

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.55255808 |
| 2 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 6.28759908 |
| 3 | positive thymic T cell selection (GO:0045059) | 5.60540590 |
| 4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.55910756 |
| 5 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 5.50590203 |
| 6 | post-embryonic morphogenesis (GO:0009886) | 5.40294255 |
| 7 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.30207418 |
| 8 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.28719345 |
| 9 | negative thymic T cell selection (GO:0045060) | 5.11702568 |
| 10 | negative T cell selection (GO:0043383) | 5.00305768 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.95992067 |
| 12 | negative regulation of cell killing (GO:0031342) | 4.85067978 |
| 13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.85067978 |
| 14 | positive T cell selection (GO:0043368) | 4.78178835 |
| 15 | B cell receptor signaling pathway (GO:0050853) | 4.77566852 |
| 16 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.67970197 |
| 17 | response to pheromone (GO:0019236) | 4.55454375 |
| 18 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.44146331 |
| 19 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.23701964 |
| 20 | tolerance induction (GO:0002507) | 4.12263449 |
| 21 | thymic T cell selection (GO:0045061) | 4.02476232 |
| 22 | negative regulation of T cell mediated immunity (GO:0002710) | 3.89030884 |
| 23 | regulation of regulatory T cell differentiation (GO:0045589) | 3.77511682 |
| 24 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.69689437 |
| 25 | activated T cell proliferation (GO:0050798) | 3.67772858 |
| 26 | energy homeostasis (GO:0097009) | 3.64206470 |
| 27 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.57072709 |
| 28 | T cell selection (GO:0045058) | 3.56009997 |
| 29 | response to interleukin-15 (GO:0070672) | 3.55459521 |
| 30 | defense response to protozoan (GO:0042832) | 3.53146295 |
| 31 | cellular response to interleukin-15 (GO:0071350) | 3.52991899 |
| 32 | immunoglobulin mediated immune response (GO:0016064) | 3.48077937 |
| 33 | regulation of antigen processing and presentation (GO:0002577) | 3.46024238 |
| 34 | histone H3-K9 modification (GO:0061647) | 3.44006479 |
| 35 | regulation of T cell tolerance induction (GO:0002664) | 3.41957496 |
| 36 | positive regulation of antigen processing and presentation (GO:0002579) | 3.40182206 |
| 37 | cellular extravasation (GO:0045123) | 3.39319428 |
| 38 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.36284431 |
| 39 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.33300431 |
| 40 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.30301388 |
| 41 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.26966301 |
| 42 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.26966301 |
| 43 | modulation by symbiont of host immune response (GO:0052553) | 3.26966301 |
| 44 | positive regulation by symbiont of host defense response (GO:0052509) | 3.26966301 |
| 45 | modulation by symbiont of host defense response (GO:0052031) | 3.26966301 |
| 46 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.26966301 |
| 47 | positive regulation of type 2 immune response (GO:0002830) | 3.26125069 |
| 48 | cell wall macromolecule catabolic process (GO:0016998) | 3.25020454 |
| 49 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.24420928 |
| 50 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.24420928 |
| 51 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.24296050 |
| 52 | base-excision repair, AP site formation (GO:0006285) | 3.24229242 |
| 53 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.23820644 |
| 54 | positive regulation of tolerance induction (GO:0002645) | 3.22813912 |
| 55 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.19285333 |
| 56 | response to protozoan (GO:0001562) | 3.18530764 |
| 57 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.13759401 |
| 58 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.11573081 |
| 59 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.11125978 |
| 60 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.11092789 |
| 61 | regulation of gamma-delta T cell activation (GO:0046643) | 3.08981360 |
| 62 | regulation of tolerance induction (GO:0002643) | 3.08825565 |
