CDS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.17414399
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.04028146
3locomotory exploration behavior (GO:0035641)5.80953300
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.54033131
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.06961242
6glutamate secretion (GO:0014047)5.02787521
7synaptic vesicle exocytosis (GO:0016079)4.85278924
8regulation of synaptic vesicle exocytosis (GO:2000300)4.80594488
9vocalization behavior (GO:0071625)4.75840033
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.58586198
11sodium ion export (GO:0071436)4.48452296
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.44922077
13cellular potassium ion homeostasis (GO:0030007)4.43345397
14neurotransmitter secretion (GO:0007269)4.40291091
15regulation of glutamate receptor signaling pathway (GO:1900449)4.34583095
16gamma-aminobutyric acid transport (GO:0015812)4.30328360
17proline transport (GO:0015824)4.29773910
18regulation of synaptic vesicle transport (GO:1902803)4.28408349
19layer formation in cerebral cortex (GO:0021819)4.24206120
20exploration behavior (GO:0035640)4.14427994
21neuronal action potential propagation (GO:0019227)4.09399530
22regulation of neuronal synaptic plasticity (GO:0048168)4.07227550
23regulation of synapse structural plasticity (GO:0051823)4.06468750
24ionotropic glutamate receptor signaling pathway (GO:0035235)4.04684129
25cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.97461224
26regulation of long-term neuronal synaptic plasticity (GO:0048169)3.97397264
27presynaptic membrane organization (GO:0097090)3.93494825
28activation of protein kinase A activity (GO:0034199)3.92437809
29protein localization to synapse (GO:0035418)3.87684016
30presynaptic membrane assembly (GO:0097105)3.80937679
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.79261365
32detection of calcium ion (GO:0005513)3.74120150
33glycine transport (GO:0015816)3.65104287
34cell communication by electrical coupling (GO:0010644)3.65102049
35positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.62451123
36long-term memory (GO:0007616)3.61713555
37neuromuscular process controlling posture (GO:0050884)3.61219559
38synaptic transmission, glutamatergic (GO:0035249)3.59880372
39neuromuscular process controlling balance (GO:0050885)3.58542396
40negative regulation of cytosolic calcium ion concentration (GO:0051481)3.57790341
41regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.55590395
42neurotransmitter transport (GO:0006836)3.55344271
43dendritic spine morphogenesis (GO:0060997)3.53600779
44cerebellar Purkinje cell differentiation (GO:0021702)3.51854405
45regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.51779501
46negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.49772929
47glutamate receptor signaling pathway (GO:0007215)3.46180035
48neurotransmitter-gated ion channel clustering (GO:0072578)3.45353294
49potassium ion import (GO:0010107)3.44281358
50neuron cell-cell adhesion (GO:0007158)3.43501194
51positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.41546866
52regulation of ARF protein signal transduction (GO:0032012)3.40988214
53postsynaptic membrane organization (GO:0001941)3.40611501
54neuron-neuron synaptic transmission (GO:0007270)3.38220213
55membrane depolarization during action potential (GO:0086010)3.37013567
56positive regulation of synaptic transmission, GABAergic (GO:0032230)3.34391407
57regulation of excitatory postsynaptic membrane potential (GO:0060079)3.34082984
58regulation of neurotransmitter levels (GO:0001505)3.30402949
59positive regulation of membrane potential (GO:0045838)3.28002666
60vesicle transport along microtubule (GO:0047496)3.24027471
61prepulse inhibition (GO:0060134)3.20091747
62regulation of postsynaptic membrane potential (GO:0060078)3.19684775
63regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.19535266
64regulation of synaptic plasticity (GO:0048167)3.17189144
65synaptic vesicle endocytosis (GO:0048488)3.15114959
66cellular sodium ion homeostasis (GO:0006883)3.14681970
67positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.11429239
68alanine transport (GO:0032328)3.11062064
69dendrite morphogenesis (GO:0048813)3.09272705
70regulation of neurotransmitter secretion (GO:0046928)3.07792465
71potassium ion homeostasis (GO:0055075)3.07345245
72transmission of nerve impulse (GO:0019226)3.04902986
73regulation of clathrin-mediated endocytosis (GO:2000369)3.04230003
74positive regulation of synapse maturation (GO:0090129)3.03981446
75regulation of dendritic spine morphogenesis (GO:0061001)3.02897406
76positive regulation of neurotransmitter transport (GO:0051590)3.00327225
77cell communication involved in cardiac conduction (GO:0086065)3.00069498
