CDY4P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1auditory receptor cell differentiation (GO:0042491)6.66576857
2positive regulation of actin filament depolymerization (GO:0030836)5.44578896
3regulation of nuclear cell cycle DNA replication (GO:0033262)5.42375822
4mitochondrial DNA replication (GO:0006264)5.30701880
5positive regulation of prostaglandin secretion (GO:0032308)4.85949386
6mitochondrial DNA metabolic process (GO:0032042)4.59676602
7regulation of cytokine secretion involved in immune response (GO:0002739)4.40281718
8S-adenosylmethionine metabolic process (GO:0046500)4.37041014
9glycerophospholipid catabolic process (GO:0046475)4.11313817
10regulation of prostaglandin secretion (GO:0032306)4.10932813
11positive regulation of natural killer cell differentiation (GO:0032825)4.09969827
12seminiferous tubule development (GO:0072520)3.98134422
13regulation of Rac protein signal transduction (GO:0035020)3.74952232
14mitochondrial fragmentation involved in apoptotic process (GO:0043653)3.71764355
15L-phenylalanine catabolic process (GO:0006559)3.69337360
16erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.69337360
17lateral ventricle development (GO:0021670)3.66396463
18leukotriene biosynthetic process (GO:0019370)3.58512609
19negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.58361502
20positive regulation of histone H3-K4 methylation (GO:0051571)3.58301203
21positive regulation of DNA-dependent DNA replication (GO:2000105)3.55313406
22sequestering of extracellular ligand from receptor (GO:0035581)3.44446067
23lactate metabolic process (GO:0006089)3.41338192
24toxin transport (GO:1901998)3.37637675
25positive regulation of digestive system process (GO:0060456)3.37136947
26hair cell differentiation (GO:0035315)3.35992940
27positive regulation of uterine smooth muscle contraction (GO:0070474)3.30158723
28cilium morphogenesis (GO:0060271)3.28603009
29positive regulation of macroautophagy (GO:0016239)3.26346455
30macroautophagy (GO:0016236)3.25147267
31regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.22842308
32epithelial cilium movement (GO:0003351)3.16110670
33protein localization to cilium (GO:0061512)3.14895835
34regulation of gonadotropin secretion (GO:0032276)3.07935493
35inner ear receptor cell differentiation (GO:0060113)3.06662520
36protein K11-linked deubiquitination (GO:0035871)3.04213911
37cytochrome complex assembly (GO:0017004)3.02766150
38regulation of sarcomere organization (GO:0060297)3.01818417
39interferon-gamma secretion (GO:0072643)3.01776490
40magnesium ion transport (GO:0015693)3.00705788
41peroxisome fission (GO:0016559)2.99706093
42C-terminal protein lipidation (GO:0006501)2.99599768
43base-excision repair, AP site formation (GO:0006285)2.98971781
44cochlea development (GO:0090102)2.98859017
45platelet dense granule organization (GO:0060155)2.98444342
46regulation of DNA endoreduplication (GO:0032875)2.96838057
47C-terminal protein amino acid modification (GO:0018410)2.96657113
48preassembly of GPI anchor in ER membrane (GO:0016254)2.96589280
49L-fucose catabolic process (GO:0042355)2.94406542
50fucose catabolic process (GO:0019317)2.94406542
51L-fucose metabolic process (GO:0042354)2.94406542
52pyrimidine nucleotide catabolic process (GO:0006244)2.93925352
53aromatic amino acid family catabolic process (GO:0009074)2.93075782
54kynurenine metabolic process (GO:0070189)2.88799373
55RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.88794809
56cell differentiation involved in metanephros development (GO:0072202)2.87334420
57positive regulation of protein depolymerization (GO:1901881)2.86070779