| 63 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.08408816 |
| 64 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.08408816 |
| 65 | G-protein coupled receptor internalization (GO:0002031) | 3.06638041 |
| 66 | respiratory burst (GO:0045730) | 3.05845028 |
| 67 | mast cell activation (GO:0045576) | 3.05752148 |
| 68 | mitochondrial DNA replication (GO:0006264) | 3.05112646 |
| 69 | regulation of B cell differentiation (GO:0045577) | 2.99976311 |
| 70 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.97467210 |
| 71 | leukocyte aggregation (GO:0070486) | 2.96127523 |
| 72 | leukocyte degranulation (GO:0043299) | 2.94740664 |
| 73 | regulation of cell killing (GO:0031341) | 2.94331315 |
| 74 | T cell receptor signaling pathway (GO:0050852) | 2.94191654 |
| 75 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.93736299 |
| 76 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.91566893 |
| 77 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.90140131 |
| 78 | lymphocyte homeostasis (GO:0002260) | 2.90010175 |
| 79 | positive regulation of humoral immune response (GO:0002922) | 2.89323058 |
| 80 | polyamine biosynthetic process (GO:0006596) | 2.89028353 |
| 81 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.88049080 |
| 82 | T cell migration (GO:0072678) | 2.87492059 |
| 83 | mannose metabolic process (GO:0006013) | 2.84208130 |
| 84 | positive regulation of cell killing (GO:0031343) | 2.83834366 |
| 85 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.83761345 |
| 86 | oogenesis (GO:0048477) | 2.76583104 |
| 87 | type I interferon signaling pathway (GO:0060337) | 2.76482076 |
| 88 | cellular response to type I interferon (GO:0071357) | 2.76482076 |
| 89 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.75315076 |
| 90 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.74959964 |
| 91 | response to type I interferon (GO:0034340) | 2.74698738 |
| 92 | negative regulation of B cell apoptotic process (GO:0002903) | 2.71537974 |
| 93 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.71354937 |
| 94 | B cell homeostasis (GO:0001782) | 2.70235719 |
| 95 | outer ear morphogenesis (GO:0042473) | 2.69586608 |
| 96 | negative regulation of interleukin-6 production (GO:0032715) | 2.69020962 |
| 97 | negative regulation of innate immune response (GO:0045824) | 2.68995683 |
| 98 | positive regulation of macrophage cytokine production (GO:0060907) | 2.68827946 |
| 99 | histone H3-K9 methylation (GO:0051567) | 2.68030784 |
| 100 | cell wall macromolecule metabolic process (GO:0044036) | 2.67265837 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.61594127 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.23263651 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.60694073 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.51752721 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.29368609 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.22024063 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.19769739 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.09492174 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 3.09484929 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.00149434 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.91312820 |
| 12 | MYB_26560356_Chip-Seq_TH2_Human | 2.82640887 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.57012679 |
| 14 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.49368800 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.40881729 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.38824439 |
| 17 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.36989043 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.30881417 |
| 19 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.26103766 |
| 20 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.25091957 |
| 21 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.11313382 |
| 22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.10267005 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99743386 |
| 24 | MAF_26560356_Chip-Seq_TH1_Human | 1.99147661 |
| 25 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.87529886 |
| 26 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.86274850 |
