Rank | Gene Set | Z-score |
---|---|---|
1 | cullin deneddylation (GO:0010388) | 5.96644769 |
2 | protein deneddylation (GO:0000338) | 5.54982089 |
3 | ribosomal small subunit assembly (GO:0000028) | 4.24811308 |
4 | behavioral response to nicotine (GO:0035095) | 3.81400735 |
5 | CENP-A containing nucleosome assembly (GO:0034080) | 3.64428698 |
6 | kinetochore organization (GO:0051383) | 3.50757193 |
7 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.43851661 |
8 | chromatin remodeling at centromere (GO:0031055) | 3.43258088 |
9 | response to pheromone (GO:0019236) | 3.41951825 |
10 | protein complex biogenesis (GO:0070271) | 3.40139983 |
11 | telomere maintenance via recombination (GO:0000722) | 3.38740704 |
12 | kinetochore assembly (GO:0051382) | 3.36941774 |
13 | platelet dense granule organization (GO:0060155) | 3.32520687 |
14 | daunorubicin metabolic process (GO:0044597) | 3.32003701 |
15 | polyketide metabolic process (GO:0030638) | 3.32003701 |
16 | doxorubicin metabolic process (GO:0044598) | 3.32003701 |
17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.30250482 |
18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.30250482 |
19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.30250482 |
20 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.28408217 |
21 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.24781252 |
22 | meiotic chromosome segregation (GO:0045132) | 3.23244976 |
23 | DNA ligation (GO:0006266) | 3.23122567 |
24 | respiratory chain complex IV assembly (GO:0008535) | 3.17949593 |
25 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.13681469 |
26 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.13681469 |
27 | mitotic recombination (GO:0006312) | 3.13572839 |
28 | centriole assembly (GO:0098534) | 3.09795303 |
29 | definitive hemopoiesis (GO:0060216) | 3.08192237 |
30 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.07559765 |
31 | neural tube formation (GO:0001841) | 3.06654752 |
32 | DNA deamination (GO:0045006) | 3.01470283 |
33 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.01358008 |
34 | proteasome assembly (GO:0043248) | 3.01315426 |
35 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.98994929 |
36 | reciprocal meiotic recombination (GO:0007131) | 2.95532668 |
37 | reciprocal DNA recombination (GO:0035825) | 2.95532668 |
38 | replication fork processing (GO:0031297) | 2.93206743 |
39 | cytochrome complex assembly (GO:0017004) | 2.92661859 |
40 | lymphoid progenitor cell differentiation (GO:0002320) | 2.91606730 |
41 | DNA demethylation (GO:0080111) | 2.90821038 |
42 | tRNA methylation (GO:0030488) | 2.89509628 |
43 | postreplication repair (GO:0006301) | 2.87893731 |
44 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.85336935 |
45 | indolalkylamine metabolic process (GO:0006586) | 2.84701355 |
46 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.84431866 |
47 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.83170378 |
48 | protein neddylation (GO:0045116) | 2.82317577 |
49 | magnesium ion transport (GO:0015693) | 2.80916966 |
50 | centriole replication (GO:0007099) | 2.80869138 |
51 | regulation of mitochondrial translation (GO:0070129) | 2.78639412 |
52 | synapsis (GO:0007129) | 2.78152355 |
53 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.76266198 |
54 | DNA replication-independent nucleosome organization (GO:0034724) | 2.76266198 |
55 | telomere maintenance (GO:0000723) | 2.76126936 |
56 | dendritic cell chemotaxis (GO:0002407) | 2.75729754 |
57 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.75408049 |
58 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.75408049 |
59 | protein K6-linked ubiquitination (GO:0085020) | 2.75209228 |
60 | telomere organization (GO:0032200) | 2.74815137 |
61 | protein prenylation (GO:0018342) | 2.74693904 |
62 | prenylation (GO:0097354) | 2.74693904 |
63 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.73485310 |
64 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.73358220 |
65 | DNA replication checkpoint (GO:0000076) | 2.73149331 |
66 | indole-containing compound catabolic process (GO:0042436) | 2.72681489 |
67 | indolalkylamine catabolic process (GO:0046218) | 2.72681489 |
68 | tryptophan catabolic process (GO:0006569) | 2.72681489 |
69 | kynurenine metabolic process (GO:0070189) | 2.72636931 |
70 | maturation of SSU-rRNA (GO:0030490) | 2.71608730 |
71 | viral mRNA export from host cell nucleus (GO:0046784) | 2.71588508 |
72 | telomere maintenance via telomere lengthening (GO:0010833) | 2.70144033 |
73 | adenosine metabolic process (GO:0046085) | 2.69507668 |
74 | somatic diversification of immunoglobulins (GO:0016445) | 2.68399756 |
75 | resolution of meiotic recombination intermediates (GO:0000712) | 2.67829646 |
76 | protein polyglutamylation (GO:0018095) | 2.67415956 |
77 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.66189559 |
78 | epithelial cilium movement (GO:0003351) | 2.66063699 |
79 | DNA strand elongation (GO:0022616) | 2.64817977 |
80 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.64009796 |
81 | translesion synthesis (GO:0019985) | 2.63007094 |
82 | ATP synthesis coupled proton transport (GO:0015986) | 2.61561491 |
83 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.61561491 |
84 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.61149161 |
85 | isotype switching (GO:0045190) | 2.61149161 |
86 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.61149161 |
87 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.60703691 |
88 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.60703691 |
89 | ubiquinone metabolic process (GO:0006743) | 2.59597957 |
90 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.59578733 |
91 | histone exchange (GO:0043486) | 2.59327475 |
92 | superoxide anion generation (GO:0042554) | 2.58893983 |
93 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.58779699 |
94 | DNA damage response, detection of DNA damage (GO:0042769) | 2.58182665 |
95 | pseudouridine synthesis (GO:0001522) | 2.57988850 |
96 | ubiquinone biosynthetic process (GO:0006744) | 2.57305037 |
97 | DNA synthesis involved in DNA repair (GO:0000731) | 2.57029882 |
98 | mismatch repair (GO:0006298) | 2.56688497 |
99 | rRNA methylation (GO:0031167) | 2.55917451 |
100 | cytidine deamination (GO:0009972) | 2.55892485 |
101 | cytidine metabolic process (GO:0046087) | 2.55892485 |
102 | cytidine catabolic process (GO:0006216) | 2.55892485 |
103 | somite development (GO:0061053) | 2.55821900 |
104 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.54219938 |