78positive regulation of potassium ion transmembrane transport (GO:1901381)2.99955230
79response to auditory stimulus (GO:0010996)2.99512843
80mating behavior (GO:0007617)2.98046855
81axonal fasciculation (GO:0007413)2.97532206
82negative regulation of dendrite morphogenesis (GO:0050774)2.96870068
83pyrimidine nucleobase catabolic process (GO:0006208)2.95761718
84negative regulation of dendrite development (GO:2000171)2.95267500
85membrane depolarization (GO:0051899)2.94572375
86regulation of synaptic transmission, glutamatergic (GO:0051966)2.93615786
87auditory behavior (GO:0031223)2.91951871
88L-amino acid import (GO:0043092)2.90427334
89dendritic spine organization (GO:0097061)2.90426643
90neuronal ion channel clustering (GO:0045161)2.86696080
91membrane hyperpolarization (GO:0060081)2.86259220
92neuromuscular process (GO:0050905)2.86115315
93regulation of neurotransmitter transport (GO:0051588)2.85153653
94regulation of vesicle fusion (GO:0031338)2.84323747
95establishment of nucleus localization (GO:0040023)2.84240706
96organelle transport along microtubule (GO:0072384)2.83983599
97membrane repolarization (GO:0086009)2.83959963
98long-term synaptic potentiation (GO:0060291)2.82762453
99neuron recognition (GO:0008038)2.81828530
100positive regulation of neurotransmitter secretion (GO:0001956)2.81761420
101negative regulation of neurotransmitter transport (GO:0051589)2.80475360
102innervation (GO:0060384)2.80368571
103glycerophospholipid catabolic process (GO:0046475)2.79321475
104axon cargo transport (GO:0008088)2.78364279
105G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.77872517
106inositol phosphate catabolic process (GO:0071545)2.76877709
107cerebellar Purkinje cell layer development (GO:0021680)2.76682026
108gamma-aminobutyric acid signaling pathway (GO:0007214)2.76230633
109social behavior (GO:0035176)2.72776394
110intraspecies interaction between organisms (GO:0051703)2.72776394
111chemosensory behavior (GO:0007635)2.72315531
112positive regulation of synaptic transmission (GO:0050806)2.71824603
113cytoskeletal anchoring at plasma membrane (GO:0007016)2.70944562
114negative regulation of synaptic transmission, GABAergic (GO:0032229)2.69772821
115adult walking behavior (GO:0007628)2.69357886
116regulation of synaptic transmission (GO:0050804)2.68866487
117regulation of beta-amyloid formation (GO:1902003)2.67339758
118neurotransmitter uptake (GO:0001504)2.64719369
119catecholamine transport (GO:0051937)2.63523933
120positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.63442091
121nucleobase catabolic process (GO:0046113)2.63052879
122cerebellar granule cell differentiation (GO:0021707)2.61217031
123inositol phosphate dephosphorylation (GO:0046855)2.58618158
124phosphorylated carbohydrate dephosphorylation (GO:0046838)2.58618158
125axon ensheathment in central nervous system (GO:0032291)2.57969766
126central nervous system myelination (GO:0022010)2.57969766
127synapse assembly (GO:0007416)2.57727618
128regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.54014741
129regulation of calcium ion-dependent exocytosis (GO:0017158)2.52574533
130regulation of neurotransmitter uptake (GO:0051580)2.52369867
131dopamine transport (GO:0015872)2.50555224
132brain morphogenesis (GO:0048854)2.47384530
133insulin secretion (GO:0030073)2.46133178
134regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.45754231
135regulation of exocytosis (GO:0017157)2.41888299

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.10917710
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.82535105
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.79477628
4DROSHA_22980978_ChIP-Seq_HELA_Human2.78807284
5RARB_27405468_Chip-Seq_BRAIN_Mouse2.72168766
6REST_21632747_ChIP-Seq_MESCs_Mouse2.63168235
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.57887121
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.51582602
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.51582602
10GBX2_23144817_ChIP-Seq_PC3_Human2.51429253
11MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44349173
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42444510
13EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.40178939
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.36084126
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.27705359
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.26636693
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.24418076
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.21283587
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.17878848
20IKZF1_21737484_ChIP-ChIP_HCT116_Human2.12529420
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04448601
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.03535942
23ZFP57_27257070_Chip-Seq_ESCs_Mouse2.01884216
24EZH2_27304074_Chip-Seq_ESCs_Mouse1.95413578
