Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.08723994 |
2 | regulation of vitamin metabolic process (GO:0030656) | 4.14568541 |
3 | wound healing, spreading of epidermal cells (GO:0035313) | 4.03624959 |
4 | cell adhesion mediated by integrin (GO:0033627) | 3.71009741 |
5 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 3.67089454 |
6 | activation of MAPKKK activity (GO:0000185) | 3.65254524 |
7 | adhesion of symbiont to host cell (GO:0044650) | 3.64319371 |
8 | virion attachment to host cell (GO:0019062) | 3.64319371 |
9 | protein localization to endosome (GO:0036010) | 3.64094051 |
10 | positive regulation by symbiont of host defense response (GO:0052509) | 3.62247738 |
11 | modulation by symbiont of host defense response (GO:0052031) | 3.62247738 |
12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.62247738 |
13 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.62247738 |
14 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.62247738 |
15 | modulation by symbiont of host immune response (GO:0052553) | 3.62247738 |
16 | cellular response to interferon-alpha (GO:0035457) | 3.58820425 |
17 | positive regulation of interferon-alpha production (GO:0032727) | 3.52475021 |
18 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.50786976 |
19 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.47959894 |
20 | glycosphingolipid catabolic process (GO:0046479) | 3.47650612 |
21 | neutrophil activation involved in immune response (GO:0002283) | 3.41614923 |
22 | regulation of chronic inflammatory response (GO:0002676) | 3.39111392 |
23 | regulation of interferon-alpha production (GO:0032647) | 3.33982009 |
24 | regulation of mononuclear cell migration (GO:0071675) | 3.33255437 |
25 | response to muramyl dipeptide (GO:0032495) | 3.32889822 |
26 | negative regulation of interleukin-12 production (GO:0032695) | 3.27737885 |
27 | response to peptidoglycan (GO:0032494) | 3.27266927 |
28 | natural killer cell mediated immunity (GO:0002228) | 3.25386523 |
29 | natural killer cell mediated cytotoxicity (GO:0042267) | 3.25386523 |
30 | adhesion of symbiont to host (GO:0044406) | 3.23081682 |
31 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.23020631 |
32 | oligosaccharide catabolic process (GO:0009313) | 3.20496202 |
33 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.18818207 |
34 | glycolipid catabolic process (GO:0019377) | 3.16151642 |
35 | regulation of fever generation (GO:0031620) | 3.15870519 |
36 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.15804851 |
37 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 3.15345826 |
38 | wound healing, spreading of cells (GO:0044319) | 3.14582671 |
39 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.14256940 |
40 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.12175199 |
41 | decidualization (GO:0046697) | 3.11614884 |
42 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.99394934 |
43 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.98831821 |
44 | low-density lipoprotein particle clearance (GO:0034383) | 2.97008684 |
45 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.95885694 |
46 | endodermal cell differentiation (GO:0035987) | 2.92530555 |
47 | regulation of integrin activation (GO:0033623) | 2.90760399 |
48 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.88889118 |
49 | response to interferon-alpha (GO:0035455) | 2.88591759 |
50 | monocyte chemotaxis (GO:0002548) | 2.83749489 |
51 | chondrocyte proliferation (GO:0035988) | 2.82555324 |
52 | immunoglobulin mediated immune response (GO:0016064) | 2.81337801 |
53 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.79864557 |
54 | response to type I interferon (GO:0034340) | 2.79539001 |
55 | ceramide catabolic process (GO:0046514) | 2.79010198 |
56 | barbed-end actin filament capping (GO:0051016) | 2.78584375 |
57 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.77203011 |
58 | cellular response to type I interferon (GO:0071357) | 2.77182930 |
59 | type I interferon signaling pathway (GO:0060337) | 2.77182930 |
60 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.76744749 |
61 | membrane lipid catabolic process (GO:0046466) | 2.76511586 |
62 | regulation of protein heterodimerization activity (GO:0043497) | 2.76479094 |
63 | apoptotic cell clearance (GO:0043277) | 2.74643462 |
64 | positive regulation of p38MAPK cascade (GO:1900745) | 2.74625787 |
65 | regulation of monocyte chemotaxis (GO:0090025) | 2.71882333 |
66 | regulation of nitric oxide biosynthetic process (GO:0045428) | 2.71278844 |
67 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.69451510 |
68 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.67601749 |
69 | sphingolipid catabolic process (GO:0030149) | 2.67241913 |
70 | cellular response to virus (GO:0098586) | 2.66923569 |
71 | positive regulation of interferon-beta production (GO:0032728) | 2.66703241 |
72 | regulation of macrophage cytokine production (GO:0010935) | 2.65835841 |
73 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.64141890 |
74 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.63646779 |
75 | skin morphogenesis (GO:0043589) | 2.63090513 |
76 | germinal center formation (GO:0002467) | 2.61866795 |
77 | substrate-dependent cell migration (GO:0006929) | 2.60076776 |
78 | positive regulation of protein oligomerization (GO:0032461) | 2.59967645 |
79 | stress fiber assembly (GO:0043149) | 2.59060673 |
80 | granulocyte activation (GO:0036230) | 2.58511230 |
81 | COPI coating of Golgi vesicle (GO:0048205) | 2.58305439 |
82 | Golgi transport vesicle coating (GO:0048200) | 2.58305439 |
83 | myeloid cell homeostasis (GO:0002262) | 2.57995512 |
84 | response to laminar fluid shear stress (GO:0034616) | 2.57414750 |
