CEBPB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)5.30765744
2modulation by symbiont of host defense response (GO:0052031)5.30765744
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.30765744
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.30765744
5positive regulation by organism of defense response of other organism involved in symbiotic interact5.30765744
6modulation by symbiont of host immune response (GO:0052553)5.30765744
7response to peptidoglycan (GO:0032494)4.54400288
8apoptotic cell clearance (GO:0043277)4.05385725
9neutrophil activation involved in immune response (GO:0002283)3.92772000
10peptidyl-glutamic acid carboxylation (GO:0017187)3.92113438
11protein carboxylation (GO:0018214)3.92113438
12macrophage activation involved in immune response (GO:0002281)3.83779393
13regulation of interferon-beta biosynthetic process (GO:0045357)3.78139939
14respiratory burst (GO:0045730)3.75820958
15production of molecular mediator involved in inflammatory response (GO:0002532)3.75757688
16negative regulation of cell killing (GO:0031342)3.66752394
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.66752394
18hydrogen peroxide biosynthetic process (GO:0050665)3.65155073
19positive regulation of interferon-alpha production (GO:0032727)3.61458813
20positive regulation of gamma-delta T cell activation (GO:0046645)3.59656177
21germinal center formation (GO:0002467)3.59639774
22low-density lipoprotein particle clearance (GO:0034383)3.59260984
23positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.56328458
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.55305909
25response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.50613473
26response to host immune response (GO:0052572)3.50613473
27regulation of vitamin D biosynthetic process (GO:0060556)3.49051340
28cellular extravasation (GO:0045123)3.46159659
29negative regulation of erythrocyte differentiation (GO:0045647)3.45650230
30response to muramyl dipeptide (GO:0032495)3.43571095
31regulation of interferon-alpha production (GO:0032647)3.43378296
32regulation of cholesterol storage (GO:0010885)3.42232857
33lipopolysaccharide-mediated signaling pathway (GO:0031663)3.39740713
34positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.38387871
35immunoglobulin mediated immune response (GO:0016064)3.37019329
36antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.36034149
37antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.36034149
38cellular response to thyroid hormone stimulus (GO:0097067)3.34780638
39NIK/NF-kappaB signaling (GO:0038061)3.24513997
40reactive oxygen species biosynthetic process (GO:1903409)3.24330856
41detection of bacterium (GO:0016045)3.24189586
42regulation of T-helper 2 cell differentiation (GO:0045628)3.23537293
43detection of molecule of bacterial origin (GO:0032490)3.19364389
44response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.18966347
45response to host (GO:0075136)3.18966347
46response to host defenses (GO:0052200)3.18966347
47positive regulation of toll-like receptor signaling pathway (GO:0034123)3.08527351
48negative regulation of interleukin-12 production (GO:0032695)3.07724318
49negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.04499774
50regulation of membrane protein ectodomain proteolysis (GO:0051043)2.99802809
51detection of biotic stimulus (GO:0009595)2.99584551
52regulation of podosome assembly (GO:0071801)2.95989864
53positive regulation of lipid storage (GO:0010884)2.93240330
54antigen processing and presentation of endogenous antigen (GO:0019883)2.93170200
55response to protozoan (GO:0001562)2.92732537
56plasma lipoprotein particle clearance (GO:0034381)2.92357341
57granulocyte activation (GO:0036230)2.91467855
58defense response to protozoan (GO:0042832)2.91014563
59myeloid dendritic cell differentiation (GO:0043011)2.90944965
60microglial cell activation (GO:0001774)2.90791763
61positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.90712812
62regulation of leukocyte degranulation (GO:0043300)2.89916949
63superoxide anion generation (GO:0042554)2.89870651
64negative regulation of lipid storage (GO:0010888)2.86403892
65positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.84693749
66urea cycle (GO:0000050)2.84497604
67urea metabolic process (GO:0019627)2.84497604
68macrophage activation (GO:0042116)2.84214406
69positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.83601980
70type I interferon signaling pathway (GO:0060337)2.83573926
71cellular response to type I interferon (GO:0071357)2.83573926
72regulation of heterotypic cell-cell adhesion (GO:0034114)2.83329069
73positive regulation of mast cell activation involved in immune response (GO:0033008)2.82863413
74positive regulation of mast cell degranulation (GO:0043306)2.82863413
75positive regulation of p38MAPK cascade (GO:1900745)2.81871612
76regulation of chemokine biosynthetic process (GO:0045073)2.81520648