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94764912
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.93322364
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.83721672
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.82978176
29ERG_21242973_ChIP-ChIP_JURKAT_Human1.81732266
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.73922306
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.72745603
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.72031274
33CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.69228092
34IGF1R_20145208_ChIP-Seq_DFB_Human1.65858420
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.65018892
36P300_19829295_ChIP-Seq_ESCs_Human1.60533998
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57201638
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.56977516
39KDM2B_26808549_Chip-Seq_K562_Human1.56472194
40* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.55597800
41AR_21572438_ChIP-Seq_LNCaP_Human1.53733557
42DNAJC2_21179169_ChIP-ChIP_NT2_Human1.52244274
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51761980
44TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.49618982
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44786044
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.44786044
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42271913
48EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.41648161
49SMAD4_21799915_ChIP-Seq_A2780_Human1.39833483
50* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39094507
51* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38497705
52* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.38427931
53* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.36071453
54NR3C1_23031785_ChIP-Seq_PC12_Mouse1.33217475
55RNF2_27304074_Chip-Seq_NSC_Mouse1.32252808
56WT1_25993318_ChIP-Seq_PODOCYTE_Human1.32175670
57GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.31746582
58* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.29998441
59* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.28434977
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28253209
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.27675382
62AR_19668381_ChIP-Seq_PC3_Human1.27006690
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.26360239
64WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25296571
65* NANOG_18555785_Chip-Seq_ESCs_Mouse1.24559455
66RING1B_27294783_Chip-Seq_ESCs_Mouse1.23163939
67BCAT_22108803_ChIP-Seq_LS180_Human1.21743398
68TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.20515396
69SMAD_19615063_ChIP-ChIP_OVARY_Human1.18054649
70KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17793968
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17203423
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16615344
73ZNF274_21170338_ChIP-Seq_K562_Hela1.14467744
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13105142
75SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.11662008
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11173335
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.11054349
78STAT3_23295773_ChIP-Seq_U87_Human1.10171421
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.09796706
80ZFP281_27345836_Chip-Seq_ESCs_Mouse1.09453367
81PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.09175949
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09128346
83AHR_22903824_ChIP-Seq_MCF-7_Human1.09027591
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08518933
85TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.07225527
86RUNX2_22187159_ChIP-Seq_PCA_Human1.06548985
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06482755
88* E2F1_18555785_Chip-Seq_ESCs_Mouse1.05681578
89TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05330731
90CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05300211
91P53_22387025_ChIP-Seq_ESCs_Mouse1.05098215
92BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04708199
93SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04705400
94* CMYC_18555785_Chip-Seq_ESCs_Mouse1.04051854
95BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.03556282
96CDX2_19796622_ChIP-Seq_MESCs_Mouse1.02769614
97PRDM14_20953172_ChIP-Seq_ESCs_Human1.02654483
98SMAD4_21741376_ChIP-Seq_HESCs_Human1.02332920
99SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01653791
100ESR2_21235772_ChIP-Seq_MCF-7_Human1.01473048
101TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01204060
102VDR_22108803_ChIP-Seq_LS180_Human1.01197963
103TET1_21490601_ChIP-Seq_MESCs_Mouse1.00872255
104ARNT_22903824_ChIP-Seq_MCF-7_Human1.00354988
105ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00026760
106NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99875802
107PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99649069
108RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99632339
109CBP_20019798_ChIP-Seq_JUKART_Human0.99486544
110IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.99486544
111CTCF_27219007_Chip-Seq_Bcells_Human0.99335285
112TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99182226
113AR_25329375_ChIP-Seq_VCAP_Human0.99143545
114VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99079190
115RING1B_27294783_Chip-Seq_NPCs_Mouse0.98796966
116* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.98505218
117CBX2_27304074_Chip-Seq_ESCs_Mouse0.98296723
118DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.98230697
119PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97339509
120SMAD3_21741376_ChIP-Seq_HESCs_Human0.96267680
121CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.95860341
122* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95424067
123YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94859914
124TAF15_26573619_Chip-Seq_HEK293_Human0.93564037
125CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92263695
126P53_22127205_ChIP-Seq_FIBROBLAST_Human0.92009855
127TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91517251
128TCF4_23295773_ChIP-Seq_U87_Human0.91324219
129SMAD3_21741376_ChIP-Seq_ESCs_Human0.91161056
130RXR_22108803_ChIP-Seq_LS180_Human0.91087414
131LXR_22292898_ChIP-Seq_THP-1_Human0.90111486
132SMAD3_21741376_ChIP-Seq_EPCs_Human0.89978634
133TP53_16413492_ChIP-PET_HCT116_Human0.89788590
134KDM2B_26808549_Chip-Seq_DND41_Human0.89628922
135ESR1_20079471_ChIP-ChIP_T-47D_Human0.88959591
136KLF4_19829295_ChIP-Seq_ESCs_Human0.88133786
137MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87860599
138KDM2B_26808549_Chip-Seq_JURKAT_Human0.86986780
139TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.85353575
140EP300_21415370_ChIP-Seq_HL-1_Mouse0.83538264
141RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.82751047
142PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.82371928
143SMC4_20622854_ChIP-Seq_HELA_Human0.82198690
144PIAS1_25552417_ChIP-Seq_VCAP_Human0.82157760

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.60713665
2MP0003635_abnormal_synaptic_transmissio4.04792020
3MP0003880_abnormal_central_pattern3.88919820
4MP0004270_analgesia3.73466635
5MP0001968_abnormal_touch/_nociception3.42008009
6MP0009745_abnormal_behavioral_response3.21891846
7MP0009046_muscle_twitch3.18270026
8MP0002064_seizures3.10121214
9MP0002063_abnormal_learning/memory/cond3.08961375
10MP0005423_abnormal_somatic_nervous2.80686990
11MP0002734_abnormal_mechanical_nocicepti2.72974130
12MP0002822_catalepsy2.68022213
13MP0002272_abnormal_nervous_system2.56495410
14MP0002572_abnormal_emotion/affect_behav2.55235863
15MP0002736_abnormal_nociception_after2.54651032
16MP0002735_abnormal_chemical_nociception2.53393573
17MP0001486_abnormal_startle_reflex2.32324722
18MP0002733_abnormal_thermal_nociception2.31712852
19MP0004858_abnormal_nervous_system2.28657622
20MP0009780_abnormal_chondrocyte_physiolo2.23292678
21MP0002909_abnormal_adrenal_gland2.19452409
22MP0002638_abnormal_pupillary_reflex2.16006238
23MP0001970_abnormal_pain_threshold2.15216210
24MP0001501_abnormal_sleep_pattern2.12215952
25MP0003329_amyloid_beta_deposits2.10415849
26MP0008569_lethality_at_weaning2.03093112
27MP0001440_abnormal_grooming_behavior1.99031069
28MP0002067_abnormal_sensory_capabilities1.92356702
29MP0008877_abnormal_DNA_methylation1.84899457
30MP0003195_calcinosis1.84832984
31MP0004811_abnormal_neuron_physiology1.79847163
32MP0003121_genomic_imprinting1.66949809
33MP0005386_behavior/neurological_phenoty1.64779382
34MP0004924_abnormal_behavior1.64779382
35MP0002184_abnormal_innervation1.64139795
36MP0003633_abnormal_nervous_system1.62037831
37MP0004885_abnormal_endolymph1.59667526
38MP0002557_abnormal_social/conspecific_i1.53202473
39MP0000955_abnormal_spinal_cord1.53194425
40MP0008961_abnormal_basal_metabolism1.47467680
41MP0006276_abnormal_autonomic_nervous1.44361497
42MP0002653_abnormal_ependyma_morphology1.39006617
43MP0003879_abnormal_hair_cell1.37766158
44MP0002066_abnormal_motor_capabilities/c1.37520312
45MP0005646_abnormal_pituitary_gland1.34989683
46MP0003690_abnormal_glial_cell1.34961350
47MP0000778_abnormal_nervous_system1.33733500
48MP0002882_abnormal_neuron_morphology1.31830171
49MP0003283_abnormal_digestive_organ1.29236456
50MP0005379_endocrine/exocrine_gland_phen1.29159141
51MP0003631_nervous_system_phenotype1.28775949
52MP0000751_myopathy1.28315612
53MP0003123_paternal_imprinting1.25320210
54MP0000569_abnormal_digit_pigmentation1.24001300
55MP0005167_abnormal_blood-brain_barrier1.20824112
56MP0005645_abnormal_hypothalamus_physiol1.19112608
57MP0003075_altered_response_to1.15993322
58MP0000013_abnormal_adipose_tissue1.15961762
59MP0002928_abnormal_bile_duct1.15141824