| 27 | GATA3_26560356_Chip-Seq_TH2_Human | 1.83936204 |
| 28 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.79734913 |
| 29 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.77344342 |
| 30 | UTX_26944678_Chip-Seq_JUKART_Human | 1.75717402 |
| 31 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.73211052 |
| 32 | SPI1_23127762_ChIP-Seq_K562_Human | 1.72505175 |
| 33 | MYC_22102868_ChIP-Seq_BL_Human | 1.71003516 |
| 34 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.69730658 |
| 35 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57355166 |
| 36 | MAF_26560356_Chip-Seq_TH2_Human | 1.56820374 |
| 37 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.46779222 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.38654932 |
| 39 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.37656879 |
| 40 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36217733 |
| 41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.33405218 |
| 42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.32959134 |
| 43 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.31454177 |
| 44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.28721029 |
| 45 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.23848668 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22942112 |
| 47 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.22721172 |
| 48 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.21264315 |
| 49 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19928331 |
| 50 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.19056506 |
| 51 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.18977023 |
| 52 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.17565842 |
| 53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.17313518 |
| 54 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.17186877 |
| 55 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.16444412 |
| 56 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14970318 |
| 57 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.11255881 |
| 58 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.10574678 |
| 59 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.07274552 |
| 60 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06074566 |
| 61 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.05588642 |
| 62 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.05124836 |
| 63 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.04728304 |
| 64 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04264942 |
| 65 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03451358 |
| 66 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.02377215 |
| 67 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.00362527 |
| 68 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00030991 |
| 69 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.00029782 |
| 70 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99517495 |
| 71 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.98830319 |
| 72 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.98246823 |
| 73 | GATA1_22025678_ChIP-Seq_K562_Human | 0.98078047 |
| 74 | P300_27268052_Chip-Seq_Bcells_Human | 0.97632226 |
| 75 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.95729113 |
| 76 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.94595047 |
| 77 | GATA3_26560356_Chip-Seq_TH1_Human | 0.94444232 |
| 78 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.93022513 |
| 79 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.91154024 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89302899 |
| 81 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.89141560 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.88317665 |
| 83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.87873599 |
| 84 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.87873599 |
| 85 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.87120652 |
| 86 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.86720269 |
| 87 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85207067 |
| 88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.84493485 |
| 89 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.84355402 |
| 90 | GATA1_19941826_ChIP-Seq_K562_Human | 0.83302831 |