58regulation of fibrinolysis (GO:0051917)2.84697956
59positive regulation of icosanoid secretion (GO:0032305)2.82902144
60positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.79169869
61branched-chain amino acid catabolic process (GO:0009083)2.78305131
62insulin secretion (GO:0030073)2.77529927
63regulation of chromatin silencing (GO:0031935)2.77108474
64positive regulation of cardiac muscle cell proliferation (GO:0060045)2.76692241
65erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.76060907
66L-phenylalanine metabolic process (GO:0006558)2.76060907
67estrogen biosynthetic process (GO:0006703)2.74241980
68cellular ketone body metabolic process (GO:0046950)2.73835714
69positive regulation of catecholamine secretion (GO:0033605)2.72561421
70positive regulation of histone methylation (GO:0031062)2.71792616
71GMP metabolic process (GO:0046037)2.71743058
72cellular response to nicotine (GO:0071316)2.71694441
73inner ear receptor cell development (GO:0060119)2.71490267
74respiratory chain complex IV assembly (GO:0008535)2.70094583
75regulation of natural killer cell differentiation (GO:0032823)2.69316640
76dopamine transport (GO:0015872)2.69078033
77regulation of glucokinase activity (GO:0033131)2.68707002
78regulation of hexokinase activity (GO:1903299)2.68707002
79hepatocyte differentiation (GO:0070365)2.66751278
80positive regulation of fatty acid transport (GO:2000193)2.66615566
81tyrosine metabolic process (GO:0006570)2.66385401
82cardiolipin metabolic process (GO:0032048)2.65816176
83fucose metabolic process (GO:0006004)2.65616873
84negative regulation of cytosolic calcium ion concentration (GO:0051481)2.64921838
85negative regulation of JUN kinase activity (GO:0043508)2.63662513
86regulation of interleukin-8 secretion (GO:2000482)2.62522502
87phospholipid homeostasis (GO:0055091)2.61456728
88regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.61102870
89positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.61102870
90female gonad development (GO:0008585)2.59878581
91cytoplasmic mRNA processing body assembly (GO:0033962)2.58777442
92amine catabolic process (GO:0009310)2.58626618
93cellular biogenic amine catabolic process (GO:0042402)2.58626618
94parturition (GO:0007567)2.58486909
95rRNA methylation (GO:0031167)2.58153474
96positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.57873427
97pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.57675202
98valine metabolic process (GO:0006573)2.57013780
99cilium movement (GO:0003341)2.56892069
100embryonic body morphogenesis (GO:0010172)2.56388850

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IGF1R_20145208_ChIP-Seq_DFB_Human5.33262570
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.96192162
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.60284657
4FLI1_27457419_Chip-Seq_LIVER_Mouse2.73118270
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.71928091
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.71444509
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.51585466
8TAF15_26573619_Chip-Seq_HEK293_Human2.47690356
9ZNF274_21170338_ChIP-Seq_K562_Hela2.47337875
10VDR_22108803_ChIP-Seq_LS180_Human2.46039591
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.44237588
12FUS_26573619_Chip-Seq_HEK293_Human2.21442923
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.08348040
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.06125891
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.05373554
16GBX2_23144817_ChIP-Seq_PC3_Human1.97405894
17P300_19829295_ChIP-Seq_ESCs_Human1.92746483
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.86456543
19EWS_26573619_Chip-Seq_HEK293_Human1.85620881