60MP0000604_amyloidosis1.13771317
61MP0008874_decreased_physiological_sensi1.12126991
62MP0002229_neurodegeneration1.11664574
63MP0001502_abnormal_circadian_rhythm1.11245342
64MP0001984_abnormal_olfaction1.10399463
65MP0005084_abnormal_gallbladder_morpholo1.09700525
66MP0003172_abnormal_lysosome_physiology1.08838364
67MP0003787_abnormal_imprinting1.06713105
68MP0002837_dystrophic_cardiac_calcinosis1.06534672
69MP0003122_maternal_imprinting1.05038596
70MP0004142_abnormal_muscle_tone1.04845473
71MP0002102_abnormal_ear_morphology1.04765988
72MP0001986_abnormal_taste_sensitivity1.04209870
73MP0008872_abnormal_physiological_respon1.03176146
74MP0002876_abnormal_thyroid_physiology1.02355528
75MP0004130_abnormal_muscle_cell1.02213315
76MP0004145_abnormal_muscle_electrophysio1.00289858
77MP0005535_abnormal_body_temperature1.00079545
78MP0003634_abnormal_glial_cell0.99462447
79MP0004133_heterotaxia0.98429315
80MP0005551_abnormal_eye_electrophysiolog0.96057863
81MP0000920_abnormal_myelination0.95972449
82MP0004085_abnormal_heartbeat0.94901218
83MP0002152_abnormal_brain_morphology0.94557139
84MP0004215_abnormal_myocardial_fiber0.93795733
85MP0003632_abnormal_nervous_system0.91506147
86MP0005253_abnormal_eye_physiology0.90524164
87MP0002069_abnormal_eating/drinking_beha0.89908349
88MP0002090_abnormal_vision0.88587975
89MP0000631_abnormal_neuroendocrine_gland0.87006529
90MP0003252_abnormal_bile_duct0.85866268
91MP0001177_atelectasis0.84836579
92MP0004510_myositis0.83797520
93MP0010234_abnormal_vibrissa_follicle0.83054424
94MP0003045_fibrosis0.82782913
95MP0000747_muscle_weakness0.81868753
96MP0004043_abnormal_pH_regulation0.81685648
97MP0001905_abnormal_dopamine_level0.80879864
98MP0003137_abnormal_impulse_conducting0.78960139
99MP0005220_abnormal_exocrine_pancreas0.78682156
100MP0001485_abnormal_pinna_reflex0.77819402
101MP0001944_abnormal_pancreas_morphology0.76756084
102MP0002693_abnormal_pancreas_physiology0.75783180
103MP0010329_abnormal_lipoprotein_level0.75459812
104MP0004233_abnormal_muscle_weight0.71737181
105MP0005623_abnormal_meninges_morphology0.71089621
106MP0004484_altered_response_of0.69837798
107MP0010386_abnormal_urinary_bladder0.68735334
108MP0006072_abnormal_retinal_apoptosis0.67089839
109MP0005171_absent_coat_pigmentation0.66883898
110MP0002163_abnormal_gland_morphology0.66285167
111MP0001299_abnormal_eye_distance/0.66155748
112MP0004036_abnormal_muscle_relaxation0.64260022
113MP0001756_abnormal_urination0.63331390
114MP0002752_abnormal_somatic_nervous0.57071394
115MP0001529_abnormal_vocalization0.55031145
116MP0005187_abnormal_penis_morphology0.54587964
117MP0004742_abnormal_vestibular_system0.53159998
118MP0004084_abnormal_cardiac_muscle0.52746831
119MP0001963_abnormal_hearing_physiology0.51337943
120MP0005166_decreased_susceptibility_to0.51125361
121MP0001943_abnormal_respiration0.50092383
122MP0003183_abnormal_peptide_metabolism0.47830279
123* MP0010769_abnormal_survival0.47649813
124MP0003956_abnormal_body_size0.47499146
125MP0000003_abnormal_adipose_tissue0.47109644

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.44053735
2Focal motor seizures (HP:0011153)6.22777153
3Focal seizures (HP:0007359)5.25530204
4Visual hallucinations (HP:0002367)5.13170902
5Action tremor (HP:0002345)4.68350237
6Progressive cerebellar ataxia (HP:0002073)4.05072925
7Supranuclear gaze palsy (HP:0000605)4.03747139
8Atonic seizures (HP:0010819)3.79420925
9Ankle clonus (HP:0011448)3.68565402
10Febrile seizures (HP:0002373)3.66662651
11Absence seizures (HP:0002121)3.66364750
12Epileptic encephalopathy (HP:0200134)3.63884289
13Generalized tonic-clonic seizures (HP:0002069)3.57852200
14Depression (HP:0000716)3.43314854
15Postural instability (HP:0002172)3.36972108
16Papilledema (HP:0001085)3.36850303
17Dialeptic seizures (HP:0011146)3.33081697
18Abnormality of the lower motor neuron (HP:0002366)3.32123545
19Urinary bladder sphincter dysfunction (HP:0002839)3.22335263
20Dysdiadochokinesis (HP:0002075)3.21418083
21Impaired vibration sensation in the lower limbs (HP:0002166)3.19592790
22Poor eye contact (HP:0000817)3.19509244
23Polyphagia (HP:0002591)3.19270957
24Ventricular fibrillation (HP:0001663)3.15969408
25Impaired social interactions (HP:0000735)3.12116026
26Abnormal social behavior (HP:0012433)3.12116026
27Truncal ataxia (HP:0002078)3.10785569
28Hemiplegia (HP:0002301)3.05780987
29Dysmetria (HP:0001310)3.04953779
30Gaze-evoked nystagmus (HP:0000640)2.96879731
31Mutism (HP:0002300)2.91389353
32Urinary urgency (HP:0000012)2.89870570
33Intention tremor (HP:0002080)2.89459923
34Dysmetric saccades (HP:0000641)2.88433380
35Anxiety (HP:0000739)2.84980687
36Abnormal eating behavior (HP:0100738)2.83020708
37Impaired smooth pursuit (HP:0007772)2.73688981
38Broad-based gait (HP:0002136)2.73084187
39Spastic gait (HP:0002064)2.66570930