| 91 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.82614218 |
| 92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.81907764 |
| 93 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81262531 |
| 94 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.81184864 |
| 95 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.80889689 |
| 96 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.80733865 |
| 97 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.79978156 |
| 98 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.79809592 |
| 99 | RXR_22108803_ChIP-Seq_LS180_Human | 0.79560369 |
| 100 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79206810 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005451_abnormal_body_composition | 4.16935243 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.84502076 |
| 3 | MP0005671_abnormal_response_to | 3.79887131 |
| 4 | MP0001790_abnormal_immune_system | 3.56613897 |
| 5 | MP0005387_immune_system_phenotype | 3.56613897 |
| 6 | MP0003724_increased_susceptibility_to | 3.48468313 |
| 7 | MP0000685_abnormal_immune_system | 3.40538164 |
| 8 | MP0001800_abnormal_humoral_immune | 3.19622362 |
| 9 | MP0003436_decreased_susceptibility_to | 3.01462677 |
| 10 | MP0003763_abnormal_thymus_physiology | 2.93911540 |
| 11 | MP0002138_abnormal_hepatobiliary_system | 2.85228910 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.66701278 |
| 13 | MP0002723_abnormal_immune_serum | 2.60468376 |
| 14 | MP0001873_stomach_inflammation | 2.57141683 |
| 15 | MP0002452_abnormal_antigen_presenting | 2.47927754 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.47333745 |
| 17 | MP0001819_abnormal_immune_cell | 2.44367587 |
| 18 | MP0002419_abnormal_innate_immunity | 2.27268751 |
| 19 | MP0005025_abnormal_response_to | 2.25772547 |
| 20 | MP0003303_peritoneal_inflammation | 2.24028887 |
| 21 | MP0000465_gastrointestinal_hemorrhage | 2.23009783 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 2.08292895 |
| 23 | MP0002398_abnormal_bone_marrow | 2.02657842 |
| 24 | MP0003646_muscle_fatigue | 2.00136040 |
| 25 | MP0000716_abnormal_immune_system | 1.96062297 |
| 26 | MP0003172_abnormal_lysosome_physiology | 1.96045334 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 1.95494366 |
| 28 | MP0000689_abnormal_spleen_morphology | 1.90038189 |
| 29 | MP0009785_altered_susceptibility_to | 1.86886334 |
| 30 | MP0002722_abnormal_immune_system | 1.75608179 |
| 31 | MP0000703_abnormal_thymus_morphology | 1.75398174 |
| 32 | MP0002332_abnormal_exercise_endurance | 1.68037718 |
| 33 | MP0003866_abnormal_defecation | 1.67687698 |
| 34 | MP0003011_delayed_dark_adaptation | 1.66598350 |
| 35 | MP0005075_abnormal_melanosome_morpholog | 1.65629464 |
| 36 | MP0002429_abnormal_blood_cell | 1.53318039 |
| 37 | MP0004947_skin_inflammation | 1.52509346 |
| 38 | MP0002405_respiratory_system_inflammati | 1.51144038 |
| 39 | MP0010155_abnormal_intestine_physiology | 1.50548405 |
| 40 | MP0002396_abnormal_hematopoietic_system | 1.49149000 |
| 41 | MP0008872_abnormal_physiological_respon | 1.47786843 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.46887010 |
| 43 | MP0001986_abnormal_taste_sensitivity | 1.39216040 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.36254505 |
| 45 | MP0004381_abnormal_hair_follicle | 1.29175798 |
| 46 | MP0001533_abnormal_skeleton_physiology | 1.26162482 |
| 47 | MP0005464_abnormal_platelet_physiology | 1.24786369 |
| 48 | MP0002009_preneoplasia | 1.22134461 |
| 49 | MP0003638_abnormal_response/metabolism_ | 1.21344708 |
| 50 | MP0005253_abnormal_eye_physiology | 1.19291640 |
| 51 | MP0004147_increased_porphyrin_level | 1.17152035 |
| 52 | MP0003806_abnormal_nucleotide_metabolis | 1.14348455 |
| 53 | MP0003252_abnormal_bile_duct | 1.13919390 |
| 54 | MP0009764_decreased_sensitivity_to | 1.12980995 |
| 55 | MP0002877_abnormal_melanocyte_morpholog | 1.09642031 |
| 56 | MP0006082_CNS_inflammation | 1.07129827 |
| 57 | MP0008469_abnormal_protein_level | 1.06702328 |
| 58 | MP0002933_joint_inflammation | 1.06142544 |
| 59 | MP0002876_abnormal_thyroid_physiology | 1.03655973 |
| 60 | MP0003300_gastrointestinal_ulcer | 1.03573026 |
| 61 | MP0009278_abnormal_bone_marrow | 1.01727410 |
| 62 | MP0003828_pulmonary_edema | 0.99152813 |
| 63 | MP0003183_abnormal_peptide_metabolism | 0.95471865 |