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.77116619
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.73568931
22HTT_18923047_ChIP-ChIP_STHdh_Human1.67401164
23EZH2_27294783_Chip-Seq_NPCs_Mouse1.65723373
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61830645
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60257739
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.59356134
27SMAD4_21799915_ChIP-Seq_A2780_Human1.57910476
28TP53_22573176_ChIP-Seq_HFKS_Human1.56081477
29SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53432233
30SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.53029745
31NFE2_27457419_Chip-Seq_LIVER_Mouse1.52962927
32MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.52962567
33NANOG_19829295_ChIP-Seq_ESCs_Human1.51995095
34SOX2_19829295_ChIP-Seq_ESCs_Human1.51995095
35SMAD3_21741376_ChIP-Seq_EPCs_Human1.51594373
36BCAT_22108803_ChIP-Seq_LS180_Human1.51356780
37ELK1_19687146_ChIP-ChIP_HELA_Human1.50632389
38NANOG_18555785_Chip-Seq_ESCs_Mouse1.49776008
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.49118015
40EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.48035464
41SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47870266
42STAT3_23295773_ChIP-Seq_U87_Human1.47327423
43CDX2_22108803_ChIP-Seq_LS180_Human1.46259288
44TP53_16413492_ChIP-PET_HCT116_Human1.45385753
45AR_25329375_ChIP-Seq_VCAP_Human1.44655995
46TCF4_23295773_ChIP-Seq_U87_Human1.43955416
47RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.43082014
48EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.42640726
49TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41919005
50MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.40183979
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39890533
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.39499578
53EGR1_23403033_ChIP-Seq_LIVER_Mouse1.38019476
54P53_22387025_ChIP-Seq_ESCs_Mouse1.36832824
55ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.35579740
56IRF1_19129219_ChIP-ChIP_H3396_Human1.34600819
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.33848958
58CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.33652168
59ER_23166858_ChIP-Seq_MCF-7_Human1.33152826
60RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32870469
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31996775
62E2F1_18555785_Chip-Seq_ESCs_Mouse1.31622390
63CTCF_18555785_Chip-Seq_ESCs_Mouse1.29960846
64STAT3_18555785_Chip-Seq_ESCs_Mouse1.29330687
65P300_18555785_Chip-Seq_ESCs_Mouse1.28564804
66SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.28148462
67CRX_20693478_ChIP-Seq_RETINA_Mouse1.26146660
68CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25394797
69FLI1_21867929_ChIP-Seq_TH2_Mouse1.24732847
70VDR_23849224_ChIP-Seq_CD4+_Human1.23123616
71CMYC_18555785_Chip-Seq_ESCs_Mouse1.22156375
72SUZ12_18555785_Chip-Seq_ESCs_Mouse1.21550435
73UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21501824
74SOX2_18555785_Chip-Seq_ESCs_Mouse1.20122477
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19164767
76CBP_20019798_ChIP-Seq_JUKART_Human1.19164767
77HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.17450996
78AR_20517297_ChIP-Seq_VCAP_Human1.16911739
79EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.15139672
80PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14524833
81OCT4_18555785_Chip-Seq_ESCs_Mouse1.14124649
82ESR1_15608294_ChIP-ChIP_MCF-7_Human1.13839106
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13723937
84TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13723937
85NMYC_18555785_Chip-Seq_ESCs_Mouse1.13078323
