23123356
130omega-hydroxylase P450 pathway (GO:0097267)3.20731069
131positive regulation of glycoprotein biosynthetic process (GO:0010560)3.20553679
132antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.18317968
133plasma lipoprotein particle clearance (GO:0034381)3.16808629
134vitamin biosynthetic process (GO:0009110)3.16292343
135lipid homeostasis (GO:0055088)3.16210750
136aromatic amino acid family metabolic process (GO:0009072)3.15554979
137nucleoside diphosphate biosynthetic process (GO:0009133)3.14582553
138cellular response to reactive nitrogen species (GO:1902170)3.14287645
139drinking behavior (GO:0042756)3.13508608
140positive regulation of cGMP biosynthetic process (GO:0030828)3.12864571
141positive regulation of triglyceride metabolic process (GO:0090208)3.12832376
142maintenance of gastrointestinal epithelium (GO:0030277)3.12443546
143epoxygenase P450 pathway (GO:0019373)3.11343820
144ketone body metabolic process (GO:1902224)3.10245768
145fatty acid beta-oxidation (GO:0006635)3.09771885
146sulfur compound transport (GO:0072348)3.08740669
147calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.08042311
148benzene-containing compound metabolic process (GO:0042537)3.07147685
149antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.05853261
150sexual reproduction (GO:0019953)3.05831334
151ethanol metabolic process (GO:0006067)3.04180179
152response to nitrosative stress (GO:0051409)3.03534833
153leukotriene metabolic process (GO:0006691)3.00372520
154glycerol metabolic process (GO:0006071)3.00150545
155antigen processing and presentation of endogenous antigen (GO:0019883)2.95862517

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.02460612
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.88506584
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.48411567
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.81774702
5TP63_17297297_ChIP-ChIP_HaCaT_Human4.55526390
6EGR1_23403033_ChIP-Seq_LIVER_Mouse4.34214935
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.96245303
8CDX2_20551321_ChIP-Seq_CACO-2_Human3.84210728
9FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.25310932
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.99365028
11CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.88983914
12SOX2_27498859_Chip-Seq_STOMACH_Mouse2.86823731
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.86689207
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.72179629
15IRF8_22096565_ChIP-ChIP_GC-B_Human2.50182019
16GATA4_25053715_ChIP-Seq_YYC3_Human2.35859018
17TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.17704378
18GATA6_25053715_ChIP-Seq_YYC3_Human2.02588647
19CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.91006555
20SOX2_20726797_ChIP-Seq_SW620_Human1.90318622
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.84363662
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.65013040
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.64745442
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.58223304
25HNF4A_19822575_ChIP-Seq_HepG2_Human1.57624055
26CLOCK_20551151_ChIP-Seq_293T_Human1.57181519
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.57029342
28ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.56686320
29FOXA2_19822575_ChIP-Seq_HepG2_Human1.54870570
30NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52940101
31TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.50292186
32PPAR_26484153_Chip-Seq_NCI-H1993_Human1.48950045
33TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38764695
34RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.37138377
35ESR1_21235772_ChIP-Seq_MCF-7_Human1.37106970
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.36708237
37SRY_22984422_ChIP-ChIP_TESTIS_Rat1.36069882
38FOXO3_23340844_ChIP-Seq_DLD1_Human1.32592158
39TET1_21451524_ChIP-Seq_MESCs_Mouse1.32194828
40SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25370361
41CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.25310328
42BCL6_27268052_Chip-Seq_Bcells_Human1.24888834
43RACK7_27058665_Chip-Seq_MCF-7_Human1.24679740
44SA1_27219007_Chip-Seq_Bcells_Human1.24652577
45BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.22526564
46SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15857802
47JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.15331853
48ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15099728
49ESR1_20079471_ChIP-ChIP_T-47D_Human1.09992915
50CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09962958
51FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09851405
52CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.09032421
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08974261
54KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.08811450
55KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.08692260
56IRF8_21731497_ChIP-ChIP_J774_Mouse1.07566279
57TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06963414
58GATA2_19941826_ChIP-Seq_K562_Human1.05623977
59DNAJC2_21179169_ChIP-ChIP_NT2_Human1.04746633
60RUNX1_27514584_Chip-Seq_MCF-7_Human1.03854432
61AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.02335350
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01658054
63ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.01255642
64LXR_22292898_ChIP-Seq_THP-1_Human0.99354073
65FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.98028754
66EGR1_19032775_ChIP-ChIP_M12_Human0.97236396
67ZNF263_19887448_ChIP-Seq_K562_Human0.96079386
68VDR_24763502_ChIP-Seq_THP-1_Human0.95453764
69KLF5_25053715_ChIP-Seq_YYC3_Human0.94529541
70SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.94044717
71BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.92536333
72DROSHA_22980978_ChIP-Seq_HELA_Human0.90754010
73SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89726063
74GATA2_22383799_ChIP-Seq_G1ME_Mouse0.89615645
75PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.89169561
76ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88594925
77GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88584497
78SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.88303933
79* ATF3_27146783_Chip-Seq_COLON_Human0.88171437
80MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87577121
81ELK3_25401928_ChIP-Seq_HUVEC_Human0.86722916
82CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86211445
83NANOG_20526341_ChIP-Seq_ESCs_Human0.85631265
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.85478836
85TCF4_18268006_ChIP-ChIP_LS174T_Human0.85455636
86CREB1_26743006_Chip-Seq_LNCaP_Human0.85054888
87PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84960957
88FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.84886478
89STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.84758780
90GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.84408770
91TP63_22573176_ChIP-Seq_HFKS_Human0.83958340
92VDR_22108803_ChIP-Seq_LS180_Human0.83117304
93CEBPB_22108803_ChIP-Seq_LS180_Human0.82535512
94TCF3_18692474_ChIP-Seq_MEFs_Mouse0.82182335
95Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.82120211
96FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81963761
97EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.81796681
98SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.81509949
99GATA1_22025678_ChIP-Seq_K562_Human0.81499355
100CTCF_27219007_Chip-Seq_ERYTHROID_Human0.80778530
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.80645891
102OCT4_18692474_ChIP-Seq_MEFs_Mouse0.80303434
103FOXA1_25552417_ChIP-Seq_VCAP_Human0.80025954
104RAD21_21589869_ChIP-Seq_MESCs_Mouse0.79467866
105AR_21909140_ChIP-Seq_LNCAP_Human0.78741288
106RARA_24833708_ChIP-Seq_LIVER_Mouse0.78456788
107PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.77619497
108SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.76176573
109STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.74421242
110NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.74409393
111KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74092452
112HTT_18923047_ChIP-ChIP_STHdh_Human0.73098291
113GATA1_19941826_ChIP-Seq_K562_Human0.72899046
114SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.72032220
115GATA3_24758297_ChIP-Seq_MCF-7_Human0.71856406
116MYC_19915707_ChIP-ChIP_AK7_Human0.71475364
117PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.69308548
118STAT3_1855785_ChIP-Seq_MESCs_Mouse0.68920984
119P63_26484246_Chip-Seq_KERATINOCYTES_Human0.68493466
120CDX2_22108803_ChIP-Seq_LS180_Human0.68253556
121ZNF217_24962896_ChIP-Seq_MCF-7_Human0.68090682
122CTCF_27219007_Chip-Seq_Bcells_Human0.65587548
123RXRA_24833708_ChIP-Seq_LIVER_Mouse0.65441860
124NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.64971694
125BCAT_22108803_ChIP-Seq_LS180_Human0.64414668
126CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.64064124
127TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.63778417
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.63657059
129BCOR_27268052_Chip-Seq_Bcells_Human0.63445624
130TAF2_19829295_ChIP-Seq_ESCs_Human0.63002865

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis9.11846538
2MP0002139_abnormal_hepatobiliary_system6.14630943
3MP0005085_abnormal_gallbladder_physiolo5.03206757
4MP0001666_abnormal_nutrient_absorption4.58551472
5MP0008875_abnormal_xenobiotic_pharmacok4.36896080
6MP0005365_abnormal_bile_salt4.23536314
7MP0003252_abnormal_bile_duct3.79658917
8MP0009840_abnormal_foam_cell3.24448966
9MP0010234_abnormal_vibrissa_follicle3.10887561
10MP0010329_abnormal_lipoprotein_level2.93083447
11MP0004019_abnormal_vitamin_homeostasis2.73387743
12MP0003806_abnormal_nucleotide_metabolis2.62838806
13MP0004264_abnormal_extraembryonic_tissu2.56256542
14MP0005332_abnormal_amino_acid2.46586066
15MP0005409_darkened_coat_color2.18119376
16MP0003191_abnormal_cellular_cholesterol2.04875836
17MP0004043_abnormal_pH_regulation2.01559814
18MP0003866_abnormal_defecation1.92589787
19MP0002822_catalepsy1.87041019
20MP0009643_abnormal_urine_homeostasis1.83822092
21MP0000462_abnormal_digestive_system1.79183747
22MP0003878_abnormal_ear_physiology1.69443566
23MP0005377_hearing/vestibular/ear_phenot1.69443566
24MP0003705_abnormal_hypodermis_morpholog1.64101944
25MP0003868_abnormal_feces_composition1.60500496
26MP0005670_abnormal_white_adipose1.58459531
27MP0002118_abnormal_lipid_homeostasis1.58402052
28MP0002138_abnormal_hepatobiliary_system1.58213381
29MP0000678_abnormal_parathyroid_gland1.54213227
30MP0000609_abnormal_liver_physiology1.54141079
31MP0003195_calcinosis1.44362428
32MP0003183_abnormal_peptide_metabolism1.44000790
33MP0005084_abnormal_gallbladder_morpholo1.41509518
34MP0001663_abnormal_digestive_system1.41271647
35MP0005636_abnormal_mineral_homeostasis1.37626966
36MP0005319_abnormal_enzyme/_coenzyme1.36992956
37MP0010155_abnormal_intestine_physiology1.34842376
38MP0005381_digestive/alimentary_phenotyp1.34155903
39MP0003300_gastrointestinal_ulcer1.32019755
40MP0000538_abnormal_urinary_bladder1.31979355
41MP0004858_abnormal_nervous_system1.30610570
42MP0005451_abnormal_body_composition1.29219928
43MP0001765_abnormal_ion_homeostasis1.28436000
44MP0001188_hyperpigmentation1.27616631
45MP0001873_stomach_inflammation1.20906861
46MP0001764_abnormal_homeostasis1.17735675
47MP0004782_abnormal_surfactant_physiolog1.17427731
48MP0005584_abnormal_enzyme/coenzyme_acti1.16597151
49MP0004147_increased_porphyrin_level1.15195365
50MP0000477_abnormal_intestine_morphology1.14737475
51MP0005083_abnormal_biliary_tract1.14513841
52MP0002796_impaired_skin_barrier1.11209239
53MP0001664_abnormal_digestion1.09371400
54MP0002876_abnormal_thyroid_physiology1.03628735
55MP0002254_reproductive_system_inflammat1.03305067
56MP0002136_abnormal_kidney_physiology1.02464683
57MP0001756_abnormal_urination1.02062789
58MP0005167_abnormal_blood-brain_barrier1.01238591