| 64 | MP0001851_eye_inflammation | 0.91484195 |
| 65 | MP0004130_abnormal_muscle_cell | 0.91103783 |
| 66 | MP0005310_abnormal_salivary_gland | 0.89304002 |
| 67 | MP0000858_altered_metastatic_potential | 0.83335055 |
| 68 | MP0002095_abnormal_skin_pigmentation | 0.82279525 |
| 69 | MP0002693_abnormal_pancreas_physiology | 0.81242936 |
| 70 | MP0004043_abnormal_pH_regulation | 0.80902831 |
| 71 | MP0001663_abnormal_digestive_system | 0.79082999 |
| 72 | MP0008995_early_reproductive_senescence | 0.78114821 |
| 73 | MP0000569_abnormal_digit_pigmentation | 0.77540959 |
| 74 | MP0003656_abnormal_erythrocyte_physiolo | 0.75905905 |
| 75 | MP0002928_abnormal_bile_duct | 0.74881037 |
| 76 | MP0002254_reproductive_system_inflammat | 0.74676235 |
| 77 | MP0004510_myositis | 0.71283730 |
| 78 | MP0000490_abnormal_crypts_of | 0.70674705 |
| 79 | MP0000678_abnormal_parathyroid_gland | 0.69398735 |
| 80 | MP0002277_abnormal_respiratory_mucosa | 0.69173787 |
| 81 | MP0002132_abnormal_respiratory_system | 0.68718234 |
| 82 | MP0002166_altered_tumor_susceptibility | 0.68430611 |
| 83 | MP0004808_abnormal_hematopoietic_stem | 0.64992353 |
| 84 | MP0002019_abnormal_tumor_incidence | 0.63136515 |
| 85 | MP0005551_abnormal_eye_electrophysiolog | 0.62751103 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.62153576 |
| 87 | MP0002735_abnormal_chemical_nociception | 0.60112713 |
| 88 | MP0002998_abnormal_bone_remodeling | 0.59991858 |
| 89 | MP0003195_calcinosis | 0.59549616 |
| 90 | MP0005535_abnormal_body_temperature | 0.58055787 |
| 91 | MP0009763_increased_sensitivity_to | 0.57866815 |
| 92 | MP0005085_abnormal_gallbladder_physiolo | 0.57715190 |
| 93 | MP0002733_abnormal_thermal_nociception | 0.57498369 |
| 94 | MP0004036_abnormal_muscle_relaxation | 0.56299892 |
| 95 | MP0000681_abnormal_thyroid_gland | 0.56083256 |
| 96 | MP0000249_abnormal_blood_vessel | 0.53737749 |
| 97 | MP0008875_abnormal_xenobiotic_pharmacok | 0.51667569 |
| 98 | MP0005397_hematopoietic_system_phenotyp | 0.50349028 |
| 99 | MP0001545_abnormal_hematopoietic_system | 0.50349028 |
| 100 | MP0002136_abnormal_kidney_physiology | 0.48386947 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 7.38443690 |
| 2 | Congenital stationary night blindness (HP:0007642) | 7.17033113 |
| 3 | Chronic sinusitis (HP:0011109) | 4.71666604 |
| 4 | Recurrent bronchitis (HP:0002837) | 4.66462783 |
| 5 | Cellulitis (HP:0100658) | 4.32418052 |
| 6 | 11 pairs of ribs (HP:0000878) | 4.30353339 |
| 7 | Progressive external ophthalmoplegia (HP:0000590) | 4.26620966 |
| 8 | Persistence of primary teeth (HP:0006335) | 4.16181924 |
| 9 | Meningitis (HP:0001287) | 4.07536023 |
| 10 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.02398944 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.97958484 |
| 12 | Verrucae (HP:0200043) | 3.89136007 |
| 13 | Papilloma (HP:0012740) | 3.89136007 |
| 14 | Flared iliac wings (HP:0002869) | 3.82171923 |
| 15 | Short nail (HP:0001799) | 3.58056104 |
| 16 | Prostate neoplasm (HP:0100787) | 3.47029080 |
| 17 | Recurrent bacterial skin infections (HP:0005406) | 3.30443182 |
| 18 | Abnormality of the prostate (HP:0008775) | 3.24658620 |
| 19 | Panhypogammaglobulinemia (HP:0003139) | 3.23807745 |
| 20 | Abnormality of binocular vision (HP:0011514) | 3.22826218 |
| 21 | Diplopia (HP:0000651) | 3.22826218 |
| 22 | Stomatitis (HP:0010280) | 3.19026364 |
| 23 | Recurrent pneumonia (HP:0006532) | 3.17210967 |
| 24 | Myositis (HP:0100614) | 3.13597056 |
| 25 | Eczematoid dermatitis (HP:0000976) | 3.03659945 |
| 26 | Recurrent abscess formation (HP:0002722) | 2.98990529 |
| 27 | IgG deficiency (HP:0004315) | 2.92368787 |
| 28 | Gastrointestinal infarctions (HP:0005244) | 2.92085796 |
| 29 | Recurrent fungal infections (HP:0002841) | 2.87424524 |
| 30 | Protruding tongue (HP:0010808) | 2.85666928 |
| 31 | Broad distal phalanx of finger (HP:0009836) | 2.83679200 |
| 32 | Clumsiness (HP:0002312) | 2.81357454 |
| 33 | Osteomyelitis (HP:0002754) | 2.80633164 |
| 34 | Encephalitis (HP:0002383) | 2.78245100 |
| 35 | T lymphocytopenia (HP:0005403) | 2.71250168 |
| 36 | Optic neuritis (HP:0100653) | 2.71133347 |
| 37 | Retrobulbar optic neuritis (HP:0100654) | 2.71133347 |
| 38 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.70031939 |