85 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.57178138 |
86 | negative regulation of fatty acid transport (GO:2000192) | 2.56827943 |
87 | regulation of cholesterol storage (GO:0010885) | 2.56675911 |
88 | regulation of podosome assembly (GO:0071801) | 2.55696916 |
89 | negative regulation of lipid storage (GO:0010888) | 2.54967644 |
90 | cellular response to lipopolysaccharide (GO:0071222) | 2.54052017 |
91 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.53860068 |
92 | positive regulation of interleukin-12 production (GO:0032735) | 2.53789557 |
93 | dendritic cell differentiation (GO:0097028) | 2.52671198 |
94 | positive regulation of type 2 immune response (GO:0002830) | 2.52147017 |
95 | NIK/NF-kappaB signaling (GO:0038061) | 2.52002650 |
96 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 2.51498091 |
97 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.51267146 |
98 | macrophage activation involved in immune response (GO:0002281) | 2.49268336 |
99 | T cell apoptotic process (GO:0070231) | 2.48590257 |
100 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 2.48449861 |
101 | eosinophil chemotaxis (GO:0048245) | 2.48275430 |
102 | endocytic recycling (GO:0032456) | 2.48246538 |
103 | regulation of early endosome to late endosome transport (GO:2000641) | 2.46185336 |
104 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.46138307 |
105 | myeloid dendritic cell differentiation (GO:0043011) | 2.45689223 |
106 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.45254015 |
107 | regulation of immunoglobulin secretion (GO:0051023) | 2.45128842 |
108 | establishment of endothelial barrier (GO:0061028) | 2.44807602 |
109 | regulation of heat generation (GO:0031650) | 2.44801241 |
110 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 2.43896391 |
111 | T-helper 1 type immune response (GO:0042088) | 2.43753609 |
112 | pinocytosis (GO:0006907) | 2.43484532 |
113 | amino sugar catabolic process (GO:0046348) | 2.42719743 |
114 | cellular response to molecule of bacterial origin (GO:0071219) | 2.42245653 |
115 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.41779156 |
116 | regulation of antigen processing and presentation (GO:0002577) | 2.41111481 |
117 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.40481391 |
118 | hyaluronan catabolic process (GO:0030214) | 2.39394555 |
119 | basement membrane organization (GO:0071711) | 2.39238237 |
120 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.39103918 |
121 | neutrophil activation (GO:0042119) | 2.38710766 |
122 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.38601988 |
123 | response to magnesium ion (GO:0032026) | 2.37854747 |
124 | negative regulation of viral genome replication (GO:0045071) | 2.37845462 |
125 | myeloid dendritic cell activation (GO:0001773) | 2.37346270 |
126 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.36256032 |
127 | cellular response to arsenic-containing substance (GO:0071243) | 2.36252360 |
128 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.36027089 |
129 | cellular response to vitamin (GO:0071295) | 2.36023966 |
130 | positive regulation of macrophage cytokine production (GO:0060907) | 2.36009930 |
131 | glial cell migration (GO:0008347) | 2.34972021 |
132 | sphingosine metabolic process (GO:0006670) | 2.34882082 |
133 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.34708671 |
134 | B cell mediated immunity (GO:0019724) | 2.33659392 |
135 | response to host immune response (GO:0052572) | 2.33189088 |
136 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.33189088 |
137 | collagen fibril organization (GO:0030199) | 2.33070790 |
138 | regulation of chemokine biosynthetic process (GO:0045073) | 2.32397847 |
139 | response to protozoan (GO:0001562) | 2.32016915 |
140 | hemidesmosome assembly (GO:0031581) | 2.31782816 |
141 | regulation of type 2 immune response (GO:0002828) | 2.31294721 |
142 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.31218078 |
143 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.30337151 |
144 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.29958632 |
145 | chronic inflammatory response (GO:0002544) | 2.29542910 |
146 | membrane raft organization (GO:0031579) | 2.29116939 |
147 | positive regulation of heat generation (GO:0031652) | 2.28860500 |
148 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.28045052 |
149 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.27784463 |
150 | positive regulation of interleukin-6 production (GO:0032755) | 2.27581393 |
151 | regulation of interleukin-6 production (GO:0032675) | 2.27258679 |
152 | positive regulation of leukocyte apoptotic process (GO:2000108) | 2.26999034 |
153 | lymphocyte chemotaxis (GO:0048247) | 2.26575063 |
154 | positive regulation of antigen processing and presentation (GO:0002579) | 2.26569201 |
155 | growth hormone receptor signaling pathway (GO:0060396) | 2.26330033 |
156 | response to vitamin D (GO:0033280) | 2.26046566 |
157 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.24928049 |
158 | modulation by symbiont of host cellular process (GO:0044068) | 2.23601261 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * TP63_17297297_ChIP-ChIP_HaCaT_Human | 7.11700367 |
2 | * TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.91852836 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.85416849 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.81099484 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.60834977 |
6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.57764555 |
7 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.45538497 |