105 | DNA replication initiation (GO:0006270) | 2.52891227 |
106 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.52692682 |
107 | GPI anchor metabolic process (GO:0006505) | 2.50598401 |
108 | dendritic cell migration (GO:0036336) | 2.49183278 |
109 | termination of RNA polymerase I transcription (GO:0006363) | 2.48824359 |
110 | rRNA modification (GO:0000154) | 2.47581361 |
111 | DNA integration (GO:0015074) | 2.46977200 |
112 | histone mRNA metabolic process (GO:0008334) | 2.44899474 |
113 | tryptophan metabolic process (GO:0006568) | 2.44012986 |
114 | intraciliary transport (GO:0042073) | 2.42924758 |
115 | ribosomal small subunit biogenesis (GO:0042274) | 2.42142844 |
116 | RNA capping (GO:0036260) | 2.41668737 |
117 | 7-methylguanosine RNA capping (GO:0009452) | 2.41668737 |
118 | recombinational repair (GO:0000725) | 2.40245486 |
119 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.39776619 |
120 | DNA strand renaturation (GO:0000733) | 2.38511080 |
121 | fucose catabolic process (GO:0019317) | 2.37726170 |
122 | L-fucose metabolic process (GO:0042354) | 2.37726170 |
123 | L-fucose catabolic process (GO:0042355) | 2.37726170 |
124 | GPI anchor biosynthetic process (GO:0006506) | 2.37580887 |
125 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.37327600 |
126 | termination of RNA polymerase III transcription (GO:0006386) | 2.37327600 |
127 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.37067251 |
128 | DNA-dependent DNA replication (GO:0006261) | 2.36567637 |
129 | transcription from RNA polymerase I promoter (GO:0006360) | 2.36531109 |
130 | mannosylation (GO:0097502) | 2.34049798 |
131 | 7-methylguanosine mRNA capping (GO:0006370) | 2.33962093 |
132 | response to interferon-beta (GO:0035456) | 2.33756448 |
133 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.33334108 |
134 | RNA methylation (GO:0001510) | 2.32639100 |
135 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.32579203 |
136 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.32052889 |
137 | lymph node development (GO:0048535) | 2.31766086 |
138 | double-strand break repair via homologous recombination (GO:0000724) | 2.30853584 |
139 | DNA double-strand break processing (GO:0000729) | 2.30542974 |
140 | microtubule depolymerization (GO:0007019) | 2.30496412 |
141 | regulation of DNA endoreduplication (GO:0032875) | 2.30208777 |
142 | ribosomal large subunit biogenesis (GO:0042273) | 2.30197810 |
143 | maturation of 5.8S rRNA (GO:0000460) | 2.30023040 |
144 | interferon-gamma production (GO:0032609) | 2.29480491 |
145 | * tRNA processing (GO:0008033) | 2.28622967 |
146 | protein heterotetramerization (GO:0051290) | 2.28577666 |
147 | DNA recombination (GO:0006310) | 2.28572809 |
148 | * tRNA modification (GO:0006400) | 2.27577143 |
149 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.27469633 |
150 | RNA-dependent DNA replication (GO:0006278) | 2.27435627 |
151 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.27303495 |
152 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.27303495 |
153 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.26317220 |
154 | response to X-ray (GO:0010165) | 2.26169641 |
155 | histone H2A acetylation (GO:0043968) | 2.25177590 |
156 | regulation of RIG-I signaling pathway (GO:0039535) | 2.24804676 |
157 | DNA dealkylation (GO:0035510) | 2.23297456 |
158 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.23173251 |
159 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.22927284 |
160 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.20835905 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.05627928 |
2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.73098982 |
3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.27176987 |
4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.17473967 |
5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.14400176 |
6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.04387428 |
7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.03349261 |
8 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.91421139 |
9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.78999397 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.78571582 |
11 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.70641443 |
12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.54985548 |
13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.49931137 |
14 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.46162916 |
15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.43951895 |
16 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.43267812 |
17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.39388382 |
18 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.36605355 |
19 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.35254471 |
20 | * GBX2_23144817_ChIP-Seq_PC3_Human | 2.31146353 |
21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.28801398 |
22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.19655557 |
23 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.18988130 |
24 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.18721494 |
25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.14662014 |
26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.14446510 |
27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.12948929 |
28 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.11767688 |
29 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.08631527 |
30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.07715309 |
31 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.04816247 |
32 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.03493789 |
33 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.02700675 |
34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.02677980 |
35 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.00205299 |
36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.93974440 |
37 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.90466741 |
38 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.88337709 |
39 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.87160224 |
40 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.85241871 |
41 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.84881630 |
42 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.83329497 |
43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.82952091 |
44 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.71749138 |
45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.70936258 |
