Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 6.56784761 |
2 | nuclear pore organization (GO:0006999) | 5.82994819 |
3 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 5.28203381 |
4 | protein localization to kinetochore (GO:0034501) | 4.97878855 |
5 | pore complex assembly (GO:0046931) | 4.97435485 |
6 | daunorubicin metabolic process (GO:0044597) | 4.80113138 |
7 | polyketide metabolic process (GO:0030638) | 4.80113138 |
8 | doxorubicin metabolic process (GO:0044598) | 4.80113138 |
9 | histone H4-K12 acetylation (GO:0043983) | 4.61436715 |
10 | pre-miRNA processing (GO:0031054) | 4.60673067 |
11 | regulation of nucleobase-containing compound transport (GO:0032239) | 4.52158469 |
12 | heterochromatin organization (GO:0070828) | 4.36510027 |
13 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 4.35339415 |
14 | regulation of telomere maintenance via telomerase (GO:0032210) | 4.29622936 |
15 | mitotic sister chromatid segregation (GO:0000070) | 4.27722554 |
16 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 4.26687744 |
17 | chromatin assembly (GO:0031497) | 4.22684478 |
18 | protein localization to chromosome, centromeric region (GO:0071459) | 4.14836632 |
19 | sister chromatid segregation (GO:0000819) | 4.10393800 |
20 | histone H4-K5 acetylation (GO:0043981) | 4.08889886 |
21 | histone H4-K8 acetylation (GO:0043982) | 4.08889886 |
22 | DNA unwinding involved in DNA replication (GO:0006268) | 4.00600554 |
23 | regulation of histone H3-K27 methylation (GO:0061085) | 3.93392652 |
24 | histone H3-K4 methylation (GO:0051568) | 3.83719264 |
25 | maintenance of protein location in nucleus (GO:0051457) | 3.79818626 |
26 | negative regulation of cell cycle G2/M phase transition (GO:1902750) | 3.77499836 |
27 | mitotic chromosome condensation (GO:0007076) | 3.77108094 |
28 | mitotic sister chromatid cohesion (GO:0007064) | 3.75320287 |
29 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.66291138 |
30 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.64572058 |
31 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.64572058 |
32 | positive regulation of protein import into nucleus, translocation (GO:0033160) | 3.61117896 |
33 | RNA stabilization (GO:0043489) | 3.59172729 |
34 | mRNA stabilization (GO:0048255) | 3.59172729 |
35 | histone H4-K16 acetylation (GO:0043984) | 3.58631919 |
36 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.54185038 |
37 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.50875679 |
38 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.50429303 |
39 | somite rostral/caudal axis specification (GO:0032525) | 3.49815435 |
40 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 3.48794023 |
41 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.48491898 |
42 | regulation of gene silencing by miRNA (GO:0060964) | 3.48491898 |
43 | regulation of gene silencing by RNA (GO:0060966) | 3.48491898 |
44 | regulation of histone H3-K9 methylation (GO:0051570) | 3.41327079 |
45 | NLS-bearing protein import into nucleus (GO:0006607) | 3.40710444 |
46 | notochord development (GO:0030903) | 3.39055947 |
47 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.37085200 |
48 | histone H3-K4 trimethylation (GO:0080182) | 3.35936939 |
49 | negative regulation of DNA repair (GO:0045738) | 3.35650789 |
50 | DNA duplex unwinding (GO:0032508) | 3.35208237 |
51 | DNA geometric change (GO:0032392) | 3.33997790 |
52 | negative regulation of histone methylation (GO:0031061) | 3.31834916 |
53 | positive regulation of chromosome segregation (GO:0051984) | 3.31829503 |
54 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.31394030 |
55 | negative regulation of epidermis development (GO:0045683) | 3.30643224 |
56 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.30331899 |
57 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.26611971 |
58 | mitotic nuclear envelope disassembly (GO:0007077) | 3.24708414 |
59 | positive regulation of keratinocyte differentiation (GO:0045618) | 3.23961302 |
60 | RNA localization (GO:0006403) | 3.21191779 |
61 | histone lysine demethylation (GO:0070076) | 3.20689433 |
62 | regulation of histone methylation (GO:0031060) | 3.20436316 |
63 | DNA replication checkpoint (GO:0000076) | 3.16579137 |
64 | histone H3-K9 demethylation (GO:0033169) | 3.15020041 |
65 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.14423594 |
66 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 3.12084714 |
67 | histone demethylation (GO:0016577) | 3.10483456 |
68 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.09864423 |
69 | embryonic process involved in female pregnancy (GO:0060136) | 3.08882726 |
70 | regulation of telomere maintenance (GO:0032204) | 3.08852108 |
71 | muscle organ morphogenesis (GO:0048644) | 3.07269844 |
72 | corticosteroid receptor signaling pathway (GO:0031958) | 3.06953796 |
73 | regulation of RNA export from nucleus (GO:0046831) | 3.05686997 |
74 | DNA topological change (GO:0006265) | 3.04390581 |
75 | negative regulation of telomerase activity (GO:0051974) | 3.04109079 |
76 | interferon-gamma production (GO:0032609) | 3.03282757 |
77 | membrane disassembly (GO:0030397) | 3.03136519 |
78 | nuclear envelope disassembly (GO:0051081) | 3.03136519 |
79 | positive regulation by host of viral transcription (GO:0043923) | 2.97786258 |
80 | regulation of response to osmotic stress (GO:0047484) | 2.97606316 |
81 | regulation of double-strand break repair (GO:2000779) | 2.97578579 |
82 | intestinal epithelial cell development (GO:0060576) | 2.95825945 |
83 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.95301339 |
84 | regulation of DNA-dependent DNA replication (GO:0090329) | 2.92536975 |
85 | regulation of gene silencing (GO:0060968) | 2.92453184 |
86 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.92275906 |
87 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.88828533 |
88 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.88828533 |
89 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.88828533 |
90 | response to epidermal growth factor (GO:0070849) | 2.88519405 |
91 | N-terminal protein amino acid acetylation (GO:0006474) | 2.88461111 |
