Rank | Gene Set | Z-score |
---|---|---|
1 | synapsis (GO:0007129) | 5.34571184 |
2 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 4.40609218 |
3 | DNA deamination (GO:0045006) | 4.24907295 |
4 | ribosomal small subunit assembly (GO:0000028) | 4.10442929 |
5 | sperm-egg recognition (GO:0035036) | 3.95933624 |
6 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.89441728 |
7 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 3.84349512 |
8 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.80040613 |
9 | nuclear pore complex assembly (GO:0051292) | 3.78502283 |
10 | cell wall macromolecule metabolic process (GO:0044036) | 3.68361488 |
11 | cell wall macromolecule catabolic process (GO:0016998) | 3.68361488 |
12 | piRNA metabolic process (GO:0034587) | 3.68191733 |
13 | acrosome assembly (GO:0001675) | 3.67453889 |
14 | binding of sperm to zona pellucida (GO:0007339) | 3.64518768 |
15 | pyrimidine dimer repair (GO:0006290) | 3.61081126 |
16 | centriole replication (GO:0007099) | 3.53385450 |
17 | sperm motility (GO:0030317) | 3.51211651 |
18 | multicellular organism reproduction (GO:0032504) | 3.51105916 |
19 | cell-cell recognition (GO:0009988) | 3.49363628 |
20 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.49161560 |
21 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.49161560 |
22 | negative regulation of sister chromatid segregation (GO:0033046) | 3.49161560 |
23 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.49161560 |
24 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.49161560 |
25 | negative regulation of meiosis (GO:0045835) | 3.44225729 |
26 | dosage compensation (GO:0007549) | 3.42893444 |
27 | mitotic spindle assembly checkpoint (GO:0007094) | 3.42595419 |
28 | spindle assembly checkpoint (GO:0071173) | 3.41126596 |
29 | DNA methylation involved in gamete generation (GO:0043046) | 3.38170808 |
30 | negative regulation of chromosome segregation (GO:0051985) | 3.37555669 |
31 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.36098059 |
32 | mitotic spindle checkpoint (GO:0071174) | 3.35757073 |
33 | protein localization to chromosome (GO:0034502) | 3.34117582 |
34 | histone mRNA catabolic process (GO:0071044) | 3.34106747 |
35 | regulation of chromatin binding (GO:0035561) | 3.33202049 |
36 | male meiosis (GO:0007140) | 3.28211429 |
37 | histone H2A acetylation (GO:0043968) | 3.26176534 |
38 | definitive hemopoiesis (GO:0060216) | 3.25474479 |
39 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.23277301 |
40 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.22660112 |
41 | regulation of centriole replication (GO:0046599) | 3.21619521 |
42 | pore complex assembly (GO:0046931) | 3.19759500 |
43 | chromatin remodeling at centromere (GO:0031055) | 3.19544191 |
44 | CENP-A containing nucleosome assembly (GO:0034080) | 3.18541808 |
45 | viral mRNA export from host cell nucleus (GO:0046784) | 3.18288706 |
46 | axonemal dynein complex assembly (GO:0070286) | 3.18124207 |
47 | spindle checkpoint (GO:0031577) | 3.15791968 |
48 | telomere maintenance via recombination (GO:0000722) | 3.13376824 |
49 | kinetochore organization (GO:0051383) | 3.12942693 |
50 | histone exchange (GO:0043486) | 3.12484216 |
51 | negative regulation of DNA recombination (GO:0045910) | 3.09120125 |
52 | meiotic cell cycle process (GO:1903046) | 3.09052899 |
53 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.08655395 |
54 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.08655395 |
55 | regulation of helicase activity (GO:0051095) | 3.07770812 |
56 | spermatid development (GO:0007286) | 3.06440620 |
57 | regulation of sister chromatid segregation (GO:0033045) | 3.06410335 |
58 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.06410335 |
59 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.06410335 |
60 | DNA replication initiation (GO:0006270) | 3.04663666 |
61 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.04501094 |
62 | protein K6-linked ubiquitination (GO:0085020) | 2.99742728 |
63 | regulation of DNA endoreduplication (GO:0032875) | 2.96907821 |
64 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.95361972 |
65 | mitotic chromosome condensation (GO:0007076) | 2.94064750 |
66 | centriole assembly (GO:0098534) | 2.93999597 |
67 | mitotic metaphase plate congression (GO:0007080) | 2.93924184 |
68 | positive regulation of mitochondrial fission (GO:0090141) | 2.93309625 |
69 | mitotic recombination (GO:0006312) | 2.93259974 |
70 | spermatid nucleus differentiation (GO:0007289) | 2.92442272 |
71 | meiotic chromosome segregation (GO:0045132) | 2.91550264 |
72 | DNA strand elongation (GO:0022616) | 2.89841855 |
73 | base-excision repair, AP site formation (GO:0006285) | 2.89380589 |
74 | maturation of SSU-rRNA (GO:0030490) | 2.84958860 |
75 | synaptonemal complex assembly (GO:0007130) | 2.84834577 |
76 | synaptonemal complex organization (GO:0070193) | 2.84154917 |
77 | histone H3-K9 methylation (GO:0051567) | 2.84013246 |
78 | metaphase plate congression (GO:0051310) | 2.83118704 |
79 | positive regulation of granulocyte differentiation (GO:0030854) | 2.83038285 |
80 | kinetochore assembly (GO:0051382) | 2.82515880 |
81 | chromosome organization involved in meiosis (GO:0070192) | 2.81006021 |
82 | reproduction (GO:0000003) | 2.80687287 |
83 | male meiosis I (GO:0007141) | 2.80305886 |
84 | iron-sulfur cluster assembly (GO:0016226) | 2.79035750 |
85 | metallo-sulfur cluster assembly (GO:0031163) | 2.79035750 |
86 | tRNA methylation (GO:0030488) | 2.78575384 |
87 | DNA replication-independent nucleosome organization (GO:0034724) | 2.78389913 |
88 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.78389913 |
89 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.78282689 |
90 | histone mRNA metabolic process (GO:0008334) | 2.76557428 |
91 | regulation of chromosome segregation (GO:0051983) | 2.75537113 |
92 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.74590409 |
93 | meiotic nuclear division (GO:0007126) | 2.74091800 |
94 | microtubule depolymerization (GO:0007019) | 2.73264570 |
95 | plasma membrane fusion (GO:0045026) | 2.72905786 |
96 | negative regulation of nuclear division (GO:0051784) | 2.72626715 |