| 39 | Abnormality of T cell number (HP:0011839) | 2.65562216 |
| 40 | Sepsis (HP:0100806) | 2.64335702 |
| 41 | Bronchitis (HP:0012387) | 2.63089615 |
| 42 | Spontaneous hematomas (HP:0007420) | 2.60796725 |
| 43 | Abnormality of T cells (HP:0002843) | 2.59913838 |
| 44 | Recurrent lower respiratory tract infections (HP:0002783) | 2.57454630 |
| 45 | Skin rash (HP:0000988) | 2.55580915 |
| 46 | Vasculitis (HP:0002633) | 2.55464996 |
| 47 | Recurrent viral infections (HP:0004429) | 2.54147783 |
| 48 | Orchitis (HP:0100796) | 2.50589891 |
| 49 | Chronic obstructive pulmonary disease (HP:0006510) | 2.50006056 |
| 50 | Obstructive lung disease (HP:0006536) | 2.50006056 |
| 51 | Bicuspid aortic valve (HP:0001647) | 2.49779364 |
| 52 | Radial bowing (HP:0002986) | 2.45544888 |
| 53 | Abnormality of macrophages (HP:0004311) | 2.39446912 |
| 54 | Recurrent cutaneous fungal infections (HP:0011370) | 2.36987718 |
| 55 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.36987718 |
| 56 | Stomach cancer (HP:0012126) | 2.35927763 |
| 57 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.27711760 |
| 58 | Inflammation of the large intestine (HP:0002037) | 2.26310596 |
| 59 | Lymphopenia (HP:0001888) | 2.25451083 |
| 60 | Gastrointestinal stroma tumor (HP:0100723) | 2.25216658 |
| 61 | Abnormality of T cell physiology (HP:0011840) | 2.25029069 |
| 62 | Recurrent otitis media (HP:0000403) | 2.23739013 |
| 63 | IgM deficiency (HP:0002850) | 2.23159638 |
| 64 | Recurrent skin infections (HP:0001581) | 2.22500377 |
| 65 | Gingivitis (HP:0000230) | 2.19451291 |
| 66 | Pustule (HP:0200039) | 2.17794421 |
| 67 | Prolonged bleeding time (HP:0003010) | 2.17260425 |
| 68 | Genetic anticipation (HP:0003743) | 2.08374328 |
| 69 | Abnormality of male internal genitalia (HP:0000022) | 2.06638928 |
| 70 | Coxa valga (HP:0002673) | 2.05738241 |
| 71 | Gastrointestinal inflammation (HP:0004386) | 2.04494826 |
| 72 | Mediastinal lymphadenopathy (HP:0100721) | 2.02614133 |
| 73 | Glucose intolerance (HP:0000833) | 2.01579583 |
| 74 | Abnormality of B cell number (HP:0010975) | 2.01414394 |
| 75 | Hemoptysis (HP:0002105) | 1.99248570 |
| 76 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.93072889 |
| 77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.89985865 |
| 78 | Leukocytosis (HP:0001974) | 1.89562462 |
| 79 | Hematochezia (HP:0002573) | 1.89438121 |
| 80 | Proximal tubulopathy (HP:0000114) | 1.88003276 |
| 81 | Joint swelling (HP:0001386) | 1.86350410 |
| 82 | Hypochromic anemia (HP:0001931) | 1.85703812 |
| 83 | Abnormal glucose tolerance (HP:0001952) | 1.85655973 |
| 84 | Pulmonary infiltrates (HP:0002113) | 1.85496015 |
| 85 | Hypochromic microcytic anemia (HP:0004840) | 1.84864665 |
| 86 | Colitis (HP:0002583) | 1.84125814 |
| 87 | External ophthalmoplegia (HP:0000544) | 1.83692218 |
| 88 | Delayed CNS myelination (HP:0002188) | 1.83488803 |
| 89 | Chronic otitis media (HP:0000389) | 1.82535692 |
| 90 | Supernumerary spleens (HP:0009799) | 1.81586984 |
| 91 | Keratoconjunctivitis sicca (HP:0001097) | 1.80750088 |
| 92 | Increased IgE level (HP:0003212) | 1.80618410 |
| 93 | Annular pancreas (HP:0001734) | 1.78334891 |
| 94 | Large for gestational age (HP:0001520) | 1.77623794 |
| 95 | Keratoconjunctivitis (HP:0001096) | 1.75471830 |
| 96 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.75351241 |
| 97 | Urticaria (HP:0001025) | 1.75113499 |
| 98 | Thrombocytosis (HP:0001894) | 1.73910171 |
| 99 | Abnormal vertebral ossification (HP:0100569) | 1.73379322 |
| 100 | Cupped ribs (HP:0000887) | 1.72907024 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK1 | 5.02986202 |
| 2 | ACVR1B | 2.88696367 |
| 3 | MAP4K1 | 2.72658573 |
| 4 | TIE1 | 2.39367608 |
| 5 | SIK3 | 2.36796513 |
| 6 | MAP3K13 | 2.01509642 |
| 7 | TESK2 | 11.1275197 |
| 8 | SIK2 | 1.95038055 |
| 9 | TLK1 | 1.92001957 |
| 10 | TXK | 1.91889869 |
| 11 | RIPK4 | 1.81290212 |
| 12 | IRAK4 | 1.79298975 |
| 13 | ITK | 1.72319114 |
| 14 | TYK2 | 1.70114961 |
| 15 | MAPKAPK3 | 1.69220644 |
| 16 | TNK2 | 1.53380553 |
| 17 | SYK | 1.52921534 |
| 18 | TEC | 1.49917572 |
| 19 | GRK6 | 1.35221596 |
| 20 | KIT | 1.33125278 |
| 21 | ZAK | 1.30326733 |
| 22 | MARK3 | 1.22774669 |
| 23 | SIK1 | 1.20031424 |
| 24 | FLT3 | 1.17455914 |
| 25 | MAP3K14 | 1.16574091 |
| 26 | BTK | 1.09047581 |
| 27 | MARK2 | 1.05424068 |
