CEACAM20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tooth mineralization (GO:0034505)9.05008983
2detection of chemical stimulus involved in sensory perception of smell (GO:0050911)8.86705355
3fat-soluble vitamin biosynthetic process (GO:0042362)7.93998559
4intestinal absorption (GO:0050892)7.54267332
5positive regulation of protein sumoylation (GO:0033235)7.04863064
6negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)7.02662861
7negative regulation of T-helper cell differentiation (GO:0045623)7.02662861
8intestinal cholesterol absorption (GO:0030299)7.00809875
9angiotensin maturation (GO:0002003)6.73311738
10regulation of T-helper 1 cell differentiation (GO:0045625)6.70856656
11regulation of T-helper 2 cell differentiation (GO:0045628)6.60967808
12negative regulation of type 2 immune response (GO:0002829)6.52995031
13activation of protein kinase A activity (GO:0034199)6.38727525
14regulation of RIG-I signaling pathway (GO:0039535)6.20320335
15protein K11-linked deubiquitination (GO:0035871)6.06265374
16bile acid and bile salt transport (GO:0015721)5.95797124
17regulation of guanylate cyclase activity (GO:0031282)5.69838287
18lipoprotein transport (GO:0042953)5.69032608
19negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)5.67915680
20cAMP biosynthetic process (GO:0006171)5.60730601
21sulfate transmembrane transport (GO:1902358)5.58007692
22drug transmembrane transport (GO:0006855)5.57079768
23seminiferous tubule development (GO:0072520)5.55425891
24arachidonic acid secretion (GO:0050482)5.50363017
25icosanoid secretion (GO:0032309)5.50363017
26detection of chemical stimulus involved in sensory perception (GO:0050907)5.48301970
27thrombin receptor signaling pathway (GO:0070493)5.37632787
28positive regulation of RNA splicing (GO:0033120)5.35693058
29regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)5.29767904
30negative regulation of alpha-beta T cell differentiation (GO:0046639)5.27367094
31maintenance of gastrointestinal epithelium (GO:0030277)5.03933188
32epoxygenase P450 pathway (GO:0019373)4.98480583
33negative regulation of keratinocyte proliferation (GO:0010839)4.95643386
34fatty acid derivative transport (GO:1901571)4.93844435
35icosanoid transport (GO:0071715)4.93844435
36diol metabolic process (GO:0034311)4.88664714
37phosphatidylserine acyl-chain remodeling (GO:0036150)4.87358318
38regulation of protein sumoylation (GO:0033233)4.78273694
39sulfate transport (GO:0008272)4.78053505
40bundle of His cell to Purkinje myocyte communication (GO:0086069)4.74748696
41sphingoid metabolic process (GO:0046519)4.74546094
42NADH metabolic process (GO:0006734)4.73319546
43enteric nervous system development (GO:0048484)4.70126982
44phosphatidylglycerol acyl-chain remodeling (GO:0036148)4.68547299
45phosphatidylinositol acyl-chain remodeling (GO:0036149)4.68419329
46drug transport (GO:0015893)4.64571955
47intestinal epithelial cell development (GO:0060576)4.64007705
48regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.59173709
49vitamin transmembrane transport (GO:0035461)4.58565853
50negative regulation of hormone metabolic process (GO:0032351)4.57169869
51negative regulation of hormone biosynthetic process (GO:0032353)4.57169869
52positive regulation of guanylate cyclase activity (GO:0031284)4.49734825
53fructose metabolic process (GO:0006000)4.48040337
54sphingosine metabolic process (GO:0006670)4.46417852
55drug catabolic process (GO:0042737)4.45423670
56regulation of bile acid biosynthetic process (GO:0070857)4.42765974
57desmosome organization (GO:0002934)4.27174656
58actin filament depolymerization (GO:0030042)4.22098484
59negative regulation of homotypic cell-cell adhesion (GO:0034111)4.20455879
60regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.18891069
61endocrine process (GO:0050886)4.18891069
62regulation of systemic arterial blood pressure by hormone (GO:0001990)4.18891069
63piRNA metabolic process (GO:0034587)4.15150732
64cellular response to hepatocyte growth factor stimulus (GO:0035729)4.11822138
65response to hepatocyte growth factor (GO:0035728)4.11822138
66hormone catabolic process (GO:0042447)4.11433758
67detection of bacterium (GO:0016045)4.09428099
68dendritic spine morphogenesis (GO:0060997)4.08675310
69UDP-N-acetylglucosamine metabolic process (GO:0006047)4.08056427
70righting reflex (GO:0060013)4.04744123
71synaptic transmission, dopaminergic (GO:0001963)4.02944103
72cyclic purine nucleotide metabolic process (GO:0052652)4.00784850
73digestive system process (GO:0022600)4.00617711
74diacylglycerol metabolic process (GO:0046339)3.91815825
75heterotypic cell-cell adhesion (GO:0034113)3.90638928
76cyclic nucleotide biosynthetic process (GO:0009190)3.83765679
77vitamin A metabolic process (GO:0006776)3.83546604
78detection of chemical stimulus (GO:0009593)3.82994208
79drug metabolic process (GO:0017144)3.82894213
80cellular zinc ion homeostasis (GO:0006882)3.81372675
81vitamin D metabolic process (GO:0042359)3.81201593
82epithelial structure maintenance (GO:0010669)3.80281774
83positive regulation of T-helper cell differentiation (GO:0045624)3.78867505
84regulation of cellular extravasation (GO:0002691)3.78382903
85positive regulation of T-helper 1 type immune response (GO:0002827)3.77494042
86sulfur compound transport (GO:0072348)3.77227486
87positive regulation of mitochondrial fission (GO:0090141)3.76945118
88regulation of systemic arterial blood pressure (GO:0003073)3.72769009
89positive regulation of Cdc42 GTPase activity (GO:0043089)3.68205721
90striated muscle atrophy (GO:0014891)3.67797393
91endothelial cell differentiation (GO:0045446)3.67143963
92receptor guanylyl cyclase signaling pathway (GO:0007168)3.67086107
93hepatocyte apoptotic process (GO:0097284)3.66742144
94regulation of cGMP biosynthetic process (GO:0030826)3.66168974
95thyroid hormone metabolic process (GO:0042403)3.64200286
96positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.55328561
97leukotriene metabolic process (GO:0006691)3.54935523
98peptide hormone processing (GO:0016486)3.54641784
99positive regulation of megakaryocyte differentiation (GO:0045654)3.53491741