77glycosphingolipid catabolic process (GO:0046479)2.80417291
78regulation of vitamin metabolic process (GO:0030656)2.80090803
79complement activation, alternative pathway (GO:0006957)2.79532557
80positive regulation of mast cell activation (GO:0033005)2.79019679
81regulation of mast cell degranulation (GO:0043304)2.78707620
82positive regulation of chemokine biosynthetic process (GO:0045080)2.78188676
83regulation of myeloid leukocyte mediated immunity (GO:0002886)2.75830933
84protein localization to endosome (GO:0036010)2.75325055
85neutrophil activation (GO:0042119)2.74689610
86regulation of interleukin-8 biosynthetic process (GO:0045414)2.73197770
87positive regulation of blood coagulation (GO:0030194)2.72768072
88positive regulation of hemostasis (GO:1900048)2.72768072
89positive regulation of antigen processing and presentation (GO:0002579)2.72719541
90positive regulation of cellular amide metabolic process (GO:0034250)2.72564885
91leukocyte aggregation (GO:0070486)2.72277224
92oligosaccharide catabolic process (GO:0009313)2.72109370
93positive regulation of coagulation (GO:0050820)2.71953376
94interferon-gamma-mediated signaling pathway (GO:0060333)2.69071812
95regulation of gamma-delta T cell activation (GO:0046643)2.67218841
96negative regulation of myeloid cell apoptotic process (GO:0033033)2.65464415
97T-helper 1 type immune response (GO:0042088)2.64573303
98phospholipid efflux (GO:0033700)2.63443000
99detection of external biotic stimulus (GO:0098581)2.63349698
100response to thyroid hormone (GO:0097066)2.62687033
101positive regulation of cholesterol efflux (GO:0010875)2.62265380
102positive regulation of interferon-beta production (GO:0032728)2.61961864
103positive regulation of sterol transport (GO:0032373)2.61918439
104positive regulation of cholesterol transport (GO:0032376)2.61918439
105amino sugar catabolic process (GO:0046348)2.61172401
106regulation of mast cell activation involved in immune response (GO:0033006)2.60861970
107triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.59985793
108positive regulation of NF-kappaB import into nucleus (GO:0042346)2.59841475
109positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.59263659
110cellular response to lipopolysaccharide (GO:0071222)2.58801172
111JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.58669775
112positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.58498755
113regulation of B cell receptor signaling pathway (GO:0050855)2.58407056
114myeloid dendritic cell activation (GO:0001773)2.57103583
115nitrogen cycle metabolic process (GO:0071941)2.57082189
116response to laminar fluid shear stress (GO:0034616)2.56564507
117cellular response to molecule of bacterial origin (GO:0071219)2.56229079
118response to fungus (GO:0009620)2.55114868
119I-kappaB phosphorylation (GO:0007252)2.54741765
120positive regulation of type 2 immune response (GO:0002830)2.54166428
121regulation of mononuclear cell migration (GO:0071675)2.54146985
122myeloid cell activation involved in immune response (GO:0002275)2.52743450
123negative regulation of production of molecular mediator of immune response (GO:0002701)2.52629240
124negative regulation of interleukin-6 production (GO:0032715)2.52174198
125positive regulation of interleukin-6 production (GO:0032755)2.51400957
126Arp2/3 complex-mediated actin nucleation (GO:0034314)2.51311591
127detection of other organism (GO:0098543)2.51257348
128disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.51066732
129killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.51066732
130negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.50453704
131neutrophil chemotaxis (GO:0030593)2.49967966
132regulation of T cell tolerance induction (GO:0002664)2.48708870
133regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)2.47783816
134monocyte chemotaxis (GO:0002548)2.47718924
135regulation of T-helper 1 cell differentiation (GO:0045625)2.47524934
136regulation of mast cell activation (GO:0033003)2.44522115
137positive regulation of lipid catabolic process (GO:0050996)2.44290933
138lipoxygenase pathway (GO:0019372)2.43017535
139positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.42990598
140negative regulation of cytokine production involved in immune response (GO:0002719)2.42879508
141regulation of dendritic cell antigen processing and presentation (GO:0002604)2.42606300
142response to type I interferon (GO:0034340)2.41703838
143positive regulation of leukocyte degranulation (GO:0043302)2.41594636
144regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.41445130
145B cell mediated immunity (GO:0019724)2.41109774

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.32787978
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.26297334
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.24290598
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.03676035
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.39522706
