Rank | Gene Set | Z-score |
---|---|---|
1 | intestinal epithelial cell development (GO:0060576) | 8.10377013 |
2 | regulation of guanylate cyclase activity (GO:0031282) | 7.44236715 |
3 | interferon-gamma secretion (GO:0072643) | 7.30381127 |
4 | intestinal absorption (GO:0050892) | 6.29601932 |
5 | positive regulation of respiratory burst (GO:0060267) | 5.77199239 |
6 | positive regulation of guanylate cyclase activity (GO:0031284) | 5.32298898 |
7 | epoxygenase P450 pathway (GO:0019373) | 5.28455094 |
8 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 5.25425261 |
9 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 5.25425261 |
10 | endocrine process (GO:0050886) | 5.25425261 |
11 | modified amino acid transport (GO:0072337) | 5.24974726 |
12 | regulation of cellular extravasation (GO:0002691) | 5.20836225 |
13 | folic acid metabolic process (GO:0046655) | 5.11284430 |
14 | renal system process involved in regulation of blood volume (GO:0001977) | 5.04833320 |
15 | intestinal cholesterol absorption (GO:0030299) | 4.96649876 |
16 | GDP-mannose metabolic process (GO:0019673) | 4.91391919 |
17 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.90370708 |
18 | pyrimidine nucleoside salvage (GO:0043097) | 4.84190997 |
19 | pyrimidine-containing compound salvage (GO:0008655) | 4.84190997 |
20 | regulation of systemic arterial blood pressure (GO:0003073) | 4.76978221 |
21 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.75068745 |
22 | folic acid transport (GO:0015884) | 4.73369045 |
23 | flavonoid metabolic process (GO:0009812) | 4.58236154 |
24 | regulation of cGMP biosynthetic process (GO:0030826) | 4.52394017 |
25 | lipoprotein transport (GO:0042953) | 4.52297930 |
26 | nucleoside salvage (GO:0043174) | 4.51295420 |
27 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 4.44765977 |
28 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.40342460 |
29 | hepatocyte apoptotic process (GO:0097284) | 4.39555591 |
30 | glomerular filtration (GO:0003094) | 4.37056867 |
31 | regulation of vitamin metabolic process (GO:0030656) | 4.36742065 |
32 | diacylglycerol metabolic process (GO:0046339) | 4.34725209 |
33 | urea cycle (GO:0000050) | 4.30398358 |
34 | regulation of respiratory burst (GO:0060263) | 4.22956165 |
35 | angiotensin maturation (GO:0002003) | 4.21643820 |
36 | regulation of water loss via skin (GO:0033561) | 4.17263615 |
37 | hormone catabolic process (GO:0042447) | 4.16630306 |
38 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 4.14676730 |
39 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.10804132 |
40 | urea metabolic process (GO:0019627) | 4.05329791 |
41 | regulation of cholesterol homeostasis (GO:2000188) | 4.05285546 |
42 | drug metabolic process (GO:0017144) | 3.99856490 |
43 | galactose catabolic process (GO:0019388) | 3.99636642 |
44 | renal filtration (GO:0097205) | 3.96660699 |
45 | ethanol oxidation (GO:0006069) | 3.96378171 |
46 | oligosaccharide catabolic process (GO:0009313) | 3.95435220 |
47 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.92608926 |
48 | desmosome organization (GO:0002934) | 3.88639059 |
49 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.83513381 |
50 | actin filament depolymerization (GO:0030042) | 3.80305162 |
51 | regulation of cardioblast differentiation (GO:0051890) | 3.79283259 |
52 | oligosaccharide biosynthetic process (GO:0009312) | 3.79088968 |
53 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.74388276 |
54 | cGMP-mediated signaling (GO:0019934) | 3.71381341 |
55 | nitrogen cycle metabolic process (GO:0071941) | 3.70729202 |
56 | establishment of skin barrier (GO:0061436) | 3.70661797 |
57 | ribosomal small subunit biogenesis (GO:0042274) | 3.69840329 |
58 | regulation of cGMP metabolic process (GO:0030823) | 3.69007323 |
59 | CDP-diacylglycerol metabolic process (GO:0046341) | 3.65353100 |
60 | adhesion of symbiont to host cell (GO:0044650) | 3.64387460 |
61 | virion attachment to host cell (GO:0019062) | 3.64387460 |
62 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 3.62334140 |
63 | positive regulation of pseudopodium assembly (GO:0031274) | 3.61312021 |
64 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 3.61211330 |
65 | purine nucleobase biosynthetic process (GO:0009113) | 3.58080093 |
66 | plasma lipoprotein particle assembly (GO:0034377) | 3.57304458 |
67 | glycosphingolipid catabolic process (GO:0046479) | 3.56607006 |
68 | regulation of translation in response to stress (GO:0043555) | 3.56048417 |
69 | vitamin transmembrane transport (GO:0035461) | 3.53708302 |
70 | glycolipid catabolic process (GO:0019377) | 3.52488976 |
71 | cell differentiation involved in embryonic placenta development (GO:0060706) | 3.52324800 |
72 | peptide catabolic process (GO:0043171) | 3.51766755 |
73 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.51255299 |
74 | nucleoside diphosphate biosynthetic process (GO:0009133) | 3.49603202 |
75 | auditory receptor cell differentiation (GO:0042491) | 3.49545078 |
76 | epithelial structure maintenance (GO:0010669) | 3.49403736 |
77 | fructose metabolic process (GO:0006000) | 3.46291033 |
78 | positive regulation of glycoprotein metabolic process (GO:1903020) | 3.42828095 |
79 | regulation of histone H3-K27 methylation (GO:0061085) | 3.41922538 |
80 | glucocorticoid biosynthetic process (GO:0006704) | 3.40401900 |
81 | ribosome assembly (GO:0042255) | 3.39361568 |
82 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.38547849 |
83 | peptide hormone processing (GO:0016486) | 3.36346872 |
84 | maintenance of gastrointestinal epithelium (GO:0030277) | 3.36132809 |
85 | maturation of SSU-rRNA (GO:0030490) | 3.35062107 |
86 | regulation of pseudopodium assembly (GO:0031272) | 3.34684797 |
87 | transcytosis (GO:0045056) | 3.34236133 |
88 | heme transport (GO:0015886) | 3.33361335 |
89 | protein-lipid complex assembly (GO:0065005) | 3.32982381 |
90 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.31009740 |
91 | glutamine family amino acid biosynthetic process (GO:0009084) | 3.28823981 |
92 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.27933645 |
93 | DNA damage response, detection of DNA damage (GO:0042769) | 3.25814043 |
94 | proteasome assembly (GO:0043248) | 3.20895160 |
95 | sulfate transmembrane transport (GO:1902358) | 3.20417852 |
96 | DNA deamination (GO:0045006) | 3.19897098 |
97 | arginine metabolic process (GO:0006525) | 3.18849467 |
98 | O-glycan processing (GO:0016266) | 3.18624304 |
99 | vitamin A metabolic process (GO:0006776) | 3.17044162 |