8 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.42306807 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.20636458 |
10 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.06092756 |
11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.78388359 |
12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.47075308 |
13 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.36997431 |
14 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.33250482 |
15 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.31372037 |
16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.29343956 |
17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.28984308 |
18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.22314224 |
19 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.12878759 |
20 | * SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.05026244 |
21 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.00309941 |
22 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.97435676 |
23 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.97105837 |
24 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.95841653 |
25 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.86744273 |
26 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.84625487 |
27 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.84082630 |
28 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.84082630 |
29 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.79058500 |
30 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.74602364 |
31 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.72723140 |
32 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.69133150 |
33 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.65323844 |
34 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.64804696 |
35 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.62189230 |
36 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.57343930 |
37 | * CLOCK_20551151_ChIP-Seq_293T_Human | 1.56558717 |
38 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.55047994 |
39 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.51459558 |
40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.49326884 |
41 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.48436603 |
42 | CJUN_26792858_Chip-Seq_BT549_Human | 1.48230353 |
43 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.46561774 |
44 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.45660648 |
45 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.45293970 |
46 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.44650468 |
47 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.44158978 |
48 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.42178480 |
49 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.39373917 |
50 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.38030024 |
51 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.37365884 |
52 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.36460457 |
53 | MAF_26560356_Chip-Seq_TH1_Human | 1.35650737 |
54 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.33762253 |
55 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32127069 |
56 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.31687587 |
57 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31637692 |
58 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.31034041 |
59 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.28219041 |
60 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.27455367 |
61 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.26805454 |
62 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.26197090 |
63 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.23466552 |
64 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.22222569 |
65 | * PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.19070810 |
66 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.18932804 |
67 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.18700421 |
68 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.18273903 |
69 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.18105668 |
70 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.17861321 |
71 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.16723624 |
72 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16512826 |
73 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.15362154 |
74 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.15286597 |
75 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.15046378 |
76 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.14926364 |
77 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.11079326 |
78 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.11011765 |
79 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.10824503 |
80 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.10774431 |
81 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.09842383 |
82 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.09746459 |
83 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.08371282 |
84 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.07699789 |
85 | * STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.07602956 |
86 | * PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.07073451 |
87 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07052323 |
88 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.06955648 |
89 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06827728 |
90 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.05177178 |
91 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.04667317 |
92 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.04516380 |