46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.69193169 |
47 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.67850944 |
48 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.67789739 |
49 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.67684194 |
50 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.66709488 |
51 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.63496564 |
52 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61754872 |
53 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.59731491 |
54 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58696102 |
55 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.57353078 |
56 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.56598192 |
57 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.56132861 |
58 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.54576112 |
59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.53060541 |
60 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.48464870 |
61 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.47158379 |
62 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.45911363 |
63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.45911363 |
64 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.44750950 |
65 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.44594588 |
66 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42849933 |
67 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.42782729 |
68 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.42266103 |
69 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41385552 |
70 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.37009319 |
71 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.36588886 |
72 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.35507733 |
73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.34815226 |
74 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34405110 |
75 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.34093586 |
76 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.32018693 |
77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31265085 |
78 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29812937 |
79 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.29655201 |
80 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.29431692 |
81 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.28324155 |
82 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.26596336 |
83 | * FUS_26573619_Chip-Seq_HEK293_Human | 1.26221245 |
84 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.25852514 |
85 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.25274677 |
86 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.24942038 |
87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.24824991 |
88 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.24824991 |
89 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24805011 |
90 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.24689561 |
91 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.24609774 |
92 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.24600246 |
93 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.24505166 |
94 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23268463 |
95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.21890890 |
96 | STAT3_23295773_ChIP-Seq_U87_Human | 1.21731562 |
97 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.19983616 |
98 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.19917230 |
99 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.19352156 |
100 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.19259671 |
101 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.16963896 |
102 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.16928916 |
103 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.16928916 |
104 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16707201 |
105 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.16707201 |
106 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.16429173 |
107 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.16193175 |
108 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.16014742 |
109 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.15792525 |
110 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15312747 |
111 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.15018870 |
112 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.14882414 |
113 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.13336789 |
114 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.11781525 |
115 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11191047 |
116 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.11151970 |
117 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.09126396 |
118 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.08416620 |
119 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08234296 |
120 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.08185917 |
121 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.07489718 |
122 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.06679200 |
123 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.05929948 |
124 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.05472408 |
125 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.05418223 |
126 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.05368287 |
127 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.04494378 |
128 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03629580 |
129 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.03204050 |
130 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03058185 |
131 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02803943 |
132 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.02301043 |
133 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.01869351 |
134 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.00810038 |
135 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.00670821 |
136 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00365629 |
137 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.98911664 |
138 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.98787843 |
139 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.98309380 |
140 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.98087134 |
141 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.98021573 |
142 | NCOR_22424771_ChIP-Seq_293T_Human | 0.97715297 |