100 | digestion (GO:0007586) | 3.16621003 |
101 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.16452437 |
102 | nucleobase biosynthetic process (GO:0046112) | 3.15033183 |
103 | adhesion of symbiont to host (GO:0044406) | 3.14352620 |
104 | NADH metabolic process (GO:0006734) | 3.14336469 |
105 | anterior/posterior axis specification, embryo (GO:0008595) | 3.14177020 |
106 | tight junction assembly (GO:0070830) | 3.13461584 |
107 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.10110091 |
108 | positive regulation of cGMP biosynthetic process (GO:0030828) | 3.06662979 |
109 | ethanol metabolic process (GO:0006067) | 3.06134725 |
110 | positive regulation of lipid catabolic process (GO:0050996) | 3.04217003 |
111 | sulfur compound transport (GO:0072348) | 3.03852118 |
112 | sulfate transport (GO:0008272) | 3.03531675 |
113 | homocysteine metabolic process (GO:0050667) | 3.02997877 |
114 | thrombin receptor signaling pathway (GO:0070493) | 3.01517213 |
115 | glucose 6-phosphate metabolic process (GO:0051156) | 3.01092177 |
116 | fucosylation (GO:0036065) | 3.00515834 |
117 | cellular glucuronidation (GO:0052695) | 2.98958694 |
118 | ADP metabolic process (GO:0046031) | 2.98448553 |
119 | digestive system process (GO:0022600) | 2.98048451 |
120 | formation of translation preinitiation complex (GO:0001731) | 2.96450714 |
121 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.96350761 |
122 | cellular response to nitric oxide (GO:0071732) | 2.95874410 |
123 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 2.95854176 |
124 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.95122330 |
125 | viral transcription (GO:0019083) | 2.94372282 |
126 | glycosylceramide metabolic process (GO:0006677) | 2.93587995 |
127 | sphingolipid catabolic process (GO:0030149) | 2.93466101 |
128 | complement activation, classical pathway (GO:0006958) | 2.92844510 |
129 | drug transport (GO:0015893) | 2.91830455 |
130 | eosinophil chemotaxis (GO:0048245) | 2.90586719 |
131 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.90530922 |
132 | response to nitric oxide (GO:0071731) | 2.89701789 |
133 | translational termination (GO:0006415) | 2.88878523 |
134 | alkaloid metabolic process (GO:0009820) | 2.88871274 |
135 | diol metabolic process (GO:0034311) | 2.88487665 |
136 | sphingomyelin metabolic process (GO:0006684) | 2.87524586 |
137 | keratinocyte development (GO:0003334) | 2.86977046 |
138 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 2.81424288 |
139 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 2.79958584 |
140 | antibacterial humoral response (GO:0019731) | 2.79321914 |
141 | translational initiation (GO:0006413) | 2.76838787 |
142 | respiratory tube development (GO:0030323) | 2.75983072 |
143 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.75586786 |
144 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.75439533 |
145 | * trophectodermal cell differentiation (GO:0001829) | 2.74981054 |
146 | lung-associated mesenchyme development (GO:0060484) | 2.74304062 |
147 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.73410431 |
148 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 2.73278987 |
149 | antimicrobial humoral response (GO:0019730) | 2.72771169 |
150 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.71647656 |
151 | nucleotide-sugar metabolic process (GO:0009225) | 2.71626981 |
152 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.71529602 |
153 | regulation of gene silencing by miRNA (GO:0060964) | 2.71529602 |
154 | regulation of gene silencing by RNA (GO:0060966) | 2.71529602 |
155 | regulation of bile acid biosynthetic process (GO:0070857) | 2.71184628 |
156 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.70614556 |
157 | inner cell mass cell proliferation (GO:0001833) | 2.69396154 |
158 | ribosomal large subunit biogenesis (GO:0042273) | 2.68824811 |
159 | uterus development (GO:0060065) | 2.68754197 |
160 | vitamin transport (GO:0051180) | 2.67427220 |
161 | sulfur amino acid catabolic process (GO:0000098) | 2.67289865 |
162 | cyclooxygenase pathway (GO:0019371) | 2.67023299 |
163 | columnar/cuboidal epithelial cell development (GO:0002066) | 2.66619899 |
164 | uronic acid metabolic process (GO:0006063) | 2.64112128 |
165 | glucuronate metabolic process (GO:0019585) | 2.64112128 |
166 | bile acid and bile salt transport (GO:0015721) | 2.63576418 |
167 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.63100052 |
168 | positive regulation of epidermal cell differentiation (GO:0045606) | 2.62465058 |
169 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.61409104 |
170 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.61409104 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.40505634 |
2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.12960378 |
3 | * CDX2_20551321_ChIP-Seq_CACO-2_Human | 3.00288592 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.88011775 |
5 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.83102938 |
6 | * CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.77517114 |
7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.75654993 |
8 | * SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.48484619 |
9 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.47176386 |
10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.43872510 |
11 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 2.41887586 |
12 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.40632388 |
13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.26016957 |
14 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.25169954 |
15 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.23266216 |
16 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.23238881 |
17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.21466430 |
18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.20580512 |
19 | * POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.18153346 |
20 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 2.16413901 |
21 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.15184404 |
22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.12387017 |
23 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.07627178 |
24 | * NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.06679007 |
25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.06586079 |
26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.02793512 |
27 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.99538211 |
28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.99219641 |