92 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.87702618 |
93 | meiotic chromosome segregation (GO:0045132) | 2.87642003 |
94 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771) | 2.87586117 |
95 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.86880048 |
96 | trophectodermal cell differentiation (GO:0001829) | 2.86571202 |
97 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 2.85612583 |
98 | rRNA transcription (GO:0009303) | 2.84477587 |
99 | spindle assembly (GO:0051225) | 2.83586621 |
100 | chromatin assembly or disassembly (GO:0006333) | 2.83491847 |
101 | negative regulation of histone modification (GO:0031057) | 2.83006461 |
102 | interkinetic nuclear migration (GO:0022027) | 2.80243980 |
103 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.79923967 |
104 | definitive hemopoiesis (GO:0060216) | 2.78889437 |
105 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.77201951 |
106 | DNA conformation change (GO:0071103) | 2.76526024 |
107 | DNA packaging (GO:0006323) | 2.76422925 |
108 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.76324975 |
109 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.76324975 |
110 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.76324975 |
111 | protein export from nucleus (GO:0006611) | 2.74086099 |
112 | peptidyl-lysine dimethylation (GO:0018027) | 2.73014018 |
113 | histone phosphorylation (GO:0016572) | 2.72030874 |
114 | paraxial mesoderm development (GO:0048339) | 2.71753074 |
115 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 2.71504223 |
116 | protein localization to chromosome (GO:0034502) | 2.67816745 |
117 | protein dealkylation (GO:0008214) | 2.67612207 |
118 | protein demethylation (GO:0006482) | 2.67612207 |
119 | sister chromatid cohesion (GO:0007062) | 2.67199347 |
120 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.67175619 |
121 | regulation of chromatin silencing (GO:0031935) | 2.67169594 |
122 | response to UV-C (GO:0010225) | 2.66813257 |
123 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 2.66434538 |
124 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.65756327 |
125 | nuclear envelope organization (GO:0006998) | 2.64458073 |
126 | DNA replication initiation (GO:0006270) | 2.64327219 |
127 | mitotic metaphase plate congression (GO:0007080) | 2.64197428 |
128 | regulation of DNA damage checkpoint (GO:2000001) | 2.61804618 |
129 | histone H3 acetylation (GO:0043966) | 2.61793636 |
130 | DNA synthesis involved in DNA repair (GO:0000731) | 2.61391196 |
131 | mRNA transport (GO:0051028) | 2.61080392 |
132 | histone lysine methylation (GO:0034968) | 2.60875539 |
133 | peptidyl-lysine trimethylation (GO:0018023) | 2.60854476 |
134 | nucleus organization (GO:0006997) | 2.60344352 |
135 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.59970025 |
136 | kinetochore organization (GO:0051383) | 2.59312296 |
137 | histone H3-K36 demethylation (GO:0070544) | 2.57445346 |
138 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.56773470 |
139 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.56553613 |
140 | mammary gland epithelial cell proliferation (GO:0033598) | 2.55108202 |
141 | negative regulation of chromatin modification (GO:1903309) | 2.55103783 |
142 | megakaryocyte development (GO:0035855) | 2.54524853 |
143 | negative regulation of epidermal cell differentiation (GO:0045605) | 2.54360723 |
144 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.53792657 |
145 | regulation of translation in response to stress (GO:0043555) | 2.53695524 |
146 | regulation of histone H3-K4 methylation (GO:0051569) | 2.53592695 |
147 | primitive streak formation (GO:0090009) | 2.53513715 |
148 | regulation of protein polyubiquitination (GO:1902914) | 2.53039090 |
149 | chromosome condensation (GO:0030261) | 2.52517161 |
150 | positive regulation of histone deacetylation (GO:0031065) | 2.52184057 |
151 | histone methylation (GO:0016571) | 2.51534264 |
152 | regulation of sister chromatid cohesion (GO:0007063) | 2.51417147 |
153 | regulation of DNA endoreduplication (GO:0032875) | 2.51042517 |
154 | stress granule assembly (GO:0034063) | 2.51005161 |
155 | dosage compensation (GO:0007549) | 2.50935420 |
156 | protein K48-linked deubiquitination (GO:0071108) | 2.50730282 |
157 | peptidyl-lysine methylation (GO:0018022) | 2.49466748 |
158 | erythrocyte development (GO:0048821) | 2.48123183 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.67236870 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.76727222 |
3 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 4.66196358 |
4 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 4.66196358 |
5 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 4.66196358 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.95167578 |
7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.94753013 |
8 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 3.60966999 |
9 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.15872609 |
10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.90821457 |
11 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.75780929 |
12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.72778051 |
13 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.62773678 |
14 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 2.25814130 |
15 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.25451781 |
16 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 2.12439659 |
17 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 2.00497538 |
18 | MYC_22102868_ChIP-Seq_BL_Human | 1.94187800 |
19 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.93050468 |
20 | GATA1_22025678_ChIP-Seq_K562_Human | 1.85422441 |
21 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.80244907 |
22 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.79150467 |
23 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.78556328 |
24 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.74773790 |
25 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.73342733 |
26 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.70400381 |
27 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.70324454 |