59MP0003283_abnormal_digestive_organ0.93923873
60MP0000537_abnormal_urethra_morphology0.92289557
61MP0004270_analgesia0.92147208
62MP0010352_gastrointestinal_tract_polyps0.91182740
63MP0005535_abnormal_body_temperature0.90774597
64MP0005448_abnormal_energy_balance0.88246384
65MP0009785_altered_susceptibility_to0.82961100
66MP0001501_abnormal_sleep_pattern0.82715409
67MP0009697_abnormal_copulation0.82350727
68MP0000490_abnormal_crypts_of0.78736326
69MP0009053_abnormal_anal_canal0.76581606
70MP0009642_abnormal_blood_homeostasis0.76010253
71MP0005166_decreased_susceptibility_to0.72176779
72MP0003436_decreased_susceptibility_to0.72110209
73MP0009764_decreased_sensitivity_to0.70709526
74MP0000598_abnormal_liver_morphology0.70687751
75MP0003724_increased_susceptibility_to0.68969084
76MP0008872_abnormal_physiological_respon0.68348507
77MP0002166_altered_tumor_susceptibility0.67612143
78MP0003303_peritoneal_inflammation0.66640601
79MP0000566_synostosis0.66268761
80MP0005025_abnormal_response_to0.65433899
81MP0000604_amyloidosis0.65042046
82MP0000465_gastrointestinal_hemorrhage0.64833845
83MP0005501_abnormal_skin_physiology0.64286029
84MP0000249_abnormal_blood_vessel0.64280132
85MP0005058_abnormal_lysosome_morphology0.64116636
86MP0008469_abnormal_protein_level0.62190915
87MP0005266_abnormal_metabolism0.61316059
88MP0005376_homeostasis/metabolism_phenot0.60698961
89MP0004947_skin_inflammation0.60449238
90MP0001835_abnormal_antigen_presentation0.59402865
91MP0002098_abnormal_vibrissa_morphology0.59065778
92MP0009765_abnormal_xenobiotic_induced0.58475464
93MP0000467_abnormal_esophagus_morphology0.58428144
94MP0001849_ear_inflammation0.58004799
95MP0001485_abnormal_pinna_reflex0.57541616
96MP0009384_cardiac_valve_regurgitation0.57525578
97MP0003453_abnormal_keratinocyte_physiol0.57064702
98MP0002896_abnormal_bone_mineralization0.56098305
99MP0002089_abnormal_postnatal_growth/wei0.55583644
100MP0009333_abnormal_splenocyte_physiolog0.54867473
101MP0005666_abnormal_adipose_tissue0.54410590
102MP0003638_abnormal_response/metabolism_0.53460406
103MP0010678_abnormal_skin_adnexa0.53334613
104MP0006054_spinal_hemorrhage0.53213272
105MP0001790_abnormal_immune_system0.52320846
106MP0005387_immune_system_phenotype0.52320846
107MP0003718_maternal_effect0.51879940
108MP0000230_abnormal_systemic_arterial0.51545743
109MP0006082_CNS_inflammation0.50385606
110MP0009379_abnormal_foot_pigmentation0.49336065
111MP0002078_abnormal_glucose_homeostasis0.48924827
112MP0001881_abnormal_mammary_gland0.48111295
113MP0008873_increased_physiological_sensi0.45264950
114MP0002971_abnormal_brown_adipose0.44830393
115MP0008004_abnormal_stomach_pH0.44535155
116MP0001216_abnormal_epidermal_layer0.44480865
117MP0003656_abnormal_erythrocyte_physiolo0.44471912
118MP0003186_abnormal_redox_activity0.44242633
119MP0005408_hypopigmentation0.43809814
120MP0003879_abnormal_hair_cell0.43069238
121MP0002396_abnormal_hematopoietic_system0.42929718
122MP0005334_abnormal_fat_pad0.42483889
123MP0006036_abnormal_mitochondrial_physio0.41943322
124MP0001533_abnormal_skeleton_physiology0.41840960
125MP0009763_increased_sensitivity_to0.41329828
126MP0001845_abnormal_inflammatory_respons0.40841840
127MP0009780_abnormal_chondrocyte_physiolo0.39358393
128MP0003953_abnormal_hormone_level0.37442139
129MP0009115_abnormal_fat_cell0.35850785
130MP0003329_amyloid_beta_deposits0.33663145

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glutamine family amino acid metabolism (HP:0010902)6.49098871
2Hypobetalipoproteinemia (HP:0003563)5.82699025
3Ileus (HP:0002595)5.19896141
4Intrahepatic cholestasis (HP:0001406)5.18203554
5Abnormality of monocarboxylic acid metabolism (HP:0010996)4.95505362
6Systemic lupus erythematosus (HP:0002725)4.93016521
7Xanthomatosis (HP:0000991)4.74652455
8Malnutrition (HP:0004395)4.67612525
9Hyperglycinuria (HP:0003108)4.56057350
10Conjugated hyperbilirubinemia (HP:0002908)4.35981834
11Abnormality of proline metabolism (HP:0010907)4.21814377