100alkaloid metabolic process (GO:0009820)3.52744507
101vitamin biosynthetic process (GO:0009110)3.49571923
102calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.48269025
103detection of other organism (GO:0098543)3.47668962
104regulation of glucocorticoid metabolic process (GO:0031943)3.47559666
105phosphatidylcholine acyl-chain remodeling (GO:0036151)3.47404407
106positive regulation of glycoprotein biosynthetic process (GO:0010560)3.42759811
107negative regulation of steroid biosynthetic process (GO:0010894)3.41972113
108very-low-density lipoprotein particle assembly (GO:0034379)3.41523114
109protein kinase C signaling (GO:0070528)3.40056031
110regulation of meiosis (GO:0040020)3.39948939
111regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.37407905
112phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.35519182
113phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.34770091
114regulation of triglyceride catabolic process (GO:0010896)3.32993285
115cellular glucuronidation (GO:0052695)3.32724184
116water transport (GO:0006833)3.31403069
117regulation of keratinocyte proliferation (GO:0010837)3.29194287
118tight junction assembly (GO:0070830)3.28947854
119regulation of meiosis I (GO:0060631)3.25387875
120regulation of Cdc42 GTPase activity (GO:0043088)3.25293465
121modified amino acid transport (GO:0072337)3.25130546
122oocyte maturation (GO:0001556)3.25024078
123negative regulation of alpha-beta T cell activation (GO:0046636)3.23203262
124regulation of viral release from host cell (GO:1902186)3.22205832
125notochord development (GO:0030903)3.21718094
126uronic acid metabolic process (GO:0006063)3.21702254
127glucuronate metabolic process (GO:0019585)3.21702254
128adhesion of symbiont to host (GO:0044406)3.20509886
129negative regulation of smooth muscle cell differentiation (GO:0051151)3.19621520
130parturition (GO:0007567)3.19327383
131positive regulation of protein targeting to membrane (GO:0090314)3.18412625
132positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.18279927
133regulation of proton transport (GO:0010155)3.17396214
134bicarbonate transport (GO:0015701)3.16137980
135negative regulation of steroid metabolic process (GO:0045939)3.15968231
136leukotriene biosynthetic process (GO:0019370)3.12699662
137female gamete generation (GO:0007292)3.11973822
138renal system process involved in regulation of blood volume (GO:0001977)3.11426223
139skeletal muscle adaptation (GO:0043501)3.10715413
140purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.10475999
1413-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.10475999
142muscle atrophy (GO:0014889)3.10087896
143negative regulation of cell-cell adhesion (GO:0022408)3.08300663
144negative regulation of protein tyrosine kinase activity (GO:0061099)3.08070882
145antibacterial humoral response (GO:0019731)3.07540674
146glycerophospholipid catabolic process (GO:0046475)3.06506383
147embryonic digestive tract morphogenesis (GO:0048557)3.06367563
148O-glycan processing (GO:0016266)3.06067891
149urea cycle (GO:0000050)3.05194631
150regulation of cGMP metabolic process (GO:0030823)3.05129819
151vitamin transport (GO:0051180)3.02811909
152regulation of histone H3-K27 methylation (GO:0061085)3.02253114
153transepithelial transport (GO:0070633)3.01902983
154regulation of protein glycosylation (GO:0060049)3.00871579
155digestion (GO:0007586)2.99683738
156plasma lipoprotein particle assembly (GO:0034377)2.98559368
157antimicrobial humoral response (GO:0019730)2.98462918
158negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.98003607
159glutathione biosynthetic process (GO:0006750)2.97955760
160hyaluronan catabolic process (GO:0030214)2.97651608
161fluid transport (GO:0042044)2.95400422
162cytoskeletal anchoring at plasma membrane (GO:0007016)2.93239660
163urea metabolic process (GO:0019627)2.93231955
164cGMP-mediated signaling (GO:0019934)2.92808761
165zinc ion homeostasis (GO:0055069)2.92681660
166regulation of vitamin metabolic process (GO:0030656)2.91540286
167DNA methylation involved in gamete generation (GO:0043046)2.90294437
168regulation of transforming growth factor beta2 production (GO:0032909)2.90262523
169meiotic chromosome segregation (GO:0045132)2.89345462
170virion attachment to host cell (GO:0019062)2.88124540
171adhesion of symbiont to host cell (GO:0044650)2.88124540
172phosphatidylcholine biosynthetic process (GO:0006656)2.87273428
173male meiosis (GO:0007140)2.86649394
174mitotic metaphase plate congression (GO:0007080)2.86021488
175DNA damage induced protein phosphorylation (GO:0006975)2.84996260
176sperm capacitation (GO:0048240)2.83262871
177keratinocyte development (GO:0003334)2.81468915
178drinking behavior (GO:0042756)2.78607856
179flavonoid metabolic process (GO:0009812)2.78201803
180myoblast migration (GO:0051451)2.75586027
181columnar/cuboidal epithelial cell development (GO:0002066)2.75482150
182neurotransmitter biosynthetic process (GO:0042136)2.74905476
183polyol biosynthetic process (GO:0046173)2.72680461
184regulation of meiotic cell cycle (GO:0051445)2.71330328
185regulation of female gonad development (GO:2000194)2.67624053
186keratinocyte proliferation (GO:0043616)2.65598892
187female gonad development (GO:0008585)2.63895856

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse7.37961706
2GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse5.40923317
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.39376824
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.41577863
5SMAD_19615063_ChIP-ChIP_OVARY_Human3.20615602
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.92705697
7CDX2_20551321_ChIP-Seq_CACO-2_Human2.69723752
8AR_21572438_ChIP-Seq_LNCaP_Human2.66472056
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.64840419
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.58231895
11* KAP1_22055183_ChIP-Seq_ESCs_Mouse2.48124034
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.29050531
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.26124309
14CDX2_19796622_ChIP-Seq_MESCs_Mouse2.19543548
15RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.13451582