28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.68373079 |
29 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.67469035 |
30 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.66538279 |
31 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.64187956 |
32 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.63770872 |
33 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.55481818 |
34 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.54428240 |
35 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.54056454 |
36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.52259664 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.51655329 |
38 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.49137505 |
39 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.48615310 |
40 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.45040506 |
41 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.44908871 |
42 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.44407324 |
43 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.44134763 |
44 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 1.42898777 |
45 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.42218188 |
46 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.39949677 |
47 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.39941870 |
48 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.37320516 |
49 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.37298512 |
50 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.36769821 |
51 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.36725092 |
52 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.36181997 |
53 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.31659293 |
54 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.31658093 |
55 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.31381857 |
56 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.30053983 |
57 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.29432137 |
58 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.29220510 |
59 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.29079967 |
60 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.28545144 |
61 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.27923297 |
62 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.24966061 |
63 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.24636131 |
64 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.23746528 |
65 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.21647688 |
66 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.21354955 |
67 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21041452 |
68 | * MAF_26560356_Chip-Seq_TH1_Human | 1.20929177 |
69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20878611 |
70 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.19569772 |
71 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.18698492 |
72 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.18683566 |
73 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 1.17878444 |
74 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16520154 |
75 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.16321103 |
76 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.15097442 |
77 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.14118126 |
78 | MYB_26560356_Chip-Seq_TH1_Human | 1.12161563 |
79 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.11711501 |
80 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.11202784 |
81 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.11202784 |
82 | PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 1.09863589 |
83 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.09674839 |
84 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.09593035 |
85 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.08449228 |
86 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.08302465 |
87 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.08205002 |
88 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07362457 |
89 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.06318972 |
90 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.06052265 |
91 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.05946700 |
92 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.05180862 |
93 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.05136358 |
94 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.05114425 |
95 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.04889070 |
96 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.04760666 |
97 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.03696924 |
98 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.02294168 |
99 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.01734962 |
100 | ATF3_27146783_Chip-Seq_COLON_Human | 1.00344843 |
101 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.00313121 |
102 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.00264318 |
103 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.99089208 |
104 | UTX_26944678_Chip-Seq_JUKART_Human | 0.98723376 |
105 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.98534665 |
106 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.97815434 |
107 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.97584337 |
108 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97438207 |
109 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96057554 |
110 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.96015054 |
111 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.95282996 |
112 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.94948278 |
113 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.94208864 |
114 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.94099256 |
115 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.93854793 |
116 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.93835872 |
117 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.93810205 |
118 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.93148234 |
119 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.92545071 |