12Hydroxyprolinuria (HP:0003080)4.21814377
13Fat malabsorption (HP:0002630)4.21319594
14Abnormality of aromatic amino acid family metabolism (HP:0004338)4.17938966
15Hypolipoproteinemia (HP:0010981)4.00611123
16Acanthocytosis (HP:0001927)3.95806498
17Hyperactive renin-angiotensin system (HP:0000841)3.88619904
18Abnormality of aspartate family amino acid metabolism (HP:0010899)3.82456921
19Abnormality of serine family amino acid metabolism (HP:0010894)3.79700214
20Abnormality of glycine metabolism (HP:0010895)3.79700214
21Abnormality of sulfur amino acid metabolism (HP:0004339)3.70989795
22Hyperammonemia (HP:0001987)3.68065230
23Metabolic alkalosis (HP:0200114)3.63878348
24Deep venous thrombosis (HP:0002625)3.63082416
25Abnormality of purine metabolism (HP:0004352)3.59133391
26Decreased circulating renin level (HP:0003351)3.52099028
27Right ventricular cardiomyopathy (HP:0011663)3.45381776
28Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.43252832
29Wide cranial sutures (HP:0010537)3.30691542
30Thin bony cortex (HP:0002753)3.24817502
31Epidermoid cyst (HP:0200040)3.22725872
32Abnormality of nucleobase metabolism (HP:0010932)3.19798584
33Hemorrhage of the eye (HP:0011885)3.11961708
34Gout (HP:0001997)3.11724119
35Abnormality of chloride homeostasis (HP:0011422)3.11701365
36Alkalosis (HP:0001948)3.07014419
37Congenital sensorineural hearing impairment (HP:0008527)3.04642792
38Ketosis (HP:0001946)3.03839809
39Abnormality of urine glucose concentration (HP:0011016)3.03649837
40Glycosuria (HP:0003076)3.03649837
41Abdominal distention (HP:0003270)3.02546782
42Prolonged partial thromboplastin time (HP:0003645)2.95827365
43Hypoglycemic coma (HP:0001325)2.95687639
44Proximal tubulopathy (HP:0000114)2.94070902
45Abnormality of fatty-acid metabolism (HP:0004359)2.90678761
46Metabolic acidosis (HP:0001942)2.88021602
47Megaloblastic anemia (HP:0001889)2.87857130
48Hypercholesterolemia (HP:0003124)2.87419405
49Ketoacidosis (HP:0001993)2.83038029
50Autoimmune thrombocytopenia (HP:0001973)2.79902559
51Widely patent fontanelles and sutures (HP:0004492)2.77636293
52Abnormal tarsal ossification (HP:0008369)2.76402380
53Glomerulonephritis (HP:0000099)2.74845924
54Hypoalphalipoproteinemia (HP:0003233)2.71696002
55Hyperglycinemia (HP:0002154)2.67309554
56Hyperparathyroidism (HP:0000843)2.65309729
57Hyperuricemia (HP:0002149)2.64872624
58Increased purine levels (HP:0004368)2.64872624
59Nephrolithiasis (HP:0000787)2.64157027
60Hyperlipoproteinemia (HP:0010980)2.62434509
61Hyperbilirubinemia (HP:0002904)2.58856728
62Abnormality of dicarboxylic acid metabolism (HP:0010995)2.54892550
63Dicarboxylic aciduria (HP:0003215)2.54892550
64Complement deficiency (HP:0004431)2.54854821
65Posterior subcapsular cataract (HP:0007787)2.54485794
66Flat acetabular roof (HP:0003180)2.52981095
67Dehydration (HP:0001944)2.51837597
68Cupped ribs (HP:0000887)2.51361278
69Focal segmental glomerulosclerosis (HP:0000097)2.50630637
70Poikilocytosis (HP:0004447)2.50468119
71Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.49321405
72Villous atrophy (HP:0011473)2.48186170
73Abnormality of small intestinal villus morphology (HP:0011472)2.48186170
74Eczematoid dermatitis (HP:0000976)2.47491869
75Vascular calcification (HP:0004934)2.46207418
76Late onset (HP:0003584)2.45541057
77Hypotension (HP:0002615)2.43984185
78Abnormality of pyrimidine metabolism (HP:0004353)2.41128968
79Abnormality of vitamin metabolism (HP:0100508)2.40418653
80Chronic diarrhea (HP:0002028)2.38048569
81Generalized aminoaciduria (HP:0002909)2.35046737
82Facial shape deformation (HP:0011334)2.33393303
83Potter facies (HP:0002009)2.33393303
84Hyperphosphaturia (HP:0003109)2.33147841
85Nephritis (HP:0000123)2.33122430
86Abnormality of renin-angiotensin system (HP:0000847)2.32154438
87Confusion (HP:0001289)2.29699761
88Pigmentary retinal degeneration (HP:0001146)2.26250545
89Abnormality of the common coagulation pathway (HP:0010990)2.25606854