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.05715502
17TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.03139931
18VDR_22108803_ChIP-Seq_LS180_Human1.99216789
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.94503568
20TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93010655
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.91113805
22GATA1_26923725_Chip-Seq_HPCs_Mouse1.90438377
23NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.85341277
24GATA1_19941826_ChIP-Seq_K562_Human1.78761664
25SOX2_20726797_ChIP-Seq_SW620_Human1.75635646
26GATA4_25053715_ChIP-Seq_YYC3_Human1.69908372
27PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64401178
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.63589742
29AR_21909140_ChIP-Seq_LNCAP_Human1.62826280
30SUZ12_27294783_Chip-Seq_NPCs_Mouse1.61695729
31RXR_22108803_ChIP-Seq_LS180_Human1.61666140
32BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.60184143
33SOX2_27498859_Chip-Seq_STOMACH_Mouse1.57795192
34CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57523873
35EGR1_19032775_ChIP-ChIP_M12_Human1.57487757
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.56863558
37TCF4_18268006_ChIP-ChIP_LS174T_Human1.56223689
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56215178
39LXR_22158963_ChIP-Seq_LIVER_Mouse1.55371110
40YY1_22570637_ChIP-Seq_MALME-3M_Human1.55237842
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.55114973
42RXR_22158963_ChIP-Seq_LIVER_Mouse1.54081688
43FOXM1_26456572_ChIP-Seq_MCF-7_Human1.53066441
44ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49653445
45DROSHA_22980978_ChIP-Seq_HELA_Human1.45931819
46CDX2_22108803_ChIP-Seq_LS180_Human1.45845612
47ESR1_21235772_ChIP-Seq_MCF-7_Human1.44106823
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.43652712
49BCAT_22108803_ChIP-Seq_LS180_Human1.43299011
50TP53_16413492_ChIP-PET_HCT116_Human1.41768776
51AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.41119533
52STAT1_17558387_ChIP-Seq_HELA_Human1.40319158
53SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40112549
54PPARA_22158963_ChIP-Seq_LIVER_Mouse1.40026405
55GATA6_25053715_ChIP-Seq_YYC3_Human1.37713386
56EZH2_27294783_Chip-Seq_NPCs_Mouse1.37158399
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.36779238
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36310784
59SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.35778483
60SMAD3_21741376_ChIP-Seq_HESCs_Human1.34459382
61TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34337604
62PPAR_26484153_Chip-Seq_NCI-H1993_Human1.34199281
63ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.34010133
64AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.32453216
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29243747
66KLF5_25053715_ChIP-Seq_YYC3_Human1.27895554
67PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.27542396
68EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26882120
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25250882
70CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25239132
71PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.25146840
72TP63_19390658_ChIP-ChIP_HaCaT_Human1.24338972
73ESR1_20079471_ChIP-ChIP_T-47D_Human1.24211642
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24005348
75LXR_22292898_ChIP-Seq_THP-1_Human1.23008248
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21862348
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.20883209
78PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.20436158
79STAT3_18555785_Chip-Seq_ESCs_Mouse1.20214797
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19787878
81KDM2B_26808549_Chip-Seq_REH_Human1.18988188
82GATA2_19941826_ChIP-Seq_K562_Human1.18926558
83CTCF_27219007_Chip-Seq_Bcells_Human1.18790837
84HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.17618398
85SUZ12_18555785_Chip-Seq_ESCs_Mouse1.16553735
86CMYC_18555785_Chip-Seq_ESCs_Mouse1.15681326
87NANOG_20526341_ChIP-Seq_ESCs_Human1.15606760
88NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.15353687
89CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.14558800
90IGF1R_20145208_ChIP-Seq_DFB_Human1.14086465
91ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.13904315
92P53_22387025_ChIP-Seq_ESCs_Mouse1.12887368
93ESRRB_18555785_Chip-Seq_ESCs_Mouse1.12778960
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.09553954
95KLF4_18555785_Chip-Seq_ESCs_Mouse1.08515417
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.07949513
97CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07676204
98RNF2_27304074_Chip-Seq_NSC_Mouse1.07241718
99CJUN_26792858_Chip-Seq_BT549_Human1.06159177
100ESR2_21235772_ChIP-Seq_MCF-7_Human1.06150818
101TBL1_22424771_ChIP-Seq_293T_Human1.05229764
102MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04470217
103OCT4_18555785_Chip-Seq_ESCs_Mouse1.04052295
104* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.02800480
105CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.02254066
106GBX2_23144817_ChIP-Seq_PC3_Human1.01218468
107LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00228462
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.99296868
109TAL1_26923725_Chip-Seq_HPCs_Mouse0.98906511
110P300_18555785_Chip-Seq_ESCs_Mouse0.98762954
111SOX2_18555785_Chip-Seq_ESCs_Mouse0.98486996
112SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.96553629
113BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96165935
114EZH2_22144423_ChIP-Seq_EOC_Human0.96090739
115BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.95332991
116SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.95311320
117OCT4_21477851_ChIP-Seq_ESCs_Mouse0.95215272
118TCF3_18692474_ChIP-Seq_MESCs_Mouse0.95207750
119JARID2_20075857_ChIP-Seq_MESCs_Mouse0.94748046
120SMAD3_21741376_ChIP-Seq_EPCs_Human0.94671149
121FOXA1_25552417_ChIP-Seq_VCAP_Human0.94087410
122FUS_26573619_Chip-Seq_HEK293_Human0.93661718
123CTBP1_25329375_ChIP-Seq_LNCAP_Human0.93381873
124NMYC_18555785_Chip-Seq_ESCs_Mouse0.93055950
125MTF2_20144788_ChIP-Seq_MESCs_Mouse0.92755868