29 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.98911440 |
30 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.95528559 |
31 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.94448707 |
32 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.89798167 |
33 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 1.85928444 |
34 | * TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.85198465 |
35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.83781011 |
36 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.82458045 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.82433117 |
38 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.81264099 |
39 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.80729640 |
40 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.79741668 |
41 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.78741836 |
42 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.76099424 |
43 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.76089902 |
44 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.74470593 |
45 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.74101273 |
46 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.72547015 |
47 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.72101819 |
48 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.70293926 |
49 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.70293926 |
50 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.70293926 |
51 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.69818636 |
52 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.67444441 |
53 | ATF3_27146783_Chip-Seq_COLON_Human | 1.66375688 |
54 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.65834203 |
55 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.64480409 |
56 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.59804234 |
57 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.54226999 |
58 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.52778377 |
59 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.52692918 |
60 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.52538002 |
61 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.50610008 |
62 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.50295438 |
63 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.49570131 |
64 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.48149833 |
65 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.47161681 |
66 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.45239161 |
67 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.44825488 |
68 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.44330515 |
69 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.41783163 |
70 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.41016053 |
71 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.39997775 |
72 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39888146 |
73 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.39366473 |
74 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.38808589 |
75 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.37470587 |
76 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.36952188 |
77 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.36689693 |
78 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.35432766 |
79 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.33747519 |
80 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.32787820 |
81 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.30971488 |
82 | * JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 1.30321335 |
83 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.30229906 |
84 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.29756267 |
85 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.29520385 |
86 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.26721723 |
87 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.25552849 |
88 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.24612555 |
89 | * SA1_27219007_Chip-Seq_Bcells_Human | 1.23303732 |
90 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.22495024 |
91 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.20706512 |
92 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19995368 |
93 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.18763646 |
94 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.18476147 |
95 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.17694567 |
96 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.17066264 |
97 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.17054531 |
98 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15934845 |
99 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.15041564 |
100 | * AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.14883861 |
101 | * TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.12651872 |
102 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.11966742 |
103 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.11230551 |
104 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.10841452 |
105 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.09740126 |
106 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.08869543 |
107 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07846517 |
108 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.07547335 |
109 | * POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 1.07088173 |
110 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.06585555 |
111 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06168891 |
112 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.05824105 |
113 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.03937778 |
114 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.02850475 |
115 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.02669546 |
116 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.02179846 |
117 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.01289987 |
118 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.00862028 |
119 | * FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.00803003 |
120 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00761547 |
121 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.00694588 |
122 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.00563928 |
123 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.99513163 |
124 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.98597899 |
125 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.98373469 |
126 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.97859785 |
127 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.97700293 |
128 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.97404007 |
129 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.97284255 |
130 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.97170856 |
131 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.97156744 |
132 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.96765025 |
133 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.96687569 |
134 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.95917523 |
135 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95778644 |
136 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.95712331 |
137 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.95465860 |
138 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.95202792 |
139 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.94841764 |
140 | * NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.94328093 |
141 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93685075 |
142 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.93596783 |
143 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.93207114 |
144 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.93178052 |
145 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.92945730 |
146 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.92152253 |
147 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.91254972 |
148 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91045052 |
149 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.90651939 |
150 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.90642050 |
151 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.90334602 |
152 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.89992786 |
153 | * POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.89783692 |
154 | P68_20966046_ChIP-Seq_HELA_Human | 0.89575029 |
155 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.89397221 |
156 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.89274690 |
157 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 0.89186839 |
158 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.88719392 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009840_abnormal_foam_cell | 4.69761991 |
2 | MP0004264_abnormal_extraembryonic_tissu | 4.65291126 |
3 | MP0001666_abnormal_nutrient_absorption | 3.91208431 |
4 | MP0005360_urolithiasis | 3.84155431 |
5 | MP0010234_abnormal_vibrissa_follicle | 3.74600182 |
6 | MP0000462_abnormal_digestive_system | 3.48564389 |
7 | MP0003315_abnormal_perineum_morphology | 3.39621205 |
8 | * MP0004957_abnormal_blastocyst_morpholog | 3.25015962 |
9 | MP0005377_hearing/vestibular/ear_phenot | 3.18231924 |
10 | MP0003878_abnormal_ear_physiology | 3.18231924 |
11 | MP0000537_abnormal_urethra_morphology | 3.09459115 |
12 | MP0003866_abnormal_defecation | 3.06435769 |
13 | MP0003183_abnormal_peptide_metabolism | 2.94741591 |
14 | * MP0003693_abnormal_embryo_hatching | 2.94202758 |
15 | MP0000490_abnormal_crypts_of | 2.65291801 |
16 | MP0002796_impaired_skin_barrier | 2.37697375 |
17 | MP0004019_abnormal_vitamin_homeostasis | 2.29624469 |
18 | MP0002822_catalepsy | 2.27337455 |
19 | MP0005409_darkened_coat_color | 2.16402788 |
20 | MP0005085_abnormal_gallbladder_physiolo | 2.08638114 |
21 | MP0000678_abnormal_parathyroid_gland | 2.06168070 |
22 | MP0003705_abnormal_hypodermis_morpholog | 2.03729237 |
23 | * MP0000477_abnormal_intestine_morphology | 1.98887034 |
24 | MP0003941_abnormal_skin_development | 1.98760169 |
25 | MP0003806_abnormal_nucleotide_metabolis | 1.92149051 |
26 | MP0003718_maternal_effect | 1.87065714 |
27 | MP0005381_digestive/alimentary_phenotyp | 1.85232588 |
28 | MP0010155_abnormal_intestine_physiology | 1.80873583 |
29 | * MP0003111_abnormal_nucleus_morphology | 1.80323210 |
30 | MP0001663_abnormal_digestive_system | 1.80322380 |
31 | MP0003283_abnormal_digestive_organ | 1.70908567 |
32 | MP0004858_abnormal_nervous_system | 1.70494622 |
33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.65439808 |
34 | MP0005670_abnormal_white_adipose | 1.63356644 |
35 | MP0001873_stomach_inflammation | 1.63123382 |
36 | MP0003868_abnormal_feces_composition | 1.62854576 |
37 | MP0005166_decreased_susceptibility_to | 1.59271810 |
38 | MP0001730_embryonic_growth_arrest | 1.58055863 |
39 | MP0002876_abnormal_thyroid_physiology | 1.49534418 |
40 | MP0001188_hyperpigmentation | 1.47264174 |
41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46532462 |
42 | MP0010678_abnormal_skin_adnexa | 1.44053386 |
43 | MP0005636_abnormal_mineral_homeostasis | 1.43058951 |
44 | MP0005501_abnormal_skin_physiology | 1.42964623 |
45 | MP0002139_abnormal_hepatobiliary_system | 1.37713614 |
46 | MP0002138_abnormal_hepatobiliary_system | 1.31260486 |
47 | MP0003191_abnormal_cellular_cholesterol | 1.28879541 |
48 | MP0002098_abnormal_vibrissa_morphology | 1.28844850 |
49 | MP0010329_abnormal_lipoprotein_level | 1.28420881 |
50 | MP0009643_abnormal_urine_homeostasis | 1.27555764 |
51 | MP0001756_abnormal_urination | 1.25852444 |
52 | MP0000566_synostosis | 1.22888632 |
53 | MP0010030_abnormal_orbit_morphology | 1.22001196 |
54 | MP0004043_abnormal_pH_regulation | 1.21338628 |
55 | MP0003938_abnormal_ear_development | 1.20415405 |
56 | MP0004782_abnormal_surfactant_physiolog | 1.20250793 |
57 | MP0008260_abnormal_autophagy | 1.17501147 |
58 | MP0006035_abnormal_mitochondrial_morpho | 1.16909895 |
59 | * MP0002086_abnormal_extraembryonic_tissu | 1.16298734 |
60 | MP0001849_ear_inflammation | 1.15631033 |
61 | MP0009053_abnormal_anal_canal | 1.14793677 |
62 | * MP0005380_embryogenesis_phenotype | 1.14740961 |
63 | * MP0001672_abnormal_embryogenesis/_devel | 1.14740961 |
64 | MP0005332_abnormal_amino_acid | 1.10814230 |
65 | MP0001664_abnormal_digestion | 1.07755202 |
66 | MP0001697_abnormal_embryo_size | 1.04348115 |
67 | MP0003252_abnormal_bile_duct | 1.03991946 |
68 | * MP0008932_abnormal_embryonic_tissue | 1.02870648 |
69 | MP0001216_abnormal_epidermal_layer | 1.02698936 |
70 | * MP0002088_abnormal_embryonic_growth/wei | 0.96017866 |
71 | MP0002118_abnormal_lipid_homeostasis | 0.95044259 |
72 | MP0000383_abnormal_hair_follicle | 0.94640884 |
73 | MP0000538_abnormal_urinary_bladder | 0.94530236 |
74 | * MP0003077_abnormal_cell_cycle | 0.93225350 |
75 | * MP0002080_prenatal_lethality | 0.91972652 |