97 | peptidyl-lysine trimethylation (GO:0018023) | 2.70747031 |
98 | mRNA splice site selection (GO:0006376) | 2.70389664 |
99 | DNA demethylation (GO:0080111) | 2.70209470 |
100 | DNA synthesis involved in DNA repair (GO:0000731) | 2.69554717 |
101 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.69390253 |
102 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.69390253 |
103 | negative regulation of mitosis (GO:0045839) | 2.67810534 |
104 | histone H3-K9 demethylation (GO:0033169) | 2.66143436 |
105 | DNA replication checkpoint (GO:0000076) | 2.65041755 |
106 | intra-S DNA damage checkpoint (GO:0031573) | 2.65032114 |
107 | RNA destabilization (GO:0050779) | 2.63596994 |
108 | DNA integration (GO:0015074) | 2.61267241 |
109 | histone H3-K9 modification (GO:0061647) | 2.61028616 |
110 | sister chromatid cohesion (GO:0007062) | 2.60980800 |
111 | translesion synthesis (GO:0019985) | 2.60081702 |
112 | epithelial cilium movement (GO:0003351) | 2.59228601 |
113 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.58887066 |
114 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.56340172 |
115 | histone lysine demethylation (GO:0070076) | 2.55874278 |
116 | protein K11-linked ubiquitination (GO:0070979) | 2.55810423 |
117 | microtubule polymerization or depolymerization (GO:0031109) | 2.54913830 |
118 | negative regulation of cell division (GO:0051782) | 2.54249384 |
119 | regulation of meiosis I (GO:0060631) | 2.54206403 |
120 | postreplication repair (GO:0006301) | 2.54152906 |
121 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.53474440 |
122 | positive regulation of B cell differentiation (GO:0045579) | 2.52961965 |
123 | regulation of histone H3-K9 methylation (GO:0051570) | 2.52608917 |
124 | negative regulation of meiotic cell cycle (GO:0051447) | 2.52298323 |
125 | histone demethylation (GO:0016577) | 2.52116874 |
126 | response to interferon-beta (GO:0035456) | 2.51937387 |
127 | viral transcription (GO:0019083) | 2.49265464 |
128 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.48077331 |
129 | spliceosomal snRNP assembly (GO:0000387) | 2.47993030 |
130 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.47488731 |
131 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.47218001 |
132 | establishment of chromosome localization (GO:0051303) | 2.47107456 |
133 | termination of RNA polymerase II transcription (GO:0006369) | 2.47066074 |
134 | reciprocal DNA recombination (GO:0035825) | 2.47048646 |
135 | reciprocal meiotic recombination (GO:0007131) | 2.47048646 |
136 | facial nerve structural organization (GO:0021612) | 2.46872564 |
137 | telomere maintenance via telomere lengthening (GO:0010833) | 2.46379107 |
138 | telomere maintenance (GO:0000723) | 2.45124736 |
139 | ATP-dependent chromatin remodeling (GO:0043044) | 2.44839948 |
140 | telomere organization (GO:0032200) | 2.44684865 |
141 | nuclear pore organization (GO:0006999) | 2.44252598 |
142 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.43595830 |
143 | motile cilium assembly (GO:0044458) | 2.43444838 |
144 | neural tube formation (GO:0001841) | 2.42917786 |
145 | meiotic cell cycle (GO:0051321) | 2.42482577 |
146 | DNA ligation (GO:0006266) | 2.41171194 |
147 | proteasome assembly (GO:0043248) | 2.40286590 |
148 | meiosis I (GO:0007127) | 2.39939091 |
149 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.39923729 |
150 | acrosome reaction (GO:0007340) | 2.39876503 |
151 | single fertilization (GO:0007338) | 2.38667960 |
152 | regulation of cilium movement (GO:0003352) | 2.38307489 |
153 | mitotic sister chromatid cohesion (GO:0007064) | 2.37013168 |
154 | translational termination (GO:0006415) | 2.36536021 |
155 | ribosome biogenesis (GO:0042254) | 2.36350431 |
156 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.36174283 |
157 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.36157992 |
158 | DNA-templated transcription, termination (GO:0006353) | 2.34716735 |
159 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.34521496 |
160 | transcription from RNA polymerase I promoter (GO:0006360) | 2.34121447 |
161 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.33702468 |
162 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.33686929 |
163 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.32584212 |
164 | DNA packaging (GO:0006323) | 2.31528648 |
165 | mismatch repair (GO:0006298) | 2.31403742 |
166 | protein localization to chromosome, centromeric region (GO:0071459) | 2.30290346 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.07796319 |
2 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 4.88560643 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.33431735 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.99022190 |
5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.95648437 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.87371609 |
7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.54724694 |
8 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.35485290 |
9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.34060158 |
10 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.33199570 |
11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.32157978 |
12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.31861590 |
13 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.30673443 |
14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.29433986 |
15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.28299110 |
16 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.26271188 |
17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25223766 |
18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.22930134 |
19 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.15091918 |
20 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.10506225 |
21 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.07738957 |
22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.06588161 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.04317824 |
24 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.02442314 |
25 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.02197208 |