126CTCF_18555785_Chip-Seq_ESCs_Mouse0.92750833
127GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.92175667
128STAT3_23295773_ChIP-Seq_U87_Human0.92171578
129ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92098965
130ZFX_18555785_Chip-Seq_ESCs_Mouse0.92038712
131PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.92015843
132CRX_20693478_ChIP-Seq_RETINA_Mouse0.91975533
133CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91534458
134SA1_27219007_Chip-Seq_Bcells_Human0.91448293
135VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.91345681
136RUNX1_27514584_Chip-Seq_MCF-7_Human0.90958870
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.90700149
138FOXO3_23340844_ChIP-Seq_DLD1_Human0.90440884
139HNFA_21074721_ChIP-Seq_CACO-2_Human0.90217082
140SMAD4_21799915_ChIP-Seq_A2780_Human0.90210492
141GATA1_22025678_ChIP-Seq_K562_Human0.90100972
142POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89608264
143TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89608264
144GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.89036321
145RUNX1_27457419_Chip-Seq_LIVER_Mouse0.88860978
146FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88392366
147STAT1_20625510_ChIP-Seq_HELA_Human0.88239687
148TRIM28_21343339_ChIP-Seq_HEK293_Human0.88223770
149TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88106303
150FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88002699
151SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.87380601
152GATA6_21074721_ChIP-Seq_CACO-2_Human0.86798064
153SUZ12_27294783_Chip-Seq_ESCs_Mouse0.85430575
154SMAD4_21741376_ChIP-Seq_HESCs_Human0.85247403
155HIF1A_21447827_ChIP-Seq_MCF-7_Human0.84853027
156SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.84393480
157NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.84369270
158CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.84282408
159PHF8_20622853_ChIP-Seq_HELA_Human0.83245526
160EZH2_27294783_Chip-Seq_ESCs_Mouse0.82604155
161TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.82454259
162EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.78834042
163PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.78481378
164ARNT_22903824_ChIP-Seq_MCF-7_Human0.78111812
165TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.77620975
166GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.76426749
167RNF2_27304074_Chip-Seq_ESCs_Mouse0.75813269
168TCF4_22108803_ChIP-Seq_LS180_Human0.74129966
169SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.73654452
170CREB1_26743006_Chip-Seq_LNCaP_Human0.73334321
171JARID2_20064375_ChIP-Seq_MESCs_Mouse0.73184594

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle7.50325635
2MP0005360_urolithiasis6.11298015
3MP0008961_abnormal_basal_metabolism5.20743939
4MP0004264_abnormal_extraembryonic_tissu4.22641121
5MP0005451_abnormal_body_composition3.99399162
6MP0002102_abnormal_ear_morphology3.47863961
7MP0001666_abnormal_nutrient_absorption3.44295029
8MP0003718_maternal_effect3.43632586
9MP0000462_abnormal_digestive_system3.43294918
10MP0005377_hearing/vestibular/ear_phenot2.68153691
11MP0003878_abnormal_ear_physiology2.68153691
12MP0003693_abnormal_embryo_hatching2.67018519
13MP0003866_abnormal_defecation2.63881979
14MP0009379_abnormal_foot_pigmentation2.34407037
15MP0004130_abnormal_muscle_cell2.27737999
16MP0003315_abnormal_perineum_morphology2.23689916
17MP0005448_abnormal_energy_balance2.20426297
18MP0002796_impaired_skin_barrier2.17908523
19MP0000490_abnormal_crypts_of2.15383592
20MP0005310_abnormal_salivary_gland2.13324155
21MP0003646_muscle_fatigue2.07109271
22MP0000538_abnormal_urinary_bladder1.97325601
23MP0003183_abnormal_peptide_metabolism1.92820898
24MP0000427_abnormal_hair_cycle1.91349185
25MP0005381_digestive/alimentary_phenotyp1.91198241
26MP0002822_catalepsy1.89796829
27MP0005085_abnormal_gallbladder_physiolo1.86799719
28MP0010678_abnormal_skin_adnexa1.84359759
29MP0001663_abnormal_digestive_system1.71402868
30MP0002876_abnormal_thyroid_physiology1.67566447
31MP0005332_abnormal_amino_acid1.67047676
32MP0003329_amyloid_beta_deposits1.63719899
33MP0003787_abnormal_imprinting1.60322011
34MP0008877_abnormal_DNA_methylation1.60042419
35MP0010155_abnormal_intestine_physiology1.55087004
36MP0001664_abnormal_digestion1.54212741
37MP0002249_abnormal_larynx_morphology1.47168000
38MP0000477_abnormal_intestine_morphology1.47120933
39MP0003806_abnormal_nucleotide_metabolis1.46803223
40MP0005084_abnormal_gallbladder_morpholo1.46537356
41MP0005409_darkened_coat_color1.41789464
42MP0008875_abnormal_xenobiotic_pharmacok1.39339147
43MP0004147_increased_porphyrin_level1.38607523
44MP0005501_abnormal_skin_physiology1.34772835
45MP0000579_abnormal_nail_morphology1.34395695
46MP0004272_abnormal_basement_membrane1.34246383
47MP0003879_abnormal_hair_cell1.33954055
48MP0002136_abnormal_kidney_physiology1.29687496
49MP0003252_abnormal_bile_duct1.29334423
50MP0009643_abnormal_urine_homeostasis1.28804705
51MP0002653_abnormal_ependyma_morphology1.27982464
52MP0009764_decreased_sensitivity_to1.25198363
53MP0005166_decreased_susceptibility_to1.21977678
54MP0010352_gastrointestinal_tract_polyps1.21232806
55MP0000604_amyloidosis1.20613920
56MP0005395_other_phenotype1.19503251
57MP0001764_abnormal_homeostasis1.16140836
58MP0003453_abnormal_keratinocyte_physiol1.16079553
59MP0001873_stomach_inflammation1.15357995
60MP0005165_increased_susceptibility_to1.15222768
61MP0000465_gastrointestinal_hemorrhage1.15037054
62MP0001216_abnormal_epidermal_layer1.13486131
63MP0000609_abnormal_liver_physiology1.12890220
64MP0005636_abnormal_mineral_homeostasis1.07433765
65MP0003937_abnormal_limbs/digits/tail_de1.07147738
66MP0008004_abnormal_stomach_pH1.05402545
67MP0004782_abnormal_surfactant_physiolog1.04175066
68MP0001765_abnormal_ion_homeostasis1.03415907
69MP0001849_ear_inflammation1.03064285
70MP0001119_abnormal_female_reproductive1.02409104
71MP0000470_abnormal_stomach_morphology1.01558607
72MP0001270_distended_abdomen1.00995259
73MP0008469_abnormal_protein_level1.00884076
74MP0004858_abnormal_nervous_system1.00260419
75MP0004957_abnormal_blastocyst_morpholog0.96851305