90Abnormality of the vitamin B12 metabolism (HP:0004341)2.24069053
91Steatorrhea (HP:0002570)2.21581153
92Delayed epiphyseal ossification (HP:0002663)2.20619837
93Lethargy (HP:0001254)2.20307308
94Enlarged epiphyses (HP:0010580)2.19279962
95Pancreatitis (HP:0001733)2.19066819
96Abnormal cartilage morphology (HP:0002763)2.17983712
97Abnormality of vitamin B metabolism (HP:0004340)2.16608033
98Sensorimotor neuropathy (HP:0007141)2.16538942
99Cardiovascular calcification (HP:0011915)2.16314817
100Cerebral palsy (HP:0100021)2.12045796
101Esophageal varix (HP:0002040)2.10621251
102Renal tubular acidosis (HP:0001947)2.06695292
103Vomiting (HP:0002013)2.05593887
104Rickets (HP:0002748)2.04425670
105Irritability (HP:0000737)2.02793864
106Nausea (HP:0002018)2.02086099
107Abnormal glucose tolerance (HP:0001952)2.01868521
108Hyperphosphatemia (HP:0002905)2.01807370
109Cholecystitis (HP:0001082)2.01613789
110Abnormal gallbladder physiology (HP:0012438)2.01613789
111Gingivitis (HP:0000230)2.01472775
112Subcapsular cataract (HP:0000523)2.01243106
113Abnormal urine phosphate concentration (HP:0012599)2.00239139
114Hypophosphatemia (HP:0002148)1.99928271
115Hyperaldosteronism (HP:0000859)1.99850580
116Gastrointestinal dysmotility (HP:0002579)1.99627653
117Symptomatic seizures (HP:0011145)1.99191193
118Increased circulating renin level (HP:0000848)1.98087588
119Joint hemorrhage (HP:0005261)1.96736826
120Delayed CNS myelination (HP:0002188)1.96655897
121Abnormality of the costochondral junction (HP:0000919)1.96252125
122Abnormality of methionine metabolism (HP:0010901)1.94338493
123Abnormal urine output (HP:0012590)1.92739793
124Protuberant abdomen (HP:0001538)1.90473324
125Growth hormone excess (HP:0000845)1.90130387
126Abnormality of complement system (HP:0005339)1.90075192
127Glomerulosclerosis (HP:0000096)1.89859811
128Abnormality of magnesium homeostasis (HP:0004921)1.85094886
129Abnormal enzyme/coenzyme activity (HP:0012379)1.83336218
130Abnormality of alkaline phosphatase activity (HP:0004379)1.82570851
131Pili torti (HP:0003777)1.81993054
132Multiple lipomas (HP:0001012)1.81594929
133Hypokalemia (HP:0002900)1.71290850
134Segmental peripheral demyelination/remyelination (HP:0003481)1.69868892
135Abnormal hair laboratory examination (HP:0003328)1.65157760
136Bone pain (HP:0002653)1.64882584

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.07259182
2MST1R5.07505733
3FRK5.07300246
4MST44.15353754
5LMTK23.13116100
6GRK62.83426105
7ERN12.77019119
8MAP2K22.60101155
9TAOK32.56065243
10PRKG22.46826749
11NME12.46693240
12PIK3CA2.34334023
13RIPK12.33234325
14WNK42.21962321
15PTK62.21426193
16EPHB22.17277473
17BCKDK2.13031687
18MAP3K21.88958627
19MAP3K101.77890748
20MET1.73593549
21FGFR41.72619310
22EPHA21.68309006
23OXSR11.64616511
24NUAK11.61721055
25MAP4K11.54864016
26MAP3K71.53712714
27EPHA31.53591522
28AKT31.52126860
29MYLK1.46300057
30PRPF4B1.45846676
31WNK31.45402081
32TAOK11.31085300
33MAPK111.20822882
34ERBB41.18864631
35TESK11.17269168
36KSR21.14939580
37PTK21.12831607
38STK38L1.11751150
39EPHB11.10355654
40MAP3K121.09640135
41ERBB21.07802752
42LATS11.07305255
43MAP2K11.06583320
44FGFR31.05129466
45EPHA41.04788267
46PRKAA21.04044204
47STK241.03363344
48TNIK1.02948135
49CDC42BPA1.01391167
50SIK10.94664014
51INSRR0.89760356
52STK100.88477062
53MAP3K110.88472106
54TBK10.88015310
55MAP2K60.87317386
56PRKCI0.83646854
57TESK20.83216923
58PKN20.82090162
59FER0.76949899
60MAP3K30.76661122
61PDPK10.74630043
62NLK0.73573954
63STK390.72156420
64MATK0.71257363
65MAP3K10.71112268
66MAP3K80.70727419
67PAK40.65989286
68BMX0.62095996
69TRIB30.62053646
70TYK20.61982807
71PRKAA10.61965114
72DDR20.61184128
73SMG10.59527599
74DYRK1B0.59410822
75ICK0.59324571
76PDGFRA0.57169944
77CSK0.56105867
78RET0.50656912
79LRRK20.50063465
80PDK20.49828852
81IRAK10.49229884
82JAK10.48952805
83CAMK2G0.48198599
84ZAP700.47025305
85CSF1R0.46899129
86GSK3A0.46284352
87DMPK0.44980373
88PDK10.44801198