6* RXR_22158963_ChIP-Seq_LIVER_Mouse3.23071120
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.20821250
8Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.05979294
9NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.03541781
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.96878314
11PPARA_22158963_ChIP-Seq_LIVER_Mouse2.96050739
12* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.88267690
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.79164548
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.78979463
15RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.72546213
16LXR_22158963_ChIP-Seq_LIVER_Mouse2.68970933
17* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.67345377
18IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.64923566
19NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.63891544
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.45591798
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.42778379
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.28186723
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.26704317
24BRD4_27068464_Chip-Seq_AML-cells_Mouse2.23050943
25EGR1_23403033_ChIP-Seq_LIVER_Mouse2.20682400
26FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.18151843
27STAT6_21828071_ChIP-Seq_BEAS2B_Human2.04580117
28IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.04541230
29THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.98016745
30FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.96761362
31STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.85792445
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.85728916
33* RARG_19884340_ChIP-ChIP_MEFs_Mouse1.83758112
34* VDR_24763502_ChIP-Seq_THP-1_Human1.76220621
35CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.73433887
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.68757662
37CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.67118633
38PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.64544414
39VDR_21846776_ChIP-Seq_THP-1_Human1.64162613
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.60880950
41* CLOCK_20551151_ChIP-Seq_293T_Human1.60329271
42TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.59318800
43ELK3_25401928_ChIP-Seq_HUVEC_Human1.50792623
44* MAF_26560356_Chip-Seq_TH1_Human1.49387219
45* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.47921241
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46961341
47TRIM28_21343339_ChIP-Seq_HEK293_Human1.44888612
48TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44795995
49SCL_19346495_ChIP-Seq_HPC-7_Human1.43408820
50* SPI1_23547873_ChIP-Seq_NB4_Human1.42434142
51* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42085370
52TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.41864874
53NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.41097042
54PU_27001747_Chip-Seq_BMDM_Mouse1.38418452
55RUNX1_22412390_ChIP-Seq_EML_Mouse1.38286758
56* VDR_24787735_ChIP-Seq_THP-1_Human1.36538048
57TCF7_22412390_ChIP-Seq_EML_Mouse1.36248831
58* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.35742580
59KDM2B_26808549_Chip-Seq_SUP-B15_Human1.31834308
60KDM2B_26808549_Chip-Seq_K562_Human1.31724191
61GATA2_21666600_ChIP-Seq_HMVEC_Human1.28872259
62SPI1_23127762_ChIP-Seq_K562_Human1.28794592
63GATA1_19941827_ChIP-Seq_MEL_Mouse1.27743819
64LXR_22292898_ChIP-Seq_THP-1_Human1.26927238
65* RUNX_20019798_ChIP-Seq_JUKART_Human1.25446190
66GATA1_19941826_ChIP-Seq_K562_Human1.24683649
67PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22263750
68* MYB_26560356_Chip-Seq_TH2_Human1.20943949
69E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.20528554
70ESR1_21235772_ChIP-Seq_MCF-7_Human1.15905604
71FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.13857201
72* KDM2B_26808549_Chip-Seq_JURKAT_Human1.12714596
73GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12383624
74KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11579917
75RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11259875
76MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.10830974
77ESR2_21235772_ChIP-Seq_MCF-7_Human1.10814505
78CTCF_27219007_Chip-Seq_ERYTHROID_Human1.10711846
79P63_26484246_Chip-Seq_KERATINOCYTES_Human1.10138366
80GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.08048007
81* UTX_26944678_Chip-Seq_JUKART_Human1.07827123
82EGR1_19032775_ChIP-ChIP_M12_Human1.07208597
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.06256956
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06233059
85TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06127423
86PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05769934
87* MYB_26560356_Chip-Seq_TH1_Human1.05497447
88NCOR1_26117541_ChIP-Seq_K562_Human1.04994011
89CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04398818
90KDM2B_26808549_Chip-Seq_DND41_Human1.03740477
91BCOR_27268052_Chip-Seq_Bcells_Human1.03719271