26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.01406450 |
27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00354795 |
28 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.99662413 |
29 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.96025461 |
30 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.93817713 |
31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93143693 |
32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.87836810 |
33 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.84229409 |
34 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.83581612 |
35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.81293851 |
36 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.79566264 |
37 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.75017953 |
38 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.74142563 |
39 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.73677308 |
40 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.72262659 |
41 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.71603435 |
42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.70440885 |
43 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.70193080 |
44 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.70104030 |
45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69936524 |
46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.69121179 |
47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.67418827 |
48 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.61622860 |
49 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.60771728 |
50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.58718257 |
51 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55026862 |
52 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.53579648 |
53 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.53123535 |
54 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52625457 |
55 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.51605735 |
56 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.49276840 |
57 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.48542437 |
58 | FUS_26573619_Chip-Seq_HEK293_Human | 1.46914094 |
59 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.46476662 |
60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.46190508 |
61 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.44783427 |
62 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.43728068 |
63 | MYC_22102868_ChIP-Seq_BL_Human | 1.40297264 |
64 | MYB_26560356_Chip-Seq_TH2_Human | 1.38773241 |
65 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37212771 |
66 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.36991388 |
67 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.36974919 |
68 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.36014633 |
69 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.35900041 |
70 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.35206478 |
71 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.34363470 |
72 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.33732355 |
73 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.33509491 |
74 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.33403323 |
75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32825767 |
76 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.31854417 |
77 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.31331037 |
78 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.30800645 |
79 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.30072607 |
80 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.29156962 |
81 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.29142314 |
82 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.26970666 |
83 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.25556393 |
84 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.25114088 |
85 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23351562 |
86 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22978884 |
87 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.21278074 |
88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.20199522 |
89 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.17964502 |
90 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17864953 |
91 | * MYB_26560356_Chip-Seq_TH1_Human | 1.16777429 |
92 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.16700486 |
93 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.16042966 |
94 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.14185265 |
95 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.12924685 |
96 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.12004381 |
97 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.11977286 |
98 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.11917000 |
99 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.11382369 |
100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.10268250 |
101 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09564059 |
102 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.08141091 |
103 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.07878583 |
104 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.06522361 |
105 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.05080119 |
106 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04091330 |
107 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02030730 |
108 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.00984154 |
109 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.00768485 |
110 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97422075 |
111 | * ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.96741639 |
112 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.95969924 |
113 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.95640689 |
114 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.94377745 |
115 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.94285465 |
116 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.93504842 |