40Termporal pattern (HP:0011008)2.66090087
41Insidious onset (HP:0003587)2.66090087
42Genetic anticipation (HP:0003743)2.65891819
43Scanning speech (HP:0002168)2.65716362
44Bundle branch block (HP:0011710)2.62012580
45Neurofibrillary tangles (HP:0002185)2.61690036
46Torticollis (HP:0000473)2.59809363
47Cerebral inclusion bodies (HP:0100314)2.58578151
48Increased circulating renin level (HP:0000848)2.57864504
49Status epilepticus (HP:0002133)2.57029496
50Pheochromocytoma (HP:0002666)2.54389708
51Insomnia (HP:0100785)2.52439995
52Bradykinesia (HP:0002067)2.52293536
53Abnormality of ocular smooth pursuit (HP:0000617)2.48453883
54Abnormality of binocular vision (HP:0011514)2.38702354
55Diplopia (HP:0000651)2.38702354
56Annular pancreas (HP:0001734)2.37965209
57Hyperinsulinemic hypoglycemia (HP:0000825)2.36811801
58Generalized hypopigmentation of hair (HP:0011358)2.36436493
59Hemiparesis (HP:0001269)2.36180905
60Hematochezia (HP:0002573)2.35846946
61Focal dystonia (HP:0004373)2.33063698
62Abnormality of the corticospinal tract (HP:0002492)2.32109560
63Lower limb muscle weakness (HP:0007340)2.30821216
64Neuronal loss in central nervous system (HP:0002529)2.30427338
65Absent speech (HP:0001344)2.25757484
66Amblyopia (HP:0000646)2.23346687
67Hypoglycemic seizures (HP:0002173)2.22562701
68Resting tremor (HP:0002322)2.22335516
69Rapidly progressive (HP:0003678)2.22148206
70Clonus (HP:0002169)2.20873944
71Pointed chin (HP:0000307)2.20801990
72Progressive inability to walk (HP:0002505)2.20089905
73Polydipsia (HP:0001959)2.18772351
74Abnormal drinking behavior (HP:0030082)2.18772351
75Megalencephaly (HP:0001355)2.17654082
76Tetraplegia (HP:0002445)2.17247235
77Impaired vibratory sensation (HP:0002495)2.17074287
78Gait imbalance (HP:0002141)2.16405542
79Postural tremor (HP:0002174)2.15491401
80Excessive salivation (HP:0003781)2.14435890
81Drooling (HP:0002307)2.14435890
82Hypomagnesemia (HP:0002917)2.12529684
83Craniofacial dystonia (HP:0012179)2.12093696
84Macroorchidism (HP:0000053)2.10976656
85Agitation (HP:0000713)2.10666369
86Hypothermia (HP:0002045)2.09565694
87Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.08582546
88Iris hypopigmentation (HP:0007730)2.07053884
89Neuroendocrine neoplasm (HP:0100634)2.06697535
90Stereotypic behavior (HP:0000733)2.05909244
91Abnormal EKG (HP:0003115)2.04219430
92Rigidity (HP:0002063)2.02288649
93Abnormality of saccadic eye movements (HP:0000570)2.01825764
94Increased CSF protein (HP:0002922)2.00542652
95Hyperventilation (HP:0002883)1.99244158
96Epileptiform EEG discharges (HP:0011182)1.98096976
97EEG with generalized epileptiform discharges (HP:0011198)1.97659704
98Medial flaring of the eyebrow (HP:0010747)1.97262432
99Blue irides (HP:0000635)1.96686435
100Hypercortisolism (HP:0001578)1.94775771
101Aqueductal stenosis (HP:0002410)1.94466208
102Gait ataxia (HP:0002066)1.94439399
103Akinesia (HP:0002304)1.94310839
104Hypsarrhythmia (HP:0002521)1.92925805
105Prolonged QT interval (HP:0001657)1.91981450
106Fair hair (HP:0002286)1.91577692
107Hypoglycemic coma (HP:0001325)1.90037659
108Psychosis (HP:0000709)1.89324173
109Nephronophthisis (HP:0000090)1.89209431
110Hepatoblastoma (HP:0002884)1.88538025
111Abnormality of pain sensation (HP:0010832)1.87195836
112Impaired pain sensation (HP:0007328)1.87195836
113Muscular hypotonia of the trunk (HP:0008936)1.86060088
114Ocular albinism (HP:0001107)1.85352689
115Congenital stationary night blindness (HP:0007642)1.85105510
116Neoplasm of the heart (HP:0100544)1.84945798
117Spastic tetraplegia (HP:0002510)1.83485225
118Lower limb amyotrophy (HP:0007210)1.83038048
119Generalized myoclonic seizures (HP:0002123)1.81354956
120Enlarged penis (HP:0000040)1.80581899
121Specific learning disability (HP:0001328)1.79795281
122Limb dystonia (HP:0002451)1.79551124
123Lower limb asymmetry (HP:0100559)1.78955166
124Syncope (HP:0001279)1.78399460
125Neoplasm of the adrenal cortex (HP:0100641)1.78349769
126Hammertoe (HP:0001765)1.78144887
127Thyroiditis (HP:0100646)1.77905010
128Amyotrophic lateral sclerosis (HP:0007354)1.77690122
129Abnormality of the periventricular white matter (HP:0002518)1.76715670
130Hyperacusis (HP:0010780)1.76602622
131Spastic tetraparesis (HP:0001285)1.76477159
132Pancreatic fibrosis (HP:0100732)1.72445407
133Congenital primary aphakia (HP:0007707)1.70798962
134Failure to thrive in infancy (HP:0001531)1.70567491
135Morphological abnormality of the pyramidal tract (HP:0002062)1.68986833
136Abnormality of macular pigmentation (HP:0008002)1.68659554
137Ulnar claw (HP:0001178)1.67441617
138Abnormality of the pancreatic islet cells (HP:0006476)1.67034727
139Abnormality of endocrine pancreas physiology (HP:0012093)1.67034727
140Intestinal atresia (HP:0011100)1.65880374

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.47093034