89PDK40.44088844
90PDK30.44088844
91TTK0.43787878
92PRKACG0.41940731
93FYN0.41028224
94PIK3CG0.40424281
95ABL20.40391605
96NEK10.38514938
97JAK20.38113002
98PRKCA0.38077695
99PRKCZ0.37871973
100MAP3K140.37392630
101PAK30.37109664
102SGK30.35385038
103CAMK2D0.34888199
104PBK0.34682743
105RIPK40.34580633
106PIM10.33664245
107YES10.33357169
108MAP2K40.32388523
109GRK10.31581618
110RPS6KA20.30046437
111PRKCQ0.29238201
112CDK190.28358948
113KDR0.27522044
114MAPK40.27184544
115SRC0.26380302
116CDK60.25858259
117IRAK30.25703646
118BTK0.24154253
119CAMK2B0.23897395
120DAPK20.22969190
121MAPK70.22926580
122BMPR20.22853660
123ITK0.22637490
124IKBKE0.21768247
125JAK30.21481777
126IGF1R0.21425856
127MAPKAPK20.20976254
128LYN0.20615074
129CSNK1A10.20251104
130EEF2K0.20205601
131PRKCD0.18483982
132ROCK10.18346990
133MAPK150.16238114

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049753.41700370
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.32660793
3Sulfur metabolism_Homo sapiens_hsa009202.95195543
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.51404617
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.48814674
6Vitamin digestion and absorption_Homo sapiens_hsa049772.48693578
7Tryptophan metabolism_Homo sapiens_hsa003802.46823755
8Nitrogen metabolism_Homo sapiens_hsa009102.39400010
9Bile secretion_Homo sapiens_hsa049762.30663910
10Pentose and glucuronate interconversions_Homo sapiens_hsa000402.28774744
11Arginine biosynthesis_Homo sapiens_hsa002202.27641636
12Mineral absorption_Homo sapiens_hsa049782.27439478
13Caffeine metabolism_Homo sapiens_hsa002322.27123727
14Fatty acid degradation_Homo sapiens_hsa000712.19789636
15Histidine metabolism_Homo sapiens_hsa003402.15514810
16Renin-angiotensin system_Homo sapiens_hsa046142.07232408
17Starch and sucrose metabolism_Homo sapiens_hsa005002.06497510
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.03561320
19Butanoate metabolism_Homo sapiens_hsa006501.96876099
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.96550255
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.91525970
22PPAR signaling pathway_Homo sapiens_hsa033201.90162943
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.84660126
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.82306299
25Folate biosynthesis_Homo sapiens_hsa007901.76254800
26Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.75767470
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.65744477
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.64485469
29Peroxisome_Homo sapiens_hsa041461.57942657
30Galactose metabolism_Homo sapiens_hsa000521.55783939
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.53745270
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52705648
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.50244972
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.49318875
35Pyruvate metabolism_Homo sapiens_hsa006201.46495604
36Chemical carcinogenesis_Homo sapiens_hsa052041.46128397
37Propanoate metabolism_Homo sapiens_hsa006401.44780526
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.44431404
39beta-Alanine metabolism_Homo sapiens_hsa004101.43047054
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.40689693
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.34674719
42Fatty acid metabolism_Homo sapiens_hsa012121.33119673
43Glutathione metabolism_Homo sapiens_hsa004801.29155883
44Fructose and mannose metabolism_Homo sapiens_hsa000511.27337684
45Retinol metabolism_Homo sapiens_hsa008301.22847926
46Carbon metabolism_Homo sapiens_hsa012001.19392592
47Carbohydrate digestion and absorption_Homo sapiens_hsa049731.16932607
48Arginine and proline metabolism_Homo sapiens_hsa003301.15136550
49Glycerolipid metabolism_Homo sapiens_hsa005611.14895509
50Complement and coagulation cascades_Homo sapiens_hsa046101.14831940
51Protein digestion and absorption_Homo sapiens_hsa049741.12376290
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.11470608