86TCF4_22108803_ChIP-Seq_LS180_Human1.12687190
87BRD4_25478319_ChIP-Seq_HGPS_Human1.12128681
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11406845
89FOXM1_26456572_ChIP-Seq_MCF-7_Human1.10883537
90FOXA1_21572438_ChIP-Seq_LNCaP_Human1.10472150
91TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09773665
92KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.09519653
93NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07500093
94ZFX_18555785_Chip-Seq_ESCs_Mouse1.06141220
95ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05394760
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.02359457
97OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01538633
98KLF4_18555785_Chip-Seq_ESCs_Mouse1.00554281
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00226395
100SMAD4_21741376_ChIP-Seq_EPCs_Human1.00126825

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation4.22856893
2MP0002163_abnormal_gland_morphology3.04241752
3MP0005645_abnormal_hypothalamus_physiol2.99636050
4MP0002653_abnormal_ependyma_morphology2.88875789
5MP0005174_abnormal_tail_pigmentation2.75719218
6MP0008995_early_reproductive_senescence2.74340867
7MP0002837_dystrophic_cardiac_calcinosis2.73074761
8MP0005379_endocrine/exocrine_gland_phen2.59061887
9MP0008057_abnormal_DNA_replication2.51034954
10MP0002938_white_spotting2.47979873
11MP0009697_abnormal_copulation2.42619116
12MP0000613_abnormal_salivary_gland2.42076962
13MP0008877_abnormal_DNA_methylation2.31021433
14MP0003890_abnormal_embryonic-extraembry2.29626296
15MP0006054_spinal_hemorrhage2.23703824
16MP0002254_reproductive_system_inflammat2.23526421
17MP0005084_abnormal_gallbladder_morpholo2.06163384
18MP0002822_catalepsy1.98040328
19MP0002909_abnormal_adrenal_gland1.91348498
20MP0005220_abnormal_exocrine_pancreas1.89028463
21MP0003195_calcinosis1.87659817
22MP0010386_abnormal_urinary_bladder1.82799565
23MP0000427_abnormal_hair_cycle1.82515105
24MP0003122_maternal_imprinting1.76078498
25MP0001984_abnormal_olfaction1.75514591
26MP0001986_abnormal_taste_sensitivity1.74998123
27MP0002006_tumorigenesis1.71694417
28MP0003787_abnormal_imprinting1.71223408
29MP0002009_preneoplasia1.68241906
30MP0001502_abnormal_circadian_rhythm1.65849811
31MP0004133_heterotaxia1.63421225
32MP0005365_abnormal_bile_salt1.63285958
33MP0005187_abnormal_penis_morphology1.58741932
34MP0002638_abnormal_pupillary_reflex1.57911825
35MP0010329_abnormal_lipoprotein_level1.48131481
36MP0004043_abnormal_pH_regulation1.48118266
37MP0005085_abnormal_gallbladder_physiolo1.46679889
38MP0005551_abnormal_eye_electrophysiolog1.44941211
39MP0003191_abnormal_cellular_cholesterol1.37317093
40MP0003786_premature_aging1.36228889
41MP0000383_abnormal_hair_follicle1.35423474
42MP0001501_abnormal_sleep_pattern1.34464259
43MP0003943_abnormal_hepatobiliary_system1.31488018
44MP0001944_abnormal_pancreas_morphology1.31059953
45MP0005332_abnormal_amino_acid1.30194705
46MP0001764_abnormal_homeostasis1.28382909
47MP0003121_genomic_imprinting1.26896896
48MP0006072_abnormal_retinal_apoptosis1.26885139
49MP0002693_abnormal_pancreas_physiology1.26453049
50MP0005330_cardiomyopathy1.25539084
51MP0002751_abnormal_autonomic_nervous1.17401582
52MP0008872_abnormal_physiological_respon1.16289470
53MP0002095_abnormal_skin_pigmentation1.10728165
54MP0003137_abnormal_impulse_conducting1.09990810
55MP0002876_abnormal_thyroid_physiology1.09714208
56MP0005636_abnormal_mineral_homeostasis1.09362126
57MP0002166_altered_tumor_susceptibility1.09208714
58MP0000569_abnormal_digit_pigmentation1.08324443
59MP0005075_abnormal_melanosome_morpholog1.06777531
60MP0002102_abnormal_ear_morphology1.05521452