117 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.92030241 |
118 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.91884206 |
119 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91878464 |
120 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.91800557 |
121 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91728021 |
122 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90620940 |
123 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.89218859 |
124 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.88989235 |
125 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85486291 |
126 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.84740198 |
127 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.84513933 |
128 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.84190210 |
129 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.84186297 |
130 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.84117843 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 2.99193278 |
2 | MP0008058_abnormal_DNA_repair | 2.92617222 |
3 | MP0005410_abnormal_fertilization | 2.87169185 |
4 | MP0002102_abnormal_ear_morphology | 2.82929669 |
5 | MP0003693_abnormal_embryo_hatching | 2.80370607 |
6 | MP0006292_abnormal_olfactory_placode | 2.76640835 |
7 | MP0008007_abnormal_cellular_replicative | 2.62123198 |
8 | MP0008877_abnormal_DNA_methylation | 2.52494655 |
9 | MP0008789_abnormal_olfactory_epithelium | 2.46645679 |
10 | MP0005394_taste/olfaction_phenotype | 2.42635308 |
11 | MP0005499_abnormal_olfactory_system | 2.42635308 |
12 | MP0002396_abnormal_hematopoietic_system | 2.28388443 |
13 | MP0003763_abnormal_thymus_physiology | 2.25588650 |
14 | MP0003077_abnormal_cell_cycle | 2.16071546 |
15 | MP0002009_preneoplasia | 2.13048065 |
16 | MP0001929_abnormal_gametogenesis | 2.12663081 |
17 | MP0005671_abnormal_response_to | 2.11279026 |
18 | MP0002210_abnormal_sex_determination | 2.08684250 |
19 | MP0006054_spinal_hemorrhage | 2.07958427 |
20 | MP0004808_abnormal_hematopoietic_stem | 2.02923945 |
21 | MP0003111_abnormal_nucleus_morphology | 2.00241549 |
22 | MP0003724_increased_susceptibility_to | 1.99782909 |
23 | MP0001835_abnormal_antigen_presentation | 1.92772588 |
24 | MP0003787_abnormal_imprinting | 1.87853087 |
25 | MP0003221_abnormal_cardiomyocyte_apopto | 1.84666000 |
26 | MP0004957_abnormal_blastocyst_morpholog | 1.84590364 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.83109735 |
28 | MP0005075_abnormal_melanosome_morpholog | 1.82567459 |
29 | MP0000685_abnormal_immune_system | 1.80471248 |
30 | MP0005174_abnormal_tail_pigmentation | 1.79481932 |
31 | MP0002132_abnormal_respiratory_system | 1.76362881 |
32 | MP0008057_abnormal_DNA_replication | 1.75937313 |
33 | MP0009785_altered_susceptibility_to | 1.75717546 |
34 | MP0003698_abnormal_male_reproductive | 1.69974718 |
35 | MP0001873_stomach_inflammation | 1.69263167 |
36 | MP0000490_abnormal_crypts_of | 1.68741549 |
37 | MP0002398_abnormal_bone_marrow | 1.62587561 |
38 | MP0003786_premature_aging | 1.60776393 |
39 | MP0001145_abnormal_male_reproductive | 1.60282338 |
40 | MP0003880_abnormal_central_pattern | 1.59178552 |
41 | MP0009333_abnormal_splenocyte_physiolog | 1.58124760 |
42 | MP0000566_synostosis | 1.57851954 |
43 | MP0000465_gastrointestinal_hemorrhage | 1.53248027 |
44 | MP0000653_abnormal_sex_gland | 1.51191746 |
45 | MP0002166_altered_tumor_susceptibility | 1.50354031 |
46 | MP0004147_increased_porphyrin_level | 1.49739985 |
47 | MP0001545_abnormal_hematopoietic_system | 1.49584481 |
48 | MP0005397_hematopoietic_system_phenotyp | 1.49584481 |
49 | MP0003943_abnormal_hepatobiliary_system | 1.40817225 |
50 | MP0003136_yellow_coat_color | 1.40773322 |
51 | MP0002095_abnormal_skin_pigmentation | 1.39165204 |
52 | MP0001800_abnormal_humoral_immune | 1.38119733 |
53 | MP0000689_abnormal_spleen_morphology | 1.36278710 |
54 | MP0006035_abnormal_mitochondrial_morpho | 1.35952372 |
55 | MP0001119_abnormal_female_reproductive | 1.34514396 |
56 | MP0002722_abnormal_immune_system | 1.30029781 |
57 | MP0002420_abnormal_adaptive_immunity | 1.29743508 |
58 | MP0002723_abnormal_immune_serum | 1.28618639 |
59 | MP0001819_abnormal_immune_cell | 1.28438772 |
60 | MP0002452_abnormal_antigen_presenting | 1.24278724 |
61 | MP0000716_abnormal_immune_system | 1.23775003 |
62 | MP0003890_abnormal_embryonic-extraembry | 1.22618556 |
63 | MP0006276_abnormal_autonomic_nervous | 1.21820250 |
64 | MP0000703_abnormal_thymus_morphology | 1.19970880 |
65 | MP0008961_abnormal_basal_metabolism | 1.19912323 |
66 | MP0002429_abnormal_blood_cell | 1.19121374 |
67 | MP0005083_abnormal_biliary_tract | 1.18867646 |
68 | MP0001529_abnormal_vocalization | 1.18456193 |
69 | MP0001986_abnormal_taste_sensitivity | 1.17568479 |
70 | MP0006072_abnormal_retinal_apoptosis | 1.17463253 |
71 | MP0000015_abnormal_ear_pigmentation | 1.17454868 |
72 | MP0002019_abnormal_tumor_incidence | 1.15429886 |
73 | MP0005025_abnormal_response_to | 1.14324477 |
74 | MP0001919_abnormal_reproductive_system | 1.13973037 |
75 | MP0009697_abnormal_copulation | 1.13765285 |
76 | MP0001730_embryonic_growth_arrest | 1.12449673 |
77 | MP0005389_reproductive_system_phenotype | 1.08603741 |
78 | MP0000358_abnormal_cell_content/ | 1.08035478 |
79 | MP0003718_maternal_effect | 1.07552772 |
80 | MP0004381_abnormal_hair_follicle | 1.07129350 |
81 | MP0005000_abnormal_immune_tolerance | 1.07078419 |
82 | MP0002006_tumorigenesis | 1.06480806 |
83 | MP0000569_abnormal_digit_pigmentation | 1.03695812 |
84 | MP0001293_anophthalmia | 1.02964398 |
85 | MP0001286_abnormal_eye_development | 1.02940370 |
86 | MP0009840_abnormal_foam_cell | 1.02899311 |
87 | MP0002160_abnormal_reproductive_system | 1.01426575 |
88 | MP0005464_abnormal_platelet_physiology | 1.01420498 |
89 | MP0002148_abnormal_hypersensitivity_rea | 1.00706435 |
90 | MP0000313_abnormal_cell_death | 0.98961501 |
91 | MP0002163_abnormal_gland_morphology | 0.97666754 |
92 | MP0000350_abnormal_cell_proliferation | 0.97633552 |
93 | MP0002161_abnormal_fertility/fecundity | 0.97023272 |
94 | MP0005257_abnormal_intraocular_pressure | 0.96611783 |
95 | MP0003878_abnormal_ear_physiology | 0.96560976 |