53Selenocompound metabolism_Homo sapiens_hsa004501.10480436
54ABC transporters_Homo sapiens_hsa020101.07351583
55Asthma_Homo sapiens_hsa053101.05521893
56Phenylalanine metabolism_Homo sapiens_hsa003601.01781248
57Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00945932
58Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.00523179
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96053678
60Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.90242561
61Biosynthesis of amino acids_Homo sapiens_hsa012300.87066290
62Steroid biosynthesis_Homo sapiens_hsa001000.78861725
63Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78790056
64Tyrosine metabolism_Homo sapiens_hsa003500.78559327
65Allograft rejection_Homo sapiens_hsa053300.77270395
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.76972473
67Pentose phosphate pathway_Homo sapiens_hsa000300.74952871
68Autoimmune thyroid disease_Homo sapiens_hsa053200.71560613
69Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70373753
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.69517027
71Graft-versus-host disease_Homo sapiens_hsa053320.67355533
72Fatty acid elongation_Homo sapiens_hsa000620.66421472
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64947432
74Sulfur relay system_Homo sapiens_hsa041220.63129432
75Lysine degradation_Homo sapiens_hsa003100.62464825
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55213536
77Staphylococcus aureus infection_Homo sapiens_hsa051500.53626932
78Type I diabetes mellitus_Homo sapiens_hsa049400.49095289
79Metabolic pathways_Homo sapiens_hsa011000.47644331
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47305976
81Linoleic acid metabolism_Homo sapiens_hsa005910.44533587
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.42756114
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40119399
84Renin secretion_Homo sapiens_hsa049240.34143104
85Thyroid hormone synthesis_Homo sapiens_hsa049180.33984820
86Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.33206528
87Antigen processing and presentation_Homo sapiens_hsa046120.31210276
88Sphingolipid metabolism_Homo sapiens_hsa006000.29768369
89Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.28765559
90Pertussis_Homo sapiens_hsa051330.27435161
91Leishmaniasis_Homo sapiens_hsa051400.26422797
92Arachidonic acid metabolism_Homo sapiens_hsa005900.23782411
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22458878
94Glucagon signaling pathway_Homo sapiens_hsa049220.21449460
95Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.18843152
96Fatty acid biosynthesis_Homo sapiens_hsa000610.18255993
97Tight junction_Homo sapiens_hsa045300.16434779
98Insulin resistance_Homo sapiens_hsa049310.16355840
99Cocaine addiction_Homo sapiens_hsa050300.15559348
100Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.14209814
101Pancreatic secretion_Homo sapiens_hsa049720.13279903
102Hepatitis C_Homo sapiens_hsa051600.11117230
103Viral myocarditis_Homo sapiens_hsa054160.10500635
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.09454688
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.07693900
106Insulin secretion_Homo sapiens_hsa049110.07129799
107Bladder cancer_Homo sapiens_hsa052190.05236995
108Toxoplasmosis_Homo sapiens_hsa051450.05104672
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.03554900
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.00258772
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.0763652
112AMPK signaling pathway_Homo sapiens_hsa04152-0.0668612
113Thyroid cancer_Homo sapiens_hsa05216-0.0657236
114Type II diabetes mellitus_Homo sapiens_hsa04930-0.0583113
115Other glycan degradation_Homo sapiens_hsa00511-0.0504160
116Leukocyte transendothelial migration_Homo sapiens_hsa04670-0.0503247
117Ether lipid metabolism_Homo sapiens_hsa00565-0.0168898
118African trypanosomiasis_Homo sapiens_hsa05143-0.0020066

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