| 28 | ZAP70 | 1.03188495 |
| 29 | FES | 0.99852750 |
| 30 | JAK3 | 0.98571067 |
| 31 | CSF1R | 0.98177519 |
| 32 | KSR2 | 0.97697929 |
| 33 | LCK | 0.94587821 |
| 34 | IKBKE | 0.92375707 |
| 35 | HCK | 0.91649318 |
| 36 | BMPR1B | 0.90677948 |
| 37 | ICK | 0.90342827 |
| 38 | MAP3K11 | 0.85428145 |
| 39 | TBK1 | 0.83085601 |
| 40 | CSK | 0.81308204 |
| 41 | LYN | 0.81106714 |
| 42 | ADRBK2 | 0.78561461 |
| 43 | BLK | 0.71740371 |
| 44 | TAOK3 | 0.71026453 |
| 45 | CCNB1 | 0.67352884 |
| 46 | CAMKK1 | 0.66544011 |
| 47 | PRKCQ | 0.63714029 |
| 48 | STK16 | 0.61914094 |
| 49 | MAP2K3 | 0.57045322 |
| 50 | BMPR2 | 0.54789859 |
| 51 | MAP3K1 | 0.53779191 |
| 52 | CAMKK2 | 0.53332276 |
| 53 | IKBKB | 0.53210616 |
| 54 | TRPM7 | 0.52182883 |
| 55 | WNK1 | 0.52017578 |
| 56 | EIF2AK3 | 0.50983371 |
| 57 | IRAK1 | 0.50411230 |
| 58 | RAF1 | 0.50133321 |
| 59 | JAK1 | 0.50099822 |
| 60 | PRPF4B | 0.48423027 |
| 61 | MST4 | 0.45554125 |
| 62 | MAP2K2 | 0.44718049 |
| 63 | TGFBR1 | 0.42111117 |
| 64 | TAOK1 | 0.40693909 |
| 65 | FRK | 0.40455935 |
| 66 | PRKD2 | 0.38502030 |
| 67 | MAP3K2 | 0.38229607 |
| 68 | JAK2 | 0.37916192 |
| 69 | NLK | 0.34885095 |
| 70 | KDR | 0.33080224 |
| 71 | NTRK3 | 0.32316425 |
| 72 | PIK3CG | 0.31426871 |
| 73 | MAPK7 | 0.31063778 |
| 74 | HIPK2 | 0.29234052 |
| 75 | MAPK12 | 0.27920565 |
| 76 | MAP2K1 | 0.27918064 |
| 77 | CDK19 | 0.27291628 |
| 78 | MAPK11 | 0.27159003 |
| 79 | PIM1 | 0.26145081 |
| 80 | RET | 0.25878474 |
| 81 | LRRK2 | 0.25684842 |
| 82 | INSRR | 0.25036536 |
| 83 | FYN | 0.24964309 |
| 84 | PRKCH | 0.23713279 |
| 85 | PDK1 | 0.21944144 |
| 86 | KSR1 | 0.21898013 |
| 87 | MAP3K9 | 0.19873516 |
| 88 | PTK2B | 0.19819053 |
| 89 | CAMK1D | 0.18744280 |
| 90 | ARAF | 0.18264554 |
| 91 | MAP3K10 | 0.17687685 |
| 92 | CHUK | 0.17396341 |
| 93 | ERN1 | 0.16790786 |
| 94 | CDK4 | 0.16732728 |
| 95 | PRKD1 | 0.15942529 |
| 96 | INSR | 0.14845569 |
| 97 | TGFBR2 | 0.14540215 |
| 98 | STK10 | 0.14434709 |
| 99 | IGF1R | 0.13985397 |
| 100 | MAPKAPK2 | 0.13873543 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.83097225 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.28029357 |
| 3 | Phototransduction_Homo sapiens_hsa04744 | 3.25563998 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.83917737 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.79356234 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.78489331 |
| 7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.63008322 |
| 8 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.35274810 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.30131990 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.13273877 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.09805320 |
| 12 | Leishmaniasis_Homo sapiens_hsa05140 | 2.09601320 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.04672496 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.04662060 |
| 15 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.82170466 |
| 16 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.80155696 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.78436049 |
| 18 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.68712424 |
| 19 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.64696132 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.63502081 |
| 21 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.59046468 |
| 22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.52060172 |
| 23 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.49895297 |
| 24 | Tuberculosis_Homo sapiens_hsa05152 | 1.40945193 |
| 25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.34639846 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.33946231 |
| 27 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.33453932 |
| 28 | Other glycan degradation_Homo sapiens_hsa00511 | 1.33083165 |
| 29 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.28501099 |
| 30 | Viral myocarditis_Homo sapiens_hsa05416 | 1.21366027 |
| 31 | Measles_Homo sapiens_hsa05162 | 1.20754459 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.10455162 |
| 33 | Influenza A_Homo sapiens_hsa05164 | 1.09368025 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.08605689 |
| 35 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.07977320 |
| 36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.01809865 |
| 37 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.00755994 |
| 38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.00679109 |
| 39 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.00289549 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.99580340 |
| 41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.95706054 |
| 42 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.93054349 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.92093055 |
| 44 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.90390277 |
| 45 | ABC transporters_Homo sapiens_hsa02010 | 0.88494601 |
| 46 | Malaria_Homo sapiens_hsa05144 | 0.88214169 |
| 47 | Platelet activation_Homo sapiens_hsa04611 | 0.84411268 |
| 48 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.83775529 |
| 49 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.83361372 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82830177 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.80608731 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78881373 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.77603043 |
| 54 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.73900238 |
| 55 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.73700307 |
| 56 | Hepatitis C_Homo sapiens_hsa05160 | 0.70380761 |
| 57 | Legionellosis_Homo sapiens_hsa05134 | 0.69081088 |
| 58 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.67858014 |
| 59 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.66577071 |
| 60 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.66036855 |
| 61 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.64663713 |
| 62 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63009401 |
| 63 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.60584159 |
| 64 | Morphine addiction_Homo sapiens_hsa05032 | 0.59504397 |
| 65 | HTLV-I infection_Homo sapiens_hsa05166 | 0.59234622 |
| 66 | Hepatitis B_Homo sapiens_hsa05161 | 0.55523083 |
| 67 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.55219725 |
| 68 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.52756863 |
| 69 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48170962 |
| 70 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.46155800 |
| 71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46123528 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45895267 |
| 73 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.45574469 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.44818885 |
| 75 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.44301087 |
| 76 | Phagosome_Homo sapiens_hsa04145 | 0.43935199 |
| 77 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43453425 |
| 78 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.43185628 |
| 79 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.42828823 |
| 80 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.41510950 |
| 81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.40597874 |
| 82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.40404708 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.39889683 |
| 84 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.39351996 |
| 85 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.39030229 |
| 86 | Endocytosis_Homo sapiens_hsa04144 | 0.38656192 |
| 87 | Lysosome_Homo sapiens_hsa04142 | 0.37155131 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.37146290 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.37058885 |
| 90 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.36376921 |
| 91 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36256058 |
| 92 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.35543524 |
| 93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.34747807 |
| 94 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.33735732 |
| 95 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.33484191 |
| 96 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.32051620 |
| 97 | Apoptosis_Homo sapiens_hsa04210 | 0.31606580 |
| 98 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.30203795 |
| 99 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.28760592 |
| 100 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28096433 |