76MP0000566_synostosis0.96235182
77MP0004185_abnormal_adipocyte_glucose0.94657893
78MP0003950_abnormal_plasma_membrane0.94507757
79MP0006292_abnormal_olfactory_placode0.93935318
80MP0005670_abnormal_white_adipose0.93419448
81MP0001845_abnormal_inflammatory_respons0.92587618
82MP0002118_abnormal_lipid_homeostasis0.92036059
83MP0005365_abnormal_bile_salt0.91184106
84MP0000383_abnormal_hair_follicle0.89294931
85MP0010386_abnormal_urinary_bladder0.88046679
86MP0003699_abnormal_female_reproductive0.87849930
87MP0010329_abnormal_lipoprotein_level0.86743603
88MP0002751_abnormal_autonomic_nervous0.85913238
89MP0002098_abnormal_vibrissa_morphology0.85790981
90MP0003638_abnormal_response/metabolism_0.85769351
91MP0004947_skin_inflammation0.85617883
92MP0002277_abnormal_respiratory_mucosa0.85482189
93MP0001188_hyperpigmentation0.81348671
94MP0009642_abnormal_blood_homeostasis0.80765109
95MP0000377_abnormal_hair_follicle0.80313936
96MP0003941_abnormal_skin_development0.79449415
97MP0004270_analgesia0.78504030
98MP0002060_abnormal_skin_morphology0.77845006
99MP0003938_abnormal_ear_development0.77386392
100MP0002078_abnormal_glucose_homeostasis0.77160913
101MP0004019_abnormal_vitamin_homeostasis0.77152018
102MP0000762_abnormal_tongue_morphology0.77090373
103MP0001756_abnormal_urination0.76741834
104MP0005319_abnormal_enzyme/_coenzyme0.75548813
105MP0003953_abnormal_hormone_level0.75102607
106MP0009250_abnormal_appendicular_skeleto0.74350741
107MP0003111_abnormal_nucleus_morphology0.73044164
108MP0002139_abnormal_hepatobiliary_system0.72686238
109MP0006072_abnormal_retinal_apoptosis0.71436129
110MP0000653_abnormal_sex_gland0.70839844
111MP0005334_abnormal_fat_pad0.69373487
112MP0001963_abnormal_hearing_physiology0.69193993
113MP0002998_abnormal_bone_remodeling0.66730496
114MP0004133_heterotaxia0.66611179
115MP0005535_abnormal_body_temperature0.66135272
116MP0005408_hypopigmentation0.65195299
117MP0002233_abnormal_nose_morphology0.65072989
118MP0002928_abnormal_bile_duct0.63898261
119MP0000230_abnormal_systemic_arterial0.63624862
120MP0010771_integument_phenotype0.63531843
121MP0001958_emphysema0.63249315
122MP0001790_abnormal_immune_system0.63053062
123MP0005387_immune_system_phenotype0.63053062
124MP0001929_abnormal_gametogenesis0.61650274
125MP0004484_altered_response_of0.61228838
126MP0002396_abnormal_hematopoietic_system0.60733673
127MP0000537_abnormal_urethra_morphology0.60493797
128MP0009785_altered_susceptibility_to0.60210786
129MP0003868_abnormal_feces_composition0.58140324
130MP0004381_abnormal_hair_follicle0.57522035
131MP0001501_abnormal_sleep_pattern0.57204579
132MP0000249_abnormal_blood_vessel0.56688726
133MP0001835_abnormal_antigen_presentation0.56011375
134MP0000432_abnormal_head_morphology0.55963235
135MP0001533_abnormal_skeleton_physiology0.55875974
136MP0002909_abnormal_adrenal_gland0.54967119
137MP0001905_abnormal_dopamine_level0.54788031
138MP0000026_abnormal_inner_ear0.54353944
139MP0001800_abnormal_humoral_immune0.54114353
140MP0001346_abnormal_lacrimal_gland0.52944716
141MP0004043_abnormal_pH_regulation0.52880272
142MP0003755_abnormal_palate_morphology0.52851048
143MP0005167_abnormal_blood-brain_barrier0.51358660
144MP0005367_renal/urinary_system_phenotyp0.50895386
145MP0000516_abnormal_urinary_system0.50895386
146MP0001243_abnormal_dermal_layer0.50370149
147MP0001485_abnormal_pinna_reflex0.49193117
148MP0005584_abnormal_enzyme/coenzyme_acti0.48599402
149MP0000678_abnormal_parathyroid_gland0.48510934
150MP0002210_abnormal_sex_determination0.47973958
151MP0000613_abnormal_salivary_gland0.47701377
152MP0009840_abnormal_foam_cell0.47593509
153MP0002971_abnormal_brown_adipose0.46413780

Predicted human phenotypes

RankGene SetZ-score
1Amelogenesis imperfecta (HP:0000705)6.43894924
2Overgrowth (HP:0001548)6.24746858
3Widely patent fontanelles and sutures (HP:0004492)6.03643679
4Abnormality of calcium-phosphate metabolism (HP:0100530)5.76207175
5Thin bony cortex (HP:0002753)5.23352125
6Osteomalacia (HP:0002749)5.11708175
7Enlarged epiphyses (HP:0010580)5.04854307
8Delayed epiphyseal ossification (HP:0002663)5.02505288
9Hypobetalipoproteinemia (HP:0003563)4.90130236
10Ileus (HP:0002595)4.79244883
11Right ventricular cardiomyopathy (HP:0011663)4.69041637
12Abnormality of dental color (HP:0011073)4.31545708
13Progressive hearing impairment (HP:0001730)4.30788777
14Glycosuria (HP:0003076)4.28887426
15Abnormality of urine glucose concentration (HP:0011016)4.28887426
16Abnormality of the dental pulp (HP:0006479)4.21617842
17Abnormal urine output (HP:0012590)4.17185466
18Abnormality of renal resorption (HP:0011038)4.11540836
19Male infertility (HP:0003251)4.02220343
20Abnormality of the costochondral junction (HP:0000919)3.91924485
21Malnutrition (HP:0004395)3.87546170
22Abnormality of renal excretion (HP:0011036)3.85786052
23Breast hypoplasia (HP:0003187)3.85038782
24Villous atrophy (HP:0011473)3.82004365
25Abnormality of small intestinal villus morphology (HP:0011472)3.82004365
26Lip pit (HP:0100267)3.69983617
27Confusion (HP:0001289)3.68668395
28Abnormality of glutamine family amino acid metabolism (HP:0010902)3.59743136
29Polyuria (HP:0000103)3.55579045
30Hyperphosphaturia (HP:0003109)3.45153928
31Wide cranial sutures (HP:0010537)3.43560672
32Metaphyseal irregularity (HP:0003025)3.35408114
33Abnormal urine phosphate concentration (HP:0012599)3.33298091
34Nephrolithiasis (HP:0000787)3.28844050
35Hyperglycinuria (HP:0003108)3.23707932
36Systemic lupus erythematosus (HP:0002725)3.18595551
37Abnormality of vitamin metabolism (HP:0100508)3.11580787
38Flat capital femoral epiphysis (HP:0003370)3.10694815
39Conjugated hyperbilirubinemia (HP:0002908)3.06294788
40Facial shape deformation (HP:0011334)3.02902876
41Potter facies (HP:0002009)3.02902876
42Acanthocytosis (HP:0001927)2.98781917
43IgM deficiency (HP:0002850)2.95649123
44Tibial bowing (HP:0002982)2.95388520
45Shawl scrotum (HP:0000049)2.94315771
46Cupped ribs (HP:0000887)2.90064277
47Abnormality of the 1st metacarpal (HP:0010009)2.85819894
48Hyperactive renin-angiotensin system (HP:0000841)2.84694651