2MAP3K94.32349983
3NTRK34.16258420
4EPHA43.22624561
5CASK3.18870018
6MAP3K42.72363731
7KSR22.59328349
8MINK12.54816620
9NTRK12.49509220
10PAK62.47934698
11MARK12.44901634
12DAPK22.40463538
13PRKD32.36351562
14CAMKK12.14736023
15NTRK22.04739963
16MAP2K41.93679716
17STK381.81158465
18RIPK41.80761488
19MAP2K71.80240098
20BMPR1B1.69000597
21MAP4K21.62359773
22MAP3K21.60185532
23STK38L1.56070165
24LMTK21.52628452
25WNK31.52316719
26GRK51.48196148
27CDK51.47443127
28TYRO31.40836276
29SIK21.38175867
30RET1.33782994
31RIPK11.31110936
32PRKCH1.29658037
33MAP3K131.25929530
34TIE11.23959627
35PHKG21.23450936
36PHKG11.23450936
37MAP3K121.23340764
38ALK1.19013423
39KSR11.16969201
40FGFR31.15908109
41FES1.15002496
42LATS21.12557080
43DAPK11.12112196
44CAMKK21.10768803
45UHMK11.10395137
46PINK11.09257457
47TAOK11.07562757
48SGK4941.05052037
49SGK2231.05052037
50BRD41.04912067
51SGK31.04353801
52ADRBK21.03779404
53PRKCG1.03330523
54CAMK10.97973126
55ARAF0.95164757
56TRIB30.95016692
57STK110.94613728
58CAMK1G0.94561088
59SCYL20.93721624
60CSNK1G10.93525784
61BCR0.93066574
62WNK10.91375716
63SGK20.89903511
64PNCK0.89253193
65PDK10.88900512
66EPHA30.88611168
67MAP3K10.87729729
68CSNK1G30.85793961
69NLK0.85484955
70PAK30.84150317
71PRPF4B0.83145383
72PDPK10.80607136
73NEK10.78862464
74MAP3K70.78320534
75CDC42BPA0.76735445
76MARK20.76605998
77CAMK2A0.76428298
78ACVR1B0.76112979
79STK390.75387460
80CDK150.73816651
81CDK180.71480240
82CDK140.71405947
83ITK0.71113621
84INSRR0.70293470
85TNK20.70293168
86MAPK130.68340531
87CSNK1A1L0.67420192
88PKN20.67410920
89PDGFRA0.66524553
90SGK10.65506986
91GRK10.65493081
92PLK20.65426172
93ERBB20.65094194
94CDK190.64473565
95CDK11A0.61655772
96FGFR20.58924696
97CAMK40.58699428
98PTK2B0.56750886
99RPS6KA30.56261733
100CAMK2B0.54988912
101SYK0.53726660
102CSNK1D0.53652529
103CSNK1G20.53337767
104PRKCZ0.52630961
105FYN0.52003386
106FER0.51941797
107RAF10.51720749
108TNIK0.51094345
109MAPK100.50873508
110PKN10.50555929
111STK240.49464874
112PRKAA10.49114636
113DMPK0.46270672
114PRKG10.43833727
115FGR0.43528189
116ERBB30.43388825
117MAP2K10.43384493
118EPHB10.43231836
119RPS6KA20.43139408
120BLK0.43119069
121AKT30.42439826
122CAMK2D0.42011559
123DYRK1A0.41977946
124CAMK2G0.41967918
125PRKACA0.40803967
126CAMK1D0.40724940
127BMX0.40243979
128ROCK20.39294494
129TRIM280.39229231
130PRKD10.37583324
131ICK0.37579525
132JAK10.34900495
133OXSR10.32809351
134PRKCE0.32724592
135JAK20.32195103
136PRKCB0.31589971

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.02283926
2Nicotine addiction_Homo sapiens_hsa050332.91856766
3GABAergic synapse_Homo sapiens_hsa047272.49045371
4Olfactory transduction_Homo sapiens_hsa047402.46950154
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.45049385
6Nitrogen metabolism_Homo sapiens_hsa009102.44948553
7Circadian entrainment_Homo sapiens_hsa047132.36871891
8Long-term potentiation_Homo sapiens_hsa047202.33105983
9Glutamatergic synapse_Homo sapiens_hsa047242.26040868
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.20154386
11Morphine addiction_Homo sapiens_hsa050322.16903734
12Salivary secretion_Homo sapiens_hsa049702.01932646
13Insulin secretion_Homo sapiens_hsa049111.99845966
14Amphetamine addiction_Homo sapiens_hsa050311.99739111
15Dopaminergic synapse_Homo sapiens_hsa047281.87018016
16Gastric acid secretion_Homo sapiens_hsa049711.86010999
17Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.84494375
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.76463315
19Cholinergic synapse_Homo sapiens_hsa047251.73752931
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68926437
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.66642385
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.64681913
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.58764837
24Renin secretion_Homo sapiens_hsa049241.48337992
25Taste transduction_Homo sapiens_hsa047421.47780594
26Type II diabetes mellitus_Homo sapiens_hsa049301.47482594
27Oxytocin signaling pathway_Homo sapiens_hsa049211.45261160
28Cocaine addiction_Homo sapiens_hsa050301.43050784
29Long-term depression_Homo sapiens_hsa047301.42003355
30GnRH signaling pathway_Homo sapiens_hsa049121.37016654
31Calcium signaling pathway_Homo sapiens_hsa040201.34721640
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25930831
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.25387859
34Gap junction_Homo sapiens_hsa045401.22137853
35Serotonergic synapse_Homo sapiens_hsa047261.21105761
36Estrogen signaling pathway_Homo sapiens_hsa049151.19112145
37* Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17568439
38cAMP signaling pathway_Homo sapiens_hsa040241.17448513
39Glioma_Homo sapiens_hsa052141.11903565
40Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.10359669
41Regulation of autophagy_Homo sapiens_hsa041401.09105879