143 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.97126798 |
144 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.96602733 |
145 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.95614546 |
146 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.95598465 |
147 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94749894 |
148 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.94551969 |
149 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94498340 |
150 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.94465217 |
151 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.92129213 |
152 | * TCF4_22108803_ChIP-Seq_LS180_Human | 0.91643079 |
153 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91163866 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0006292_abnormal_olfactory_placode | 3.10959087 |
2 | MP0008057_abnormal_DNA_replication | 3.05594058 |
3 | MP0003136_yellow_coat_color | 2.87060217 |
4 | MP0008058_abnormal_DNA_repair | 2.84705509 |
5 | MP0000566_synostosis | 2.84473626 |
6 | MP0005075_abnormal_melanosome_morpholog | 2.83435565 |
7 | MP0001835_abnormal_antigen_presentation | 2.72272389 |
8 | MP0001188_hyperpigmentation | 2.65940912 |
9 | MP0003763_abnormal_thymus_physiology | 2.64714788 |
10 | MP0000569_abnormal_digit_pigmentation | 2.62538135 |
11 | MP0004381_abnormal_hair_follicle | 2.62245369 |
12 | MP0001986_abnormal_taste_sensitivity | 2.59919356 |
13 | MP0010094_abnormal_chromosome_stability | 2.55672014 |
14 | MP0005174_abnormal_tail_pigmentation | 2.38470820 |
15 | MP0006072_abnormal_retinal_apoptosis | 2.38292171 |
16 | MP0005671_abnormal_response_to | 2.37845232 |
17 | MP0002396_abnormal_hematopoietic_system | 2.24392241 |
18 | MP0008007_abnormal_cellular_replicative | 2.17769468 |
19 | MP0000015_abnormal_ear_pigmentation | 2.17246053 |
20 | MP0003693_abnormal_embryo_hatching | 2.16975613 |
21 | MP0002009_preneoplasia | 2.14100314 |
22 | MP0009697_abnormal_copulation | 2.01975470 |
23 | MP0003646_muscle_fatigue | 2.01134576 |
24 | MP0003195_calcinosis | 1.99857794 |
25 | MP0002148_abnormal_hypersensitivity_rea | 1.93277341 |
26 | MP0005253_abnormal_eye_physiology | 1.91622609 |
27 | MP0002095_abnormal_skin_pigmentation | 1.88413839 |
28 | MP0002837_dystrophic_cardiac_calcinosis | 1.83389310 |
29 | MP0002277_abnormal_respiratory_mucosa | 1.82390738 |
30 | MP0009785_altered_susceptibility_to | 1.77708799 |
31 | MP0005551_abnormal_eye_electrophysiolog | 1.76616226 |
32 | MP0000490_abnormal_crypts_of | 1.74765900 |
33 | MP0000372_irregular_coat_pigmentation | 1.66431293 |
34 | MP0003786_premature_aging | 1.66372726 |
35 | MP0002234_abnormal_pharynx_morphology | 1.66211456 |
36 | MP0002132_abnormal_respiratory_system | 1.66094729 |
37 | MP0004145_abnormal_muscle_electrophysio | 1.65088998 |
38 | MP0000685_abnormal_immune_system | 1.64782936 |
39 | MP0008872_abnormal_physiological_respon | 1.63707020 |
40 | MP0005171_absent_coat_pigmentation | 1.62557148 |
41 | MP0003077_abnormal_cell_cycle | 1.62350175 |
42 | MP0003111_abnormal_nucleus_morphology | 1.60618774 |
43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.60590766 |
44 | MP0008995_early_reproductive_senescence | 1.60200904 |
45 | MP0008877_abnormal_DNA_methylation | 1.57239980 |
46 | MP0001800_abnormal_humoral_immune | 1.56808016 |
47 | MP0001529_abnormal_vocalization | 1.55670044 |
48 | MP0003724_increased_susceptibility_to | 1.51316781 |
49 | MP0009379_abnormal_foot_pigmentation | 1.51118202 |
50 | MP0003880_abnormal_central_pattern | 1.50770828 |
51 | MP0000631_abnormal_neuroendocrine_gland | 1.50059353 |
52 | MP0002751_abnormal_autonomic_nervous | 1.48712924 |
53 | MP0003121_genomic_imprinting | 1.48113292 |
54 | MP0004142_abnormal_muscle_tone | 1.47726994 |
55 | MP0006276_abnormal_autonomic_nervous | 1.46219089 |
56 | MP0002452_abnormal_antigen_presenting | 1.45700927 |
57 | MP0002420_abnormal_adaptive_immunity | 1.44639471 |
58 | MP0002723_abnormal_immune_serum | 1.43672867 |
59 | MP0005000_abnormal_immune_tolerance | 1.43326922 |
60 | MP0001819_abnormal_immune_cell | 1.42280823 |
61 | MP0002398_abnormal_bone_marrow | 1.38010049 |
62 | MP0005025_abnormal_response_to | 1.35190313 |
63 | MP0002166_altered_tumor_susceptibility | 1.34063968 |
64 | MP0002102_abnormal_ear_morphology | 1.33196627 |
65 | MP0001873_stomach_inflammation | 1.32310545 |
66 | MP0002419_abnormal_innate_immunity | 1.30652264 |
67 | MP0005387_immune_system_phenotype | 1.29577145 |
68 | MP0001790_abnormal_immune_system | 1.29577145 |
69 | MP0001853_heart_inflammation | 1.27773717 |
70 | MP0001293_anophthalmia | 1.26892456 |
71 | MP0005409_darkened_coat_color | 1.26817713 |
72 | MP0004133_heterotaxia | 1.26167835 |
73 | MP0002736_abnormal_nociception_after | 1.26037989 |
74 | MP0005084_abnormal_gallbladder_morpholo | 1.24558854 |
75 | MP0009333_abnormal_splenocyte_physiolog | 1.23979914 |
76 | MP0002006_tumorigenesis | 1.23716436 |
77 | MP0004147_increased_porphyrin_level | 1.21596491 |
78 | MP0000689_abnormal_spleen_morphology | 1.21061580 |
79 | MP0009046_muscle_twitch | 1.20779807 |
80 | MP0002938_white_spotting | 1.18642490 |
81 | MP0000716_abnormal_immune_system | 1.18097301 |
82 | MP0000427_abnormal_hair_cycle | 1.16432061 |
83 | MP0003941_abnormal_skin_development | 1.15628521 |
84 | MP0002163_abnormal_gland_morphology | 1.13044445 |
85 | MP0001968_abnormal_touch/_nociception | 1.12936381 |
86 | MP0000703_abnormal_thymus_morphology | 1.12580925 |
87 | MP0003011_delayed_dark_adaptation | 1.12470693 |
88 | MP0002405_respiratory_system_inflammati | 1.12286303 |
89 | MP0008789_abnormal_olfactory_epithelium | 1.11675033 |
90 | MP0002160_abnormal_reproductive_system | 1.10879747 |
91 | MP0004808_abnormal_hematopoietic_stem | 1.10422938 |
92 | MP0001984_abnormal_olfaction | 1.09780652 |
93 | MP0004782_abnormal_surfactant_physiolog | 1.09677605 |
94 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09575848 |
95 | MP0001545_abnormal_hematopoietic_system | 1.09133520 |
96 | MP0005397_hematopoietic_system_phenotyp | 1.09133520 |
97 | MP0002653_abnormal_ependyma_morphology | 1.08441199 |
98 | MP0003937_abnormal_limbs/digits/tail_de | 1.08028207 |
99 | MP0002722_abnormal_immune_system | 1.07799475 |
100 | MP0003890_abnormal_embryonic-extraembry | 1.05287335 |
101 | MP0002429_abnormal_blood_cell | 1.03955221 |
102 | MP0000383_abnormal_hair_follicle | 1.03771703 |
103 | MP0008260_abnormal_autophagy | 1.02704793 |
104 | MP0005389_reproductive_system_phenotype | 1.02298015 |
105 | MP0000653_abnormal_sex_gland | 1.01359900 |
106 | MP0002638_abnormal_pupillary_reflex | 0.99490680 |