120 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.91882769 |
121 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.91600978 |
122 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.91596207 |
123 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.91008813 |
124 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.90630013 |
125 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.90494956 |
126 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.90178728 |
127 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.90003974 |
128 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.89942119 |
129 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.89589764 |
130 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88174903 |
131 | POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 0.87726660 |
132 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.87176411 |
133 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.86978607 |
134 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.86976114 |
135 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.86279899 |
136 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.86178438 |
137 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.84920254 |
138 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.82679622 |
139 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.82526321 |
140 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.82392881 |
141 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.81530708 |
142 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.79638004 |
143 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.78633930 |
144 | * MYB_26560356_Chip-Seq_TH2_Human | 0.77576706 |
145 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.77175174 |
146 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.76885269 |
147 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.75850305 |
148 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.73974066 |
149 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.72256180 |
150 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.71516452 |
151 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.71333380 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 4.51156806 |
2 | MP0004264_abnormal_extraembryonic_tissu | 3.14389291 |
3 | MP0003890_abnormal_embryonic-extraembry | 2.86920954 |
4 | MP0002009_preneoplasia | 2.81618101 |
5 | MP0010352_gastrointestinal_tract_polyps | 2.71005036 |
6 | MP0002254_reproductive_system_inflammat | 2.56600314 |
7 | MP0010094_abnormal_chromosome_stability | 2.53470588 |
8 | MP0004957_abnormal_blastocyst_morpholog | 2.48012456 |
9 | MP0003111_abnormal_nucleus_morphology | 2.46615417 |
10 | MP0003077_abnormal_cell_cycle | 2.46381039 |
11 | MP0006292_abnormal_olfactory_placode | 2.31663367 |
12 | MP0003121_genomic_imprinting | 2.31316254 |
13 | MP0003705_abnormal_hypodermis_morpholog | 2.28533443 |
14 | MP0005451_abnormal_body_composition | 2.19826210 |
15 | MP0002396_abnormal_hematopoietic_system | 1.99547654 |
16 | MP0005380_embryogenesis_phenotype | 1.97472927 |
17 | MP0001672_abnormal_embryogenesis/_devel | 1.97472927 |
18 | MP0003787_abnormal_imprinting | 1.97466279 |
19 | MP0000569_abnormal_digit_pigmentation | 1.92087512 |
20 | MP0000350_abnormal_cell_proliferation | 1.90148851 |
21 | MP0004233_abnormal_muscle_weight | 1.87088495 |
22 | MP0003693_abnormal_embryo_hatching | 1.85700108 |
23 | MP0003984_embryonic_growth_retardation | 1.85364195 |
24 | MP0002088_abnormal_embryonic_growth/wei | 1.84498332 |
25 | MP0001293_anophthalmia | 1.79740478 |
26 | MP0002166_altered_tumor_susceptibility | 1.78214893 |
27 | MP0005409_darkened_coat_color | 1.76781200 |
28 | MP0005076_abnormal_cell_differentiation | 1.72805763 |
29 | MP0005257_abnormal_intraocular_pressure | 1.72130725 |
30 | MP0002086_abnormal_extraembryonic_tissu | 1.69077275 |
31 | MP0008007_abnormal_cellular_replicative | 1.66613838 |
32 | MP0010307_abnormal_tumor_latency | 1.66054549 |
33 | MP0008058_abnormal_DNA_repair | 1.63617638 |
34 | MP0003943_abnormal_hepatobiliary_system | 1.59388032 |
35 | MP0005075_abnormal_melanosome_morpholog | 1.57165076 |
36 | MP0002084_abnormal_developmental_patter | 1.56156721 |
37 | MP0003011_delayed_dark_adaptation | 1.55409301 |
38 | MP0002085_abnormal_embryonic_tissue | 1.50146694 |
39 | MP0004197_abnormal_fetal_growth/weight/ | 1.49283716 |
40 | MP0003123_paternal_imprinting | 1.46425775 |
41 | MP0001849_ear_inflammation | 1.46072521 |
42 | MP0005394_taste/olfaction_phenotype | 1.44309838 |
43 | MP0005499_abnormal_olfactory_system | 1.44309838 |
44 | MP0001730_embryonic_growth_arrest | 1.44116932 |
45 | MP0003300_gastrointestinal_ulcer | 1.41359488 |
46 | MP0010234_abnormal_vibrissa_follicle | 1.39739851 |
47 | MP0002277_abnormal_respiratory_mucosa | 1.38111784 |
48 | MP0000490_abnormal_crypts_of | 1.37568707 |
49 | MP0003091_abnormal_cell_migration | 1.35553581 |
50 | MP0002092_abnormal_eye_morphology | 1.34506412 |
51 | MP0002006_tumorigenesis | 1.33398253 |
52 | MP0000432_abnormal_head_morphology | 1.32121496 |
53 | MP0001697_abnormal_embryo_size | 1.25345872 |
54 | MP0008877_abnormal_DNA_methylation | 1.22066612 |
55 | MP0004808_abnormal_hematopoietic_stem | 1.20626407 |
56 | MP0003937_abnormal_limbs/digits/tail_de | 1.20270126 |
57 | MP0002796_impaired_skin_barrier | 1.19320190 |
58 | MP0003935_abnormal_craniofacial_develop | 1.18422849 |
59 | MP0009697_abnormal_copulation | 1.17581770 |
60 | MP0009672_abnormal_birth_weight | 1.17120498 |
61 | MP0003656_abnormal_erythrocyte_physiolo | 1.15240556 |
62 | MP0009703_decreased_birth_body | 1.12279144 |
63 | MP0002925_abnormal_cardiovascular_devel | 1.09073443 |
64 | MP0002332_abnormal_exercise_endurance | 1.07995198 |
65 | MP0008932_abnormal_embryonic_tissue | 1.07645223 |
66 | MP0000313_abnormal_cell_death | 1.07278847 |
67 | MP0003122_maternal_imprinting | 1.06890093 |
68 | MP0002653_abnormal_ependyma_morphology | 1.05219129 |
69 | MP0000428_abnormal_craniofacial_morphol | 1.04687198 |
70 | MP0005248_abnormal_Harderian_gland | 1.03606379 |
71 | MP0010030_abnormal_orbit_morphology | 1.02711833 |
