CEACAM19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of water loss via skin (GO:0033561)9.64791155
2keratinization (GO:0031424)9.21577405
3multicellular organismal water homeostasis (GO:0050891)6.56828298
4keratinocyte differentiation (GO:0030216)6.22386622
5sphingoid metabolic process (GO:0046519)5.84796353
6behavioral response to nicotine (GO:0035095)5.83460238
7hair cycle (GO:0042633)5.60170310
8molting cycle (GO:0042303)5.60170310
9keratinocyte proliferation (GO:0043616)5.49965731
10regulation of somitogenesis (GO:0014807)5.38503036
11sphingosine metabolic process (GO:0006670)5.35150899
12water homeostasis (GO:0030104)5.34456369
13glucosamine-containing compound catabolic process (GO:1901072)5.23126717
14epidermal cell differentiation (GO:0009913)4.97570908
15keratinocyte development (GO:0003334)4.89580516
16diol metabolic process (GO:0034311)4.81340490
17peptide cross-linking (GO:0018149)4.69384188
18hemidesmosome assembly (GO:0031581)4.66534050
19epidermis development (GO:0008544)4.56971861
20G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.46858272
21intermediate filament organization (GO:0045109)4.39657196
22bundle of His cell to Purkinje myocyte communication (GO:0086069)4.35422582
23long-chain fatty acid biosynthetic process (GO:0042759)4.35419568
24regulation of phospholipase A2 activity (GO:0032429)4.30975684
25detection of bacterium (GO:0016045)4.28651582
26ectoderm development (GO:0007398)4.16242770
27detection of other organism (GO:0098543)4.11670323
28L-fucose catabolic process (GO:0042355)4.10894827
29fucose catabolic process (GO:0019317)4.10894827
30L-fucose metabolic process (GO:0042354)4.10894827
31positive regulation of interleukin-8 secretion (GO:2000484)4.10883209
32negative regulation of keratinocyte proliferation (GO:0010839)4.08044826
33cellular ketone body metabolic process (GO:0046950)4.02770583
34regulation of chemokine secretion (GO:0090196)3.98258851
35indolalkylamine metabolic process (GO:0006586)3.88391827
36regulation of cell proliferation involved in kidney development (GO:1901722)3.81130693
37indole-containing compound catabolic process (GO:0042436)3.71109231
38indolalkylamine catabolic process (GO:0046218)3.71109231
39tryptophan catabolic process (GO:0006569)3.71109231
40regulation of interleukin-8 secretion (GO:2000482)3.68478474
41lipoxygenase pathway (GO:0019372)3.61505849
42ketone body metabolic process (GO:1902224)3.61486767
43protein polyglutamylation (GO:0018095)3.47423038
44monocyte chemotaxis (GO:0002548)3.37338897
45water-soluble vitamin biosynthetic process (GO:0042364)3.36824573
46drug catabolic process (GO:0042737)3.36244024
47detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.34940256
48nephron tubule morphogenesis (GO:0072078)3.34704830
49nephron epithelium morphogenesis (GO:0072088)3.34704830
50superoxide anion generation (GO:0042554)3.32991860
51gland morphogenesis (GO:0022612)3.32392266
52regulation of male gonad development (GO:2000018)3.32043000
53positive regulation of hair follicle development (GO:0051798)3.28376905
54positive regulation of hair cycle (GO:0042635)3.28376905
55epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.27614399
56kynurenine metabolic process (GO:0070189)3.26814810
57detection of light stimulus involved in visual perception (GO:0050908)3.26569505
58detection of light stimulus involved in sensory perception (GO:0050962)3.26569505
59regulation of ruffle assembly (GO:1900027)3.23403470
60exogenous drug catabolic process (GO:0042738)3.22519031
61positive regulation of odontogenesis (GO:0042482)3.20295857
62cornea development in camera-type eye (GO:0061303)3.19800600
63axoneme assembly (GO:0035082)3.16350522
64G-protein coupled receptor internalization (GO:0002031)3.15072745
65regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.14867047
66positive regulation of chemokine secretion (GO:0090197)3.14118070
67tryptophan metabolic process (GO:0006568)3.13875761
68positive regulation of mitochondrial membrane permeability (GO:0035794)3.12514796
69protein localization to cilium (GO:0061512)3.11640817
70chemical homeostasis within a tissue (GO:0048875)3.10504056
71cyclooxygenase pathway (GO:0019371)3.07372684
72glycerophospholipid catabolic process (GO:0046475)3.06272650
73S-adenosylmethionine metabolic process (GO:0046500)3.02980014
74regulation of keratinocyte proliferation (GO:0010837)3.02929622
75interferon-gamma secretion (GO:0072643)3.01784486
76piRNA metabolic process (GO:0034587)2.94270119
77atrioventricular valve morphogenesis (GO:0003181)2.92656139
78cellular biogenic amine catabolic process (GO:0042402)2.91706396
79amine catabolic process (GO:0009310)2.91706396
80neural crest cell development (GO:0014032)2.91070239
81synaptic transmission, cholinergic (GO:0007271)2.90945440
82DNA deamination (GO:0045006)2.89522911
83regulation of action potential (GO:0098900)2.88717785
84indole-containing compound metabolic process (GO:0042430)2.86609132
85limb bud formation (GO:0060174)2.84382886
86negative regulation of stress fiber assembly (GO:0051497)2.83982179
87primary amino compound metabolic process (GO:1901160)2.82978410
88mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.82963437
89mitochondrial respiratory chain complex I assembly (GO:0032981)2.82963437
90NADH dehydrogenase complex assembly (GO:0010257)2.82963437
91respiratory chain complex IV assembly (GO:0008535)2.82584014
92pyrimidine nucleobase catabolic process (GO:0006208)2.82045666
93positive regulation of interleukin-1 beta secretion (GO:0050718)2.81930108
94protein complex biogenesis (GO:0070271)2.81765713
95startle response (GO:0001964)2.81740894
96retinal cone cell development (GO:0046549)2.81731173
97positive regulation of fatty acid transport (GO:2000193)2.81510027
98epithelial cilium movement (GO:0003351)2.80923892
99detection of external biotic stimulus (GO:0098581)2.80783223
100dendritic spine morphogenesis (GO:0060997)2.80574662
101regulation of hypersensitivity (GO:0002883)2.80351109
102establishment of tissue polarity (GO:0007164)2.78903510
103establishment of planar polarity (GO:0001736)2.78903510
104aromatic amino acid family catabolic process (GO:0009074)2.77182280
105regulation of transforming growth factor beta1 production (GO:0032908)2.74877773
106kidney morphogenesis (GO:0060993)2.74616892
107DNA methylation involved in gamete generation (GO:0043046)2.74205088
108peristalsis (GO:0030432)2.73346769
109T-helper cell differentiation (GO:0042093)2.71807553
110CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.71807553