107 | MP0003718_maternal_effect | 0.99191072 |
108 | MP0005464_abnormal_platelet_physiology | 0.99109552 |
109 | MP0005410_abnormal_fertilization | 0.98838370 |
110 | MP0003943_abnormal_hepatobiliary_system | 0.98591080 |
111 | MP0002075_abnormal_coat/hair_pigmentati | 0.98413759 |
112 | MP0001186_pigmentation_phenotype | 0.97481836 |
113 | MP0005646_abnormal_pituitary_gland | 0.96814862 |
114 | MP0005379_endocrine/exocrine_gland_phen | 0.96057630 |
115 | MP0000647_abnormal_sebaceous_gland | 0.95411560 |
116 | MP0010155_abnormal_intestine_physiology | 0.95291540 |
117 | MP0002210_abnormal_sex_determination | 0.95039849 |
118 | MP0006035_abnormal_mitochondrial_morpho | 0.94982580 |
119 | MP0001119_abnormal_female_reproductive | 0.93663482 |
120 | MP0001485_abnormal_pinna_reflex | 0.93638938 |
121 | MP0006036_abnormal_mitochondrial_physio | 0.92459360 |
122 | MP0003122_maternal_imprinting | 0.92347545 |
123 | MP0003436_decreased_susceptibility_to | 0.91817015 |
124 | MP0003186_abnormal_redox_activity | 0.90734573 |
125 | MP0004043_abnormal_pH_regulation | 0.90026504 |
126 | MP0008775_abnormal_heart_ventricle | 0.89423266 |
127 | MP0002735_abnormal_chemical_nociception | 0.89318517 |
128 | MP0001145_abnormal_male_reproductive | 0.89280894 |
129 | MP0005391_vision/eye_phenotype | 0.88690891 |
130 | MP0001929_abnormal_gametogenesis | 0.88526776 |
131 | MP0002138_abnormal_hepatobiliary_system | 0.88368567 |
132 | MP0000613_abnormal_salivary_gland | 0.88006616 |
133 | MP0002876_abnormal_thyroid_physiology | 0.86308716 |
134 | MP0005195_abnormal_posterior_eye | 0.85036331 |
135 | MP0010386_abnormal_urinary_bladder | 0.84728310 |
136 | MP0009745_abnormal_behavioral_response | 0.83902333 |
137 | MP0003698_abnormal_male_reproductive | 0.83689116 |
138 | MP0005408_hypopigmentation | 0.82787336 |
139 | MP0002557_abnormal_social/conspecific_i | 0.81270063 |
140 | MP0004215_abnormal_myocardial_fiber | 0.80391782 |
141 | MP0008932_abnormal_embryonic_tissue | 0.79297848 |
142 | MP0000049_abnormal_middle_ear | 0.79209467 |
143 | MP0001919_abnormal_reproductive_system | 0.79043388 |
144 | MP0001346_abnormal_lacrimal_gland | 0.78599016 |
145 | MP0002254_reproductive_system_inflammat | 0.78339705 |
146 | MP0004957_abnormal_blastocyst_morpholog | 0.77968535 |
147 | MP0005645_abnormal_hypothalamus_physiol | 0.77589148 |
148 | MP0001286_abnormal_eye_development | 0.76606467 |
149 | MP0002272_abnormal_nervous_system | 0.76028326 |
150 | MP0004134_abnormal_chest_morphology | 0.75589213 |
151 | MP0000465_gastrointestinal_hemorrhage | 0.74995864 |
152 | MP0005187_abnormal_penis_morphology | 0.74854326 |
153 | MP0005394_taste/olfaction_phenotype | 0.74577715 |
154 | MP0005499_abnormal_olfactory_system | 0.74577715 |
155 | MP0002928_abnormal_bile_duct | 0.72592322 |
156 | MP0005266_abnormal_metabolism | 0.71983808 |
157 | MP0003787_abnormal_imprinting | 0.70925223 |
158 | MP0001905_abnormal_dopamine_level | 0.70672091 |
159 | MP0003137_abnormal_impulse_conducting | 0.70476060 |
160 | MP0001764_abnormal_homeostasis | 0.69874301 |
161 | MP0001845_abnormal_inflammatory_respons | 0.69339783 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.77487352 |
2 | Chromsome breakage (HP:0040012) | 4.67462261 |
3 | Molar tooth sign on MRI (HP:0002419) | 3.43806470 |
4 | Abnormality of midbrain morphology (HP:0002418) | 3.43806470 |
5 | Type I transferrin isoform profile (HP:0003642) | 3.31967694 |
6 | Abnormality of the renal collecting system (HP:0004742) | 3.29649460 |
7 | Nephronophthisis (HP:0000090) | 3.07632970 |
8 | Reticulocytopenia (HP:0001896) | 3.06085039 |
9 | Medial flaring of the eyebrow (HP:0010747) | 3.04597512 |
10 | Duplicated collecting system (HP:0000081) | 3.03617839 |
11 | Prostate neoplasm (HP:0100787) | 3.02387857 |
12 | Abnormality of the preputium (HP:0100587) | 2.91203750 |
13 | Type 2 muscle fiber atrophy (HP:0003554) | 2.87640304 |
14 | True hermaphroditism (HP:0010459) | 2.85702359 |
15 | Colon cancer (HP:0003003) | 2.79992364 |
16 | Acute necrotizing encephalopathy (HP:0006965) | 2.79775806 |
17 | Abnormality of chromosome stability (HP:0003220) | 2.75451590 |
18 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.74830138 |
19 | Abnormality of the renal medulla (HP:0100957) | 2.71736844 |
20 | Acute encephalopathy (HP:0006846) | 2.69158880 |
21 | Meckel diverticulum (HP:0002245) | 2.68122017 |
22 | Clubbing of toes (HP:0100760) | 2.67407096 |
23 | Abnormality of the renal cortex (HP:0011035) | 2.64084506 |
24 | Reduced antithrombin III activity (HP:0001976) | 2.63922146 |
25 | Methylmalonic acidemia (HP:0002912) | 2.62202207 |
26 | Abnormality of the ileum (HP:0001549) | 2.59062365 |
27 | Abnormality of the prostate (HP:0008775) | 2.58557571 |
28 | Congenital stationary night blindness (HP:0007642) | 2.58415388 |
29 | Chronic hepatic failure (HP:0100626) | 2.58356008 |
30 | Patchy hypopigmentation of hair (HP:0011365) | 2.57278061 |
31 | Abnormality of DNA repair (HP:0003254) | 2.53538569 |
32 | Mitochondrial inheritance (HP:0001427) | 2.51328519 |
33 | Increased CSF lactate (HP:0002490) | 2.50936416 |
34 | Aplastic anemia (HP:0001915) | 2.49800598 |
35 | Progressive macrocephaly (HP:0004481) | 2.49243343 |
36 | White forelock (HP:0002211) | 2.48410704 |
37 | Dry hair (HP:0011359) | 2.47527359 |
38 | 11 pairs of ribs (HP:0000878) | 2.46685706 |
39 | Optic neuritis (HP:0100653) | 2.45605761 |
40 | Retrobulbar optic neuritis (HP:0100654) | 2.45605761 |
41 | IgM deficiency (HP:0002850) | 2.45424269 |
42 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.43998587 |
43 | Abnormality of the columella (HP:0009929) | 2.42355175 |
44 | Methylmalonic aciduria (HP:0012120) | 2.41950918 |
45 | Pancreatic fibrosis (HP:0100732) | 2.41653715 |
46 | Abnormality of the labia minora (HP:0012880) | 2.41186155 |
47 | Microvesicular hepatic steatosis (HP:0001414) | 2.39501544 |
48 | Abnormal number of erythroid precursors (HP:0012131) | 2.39153423 |
49 | Tubulointerstitial nephritis (HP:0001970) | 2.38484154 |
50 | 3-Methylglutaconic aciduria (HP:0003535) | 2.37489652 |
51 | Intestinal atresia (HP:0011100) | 2.37335126 |
52 | Supernumerary spleens (HP:0009799) | 2.35706211 |
53 | Muscle fiber atrophy (HP:0100295) | 2.34763675 |
54 | Pancreatic cysts (HP:0001737) | 2.33896725 |
55 | Hyperventilation (HP:0002883) | 2.31589879 |
56 | Abnormal protein glycosylation (HP:0012346) | 2.29368889 |
57 | Abnormal glycosylation (HP:0012345) | 2.29368889 |
58 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.29368889 |
59 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.29368889 |