72 | MP0003718_maternal_effect | 1.02109040 |
73 | MP0002080_prenatal_lethality | 1.01423217 |
74 | MP0003566_abnormal_cell_adhesion | 1.00997578 |
75 | MP0008961_abnormal_basal_metabolism | 1.00726696 |
76 | MP0002098_abnormal_vibrissa_morphology | 0.99191704 |
77 | MP0002877_abnormal_melanocyte_morpholog | 0.98014971 |
78 | MP0003755_abnormal_palate_morphology | 0.97550704 |
79 | MP0000383_abnormal_hair_follicle | 0.95112140 |
80 | MP0010630_abnormal_cardiac_muscle | 0.94520682 |
81 | MP0001661_extended_life_span | 0.94269620 |
82 | MP0003786_premature_aging | 0.93775330 |
83 | MP0002233_abnormal_nose_morphology | 0.93527487 |
84 | MP0003115_abnormal_respiratory_system | 0.93256194 |
85 | MP0001216_abnormal_epidermal_layer | 0.92366794 |
86 | MP0003119_abnormal_digestive_system | 0.92158564 |
87 | MP0000703_abnormal_thymus_morphology | 0.91956058 |
88 | MP0009278_abnormal_bone_marrow | 0.91847344 |
89 | MP0004947_skin_inflammation | 0.91642087 |
90 | MP0003448_altered_tumor_morphology | 0.90561803 |
91 | MP0005023_abnormal_wound_healing | 0.90478346 |
92 | MP0002697_abnormal_eye_size | 0.90105799 |
93 | MP0000733_abnormal_muscle_development | 0.89534466 |
94 | MP0010678_abnormal_skin_adnexa | 0.88811581 |
95 | MP0003938_abnormal_ear_development | 0.88007220 |
96 | MP0009115_abnormal_fat_cell | 0.87899512 |
97 | MP0002932_abnormal_joint_morphology | 0.87684033 |
98 | MP0005384_cellular_phenotype | 0.87033728 |
99 | MP0002398_abnormal_bone_marrow | 0.87021237 |
100 | MP0002019_abnormal_tumor_incidence | 0.86642109 |
101 | MP0001286_abnormal_eye_development | 0.86537391 |
102 | MP0002132_abnormal_respiratory_system | 0.86405471 |
103 | MP0005501_abnormal_skin_physiology | 0.86069060 |
104 | MP0001873_stomach_inflammation | 0.84027108 |
105 | MP0003828_pulmonary_edema | 0.83092842 |
106 | MP0004185_abnormal_adipocyte_glucose | 0.82710902 |
107 | MP0001915_intracranial_hemorrhage | 0.82665686 |
108 | MP0002089_abnormal_postnatal_growth/wei | 0.82418838 |
109 | MP0003183_abnormal_peptide_metabolism | 0.81843484 |
110 | MP0001800_abnormal_humoral_immune | 0.80799896 |
111 | MP0000003_abnormal_adipose_tissue | 0.80361527 |
112 | MP0005310_abnormal_salivary_gland | 0.80230738 |
113 | MP0002127_abnormal_cardiovascular_syste | 0.79714303 |
114 | MP0002114_abnormal_axial_skeleton | 0.79342366 |
115 | MP0004381_abnormal_hair_follicle | 0.79281348 |
116 | MP0003453_abnormal_keratinocyte_physiol | 0.77533453 |
117 | MP0002722_abnormal_immune_system | 0.77264077 |
118 | MP0000516_abnormal_urinary_system | 0.77005414 |
119 | MP0005367_renal/urinary_system_phenotyp | 0.77005414 |
120 | MP0003699_abnormal_female_reproductive | 0.76715654 |
121 | MP0008770_decreased_survivor_rate | 0.75438658 |
122 | MP0001835_abnormal_antigen_presentation | 0.74256084 |
123 | MP0004858_abnormal_nervous_system | 0.73967079 |
124 | MP0003763_abnormal_thymus_physiology | 0.73857217 |
125 | MP0000627_abnormal_mammary_gland | 0.73809169 |
126 | MP0000377_abnormal_hair_follicle | 0.73404167 |
127 | MP0000689_abnormal_spleen_morphology | 0.72954460 |
128 | MP0003315_abnormal_perineum_morphology | 0.72464929 |
129 | MP0009333_abnormal_splenocyte_physiolog | 0.72442061 |
130 | MP0000049_abnormal_middle_ear | 0.72358051 |
131 | MP0003941_abnormal_skin_development | 0.72093343 |
132 | MP0005621_abnormal_cell_physiology | 0.72016110 |
133 | MP0001881_abnormal_mammary_gland | 0.71875384 |
134 | MP0000858_altered_metastatic_potential | 0.71583662 |
135 | MP0005397_hematopoietic_system_phenotyp | 0.71493200 |
136 | MP0001545_abnormal_hematopoietic_system | 0.71493200 |
137 | MP0005666_abnormal_adipose_tissue | 0.71362158 |
138 | MP0002116_abnormal_craniofacial_bone | 0.70648273 |
139 | MP0002429_abnormal_blood_cell | 0.69276877 |
140 | MP0005375_adipose_tissue_phenotype | 0.68518412 |
141 | MP0001270_distended_abdomen | 0.68464190 |
142 | MP0009931_abnormal_skin_appearance | 0.68257636 |
143 | MP0001851_eye_inflammation | 0.67910850 |
144 | MP0003868_abnormal_feces_composition | 0.65446343 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hypochromic microcytic anemia (HP:0004840) | 4.67377060 |
2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.56057627 |
3 | Chromsome breakage (HP:0040012) | 4.46541976 |
4 | Bilateral microphthalmos (HP:0007633) | 3.99581135 |
5 | Ependymoma (HP:0002888) | 3.67522122 |
6 | Rib fusion (HP:0000902) | 3.65686857 |
7 | Rhabdomyosarcoma (HP:0002859) | 3.25561495 |
8 | Volvulus (HP:0002580) | 3.18365796 |
9 | Flat acetabular roof (HP:0003180) | 3.16567007 |
10 | Acute myeloid leukemia (HP:0004808) | 3.15405080 |
11 | Deep philtrum (HP:0002002) | 3.12412157 |
12 | Sparse lateral eyebrow (HP:0005338) | 3.12084654 |
13 | Neoplasm of striated muscle (HP:0009728) | 3.10359971 |
14 | Hepatoblastoma (HP:0002884) | 3.04646296 |
15 | Birth length less than 3rd percentile (HP:0003561) | 3.00169284 |
16 | Dysmetric saccades (HP:0000641) | 2.98047699 |
17 | Astrocytoma (HP:0009592) | 2.97984013 |
18 | Abnormality of the astrocytes (HP:0100707) | 2.97984013 |
19 | Intestinal fistula (HP:0100819) | 2.95473013 |
20 | Abnormality of the fingertips (HP:0001211) | 2.86779140 |
21 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.86195037 |
22 | Impulsivity (HP:0100710) | 2.81101118 |
23 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.78489477 |
24 | Acute lymphatic leukemia (HP:0006721) | 2.77777544 |
25 | Meckel diverticulum (HP:0002245) | 2.72483756 |
26 | Ectopic kidney (HP:0000086) | 2.58833672 |
27 | Narrow palate (HP:0000189) | 2.56679263 |
28 | Embryonal renal neoplasm (HP:0011794) | 2.56035984 |
29 | Abnormality of the ileum (HP:0001549) | 2.55662968 |
30 | Medulloblastoma (HP:0002885) | 2.55219876 |
31 | Rectal fistula (HP:0100590) | 2.52309719 |
32 | Rectovaginal fistula (HP:0000143) | 2.52309719 |
33 | Hyperacusis (HP:0010780) | 2.47749711 |
34 | Short humerus (HP:0005792) | 2.46530186 |
35 | Abnormality of chromosome stability (HP:0003220) | 2.46437089 |
36 | Glioma (HP:0009733) | 2.45586956 |
37 | Abnormality of the lower motor neuron (HP:0002366) | 2.44258831 |
38 | Prominent nose (HP:0000448) | 2.41686642 |
39 | Absent frontal sinuses (HP:0002688) | 2.41252084 |