92GATA1_22025678_ChIP-Seq_K562_Human1.03516456
93SA1_27219007_Chip-Seq_ERYTHROID_Human1.03312016
94HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02874477
95* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02844710
96NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02297388
97BCL6_27268052_Chip-Seq_Bcells_Human1.01098819
98VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00333214
99SMAD_19615063_ChIP-ChIP_OVARY_Human0.99754446
100KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.99081485
101SOX2_20726797_ChIP-Seq_SW620_Human0.98042938
102* RACK7_27058665_Chip-Seq_MCF-7_Human0.97809345
103SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.97188718
104SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.97188718
105* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96220468
106CDX2_20551321_ChIP-Seq_CACO-2_Human0.95901602
107* ATF3_27146783_Chip-Seq_COLON_Human0.95494877
108* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94778222
109ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94207211
110KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.94127616
111MYC_22102868_ChIP-Seq_BL_Human0.93792012
112* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.93147773
113FOXO3_23340844_ChIP-Seq_DLD1_Human0.90969168
114PPAR_26484153_Chip-Seq_NCI-H1993_Human0.90589190
115* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90510756
116GATA2_22383799_ChIP-Seq_G1ME_Mouse0.89492544
117MAF_26560356_Chip-Seq_TH2_Human0.89410532
118KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.89291556
119* GATA2_19941826_ChIP-Seq_K562_Human0.88761346
120LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.88416536

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation3.66923700
2MP0003436_decreased_susceptibility_to3.41494928
3MP0003724_increased_susceptibility_to3.27379189
4MP0009840_abnormal_foam_cell3.20850237
5MP0003191_abnormal_cellular_cholesterol2.89510844
6MP0002419_abnormal_innate_immunity2.64892453
7MP0005058_abnormal_lysosome_morphology2.63222756
8MP0001835_abnormal_antigen_presentation2.57158498
9MP0009785_altered_susceptibility_to2.55937304
10MP0002139_abnormal_hepatobiliary_system2.24866041
11MP0006082_CNS_inflammation2.21227540
12MP0005000_abnormal_immune_tolerance2.18497091
13MP0005387_immune_system_phenotype2.18053385
14MP0001790_abnormal_immune_system2.18053385
15* MP0005025_abnormal_response_to2.15084787
16* MP0002148_abnormal_hypersensitivity_rea2.07745450
17MP0003300_gastrointestinal_ulcer2.06080713
18MP0001533_abnormal_skeleton_physiology2.04048501
19MP0003705_abnormal_hypodermis_morpholog2.02867855
20MP0009278_abnormal_bone_marrow1.95646845
21MP0004947_skin_inflammation1.93703454
22MP0005360_urolithiasis1.92212275
23MP0000343_altered_response_to1.89984759
24* MP0002452_abnormal_antigen_presenting1.85444267
25MP0005464_abnormal_platelet_physiology1.85140008
26MP0008438_abnormal_cutaneous_collagen1.81751335
27MP0009764_decreased_sensitivity_to1.80157452
28MP0003075_altered_response_to1.80119394
29MP0002138_abnormal_hepatobiliary_system1.75432062
30MP0001800_abnormal_humoral_immune1.72321524
31* MP0002723_abnormal_immune_serum1.69449399
32MP0000685_abnormal_immune_system1.61350850
33* MP0008469_abnormal_protein_level1.58874836
34* MP0001845_abnormal_inflammatory_respons1.57321995
35MP0002405_respiratory_system_inflammati1.55128711
36MP0008004_abnormal_stomach_pH1.52917907
37MP0005085_abnormal_gallbladder_physiolo1.51536724
38* MP0001819_abnormal_immune_cell1.49541897
39* MP0002420_abnormal_adaptive_immunity1.48791459
40MP0005365_abnormal_bile_salt1.47285338
41MP0008260_abnormal_autophagy1.46652189
42MP0003806_abnormal_nucleotide_metabolis1.46639985
43MP0001853_heart_inflammation1.45361864
44MP0003172_abnormal_lysosome_physiology1.44835861
45* MP0003448_altered_tumor_morphology1.42358150
46MP0010329_abnormal_lipoprotein_level1.36755241
47MP0003566_abnormal_cell_adhesion1.36733087
48MP0003828_pulmonary_edema1.34734902
49MP0001851_eye_inflammation1.33924214
50MP0010155_abnormal_intestine_physiology1.33456331
51MP0005451_abnormal_body_composition1.31916424
52MP0001545_abnormal_hematopoietic_system1.28904549
53MP0005397_hematopoietic_system_phenotyp1.28904549
54* MP0002998_abnormal_bone_remodeling1.28722194
55MP0000858_altered_metastatic_potential1.27316824
56MP0003656_abnormal_erythrocyte_physiolo1.26545593
57MP0004782_abnormal_surfactant_physiolog1.26228949
58MP0008875_abnormal_xenobiotic_pharmacok1.23233988
59MP0005671_abnormal_response_to1.21107781
60* MP0003453_abnormal_keratinocyte_physiol1.20391592
61MP0002933_joint_inflammation1.20012014
62MP0005310_abnormal_salivary_gland1.19520368
63* MP0000609_abnormal_liver_physiology1.19410096
64MP0005166_decreased_susceptibility_to1.18991033
65MP0002332_abnormal_exercise_endurance1.18980758
66MP0005023_abnormal_wound_healing1.16133006
67MP0003195_calcinosis1.13618483
68MP0003011_delayed_dark_adaptation1.12984498
69MP0003091_abnormal_cell_migration1.11540158