60 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.27646355 |
61 | Birth length less than 3rd percentile (HP:0003561) | 2.27559491 |
62 | Myositis (HP:0100614) | 2.27072272 |
63 | Abolished electroretinogram (ERG) (HP:0000550) | 2.25775876 |
64 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.25522209 |
65 | Absent/shortened dynein arms (HP:0200106) | 2.25522209 |
66 | Myelodysplasia (HP:0002863) | 2.22679340 |
67 | Ectopic kidney (HP:0000086) | 2.20624150 |
68 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.19836108 |
69 | Asplenia (HP:0001746) | 2.18946519 |
70 | Cystic liver disease (HP:0006706) | 2.17810838 |
71 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.16627736 |
72 | Hepatocellular necrosis (HP:0001404) | 2.16310260 |
73 | Small intestinal stenosis (HP:0012848) | 2.13978871 |
74 | Duodenal stenosis (HP:0100867) | 2.13978871 |
75 | Type II lissencephaly (HP:0007260) | 2.12794835 |
76 | Abnormal hair whorl (HP:0010721) | 2.10765570 |
77 | Hypergonadotropic hypogonadism (HP:0000815) | 2.10705003 |
78 | Hypothermia (HP:0002045) | 2.10373213 |
79 | Congenital primary aphakia (HP:0007707) | 2.10371078 |
80 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.09763276 |
81 | Abnormality of secondary sexual hair (HP:0009888) | 2.06185698 |
82 | Abnormality of the axillary hair (HP:0100134) | 2.06185698 |
83 | Ependymoma (HP:0002888) | 2.05938725 |
84 | Bone marrow hypocellularity (HP:0005528) | 2.05812702 |
85 | Lipid accumulation in hepatocytes (HP:0006561) | 2.05714725 |
86 | Renal cortical cysts (HP:0000803) | 2.05352465 |
87 | Gait imbalance (HP:0002141) | 2.04543661 |
88 | Recurrent abscess formation (HP:0002722) | 2.03403413 |
89 | Hepatic necrosis (HP:0002605) | 2.02395955 |
90 | Gaze-evoked nystagmus (HP:0000640) | 2.02300176 |
91 | Short tibia (HP:0005736) | 2.01978942 |
92 | Abnormality of alanine metabolism (HP:0010916) | 2.01654591 |
93 | Hyperalaninemia (HP:0003348) | 2.01654591 |
94 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.01654591 |
95 | Thyroiditis (HP:0100646) | 2.01334497 |
96 | Sclerocornea (HP:0000647) | 2.00677478 |
97 | Volvulus (HP:0002580) | 1.99725932 |
98 | Duplication of thumb phalanx (HP:0009942) | 1.98139185 |
99 | Glioma (HP:0009733) | 1.97396696 |
100 | Male pseudohermaphroditism (HP:0000037) | 1.97268933 |
101 | Aplasia cutis congenita (HP:0001057) | 1.95117485 |
102 | Abnormal lung lobation (HP:0002101) | 1.94889801 |
103 | Pancytopenia (HP:0001876) | 1.94667485 |
104 | Abnormal biliary tract physiology (HP:0012439) | 1.94341227 |
105 | Bile duct proliferation (HP:0001408) | 1.94341227 |
106 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.92931006 |
107 | Increased serum lactate (HP:0002151) | 1.92650306 |
108 | Anencephaly (HP:0002323) | 1.92033723 |
109 | Genital tract atresia (HP:0001827) | 1.91760729 |
110 | Attenuation of retinal blood vessels (HP:0007843) | 1.91759553 |
111 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91480600 |
112 | Hyperglycinemia (HP:0002154) | 1.91291355 |
113 | Lip pit (HP:0100267) | 1.91067019 |
114 | Pendular nystagmus (HP:0012043) | 1.89800483 |
115 | Thrombocytosis (HP:0001894) | 1.89273508 |
116 | Nephrogenic diabetes insipidus (HP:0009806) | 1.88692482 |
117 | Cerebral edema (HP:0002181) | 1.88561501 |
118 | Chronic diarrhea (HP:0002028) | 1.87884430 |
119 | IgG deficiency (HP:0004315) | 1.87655020 |
120 | Abnormality of the pons (HP:0007361) | 1.85352138 |
121 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.84786401 |
122 | Premature graying of hair (HP:0002216) | 1.84574940 |
123 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.84083016 |
124 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.84083016 |
125 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.84077468 |
126 | Vaginal atresia (HP:0000148) | 1.83127097 |
127 | Orchitis (HP:0100796) | 1.82531235 |
128 | Congenital hepatic fibrosis (HP:0002612) | 1.82046765 |
129 | Hypoplasia of the pons (HP:0012110) | 1.81205271 |
130 | Sloping forehead (HP:0000340) | 1.81083422 |
131 | Congenital, generalized hypertrichosis (HP:0004540) | 1.80689297 |
132 | Amaurosis fugax (HP:0100576) | 1.80503591 |
133 | Prolonged bleeding time (HP:0003010) | 1.80481803 |
134 | Nonprogressive disorder (HP:0003680) | 1.78775364 |
135 | Triphalangeal thumb (HP:0001199) | 1.78203415 |
136 | Abnormality of male internal genitalia (HP:0000022) | 1.78165406 |
137 | Pallor (HP:0000980) | 1.77418453 |
138 | Preaxial hand polydactyly (HP:0001177) | 1.77394178 |
139 | Absent speech (HP:0001344) | 1.77228329 |
140 | Optic nerve hypoplasia (HP:0000609) | 1.76657565 |
141 | Patellar aplasia (HP:0006443) | 1.76302154 |
142 | Astrocytoma (HP:0009592) | 1.75629109 |
143 | Abnormality of the astrocytes (HP:0100707) | 1.75629109 |
144 | Lymphoma (HP:0002665) | 1.75587743 |
145 | Abnormality of the duodenum (HP:0002246) | 1.75153132 |
146 | Recurrent bacterial skin infections (HP:0005406) | 1.74782181 |
147 | Mediastinal lymphadenopathy (HP:0100721) | 1.74676589 |
148 | Septo-optic dysplasia (HP:0100842) | 1.74431517 |
149 | Lactic acidosis (HP:0003128) | 1.73511761 |
150 | Postaxial foot polydactyly (HP:0001830) | 1.73481812 |
151 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.73093887 |
152 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.73062246 |
153 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.72409585 |
154 | Embryonal renal neoplasm (HP:0011794) | 1.72117082 |
155 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.71595145 |
156 | Abnormal spermatogenesis (HP:0008669) | 1.71509133 |
157 | Dandy-Walker malformation (HP:0001305) | 1.71181621 |
158 | Keratoconjunctivitis (HP:0001096) | 1.70430476 |
159 | Anhidrosis (HP:0000970) | 1.70388305 |
160 | Petechiae (HP:0000967) | 1.69834139 |
161 | Postaxial hand polydactyly (HP:0001162) | 1.69580834 |
162 | Cerebellar dysplasia (HP:0007033) | 1.69522780 |
163 | Lissencephaly (HP:0001339) | 1.68598565 |
164 | Optic disc pallor (HP:0000543) | 1.68285210 |
165 | Recurrent pneumonia (HP:0006532) | 1.68096673 |
166 | Furrowed tongue (HP:0000221) | 1.67646466 |
167 | Fair hair (HP:0002286) | 1.66874687 |
168 | Hypoplasia of the thymus (HP:0000778) | 1.66305086 |
169 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.65585343 |
170 | Tubular atrophy (HP:0000092) | 1.65582661 |
171 | Thyroid-stimulating hormone excess (HP:0002925) | 1.64740061 |
172 | Weak cry (HP:0001612) | 1.63416303 |
173 | Increased hepatocellular lipid droplets (HP:0006565) | 1.63298174 |
174 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.62666892 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 3.93346225 |
2 | STK16 | 3.22692290 |
3 | TXK | 3.14389977 |
4 | MAP4K2 | 3.06181651 |
5 | IRAK3 | 2.85885409 |
6 | MUSK | 2.85053189 |
7 | ZAK | 2.61085848 |
8 | SRPK1 | 2.61068387 |
9 | VRK2 | 2.50603018 |
10 | MAP3K14 | 2.45090437 |
11 | IRAK4 | 2.35933982 |
12 | TRIM28 | 2.34529763 |
13 | WNK3 | 2.32370531 |
14 | MKNK1 | 2.26535801 |
15 | CASK | 2.23113777 |
16 | MKNK2 | 2.17671758 |
17 | TNIK | 2.12423266 |
18 | PLK4 | 2.11257104 |
19 | TEC | 1.91133504 |
20 | VRK1 | 1.78031993 |
21 | EIF2AK2 | 1.69317201 |
22 | BMPR1B | 1.67956301 |
23 | BCKDK | 1.63173580 |
24 | MAP3K4 | 1.59267479 |
25 | MST4 | 1.56221886 |
26 | NUAK1 | 1.49883248 |
27 | BUB1 | 1.47742322 |
28 | NEK6 | 1.45711606 |
29 | EIF2AK1 | 1.43803845 |
30 | MAPK13 | 1.42616296 |
31 | YES1 | 1.41749774 |
32 | CDK8 | 1.41561724 |
33 | BCR | 1.39844453 |
34 | KIT | 1.38513401 |
35 | IKBKB | 1.30761549 |
36 | JAK3 | 1.30672967 |
37 | NLK | 1.29491795 |
38 | MAP4K1 | 1.27935026 |
39 | ADRBK2 | 1.23123289 |
40 | EIF2AK3 | 1.19491679 |
41 | INSRR | 1.18318156 |
42 | IKBKE | 1.15733780 |
43 | CDC7 | 1.12377736 |
44 | PLK2 | 1.11441968 |
45 | CLK1 | 1.10910810 |
46 | CSNK1G1 | 1.10560484 |
47 | WEE1 | 1.10332549 |
48 | CSNK1G2 | 1.06868152 |
49 | NME2 | 1.06799154 |
50 | BTK | 1.06062374 |
51 | BMPR2 | 1.05536397 |
52 | CSNK1G3 | 1.05282181 |
53 | ERBB3 | 1.04696448 |
54 | GRK1 | 1.01347818 |
55 | ATR | 1.01337393 |
56 | DYRK2 | 0.98467700 |
57 | OXSR1 | 0.97209104 |
58 | TLK1 | 0.97073385 |
59 | NEK1 | 0.96538673 |
60 | CDK3 | 0.95676761 |
61 | TIE1 | 0.95240092 |
62 | PIM1 | 0.95135896 |
63 | ACVR1B | 0.95125034 |
64 | TRPM7 | 0.94735619 |
65 | PIK3CG | 0.94280367 |
66 | IRAK1 | 0.93738493 |
67 | TAF1 | 0.91677225 |
68 | BRSK2 | 0.91567428 |
69 | CSNK1A1L | 0.90459330 |
70 | DYRK3 | 0.87542879 |
71 | SIK3 | 0.86506882 |
72 | CHUK | 0.86086394 |
73 | MAP2K7 | 0.85510472 |
74 | BRD4 | 0.85302666 |
75 | NME1 | 0.84405064 |
76 | PIM2 | 0.81203846 |
77 | GRK7 | 0.79353856 |
78 | RPS6KA5 | 0.78249275 |
79 | STK24 | 0.76702613 |
80 | NEK9 | 0.75905373 |
81 | STK39 | 0.75252682 |
82 | ZAP70 | 0.74494271 |
83 | PRKCE | 0.71439335 |
84 | AURKB | 0.70756430 |
85 | ITK | 0.70089024 |
86 | LYN | 0.68762364 |
87 | PLK1 | 0.68612401 |
88 | PAK3 | 0.68571705 |
89 | CDK7 | 0.68479659 |
90 | PNCK | 0.68465947 |
91 | IRAK2 | 0.67961641 |
92 | EPHA3 | 0.67499975 |
93 | WNK4 | 0.64129861 |
94 | PRPF4B | 0.63823200 |
95 | LCK | 0.62203610 |
96 | MAPKAPK5 | 0.61863484 |
97 | TAOK3 | 0.60054920 |
98 | PINK1 | 0.58722517 |
99 | AKT3 | 0.57563508 |
100 | MAPKAPK3 | 0.56214194 |
101 | MAP2K6 | 0.55930827 |
102 | PRKCG | 0.55297798 |
103 | SGK2 | 0.55285766 |
104 | TTK | 0.55283658 |
105 | STK4 | 0.55012704 |
106 | CHEK2 | 0.54566650 |
107 | OBSCN | 0.54213778 |
108 | SYK | 0.54167605 |
109 | TGFBR1 | 0.53943651 |
110 | CHEK1 | 0.53876302 |
111 | PBK | 0.51773719 |
112 | CCNB1 | 0.51707572 |
113 | PASK | 0.51321052 |
114 | CSF1R | 0.51169213 |
115 | ADRBK1 | 0.50868266 |
116 | ATM | 0.50379670 |
117 | PLK3 | 0.49163204 |
118 | STK3 | 0.46787881 |
119 | EPHA4 | 0.46075037 |
120 | FGFR2 | 0.45289261 |
121 | CSNK2A1 | 0.45158821 |
122 | TYK2 | 0.43042006 |
123 | NEK2 | 0.42717091 |
124 | PKN1 | 0.42646057 |
125 | PHKG2 | 0.42528188 |
126 | PHKG1 | 0.42528188 |
127 | MAPK15 | 0.41934091 |
128 | BLK | 0.41798893 |
129 | FER | 0.41653586 |
130 | FLT3 | 0.41626327 |
131 | MYLK | 0.40835456 |
132 | MELK | 0.39943892 |
133 | RPS6KA6 | 0.39152336 |
134 | ERBB2 | 0.38964327 |
135 | PRKCQ | 0.37811083 |
136 | CAMKK2 | 0.37364007 |
137 | TSSK6 | 0.37248529 |
138 | CSNK1A1 | 0.36697746 |
139 | PIK3CA | 0.36468832 |
140 | MAP3K12 | 0.35482381 |
141 | MAP2K3 | 0.35004256 |
142 | RPS6KA4 | 0.34696556 |
143 | STK38L | 0.33716279 |
144 | PRKACA | 0.32591214 |
145 | CSNK2A2 | 0.31440121 |
146 | PRKAA1 | 0.28822266 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.42610973 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.40141320 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 3.38911798 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 3.05985101 |
5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.88992998 |
6 | Ribosome_Homo sapiens_hsa03010 | 2.61926265 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.59677853 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.53714658 |
9 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.34818873 |
10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.33464600 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.20084317 |
12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.17983068 |
13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.10129445 |
14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.05671987 |
15 | Protein export_Homo sapiens_hsa03060 | 1.99961447 |
16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.97411817 |
17 | Proteasome_Homo sapiens_hsa03050 | 1.91484115 |
18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.85169019 |
19 | Spliceosome_Homo sapiens_hsa03040 | 1.77032252 |
20 | Allograft rejection_Homo sapiens_hsa05330 | 1.74462146 |
21 | RNA degradation_Homo sapiens_hsa03018 | 1.73508083 |
22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.71202802 |
23 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.69426252 |
24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.65222712 |
25 | Cell cycle_Homo sapiens_hsa04110 | 1.65042291 |
26 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.64349549 |
27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.59557911 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.59415254 |
29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.58716585 |
30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.56940205 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.55971525 |
32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.53149083 |
33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51231309 |
34 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.48920332 |
35 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.47617059 |
36 | Purine metabolism_Homo sapiens_hsa00230 | 1.42660588 |
37 | Measles_Homo sapiens_hsa05162 | 1.40350673 |
38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.38690449 |
39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.31753896 |
40 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.31641819 |
41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.27985279 |
42 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.27124718 |
43 | Peroxisome_Homo sapiens_hsa04146 | 1.26421592 |
44 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.22361524 |
45 | Alzheimers disease_Homo sapiens_hsa05010 | 1.21755305 |
46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.21536749 |
47 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.21019751 |
48 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.20557080 |
49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.16028909 |
50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.10867811 |
51 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.07955046 |
52 | RNA transport_Homo sapiens_hsa03013 | 1.07665858 |
53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.05187028 |
54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.04993355 |
55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.99103990 |
56 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.99021163 |
57 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98723292 |
58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.91656488 |
59 | Asthma_Homo sapiens_hsa05310 | 0.91257662 |
60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.91049518 |
61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.89946358 |
62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89142334 |
63 | Other glycan degradation_Homo sapiens_hsa00511 | 0.88515639 |
64 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.88482006 |
65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86957480 |
66 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.86757639 |
67 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85937372 |
68 | Taste transduction_Homo sapiens_hsa04742 | 0.83322027 |
69 | Leishmaniasis_Homo sapiens_hsa05140 | 0.81773054 |
70 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.80153087 |
71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.79644616 |
72 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.79594790 |
73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.75010419 |
74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.73644239 |
75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72813960 |
76 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.72601559 |
77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.71961870 |
78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71233474 |
79 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.70148797 |
80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69769697 |
81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.69661475 |
82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69572282 |
83 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.69502449 |
84 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.69347930 |
85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.69109685 |
86 | Influenza A_Homo sapiens_hsa05164 | 0.65905832 |
87 | Malaria_Homo sapiens_hsa05144 | 0.64848207 |
88 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.60231271 |
89 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.59224299 |
90 | Alcoholism_Homo sapiens_hsa05034 | 0.58602103 |
91 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.58548327 |
92 | Huntingtons disease_Homo sapiens_hsa05016 | 0.58246913 |
93 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56575731 |
94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55228844 |
95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55042374 |
96 | Legionellosis_Homo sapiens_hsa05134 | 0.54007034 |
97 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.51242347 |
98 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.50911564 |
99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.50793582 |
100 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49420631 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.48792627 |
102 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47312557 |
103 | Parkinsons disease_Homo sapiens_hsa05012 | 0.47192505 |
104 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46826264 |
105 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.46495475 |
106 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45554467 |
107 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.44984552 |
108 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.43790314 |
109 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.43693375 |
110 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.43285742 |
111 | ABC transporters_Homo sapiens_hsa02010 | 0.42997062 |
112 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41618479 |
113 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.40776304 |
114 | HTLV-I infection_Homo sapiens_hsa05166 | 0.40511269 |
115 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40136216 |
116 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39204016 |
117 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.38885576 |
118 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.37946850 |
119 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.37759882 |
120 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.35906942 |
121 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35680840 |
122 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34584928 |
123 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.34385688 |
124 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.33987396 |
125 | Hepatitis B_Homo sapiens_hsa05161 | 0.33925225 |
126 | Phototransduction_Homo sapiens_hsa04744 | 0.33597564 |
127 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.33501668 |
128 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33098709 |
129 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.33047685 |
130 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32660805 |
131 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32212281 |
132 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.31820948 |
133 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.31420794 |
134 | Morphine addiction_Homo sapiens_hsa05032 | 0.30128651 |
135 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.28641076 |
136 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27647985 |
137 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.26789931 |
138 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.23424517 |
139 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.22360862 |
140 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.22131147 |
141 | Pertussis_Homo sapiens_hsa05133 | 0.21571229 |
142 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.20835272 |
143 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.19797308 |