40 | Low anterior hairline (HP:0000294) | 2.38824649 |
41 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.38549579 |
42 | Supernumerary ribs (HP:0005815) | 2.37287843 |
43 | Broad face (HP:0000283) | 2.37051447 |
44 | Sandal gap (HP:0001852) | 2.33696304 |
45 | Lip pit (HP:0100267) | 2.32238320 |
46 | Neonatal hypoglycemia (HP:0001998) | 2.31636401 |
47 | Large earlobe (HP:0009748) | 2.30198915 |
48 | Long eyelashes (HP:0000527) | 2.28314942 |
49 | Shawl scrotum (HP:0000049) | 2.27489860 |
50 | Neoplasm of the oral cavity (HP:0100649) | 2.27208439 |
51 | Overlapping toe (HP:0001845) | 2.26805744 |
52 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.25972500 |
53 | Fused cervical vertebrae (HP:0002949) | 2.24857897 |
54 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.19599726 |
55 | Asymmetry of the thorax (HP:0001555) | 2.18907946 |
56 | Heterotopia (HP:0002282) | 2.18055344 |
57 | Skin tags (HP:0010609) | 2.17904904 |
58 | Preauricular skin tag (HP:0000384) | 2.17824443 |
59 | Ankyloglossia (HP:0010296) | 2.17529099 |
60 | Abnormality of the columella (HP:0009929) | 2.16798617 |
61 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.16096240 |
62 | Hypochromic anemia (HP:0001931) | 2.15531354 |
63 | Supernumerary spleens (HP:0009799) | 2.13887005 |
64 | Abnormal lung lobation (HP:0002101) | 2.13735212 |
65 | Abnormal foot bone ossification (HP:0010675) | 2.12617991 |
66 | Relative macrocephaly (HP:0004482) | 2.11650273 |
67 | Abnormality of the preputium (HP:0100587) | 2.10835995 |
68 | Small intestinal stenosis (HP:0012848) | 2.10540916 |
69 | Duodenal stenosis (HP:0100867) | 2.10540916 |
70 | Obsessive-compulsive behavior (HP:0000722) | 2.09994517 |
71 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.09522775 |
72 | Subacute progressive viral hepatitis (HP:0006572) | 2.08888915 |
73 | Myelodysplasia (HP:0002863) | 2.08839944 |
74 | Septate vagina (HP:0001153) | 2.07584755 |
75 | Abnormality of chromosome segregation (HP:0002916) | 2.05762454 |
76 | Vaginal fistula (HP:0004320) | 2.04799221 |
77 | Capillary hemangiomas (HP:0005306) | 2.04228417 |
78 | Papillary thyroid carcinoma (HP:0002895) | 2.01937146 |
79 | Diastasis recti (HP:0001540) | 1.97341770 |
80 | Persistence of primary teeth (HP:0006335) | 1.97302074 |
81 | Broad thumb (HP:0011304) | 1.96913913 |
82 | 11 pairs of ribs (HP:0000878) | 1.95818474 |
83 | Abnormality of the labia minora (HP:0012880) | 1.94861836 |
84 | Preauricular pit (HP:0004467) | 1.93933506 |
85 | Periauricular skin pits (HP:0100277) | 1.93933506 |
86 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.92549332 |
87 | Abnormality of the salivary glands (HP:0010286) | 1.91935165 |
88 | Advanced eruption of teeth (HP:0006288) | 1.91666579 |
89 | Smooth philtrum (HP:0000319) | 1.90955238 |
90 | Short 5th finger (HP:0009237) | 1.89858800 |
91 | Increased nuchal translucency (HP:0010880) | 1.89824513 |
92 | Anal stenosis (HP:0002025) | 1.89745838 |
93 | Abnormality of the thoracic spine (HP:0100711) | 1.87634477 |
94 | Acanthocytosis (HP:0001927) | 1.86890822 |
95 | Deep palmar crease (HP:0006191) | 1.86358253 |
96 | Right ventricular cardiomyopathy (HP:0011663) | 1.86247219 |
97 | Dislocated radial head (HP:0003083) | 1.86193228 |
98 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.85506314 |
99 | Sloping forehead (HP:0000340) | 1.83934129 |
100 | Leiomyosarcoma (HP:0100243) | 1.83800758 |
101 | Uterine leiomyosarcoma (HP:0002891) | 1.83800758 |
102 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.83693754 |
103 | Gastrointestinal carcinoma (HP:0002672) | 1.83693754 |
104 | Underdeveloped nasal alae (HP:0000430) | 1.82644788 |
105 | Abnormal tarsal ossification (HP:0008369) | 1.82625055 |
106 | Renovascular hypertension (HP:0100817) | 1.81579882 |
107 | Hypopigmentation of the fundus (HP:0007894) | 1.79503820 |
108 | Skin pits (HP:0100276) | 1.79241689 |
109 | Vertebral fusion (HP:0002948) | 1.79065207 |
110 | Macroorchidism (HP:0000053) | 1.78466589 |
111 | Self-mutilation (HP:0000742) | 1.76860556 |
112 | Bifid tongue (HP:0010297) | 1.75625450 |
113 | Clubbing of toes (HP:0100760) | 1.75388385 |
114 | Cutis marmorata (HP:0000965) | 1.75007477 |
115 | Abnormality of the duodenum (HP:0002246) | 1.74492925 |
116 | Multiple enchondromatosis (HP:0005701) | 1.74285058 |
117 | Somatic mutation (HP:0001428) | 1.74278150 |
118 | Thick eyebrow (HP:0000574) | 1.74267148 |
119 | Deviation of the thumb (HP:0009603) | 1.73723925 |
120 | Missing ribs (HP:0000921) | 1.73539277 |
121 | Pseudobulbar signs (HP:0002200) | 1.72635145 |
122 | Abnormality of the radial head (HP:0003995) | 1.72282913 |
123 | Urethral obstruction (HP:0000796) | 1.72175424 |
124 | Wide nose (HP:0000445) | 1.72119359 |
125 | Combined immunodeficiency (HP:0005387) | 1.71494818 |
126 | Deep venous thrombosis (HP:0002625) | 1.71126869 |
127 | Abnormality of oral frenula (HP:0000190) | 1.70959718 |
128 | Premature skin wrinkling (HP:0100678) | 1.69321717 |
129 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.69156516 |
130 | Abnormality of the pubic bones (HP:0003172) | 1.68895220 |
131 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.68866994 |
132 | Proximal placement of thumb (HP:0009623) | 1.68619690 |
133 | Spinal cord lesions (HP:0100561) | 1.68567307 |
134 | Syringomyelia (HP:0003396) | 1.68567307 |
135 | Broad palm (HP:0001169) | 1.68331057 |
136 | Ulnar bowing (HP:0003031) | 1.68186511 |
137 | Poikiloderma (HP:0001029) | 1.67677430 |
138 | Abnormality of the carotid arteries (HP:0005344) | 1.67507881 |
139 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.66981145 |
140 | Limited elbow extension (HP:0001377) | 1.66636526 |
141 | Vertebral arch anomaly (HP:0008438) | 1.66549860 |
142 | Selective tooth agenesis (HP:0001592) | 1.66278643 |
143 | Hypoplastic scapulae (HP:0000882) | 1.65928720 |
144 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 1.65928720 |
145 | Abnormality of the nasal septum (HP:0000419) | 1.65828606 |
146 | Anomalous pulmonary venous return (HP:0010772) | 1.65772485 |
147 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.65566621 |
148 | Renal duplication (HP:0000075) | 1.65275090 |