93 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.04153489 |
94 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.04060783 |
95 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.03667760 |
96 | MYB_26560356_Chip-Seq_TH2_Human | 1.02382531 |
97 | SPI1_23127762_ChIP-Seq_K562_Human | 1.02182218 |
98 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.02133404 |
99 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.01862056 |
100 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.01142758 |
101 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.99756813 |
102 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.99304865 |
103 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.99125201 |
104 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.99031039 |
105 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.99021903 |
106 | * TP53_22127205_ChIP-Seq_IMR90_Human | 0.98417094 |
107 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.97938914 |
108 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97934378 |
109 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.97885378 |
110 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.97885378 |
111 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.97554661 |
112 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.97018483 |
113 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96084761 |
114 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.94621011 |
115 | GATA1_19941826_ChIP-Seq_K562_Human | 0.94129333 |
116 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93736045 |
117 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.92126707 |
118 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.92046769 |
119 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.91214660 |
120 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.89989469 |
121 | UTX_26944678_Chip-Seq_JUKART_Human | 0.88919696 |
122 | MYB_26560356_Chip-Seq_TH1_Human | 0.87438454 |
123 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 0.86784188 |
124 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.85997529 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 3.47178260 |
2 | MP0003303_peritoneal_inflammation | 3.19769971 |
3 | MP0003705_abnormal_hypodermis_morpholog | 2.76995823 |
4 | MP0005275_abnormal_skin_tensile | 2.73712618 |
5 | MP0003566_abnormal_cell_adhesion | 2.66540720 |
6 | * MP0003436_decreased_susceptibility_to | 2.45216603 |
7 | MP0002148_abnormal_hypersensitivity_rea | 2.43541151 |
8 | MP0010352_gastrointestinal_tract_polyps | 2.43261470 |
9 | MP0005451_abnormal_body_composition | 2.42630361 |
10 | MP0009785_altered_susceptibility_to | 2.28794468 |
11 | MP0001835_abnormal_antigen_presentation | 2.17291122 |
12 | MP0006082_CNS_inflammation | 2.14749891 |
13 | MP0003448_altered_tumor_morphology | 2.11495319 |
14 | MP0002139_abnormal_hepatobiliary_system | 2.07783668 |
15 | MP0005076_abnormal_cell_differentiation | 2.00390889 |
16 | MP0000685_abnormal_immune_system | 2.00306270 |
17 | MP0003091_abnormal_cell_migration | 1.99178092 |
18 | MP0005023_abnormal_wound_healing | 1.96428247 |
19 | MP0002877_abnormal_melanocyte_morpholog | 1.96123731 |
20 | MP0003300_gastrointestinal_ulcer | 1.95922730 |
21 | * MP0001533_abnormal_skeleton_physiology | 1.94071684 |
22 | MP0004510_myositis | 1.93858248 |
23 | MP0005623_abnormal_meninges_morphology | 1.92558055 |
24 | MP0005503_abnormal_tendon_morphology | 1.91420151 |
25 | MP0008004_abnormal_stomach_pH | 1.86559369 |
26 | MP0004947_skin_inflammation | 1.85792017 |
27 | * MP0005000_abnormal_immune_tolerance | 1.82528779 |
28 | MP0005058_abnormal_lysosome_morphology | 1.80097746 |
29 | MP0005387_immune_system_phenotype | 1.79997546 |
30 | MP0001790_abnormal_immune_system | 1.79997546 |
31 | MP0000604_amyloidosis | 1.78065871 |
32 | MP0003279_aneurysm | 1.77203516 |
33 | MP0003724_increased_susceptibility_to | 1.77123694 |
34 | * MP0002419_abnormal_innate_immunity | 1.73567797 |
35 | MP0009278_abnormal_bone_marrow | 1.69959786 |
36 | MP0003191_abnormal_cellular_cholesterol | 1.65991644 |
37 | MP0005025_abnormal_response_to | 1.62534820 |
38 | MP0000343_altered_response_to | 1.61383003 |
39 | MP0005257_abnormal_intraocular_pressure | 1.61379519 |
40 | * MP0003453_abnormal_keratinocyte_physiol | 1.60332630 |
41 | MP0002254_reproductive_system_inflammat | 1.58605150 |
42 | * MP0000858_altered_metastatic_potential | 1.54844266 |
43 | * MP0002452_abnormal_antigen_presenting | 1.54741618 |
44 | * MP0005390_skeleton_phenotype | 1.51309680 |
45 | * MP0000733_abnormal_muscle_development | 1.50910065 |
46 | MP0001348_abnormal_lacrimal_gland | 1.47975973 |
47 | MP0002405_respiratory_system_inflammati | 1.45772168 |
48 | MP0003828_pulmonary_edema | 1.44826136 |
49 | MP0004272_abnormal_basement_membrane | 1.43973903 |
50 | MP0001958_emphysema | 1.41998334 |
51 | MP0002332_abnormal_exercise_endurance | 1.41408459 |
52 | MP0002998_abnormal_bone_remodeling | 1.41399085 |
53 | MP0002060_abnormal_skin_morphology | 1.40943273 |
54 | MP0002933_joint_inflammation | 1.33051113 |
55 | MP0002796_impaired_skin_barrier | 1.32478966 |
56 | MP0000750_abnormal_muscle_regeneration | 1.31566351 |
57 | * MP0001542_abnormal_bone_strength | 1.30143390 |
58 | * MP0002723_abnormal_immune_serum | 1.29971687 |
59 | MP0009333_abnormal_splenocyte_physiolog | 1.29857141 |
60 | MP0001853_heart_inflammation | 1.27735297 |
61 | * MP0001800_abnormal_humoral_immune | 1.26161395 |
62 | MP0003329_amyloid_beta_deposits | 1.21500347 |
63 | * MP0010155_abnormal_intestine_physiology | 1.19990960 |
64 | MP0003045_fibrosis | 1.17747219 |
65 | * MP0001819_abnormal_immune_cell | 1.17226076 |
66 | MP0000767_abnormal_smooth_muscle | 1.16544739 |