70MP0005164_abnormal_response_to1.10435761
71* MP0005076_abnormal_cell_differentiation1.09713086
72* MP0004510_myositis1.09666422
73MP0005083_abnormal_biliary_tract1.08825835
74* MP0005390_skeleton_phenotype1.08738642
75MP0009763_increased_sensitivity_to1.08674266
76MP0000465_gastrointestinal_hemorrhage1.07011296
77MP0006054_spinal_hemorrhage1.04846557
78MP0002254_reproductive_system_inflammat1.04700459
79MP0003186_abnormal_redox_activity1.04666126
80MP0002877_abnormal_melanocyte_morpholog1.04359257
81MP0005319_abnormal_enzyme/_coenzyme1.04207940
82MP0005275_abnormal_skin_tensile1.00736733
83MP0002060_abnormal_skin_morphology1.00567676
84MP0003252_abnormal_bile_duct1.00517466
85MP0000604_amyloidosis0.99606091
86MP0004883_abnormal_blood_vessel0.99245304
87* MP0000716_abnormal_immune_system0.98278891
88MP0009333_abnormal_splenocyte_physiolog0.97645542
89MP0002166_altered_tumor_susceptibility0.97518408
90MP0003329_amyloid_beta_deposits0.96487369
91MP0005670_abnormal_white_adipose0.94189587
92MP0004858_abnormal_nervous_system0.93330616
93MP0001542_abnormal_bone_strength0.92261565
94MP0000249_abnormal_blood_vessel0.92243013
95MP0003279_aneurysm0.92221490
96MP0010352_gastrointestinal_tract_polyps0.91245882
97MP0002006_tumorigenesis0.89779856
98* MP0002118_abnormal_lipid_homeostasis0.87574941
99MP0004019_abnormal_vitamin_homeostasis0.87481716
100MP0005666_abnormal_adipose_tissue0.85154991
101MP0003690_abnormal_glial_cell0.84616873
102* MP0000689_abnormal_spleen_morphology0.83472819
103MP0001849_ear_inflammation0.82712962
104MP0002796_impaired_skin_barrier0.82664411
105MP0005165_increased_susceptibility_to0.81642482
106MP0001873_stomach_inflammation0.81075477
107* MP0002722_abnormal_immune_system0.80944536
108MP0003763_abnormal_thymus_physiology0.80916669
109MP0005167_abnormal_blood-brain_barrier0.80422316
110MP0004130_abnormal_muscle_cell0.80236857
111MP0000598_abnormal_liver_morphology0.79693117
112* MP0003795_abnormal_bone_structure0.79527854
113MP0005257_abnormal_intraocular_pressure0.78934938
114* MP0002429_abnormal_blood_cell0.78777844
115MP0009115_abnormal_fat_cell0.78604057
116MP0001958_emphysema0.78587221
117* MP0002398_abnormal_bone_marrow0.78514163
118MP0004185_abnormal_adipocyte_glucose0.77756767
119MP0005584_abnormal_enzyme/coenzyme_acti0.76666784
120MP0001663_abnormal_digestive_system0.74914513
121MP0002132_abnormal_respiratory_system0.74439156
122MP0003183_abnormal_peptide_metabolism0.74096674
123MP0004808_abnormal_hematopoietic_stem0.72875938
124MP0009765_abnormal_xenobiotic_induced0.72295257
125MP0008874_decreased_physiological_sensi0.71416932
126MP0004233_abnormal_muscle_weight0.66842367
127MP0000920_abnormal_myelination0.66505209

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.26679271
2Recurrent gram-negative bacterial infections (HP:0005420)6.18163478
3Recurrent abscess formation (HP:0002722)5.46851946
4Recurrent bacterial skin infections (HP:0005406)5.12287997
5Systemic lupus erythematosus (HP:0002725)4.52297110
6Joint hemorrhage (HP:0005261)4.20337602
7Abnormality of macrophages (HP:0004311)4.02495842
8Myocardial infarction (HP:0001658)3.84052331
9Vacuolated lymphocytes (HP:0001922)3.53261502
10Complement deficiency (HP:0004431)3.39862456
11Orchitis (HP:0100796)3.39678702
12Myositis (HP:0100614)3.39201802
13Gingivitis (HP:0000230)3.38186638
14Abnormality of complement system (HP:0005339)3.35940341
15Mediastinal lymphadenopathy (HP:0100721)3.35624656
16Elevated erythrocyte sedimentation rate (HP:0003565)3.34286982
17Increased cerebral lipofuscin (HP:0011813)3.33560556
18Recurrent skin infections (HP:0001581)3.29374670
19Glomerulonephritis (HP:0000099)3.28628839
20Deep venous thrombosis (HP:0002625)3.21726642
21Dysostosis multiplex (HP:0000943)3.21041965
22Xanthomatosis (HP:0000991)3.15290513
23Chronic obstructive pulmonary disease (HP:0006510)3.04658697
24Obstructive lung disease (HP:0006536)3.04658697
25Interstitial pulmonary disease (HP:0006530)3.03766294
26Axonal loss (HP:0003447)2.99810996
27Stomatitis (HP:0010280)2.99739454
28Amyloidosis (HP:0011034)2.99100923
29Peritonitis (HP:0002586)2.98568206
30Increased neuronal autofluorescent lipopigment (HP:0002074)2.95954661
31Urticaria (HP:0001025)2.89516260
32Recurrent fungal infections (HP:0002841)2.85596858
33Urinary glycosaminoglycan excretion (HP:0003541)2.76112892
34Mucopolysacchariduria (HP:0008155)2.76112892
35Disinhibition (HP:0000734)2.76090174
36Neurofibrillary tangles (HP:0002185)2.74070130
37Abnormality of monocarboxylic acid metabolism (HP:0010996)2.73104135
38Menorrhagia (HP:0000132)2.72953664
39Autoimmune thrombocytopenia (HP:0001973)2.69293572
40Nephritis (HP:0000123)2.68037166
41Gingival bleeding (HP:0000225)2.67027988
42Cellulitis (HP:0100658)2.65548481
43Spontaneous hematomas (HP:0007420)2.64770374
44Pustule (HP:0200039)2.62346430
45Periodontitis (HP:0000704)2.60359664
46Vertebral compression fractures (HP:0002953)2.59946944