111histone H3-K36 demethylation (GO:0070544)2.71350482
112sympathetic nervous system development (GO:0048485)2.70977161
113planar cell polarity pathway involved in neural tube closure (GO:0090179)2.70598138
114phosphatidylinositol acyl-chain remodeling (GO:0036149)2.70382603
115positive regulation of male gonad development (GO:2000020)2.70142282
116nucleobase catabolic process (GO:0046113)2.70133697
117positive regulation of heat generation (GO:0031652)2.69697795
118regulation of glomerular filtration (GO:0003093)2.69397387
119ubiquinone biosynthetic process (GO:0006744)2.69320120
120renal tubule morphogenesis (GO:0061333)2.68423707
121negative regulation of mast cell activation (GO:0033004)2.68213436
122adaptation of signaling pathway (GO:0023058)2.67235909
123GPI anchor metabolic process (GO:0006505)2.67028480
124reflex (GO:0060004)2.66422535
125platelet dense granule organization (GO:0060155)2.66419096
126skin morphogenesis (GO:0043589)2.65856515
127oxidative demethylation (GO:0070989)2.65252659
128neuronal action potential (GO:0019228)2.65232657
129regulation of hair follicle development (GO:0051797)2.65116324
130regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.64772201
131positive regulation of glomerulus development (GO:0090193)2.64619648
132amino sugar catabolic process (GO:0046348)2.64127611
133intermediate filament cytoskeleton organization (GO:0045104)2.63775465
134nonmotile primary cilium assembly (GO:0035058)2.62607595
135G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.62411657
136regulation of hippo signaling (GO:0035330)2.61789983
137purinergic nucleotide receptor signaling pathway (GO:0035590)2.61504356
138intermediate filament-based process (GO:0045103)2.60981842
139phasic smooth muscle contraction (GO:0014821)2.60604404
140regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.60373643
141preassembly of GPI anchor in ER membrane (GO:0016254)2.59030391
142alanine transport (GO:0032328)2.58817695
143negative regulation of telomere maintenance (GO:0032205)2.57659802
144positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.57634245
145phospholipid scrambling (GO:0017121)2.57260710
146positive regulation of interleukin-1 secretion (GO:0050716)2.56648525
147regulation of hair cycle (GO:0042634)2.55161649
148eyelid development in camera-type eye (GO:0061029)2.54950800
149ubiquinone metabolic process (GO:0006743)2.53704454
150serotonin metabolic process (GO:0042428)2.53248201
151positive regulation of icosanoid secretion (GO:0032305)2.53123868
152negative regulation of synaptic transmission, GABAergic (GO:0032229)2.52721272
153arginine metabolic process (GO:0006525)2.52667197
154negative regulation of stem cell proliferation (GO:2000647)2.51983162
155positive regulation of interleukin-1 beta production (GO:0032731)2.50328821
156surfactant homeostasis (GO:0043129)2.49249452
157positive regulation of sodium ion transmembrane transport (GO:1902307)2.49183992
158positive regulation of epidermis development (GO:0045684)2.47832738
159photoreceptor cell maintenance (GO:0045494)2.47690048
160sulfation (GO:0051923)2.47564878
161alkaloid metabolic process (GO:0009820)2.47521944
162mitochondrial respiratory chain complex assembly (GO:0033108)2.47320196
163positive regulation of prostaglandin secretion (GO:0032308)2.47196399
164negative regulation of cell fate specification (GO:0009996)2.47100060
165membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.46382175
166inositol phosphate catabolic process (GO:0071545)2.45949055
167mannosylation (GO:0097502)2.45444303
168epithelium development (GO:0060429)2.44627746
169gamma-aminobutyric acid transport (GO:0015812)2.44285988
170cilium morphogenesis (GO:0060271)2.44236742
171C4-dicarboxylate transport (GO:0015740)2.44033590
172positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.43929724
173positive regulation of monocyte chemotaxis (GO:0090026)2.43584107
174eosinophil chemotaxis (GO:0048245)2.43071576
175regulation of fever generation (GO:0031620)2.42722659
176positive regulation of cholesterol efflux (GO:0010875)2.41243796
177regulation of hexokinase activity (GO:1903299)2.40286495
178regulation of glucokinase activity (GO:0033131)2.40286495
179auditory receptor cell stereocilium organization (GO:0060088)2.40171710
180negative regulation of axon guidance (GO:1902668)2.39385781
181detection of biotic stimulus (GO:0009595)2.38722350
182rhodopsin mediated signaling pathway (GO:0016056)2.38234623
183cytochrome complex assembly (GO:0017004)2.37735605
184lymph vessel development (GO:0001945)2.36712299
185action potential (GO:0001508)2.36658121
186sulfate transmembrane transport (GO:1902358)2.36273437
187inositol phosphate dephosphorylation (GO:0046855)2.36137910
188phosphorylated carbohydrate dephosphorylation (GO:0046838)2.36137910
189negative regulation of reactive oxygen species metabolic process (GO:2000378)2.36008496
190transepithelial transport (GO:0070633)2.35364723
191cell morphogenesis involved in neuron differentiation (GO:0048667)2.35092249
192organic cation transport (GO:0015695)2.34886252
193arginine catabolic process (GO:0006527)2.34306225
194transmission of nerve impulse (GO:0019226)2.34168430
195regulation of interleukin-1 beta secretion (GO:0050706)2.34101503
196G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.33494716
197cilium organization (GO:0044782)2.33350416
198desmosome organization (GO:0002934)11.9154660
199establishment of skin barrier (GO:0061436)11.1066623

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.58493467
2ZNF274_21170338_ChIP-Seq_K562_Hela3.54017013
3EZH2_22144423_ChIP-Seq_EOC_Human3.00040476
4VDR_22108803_ChIP-Seq_LS180_Human2.98250628
5SOX9_24532713_ChIP-Seq_HFSC_Mouse2.65456452
6AR_21572438_ChIP-Seq_LNCaP_Human2.64604220
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.57077752
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53436538
9* P63_26484246_Chip-Seq_KERATINOCYTES_Human2.20956180
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.07493407
11TP63_17297297_ChIP-ChIP_HaCaT_Human11.7665852
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.99223913
13CTBP1_25329375_ChIP-Seq_LNCAP_Human1.96767684
14STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96179749
15ZFP57_27257070_Chip-Seq_ESCs_Mouse1.95736064
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.88353563
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83340508
18ZNF217_24962896_ChIP-Seq_MCF-7_Human1.76408780
19BMI1_23680149_ChIP-Seq_NPCS_Mouse1.76039989