76 | * MP0003984_embryonic_growth_retardation | 0.91900500 |
77 | MP0005058_abnormal_lysosome_morphology | 0.90830565 |
78 | MP0000350_abnormal_cell_proliferation | 0.89576950 |
79 | MP0005451_abnormal_body_composition | 0.88459076 |
80 | MP0002166_altered_tumor_susceptibility | 0.87993263 |
81 | * MP0002085_abnormal_embryonic_tissue | 0.87523964 |
82 | MP0005666_abnormal_adipose_tissue | 0.87300908 |
83 | MP0009333_abnormal_splenocyte_physiolog | 0.86377631 |
84 | MP0003123_paternal_imprinting | 0.85984488 |
85 | MP0009379_abnormal_foot_pigmentation | 0.84975574 |
86 | MP0000465_gastrointestinal_hemorrhage | 0.84860649 |
87 | MP0003303_peritoneal_inflammation | 0.84826395 |
88 | MP0005365_abnormal_bile_salt | 0.84344344 |
89 | MP0005023_abnormal_wound_healing | 0.84186576 |
90 | MP0003221_abnormal_cardiomyocyte_apopto | 0.83614195 |
91 | * MP0010352_gastrointestinal_tract_polyps | 0.82745689 |
92 | MP0001765_abnormal_ion_homeostasis | 0.81324220 |
93 | MP0002089_abnormal_postnatal_growth/wei | 0.79950871 |
94 | MP0000230_abnormal_systemic_arterial | 0.79778242 |
95 | MP0000377_abnormal_hair_follicle | 0.79202762 |
96 | MP0002249_abnormal_larynx_morphology | 0.78982810 |
97 | MP0000762_abnormal_tongue_morphology | 0.78953555 |
98 | MP0001845_abnormal_inflammatory_respons | 0.78455861 |
99 | MP0005319_abnormal_enzyme/_coenzyme | 0.78434620 |
100 | MP0008004_abnormal_stomach_pH | 0.77875992 |
101 | MP0003724_increased_susceptibility_to | 0.77360894 |
102 | MP0003329_amyloid_beta_deposits | 0.75046201 |
103 | MP0002896_abnormal_bone_mineralization | 0.74858252 |
104 | MP0002971_abnormal_brown_adipose | 0.73915943 |
105 | MP0005167_abnormal_blood-brain_barrier | 0.73367945 |
106 | MP0000516_abnormal_urinary_system | 0.73201337 |
107 | MP0005367_renal/urinary_system_phenotyp | 0.73201337 |
108 | MP0002009_preneoplasia | 0.72598304 |
109 | MP0001485_abnormal_pinna_reflex | 0.72488853 |
110 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.72181618 |
111 | MP0009785_altered_susceptibility_to | 0.71509638 |
112 | MP0005448_abnormal_energy_balance | 0.71088581 |
113 | MP0005310_abnormal_salivary_gland | 0.70942057 |
114 | * MP0002084_abnormal_developmental_patter | 0.70111355 |
115 | MP0000681_abnormal_thyroid_gland | 0.69287744 |
116 | MP0005075_abnormal_melanosome_morpholog | 0.69066793 |
117 | MP0008872_abnormal_physiological_respon | 0.68330584 |
118 | MP0004947_skin_inflammation | 0.66592193 |
119 | MP0003879_abnormal_hair_cell | 0.66337646 |
120 | MP0009115_abnormal_fat_cell | 0.65586911 |
121 | MP0000358_abnormal_cell_content/ | 0.64940149 |
122 | MP0000467_abnormal_esophagus_morphology | 0.64697070 |
123 | MP0005395_other_phenotype | 0.64668924 |
124 | MP0003300_gastrointestinal_ulcer | 0.64234397 |
125 | MP0000609_abnormal_liver_physiology | 0.63942645 |
126 | MP0002006_tumorigenesis | 0.63120337 |
127 | MP0005025_abnormal_response_to | 0.63009069 |
128 | MP0004197_abnormal_fetal_growth/weight/ | 0.62066904 |
129 | MP0001881_abnormal_mammary_gland | 0.61150695 |
130 | MP0005266_abnormal_metabolism | 0.60919631 |
131 | MP0002136_abnormal_kidney_physiology | 0.60596590 |
132 | MP0004147_increased_porphyrin_level | 0.60577021 |
133 | * MP0003119_abnormal_digestive_system | 0.60498600 |
134 | MP0003566_abnormal_cell_adhesion | 0.59585436 |
135 | MP0000647_abnormal_sebaceous_gland | 0.58941509 |
136 | MP0003453_abnormal_keratinocyte_physiol | 0.58516931 |
137 | MP0001764_abnormal_homeostasis | 0.57329520 |
138 | MP0009642_abnormal_blood_homeostasis | 0.56229547 |
139 | MP0005187_abnormal_penis_morphology | 0.56042818 |
140 | MP0004185_abnormal_adipocyte_glucose | 0.55616906 |
141 | MP0006082_CNS_inflammation | 0.55340657 |
142 | MP0003950_abnormal_plasma_membrane | 0.54990084 |
143 | MP0000627_abnormal_mammary_gland | 0.54225907 |
144 | MP0003436_decreased_susceptibility_to | 0.53323990 |
145 | * MP0002111_abnormal_tail_morphology | 0.52725585 |
146 | * MP0003937_abnormal_limbs/digits/tail_de | 0.52696587 |
147 | MP0004270_analgesia | 0.52189883 |
148 | MP0000604_amyloidosis | 0.51981743 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ileus (HP:0002595) | 8.58446213 |
2 | Decreased circulating renin level (HP:0003351) | 5.29461107 |
3 | Abnormality of proline metabolism (HP:0010907) | 5.03061887 |
4 | Hydroxyprolinuria (HP:0003080) | 5.03061887 |
5 | Abnormality of renin-angiotensin system (HP:0000847) | 4.68488514 |
6 | Alkalosis (HP:0001948) | 4.25486187 |
7 | Chronic diarrhea (HP:0002028) | 4.14213288 |
8 | Systemic lupus erythematosus (HP:0002725) | 4.09592594 |
9 | Multiple enchondromatosis (HP:0005701) | 4.08954677 |
10 | Septate vagina (HP:0001153) | 4.04023584 |
11 | Malnutrition (HP:0004395) | 4.03948468 |
12 | Right ventricular cardiomyopathy (HP:0011663) | 3.94303888 |
13 | Abdominal distention (HP:0003270) | 3.62785479 |
14 | Gastrointestinal dysmotility (HP:0002579) | 3.62097963 |
15 | Confusion (HP:0001289) | 3.54643613 |
16 | Congenital sensorineural hearing impairment (HP:0008527) | 3.42869530 |
17 | Myopathic facies (HP:0002058) | 3.37506842 |
18 | Abnormality of the 1st metacarpal (HP:0010009) | 3.35144129 |
19 | Micronodular cirrhosis (HP:0001413) | 3.26545879 |
20 | Cheilitis (HP:0100825) | 3.26501118 |
21 | Hemorrhage of the eye (HP:0011885) | 3.23921399 |
22 | Breast hypoplasia (HP:0003187) | 3.22533586 |
23 | Ventricular fibrillation (HP:0001663) | 3.15212855 |
24 | Villous atrophy (HP:0011473) | 3.11972362 |
25 | Abnormality of small intestinal villus morphology (HP:0011472) | 3.11972362 |
26 | Trismus (HP:0000211) | 3.06438614 |
27 | Hyperparathyroidism (HP:0000843) | 2.96941550 |
28 | Wide cranial sutures (HP:0010537) | 2.90987521 |
29 | Thin bony cortex (HP:0002753) | 2.88149731 |
30 | Abnormal cartilage morphology (HP:0002763) | 2.83824045 |
31 | Microretrognathia (HP:0000308) | 2.82569989 |
32 | Pustule (HP:0200039) | 2.81632824 |
33 | Nausea (HP:0002018) | 2.76965335 |
34 | Megaloblastic anemia (HP:0001889) | 2.76443509 |
35 | Pili torti (HP:0003777) | 2.72243292 |
36 | Macrocytic anemia (HP:0001972) | 2.71881084 |
37 | Hyperaldosteronism (HP:0000859) | 2.68040931 |
38 | Tongue fasciculations (HP:0001308) | 2.61858881 |
39 | Bundle branch block (HP:0011710) | 2.60296273 |
40 | Nephrolithiasis (HP:0000787) | 2.56357259 |
41 | Proximal tubulopathy (HP:0000114) | 2.56272942 |
42 | Polycythemia (HP:0001901) | 2.56191330 |
43 | Metabolic alkalosis (HP:0200114) | 2.54659662 |
44 | Hypokalemia (HP:0002900) | 2.54143256 |
45 | Hypobetalipoproteinemia (HP:0003563) | 2.53978420 |