47Nuclear cataract (HP:0100018)2.56764374
48Abnormality of the common coagulation pathway (HP:0010990)2.56483120
49Optic neuritis (HP:0100653)2.53529649
50Retrobulbar optic neuritis (HP:0100654)2.53529649
51Abnormality of mucopolysaccharide metabolism (HP:0011020)2.52443268
52Abnormality of polysaccharide metabolism (HP:0011012)2.52443268
53Abnormality of glycosaminoglycan metabolism (HP:0004371)2.52443268
54Thick nail (HP:0001805)2.51518139
55Prolonged partial thromboplastin time (HP:0003645)2.49647905
56Osteolytic defects of the phalanges of the hand (HP:0009771)2.48006568
57Osteolytic defects of the hand bones (HP:0009699)2.48006568
58Tetraparesis (HP:0002273)2.32207439
59Increased IgE level (HP:0003212)2.31770685
60Keratoconjunctivitis (HP:0001096)2.30450704
61Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.29241256
62Epistaxis (HP:0000421)2.27254937
63Abnormality of aromatic amino acid family metabolism (HP:0004338)2.26435530
64Mutism (HP:0002300)2.26291125
65Hematochezia (HP:0002573)2.25607378
66Vasculitis (HP:0002633)2.22394360
67Hypoalphalipoproteinemia (HP:0003233)2.20112478
68Arterial thrombosis (HP:0004420)2.19895675
69Cerebral inclusion bodies (HP:0100314)2.18456349
70Cerebral aneurysm (HP:0004944)2.17351765
71Abnormality of liposaccharide metabolism (HP:0010968)2.16494561
72Abnormality of glycosphingolipid metabolism (HP:0004343)2.16494561
73Abnormality of glycolipid metabolism (HP:0010969)2.16494561
74Abnormality of glutamine family amino acid metabolism (HP:0010902)2.16174075
75Petechiae (HP:0000967)2.15201594
76Premature rupture of membranes (HP:0001788)2.14794365
77Increased serum ferritin (HP:0003281)2.14663586
78Malnutrition (HP:0004395)2.13376503
79Neuronal loss in central nervous system (HP:0002529)2.12979940
80Distal lower limb muscle weakness (HP:0009053)2.09294628
81Osteomyelitis (HP:0002754)2.06836086
82Pulmonary embolism (HP:0002204)2.04727023
83Abnormality of iron homeostasis (HP:0011031)2.04650999
84Hyperlipoproteinemia (HP:0010980)2.03340410
85Intrahepatic cholestasis (HP:0001406)2.02814087
86Bone pain (HP:0002653)2.01569362
87Esophageal varix (HP:0002040)2.00938764
88Episodic fever (HP:0001954)2.00704997
89Mitral stenosis (HP:0001718)2.00391375
90Gangrene (HP:0100758)1.99907381
91Segmental peripheral demyelination/remyelination (HP:0003481)1.97091070
92Anorexia (HP:0002039)1.96884786
93Progressive neurologic deterioration (HP:0002344)1.96856137
94Recurrent cutaneous fungal infections (HP:0011370)1.95753089
95Chronic mucocutaneous candidiasis (HP:0002728)1.95753089
96Hydroxyprolinuria (HP:0003080)1.95541466
97Abnormality of proline metabolism (HP:0010907)1.95541466
98Pathologic fracture (HP:0002756)1.95528033
99Hypertriglyceridemia (HP:0002155)1.95356980
100Meningitis (HP:0001287)1.93978520
101Upper motor neuron abnormality (HP:0002127)1.93030349
102Purpura (HP:0000979)1.92935380
103Chronic otitis media (HP:0000389)1.91671942
104Loss of speech (HP:0002371)1.91204365
105Abnormality of the nasal mucosa (HP:0000433)1.89988783
106Hemoptysis (HP:0002105)1.89913284
107Gastrointestinal infarctions (HP:0005244)1.89145338
108Epidermoid cyst (HP:0200040)1.86925645
109Hepatosplenomegaly (HP:0001433)1.85802136
110Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.85443573
111Pulmonary infiltrates (HP:0002113)1.85128901
112Increased connective tissue (HP:0009025)1.85002498
113Polycythemia (HP:0001901)1.83876358
114Asymmetric septal hypertrophy (HP:0001670)1.83819843
115Diminished motivation (HP:0000745)1.83422148
116Leukocytosis (HP:0001974)1.82893279
117Keratoconjunctivitis sicca (HP:0001097)1.82445542
118Thoracic kyphosis (HP:0002942)1.82402561
119Achilles tendon contracture (HP:0001771)1.81065840
120Apathy (HP:0000741)1.80529281
121Acne (HP:0001061)1.80473374
122Abnormality of transition element cation homeostasis (HP:0011030)1.80397644
123Nasal polyposis (HP:0100582)1.79950773
124Abnormality of the vasculature of the conjunctiva (HP:0008054)1.79665947
125Recurrent viral infections (HP:0004429)1.78506944
126Thin bony cortex (HP:0002753)1.78496541
127Polyneuropathy (HP:0001271)1.74991091
128Spondylolisthesis (HP:0003302)1.74582336
129Hypergammaglobulinemia (HP:0010702)1.71996107
130Prolonged bleeding time (HP:0003010)1.71798653
131Encephalitis (HP:0002383)1.70783895
132Premature loss of primary teeth (HP:0006323)1.70264824
133Abnormality of the endocardium (HP:0004306)1.69000813

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.21628026
2MAP4K13.18317857
3TBK13.13467028
4PRPF4B2.97519042
5MAP3K142.91344844
6BLK2.87255524
7IRAK32.72966051
8EPHB12.49301230
9TGFBR22.42743982
10TYK22.34839990
11TRIB32.34288301
12TAOK12.25141167
13IRAK42.18907330
14IKBKE2.13236736
15CSK2.07285083
16RIPK42.01345649
17PIM21.86718697
18DDR21.81019219
19FGFR41.77361946
20IKBKB1.75237116
21PKN21.74639846
22KIT1.63442178
23PBK1.60687801
24EPHA31.57741063
25STK101.56975940
26FGR1.54044300
27JAK11.52646076
28BMX1.51516651