20EED_16625203_ChIP-ChIP_MESCs_Mouse1.72088188
21FUS_26573619_Chip-Seq_HEK293_Human1.71763803
22ESR1_21235772_ChIP-Seq_MCF-7_Human1.70514804
23E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.69907929
24ER_23166858_ChIP-Seq_MCF-7_Human1.69530737
25RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62698956
26SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.58931114
27EZH2_27304074_Chip-Seq_ESCs_Mouse1.58818847
28EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.58086368
29REST_21632747_ChIP-Seq_MESCs_Mouse1.54651051
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54640642
31TCF4_18268006_ChIP-ChIP_LS174T_Human1.54146289
32SUZ12_27294783_Chip-Seq_NPCs_Mouse1.54098275
33CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.53904208
34GBX2_23144817_ChIP-Seq_PC3_Human1.53511104
35SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.53127809
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51971027
37PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.50706447
38SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.49994845
39SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.49994845
40IGF1R_20145208_ChIP-Seq_DFB_Human1.49855095
41RNF2_27304074_Chip-Seq_NSC_Mouse1.49679449
42BP1_19119308_ChIP-ChIP_Hs578T_Human1.48270258
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.48098984
44TP53_18474530_ChIP-ChIP_U2OS_Human1.48021397
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.44774081
46STAT3_23295773_ChIP-Seq_U87_Human1.42345181
47PCGF2_27294783_Chip-Seq_NPCs_Mouse1.42295266
48CJUN_26792858_Chip-Seq_BT549_Human1.42294711
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41037311
50CBP_20019798_ChIP-Seq_JUKART_Human1.41037311
51CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.39984453
52JARID2_20064375_ChIP-Seq_MESCs_Mouse1.39619409
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.39280503
54DROSHA_22980978_ChIP-Seq_HELA_Human1.39214262
55TP53_22573176_ChIP-Seq_HFKS_Human1.37935771
56RNF2_27304074_Chip-Seq_ESCs_Mouse1.37793020
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.37597967
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.36337593
59NR3C1_21868756_ChIP-Seq_MCF10A_Human1.34682498
60EZH2_27294783_Chip-Seq_NPCs_Mouse1.33549653
61RXR_22108803_ChIP-Seq_LS180_Human1.33469355
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33179790
63ETV2_25802403_ChIP-Seq_MESCs_Mouse1.32913349
64TCF4_23295773_ChIP-Seq_U87_Human1.30936807
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30893143
66PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.30635209
67GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.30127313
68EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.28125953
69TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26381747
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26381747
71NCOR_22424771_ChIP-Seq_293T_Human1.25706672
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24494922
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22966781
74* GATA3_21878914_ChIP-Seq_MCF-7_Human1.22752120
75EGR1_23403033_ChIP-Seq_LIVER_Mouse1.22527586
76FOXA1_27270436_Chip-Seq_PROSTATE_Human1.22344006
77FOXA1_25329375_ChIP-Seq_VCAP_Human1.22344006
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21901172
79SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.21420540
80TP53_16413492_ChIP-PET_HCT116_Human1.21274393
81TP63_23658742_ChIP-Seq_EP156T_Human1.20794460
82PIAS1_25552417_ChIP-Seq_VCAP_Human1.20776900
83EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20454853
84NANOG_19829295_ChIP-Seq_ESCs_Human1.18592611
85SOX2_19829295_ChIP-Seq_ESCs_Human1.18592611
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18350953
87GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.18186596
88MYC_19829295_ChIP-Seq_ESCs_Human1.17604363
89Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.16767323
90RUNX2_22187159_ChIP-Seq_PCA_Human1.16025265
91NANOG_18555785_Chip-Seq_ESCs_Mouse1.15886119
92E2F1_18555785_Chip-Seq_ESCs_Mouse1.15655123
93STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.15385270
94SMAD4_21741376_ChIP-Seq_EPCs_Human1.14581467
95TRIM28_21343339_ChIP-Seq_HEK293_Human1.14521103
96SUZ12_27294783_Chip-Seq_ESCs_Mouse1.14305802
97JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13789797
98GATA6_21074721_ChIP-Seq_CACO-2_Human1.13763940
99AHR_22903824_ChIP-Seq_MCF-7_Human1.12997592
100SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.12353333
101SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.11945204
102AR_20517297_ChIP-Seq_VCAP_Human1.10920861
103ERA_21632823_ChIP-Seq_H3396_Human1.10736830
104CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.10381942
105P300_19829295_ChIP-Seq_ESCs_Human1.09451322
106FLI1_27457419_Chip-Seq_LIVER_Mouse1.09316364
107HOXB7_26014856_ChIP-Seq_BT474_Human1.09027841
108BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.08907211
109TP63_19390658_ChIP-ChIP_HaCaT_Human1.08735813
110REST_18959480_ChIP-ChIP_MESCs_Mouse1.08067048
111SOX2_20726797_ChIP-Seq_SW620_Human1.07990982
112SUZ12_18555785_Chip-Seq_ESCs_Mouse1.07801067
113TAF15_26573619_Chip-Seq_HEK293_Human1.07665524
114SMAD3_21741376_ChIP-Seq_EPCs_Human1.07094756
115TCF4_22108803_ChIP-Seq_LS180_Human1.06881885
116EZH2_27294783_Chip-Seq_ESCs_Mouse1.06003969
117ARNT_22903824_ChIP-Seq_MCF-7_Human1.05943437
118TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04470119
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.02792788
120SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.02666216
121CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02152607
122POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01541983
123P53_22387025_ChIP-Seq_ESCs_Mouse1.01518432
124PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.01509456
125CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.01388123
126CMYC_18555785_Chip-Seq_ESCs_Mouse1.01078386
127TP53_20018659_ChIP-ChIP_R1E_Mouse1.01007924
128SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.00146898
129STAT3_18555785_Chip-Seq_ESCs_Mouse1.00139610
130ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.99938927
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99746341
132CDX2_22108803_ChIP-Seq_LS180_Human0.99338269
133STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.99238813
134OCT4_18555785_Chip-Seq_ESCs_Mouse0.99097181
135OCT4_20526341_ChIP-Seq_ESCs_Human0.98352582
136TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97554989
137EWS_26573619_Chip-Seq_HEK293_Human0.97213015
138TAF2_19829295_ChIP-Seq_ESCs_Human0.96811086
139CRX_20693478_ChIP-Seq_RETINA_Mouse0.96749160
140CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96659976
141PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.96563317
142FOXA1_21572438_ChIP-Seq_LNCaP_Human0.96396166
143* FOXH1_21741376_ChIP-Seq_EPCs_Human0.96218279
144NMYC_18555785_Chip-Seq_ESCs_Mouse0.95990768
145FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95787533
146AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94938028
147CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94921322
148EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.94804326
149BCAT_22108803_ChIP-Seq_LS180_Human0.93425505
150SMAD4_21799915_ChIP-Seq_A2780_Human0.93275651
151EZH2_18974828_ChIP-Seq_MESCs_Mouse0.92592326
152RNF2_18974828_ChIP-Seq_MESCs_Mouse0.92592326
153RBPJ_21746931_ChIP-Seq_IB4_Human0.92097717
154CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.92033664
155CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.91894272
156POU3F2_20337985_ChIP-ChIP_501MEL_Human0.91323292
157MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90884850
158HNFA_21074721_ChIP-Seq_CACO-2_Human0.90238700
159RUNX1_27457419_Chip-Seq_LIVER_Mouse0.89226254
160PU1_27457419_Chip-Seq_LIVER_Mouse0.88088354
161AR_25329375_ChIP-Seq_VCAP_Human0.88086414
162CTCF_18555785_Chip-Seq_ESCs_Mouse0.86973173

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier6.58708205
2MP0003941_abnormal_skin_development5.49751867
3MP0010234_abnormal_vibrissa_follicle5.04496668
4MP0005275_abnormal_skin_tensile4.95869974
5MP0004381_abnormal_hair_follicle4.65283062
6MP0000579_abnormal_nail_morphology4.23371566
7MP0005501_abnormal_skin_physiology4.19749483
8MP0002098_abnormal_vibrissa_morphology3.40641044
9MP0003195_calcinosis3.29792865
10MP0003646_muscle_fatigue3.17492590
11MP0000566_synostosis3.12365697
12MP0005451_abnormal_body_composition3.07440935
13MP0001216_abnormal_epidermal_layer3.05049189
14MP0002060_abnormal_skin_morphology3.01268174
15MP0000383_abnormal_hair_follicle2.86643484
16MP0010678_abnormal_skin_adnexa2.84647601
17MP0002837_dystrophic_cardiac_calcinosis2.71006767
18MP0001346_abnormal_lacrimal_gland2.62682807
19MP0010771_integument_phenotype2.60154353
20MP0000647_abnormal_sebaceous_gland2.58272103
21MP0002876_abnormal_thyroid_physiology2.41948392
22MP0005551_abnormal_eye_electrophysiolog2.40110181
23MP0000377_abnormal_hair_follicle2.26567785
24MP0008875_abnormal_xenobiotic_pharmacok2.24148733
25MP0003453_abnormal_keratinocyte_physiol2.21286810
26MP0004043_abnormal_pH_regulation2.16442192
27MP0008877_abnormal_DNA_methylation2.14746522
28MP0000427_abnormal_hair_cycle2.13997726
29MP0001968_abnormal_touch/_nociception2.13893848
30MP0009046_muscle_twitch2.09783555
31MP0004145_abnormal_muscle_electrophysio2.09056993
32MP0004947_skin_inflammation2.07929202
33MP0003136_yellow_coat_color2.05385858
34MP0001501_abnormal_sleep_pattern1.99964273
35MP0001986_abnormal_taste_sensitivity1.97559515
36MP0006276_abnormal_autonomic_nervous1.94486984
37MP0004142_abnormal_muscle_tone1.93209748
38MP0005257_abnormal_intraocular_pressure1.86474894
39MP0004133_heterotaxia1.83601323
40MP0009745_abnormal_behavioral_response1.78637122
41MP0002638_abnormal_pupillary_reflex1.76645676
42MP0000569_abnormal_digit_pigmentation1.76536274
43MP0005646_abnormal_pituitary_gland1.72565837
44MP0000762_abnormal_tongue_morphology1.71123722
45MP0003878_abnormal_ear_physiology1.68238220
46MP0005377_hearing/vestibular/ear_phenot1.68238220
47MP0002009_preneoplasia1.67497722
48MP0002254_reproductive_system_inflammat1.66756358
49MP0004147_increased_porphyrin_level1.64056764
50MP0000467_abnormal_esophagus_morphology1.60175775
51MP0008872_abnormal_physiological_respon1.59233514
52MP0000013_abnormal_adipose_tissue1.55437687
53MP0004885_abnormal_endolymph1.55232849
54MP0002272_abnormal_nervous_system1.54936557
55MP0005253_abnormal_eye_physiology1.52910157
56MP0002277_abnormal_respiratory_mucosa1.52881714
57MP0001486_abnormal_startle_reflex1.49367072
58MP0001191_abnormal_skin_condition1.48660505
59MP0002736_abnormal_nociception_after1.43724908
60MP0006072_abnormal_retinal_apoptosis1.43414824
61MP0003122_maternal_imprinting1.43320778
62MP0000465_gastrointestinal_hemorrhage1.42628465
63MP0001502_abnormal_circadian_rhythm1.41850093
64MP0002909_abnormal_adrenal_gland1.41545849
65MP0005365_abnormal_bile_salt1.41080985
66MP0002733_abnormal_thermal_nociception1.38012325
67MP0009931_abnormal_skin_appearance1.36413874
68MP0005332_abnormal_amino_acid1.35298891
69MP0003137_abnormal_impulse_conducting1.32437656
70MP0005248_abnormal_Harderian_gland1.29395021
71MP0001851_eye_inflammation1.29311367
72MP0002234_abnormal_pharynx_morphology1.28877510
73MP0002163_abnormal_gland_morphology1.28635617
74MP0010329_abnormal_lipoprotein_level1.27650879
75MP0000367_abnormal_coat/_hair1.26369237
76MP0004215_abnormal_myocardial_fiber1.26238904
77MP0002572_abnormal_emotion/affect_behav1.25556972
78MP0005367_renal/urinary_system_phenotyp1.25379356
79MP0000516_abnormal_urinary_system1.25379356
80MP0001970_abnormal_pain_threshold1.24005165
81MP0005174_abnormal_tail_pigmentation1.22370425
82MP0002064_seizures1.21674680
83MP0003191_abnormal_cellular_cholesterol1.21346919
84MP0002138_abnormal_hepatobiliary_system1.18932236
85MP0000631_abnormal_neuroendocrine_gland1.18856982
86MP0002735_abnormal_chemical_nociception1.18618067
87MP0005386_behavior/neurological_phenoty1.17688875
88MP0004924_abnormal_behavior1.17688875
89MP0000230_abnormal_systemic_arterial1.17552597
90MP0001529_abnormal_vocalization1.16725891
91MP0005075_abnormal_melanosome_morpholog1.14995910
92MP0002938_white_spotting1.14737297
93MP0009379_abnormal_foot_pigmentation1.13376713
94MP0002557_abnormal_social/conspecific_i1.13050924
95MP0005085_abnormal_gallbladder_physiolo1.11672353
96MP0008775_abnormal_heart_ventricle1.10082747
97MP0005360_urolithiasis1.08736911
98MP0003121_genomic_imprinting1.08185031
99MP0004782_abnormal_surfactant_physiolog1.07902263
100MP0001485_abnormal_pinna_reflex1.07555988
101MP0003566_abnormal_cell_adhesion1.07278706
102MP0004185_abnormal_adipocyte_glucose1.07100262
103MP0009780_abnormal_chondrocyte_physiolo1.05904667
104MP0001905_abnormal_dopamine_level1.04457363
105MP0003635_abnormal_synaptic_transmissio1.04137464
106MP0002063_abnormal_learning/memory/cond1.03329029
107MP0002160_abnormal_reproductive_system1.03230898
108MP0003880_abnormal_central_pattern1.03175603
109MP0002653_abnormal_ependyma_morphology1.01567354
110MP0002148_abnormal_hypersensitivity_rea1.01016364
111MP0002734_abnormal_mechanical_nocicepti1.01014302
112MP0000372_irregular_coat_pigmentation1.00665666
113MP0004085_abnormal_heartbeat1.00136192
114MP0002139_abnormal_hepatobiliary_system1.00022705
115MP0003045_fibrosis0.97969128
116MP0001984_abnormal_olfaction0.97962336
117MP0010030_abnormal_orbit_morphology0.97836571
118MP0002067_abnormal_sensory_capabilities0.96021997
119MP0002095_abnormal_skin_pigmentation0.95419883
120MP0005379_endocrine/exocrine_gland_phen0.94686697
121MP0005195_abnormal_posterior_eye0.94586139
122MP0005167_abnormal_blood-brain_barrier0.94196510
123MP0001243_abnormal_dermal_layer0.92815150
124MP0005084_abnormal_gallbladder_morpholo0.92090793
125MP0001188_hyperpigmentation0.91931158
126MP0005389_reproductive_system_phenotype0.89632207
127MP0003755_abnormal_palate_morphology0.89385961
128MP0000538_abnormal_urinary_bladder0.89133777
129MP0005409_darkened_coat_color0.88380634
130MP0002132_abnormal_respiratory_system0.88122811
131MP0002822_catalepsy0.88027225
132MP0004084_abnormal_cardiac_muscle0.87733070
133MP0004130_abnormal_muscle_cell0.86980020
134MP0002928_abnormal_bile_duct0.81599379
135MP0001324_abnormal_eye_pigmentation0.80991427
136MP0010386_abnormal_urinary_bladder0.80924247
137MP0002693_abnormal_pancreas_physiology0.80806383
138MP0001340_abnormal_eyelid_morphology0.79101513
139MP0005448_abnormal_energy_balance0.78895723
140MP0005171_absent_coat_pigmentation0.76004823
141MP0002249_abnormal_larynx_morphology0.74525357
142MP0003705_abnormal_hypodermis_morpholog0.74279956
143MP0003436_decreased_susceptibility_to0.73649857
144MP0003950_abnormal_plasma_membrane0.73480136
145MP0008004_abnormal_stomach_pH0.71528429
146MP0009250_abnormal_appendicular_skeleto0.70485648
147MP0002177_abnormal_outer_ear0.63871670
148MP0002102_abnormal_ear_morphology0.62514633
149MP0010352_gastrointestinal_tract_polyps0.59765294
150MP0009697_abnormal_copulation0.57106270
151MP0001919_abnormal_reproductive_system0.55729343
152MP0003011_delayed_dark_adaptation0.55725919
153MP0002006_tumorigenesis0.55017828
154MP0000627_abnormal_mammary_gland0.54921443
155MP0002233_abnormal_nose_morphology0.53954599
156MP0003787_abnormal_imprinting0.53547764
157MP0000432_abnormal_head_morphology0.52959600
158MP0002109_abnormal_limb_morphology0.52627114
159MP0005508_abnormal_skeleton_morphology0.52389980
160MP0003315_abnormal_perineum_morphology0.50739732
161MP0002111_abnormal_tail_morphology0.49354696
162MP0005645_abnormal_hypothalamus_physiol0.49292136
163MP0009384_cardiac_valve_regurgitation0.48903380
164MP0006292_abnormal_olfactory_placode0.47726756
165MP0005197_abnormal_uvea_morphology0.46512899
166MP0003385_abnormal_body_wall0.45806022
167MP0003763_abnormal_thymus_physiology0.44760472
168MP0000470_abnormal_stomach_morphology0.44423970
169MP0005076_abnormal_cell_differentiation0.44419045
170MP0002998_abnormal_bone_remodeling0.44393665
171MP0006054_spinal_hemorrhage0.44209818
172MP0008789_abnormal_olfactory_epithelium0.44161666
173MP0003183_abnormal_peptide_metabolism0.44101070
174MP0005390_skeleton_phenotype0.43758127
175MP0005187_abnormal_penis_morphology0.43519677
176MP0009764_decreased_sensitivity_to0.42409893
177MP0008995_early_reproductive_senescence0.42073535
178MP0003828_pulmonary_edema0.41261218
179MP0005310_abnormal_salivary_gland0.40183486
180MP0002396_abnormal_hematopoietic_system0.40170957
181MP0001784_abnormal_fluid_regulation0.39754520
182MP0001286_abnormal_eye_development0.39595962

Predicted human phenotypes

RankGene SetZ-score
1Increased IgE level (HP:0003212)6.59488968
2Abnormality of nail color (HP:0100643)6.59004072
3Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.68026155
4Congenital ichthyosiform erythroderma (HP:0007431)5.61119580
5Hypotrichosis (HP:0001006)5.49903771
6Lip pit (HP:0100267)5.43296082
7Parakeratosis (HP:0001036)5.31869731
8Palmoplantar hyperkeratosis (HP:0000972)5.19460655
9Plantar hyperkeratosis (HP:0007556)5.17271169
10Palmar hyperkeratosis (HP:0010765)4.95337749
11Erythroderma (HP:0001019)4.62808317
12Woolly hair (HP:0002224)4.52871869
13Pancreatic cysts (HP:0001737)4.24392042
14Onycholysis (HP:0001806)4.22345298
15Erythema (HP:0010783)4.17122417
16Abnormality of midbrain morphology (HP:0002418)4.16916131
17Molar tooth sign on MRI (HP:0002419)4.16916131
18Sparse scalp hair (HP:0002209)4.05885112
19Right ventricular cardiomyopathy (HP:0011663)4.00439530
20Ectropion (HP:0000656)3.98315429
21Type II lissencephaly (HP:0007260)3.96840748
22Congenital stationary night blindness (HP:0007642)3.93468323
23Natal tooth (HP:0000695)3.92105463
24Pancreatic fibrosis (HP:0100732)3.76174809
25Abnormality of the renal cortex (HP:0011035)3.76016759
26Thick nail (HP:0001805)3.72215982
27Nephronophthisis (HP:0000090)3.68809594
28Gangrene (HP:0100758)3.48648650
29True hermaphroditism (HP:0010459)3.41209040
30Aplasia cutis congenita (HP:0001057)3.32411301
31Chronic hepatic failure (HP:0100626)3.31127956
32Medial flaring of the eyebrow (HP:0010747)3.30661296
33Attenuation of retinal blood vessels (HP:0007843)3.29532345
34Abnormality of the renal medulla (HP:0100957)3.28685938
35Corneal erosion (HP:0200020)3.25944050
36Fragile nails (HP:0001808)3.23785260
37Advanced eruption of teeth (HP:0006288)3.14712086
38Tubular atrophy (HP:0000092)3.13222191
39Hypohidrosis (HP:0000966)3.11924677
40Abnormal blistering of the skin (HP:0008066)3.09892853
41Polydipsia (HP:0001959)2.98147296
42Abnormal drinking behavior (HP:0030082)2.98147296
43Curly hair (HP:0002212)2.96517292
44Oligodontia (HP:0000677)2.85657643
45Renal cortical cysts (HP:0000803)2.82674468
46Hypothermia (HP:0002045)2.81258375
47Cystic liver disease (HP:0006706)2.77107767
48Distal lower limb muscle weakness (HP:0009053)2.75934517
49Hyperventilation (HP:0002883)2.74003611
50Decreased central vision (HP:0007663)2.72392804
51Keratoconus (HP:0000563)2.71825771
52Increased corneal curvature (HP:0100692)2.71825771
53Lissencephaly (HP:0001339)2.71243750
54Pruritus (HP:0000989)2.68923434
55Sparse eyelashes (HP:0000653)2.66909049
56Abnormality of secondary sexual hair (HP:0009888)2.63432752
57Abnormality of the axillary hair (HP:0100134)2.63432752
58Gait imbalance (HP:0002141)2.62711499
59Nail dystrophy (HP:0008404)2.62355354
60Abnormal rod and cone electroretinograms (HP:0008323)2.61861694
61Alopecia of scalp (HP:0002293)2.59248466
62Cerebellar dysplasia (HP:0007033)2.57183230
63Corneal dystrophy (HP:0001131)2.53958821
64Decreased electroretinogram (ERG) amplitude (HP:0000654)2.51089106
65Abolished electroretinogram (ERG) (HP:0000550)2.49951450
66Conical tooth (HP:0000698)2.49363597
67Retinal dysplasia (HP:0007973)2.47138563
68Dry hair (HP:0011359)2.47052590
69Mesangial abnormality (HP:0001966)2.44629278
70Congenital primary aphakia (HP:0007707)2.43901707
71Milia (HP:0001056)2.43196653
72Popliteal pterygium (HP:0009756)2.40358971
73Palmoplantar keratoderma (HP:0000982)2.39038235
74Polyuria (HP:0000103)2.37061833
75Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31298043
76Pachygyria (HP:0001302)2.30701047
77Acute necrotizing encephalopathy (HP:0006965)2.30046112
78Congenital hepatic fibrosis (HP:0002612)2.29974336
79Sclerocornea (HP:0000647)2.29845395
80Large for gestational age (HP:0001520)2.29479520
81Mitochondrial inheritance (HP:0001427)2.28709423
82Prostate neoplasm (HP:0100787)2.27828047
83Eczematoid dermatitis (HP:0000976)2.26848303
84Pendular nystagmus (HP:0012043)2.25709024
85Limb dystonia (HP:0002451)2.25570927
86Chorioretinal atrophy (HP:0000533)2.23758820
87Reticulocytopenia (HP:0001896)2.23067337
88Severe muscular hypotonia (HP:0006829)2.22810372
89Aplasia/Hypoplasia of the sacrum (HP:0008517)2.21845041
90Furrowed tongue (HP:0000221)2.20734253
91Pili torti (HP:0003777)2.20410042
92Hypergammaglobulinemia (HP:0010702)2.20226294
93Ketosis (HP:0001946)2.19080243
94Nephrogenic diabetes insipidus (HP:0009806)2.19009879
95Ventricular tachycardia (HP:0004756)2.18677734
96Bony spicule pigmentary retinopathy (HP:0007737)2.17663119
97Delayed CNS myelination (HP:0002188)2.17168404
98Severe Myopia (HP:0011003)2.16857867
99Absent eyebrow (HP:0002223)2.16458978
100Inability to walk (HP:0002540)2.16456801
101Anhidrosis (HP:0000970)2.16337562
102Optic disc pallor (HP:0000543)2.15479881
103Gaze-evoked nystagmus (HP:0000640)2.15366338
104Increased CSF lactate (HP:0002490)2.15039091
105Abnormality of the preputium (HP:0100587)2.12774465
106Broad-based gait (HP:0002136)2.11792510
107White forelock (HP:0002211)2.10440054
108Abnormality of the nasal septum (HP:0000419)2.10207905
109Chromsome breakage (HP:0040012)2.10171042
110Duplicated collecting system (HP:0000081)2.09025905
111Progressive macrocephaly (HP:0004481)2.08366833
112Myelomeningocele (HP:0002475)2.03591391
113Decreased circulating renin level (HP:0003351)2.01394166
114Bile duct proliferation (HP:0001408)2.00736356
115Abnormal biliary tract physiology (HP:0012439)2.00736356
116Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.99184415
117Abnormality of alanine metabolism (HP:0010916)1.99184415
118Hyperalaninemia (HP:0003348)1.99184415
119Hypoplasia of the pons (HP:0012110)1.98848008
120Blepharitis (HP:0000498)1.98368457
121Abnormality of the pons (HP:0007361)1.98343149
122Abnormal urine output (HP:0012590)1.97076509
123Genital tract atresia (HP:0001827)1.96937827
124Abnormality of the renal collecting system (HP:0004742)1.96009090
125Hemiparesis (HP:0001269)1.95195298
126Patchy hypopigmentation of hair (HP:0011365)1.95154004
127Nasolacrimal duct obstruction (HP:0000579)1.94615558
128Progressive cerebellar ataxia (HP:0002073)1.93860379
129Concave nail (HP:0001598)1.93168472
130Congenital, generalized hypertrichosis (HP:0004540)1.92090594
131Ketoacidosis (HP:0001993)1.91583261
132Aplasia/Hypoplasia of the tibia (HP:0005772)1.89550139
133Vaginal atresia (HP:0000148)1.88575928
134Hepatocellular necrosis (HP:0001404)1.88294945
135Congenital sensorineural hearing impairment (HP:0008527)1.88089202
136Dry skin (HP:0000958)1.87669875
137Acute encephalopathy (HP:0006846)1.86917554
138Fair hair (HP:0002286)1.85875873
139Hepatic necrosis (HP:0002605)1.85721030
140Genetic anticipation (HP:0003743)1.85393667
141Dehydration (HP:0001944)1.84010707
142Methylmalonic acidemia (HP:0002912)1.83362693
143Left ventricular hypertrophy (HP:0001712)1.83272732
144Prolonged QT interval (HP:0001657)1.82617785
145Male pseudohermaphroditism (HP:0000037)1.82232945
1463-Methylglutaconic aciduria (HP:0003535)1.80716494
147Follicular hyperkeratosis (HP:0007502)1.80636485
148Anomalous pulmonary venous return (HP:0010772)1.80208943
149Hypoplastic labia majora (HP:0000059)1.80068449
150Volvulus (HP:0002580)1.79769380
151Tachypnea (HP:0002789)1.79451172
152Agitation (HP:0000713)1.79003046
153Aplasia/Hypoplasia of the tongue (HP:0010295)1.78999157
154Upper limb muscle weakness (HP:0003484)1.78056269
155Focal seizures (HP:0007359)1.77202012
156Prominent supraorbital ridges (HP:0000336)1.76470485
157Abnormality of the right ventricle (HP:0001707)1.75572605
158Conjunctival hamartoma (HP:0100780)1.75467110
159Septo-optic dysplasia (HP:0100842)1.75038667
160Lipid accumulation in hepatocytes (HP:0006561)1.74248425
161Retinitis pigmentosa (HP:0000510)1.73909819
162Abnormality of the fetal cardiovascular system (HP:0010948)1.73836487
163Abnormal umbilical cord blood vessels (HP:0011403)1.73836487
164Single umbilical artery (HP:0001195)1.73836487
165Optic nerve hypoplasia (HP:0000609)1.73812680
166Anencephaly (HP:0002323)1.73595734
167Postaxial foot polydactyly (HP:0001830)1.73427259
168Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72777764
169Abnormality of renal excretion (HP:0011036)1.72433460
170Bulbous nose (HP:0000414)1.71930237
171Postaxial hand polydactyly (HP:0001162)1.71796351
172Abnormal mitochondria in muscle tissue (HP:0008316)1.70458293
173Abnormality of the lacrimal duct (HP:0011481)1.70148398
174Poor coordination (HP:0002370)1.70123161
175Abnormality of urine glucose concentration (HP:0011016)1.69849356
176Glycosuria (HP:0003076)1.69849356
177Brittle hair (HP:0002299)1.69607365
178Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.67503998
179Adrenal hypoplasia (HP:0000835)1.67079970
180Epidermoid cyst (HP:0200040)1.66425717
181Acanthosis nigricans (HP:0000956)1.66385813
182Recurrent abscess formation (HP:0002722)1.66365164
183Stomach cancer (HP:0012126)1.64859963
184Abnormality of incisor morphology (HP:0011063)1.64212792
185Laryngomalacia (HP:0001601)1.62453142
186Premature loss of primary teeth (HP:0006323)1.61365854
187Abnormality of the phalanges of the 5th finger (HP:0004213)1.60785868
188Malignant hyperthermia (HP:0002047)1.59970599
189Abnormal sex determination (HP:0012244)1.59560706
190Sex reversal (HP:0012245)1.59560706
191Sepsis (HP:0100806)1.59296649
192Abnormality of the labia majora (HP:0012881)1.57619298
193Abnormality of the pulmonary veins (HP:0011718)1.53794809
194Alveolar cell carcinoma (HP:0006519)1.52957341
195Ulnar claw (HP:0001178)1.50220991
196Skin pits (HP:0100276)1.48765090
197Abnormality of the gastric mucosa (HP:0004295)1.46889804
198Hypoplasia of dental enamel (HP:0006297)1.46439163

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.98524604
2WNK43.14602299
3MAP3K32.90227418
4ACVR1B2.64768636
5LATS12.63255823
6EPHA32.57123335
7MAP4K22.47639768
8WNK32.46214337
9CASK2.44946930
10TLK12.35812090
11GRK72.35507864
12MAP3K142.33125522
13MUSK2.30069111
14TGFBR22.23193726
15ZAK2.22266337
16STK242.21840114
17FER2.15652530
18MST1R2.14855060
19EIF2AK22.12528726
20EPHB22.10551030
21MAPKAPK32.06784741
22DAPK22.00837619
23SRPK11.99590510
24MST41.97430456
25STK38L1.97298106
26CDK31.92730367
27PHKG21.90177254
28PHKG11.90177254
29GRK11.88746729
30MAPK131.84345024
31IRAK31.82242910
32INSRR1.81794719
33SIK31.78175902
34PAK31.77497088
35BLK1.66331378
36PINK11.63855893
37CDK81.62151174
38BMPR1B1.60102842
39MARK11.58234471
40MAP3K61.57613946
41PIM21.57459736
42MAP3K41.49800419
43CAMKK21.41935686
44CDK121.38783887
45NTRK31.33320057
46TAOK31.32947089
47ERBB31.31981733
48OXSR11.31902634
49NUAK11.31447764
50STK31.17674054
51TXK1.16755643
52STK101.12486144
53NTRK21.08247913
54TIE11.08031233
55YES11.05682748
56TAOK21.03440979
57IRAK41.01933378
58MAPK151.00738879
59PBK1.00658749
60TGFBR11.00527228
61STK390.99588987
62NME10.99375335
63BCKDK0.95859535
64ICK0.95449554
65PKN10.93188891
66DYRK20.93046097
67PRKCG0.93012608
68NLK0.91683725
69MAPKAPK20.90259015
70BRD40.90088860
71SIK20.89278649
72FGFR20.86654310
73TRPM70.86352077
74PIK3CA0.86192974
75PTK2B0.84582881
76TEC0.83836317
77BMPR20.81908547
78MAP3K50.81516181
79IKBKB0.81283743
80MAP2K70.80416872
81CSNK1G10.80211033
82TYK20.79501735
83CDK70.78592812
84CSNK1G30.78578720
85IRAK10.76873378
86ADRBK20.74784093
87CSNK1G20.74697520
88BCR0.74319356
89PRKAA20.73854030
90PIK3CG0.73053012
91CDK60.72205007
92MYLK0.72075609
93ITK0.71781480
94CAMK10.71717818
95RPS6KB20.69442594
96CHUK0.67929814
97JAK10.66195338
98MAP2K20.65819329
99STK110.64852377
100CAMK2A0.64571288
101RPS6KA40.64198364
102EPHA40.64049367
103IKBKE0.62478296
104MARK30.60910697
105ERBB20.60771835
106LIMK10.59718314
107CAMK40.59359381
108GRK50.59147232
109RPS6KC10.58324938
110RPS6KL10.58324938
111PRKAA10.56888602
112IRAK20.56306762
113PRKACA0.55851049
114MAPKAPK50.55566418
115SGK20.54507881
116TNIK0.52967527
117ERBB40.52537598
118RIPK40.49960649
119MAP3K20.49685907
120MAP2K40.49107439
121CSNK1A1L0.48567416
122MAPK70.47761009
123PLK20.47463697
124PRKCE0.47133774
125CAMKK10.46693411
126OBSCN0.46269144
127PRKCI0.46120846
128KIT0.46042755
129MKNK20.45857067
130MAP2K60.44745675
131MAP2K10.44047112
132PRKCZ0.43438768
133MARK20.43043436
134TNK20.41779489
135AKT20.41436578
136RPS6KA60.41132511
137EPHA20.40487787
138ADRBK10.40397967
139TBK10.39800247
140RPS6KA20.38138355
141CAMK2D0.37455736
142PRKCA0.37219075
143STK380.37048520
144PTK60.36360794
145CSNK1A10.35792342
146TTK0.35721184
147MAP2K30.34761710
148MAP3K120.34713431
149FGFR30.34371436
150BTK0.33415957
151RPS6KA10.33272391
152PRKD20.33268900
153PRKCQ0.32410837
154PIM10.32384855
155MET0.31426925
156AURKB0.31231525
157CSNK1D0.30933494
158MAP3K70.30929995
159ROCK10.29831291
160PRKG10.29716034

Predicted pathways (KEGG)

RankGene SetZ-score
1Sphingolipid metabolism_Homo sapiens_hsa006003.18401961
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.46897829
3Butanoate metabolism_Homo sapiens_hsa006502.44283169
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.40758842
5Tryptophan metabolism_Homo sapiens_hsa003802.19801816
6Arachidonic acid metabolism_Homo sapiens_hsa005902.18138677
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.16184056
8Nitrogen metabolism_Homo sapiens_hsa009102.04646620
9Linoleic acid metabolism_Homo sapiens_hsa005911.86643457
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.86346975
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.85257517
12Oxidative phosphorylation_Homo sapiens_hsa001901.82772026
13Selenocompound metabolism_Homo sapiens_hsa004501.73651700
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.71987434
15Caffeine metabolism_Homo sapiens_hsa002321.68666991
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64964298
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.62723210
18Axon guidance_Homo sapiens_hsa043601.59323498
19Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.54343218
20Fanconi anemia pathway_Homo sapiens_hsa034601.52087677
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.51661979
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.51643668
23Basal cell carcinoma_Homo sapiens_hsa052171.49581638
24Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.49012669
25Peroxisome_Homo sapiens_hsa041461.46287533
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.45516273
27Staphylococcus aureus infection_Homo sapiens_hsa051501.44395669
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.42064103
29Chemical carcinogenesis_Homo sapiens_hsa052041.41769634
30Phototransduction_Homo sapiens_hsa047441.39275149
31Ether lipid metabolism_Homo sapiens_hsa005651.38982925
32NF-kappa B signaling pathway_Homo sapiens_hsa040641.37686984
33Cardiac muscle contraction_Homo sapiens_hsa042601.37423241
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.35037439
35RNA polymerase_Homo sapiens_hsa030201.34603928
36Protein export_Homo sapiens_hsa030601.34573648
37Ribosome_Homo sapiens_hsa030101.32294034
38Parkinsons disease_Homo sapiens_hsa050121.26676132
39Toll-like receptor signaling pathway_Homo sapiens_hsa046201.26655604
40Renin secretion_Homo sapiens_hsa049241.23737652
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23641190
42Retinol metabolism_Homo sapiens_hsa008301.20996937
43Adherens junction_Homo sapiens_hsa045201.20421933
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20021619
45Insulin secretion_Homo sapiens_hsa049111.19816416
46p53 signaling pathway_Homo sapiens_hsa041151.15098873
47Fatty acid elongation_Homo sapiens_hsa000621.14769472
48Pertussis_Homo sapiens_hsa051331.12910765
49Melanoma_Homo sapiens_hsa052181.12888733
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07776261
51GABAergic synapse_Homo sapiens_hsa047271.07592508
52Circadian rhythm_Homo sapiens_hsa047101.07327538
53beta-Alanine metabolism_Homo sapiens_hsa004101.07277247
54Morphine addiction_Homo sapiens_hsa050321.07264988
55Graft-versus-host disease_Homo sapiens_hsa053321.07019691
56SNARE interactions in vesicular transport_Homo sapiens_hsa041301.06905207
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.06821030
58Herpes simplex infection_Homo sapiens_hsa051681.06716273
59Fat digestion and absorption_Homo sapiens_hsa049751.05912911
60Osteoclast differentiation_Homo sapiens_hsa043801.03966190
61Tuberculosis_Homo sapiens_hsa051521.03687663
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02971454
63Rheumatoid arthritis_Homo sapiens_hsa053231.01595241
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.98798902
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.98500829
66Propanoate metabolism_Homo sapiens_hsa006400.98332733
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.97849916
68Basal transcription factors_Homo sapiens_hsa030220.97317930
69TGF-beta signaling pathway_Homo sapiens_hsa043500.97141356
70TNF signaling pathway_Homo sapiens_hsa046680.96579486
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.96401592
72Glutamatergic synapse_Homo sapiens_hsa047240.95740526
73Malaria_Homo sapiens_hsa051440.94731661
74MicroRNAs in cancer_Homo sapiens_hsa052060.94503326
75Mineral absorption_Homo sapiens_hsa049780.93159366
76Circadian entrainment_Homo sapiens_hsa047130.91601298
77Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.91392217
78Hematopoietic cell lineage_Homo sapiens_hsa046400.90658011
79Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.88297659
80Sulfur metabolism_Homo sapiens_hsa009200.88204701
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.88018791
82Fatty acid degradation_Homo sapiens_hsa000710.88010098
83Alzheimers disease_Homo sapiens_hsa050100.87737463
84Huntingtons disease_Homo sapiens_hsa050160.87600736
85Ras signaling pathway_Homo sapiens_hsa040140.86921954
86Nicotine addiction_Homo sapiens_hsa050330.86678462
87Serotonergic synapse_Homo sapiens_hsa047260.86475290
88Phenylalanine metabolism_Homo sapiens_hsa003600.85512923
89Olfactory transduction_Homo sapiens_hsa047400.83562138
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.82882509
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82478385
92Calcium signaling pathway_Homo sapiens_hsa040200.82132387
93Phagosome_Homo sapiens_hsa041450.81831234
94Histidine metabolism_Homo sapiens_hsa003400.81101635
95Glycerolipid metabolism_Homo sapiens_hsa005610.80852571
96Hepatitis C_Homo sapiens_hsa051600.80660550
97Arginine and proline metabolism_Homo sapiens_hsa003300.80617199
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80436665
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79291169
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.79234785
101Toxoplasmosis_Homo sapiens_hsa051450.79125438
102Leishmaniasis_Homo sapiens_hsa051400.78459668
103Vitamin digestion and absorption_Homo sapiens_hsa049770.78418082
104Influenza A_Homo sapiens_hsa051640.78246165
105Sulfur relay system_Homo sapiens_hsa041220.77763022
106Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77056589
107Cocaine addiction_Homo sapiens_hsa050300.76085745
108ABC transporters_Homo sapiens_hsa020100.75808729
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.75038871
110Steroid hormone biosynthesis_Homo sapiens_hsa001400.74549228
111Regulation of autophagy_Homo sapiens_hsa041400.74469611
112Cyanoamino acid metabolism_Homo sapiens_hsa004600.73035399
113Ovarian steroidogenesis_Homo sapiens_hsa049130.72090424
114ECM-receptor interaction_Homo sapiens_hsa045120.69553543
115Homologous recombination_Homo sapiens_hsa034400.69388796
116Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69358999
117Dopaminergic synapse_Homo sapiens_hsa047280.69310303
118Wnt signaling pathway_Homo sapiens_hsa043100.68675029
119Hippo signaling pathway_Homo sapiens_hsa043900.68446538
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.68376465
121Collecting duct acid secretion_Homo sapiens_hsa049660.68274994
122Taste transduction_Homo sapiens_hsa047420.67576278
123Metabolic pathways_Homo sapiens_hsa011000.67199171
124Endometrial cancer_Homo sapiens_hsa052130.66839501
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66533605
126Complement and coagulation cascades_Homo sapiens_hsa046100.66431912
127RNA degradation_Homo sapiens_hsa030180.65709722
128Vascular smooth muscle contraction_Homo sapiens_hsa042700.65704700
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65275447
130GnRH signaling pathway_Homo sapiens_hsa049120.65097198
131Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63623236
132Chemokine signaling pathway_Homo sapiens_hsa040620.61401399
133Glycerophospholipid metabolism_Homo sapiens_hsa005640.61131468
134Salivary secretion_Homo sapiens_hsa049700.60788533
135Autoimmune thyroid disease_Homo sapiens_hsa053200.59754500
136Apoptosis_Homo sapiens_hsa042100.59642300
137Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.59219210
138Tyrosine metabolism_Homo sapiens_hsa003500.58039574
139Amphetamine addiction_Homo sapiens_hsa050310.58005804
140Measles_Homo sapiens_hsa051620.57922397
141Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57793525
142African trypanosomiasis_Homo sapiens_hsa051430.57364506
143Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57088972
144Long-term depression_Homo sapiens_hsa047300.56001455
145Primary immunodeficiency_Homo sapiens_hsa053400.55320936
146Small cell lung cancer_Homo sapiens_hsa052220.55085158
147Rap1 signaling pathway_Homo sapiens_hsa040150.54378167
148One carbon pool by folate_Homo sapiens_hsa006700.54367691
149Allograft rejection_Homo sapiens_hsa053300.54356779
150Arginine biosynthesis_Homo sapiens_hsa002200.53900342
151Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53751405
152Pancreatic secretion_Homo sapiens_hsa049720.53162607
153Leukocyte transendothelial migration_Homo sapiens_hsa046700.52510602
154Prostate cancer_Homo sapiens_hsa052150.50482654
155Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50341077
156Phosphatidylinositol signaling system_Homo sapiens_hsa040700.49812283
157Dorso-ventral axis formation_Homo sapiens_hsa043200.49205666
158Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.48880898
159MAPK signaling pathway_Homo sapiens_hsa040100.47494179
160Cysteine and methionine metabolism_Homo sapiens_hsa002700.47373865
161Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.47321726
162Lysine degradation_Homo sapiens_hsa003100.47010123
163Pathways in cancer_Homo sapiens_hsa052000.46699333
164Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46272345
165Hedgehog signaling pathway_Homo sapiens_hsa043400.45405853
166Other glycan degradation_Homo sapiens_hsa005110.45053199
167Oxytocin signaling pathway_Homo sapiens_hsa049210.44453066
168Bile secretion_Homo sapiens_hsa049760.41464518
169Fatty acid metabolism_Homo sapiens_hsa012120.38843380
170Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38651662

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