67 | MP0005671_abnormal_response_to | 1.14092550 |
68 | * MP0002420_abnormal_adaptive_immunity | 1.13137852 |
69 | MP0002006_tumorigenesis | 1.13054502 |
70 | * MP0005508_abnormal_skeleton_morphology | 1.12831108 |
71 | MP0006054_spinal_hemorrhage | 1.09476463 |
72 | MP0001243_abnormal_dermal_layer | 1.08828648 |
73 | * MP0001845_abnormal_inflammatory_respons | 1.07129693 |
74 | MP0003656_abnormal_erythrocyte_physiolo | 1.05528547 |
75 | MP0008260_abnormal_autophagy | 1.05454215 |
76 | MP0005595_abnormal_vascular_smooth | 1.04943778 |
77 | MP0001216_abnormal_epidermal_layer | 1.04925619 |
78 | MP0001849_ear_inflammation | 1.04596128 |
79 | MP0005167_abnormal_blood-brain_barrier | 0.99928853 |
80 | MP0009840_abnormal_foam_cell | 0.99647892 |
81 | MP0005464_abnormal_platelet_physiology | 0.99387840 |
82 | MP0002295_abnormal_pulmonary_circulatio | 0.99244073 |
83 | MP0010234_abnormal_vibrissa_follicle | 0.97848874 |
84 | MP0003795_abnormal_bone_structure | 0.97736078 |
85 | MP0001851_eye_inflammation | 0.97485261 |
86 | MP0002166_altered_tumor_susceptibility | 0.91930983 |
87 | * MP0005164_abnormal_response_to | 0.91651585 |
88 | MP0010030_abnormal_orbit_morphology | 0.89970513 |
89 | * MP0005501_abnormal_skin_physiology | 0.87352684 |
90 | MP0001915_intracranial_hemorrhage | 0.85516509 |
91 | MP0003075_altered_response_to | 0.84753737 |
92 | MP0001346_abnormal_lacrimal_gland | 0.84230889 |
93 | * MP0009764_decreased_sensitivity_to | 0.83832187 |
94 | MP0002138_abnormal_hepatobiliary_system | 0.82137115 |
95 | MP0008469_abnormal_protein_level | 0.82033623 |
96 | MP0009384_cardiac_valve_regurgitation | 0.81993146 |
97 | MP0000249_abnormal_blood_vessel | 0.81901305 |
98 | MP0004883_abnormal_blood_vessel | 0.81737463 |
99 | * MP0001545_abnormal_hematopoietic_system | 0.81242555 |
100 | * MP0005397_hematopoietic_system_phenotyp | 0.81242555 |
101 | MP0004858_abnormal_nervous_system | 0.80815770 |
102 | * MP0009763_increased_sensitivity_to | 0.78121982 |
103 | MP0005310_abnormal_salivary_gland | 0.77551759 |
104 | MP0003172_abnormal_lysosome_physiology | 0.76905347 |
105 | MP0002896_abnormal_bone_mineralization | 0.76399444 |
106 | MP0005166_decreased_susceptibility_to | 0.75744251 |
107 | * MP0000627_abnormal_mammary_gland | 0.75514037 |
108 | MP0002277_abnormal_respiratory_mucosa | 0.74458365 |
109 | MP0003950_abnormal_plasma_membrane | 0.74085900 |
110 | MP0003634_abnormal_glial_cell | 0.72997610 |
111 | * MP0000716_abnormal_immune_system | 0.72848471 |
112 | * MP0010307_abnormal_tumor_latency | 0.72254083 |
113 | MP0009931_abnormal_skin_appearance | 0.71075212 |
114 | * MP0002113_abnormal_skeleton_development | 0.70864374 |
115 | MP0005165_increased_susceptibility_to | 0.69616229 |
116 | MP0000920_abnormal_myelination | 0.69475551 |
117 | MP0003183_abnormal_peptide_metabolism | 0.66896803 |
118 | * MP0008874_decreased_physiological_sensi | 0.66699875 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of glycolipid metabolism (HP:0010969) | 5.92142318 |
2 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.92142318 |
3 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.92142318 |
4 | Premature rupture of membranes (HP:0001788) | 4.78948445 |
5 | Protrusio acetabuli (HP:0003179) | 4.36600067 |
6 | Eczematoid dermatitis (HP:0000976) | 3.88930944 |
7 | Systemic lupus erythematosus (HP:0002725) | 3.76967637 |
8 | Loss of speech (HP:0002371) | 3.72635368 |
9 | Vertebral compression fractures (HP:0002953) | 3.66137114 |
10 | Nuclear cataract (HP:0100018) | 3.52167289 |
11 | Peritonitis (HP:0002586) | 3.49313743 |
12 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.30919546 |
13 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.30919546 |
14 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.30919546 |
15 | Mucopolysacchariduria (HP:0008155) | 3.28604132 |
16 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.28604132 |
17 | Recurrent abscess formation (HP:0002722) | 3.20794309 |
18 | Neurofibrillary tangles (HP:0002185) | 3.03269010 |
19 | Atrophic scars (HP:0001075) | 2.93662153 |
20 | Recurrent bacterial skin infections (HP:0005406) | 2.92484501 |
21 | Autoimmune thrombocytopenia (HP:0001973) | 2.84982903 |
22 | Cervical subluxation (HP:0003308) | 2.79885969 |
23 | Aplasia of the musculature (HP:0100854) | 2.76783584 |
24 | Disinhibition (HP:0000734) | 2.74008350 |
25 | Popliteal pterygium (HP:0009756) | 2.66780084 |
26 | Ulnar deviation of the wrist (HP:0003049) | 2.64405919 |
27 | Osteolytic defects of the hand bones (HP:0009699) | 2.64063253 |
28 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.64063253 |
29 | Round ear (HP:0100830) | 2.63148367 |
30 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63139404 |
31 | Increased cerebral lipofuscin (HP:0011813) | 2.62331615 |
32 | Increased connective tissue (HP:0009025) | 2.61276003 |
33 | Orchitis (HP:0100796) | 2.60849774 |
34 | Distal arthrogryposis (HP:0005684) | 2.56684811 |
35 | Spondylolisthesis (HP:0003302) | 2.54034338 |
36 | Thin bony cortex (HP:0002753) | 2.50135484 |
37 | Thick nail (HP:0001805) | 2.49637644 |
38 | Vacuolated lymphocytes (HP:0001922) | 2.49460222 |
39 | Myocardial infarction (HP:0001658) | 2.47528870 |
40 | Myositis (HP:0100614) | 2.47284825 |
41 | Abnormality of macrophages (HP:0004311) | 2.46727849 |
42 | Type 1 muscle fiber predominance (HP:0003803) | 2.45033033 |
43 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.44139994 |
44 | Cerebral aneurysm (HP:0004944) | 2.43607520 |
45 | Distal lower limb muscle weakness (HP:0009053) | 2.39786102 |
46 | Aortic dissection (HP:0002647) | 2.38762247 |
47 | Achilles tendon contracture (HP:0001771) | 2.38274261 |
48 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.37429082 |
49 | Trismus (HP:0000211) | 2.36488610 |
50 | Fragile skin (HP:0001030) | 2.36032601 |
51 | Apathy (HP:0000741) | 2.35874050 |
52 | Cerebral inclusion bodies (HP:0100314) | 2.35578821 |
53 | Right ventricular cardiomyopathy (HP:0011663) | 2.34097122 |
54 | Tetraparesis (HP:0002273) | 2.33710907 |
55 | Mutism (HP:0002300) | 2.33320583 |
56 | Prolonged neonatal jaundice (HP:0006579) | 2.32417153 |
57 | Distal lower limb amyotrophy (HP:0008944) | 2.32142215 |
58 | Spinal rigidity (HP:0003306) | 2.31576938 |
59 | Dilatation of the ascending aorta (HP:0005111) | 2.30740783 |
60 | Cupped ribs (HP:0000887) | 2.30225302 |
61 | Purpura (HP:0000979) | 2.30096977 |
62 | Pterygium (HP:0001059) | 2.29406535 |
63 | Malignant hyperthermia (HP:0002047) | 2.27751322 |
64 | Follicular hyperkeratosis (HP:0007502) | 2.27733666 |
65 | Difficulty climbing stairs (HP:0003551) | 2.26629254 |
66 | Interstitial pulmonary disease (HP:0006530) | 2.26159268 |
67 | Shallow orbits (HP:0000586) | 2.23965670 |
68 | Diminished motivation (HP:0000745) | 2.23603461 |
69 | Distal upper limb amyotrophy (HP:0007149) | 2.21480097 |
70 | Upper limb amyotrophy (HP:0009129) | 2.21480097 |
71 | Glomerulonephritis (HP:0000099) | 2.21005814 |
72 | Abnormality of the Achilles tendon (HP:0005109) | 2.19043037 |
73 | Asymmetric septal hypertrophy (HP:0001670) | 2.18727861 |
74 | Nemaline bodies (HP:0003798) | 2.16379652 |
75 | Progressive neurologic deterioration (HP:0002344) | 2.15754104 |
76 | Mediastinal lymphadenopathy (HP:0100721) | 2.15459387 |
77 | Muscle fiber inclusion bodies (HP:0100299) | 2.15443243 |
78 | Aortic aneurysm (HP:0004942) | 2.15302320 |
79 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.14852311 |
80 | Axonal loss (HP:0003447) | 2.14404832 |
81 | Pustule (HP:0200039) | 2.11518264 |
82 | Short nail (HP:0001799) | 2.08342875 |
83 | Abnormality of placental membranes (HP:0011409) | 2.08320679 |
84 | Amniotic constriction ring (HP:0009775) | 2.08320679 |
85 | Breech presentation (HP:0001623) | 2.08082172 |
86 | Increased density of long bones (HP:0006392) | 2.07843420 |
87 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.06334316 |
88 | Soft skin (HP:0000977) | 2.05679668 |
89 | Vascular tortuosity (HP:0004948) | 2.03480654 |
90 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.03328896 |
91 | Calcaneovalgus deformity (HP:0001848) | 2.03037358 |
92 | Wormian bones (HP:0002645) | 2.02720404 |
93 | Upper motor neuron abnormality (HP:0002127) | 2.01308258 |
94 | Mitral stenosis (HP:0001718) | 2.01280681 |
95 | Blue sclerae (HP:0000592) | 2.01201118 |
96 | Absent phalangeal crease (HP:0006109) | 2.00687845 |
97 | Coxa vara (HP:0002812) | 1.99698905 |
98 | Increased IgM level (HP:0003496) | 1.98946600 |
99 | Bladder diverticulum (HP:0000015) | 1.98835789 |
100 | Fused cervical vertebrae (HP:0002949) | 1.98568084 |
101 | Hematochezia (HP:0002573) | 1.97880355 |
102 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.97289617 |
103 | Genu recurvatum (HP:0002816) | 1.97179242 |
104 | Neuronal loss in central nervous system (HP:0002529) | 1.96338914 |
105 | Myopathic facies (HP:0002058) | 1.95622288 |
106 | Amyloidosis (HP:0011034) | 1.95528793 |
107 | Emphysema (HP:0002097) | 1.95465915 |
108 | Bone pain (HP:0002653) | 1.93715606 |
109 | Entropion (HP:0000621) | 1.91255583 |
110 | Long toe (HP:0010511) | 1.90829488 |
111 | Hip contracture (HP:0003273) | 1.89810891 |
112 | Hydroxyprolinuria (HP:0003080) | 1.89342274 |
113 | Abnormality of proline metabolism (HP:0010907) | 1.89342274 |
114 | Abnormality of the pericardium (HP:0001697) | 1.88577314 |
115 | Alopecia of scalp (HP:0002293) | 1.88543489 |
116 | Thin ribs (HP:0000883) | 1.88033695 |
117 | Malnutrition (HP:0004395) | 1.87311912 |
118 | Ovoid vertebral bodies (HP:0003300) | 1.86960705 |
119 | Optic neuritis (HP:0100653) | 1.86076883 |
120 | Retrobulbar optic neuritis (HP:0100654) | 1.86076883 |
121 | Cellulitis (HP:0100658) | 1.85565624 |
122 | Dysostosis multiplex (HP:0000943) | 1.85024029 |
123 | Gingivitis (HP:0000230) | 1.84000177 |
124 | Abnormal delivery (HP:0001787) | 1.82555738 |
125 | Arterial tortuosity (HP:0005116) | 1.82116307 |
126 | Metaphyseal irregularity (HP:0003025) | 1.82058657 |
127 | Biconcave vertebral bodies (HP:0004586) | 1.82028000 |
128 | Abnormality of the acetabulum (HP:0003170) | 1.81631959 |
129 | Hypergammaglobulinemia (HP:0010702) | 1.81418548 |
130 | Abnormality of the neuromuscular junction (HP:0003398) | 1.81263407 |
131 | Fatigable weakness (HP:0003473) | 1.81263407 |
132 | Deformed tarsal bones (HP:0008119) | 1.80384072 |
133 | Joint stiffness (HP:0001387) | 1.80177215 |
134 | Abnormality of complement system (HP:0005339) | 1.79833750 |
135 | Hand muscle atrophy (HP:0009130) | 1.79437259 |
136 | Petechiae (HP:0000967) | 1.79417387 |
137 | Abnormality of the calcaneus (HP:0008364) | 1.79277792 |
138 | Increased serum ferritin (HP:0003281) | 1.78518843 |
139 | Flat acetabular roof (HP:0003180) | 1.78485786 |
140 | Recurrent fungal infections (HP:0002841) | 1.78304942 |
141 | Muscle fiber splitting (HP:0003555) | 1.78302350 |
142 | Natal tooth (HP:0000695) | 1.78301041 |
143 | J-shaped sella turcica (HP:0002680) | 1.78082257 |
144 | Ankle contracture (HP:0006466) | 1.78075330 |
145 | Complement deficiency (HP:0004431) | 1.77201466 |
146 | Parakeratosis (HP:0001036) | 1.76829189 |
147 | Mitral regurgitation (HP:0001653) | 1.76568317 |
148 | Porencephaly (HP:0002132) | 1.76507678 |
149 | Increased IgE level (HP:0003212) | 1.76027288 |
150 | Aneurysm (HP:0002617) | 1.75918193 |
151 | Basal ganglia calcification (HP:0002135) | 1.75634727 |
152 | Protuberant abdomen (HP:0001538) | 1.73863934 |
153 | Femoral bowing (HP:0002980) | 1.73551354 |
154 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.69345812 |
155 | Hepatosplenomegaly (HP:0001433) | 1.66883903 |
156 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.66566889 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.08924233 |
2 | TBK1 | 3.04308522 |
3 | ERN1 | 2.96072689 |
4 | MAP3K14 | 2.93178785 |
5 | GRK7 | 2.74368034 |
6 | DDR2 | 2.58126482 |
7 | TESK1 | 2.55105982 |
8 | PRPF4B | 2.40705742 |
9 | IKBKB | 2.16827325 |
10 | PBK | 2.15793847 |
11 | EPHA2 | 2.06670609 |
12 | BMX | 2.05523834 |
13 | MOS | 1.98820824 |
14 | MAP3K3 | 1.96521095 |
15 | TYK2 | 1.95061215 |
16 | BLK | 1.91728499 |
17 | IRAK3 | 1.86814954 |
18 | CHUK | 1.85463588 |
19 | NME2 | 1.84842655 |
20 | EPHB1 | 1.84621560 |
21 | IKBKE | 1.72614948 |
22 | NEK9 | 1.71965949 |
23 | CDC42BPA | 1.65831274 |
24 | RIPK1 | 1.61433768 |
25 | LIMK1 | 1.56923614 |
26 | EPHA3 | 1.53852105 |
27 | LRRK2 | 1.51839596 |
28 | MYLK | 1.50654500 |
29 | MAP3K11 | 1.49340348 |
30 | RPS6KA4 | 1.48520799 |
31 | TESK2 | 1.48508738 |
32 | JAK3 | 1.46356682 |
33 | PAK4 | 1.39397084 |
34 | STK10 | 1.38991295 |
35 | TRPM7 | 1.37096064 |
36 | PIK3CG | 1.30068315 |
37 | JAK1 | 1.29717112 |
38 | IRAK4 | 1.27998325 |
39 | MST4 | 1.27191278 |
40 | TTN | 1.26035228 |
41 | PKN2 | 1.24019127 |
42 | CSK | 1.22149055 |
43 | ABL2 | 1.19651312 |
44 | MAPKAPK3 | 1.18726401 |
45 | RIPK4 | 1.18405365 |
46 | PTK6 | 1.16819054 |
47 | FER | 1.16204302 |
48 | PDGFRA | 1.11270356 |
49 | EPHB2 | 1.07914095 |
50 | ICK | 1.07732141 |
51 | TAOK1 | 1.04982639 |
52 | PTK2 | 1.03259683 |
53 | SIK3 | 1.02814360 |
54 | TGFBR2 | 1.00327547 |
55 | KIT | 1.00318286 |
56 | MATK | 0.94931286 |
57 | PRKD2 | 0.94718081 |
58 | MAP3K1 | 0.93792151 |
59 | DMPK | 0.93567241 |
60 | MST1R | 0.91505218 |
61 | MAPKAPK2 | 0.91380701 |
62 | PAK2 | 0.90384812 |
63 | FGFR3 | 0.89461296 |
64 | STK3 | 0.89051997 |
65 | LATS2 | 0.88024954 |
66 | FGFR4 | 0.83745702 |
67 | BMPR2 | 0.83557224 |
68 | TAOK2 | 0.83484742 |
69 | * PIM1 | 0.82477171 |
70 | HCK | 0.80139354 |
71 | MAP4K1 | 0.78547839 |
72 | LATS1 | 0.78289609 |
73 | MAP2K1 | 0.77820419 |
74 | NTRK1 | 0.77418830 |
75 | SMG1 | 0.76486035 |
76 | MAP2K3 | 0.76180961 |
77 | AKT3 | 0.72327253 |
78 | ADRBK2 | 0.71919575 |
79 | ZAP70 | 0.71808289 |
80 | PRKG2 | 0.70849112 |
81 | MAP2K2 | 0.69841403 |
82 | CDK12 | 0.69401486 |
83 | RPS6KA2 | 0.69346185 |
84 | MAP3K13 | 0.68617737 |
85 | ILK | 0.67887206 |
86 | KDR | 0.67707294 |
87 | EGFR | 0.66530257 |
88 | CSF1R | 0.66086135 |
89 | FGR | 0.59887230 |
90 | * ABL1 | 0.59212930 |
91 | MAP3K10 | 0.57368412 |
92 | MAP3K8 | 0.56825175 |
93 | ERBB4 | 0.56483501 |
94 | EIF2AK2 | 0.55211120 |
95 | PTK2B | 0.55143846 |
96 | RPS6KC1 | 0.54937387 |
97 | RPS6KL1 | 0.54937387 |
98 | IRAK2 | 0.52614651 |
99 | CLK1 | 0.50797372 |
100 | PDGFRB | 0.50564858 |
101 | STK4 | 0.49844478 |
102 | HIPK2 | 0.49720412 |
103 | * PIM2 | 0.49534641 |
104 | JAK2 | 0.49378992 |
105 | CDK9 | 0.48805199 |
106 | LCK | 0.48768336 |
107 | LMTK2 | 0.47475975 |
108 | PDPK1 | 0.47246367 |
109 | ALK | 0.46605596 |
110 | TAOK3 | 0.46185145 |
111 | TYRO3 | 0.46130355 |
112 | SIK1 | 0.45916512 |
113 | EEF2K | 0.45180915 |
114 | * DAPK3 | 0.44993489 |
115 | MAPK7 | 0.44888302 |
116 | PAK1 | 0.44694297 |
117 | GSK3A | 0.44537327 |
118 | ROCK2 | 0.43957099 |
119 | MET | 0.43797142 |
120 | STK24 | 0.43483414 |
121 | CAMK2G | 0.42599208 |
122 | ARAF | 0.41306675 |
123 | IRAK1 | 0.40625861 |
124 | MTOR | 0.40341400 |
125 | MARK3 | 0.39743067 |
126 | ERBB3 | 0.39339235 |
127 | TGFBR1 | 0.38863521 |
128 | ROCK1 | 0.37480201 |
129 | PRKCD | 0.37326525 |
130 | INSR | 0.36707616 |
131 | RPS6KA6 | 0.36001695 |
132 | DYRK3 | 0.29964588 |
133 | MARK2 | 0.29313074 |
134 | * MAP3K5 | 0.29172752 |
135 | STK38 | 0.28694011 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.61638177 |
2 | Malaria_Homo sapiens_hsa05144 | 2.23715899 |
3 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.18776468 |
4 | Allograft rejection_Homo sapiens_hsa05330 | 1.99769656 |
5 | Legionellosis_Homo sapiens_hsa05134 | 1.97114147 |
6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.96908172 |
7 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.96677112 |
8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.93336136 |
9 | Shigellosis_Homo sapiens_hsa05131 | 1.90700885 |
10 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.89152612 |
11 | Pertussis_Homo sapiens_hsa05133 | 1.83716127 |
12 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.81511367 |
13 | Apoptosis_Homo sapiens_hsa04210 | 1.77387214 |
14 | Viral myocarditis_Homo sapiens_hsa05416 | 1.74167234 |
15 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.72958789 |
16 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.68552273 |
17 | Salmonella infection_Homo sapiens_hsa05132 | 1.68101982 |
18 | Measles_Homo sapiens_hsa05162 | 1.67782833 |
19 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.66593194 |
20 | Tuberculosis_Homo sapiens_hsa05152 | 1.66547507 |
21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64892148 |
22 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.62887484 |
23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.62702939 |
24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.61492862 |
25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.59229836 |
26 | * p53 signaling pathway_Homo sapiens_hsa04115 | 1.57248566 |
27 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.54538088 |
28 | Influenza A_Homo sapiens_hsa05164 | 1.49676758 |
29 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.46845576 |
30 | Phagosome_Homo sapiens_hsa04145 | 1.46557749 |
31 | Lysosome_Homo sapiens_hsa04142 | 1.45596283 |