42Dorso-ventral axis formation_Homo sapiens_hsa043201.04862280
43Bile secretion_Homo sapiens_hsa049760.99757014
44cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98432106
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98366746
46Phospholipase D signaling pathway_Homo sapiens_hsa040720.95722123
47Collecting duct acid secretion_Homo sapiens_hsa049660.90826341
48ErbB signaling pathway_Homo sapiens_hsa040120.90533089
49Thyroid hormone synthesis_Homo sapiens_hsa049180.89546633
50Pancreatic secretion_Homo sapiens_hsa049720.89374660
51Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89105563
52Melanogenesis_Homo sapiens_hsa049160.88350669
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.86250547
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.85917735
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.85092799
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84314477
57Arginine biosynthesis_Homo sapiens_hsa002200.84075441
58Dilated cardiomyopathy_Homo sapiens_hsa054140.83531119
59Glycosaminoglycan degradation_Homo sapiens_hsa005310.80969096
60mTOR signaling pathway_Homo sapiens_hsa041500.80967225
61Phototransduction_Homo sapiens_hsa047440.79165903
62ABC transporters_Homo sapiens_hsa020100.77710722
63Cardiac muscle contraction_Homo sapiens_hsa042600.76488699
64Axon guidance_Homo sapiens_hsa043600.76106827
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.74267835
66Choline metabolism in cancer_Homo sapiens_hsa052310.71726433
67Ether lipid metabolism_Homo sapiens_hsa005650.70017015
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68458256
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68426356
70VEGF signaling pathway_Homo sapiens_hsa043700.67228183
71Glucagon signaling pathway_Homo sapiens_hsa049220.65619388
72Oocyte meiosis_Homo sapiens_hsa041140.64602864
73MAPK signaling pathway_Homo sapiens_hsa040100.63671513
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63197915
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62645442
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62610954
77Inositol phosphate metabolism_Homo sapiens_hsa005620.61017831
78Sphingolipid metabolism_Homo sapiens_hsa006000.60507161
79Insulin signaling pathway_Homo sapiens_hsa049100.60272963
80Endocytosis_Homo sapiens_hsa041440.60136883
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59367472
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58845853
83Vibrio cholerae infection_Homo sapiens_hsa051100.56799995
84Rap1 signaling pathway_Homo sapiens_hsa040150.56640990
85Prion diseases_Homo sapiens_hsa050200.53291736
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.53191994
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53009183
88Non-small cell lung cancer_Homo sapiens_hsa052230.52115416
89Platelet activation_Homo sapiens_hsa046110.51178195
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50930709
91Endometrial cancer_Homo sapiens_hsa052130.50081448
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.49468024
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48769679
94Vitamin B6 metabolism_Homo sapiens_hsa007500.47443802
95Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47221679
96Ras signaling pathway_Homo sapiens_hsa040140.46294515
97Peroxisome_Homo sapiens_hsa041460.43756272
98Lysosome_Homo sapiens_hsa041420.43155516
99Renal cell carcinoma_Homo sapiens_hsa052110.41902772
100Type I diabetes mellitus_Homo sapiens_hsa049400.41353328
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.40922960
102Butanoate metabolism_Homo sapiens_hsa006500.39171038
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38993627
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38668513
105Mineral absorption_Homo sapiens_hsa049780.38486526
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37243616
107Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37065020
108Fatty acid biosynthesis_Homo sapiens_hsa000610.36828297
109Chemokine signaling pathway_Homo sapiens_hsa040620.36396804
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.35415404
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.34996943
112Circadian rhythm_Homo sapiens_hsa047100.34612574
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.34186027
114Linoleic acid metabolism_Homo sapiens_hsa005910.33657228
115Prolactin signaling pathway_Homo sapiens_hsa049170.33181810
116Insulin resistance_Homo sapiens_hsa049310.32503845
117Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32068754
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.31782705
119Complement and coagulation cascades_Homo sapiens_hsa046100.31256737
120Ovarian steroidogenesis_Homo sapiens_hsa049130.30918143
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30416071

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