46 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.49948024 |
47 | Eczematoid dermatitis (HP:0000976) | 2.48579725 |
48 | Increased purine levels (HP:0004368) | 2.48255222 |
49 | Hyperuricemia (HP:0002149) | 2.48255222 |
50 | Abnormal hair laboratory examination (HP:0003328) | 2.48072353 |
51 | Intrahepatic cholestasis (HP:0001406) | 2.47830592 |
52 | Abnormality of glycolipid metabolism (HP:0010969) | 2.46431741 |
53 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.46431741 |
54 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.46431741 |
55 | Posterior subcapsular cataract (HP:0007787) | 2.46043555 |
56 | Hyperactive renin-angiotensin system (HP:0000841) | 2.45436953 |
57 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.45062665 |
58 | Atrioventricular block (HP:0001678) | 2.42632759 |
59 | Pigmentary retinal degeneration (HP:0001146) | 2.41923795 |
60 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.41272536 |
61 | Renal tubular acidosis (HP:0001947) | 2.40758272 |
62 | Hyperglycinuria (HP:0003108) | 2.40300064 |
63 | Hypotension (HP:0002615) | 2.38685088 |
64 | Muscle fibrillation (HP:0010546) | 2.38404758 |
65 | Prolonged neonatal jaundice (HP:0006579) | 2.36891470 |
66 | Abnormal biliary tract morphology (HP:0012440) | 2.36086503 |
67 | Hyponatremia (HP:0002902) | 2.32610130 |
68 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.31874734 |
69 | Abnormality of glycine metabolism (HP:0010895) | 2.31874734 |
70 | Reticulocytopenia (HP:0001896) | 2.31430038 |
71 | Alopecia of scalp (HP:0002293) | 2.28542848 |
72 | Breech presentation (HP:0001623) | 2.27886394 |
73 | Esophageal varix (HP:0002040) | 2.27308238 |
74 | Abnormality of complement system (HP:0005339) | 2.25363881 |
75 | Flat acetabular roof (HP:0003180) | 2.25245215 |
76 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.24397464 |
77 | Rough bone trabeculation (HP:0100670) | 2.23123045 |
78 | Abnormal tarsal ossification (HP:0008369) | 2.22475989 |
79 | Hypolipoproteinemia (HP:0010981) | 2.22110938 |
80 | Cupped ribs (HP:0000887) | 2.21891600 |
81 | Growth hormone excess (HP:0000845) | 2.21776581 |
82 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.21657847 |
83 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.21151422 |
84 | Hypophosphatemia (HP:0002148) | 2.19458905 |
85 | Rectal prolapse (HP:0002035) | 2.19250303 |
86 | Glomerulonephritis (HP:0000099) | 2.18358894 |
87 | Spastic paraparesis (HP:0002313) | 2.18089447 |
88 | Short phalanx of the thumb (HP:0009660) | 2.17855557 |
89 | Delayed epiphyseal ossification (HP:0002663) | 2.17327643 |
90 | Gout (HP:0001997) | 2.17226909 |
91 | Abnormality of magnesium homeostasis (HP:0004921) | 2.16913275 |
92 | Hyperphosphatemia (HP:0002905) | 2.16664037 |
93 | Biliary tract neoplasm (HP:0100574) | 2.16544175 |
94 | Athetosis (HP:0002305) | 2.15038791 |
95 | Abnormality of potassium homeostasis (HP:0011042) | 2.14864135 |
96 | Conjugated hyperbilirubinemia (HP:0002908) | 2.14476910 |
97 | Carpal bone hypoplasia (HP:0001498) | 2.14295346 |
98 | Abnormality of chloride homeostasis (HP:0011422) | 2.14223891 |
99 | Heart block (HP:0012722) | 2.13996692 |
100 | Poor head control (HP:0002421) | 2.11499713 |
101 | Abnormal atrioventricular conduction (HP:0005150) | 2.10731774 |
102 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.09205114 |
103 | Abnormality of the umbilical cord (HP:0010881) | 2.08365101 |
104 | Concave nail (HP:0001598) | 2.08070292 |
105 | Cerebral hypomyelination (HP:0006808) | 2.08060376 |
106 | Late onset (HP:0003584) | 2.06720120 |
107 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 2.05493884 |
108 | Short 1st metacarpal (HP:0010034) | 2.04450184 |
109 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.04450184 |
110 | Steatorrhea (HP:0002570) | 2.04121898 |
111 | Cerebral palsy (HP:0100021) | 2.03965710 |
112 | Abnormality of nucleobase metabolism (HP:0010932) | 2.03496835 |
113 | Uterine neoplasm (HP:0010784) | 2.02680151 |
114 | Subcapsular cataract (HP:0000523) | 2.01982611 |
115 | Male infertility (HP:0003251) | 2.01651227 |
116 | Abnormality of purine metabolism (HP:0004352) | 2.00880540 |
117 | Abnormality of vitamin B metabolism (HP:0004340) | 2.00091841 |
118 | Complement deficiency (HP:0004431) | 1.99767887 |
119 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.98629035 |
120 | Flattened epiphyses (HP:0003071) | 1.97395160 |
121 | Secondary amenorrhea (HP:0000869) | 1.96738265 |
122 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.95964152 |
123 | Dicarboxylic aciduria (HP:0003215) | 1.95964152 |
124 | Symptomatic seizures (HP:0011145) | 1.95652533 |
125 | Abnormality of vitamin metabolism (HP:0100508) | 1.94986614 |
126 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.93871836 |
127 | Pancreatitis (HP:0001733) | 1.93456452 |
128 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.93198870 |
129 | Dehydration (HP:0001944) | 1.93076711 |
130 | Double outlet right ventricle (HP:0001719) | 1.91510984 |
131 | Congenital malformation of the right heart (HP:0011723) | 1.91510984 |
132 | Petechiae (HP:0000967) | 1.91277743 |
133 | Short humerus (HP:0005792) | 1.91080265 |
134 | Syncope (HP:0001279) | 1.90673699 |
135 | Protuberant abdomen (HP:0001538) | 1.90211858 |
136 | Hyperammonemia (HP:0001987) | 1.89845629 |
137 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.89470002 |
138 | Acanthocytosis (HP:0001927) | 1.89067833 |
139 | Nephritis (HP:0000123) | 1.87512324 |
140 | Sparse eyelashes (HP:0000653) | 1.87380290 |
141 | Glycosuria (HP:0003076) | 1.87120456 |
142 | Abnormality of urine glucose concentration (HP:0011016) | 1.87120456 |
143 | Metabolic acidosis (HP:0001942) | 1.86580171 |
144 | Gastrointestinal carcinoma (HP:0002672) | 1.86458572 |
145 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.86458572 |
146 | Multiple lipomas (HP:0001012) | 1.86342275 |
147 | Potter facies (HP:0002009) | 1.86269276 |
148 | Facial shape deformation (HP:0011334) | 1.86269276 |
149 | Abnormal number of erythroid precursors (HP:0012131) | 1.85738025 |
150 | Abnormality of carpal bone ossification (HP:0006257) | 1.85619114 |
151 | Visceral angiomatosis (HP:0100761) | 1.85525968 |
152 | Xanthomatosis (HP:0000991) | 1.84701398 |
153 | Curly hair (HP:0002212) | 1.84310590 |
154 | Fat malabsorption (HP:0002630) | 1.83371321 |
155 | Fragile nails (HP:0001808) | 1.81437401 |
156 | Widely patent fontanelles and sutures (HP:0004492) | 1.80788269 |
157 | Premature ovarian failure (HP:0008209) | 1.79243209 |
158 | Absent radius (HP:0003974) | 1.77675186 |