32 | Amoebiasis_Homo sapiens_hsa05146 | 1.44767508 |
33 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.38200307 |
34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.36458595 |
35 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.33116824 |
36 | Focal adhesion_Homo sapiens_hsa04510 | 1.32905069 |
37 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.31440550 |
38 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.28565173 |
39 | Adherens junction_Homo sapiens_hsa04520 | 1.27914753 |
40 | * Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.25271865 |
41 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.23688203 |
42 | * Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.21175661 |
43 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.19733426 |
44 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.19553763 |
45 | Asthma_Homo sapiens_hsa05310 | 1.18361159 |
46 | * Hepatitis B_Homo sapiens_hsa05161 | 1.17451684 |
47 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.16429425 |
48 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.15480162 |
49 | * Bladder cancer_Homo sapiens_hsa05219 | 1.09566805 |
50 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.05760428 |
51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.05141370 |
52 | * MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.02896076 |
53 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.02092045 |
54 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.00063056 |
55 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.99544003 |
56 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.98702983 |
57 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.98556421 |
58 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.98037761 |
59 | * Hepatitis C_Homo sapiens_hsa05160 | 0.96184655 |
60 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.95691058 |
61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.93648078 |
62 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.92814843 |
63 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.91796277 |
64 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.90651047 |
65 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.90559485 |
66 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89619117 |
67 | Galactose metabolism_Homo sapiens_hsa00052 | 0.88715073 |
68 | Other glycan degradation_Homo sapiens_hsa00511 | 0.87173174 |
69 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.85894923 |
70 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.85768305 |
71 | * HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.84275752 |
72 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.82212645 |
73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.80994468 |
74 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76687882 |
75 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.76265726 |
76 | Platelet activation_Homo sapiens_hsa04611 | 0.75840724 |
77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74995774 |
78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74647392 |
79 | * HTLV-I infection_Homo sapiens_hsa05166 | 0.74003600 |
80 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.73114036 |
81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.71161534 |
82 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 0.69835376 |
83 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.69789880 |
84 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.68913830 |
85 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.68295969 |
86 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.67192917 |
87 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.66038740 |
88 | Mineral absorption_Homo sapiens_hsa04978 | 0.65764374 |
89 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64434894 |
90 | Endocytosis_Homo sapiens_hsa04144 | 0.62591495 |
91 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.60702566 |
92 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.59780014 |
93 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59236529 |
94 | Tight junction_Homo sapiens_hsa04530 | 0.58423168 |
95 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57481230 |
96 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.57444475 |
97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.56093626 |
98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.55264829 |
99 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.54895014 |
100 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.54663113 |
101 | * Pathways in cancer_Homo sapiens_hsa05200 | 0.53091529 |
102 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.52590048 |
103 | * Prostate cancer_Homo sapiens_hsa05215 | 0.51941077 |
104 | * Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.50823822 |
105 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48788342 |
106 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.47528844 |
107 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.47063185 |
108 | Prion diseases_Homo sapiens_hsa05020 | 0.45967906 |
109 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.45268658 |
110 | * Melanoma_Homo sapiens_hsa05218 | 0.44801733 |
111 | Insulin resistance_Homo sapiens_hsa04931 | 0.44594728 |
112 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.43117515 |
113 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.42490424 |
114 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.42407483 |
115 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.36332839 |
116 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.33471135 |
117 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33256837 |