49Abnormality of the fingertips (HP:0001211)2.83654060
50Abnormality of proline metabolism (HP:0010907)2.77645878
51Hydroxyprolinuria (HP:0003080)2.77645878
52Nausea (HP:0002018)2.77240165
53Abnormality of the phalanges of the hallux (HP:0010057)2.76648647
54Prostate neoplasm (HP:0100787)2.75472227
55Decreased circulating renin level (HP:0003351)2.74616938
56Abnormality of glycine metabolism (HP:0010895)2.72587743
57Abnormality of serine family amino acid metabolism (HP:0010894)2.72587743
58Flat acetabular roof (HP:0003180)2.71432572
59Chronic diarrhea (HP:0002028)2.70948425
60Petechiae (HP:0000967)2.62062914
61Xanthomatosis (HP:0000991)2.59661471
62Increased purine levels (HP:0004368)2.58954642
63Hyperuricemia (HP:0002149)2.58954642
64Round ear (HP:0100830)2.58708435
65Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.55261024
66Congenital sensorineural hearing impairment (HP:0008527)2.54714543
67Syncope (HP:0001279)2.53113989
68Abnormality of the distal phalanx of the thumb (HP:0009617)2.49462696
69Proximal tubulopathy (HP:0000114)2.48272002
70Progressive sensorineural hearing impairment (HP:0000408)2.47910918
71Aplasia cutis congenita (HP:0001057)2.47755710
72Metabolic alkalosis (HP:0200114)2.46681873
73Colitis (HP:0002583)2.46247012
74Dehydration (HP:0001944)2.43536424
75Alkalosis (HP:0001948)2.42908627
76Symphalangism affecting the phalanges of the hand (HP:0009773)2.42485529
77Steatorrhea (HP:0002570)2.41901996
78Abnormality of monocarboxylic acid metabolism (HP:0010996)2.39648565
79Curly hair (HP:0002212)2.38877054
80Pili torti (HP:0003777)2.38195300
81Abnormality of purine metabolism (HP:0004352)2.34169159
82Toxemia of pregnancy (HP:0100603)2.32888135
83Chronic bronchitis (HP:0004469)2.32026249
84Esophageal varix (HP:0002040)2.29407807
85Milia (HP:0001056)2.27435274
86Abnormality of renin-angiotensin system (HP:0000847)2.26892988
87Hypolipoproteinemia (HP:0010981)2.26684658
88Abnormality of chloride homeostasis (HP:0011422)2.25631153
89Aplasia/Hypoplasia of the breasts (HP:0010311)2.24852062
90Renal tubular dysfunction (HP:0000124)2.23625075
91Ureteral stenosis (HP:0000071)2.21892273
92Abnormal tarsal ossification (HP:0008369)2.21856686
93Abnormality of the gastric mucosa (HP:0004295)2.20367697
94Flat occiput (HP:0005469)2.18504151
95Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.15670640
96Abnormal biliary tract morphology (HP:0012440)2.15221185
97Chromsome breakage (HP:0040012)2.15172321
98Hyperparathyroidism (HP:0000843)2.15146160
99Chondrocalcinosis (HP:0000934)2.13233524
100Lipoatrophy (HP:0100578)2.13074711
101Megaloblastic anemia (HP:0001889)2.12977465
102Abnormality of the vitamin B12 metabolism (HP:0004341)2.12755758
103Fat malabsorption (HP:0002630)2.11651386
104Ureteral obstruction (HP:0006000)2.11103900
105Rickets (HP:0002748)2.09759570
106Abnormality of the fibula (HP:0002991)2.09436017
107Onycholysis (HP:0001806)2.08786497
108Abnormal trabecular bone morphology (HP:0100671)2.08187899
109Biliary tract neoplasm (HP:0100574)2.07493708
110Abnormality of Sharpey fibers (HP:0100685)2.05299630
111Femoral bowing (HP:0002980)2.05213622
112Capillary hemangiomas (HP:0005306)2.04851483
113Hypercalciuria (HP:0002150)2.04779271
114Focal segmental glomerulosclerosis (HP:0000097)2.03547440
115Posterior subcapsular cataract (HP:0007787)2.03504083
116Abnormality of the proximal phalanges of the hand (HP:0009834)2.02961257
117Abnormality of nucleobase metabolism (HP:0010932)2.01703724
118Patellar aplasia (HP:0006443)2.00964410
119Hypoplastic iliac wings (HP:0002866)2.00601497
120Pustule (HP:0200039)1.99791416
121Breast aplasia (HP:0100783)1.99486989
122Abnormality of vitamin B metabolism (HP:0004340)1.96081187
123Eczematoid dermatitis (HP:0000976)1.95786265
124Abnormality of aspartate family amino acid metabolism (HP:0010899)1.95704603
125Hypotension (HP:0002615)1.95474544
126Hypoplasia of dental enamel (HP:0006297)1.95438940
127Genu varum (HP:0002970)1.94821957
128Parakeratosis (HP:0001036)1.94593085
129Ectropion (HP:0000656)1.93231699
130Abdominal distention (HP:0003270)1.92437820
131Chromosomal breakage induced by crosslinking agents (HP:0003221)1.92350944
132Abnormal delayed hypersensitivity skin test (HP:0002963)1.92026027
133Dilated cardiomyopathy (HP:0001644)1.91796158
134Birth length less than 3rd percentile (HP:0003561)1.91349160
135Cone-rod dystrophy (HP:0000548)1.91251087
136Plantar hyperkeratosis (HP:0007556)1.91217992
137Autoimmune thrombocytopenia (HP:0001973)1.90246892
138Nephrocalcinosis (HP:0000121)1.89429776
139Aplasia/Hypoplasia of the patella (HP:0006498)1.88803496
140Sparse lateral eyebrow (HP:0005338)1.88624092
141Short 1st metacarpal (HP:0010034)1.86879731
142Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.86879731
143Poikilocytosis (HP:0004447)1.86631523
144Metabolic acidosis (HP:0001942)1.86173910
145Tongue fasciculations (HP:0001308)1.85623256
146Gout (HP:0001997)1.85333446
147Microretrognathia (HP:0000308)1.84635980
148Inflammation of the large intestine (HP:0002037)1.84388430
149Hemorrhage of the eye (HP:0011885)1.84003666
150Hypophosphatemia (HP:0002148)1.83227922
151Mildly elevated creatine phosphokinase (HP:0008180)1.83125876
152Abnormality of magnesium homeostasis (HP:0004921)1.78445244
153Fragile nails (HP:0001808)1.77890057
154Hyperammonemia (HP:0001987)1.77694499
155Hyperphosphatemia (HP:0002905)1.76748507
156Aplasia/hypoplasia of the femur (HP:0005613)1.76442834
157Intestinal fistula (HP:0100819)1.75021362
158Short phalanx of the thumb (HP:0009660)1.74839792
159Sudden cardiac death (HP:0001645)1.74677389
160Facial hemangioma (HP:0000329)1.74122084
161Short femoral neck (HP:0100864)1.73653589
162Epidermoid cyst (HP:0200040)1.72556422
163Papillary thyroid carcinoma (HP:0002895)1.71749452
164Short thumb (HP:0009778)1.71317693
165Ventricular tachycardia (HP:0004756)1.70985823
166Breech presentation (HP:0001623)1.70410926
167Pigmentary retinal degeneration (HP:0001146)1.70327519
168Abnormality of the preputium (HP:0100587)1.70126282
169Abnormality of carpal bone ossification (HP:0006257)1.69725273
170Pancreatitis (HP:0001733)1.69658735
171Glomerulonephritis (HP:0000099)1.69502987
172Abnormality of the 2nd finger (HP:0004100)1.69228299

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.99546864
2FRK3.82629161
3MAP3K63.40626688
4ARAF3.13289807
5MAP3K133.05667577
6KSR23.01277689
7MAP3K92.95853021
8PIK3CA2.86602241
9LATS12.85582945
10MST42.65556162
11MST1R2.61582683
12BRAF2.50157718
13TAOK12.42666987
14ERBB42.42014745
15CDC42BPA2.40046722
16ERN12.33662084
17TTK2.27880554
18MUSK2.26515544
19STK242.23658660
20RIPK12.19310371
21TAOK32.14315387
22PLK42.10274766
23DMPK2.08943827
24NTRK210.2918791
25STK38L1.96078337
26PINK11.95856413
27RAF11.93793114
28AKT31.93225744
29MAP3K101.92552709
30STK31.75001384
31NUAK11.66455413
32LATS21.65072665
33PRKG21.45688225
34MAP2K21.44674634
35STK391.42533216
36LMTK21.35087875
37RIPK41.33939877
38NLK1.29215172
39EPHA21.24986455
40NME11.24460631
41OBSCN1.22468007
42OXSR11.20429805
43MOS1.20197995
44MELK1.19146347
45CDK31.19044567
46CDK81.16264401
47PRKAA21.15057706
48GRK61.11388357
49STK101.08160068
50PDK21.07759018
51CDK91.06923058
52CHEK21.03692080
53MAP3K81.01139157
54PRKCI1.00612727
55MAPKAPK30.95644315
56EEF2K0.95322186
57DDR20.93719782
58FGFR40.92216884
59MAP2K10.91468982
60EPHA30.90597926
61EPHB20.87422022
62HIPK20.85197117
63MAP3K120.82532378
64PTK20.77251742
65KSR10.75074815
66PRKACG0.75016283
67TNIK0.74511024
68AURKB0.73871754
69TESK20.71301880
70CDC70.70949716
71EPHB10.70016223
72IKBKE0.69912789
73SRC0.69810948
74PRKCQ0.68062913
75MATK0.67535065
76PRKAA10.63980062
77DYRK20.63723378
78BLK0.61332976
79BMPR20.59849517
80SYK0.58871854
81MAP3K20.57116923
82TYK20.56759370
83ABL20.54449367
84MAP2K70.54332884
85MAP3K40.54141474
86ROCK20.53620434
87ROCK10.51928942
88MAP3K10.51098693
89CHUK0.50291638
90TRPM70.50211003
91INSRR0.48248073
92YES10.48207031
93MAPK110.46597862
94CAMK2D0.45666904
95MARK30.44810879
96MAP2K60.41828831
97FGFR30.41194969
98TBK10.40143498
99GRK10.38669249
100MAPK130.38493294
101SGK20.38381240
102PLK10.38372913
103MYLK0.38118982
104PRKACA0.37950699
105FGFR10.37480939
106MAP3K140.36442774
107CAMK2A0.35810543
108PRPF4B0.35639604
109CASK0.35020885
110BTK0.34633119
111EIF2AK20.33375691
112FYN0.33172779
113FGR0.32701777
114EPHA40.32451437
115MET0.31856558
116MAP3K50.31587361
117PIM10.31463825
118TIE10.30709123
119STK110.29769770
120MAP3K30.29504781
121PRKCD0.28528219
122PDPK10.28419322
123PTK60.28348526
124PDK10.27854154
125PIK3CG0.27471704
126CAMK2G0.27348736
127PRKD20.26975836
128FER0.26532097
129ADRBK20.26517806
130SGK30.25527683
131ITK0.25009396
132ATM0.24550400
133CDK70.24277089
134ERBB20.24176423
135LYN0.21362481
136PRKCA0.21349869
137CAMK2B0.21045164
138ABL10.20690692
139PRKG10.20466808
140MAP2K40.20249222
141BMPR1B0.20052208
142RET0.19218319
143PAK60.18955193
144ACVR1B0.18813986
145MAPK150.17761522
146KIT0.17677553
147PRKCB0.17619485
148PRKACB0.17548383
149CSNK1A10.16904437
150IGF1R0.16260216
151IRAK10.16165797
152KDR0.15843860
153TLK10.15260961
154PRKCZ0.15112833
155DYRK1B0.14664919
156JAK10.14392266
157GRK50.13470180
158TEC0.12767453

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006014.28083180
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.01392080
3Mineral absorption_Homo sapiens_hsa049783.89531272
4Fat digestion and absorption_Homo sapiens_hsa049753.68181070
5Renin-angiotensin system_Homo sapiens_hsa046143.34051359
6Vitamin digestion and absorption_Homo sapiens_hsa049772.75878263
7Olfactory transduction_Homo sapiens_hsa047402.40501140
8Sulfur metabolism_Homo sapiens_hsa009202.22729324
9Sphingolipid metabolism_Homo sapiens_hsa006002.09106229
10Bile secretion_Homo sapiens_hsa049762.08750611
11Sulfur relay system_Homo sapiens_hsa041222.00747806
12Steroid biosynthesis_Homo sapiens_hsa001002.00633341
13Protein digestion and absorption_Homo sapiens_hsa049741.82324396
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.80442633
15Arginine biosynthesis_Homo sapiens_hsa002201.73449997
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.73096404
17Galactose metabolism_Homo sapiens_hsa000521.71824455
18Cyanoamino acid metabolism_Homo sapiens_hsa004601.71580106
19Caffeine metabolism_Homo sapiens_hsa002321.71399945
20Histidine metabolism_Homo sapiens_hsa003401.63621069
21Linoleic acid metabolism_Homo sapiens_hsa005911.62095358
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.58756252
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.58310447
24Carbohydrate digestion and absorption_Homo sapiens_hsa049731.55447366
25Retinol metabolism_Homo sapiens_hsa008301.55192562
26Chemical carcinogenesis_Homo sapiens_hsa052041.55074482
27Ether lipid metabolism_Homo sapiens_hsa005651.42116199
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.40947747
29Ovarian steroidogenesis_Homo sapiens_hsa049131.40499636
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.39102109
31Arachidonic acid metabolism_Homo sapiens_hsa005901.37773290
32Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.37455045
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.35633385
34Starch and sucrose metabolism_Homo sapiens_hsa005001.34991588
35Choline metabolism in cancer_Homo sapiens_hsa052311.32929919
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.32846177
37Circadian rhythm_Homo sapiens_hsa047101.31402843
38Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.28377893
39Glycerolipid metabolism_Homo sapiens_hsa005611.26633509
40Tight junction_Homo sapiens_hsa045301.25354258
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.21581330
42Cocaine addiction_Homo sapiens_hsa050301.21420470
43Glycerophospholipid metabolism_Homo sapiens_hsa005641.17742028
44Cell cycle_Homo sapiens_hsa041101.15299261
45Fructose and mannose metabolism_Homo sapiens_hsa000511.12471590
46Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.08843353
47Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.07250890
48Insulin secretion_Homo sapiens_hsa049111.05655908
49TGF-beta signaling pathway_Homo sapiens_hsa043501.05612454
50Folate biosynthesis_Homo sapiens_hsa007901.03751963
51Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03384936
52Adherens junction_Homo sapiens_hsa045201.02253610
53Vibrio cholerae infection_Homo sapiens_hsa051101.00695101
54Gastric acid secretion_Homo sapiens_hsa049710.98999670
55Glutathione metabolism_Homo sapiens_hsa004800.94361708
56Gap junction_Homo sapiens_hsa045400.93942601
57Pancreatic cancer_Homo sapiens_hsa052120.92343331
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90388405
59Other glycan degradation_Homo sapiens_hsa005110.88841439
60Basal transcription factors_Homo sapiens_hsa030220.88649700
61GnRH signaling pathway_Homo sapiens_hsa049120.87657595
62Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.86317065
63Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.85783216
64Dorso-ventral axis formation_Homo sapiens_hsa043200.84643170
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.82046702
66Thyroid cancer_Homo sapiens_hsa052160.80354713
67Amphetamine addiction_Homo sapiens_hsa050310.79193427
68Collecting duct acid secretion_Homo sapiens_hsa049660.74104009
69Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.73860281
70Hepatitis C_Homo sapiens_hsa051600.73694933
71Arginine and proline metabolism_Homo sapiens_hsa003300.71714073
72Phenylalanine metabolism_Homo sapiens_hsa003600.70451214
73p53 signaling pathway_Homo sapiens_hsa041150.70441218
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.67388195
75Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66839530
76Asthma_Homo sapiens_hsa053100.66657399
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.66382903
78Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.66324184
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.65624278
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65584743
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63649229
82RNA degradation_Homo sapiens_hsa030180.62366469
83Bladder cancer_Homo sapiens_hsa052190.62282910
84Thyroid hormone synthesis_Homo sapiens_hsa049180.59590493
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58886176
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58196863
87Circadian entrainment_Homo sapiens_hsa047130.57916703
88Hippo signaling pathway_Homo sapiens_hsa043900.57412524
89Long-term depression_Homo sapiens_hsa047300.57090133
90Inositol phosphate metabolism_Homo sapiens_hsa005620.56301847
91Pyruvate metabolism_Homo sapiens_hsa006200.56219850
92Glutamatergic synapse_Homo sapiens_hsa047240.54815631
93Taste transduction_Homo sapiens_hsa047420.54207243
94Staphylococcus aureus infection_Homo sapiens_hsa051500.54168597
95Salmonella infection_Homo sapiens_hsa051320.53551491
96Fatty acid degradation_Homo sapiens_hsa000710.52961041
97Cholinergic synapse_Homo sapiens_hsa047250.52777175
98Pancreatic secretion_Homo sapiens_hsa049720.52433765
99Melanogenesis_Homo sapiens_hsa049160.49963596
100Synaptic vesicle cycle_Homo sapiens_hsa047210.48124805
101Steroid hormone biosynthesis_Homo sapiens_hsa001400.46854943
102Allograft rejection_Homo sapiens_hsa053300.46090117
103RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45743058
104Serotonergic synapse_Homo sapiens_hsa047260.45352271
105Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.44788497
106Hematopoietic cell lineage_Homo sapiens_hsa046400.44784880
107Estrogen signaling pathway_Homo sapiens_hsa049150.44736305
108Renin secretion_Homo sapiens_hsa049240.44037618
109Autoimmune thyroid disease_Homo sapiens_hsa053200.43689530
110MicroRNAs in cancer_Homo sapiens_hsa052060.42894605
111Graft-versus-host disease_Homo sapiens_hsa053320.41429275
112Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41417242
113Prolactin signaling pathway_Homo sapiens_hsa049170.41074162
114PPAR signaling pathway_Homo sapiens_hsa033200.41009868
115Salivary secretion_Homo sapiens_hsa049700.40732242
116Platelet activation_Homo sapiens_hsa046110.39889489
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.39731384
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.39001479
119Dilated cardiomyopathy_Homo sapiens_hsa054140.38868272
120Tryptophan metabolism_Homo sapiens_hsa003800.38686889
121TNF signaling pathway_Homo sapiens_hsa046680.37966761
122Influenza A_Homo sapiens_hsa051640.36869576
123Non-homologous end-joining_Homo sapiens_hsa034500.36864347
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36274387
125Type I diabetes mellitus_Homo sapiens_hsa049400.35349722
126Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.33998865
127ErbB signaling pathway_Homo sapiens_hsa040120.32707837
128Colorectal cancer_Homo sapiens_hsa052100.32327349
129beta-Alanine metabolism_Homo sapiens_hsa004100.31517823
130Glucagon signaling pathway_Homo sapiens_hsa049220.31045157
131Chemokine signaling pathway_Homo sapiens_hsa040620.30291878
132Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29946550
133Vascular smooth muscle contraction_Homo sapiens_hsa042700.29782836
134Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29650654
135GABAergic synapse_Homo sapiens_hsa047270.29206570
136Calcium signaling pathway_Homo sapiens_hsa040200.28282698
137NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27241383
138Fanconi anemia pathway_Homo sapiens_hsa034600.27205000
139Leukocyte transendothelial migration_Homo sapiens_hsa046700.27029834
140Insulin resistance_Homo sapiens_hsa049310.26862431
141Purine metabolism_Homo sapiens_hsa002300.25766430
142Oxytocin signaling pathway_Homo sapiens_hsa049210.25142668
143Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24848554
144Endometrial cancer_Homo sapiens_hsa052130.23884528
145VEGF signaling pathway_Homo sapiens_hsa043700.23464142
146Tyrosine metabolism_Homo sapiens_hsa003500.23416140
147Phospholipase D signaling pathway_Homo sapiens_hsa040720.23291870
148Morphine addiction_Homo sapiens_hsa050320.22663238
149ABC transporters_Homo sapiens_hsa020100.22035834
150Ras signaling pathway_Homo sapiens_hsa040140.21203015
151Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.20941265
152Prostate cancer_Homo sapiens_hsa052150.20297902
153Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.19860542
154Type II diabetes mellitus_Homo sapiens_hsa049300.17505509
155Small cell lung cancer_Homo sapiens_hsa052220.17202830

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