61MP0001968_abnormal_touch/_nociception1.04918275
62MP0003718_maternal_effect0.98038914
63MP0000647_abnormal_sebaceous_gland0.96866731
64MP0000371_diluted_coat_color0.95565650
65MP0001765_abnormal_ion_homeostasis0.95414223
66MP0004924_abnormal_behavior0.94933994
67MP0005386_behavior/neurological_phenoty0.94933994
68MP0001970_abnormal_pain_threshold0.93580656
69MP0001756_abnormal_urination0.92635413
70MP0003252_abnormal_bile_duct0.89617210
71MP0001881_abnormal_mammary_gland0.88492060
72MP0000639_abnormal_adrenal_gland0.87452201
73MP0003283_abnormal_digestive_organ0.87220155
74MP0004215_abnormal_myocardial_fiber0.87070034
75MP0003936_abnormal_reproductive_system0.86710596
76MP0002928_abnormal_bile_duct0.84079085
77MP0005167_abnormal_blood-brain_barrier0.83917915
78MP0002078_abnormal_glucose_homeostasis0.83662170
79MP0009745_abnormal_behavioral_response0.83602656
80MP0004085_abnormal_heartbeat0.83352642
81MP0003950_abnormal_plasma_membrane0.82666260
82MP0005310_abnormal_salivary_gland0.82595594
83MP0001119_abnormal_female_reproductive0.82287513
84MP0003136_yellow_coat_color0.81938739
85MP0009046_muscle_twitch0.81622124
86MP0002733_abnormal_thermal_nociception0.80830550
87MP0006276_abnormal_autonomic_nervous0.79372161
88MP0000230_abnormal_systemic_arterial0.79337387
89MP0010368_abnormal_lymphatic_system0.78704557
90MP0003186_abnormal_redox_activity0.78232472
91MP0002272_abnormal_nervous_system0.74561916
92MP0008058_abnormal_DNA_repair0.73744090
93MP0001873_stomach_inflammation0.73232872
94MP0001879_abnormal_lymphatic_vessel0.72344830
95MP0008961_abnormal_basal_metabolism0.70812120
96MP0006035_abnormal_mitochondrial_morpho0.70407456
97MP0000003_abnormal_adipose_tissue0.70233110
98MP0004019_abnormal_vitamin_homeostasis0.69598031
99MP0006036_abnormal_mitochondrial_physio0.64798705
100MP0005248_abnormal_Harderian_gland0.64269915

Predicted human phenotypes

RankGene SetZ-score
1Large for gestational age (HP:0001520)4.83196549
2Pancreatic islet-cell hyperplasia (HP:0004510)4.69017597
3Abnormality of midbrain morphology (HP:0002418)4.39701287
4Molar tooth sign on MRI (HP:0002419)4.39701287
5Progressive inability to walk (HP:0002505)4.01944455
6Pancreatic cysts (HP:0001737)3.89186340
7Pancreatic fibrosis (HP:0100732)3.64801576
8Hypothermia (HP:0002045)3.54003716
9Hyperglycemia (HP:0003074)3.46315816
10Aplasia/Hypoplasia of the tibia (HP:0005772)3.43914248
11Short tibia (HP:0005736)3.41878373
12Ketoacidosis (HP:0001993)3.31419781
13Severe visual impairment (HP:0001141)3.27618162
14Hyperinsulinemic hypoglycemia (HP:0000825)3.22363751
15Prolonged partial thromboplastin time (HP:0003645)3.20420726
16True hermaphroditism (HP:0010459)3.13106703
17Neoplasm of the adrenal gland (HP:0100631)2.96330944
18Bifid tongue (HP:0010297)2.95306059
19Methylmalonic acidemia (HP:0002912)2.95037706
20Abnormality of endocrine pancreas physiology (HP:0012093)2.90772825
21Abnormality of the pancreatic islet cells (HP:0006476)2.90772825
223-Methylglutaconic aciduria (HP:0003535)2.88766212
23Proximal tubulopathy (HP:0000114)2.87565523
24Increased CSF protein (HP:0002922)2.82014648
25Abnormality of alanine metabolism (HP:0010916)2.81763257
26Hyperalaninemia (HP:0003348)2.81763257
27Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.81763257
28Hypoplasia of the fovea (HP:0007750)2.81447253
29Aplasia/Hypoplasia of the fovea (HP:0008060)2.81447253
30Nephronophthisis (HP:0000090)2.81082675
31Intestinal atresia (HP:0011100)2.79164423
32Neurodegeneration (HP:0002180)2.73326541
33Abnormal biliary tract physiology (HP:0012439)2.67161830
34Bile duct proliferation (HP:0001408)2.67161830
35Cystic liver disease (HP:0006706)2.58599231