149 | Cafe-au-lait spot (HP:0000957) | 1.64860382 |
150 | Truncal obesity (HP:0001956) | 1.64205006 |
151 | Short chin (HP:0000331) | 1.63755206 |
152 | Viral hepatitis (HP:0006562) | 1.62361068 |
153 | Facial hemangioma (HP:0000329) | 1.60295078 |
154 | Intestinal malrotation (HP:0002566) | 1.58976656 |
155 | Abnormality of homocysteine metabolism (HP:0010919) | 1.58935708 |
156 | Homocystinuria (HP:0002156) | 1.58935708 |
157 | Nasolacrimal duct obstruction (HP:0000579) | 1.58914926 |
158 | Thoracic kyphosis (HP:0002942) | 1.57194974 |
159 | Colitis (HP:0002583) | 1.55302051 |
160 | Abnormality of the lacrimal duct (HP:0011481) | 1.54319984 |
161 | Cubitus valgus (HP:0002967) | 1.53405293 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * CDK12 | 4.81505416 |
2 | TRIB3 | 2.91420282 |
3 | CDC7 | 2.87919255 |
4 | TTK | 2.83821870 |
5 | LATS1 | 2.76400961 |
6 | STK10 | 2.75209950 |
7 | GRK6 | 2.64369292 |
8 | ERN1 | 2.61052648 |
9 | BRD4 | 2.58261704 |
10 | GRK5 | 2.32354948 |
11 | SMG1 | 2.20945310 |
12 | CSF1R | 2.09201129 |
13 | FGFR4 | 2.06705335 |
14 | CHEK2 | 2.02646163 |
15 | TGFBR2 | 1.94601442 |
16 | NEK2 | 1.92884898 |
17 | EPHA2 | 1.79331664 |
18 | GRK1 | 1.71519182 |
19 | MAP3K10 | 1.69307284 |
20 | CAMK1D | 1.65555040 |
21 | FGFR3 | 1.64081713 |
22 | MAPK7 | 1.63849662 |
23 | STK3 | 1.60890723 |
24 | TYRO3 | 1.58565124 |
25 | WNK1 | 1.57636859 |
26 | ADRBK2 | 1.55349380 |
27 | CHEK1 | 1.54345430 |
28 | PLK1 | 1.46040289 |
29 | MTOR | 1.35488899 |
30 | SRPK1 | 1.33624147 |
31 | CHUK | 1.30562984 |
32 | CDK4 | 1.29318759 |
33 | STK4 | 1.27808476 |
34 | ATM | 1.26801871 |
35 | ATR | 1.24790713 |
36 | * CDK7 | 1.21828676 |
37 | MATK | 1.17600038 |
38 | ZAK | 1.13516006 |
39 | GRK7 | 1.13218391 |
40 | MST1R | 1.13084860 |
41 | PNCK | 1.09859945 |
42 | MELK | 1.09792771 |
43 | CAMK4 | 1.08132095 |
44 | AKT3 | 1.07931556 |
45 | MAPK11 | 1.05839848 |
46 | PIM1 | 1.05790390 |
47 | AURKB | 1.04572952 |
48 | MKNK2 | 1.04275964 |
49 | NLK | 0.98709631 |
50 | CDK2 | 0.98213537 |
51 | IRAK3 | 0.98080386 |
52 | BRSK2 | 0.97501497 |
53 | MARK2 | 0.95653714 |
54 | CDK6 | 0.94558881 |
55 | EIF2AK2 | 0.93154540 |
56 | CSK | 0.92285601 |
57 | CAMK1G | 0.92247812 |
58 | ALK | 0.91121816 |
59 | IKBKB | 0.88773467 |
60 | CDK9 | 0.88684689 |
61 | TSSK6 | 0.87461822 |
62 | HIPK2 | 0.85171806 |
63 | JAK3 | 0.84820184 |
64 | MAP2K3 | 0.83972764 |
65 | KSR2 | 0.83340358 |
66 | RIPK4 | 0.83301472 |
67 | TRPM7 | 0.83240400 |
68 | MAP3K14 | 0.83084984 |
69 | MAP3K2 | 0.82769001 |
70 | CDC42BPA | 0.82418004 |
71 | NUAK1 | 0.80867593 |
72 | SGK3 | 0.79513948 |
73 | RPS6KB2 | 0.78859626 |
74 | PKN2 | 0.77501120 |
75 | PLK4 | 0.76282135 |
76 | STK38L | 0.75422153 |
77 | MAP3K13 | 0.74417082 |
78 | MOS | 0.72306167 |
79 | IRAK1 | 0.71957015 |
80 | CDK1 | 0.70161278 |
81 | AKT2 | 0.69103250 |
82 | NEK9 | 0.67794606 |
83 | MAPK14 | 0.67305680 |
84 | MARK3 | 0.67118321 |
85 | RPS6KA4 | 0.66353207 |
86 | BMX | 0.65595061 |
87 | RET | 0.64921901 |
88 | SGK2 | 0.64877163 |
89 | PAK4 | 0.64566940 |
90 | EEF2K | 0.61448126 |
91 | MAP3K8 | 0.60624788 |
92 | MET | 0.60561897 |
93 | LATS2 | 0.59443832 |
94 | MKNK1 | 0.58767140 |
95 | RAF1 | 0.58682603 |
96 | TLK1 | 0.57956733 |
97 | STK24 | 0.57667179 |
98 | CDK3 | 0.57293558 |
99 | ITK | 0.56675370 |
100 | MAPK10 | 0.55989799 |
101 | PDGFRB | 0.55762616 |
102 | MAPK1 | 0.55011325 |
103 | MAP4K1 | 0.53112411 |
104 | YES1 | 0.52130184 |
105 | IRAK4 | 0.51926130 |
106 | AKT1 | 0.51754032 |
107 | GSK3B | 0.51567871 |
108 | ICK | 0.50742828 |
109 | TYK2 | 0.49932995 |
110 | MAP3K7 | 0.48127027 |
111 | CSNK1D | 0.47962729 |
112 | HCK | 0.47586045 |
113 | PRKG2 | 0.47427679 |
114 | DMPK | 0.47243180 |
115 | SCYL2 | 0.47091952 |
116 | SIK2 | 0.46039367 |
117 | MAP3K1 | 0.45010560 |
118 | PDGFRA | 0.44667159 |
119 | TAF1 | 0.43079954 |
120 | DYRK3 | 0.42208788 |
121 | EIF2AK1 | 0.42078621 |
122 | CSNK1E | 0.41669819 |
123 | NEK6 | 0.41242711 |
124 | RIPK1 | 0.41187247 |
125 | WEE1 | 0.41064129 |
126 | PRKAA2 | 0.40940173 |
127 | JAK1 | 0.40298863 |
128 | CLK1 | 0.37976916 |
129 | PAK2 | 0.37937246 |
130 | SIK1 | 0.37885934 |
131 | PASK | 0.37879075 |
132 | PRKDC | 0.37855777 |
133 | IGF1R | 0.36820658 |
134 | RPS6KA5 | 0.36476311 |
135 | PRKAA1 | 0.36167506 |
136 | PRPF4B | 0.35312464 |
137 | CDK8 | 0.35021777 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.11611391 |
2 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.38104783 |
3 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.16599993 |
4 | Cell cycle_Homo sapiens_hsa04110 | 2.12804818 |
5 | RNA transport_Homo sapiens_hsa03013 | 2.05455130 |
6 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.02631686 |
7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.80700340 |
8 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.74497724 |
9 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.74019068 |
10 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.73791469 |
11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.72795745 |
12 | Mismatch repair_Homo sapiens_hsa03430 | 1.72150034 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.70432253 |
14 | Homologous recombination_Homo sapiens_hsa03440 | 1.62975711 |
15 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.61599412 |
16 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.55361170 |
17 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.50293892 |
18 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.48954354 |
19 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.47579710 |
20 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.46414837 |
21 | Lysine degradation_Homo sapiens_hsa00310 | 1.45788539 |
22 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.42911550 |
23 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.39091315 |
24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.38664960 |
25 | RNA degradation_Homo sapiens_hsa03018 | 1.37769649 |
26 | Adherens junction_Homo sapiens_hsa04520 | 1.36812038 |
27 | DNA replication_Homo sapiens_hsa03030 | 1.36097383 |
28 | Spliceosome_Homo sapiens_hsa03040 | 1.32694127 |
29 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.31920355 |