96 | MP0005377_hearing/vestibular/ear_phenot | 0.96560976 |
97 | MP0003436_decreased_susceptibility_to | 0.94408950 |
98 | MP0008995_early_reproductive_senescence | 0.93500669 |
99 | MP0003121_genomic_imprinting | 0.92427248 |
100 | MP0008932_abnormal_embryonic_tissue | 0.92083946 |
101 | MP0010155_abnormal_intestine_physiology | 0.91770128 |
102 | MP0010368_abnormal_lymphatic_system | 0.90934284 |
103 | MP0001188_hyperpigmentation | 0.90176134 |
104 | MP0001853_heart_inflammation | 0.89927180 |
105 | MP0005670_abnormal_white_adipose | 0.89394761 |
106 | MP0002405_respiratory_system_inflammati | 0.87830763 |
107 | MP0004782_abnormal_surfactant_physiolog | 0.86391531 |
108 | MP0010307_abnormal_tumor_latency | 0.86119661 |
109 | MP0003011_delayed_dark_adaptation | 0.85954238 |
110 | MP0005187_abnormal_penis_morphology | 0.85624527 |
111 | MP0001697_abnormal_embryo_size | 0.85608588 |
112 | MP0002419_abnormal_innate_immunity | 0.84436444 |
113 | MP0001764_abnormal_homeostasis | 0.83300548 |
114 | MP0006036_abnormal_mitochondrial_physio | 0.82777305 |
115 | MP0008260_abnormal_autophagy | 0.81684686 |
116 | MP0000631_abnormal_neuroendocrine_gland | 0.80050841 |
117 | MP0005367_renal/urinary_system_phenotyp | 0.79777729 |
118 | MP0000516_abnormal_urinary_system | 0.79777729 |
119 | MP0000372_irregular_coat_pigmentation | 0.79315965 |
120 | MP0002249_abnormal_larynx_morphology | 0.78691763 |
121 | MP0003828_pulmonary_edema | 0.78073561 |
122 | MP0000681_abnormal_thyroid_gland | 0.77622453 |
123 | MP0004142_abnormal_muscle_tone | 0.77538816 |
124 | MP0000049_abnormal_middle_ear | 0.76696327 |
125 | MP0003315_abnormal_perineum_morphology | 0.75086318 |
126 | MP0001845_abnormal_inflammatory_respons | 0.74160734 |
127 | MP0005084_abnormal_gallbladder_morpholo | 0.73571562 |
128 | MP0008004_abnormal_stomach_pH | 0.73187157 |
129 | MP0003699_abnormal_female_reproductive | 0.72653461 |
130 | MP0005408_hypopigmentation | 0.72545407 |
131 | MP0004197_abnormal_fetal_growth/weight/ | 0.72345829 |
132 | MP0005380_embryogenesis_phenotype | 0.72149604 |
133 | MP0001672_abnormal_embryogenesis/_devel | 0.72149604 |
134 | MP0005384_cellular_phenotype | 0.71579082 |
135 | MP0009765_abnormal_xenobiotic_induced | 0.71553902 |
136 | MP0005647_abnormal_sex_gland | 0.71271402 |
137 | MP0002233_abnormal_nose_morphology | 0.71244458 |
138 | MP0005387_immune_system_phenotype | 0.71234168 |
139 | MP0001790_abnormal_immune_system | 0.71234168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.21329128 |
2 | Amyotrophic lateral sclerosis (HP:0007354) | 3.93228421 |
3 | Prostate neoplasm (HP:0100787) | 3.70015026 |
4 | Shoulder girdle muscle weakness (HP:0003547) | 3.61704520 |
5 | Abnormal number of erythroid precursors (HP:0012131) | 3.57746427 |
6 | Volvulus (HP:0002580) | 3.55020333 |
7 | Abnormal spermatogenesis (HP:0008669) | 3.49546542 |
8 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.44076135 |
9 | Absent/shortened dynein arms (HP:0200106) | 3.42592362 |
10 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.42592362 |
11 | Cortical dysplasia (HP:0002539) | 3.42332710 |
12 | Abnormality of the labia minora (HP:0012880) | 3.25146041 |
13 | Type 2 muscle fiber atrophy (HP:0003554) | 3.18216278 |
14 | Rimmed vacuoles (HP:0003805) | 3.08723331 |
15 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 3.07920450 |
16 | Abnormality of the prostate (HP:0008775) | 2.99039292 |
17 | Muscle fiber atrophy (HP:0100295) | 2.98306497 |
18 | Aplastic anemia (HP:0001915) | 2.98292995 |
19 | Birth length less than 3rd percentile (HP:0003561) | 2.92044185 |
20 | Azoospermia (HP:0000027) | 2.89646908 |
21 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.77882788 |
22 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.77882788 |
23 | Recurrent bronchitis (HP:0002837) | 2.76496337 |
24 | Supernumerary spleens (HP:0009799) | 2.72547901 |
25 | Abnormality of the lower motor neuron (HP:0002366) | 2.64510362 |
26 | Bronchitis (HP:0012387) | 2.63583980 |
27 | Abnormality of chromosome stability (HP:0003220) | 2.61689057 |
28 | Abnormality of the corticospinal tract (HP:0002492) | 2.56415246 |
29 | Microvesicular hepatic steatosis (HP:0001414) | 2.56216972 |
30 | Chromsome breakage (HP:0040012) | 2.53831076 |
31 | Nephrogenic diabetes insipidus (HP:0009806) | 2.53801214 |
32 | Medulloblastoma (HP:0002885) | 2.53203832 |
33 | Thrombocytosis (HP:0001894) | 2.52117859 |
34 | Congenital primary aphakia (HP:0007707) | 2.49571968 |
35 | Reduced antithrombin III activity (HP:0001976) | 2.47781914 |
36 | Meckel diverticulum (HP:0002245) | 2.46703994 |
37 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.46552213 |
38 | Myelodysplasia (HP:0002863) | 2.45747913 |
39 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.44907783 |
40 | Chronic bronchitis (HP:0004469) | 2.44215444 |
41 | Type I transferrin isoform profile (HP:0003642) | 2.43362467 |
42 | Pelvic girdle muscle weakness (HP:0003749) | 2.40147156 |
43 | True hermaphroditism (HP:0010459) | 2.39655468 |
44 | 11 pairs of ribs (HP:0000878) | 2.37123721 |
45 | Basal cell carcinoma (HP:0002671) | 2.36972347 |
46 | Tubulointerstitial nephritis (HP:0001970) | 2.36074514 |
47 | Carpal bone hypoplasia (HP:0001498) | 2.35380125 |
48 | Poikilocytosis (HP:0004447) | 2.35133966 |
49 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.33989701 |
50 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.33989701 |
51 | IgM deficiency (HP:0002850) | 2.33071654 |
52 | Petechiae (HP:0000967) | 2.33058717 |
53 | Severe visual impairment (HP:0001141) | 2.32798304 |
54 | Reticulocytopenia (HP:0001896) | 2.32668604 |
55 | Abnormality of the ileum (HP:0001549) | 2.30530013 |
56 | Selective tooth agenesis (HP:0001592) | 2.29987788 |
57 | Myositis (HP:0100614) | 2.29095233 |
58 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.28299380 |
59 | Prolonged bleeding time (HP:0003010) | 2.27393255 |
60 | Nasal polyposis (HP:0100582) | 2.26426555 |
61 | Abnormality of T cell physiology (HP:0011840) | 2.26217680 |
62 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.25133065 |
63 | Spinal cord lesions (HP:0100561) | 2.24809547 |