36Insulin-resistant diabetes mellitus (HP:0000831)2.49795761
37Conjunctival hamartoma (HP:0100780)2.47505053
38Prominent metopic ridge (HP:0005487)2.47004266
39Abnormality of the renal medulla (HP:0100957)2.38093968
40Hemiparesis (HP:0001269)2.34262565
41Abnormality of vitamin B metabolism (HP:0004340)2.33155729
42Congenital stationary night blindness (HP:0007642)2.28309780
43Inability to walk (HP:0002540)2.26262718
44Neuroendocrine neoplasm (HP:0100634)2.25439532
45Abnormality of the metopic suture (HP:0005556)2.24324786
46Chronic hepatic failure (HP:0100626)2.23878853
47Abnormal biliary tract morphology (HP:0012440)2.17156220
48Pheochromocytoma (HP:0002666)2.16907459
49Abnormality of the fovea (HP:0000493)2.16863546
50Nausea (HP:0002018)2.16259441
51Dysautonomia (HP:0002459)2.08556215
52Congenital malformation of the right heart (HP:0011723)2.08053713
53Double outlet right ventricle (HP:0001719)2.08053713
54Tachypnea (HP:0002789)2.07112171
55Albinism (HP:0001022)2.04787667
56Anteriorly placed anus (HP:0001545)2.04632182
57Medial flaring of the eyebrow (HP:0010747)2.03802675
58Concave nail (HP:0001598)2.03676496
59Furrowed tongue (HP:0000221)1.98663606
60Abnormality of B cell number (HP:0010975)1.94555720
61Methylmalonic aciduria (HP:0012120)1.93661901
62Adenoma sebaceum (HP:0009720)1.93088647
63Angiofibromas (HP:0010615)1.93088647
64Palpitations (HP:0001962)1.91368533
65Aplasia/Hypoplasia of the tongue (HP:0010295)1.91325301
66Metaphyseal dysplasia (HP:0100255)1.90180611
67Type I transferrin isoform profile (HP:0003642)1.89616451
68Male pseudohermaphroditism (HP:0000037)1.89209254
69Hamartoma of the eye (HP:0010568)1.89013891
70Abnormality of macular pigmentation (HP:0008002)1.88488120
71Nuclear cataract (HP:0100018)1.88427367
72Neoplasm of the rectum (HP:0100743)1.87647168
73B lymphocytopenia (HP:0010976)1.87174600
74Ketosis (HP:0001946)1.87008409
75Sclerocornea (HP:0000647)1.86358302
76Preaxial hand polydactyly (HP:0001177)1.84685941
77Abnormal delayed hypersensitivity skin test (HP:0002963)1.83344817
78Abnormality of the renal cortex (HP:0011035)1.82820185
79Neoplasm of the adrenal cortex (HP:0100641)1.82139361
80Thyroiditis (HP:0100646)1.80538619
81Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80331628
82Degeneration of the lateral corticospinal tracts (HP:0002314)1.80331628
83Homocystinuria (HP:0002156)1.80139530
84Abnormality of homocysteine metabolism (HP:0010919)1.80139530
85Poor speech (HP:0002465)1.79609663
86Small hand (HP:0200055)1.78688754
87Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.76758259
88Congenital, generalized hypertrichosis (HP:0004540)1.76240896
89Hypomagnesemia (HP:0002917)1.75221785
90Median cleft lip (HP:0000161)1.74485622
91Abnormal pancreas size (HP:0012094)1.73635568
92High pitched voice (HP:0001620)1.71152276
93Failure to thrive in infancy (HP:0001531)1.69538914
94Aplasia/Hypoplasia of the macula (HP:0008059)1.69224381
95Short chin (HP:0000331)1.69146429
96Cerebral palsy (HP:0100021)1.68562361
97Facial diplegia (HP:0001349)1.68495933
98Abnormal protein N-linked glycosylation (HP:0012347)1.68371534
99Abnormal protein glycosylation (HP:0012346)1.68371534
100Abnormal glycosylation (HP:0012345)1.68371534

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB44.51180641
2FRK4.22421699
3PRKD34.00804326
4STK243.22182601
5WNK32.98559522
6PDK22.89130154
7GRK12.87162771
8LATS12.82033209
9BMPR1B2.76403477
10AKT32.41309875
11ADRBK22.24557803
12MAP3K122.19509379
13NUAK12.19028139
14ACVR1B2.16342739
15STK32.08384161
16PTK2B1.98913015
17KIT1.68127557
18TNK21.59569476
19STK38L1.58896477
20DYRK31.46593309
21PAK31.25111146
22TGFBR11.19965884
23MKNK21.19251484
24STK391.19180778
25PRKCE1.16258658
26BCR1.15918314
27PLK21.14765259
28MAP2K71.14031108
29INSRR1.03058701
30ZAK1.00795863
31CAMK2D0.99988680
32TIE10.99325363
33OXSR10.92279240
34CAMK40.89043828
35PIM20.88997979
36FGFR20.88627871
37MAP2K60.88560462
38TAF10.88414386
39TRIM280.87951197
40PDK10.84650245
41MAP3K40.84447981
42CAMK10.81276034
43CASK0.79955359
44MARK30.78761039
45BCKDK0.77940113
46TEC0.77202488
47MAPK130.77011955
48WNK40.76321963
49STK40.72865847
50DAPK20.71646363
51DAPK10.71537220
52MAP2K40.68518045
53MAP3K20.67412489
54TBK10.65576506
55MST40.65344035
56PRKCG0.64832151
57CSNK1G20.64069698
58FER0.64012196
59SGK20.63993395
60NEK90.63900125
61PHKG10.63614600
62PHKG20.63614600
63TAOK30.63282696
64FLT30.62505306
65PRKCI0.62213334
66EIF2AK30.61929543
67TNIK0.60413403
68RPS6KA40.58962381
69ERBB30.58709514
70CSNK1G10.58520235
71PDPK10.58387158
72IKBKE0.57620546
73CSNK1A1L0.56503297
74MAP4K20.55388387
75PRKCH0.52637036
76PLK30.50726339
77ILK0.50484577
78CAMK2A0.50219377
79SYK0.50000584
80NEK20.49573961
81PRKCQ0.48077699
82PRKCZ0.46685966
83PRKG10.43278921
84OBSCN0.41208582
85SIK30.38850001
86TXK0.37677835
87PBK0.36993315
88PKN10.35302281
89SGK2230.32654129
90SGK4940.32654129
91LIMK10.32648680
92MYLK0.32026069
93ATM0.31932906
94EGFR0.31607253
95CSF1R0.31093609
96PRKD20.30596680
97IKBKB0.30186324
98MKNK10.28763808
99MAP3K70.27947807
100CSNK1G30.27821307

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.56408100
2Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.22880397
3Butanoate metabolism_Homo sapiens_hsa006503.13633617
4Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.99310655
5Propanoate metabolism_Homo sapiens_hsa006402.89661040
6RNA polymerase_Homo sapiens_hsa030202.87429958
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.67271949
8Phototransduction_Homo sapiens_hsa047442.51744840
9Insulin secretion_Homo sapiens_hsa049112.41351485
10Circadian rhythm_Homo sapiens_hsa047102.16011748
11SNARE interactions in vesicular transport_Homo sapiens_hsa041301.98166511
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.89120370
13Sulfur metabolism_Homo sapiens_hsa009201.86327320
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.84704628
15Fatty acid elongation_Homo sapiens_hsa000621.81157911
16Protein export_Homo sapiens_hsa030601.77382034
17Oxidative phosphorylation_Homo sapiens_hsa001901.58339563
18Peroxisome_Homo sapiens_hsa041461.52865812
19Fatty acid metabolism_Homo sapiens_hsa012121.52077186
20Nicotine addiction_Homo sapiens_hsa050331.48203272
21Primary bile acid biosynthesis_Homo sapiens_hsa001201.41976664
22Pyrimidine metabolism_Homo sapiens_hsa002401.41839086
23Non-homologous end-joining_Homo sapiens_hsa034501.38710950
24Parkinsons disease_Homo sapiens_hsa050121.38114985
25Mismatch repair_Homo sapiens_hsa034301.35459245
26Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.33411071
27Glutathione metabolism_Homo sapiens_hsa004801.32485522
28Ether lipid metabolism_Homo sapiens_hsa005651.24835201
29Vitamin B6 metabolism_Homo sapiens_hsa007501.15653234
30Nitrogen metabolism_Homo sapiens_hsa009101.13587976
31Linoleic acid metabolism_Homo sapiens_hsa005911.12331459
32Homologous recombination_Homo sapiens_hsa034401.11314595
33Fanconi anemia pathway_Homo sapiens_hsa034601.11246724
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.10589604
35Basal transcription factors_Homo sapiens_hsa030221.08444642
36beta-Alanine metabolism_Homo sapiens_hsa004101.06002060
37Purine metabolism_Homo sapiens_hsa002301.05530717
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05243218
39Steroid hormone biosynthesis_Homo sapiens_hsa001401.02960498