30 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.27762016 |
31 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.27638008 |
32 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.25210429 |
33 | Base excision repair_Homo sapiens_hsa03410 | 1.20765865 |
34 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.19284785 |
35 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.15238199 |
36 | HTLV-I infection_Homo sapiens_hsa05166 | 1.13766646 |
37 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.13370939 |
38 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.11494710 |
39 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.07093158 |
40 | Influenza A_Homo sapiens_hsa05164 | 1.06667679 |
41 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.05950943 |
42 | Thyroid cancer_Homo sapiens_hsa05216 | 1.05922671 |
43 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.05498886 |
44 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.04908579 |
45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.04511871 |
46 | Measles_Homo sapiens_hsa05162 | 1.04225392 |
47 | Glioma_Homo sapiens_hsa05214 | 1.02705177 |
48 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.99702352 |
49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.97826036 |
50 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.97016455 |
51 | Insulin resistance_Homo sapiens_hsa04931 | 0.95771555 |
52 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.95555258 |
53 | Apoptosis_Homo sapiens_hsa04210 | 0.95458779 |
54 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.93387005 |
55 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.92328862 |
56 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.92150543 |
57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.91310516 |
58 | Pathways in cancer_Homo sapiens_hsa05200 | 0.91160384 |
59 | Leishmaniasis_Homo sapiens_hsa05140 | 0.90315376 |
60 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.90083681 |
61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.89519454 |
62 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.89459730 |
63 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.88822872 |
64 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.86955191 |
65 | Prostate cancer_Homo sapiens_hsa05215 | 0.86180392 |
66 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.84904560 |
67 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.84442186 |
68 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.83899160 |
69 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.83869819 |
70 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.83246487 |
71 | Colorectal cancer_Homo sapiens_hsa05210 | 0.82791663 |
72 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.81740940 |
73 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.81473443 |
74 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.81448914 |
75 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.80005529 |
76 | Hepatitis B_Homo sapiens_hsa05161 | 0.79468516 |
77 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.79112579 |
78 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.78473281 |
79 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.77854541 |
80 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.76151084 |
81 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.75385266 |
82 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.74231625 |
83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.73729409 |
84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.72140963 |
85 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.71744881 |
86 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68122795 |
87 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.68086205 |
88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.67953726 |
89 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.66558621 |
90 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.65853098 |
91 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.65771644 |
92 | Circadian rhythm_Homo sapiens_hsa04710 | 0.65278283 |
93 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.64844772 |
94 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.64135625 |
95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.63056021 |
96 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.61912917 |
97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61911597 |
98 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.60708746 |
99 | Platelet activation_Homo sapiens_hsa04611 | 0.60451808 |
100 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.58130348 |
101 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.57473825 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.53914068 |
103 | Melanoma_Homo sapiens_hsa05218 | 0.53654367 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.53124732 |
105 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.52464705 |
106 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.51542316 |
107 | Allograft rejection_Homo sapiens_hsa05330 | 0.50298815 |
108 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.50126208 |
109 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.49657428 |
110 | Focal adhesion_Homo sapiens_hsa04510 | 0.48774567 |
111 | Hepatitis C_Homo sapiens_hsa05160 | 0.48714630 |
112 | Legionellosis_Homo sapiens_hsa05134 | 0.48096555 |
113 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47913027 |
114 | Bladder cancer_Homo sapiens_hsa05219 | 0.47911138 |
115 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.47468414 |
116 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.47143987 |
117 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.47060781 |
118 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.46260613 |
119 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.46076207 |
120 | Malaria_Homo sapiens_hsa05144 | 0.45418616 |
121 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.45320044 |
122 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.45065476 |
123 | Other glycan degradation_Homo sapiens_hsa00511 | 0.44931137 |
124 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.43862819 |