64 | Syringomyelia (HP:0003396) | 2.24809547 |
65 | Abnormality of the preputium (HP:0100587) | 2.24774903 |
66 | Recurrent sinusitis (HP:0011108) | 2.23896171 |
67 | Pancreatic fibrosis (HP:0100732) | 2.22720812 |
68 | Nonprogressive disorder (HP:0003680) | 2.22485833 |
69 | Gait imbalance (HP:0002141) | 2.22328765 |
70 | Papillary thyroid carcinoma (HP:0002895) | 2.21447921 |
71 | Chronic hepatic failure (HP:0100626) | 2.21039837 |
72 | Gonadotropin excess (HP:0000837) | 2.19976332 |
73 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.19510691 |
74 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.19510691 |
75 | Abnormal protein glycosylation (HP:0012346) | 2.18088445 |
76 | Abnormal glycosylation (HP:0012345) | 2.18088445 |
77 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.18088445 |
78 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.18088445 |
79 | Rhinitis (HP:0012384) | 2.17959923 |
80 | Abnormal lung lobation (HP:0002101) | 2.17386424 |
81 | Clubbing of toes (HP:0100760) | 2.16807777 |
82 | Facial hemangioma (HP:0000329) | 2.16197131 |
83 | Dyskinesia (HP:0100660) | 2.13596224 |
84 | Bronchiectasis (HP:0002110) | 2.13305331 |
85 | Pancreatic cysts (HP:0001737) | 2.13042183 |
86 | Nephronophthisis (HP:0000090) | 2.10115198 |
87 | Thyroid carcinoma (HP:0002890) | 2.09582511 |
88 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.09316449 |
89 | Abnormality of male internal genitalia (HP:0000022) | 2.08714438 |
90 | Abnormality of B cell number (HP:0010975) | 2.07466977 |
91 | B lymphocytopenia (HP:0010976) | 2.07466977 |
92 | T lymphocytopenia (HP:0005403) | 2.06544531 |
93 | Stomach cancer (HP:0012126) | 2.06452232 |
94 | Attenuation of retinal blood vessels (HP:0007843) | 2.03733596 |
95 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.03355658 |
96 | Abnormality of alanine metabolism (HP:0010916) | 2.03271832 |
97 | Hyperalaninemia (HP:0003348) | 2.03271832 |
98 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.03271832 |
99 | Optic neuritis (HP:0100653) | 2.02601804 |
100 | Retrobulbar optic neuritis (HP:0100654) | 2.02601804 |
101 | Long clavicles (HP:0000890) | 2.00200019 |
102 | Abnormality of T cell number (HP:0011839) | 1.99492839 |
103 | Combined immunodeficiency (HP:0005387) | 1.98633670 |
104 | Abnormality of T cells (HP:0002843) | 1.96558049 |
105 | Small intestinal stenosis (HP:0012848) | 1.95787708 |
106 | Duodenal stenosis (HP:0100867) | 1.95787708 |
107 | Dyschromatopsia (HP:0007641) | 1.94870517 |
108 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.93383457 |
109 | Abnormality of the nasal mucosa (HP:0000433) | 1.93287234 |
110 | Oligodactyly (hands) (HP:0001180) | 1.92963407 |
111 | Premature ovarian failure (HP:0008209) | 1.92836578 |
112 | Hypoplastic iliac wings (HP:0002866) | 1.92732939 |
113 | Acute myeloid leukemia (HP:0004808) | 1.91314459 |
114 | Abnormal biliary tract physiology (HP:0012439) | 1.91159212 |
115 | Bile duct proliferation (HP:0001408) | 1.91159212 |
116 | Abnormality of the anterior horn cell (HP:0006802) | 1.91105996 |
117 | Degeneration of anterior horn cells (HP:0002398) | 1.91105996 |
118 | Sloping forehead (HP:0000340) | 1.89777016 |
119 | Abnormality of midbrain morphology (HP:0002418) | 1.89758329 |
120 | Molar tooth sign on MRI (HP:0002419) | 1.89758329 |
121 | Abnormal ciliary motility (HP:0012262) | 1.87944413 |
122 | Colon cancer (HP:0003003) | 1.85808327 |
123 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.85375756 |
124 | Amaurosis fugax (HP:0100576) | 1.85121418 |
125 | Absent thumb (HP:0009777) | 1.84906886 |
126 | Stomatitis (HP:0010280) | 1.84615547 |
127 | Severe combined immunodeficiency (HP:0004430) | 1.83648281 |
128 | Medial flaring of the eyebrow (HP:0010747) | 1.81077762 |
129 | Congenital, generalized hypertrichosis (HP:0004540) | 1.80908979 |
130 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.80789206 |
131 | Abnormality of eosinophils (HP:0001879) | 1.80699295 |
132 | Microretrognathia (HP:0000308) | 1.79465036 |
133 | Patellar aplasia (HP:0006443) | 1.79398754 |
134 | Abnormality of lateral ventricle (HP:0030047) | 1.79363389 |
135 | Embryonal renal neoplasm (HP:0011794) | 1.79316827 |
136 | Capillary hemangiomas (HP:0005306) | 1.78906828 |
137 | Lymphoma (HP:0002665) | 1.78058615 |
138 | Impulsivity (HP:0100710) | 1.77059602 |
139 | Abnormality of the duodenum (HP:0002246) | 1.76627067 |
140 | Panhypogammaglobulinemia (HP:0003139) | 1.76209625 |
141 | Pallor (HP:0000980) | 1.75738966 |
142 | Sparse eyelashes (HP:0000653) | 1.74738422 |
143 | Abnormality of the renal medulla (HP:0100957) | 1.74484099 |
144 | Abnormality of the fingertips (HP:0001211) | 1.74327590 |
145 | Thyroiditis (HP:0100646) | 1.73718885 |
146 | Median cleft lip (HP:0000161) | 1.73391798 |
147 | Chronic otitis media (HP:0000389) | 1.73296754 |
148 | Intestinal atresia (HP:0011100) | 1.73176333 |
149 | Lissencephaly (HP:0001339) | 1.73081626 |
150 | Cerebellar dysplasia (HP:0007033) | 1.71630053 |
151 | Acute hepatic failure (HP:0006554) | 1.67505189 |
152 | Retinal dysplasia (HP:0007973) | 1.66678463 |
153 | Vaginal atresia (HP:0000148) | 1.66373848 |
154 | Male infertility (HP:0003251) | 1.66298894 |
155 | Paralysis (HP:0003470) | 1.66153759 |
156 | Acanthocytosis (HP:0001927) | 1.65890400 |
157 | Cystic hygroma (HP:0000476) | 1.65726289 |
158 | Biliary tract neoplasm (HP:0100574) | 1.65567422 |
159 | Reticulocytosis (HP:0001923) | 1.64835246 |
160 | Genital tract atresia (HP:0001827) | 1.64557095 |
161 | Stenosis of the external auditory canal (HP:0000402) | 1.64069644 |
162 | Poor coordination (HP:0002370) | 1.63452419 |
163 | Specific learning disability (HP:0001328) | 1.63208049 |
164 | Increased IgM level (HP:0003496) | 1.63071962 |
165 | Abnormality of the pons (HP:0007361) | 1.62937723 |
166 | Limb hypertonia (HP:0002509) | 1.61281633 |
167 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.61054605 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28 | 3.88467709 |
2 | ACVR1B | 3.81219139 |
3 | MUSK | 3.23641909 |
4 | CDK19 | 3.19295075 |
5 | BRD4 | 3.18176361 |
6 | SRPK1 | 3.17829898 |
7 | PIM2 | 2.78580696 |