40Tryptophan metabolism_Homo sapiens_hsa003801.01951767
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98014249
42Fatty acid degradation_Homo sapiens_hsa000710.97923933
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97626213
44Pyruvate metabolism_Homo sapiens_hsa006200.95748776
45Intestinal immune network for IgA production_Homo sapiens_hsa046720.93852673
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.91260096
47Type I diabetes mellitus_Homo sapiens_hsa049400.90794064
48Huntingtons disease_Homo sapiens_hsa050160.87143660
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86067370
50Alzheimers disease_Homo sapiens_hsa050100.84300196
51Serotonergic synapse_Homo sapiens_hsa047260.83966410
52Dopaminergic synapse_Homo sapiens_hsa047280.80607217
53RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.80416849
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.79931271
55RNA degradation_Homo sapiens_hsa030180.77568370
56Selenocompound metabolism_Homo sapiens_hsa004500.77297623
57African trypanosomiasis_Homo sapiens_hsa051430.74600380
58Metabolic pathways_Homo sapiens_hsa011000.73484127
59p53 signaling pathway_Homo sapiens_hsa041150.70987709
60ABC transporters_Homo sapiens_hsa020100.70149731
61Renin secretion_Homo sapiens_hsa049240.69684147
62Amphetamine addiction_Homo sapiens_hsa050310.68579163
63Glycerophospholipid metabolism_Homo sapiens_hsa005640.68378795
64Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.66863372
65Circadian entrainment_Homo sapiens_hsa047130.66655401
66Chemical carcinogenesis_Homo sapiens_hsa052040.65843740
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63992986
68N-Glycan biosynthesis_Homo sapiens_hsa005100.63523456
69Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60296058
70Glutamatergic synapse_Homo sapiens_hsa047240.59898632
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59427355
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57307274
73Proteasome_Homo sapiens_hsa030500.55832066
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54351837
75Carbon metabolism_Homo sapiens_hsa012000.54288263
76Base excision repair_Homo sapiens_hsa034100.54151598
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53267481
78Arachidonic acid metabolism_Homo sapiens_hsa005900.52479942
79Regulation of autophagy_Homo sapiens_hsa041400.51693637
80Long-term depression_Homo sapiens_hsa047300.50049199
81Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.48272414
82Caffeine metabolism_Homo sapiens_hsa002320.47789104
83cAMP signaling pathway_Homo sapiens_hsa040240.47557546
84GABAergic synapse_Homo sapiens_hsa047270.46957485
85Olfactory transduction_Homo sapiens_hsa047400.46633805
86Taste transduction_Homo sapiens_hsa047420.46126497
87Other glycan degradation_Homo sapiens_hsa005110.45961237
88Calcium signaling pathway_Homo sapiens_hsa040200.45947047
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.45094185
90One carbon pool by folate_Homo sapiens_hsa006700.44784765
91Pancreatic secretion_Homo sapiens_hsa049720.43810230
92Glycerolipid metabolism_Homo sapiens_hsa005610.43009195
93Ovarian steroidogenesis_Homo sapiens_hsa049130.40484875
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40363784
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.39479246
96Lysine degradation_Homo sapiens_hsa003100.37136729
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36637781
98Tyrosine metabolism_Homo sapiens_hsa003500.35709871
99Complement and coagulation cascades_Homo sapiens_hsa046100.32368701
100Retinol metabolism_Homo sapiens_hsa008300.31770186

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