159 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.76310945 |
160 | Palpitations (HP:0001962) | 1.75847343 |
161 | Focal segmental glomerulosclerosis (HP:0000097) | 1.75324561 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 8.82864118 |
2 | ACVR1B | 5.82685702 |
3 | BUB1 | 4.13265454 |
4 | ERN1 | 3.68614376 |
5 | WEE1 | 3.13333586 |
6 | MAP2K2 | 2.92983403 |
7 | NME1 | 2.83991187 |
8 | STK39 | 2.78566471 |
9 | TTK | 2.78193348 |
10 | PIK3CA | 2.73393353 |
11 | MST4 | 2.59761186 |
12 | GRK6 | 2.55640238 |
13 | LMTK2 | 2.50864104 |
14 | AKT3 | 2.29302307 |
15 | OXSR1 | 2.06308947 |
16 | RPS6KB2 | 2.03018235 |
17 | PRKG2 | 1.98060113 |
18 | MST1R | 1.93909358 |
19 | FGFR4 | 1.92452239 |
20 | FRK | 1.74519224 |
21 | IRAK3 | 1.71827486 |
22 | MAP3K8 | 1.67887401 |
23 | PRKCI | 1.66984905 |
24 | PLK4 | 1.66946192 |
25 | PAK4 | 1.59356472 |
26 | SMG1 | 1.56291431 |
27 | PRPF4B | 1.47413555 |
28 | STK24 | 1.45445463 |
29 | TSSK6 | 1.43989195 |
30 | PNCK | 1.39681771 |
31 | TESK2 | 1.36090563 |
32 | TAOK1 | 1.34128853 |
33 | NEK1 | 1.31781411 |
34 | TESK1 | 1.27573868 |
35 | NEK2 | 1.20477416 |
36 | MAP3K11 | 1.20117440 |
37 | STK16 | 1.18095638 |
38 | MAP3K1 | 1.16480885 |
39 | EPHB2 | 1.13984668 |
40 | WNK4 | 1.11920214 |
41 | ZAK | 1.10737398 |
42 | MAP3K12 | 1.10181550 |
43 | AURKB | 1.09363407 |
44 | TYK2 | 1.08162838 |
45 | MAP3K2 | 1.01747841 |
46 | MAP4K1 | 1.01652119 |
47 | ABL2 | 1.01632399 |
48 | PLK1 | 0.96966187 |
49 | BRAF | 0.95270144 |
50 | ARAF | 0.94499955 |
51 | SCYL2 | 0.89299982 |
52 | TNIK | 0.88443679 |
53 | EEF2K | 0.88102720 |
54 | PIM2 | 0.87568794 |
55 | PAK1 | 0.87457367 |
56 | EIF2AK1 | 0.82738299 |
57 | KDR | 0.82590508 |
58 | CDC42BPA | 0.81763976 |
59 | MET | 0.80853181 |
60 | EPHB1 | 0.80806088 |
61 | MAP2K1 | 0.80227113 |
62 | STK10 | 0.76944755 |
63 | MAP2K6 | 0.76197976 |
64 | CHEK2 | 0.74918690 |
65 | NME2 | 0.74716493 |
66 | MAP3K3 | 0.74351927 |
67 | MYLK | 0.74117194 |
68 | EPHA3 | 0.71911706 |
69 | CAMK2G | 0.71347590 |
70 | RIPK4 | 0.69354440 |
71 | CAMK2B | 0.68039660 |
72 | FGFR3 | 0.68035632 |
73 | STK38L | 0.67617109 |
74 | TBK1 | 0.67379234 |
75 | AURKA | 0.66009888 |
76 | ALK | 0.65730156 |
77 | CAMK2D | 0.64837100 |
78 | MARK1 | 0.64691390 |
79 | PRKAA2 | 0.63445705 |
80 | CDK7 | 0.61823627 |
81 | BRSK2 | 0.60476674 |
82 | PDPK1 | 0.60201194 |
83 | PTK2 | 0.58926734 |
84 | ERBB2 | 0.58580223 |
85 | PDK2 | 0.58190668 |
86 | SRPK1 | 0.57488958 |
87 | MAP3K10 | 0.55783194 |
88 | KSR2 | 0.52133890 |
89 | RIPK1 | 0.51595667 |
90 | PTK6 | 0.50572504 |
91 | MATK | 0.50521049 |
92 | DYRK1B | 0.49846435 |
93 | CDK19 | 0.49514888 |
94 | CDK4 | 0.47724226 |
95 | EPHA4 | 0.47543076 |
96 | ICK | 0.47434306 |
97 | FER | 0.46868464 |
98 | CDK12 | 0.46633031 |
99 | PDK3 | 0.44667271 |
100 | PDK4 | 0.44667271 |
101 | GRK1 | 0.43568425 |
102 | PRKACG | 0.42516877 |
103 | DDR2 | 0.42256450 |
104 | CSNK1E | 0.42089986 |
105 | LRRK2 | 0.39921140 |
106 | NLK | 0.39629449 |
107 | DAPK3 | 0.39481811 |
108 | SRC | 0.38170470 |
109 | DYRK3 | 0.36993939 |
110 | BMX | 0.34671300 |
111 | DMPK | 0.33322618 |
112 | TRIB3 | 0.33208278 |
113 | TAOK2 | 0.31835730 |
114 | AKT2 | 0.31694784 |
115 | PLK3 | 0.31589161 |
116 | TAOK3 | 0.29292866 |
117 | IRAK1 | 0.29281705 |
118 | PRKCZ | 0.29174282 |
119 | PRKCA | 0.28533672 |
120 | CHEK1 | 0.27593320 |
121 | CSNK1A1 | 0.27122685 |
122 | PDGFRA | 0.27118280 |
123 | PBK | 0.26578581 |
124 | CSNK2A1 | 0.26265801 |
125 | RET | 0.26257950 |
126 | CDK6 | 0.25863043 |
127 | * CDK2 | 0.24352867 |
128 | CSK | 0.24332886 |
129 | ZAP70 | 0.24189045 |
130 | PRKCD | 0.23049706 |
131 | PDK1 | 0.23034946 |
132 | MAPKAPK2 | 0.21994704 |
133 | IRAK2 | 0.21553273 |
134 | CAMKK2 | 0.20572617 |
135 | STK3 | 0.19381995 |
136 | YES1 | 0.18814073 |
137 | IKBKE | 0.18551121 |
138 | FYN | 0.18435827 |
139 | PIM1 | 0.18419122 |
140 | MAPK11 | 0.18071705 |
141 | RPS6KC1 | 0.17880906 |
142 | RPS6KL1 | 0.17880906 |
143 | RPS6KA2 | 0.16686855 |
144 | LIMK1 | 0.16251811 |
145 | MELK | 0.16055196 |
146 | MAP3K14 | 0.14249716 |
147 | SIK1 | 0.14241188 |
148 | JAK2 | 0.13591255 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 4.32987872 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 3.40553031 |
3 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 3.33650411 |
4 | Mineral absorption_Homo sapiens_hsa04978 | 3.17039220 |
5 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.91049631 |
6 | Proteasome_Homo sapiens_hsa03050 | 2.84676252 |
7 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.76449445 |
8 | Galactose metabolism_Homo sapiens_hsa00052 | 2.63360946 |
9 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.59140669 |
10 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.58406650 |
11 | Ribosome_Homo sapiens_hsa03010 | 2.48828190 |
12 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 2.42995541 |
13 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.23454442 |
14 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.22933108 |
15 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.17710462 |
16 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.02948054 |
17 | Histidine metabolism_Homo sapiens_hsa00340 | 1.76224909 |
18 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.70863547 |
19 | DNA replication_Homo sapiens_hsa03030 | 1.61909745 |
20 | Tight junction_Homo sapiens_hsa04530 | 1.61906936 |
21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.49992400 |
22 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.38620035 |
23 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.34540138 |
24 | RNA polymerase_Homo sapiens_hsa03020 | 1.31115494 |
25 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.28924272 |
26 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.26330361 |
27 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.25876118 |
28 | Carbon metabolism_Homo sapiens_hsa01200 | 1.23301098 |
29 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.21540018 |
30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.18057104 |
31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.17907937 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.17806171 |
33 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.16382209 |
34 | Asthma_Homo sapiens_hsa05310 | 1.10685430 |
35 | Bile secretion_Homo sapiens_hsa04976 | 1.09275744 |
36 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.09018844 |
37 | RNA transport_Homo sapiens_hsa03013 | 1.07904676 |
38 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.05961015 |
39 | Homologous recombination_Homo sapiens_hsa03440 | 1.05476134 |