8 | MST1R | 2.73350582 |
9 | STK16 | 2.65719188 |
10 | MKNK1 | 2.56097766 |
11 | MKNK2 | 2.52814887 |
12 | MAP3K4 | 2.47870870 |
13 | WEE1 | 2.47624028 |
14 | DYRK3 | 2.16692955 |
15 | NLK | 2.08668639 |
16 | CDC7 | 2.07499612 |
17 | BCR | 2.05081441 |
18 | BUB1 | 2.02194832 |
19 | IRAK4 | 1.94257647 |
20 | TXK | 1.80112603 |
21 | PIK3CA | 1.73611110 |
22 | VRK1 | 1.69893283 |
23 | TEC | 1.63616411 |
24 | TGFBR1 | 1.62971618 |
25 | PLK4 | 1.55811983 |
26 | NME2 | 1.53169488 |
27 | TESK2 | 1.52365824 |
28 | BRSK2 | 1.47328241 |
29 | NEK2 | 1.47318868 |
30 | RPS6KA4 | 1.42874007 |
31 | KIT | 1.42815349 |
32 | EEF2K | 1.42440773 |
33 | BTK | 1.38687776 |
34 | TNIK | 1.38405011 |
35 | CDK12 | 1.37587731 |
36 | IKBKE | 1.36185190 |
37 | PRPF4B | 1.36142768 |
38 | IRAK1 | 1.33661229 |
39 | MAP4K1 | 1.33105890 |
40 | SIK3 | 1.31087665 |
41 | MAP3K5 | 1.29073691 |
42 | RAF1 | 1.25407225 |
43 | MAPKAPK3 | 1.22546729 |
44 | TLK1 | 1.21450089 |
45 | PIM1 | 1.21129204 |
46 | FLT3 | 1.20327038 |
47 | ATR | 1.15457518 |
48 | CDK8 | 1.15450175 |
49 | CCNB1 | 1.15392022 |
50 | CDK3 | 1.14551670 |
51 | TGFBR2 | 1.10773973 |
52 | CDK9 | 1.08585268 |
53 | CHEK2 | 1.08053958 |
54 | CDK4 | 1.06474635 |
55 | PDK4 | 1.05572621 |
56 | PDK3 | 1.05572621 |
57 | TBK1 | 1.05505051 |
58 | EPHA3 | 1.04704670 |
59 | PASK | 1.04444291 |
60 | MAP3K14 | 1.02973173 |
61 | ZAK | 1.01362372 |
62 | IRAK2 | 0.99568726 |
63 | YES1 | 0.98774444 |
64 | JAK3 | 0.97818311 |
65 | ZAP70 | 0.97622694 |
66 | EIF2AK3 | 0.97478739 |
67 | TSSK6 | 0.96812333 |
68 | MAP2K2 | 0.96103791 |
69 | AURKB | 0.93949051 |
70 | MAPK13 | 0.93427828 |
71 | PLK1 | 0.92879301 |
72 | EIF2AK2 | 0.90888598 |
73 | BMPR1B | 0.90141746 |
74 | CDK7 | 0.90080823 |
75 | KDR | 0.89693669 |
76 | EIF2AK1 | 0.87870498 |
77 | RPS6KB2 | 0.87338765 |
78 | ERBB3 | 0.85807960 |
79 | TAOK1 | 0.80235272 |
80 | CHUK | 0.78155639 |
81 | WNK3 | 0.77722660 |
82 | IRAK3 | 0.75743188 |
83 | IKBKB | 0.75742555 |
84 | TTK | 0.75526300 |
85 | MAP4K2 | 0.74184559 |
86 | STK10 | 0.73704879 |
87 | DYRK1A | 0.73564092 |
88 | PNCK | 0.71243117 |
89 | AKT3 | 0.70767043 |
90 | TIE1 | 0.69573442 |
91 | CLK1 | 0.69055240 |
92 | SYK | 0.68905830 |
93 | OXSR1 | 0.66482710 |
94 | NEK6 | 0.66397137 |
95 | RPS6KA5 | 0.66026343 |
96 | MAP3K2 | 0.65397252 |
97 | PLK3 | 0.65367198 |
98 | MAPKAPK5 | 0.64698668 |
99 | UHMK1 | 0.62941692 |
100 | TYK2 | 0.62408947 |
101 | GRK1 | 0.61254949 |
102 | FGR | 0.61047443 |
103 | BRSK1 | 0.59793043 |
104 | DYRK1B | 0.59389737 |
105 | NUAK1 | 0.58536033 |
106 | TAOK2 | 0.57697599 |
107 | CDK6 | 0.57217732 |
108 | LYN | 0.56036089 |
109 | MST4 | 0.55749135 |
110 | DYRK2 | 0.55654049 |
111 | TAOK3 | 0.55477149 |
112 | CSNK2A1 | 0.55072531 |
113 | PDK2 | 0.54709685 |
114 | ATM | 0.54033935 |
115 | SIK2 | 0.53714881 |
116 | CASK | 0.52738663 |
117 | CAMKK2 | 0.52352870 |
118 | MARK3 | 0.52202625 |
119 | CDK2 | 0.52193934 |
120 | MAP3K10 | 0.52131690 |
121 | PRKG2 | 0.51960551 |
122 | MAPK15 | 0.51093491 |
123 | STK4 | 0.49966460 |
124 | JAK2 | 0.49167752 |
125 | MAP2K4 | 0.48192812 |
126 | HCK | 0.48018642 |
127 | GRK7 | 0.47306686 |
128 | RPS6KA1 | 0.44931231 |
129 | MAP2K7 | 0.44912801 |
130 | CSF1R | 0.44072089 |
131 | MAP2K3 | 0.42889557 |
132 | BRAF | 0.42445811 |
133 | LCK | 0.42032522 |
134 | MAPK9 | 0.41871819 |
135 | TESK1 | 0.41779074 |
136 | STK38L | 0.41651579 |
137 | CHEK1 | 0.41345342 |
138 | MAP3K11 | 0.40821531 |
139 | ADRBK2 | 0.40120413 |
140 | AURKA | 0.39885939 |
141 | PIK3CG | 0.39716904 |
142 | PRKCQ | 0.38090421 |
143 | MATK | 0.37756075 |
144 | CSNK1G2 | 0.35025199 |
145 | PLK2 | 0.33397937 |
146 | CDK1 | 0.32252771 |
147 | EPHA4 | 0.30672017 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.84126251 |
2 | Base excision repair_Homo sapiens_hsa03410 | 3.07618260 |
3 | Spliceosome_Homo sapiens_hsa03040 | 3.02512132 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 2.91586051 |
5 | Homologous recombination_Homo sapiens_hsa03440 | 2.86344660 |
6 | Basal transcription factors_Homo sapiens_hsa03022 | 2.71382532 |
7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.60958730 |
8 | Ribosome_Homo sapiens_hsa03010 | 2.58607161 |
9 | RNA polymerase_Homo sapiens_hsa03020 | 2.55657722 |
10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.46393925 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.33051758 |
12 | RNA transport_Homo sapiens_hsa03013 | 2.23760451 |
13 | Cell cycle_Homo sapiens_hsa04110 | 2.21504356 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.17682473 |
15 | RNA degradation_Homo sapiens_hsa03018 | 2.02265226 |
16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89547082 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.88238513 |
18 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.85550502 |
19 | Proteasome_Homo sapiens_hsa03050 | 1.77468415 |
20 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.70781096 |
21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.65203461 |
22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.61051137 |
23 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.60959082 |
24 | Purine metabolism_Homo sapiens_hsa00230 | 1.44495070 |
25 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.44132348 |
26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.41368170 |
27 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.36311368 |
28 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.32591713 |
29 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.30584461 |
30 | Protein export_Homo sapiens_hsa03060 | 1.27868723 |
31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.27867621 |
32 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.26755395 |
33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.26500825 |
34 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.22650817 |
35 | Measles_Homo sapiens_hsa05162 | 1.21807927 |
36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.20239086 |
37 | Circadian rhythm_Homo sapiens_hsa04710 | 1.20196220 |
38 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.19431914 |
39 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.12553720 |
40 | Thyroid cancer_Homo sapiens_hsa05216 | 1.08939563 |