29TAOK31.48853880
30MAP2K31.41531511
31CDC42BPA1.37960970
32MAP3K31.37625465
33JAK31.34838464
34NME21.30742538
35PIM11.23179345
36IRAK21.22249163
37ZAP701.22048468
38MAP3K111.21407605
39TTN1.20994919
40HCK1.20516968
41FES1.18641122
42JAK21.18088965
43PTK61.16699950
44MST1R1.16537411
45SIK11.12868989
46RIPK11.11856977
47NEK91.07727561
48RPS6KA41.05282329
49BTK1.02369427
50CSF1R1.01390987
51CHUK0.99992181
52MOS0.99681723
53MATK0.99369674
54CAMK1D0.97159462
55TXK0.93008613
56CDK60.92836529
57SMG10.92669592
58MAP2K20.89940520
59LRRK20.86215090
60CLK10.85741656
61ICK0.85510771
62MST40.84515661
63PAK40.84387198
64TNK20.83424297
65MAP3K100.82978022
66TRPM70.82020834
67PDPK10.81875293
68MAPK150.81844827
69PRKD20.80913957
70ARAF0.80206523
71TESK10.79908455
72MAP3K10.77490138
73MARK20.77214163
74FGFR30.76849134
75TEC0.76763040
76SIK30.76158298
77MARK30.75002563
78PDGFRA0.73575659
79MAP3K130.73567251
80BMPR20.73409828
81LCK0.72860805
82LYN0.72492389
83TESK20.71561914
84MAP3K60.71233857
85GRK60.70949300
86IRAK10.67437841
87SYK0.66271669
88MAPK120.64594972
89BCKDK0.64445611
90DAPK30.63884983
91LATS20.62660480
92EGFR0.59614021
93KDR0.59419511
94FLT30.58989872
95GSK3A0.58141004
96MAPK70.57668271
97MAPKAPK20.57423421
98NLK0.56775591
99PDK10.56250561
100GRK70.56228899
101RPS6KA20.53718803
102MAP2K60.53369771
103EIF2AK20.52255249
104MAP3K50.51258175
105PDGFRB0.50810799
106* ABL10.48673153
107PRKCD0.47733674
108DYRK1B0.45735004
109DAPK20.44687104
110PIK3CG0.44529509
111DMPK0.43521742
112EPHA20.43203851
113PRKG20.40900383
114ERBB40.40099108
115* ABL20.39400434
116KSR20.36994885
117MAPK110.36816314
118CDK90.35595016
119ITK0.35186104
120PTK20.34969191
121HIPK20.34617061
122DYRK30.33873269
123* RPS6KL10.33147678
124* RPS6KC10.33147678
125MAP3K80.33030449
126TAOK20.32590438
127ALK0.30455572
128* RPS6KA60.30106655
129CAMK1G0.29952864
130* MAPK40.29741744
131PRKAA20.29637560
132MTOR0.26699980
133FYN0.26549024

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051504.18564574
2Leishmaniasis_Homo sapiens_hsa051403.01352792
3Complement and coagulation cascades_Homo sapiens_hsa046102.75896473
4Malaria_Homo sapiens_hsa051442.36066085
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.33449796
6Osteoclast differentiation_Homo sapiens_hsa043802.32589432
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.12237927
8Legionellosis_Homo sapiens_hsa051342.11186677
9Pertussis_Homo sapiens_hsa051332.06433896
10Lysosome_Homo sapiens_hsa041421.83466064
11Arginine biosynthesis_Homo sapiens_hsa002201.82044328
12* Tuberculosis_Homo sapiens_hsa051521.78304795
13NF-kappa B signaling pathway_Homo sapiens_hsa040641.75451392
14Glycosaminoglycan degradation_Homo sapiens_hsa005311.70313404
15Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.70265810
16Pentose and glucuronate interconversions_Homo sapiens_hsa000401.65045849
17Caffeine metabolism_Homo sapiens_hsa002321.64726261
18Other glycan degradation_Homo sapiens_hsa005111.60583746
19NOD-like receptor signaling pathway_Homo sapiens_hsa046211.50030554
20Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.47862230
21Rheumatoid arthritis_Homo sapiens_hsa053231.46278931
22Nitrogen metabolism_Homo sapiens_hsa009101.45876544
23Phagosome_Homo sapiens_hsa041451.43571467
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.40114615
25* TNF signaling pathway_Homo sapiens_hsa046681.39637015
26Toxoplasmosis_Homo sapiens_hsa051451.36051281
27B cell receptor signaling pathway_Homo sapiens_hsa046621.34443730
28Salmonella infection_Homo sapiens_hsa051321.31965102
29Measles_Homo sapiens_hsa051621.30264593
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.29793209
31Autoimmune thyroid disease_Homo sapiens_hsa053201.29480541
32PPAR signaling pathway_Homo sapiens_hsa033201.27774277
33Influenza A_Homo sapiens_hsa051641.19230220
34Amoebiasis_Homo sapiens_hsa051461.15562494
35Histidine metabolism_Homo sapiens_hsa003401.12248376
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.11814955
37Fatty acid degradation_Homo sapiens_hsa000711.10901625
38Shigellosis_Homo sapiens_hsa051311.10362716
39Acute myeloid leukemia_Homo sapiens_hsa052211.09263382
40Apoptosis_Homo sapiens_hsa042101.07371301
41Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05122512
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.04635026
43Graft-versus-host disease_Homo sapiens_hsa053321.03261947
44Jak-STAT signaling pathway_Homo sapiens_hsa046301.01641515
45AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.01615329
46VEGF signaling pathway_Homo sapiens_hsa043701.01327602
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.00480371
48Hematopoietic cell lineage_Homo sapiens_hsa046400.99680129
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99584649
50Type I diabetes mellitus_Homo sapiens_hsa049400.98245409
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.97906100
52Adipocytokine signaling pathway_Homo sapiens_hsa049200.95655012