40 | Mismatch repair_Homo sapiens_hsa03430 | 1.05234928 |
41 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.04339612 |
42 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.02036117 |
43 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.00973172 |
44 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.00162959 |
45 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.99537744 |
46 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.97803265 |
47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.94256487 |
48 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.93782303 |
49 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.91318076 |
50 | Spliceosome_Homo sapiens_hsa03040 | 0.91142274 |
51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.90801220 |
52 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.90677724 |
53 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90518019 |
54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.87951618 |
55 | Parkinsons disease_Homo sapiens_hsa05012 | 0.86313187 |
56 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81754032 |
57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79632649 |
58 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.79427101 |
59 | Huntingtons disease_Homo sapiens_hsa05016 | 0.79020990 |
60 | Allograft rejection_Homo sapiens_hsa05330 | 0.78011847 |
61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76716615 |
62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76541042 |
63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72974869 |
64 | Base excision repair_Homo sapiens_hsa03410 | 0.72128571 |
65 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71745925 |
66 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.71361039 |
67 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.71137878 |
68 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.71054323 |
69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.70109429 |
70 | Thyroid cancer_Homo sapiens_hsa05216 | 0.69431164 |
71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68973595 |
72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.68198640 |
73 | Purine metabolism_Homo sapiens_hsa00230 | 0.67604018 |
74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.67159714 |
75 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.65371541 |
76 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.64924712 |
77 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.64321211 |
78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.63232657 |
79 | Sulfur relay system_Homo sapiens_hsa04122 | 0.63186048 |
80 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.60769369 |
81 | Alzheimers disease_Homo sapiens_hsa05010 | 0.60614567 |
82 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60333090 |
83 | Cell cycle_Homo sapiens_hsa04110 | 0.58025046 |
84 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.57727218 |
85 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.56173587 |
86 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.55790028 |
87 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55673963 |
88 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53708373 |
89 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51521115 |
90 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51058295 |
91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50410862 |
92 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.48374086 |
93 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.47979906 |
94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.45757860 |
95 | Peroxisome_Homo sapiens_hsa04146 | 0.45284473 |
96 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45009116 |
97 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.43433631 |
98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42934701 |
99 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.41356040 |
100 | Adherens junction_Homo sapiens_hsa04520 | 0.41022304 |
101 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.40185499 |
102 | Bladder cancer_Homo sapiens_hsa05219 | 0.38951411 |
103 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38709063 |
104 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.38651749 |
105 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37522885 |
106 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34505555 |
107 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.34240456 |
108 | Other glycan degradation_Homo sapiens_hsa00511 | 0.33972517 |
109 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.33570253 |
110 | Salmonella infection_Homo sapiens_hsa05132 | 0.33278031 |
111 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.33106519 |
112 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32454073 |
113 | Hepatitis C_Homo sapiens_hsa05160 | 0.29294499 |
114 | Leishmaniasis_Homo sapiens_hsa05140 | 0.28381837 |
115 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.27238982 |
116 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.27184401 |
117 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.26420801 |
118 | Insulin resistance_Homo sapiens_hsa04931 | 0.25955820 |
119 | Pertussis_Homo sapiens_hsa05133 | 0.25512727 |
120 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.24112685 |
121 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.23576925 |
122 | Renin secretion_Homo sapiens_hsa04924 | 0.23133376 |
123 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.20941067 |
124 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.20320256 |
125 | Viral myocarditis_Homo sapiens_hsa05416 | 0.15921071 |
126 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.15204869 |
127 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.12414454 |
128 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.12252860 |
129 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.11466414 |
130 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.08622801 |
131 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.06974582 |
132 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.06622755 |
133 | Influenza A_Homo sapiens_hsa05164 | 0.03284111 |
134 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.03148205 |
135 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.01619534 |
136 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.00960035 |
137 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.00895122 |
138 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.00178051 |