41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.08610303 |
42 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.05025943 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00712494 |
44 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.00345074 |
45 | Legionellosis_Homo sapiens_hsa05134 | 0.98665431 |
46 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97875244 |
47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.95494120 |
48 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.93808664 |
49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.93616348 |
50 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.91208622 |
51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90674081 |
52 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.90027169 |
53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.89046186 |
54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.87996528 |
55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.86087242 |
56 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.82572079 |
57 | Influenza A_Homo sapiens_hsa05164 | 0.80468586 |
58 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.77932759 |
59 | Leishmaniasis_Homo sapiens_hsa05140 | 0.76692474 |
60 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.76443788 |
61 | Allograft rejection_Homo sapiens_hsa05330 | 0.75774128 |
62 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.74079274 |
63 | Hepatitis B_Homo sapiens_hsa05161 | 0.73090905 |
64 | HTLV-I infection_Homo sapiens_hsa05166 | 0.72782594 |
65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72449661 |
66 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.69514745 |
67 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.66902438 |
68 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.65910228 |
69 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.64982181 |
70 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.64213580 |
71 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.63964233 |
72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.62835367 |
73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62188077 |
74 | Salmonella infection_Homo sapiens_hsa05132 | 0.61909661 |
75 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.61240920 |
76 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.57556372 |
77 | Phototransduction_Homo sapiens_hsa04744 | 0.57025881 |
78 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.56943587 |
79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56474329 |
80 | Shigellosis_Homo sapiens_hsa05131 | 0.56347787 |
81 | Apoptosis_Homo sapiens_hsa04210 | 0.54570561 |
82 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.53154860 |
83 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.52769230 |
84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52657765 |
85 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.51672449 |
86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.51450488 |
87 | ABC transporters_Homo sapiens_hsa02010 | 0.51341919 |
88 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.50948002 |
89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.49196005 |
90 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.47379899 |
91 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.45741042 |
92 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44836177 |
93 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.44253284 |
94 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.42741890 |
95 | Platelet activation_Homo sapiens_hsa04611 | 0.42577255 |
96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41477314 |
97 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.41342072 |
98 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.41169978 |
99 | Phagosome_Homo sapiens_hsa04145 | 0.41084042 |
100 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40773625 |
101 | Other glycan degradation_Homo sapiens_hsa00511 | 0.40755227 |
102 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.40665131 |
103 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40325761 |
104 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40107282 |
105 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.39892328 |
106 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.39555645 |
107 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.39199581 |
108 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.38756153 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.38199498 |
110 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.38122526 |
111 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36521455 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.35057817 |
113 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.34673884 |
114 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.34008306 |
115 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.33927869 |
116 | Colorectal cancer_Homo sapiens_hsa05210 | 0.33755675 |
117 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33623284 |
118 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.33080182 |
119 | Prostate cancer_Homo sapiens_hsa05215 | 0.31709707 |
120 | Malaria_Homo sapiens_hsa05144 | 0.30640484 |
121 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.30249231 |
122 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.29807773 |
123 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.29107582 |
124 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.28769927 |
125 | Pertussis_Homo sapiens_hsa05133 | 0.28243224 |
126 | Asthma_Homo sapiens_hsa05310 | 0.27744313 |
127 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.27362083 |
128 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.25832899 |
129 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.25820135 |
130 | Viral myocarditis_Homo sapiens_hsa05416 | 0.24720629 |
131 | Hepatitis C_Homo sapiens_hsa05160 | 0.24534741 |
132 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.23727989 |
133 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.23255857 |
134 | Endometrial cancer_Homo sapiens_hsa05213 | 0.21605729 |