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94870956
54Intestinal immune network for IgA production_Homo sapiens_hsa046720.93974921
55Starch and sucrose metabolism_Homo sapiens_hsa005000.93356187
56Peroxisome_Homo sapiens_hsa041460.92351095
57Chemokine signaling pathway_Homo sapiens_hsa040620.87199073
58T cell receptor signaling pathway_Homo sapiens_hsa046600.86554185
59Hepatitis C_Homo sapiens_hsa051600.85625798
60Hepatitis B_Homo sapiens_hsa051610.85164469
61Tryptophan metabolism_Homo sapiens_hsa003800.84869587
62Prion diseases_Homo sapiens_hsa050200.83301796
63Herpes simplex infection_Homo sapiens_hsa051680.82023800
64Antigen processing and presentation_Homo sapiens_hsa046120.81918105
65Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81260643
66Chemical carcinogenesis_Homo sapiens_hsa052040.78636972
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.76815016
68African trypanosomiasis_Homo sapiens_hsa051430.76483994
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75249971
70Notch signaling pathway_Homo sapiens_hsa043300.75139581
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73598006
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72542493
73Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72031863
74Galactose metabolism_Homo sapiens_hsa000520.71035961
75Chronic myeloid leukemia_Homo sapiens_hsa052200.70865305
76Asthma_Homo sapiens_hsa053100.70412686
77Sulfur relay system_Homo sapiens_hsa041220.70327111
78ABC transporters_Homo sapiens_hsa020100.70216584
79Renal cell carcinoma_Homo sapiens_hsa052110.68773793
80Insulin resistance_Homo sapiens_hsa049310.68266669
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.67926467
82beta-Alanine metabolism_Homo sapiens_hsa004100.67820693
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67063987
84Pancreatic cancer_Homo sapiens_hsa052120.63084555
85Collecting duct acid secretion_Homo sapiens_hsa049660.62525855
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62203729
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61144750
88Retinol metabolism_Homo sapiens_hsa008300.60679305
89Endocytosis_Homo sapiens_hsa041440.59054586
90Folate biosynthesis_Homo sapiens_hsa007900.58694464
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57845434
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.57270884
93Phenylalanine metabolism_Homo sapiens_hsa003600.57260889
94Fructose and mannose metabolism_Homo sapiens_hsa000510.56207696
95Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55866829
96Non-small cell lung cancer_Homo sapiens_hsa052230.55745921
97Bladder cancer_Homo sapiens_hsa052190.55672153
98GnRH signaling pathway_Homo sapiens_hsa049120.53822967
99Sphingolipid metabolism_Homo sapiens_hsa006000.53522602
100Platelet activation_Homo sapiens_hsa046110.53436156
101Steroid hormone biosynthesis_Homo sapiens_hsa001400.53101077
102Fatty acid metabolism_Homo sapiens_hsa012120.52882545
103Pentose phosphate pathway_Homo sapiens_hsa000300.51973648
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51904531
105Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51192694
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50751616
107Phospholipase D signaling pathway_Homo sapiens_hsa040720.50374872
108HTLV-I infection_Homo sapiens_hsa051660.47590048
109Vibrio cholerae infection_Homo sapiens_hsa051100.46858145
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46380928
111Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46176279
112Epstein-Barr virus infection_Homo sapiens_hsa051690.46081185
113Mineral absorption_Homo sapiens_hsa049780.45861004
114Allograft rejection_Homo sapiens_hsa053300.44553770
115Primary immunodeficiency_Homo sapiens_hsa053400.44278106
116FoxO signaling pathway_Homo sapiens_hsa040680.43546133
117Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43197367
118Type II diabetes mellitus_Homo sapiens_hsa049300.42978217
119Insulin signaling pathway_Homo sapiens_hsa049100.42895902
120Viral myocarditis_Homo sapiens_hsa054160.42643599
121Fat digestion and absorption_Homo sapiens_hsa049750.42431103
122Proteoglycans in cancer_Homo sapiens_hsa052050.41178484
123mTOR signaling pathway_Homo sapiens_hsa041500.39928012
124MAPK signaling pathway_Homo sapiens_hsa040100.39489038
125HIF-1 signaling pathway_Homo sapiens_hsa040660.38718583
126Viral carcinogenesis_Homo sapiens_hsa052030.37837686
127Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37319264
128Prolactin signaling pathway_Homo sapiens_hsa049170.37227183
129Selenocompound metabolism_Homo sapiens_hsa004500.37001597
130Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.34391812
131Small cell lung cancer_Homo sapiens_hsa052220.32507580
132SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31636752
133Central carbon metabolism in cancer_Homo sapiens_hsa052300.30517389
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.28278758

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »