ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	leukocyte migration involved in inflammatory response (GO:0002523)	8.82598507
2	leukocyte aggregation (GO:0070486)	8.60756621
3	response to fungus (GO:0009620)	8.40623934
4	killing of cells of other organism (GO:0031640)	7.75770451
5	disruption of cells of other organism (GO:0044364)	7.75770451
6	sequestering of metal ion (GO:0051238)	7.30364996
7	neutrophil mediated immunity (GO:0002446)	6.86713716
8	response to peptidoglycan (GO:0032494)	6.78321500
9	respiratory burst (GO:0045730)	6.20490504
10	pentose-phosphate shunt (GO:0006098)	5.67206016
11	modulation of growth of symbiont involved in interaction with host (GO:0044144)	5.47460804
12	regulation of growth of symbiont in host (GO:0044126)	5.47460804
13	negative regulation of growth of symbiont in host (GO:0044130)	5.47460804
14	negative regulation of growth of symbiont involved in interaction with host (GO:0044146)	5.47460804
15	negative regulation of phagocytosis (GO:0050765)	5.45712046
16	reactive oxygen species biosynthetic process (GO:1903409)	5.36433592
17	myeloid leukocyte mediated immunity (GO:0002444)	5.27264833
18	NADPH regeneration (GO:0006740)	5.19644066
19	neutrophil activation involved in immune response (GO:0002283)	5.08320634
20	negative regulation of interleukin-8 production (GO:0032717)	5.05689584
21	positive regulation of gamma-delta T cell activation (GO:0046645)	4.96551402
22	microglial cell activation (GO:0001774)	4.82890467
23	positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)	4.73496214
24	cellular extravasation (GO:0045123)	4.66927755
25	chronic inflammatory response (GO:0002544)	4.60231238
26	Arp2/3 complex-mediated actin nucleation (GO:0034314)	4.42769631
27	hydrogen peroxide biosynthetic process (GO:0050665)	4.33674749
28	cell killing (GO:0001906)	4.21945871
29	negative regulation of erythrocyte differentiation (GO:0045647)	4.19400629
30	neutrophil activation (GO:0042119)	4.15880644
31	superoxide anion generation (GO:0042554)	4.11805592
32	modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0	4.09460218
33	positive regulation by organism of defense response of other organism involved in symbiotic interact	4.09460218
34	modulation by symbiont of host immune response (GO:0052553)	4.09460218
35	positive regulation by symbiont of host defense response (GO:0052509)	4.09460218
36	modulation by symbiont of host defense response (GO:0052031)	4.09460218
37	modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00	4.09460218
38	leukocyte mediated cytotoxicity (GO:0001909)	4.08119701
39	regulation of chemokine biosynthetic process (GO:0045073)	4.06201264
40	leukotriene biosynthetic process (GO:0019370)	4.00716343
41	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G	3.99124508
42	leukotriene metabolic process (GO:0006691)	3.97445487
43	detection of bacterium (GO:0016045)	3.97229235
44	positive regulation of interleukin-8 biosynthetic process (GO:0045416)	3.95829370
45	production of molecular mediator involved in inflammatory response (GO:0002532)	3.91197577
46	pentose metabolic process (GO:0019321)	3.91006012
47	detection of external biotic stimulus (GO:0098581)	3.88023535
48	macrophage activation involved in immune response (GO:0002281)	3.84003433
49	glucose catabolic process (GO:0006007)	3.83495027
50	detection of other organism (GO:0098543)	3.78305002
51	macrophage activation (GO:0042116)	3.76744868
52	neutrophil chemotaxis (GO:0030593)	3.76593383
53	granulocyte activation (GO:0036230)	3.75553799
54	neutrophil migration (GO:1990266)	3.66081071
55	regulation of myeloid leukocyte mediated immunity (GO:0002886)	3.64422791
56	negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)	3.52489563
57	detection of biotic stimulus (GO:0009595)	3.46209019
58	regulation of leukocyte degranulation (GO:0043300)	3.44616740
59	regulation of MHC class II biosynthetic process (GO:0045346)	3.40559469
60	negative regulation of interleukin-6 production (GO:0032715)	3.37654040
61	myeloid cell activation involved in immune response (GO:0002275)	3.35346419
62	regulation of gamma-delta T cell activation (GO:0046643)	3.34800363
63	negative regulation of cell killing (GO:0031342)	3.34726637
64	negative regulation of leukocyte mediated cytotoxicity (GO:0001911)	3.34726637
65	granulocyte migration (GO:0097530)	3.29640800
66	oxygen transport (GO:0015671)	3.25661093
67	phagosome maturation (GO:0090382)	3.18634325
68	negative regulation of lymphocyte mediated immunity (GO:0002707)	3.17629121
69	regulation of mast cell activation (GO:0033003)	3.16008316
70	actin nucleation (GO:0045010)	3.15301335
71	NADP metabolic process (GO:0006739)	3.14160050
72	interaction with symbiont (GO:0051702)	3.13162495
73	glucose 6-phosphate metabolic process (GO:0051156)	3.12228358
74	granulocyte chemotaxis (GO:0071621)	3.11912312
75	regulation of mast cell degranulation (GO:0043304)	3.09625489
76	positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)	3.08234131
77	regulation of gamma-delta T cell differentiation (GO:0045586)	3.06087343
78	regulation of regulated secretory pathway (GO:1903305)	3.05597824
79	positive regulation of myeloid leukocyte mediated immunity (GO:0002888)	3.05168659
80	modification by host of symbiont morphology or physiology (GO:0051851)	3.05141537
81	regulation of B cell receptor signaling pathway (GO:0050855)	3.03874777
82	leukocyte cell-cell adhesion (GO:0007159)	3.02877331
83	B cell receptor signaling pathway (GO:0050853)	2.99415818
84	regulation of tolerance induction (GO:0002643)	2.99146328
85	regulation of interferon-beta biosynthetic process (GO:0045357)	2.96095938
86	antigen processing and presentation of endogenous peptide antigen (GO:0002483)	2.94718856
87	antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)	2.94718856
88	response to muramyl dipeptide (GO:0032495)	2.93755726
89	positive regulation of mast cell activation (GO:0033005)	2.92581705
90	response to host immune response (GO:0052572)	2.91765802
91	response to immune response of other organism involved in symbiotic interaction (GO:0052564)	2.91765802
92	mannose metabolic process (GO:0006013)	2.91272640
93	innate immune response in mucosa (GO:0002227)	2.89771560
94	regulation of mast cell activation involved in immune response (GO:0033006)	2.89418798
95	lipopolysaccharide-mediated signaling pathway (GO:0031663)	2.88277655
96	detection of molecule of bacterial origin (GO:0032490)	2.87955296
97	cellular response to zinc ion (GO:0071294)	2.86087899
98	negative regulation of leukocyte mediated immunity (GO:0002704)	2.85859825
99	defense response to Gram-positive bacterium (GO:0050830)	2.85214455
100	positive regulation of chemokine biosynthetic process (GO:0045080)	2.85048080
101	positive regulation of lamellipodium assembly (GO:0010592)	2.85032588
102	positive regulation of B cell differentiation (GO:0045579)	2.84452772
103	positive regulation of regulated secretory pathway (GO:1903307)	2.81103834
104	regulation of tumor necrosis factor biosynthetic process (GO:0042534)	2.78684240
105	antibacterial humoral response (GO:0019731)	2.77396259
106	nucleobase-containing small molecule interconversion (GO:0015949)	2.77379450
107	imidazole-containing compound metabolic process (GO:0052803)	2.75560928
108	antimicrobial humoral response (GO:0019730)	2.73610020
109	response to zinc ion (GO:0010043)	2.73071160
110	negative regulation of interleukin-12 production (GO:0032695)	2.70878983
111	* macrophage differentiation (GO:0030225)	2.68897643
112	regulation of phagocytosis (GO:0050764)	2.66436326
113	positive regulation of mast cell activation involved in immune response (GO:0033008)	2.64464203
114	positive regulation of mast cell degranulation (GO:0043306)	2.64464203
115	3-UTR-mediated mRNA stabilization (GO:0070935)	2.62360063
116	leukocyte degranulation (GO:0043299)	2.59870080
117	response to defenses of other organism involved in symbiotic interaction (GO:0052173)	2.59773104
118	response to host (GO:0075136)	2.59773104
119	response to host defenses (GO:0052200)	2.59773104
120	mucosal immune response (GO:0002385)	2.58171532
121	regulation of hypersensitivity (GO:0002883)	2.58055341
122	regulation of interleukin-8 biosynthetic process (GO:0045414)	2.57963383
123	hydrogen peroxide metabolic process (GO:0042743)	2.57781818
124	DNA unwinding involved in DNA replication (GO:0006268)	2.51692881
125	immunoglobulin mediated immune response (GO:0016064)	2.51508896
126	regulation of B cell differentiation (GO:0045577)	2.46572823
127	* defense response to bacterium (GO:0042742)	2.45592269
128	negative regulation of myeloid cell apoptotic process (GO:0033033)	2.45261171
129	organ or tissue specific immune response (GO:0002251)	2.43068806
130	antigen processing and presentation of endogenous antigen (GO:0019883)	2.42233056
131	lipoxygenase pathway (GO:0019372)	2.42131674
132	homotypic cell-cell adhesion (GO:0034109)	2.40784683
133	killing of cells in other organism involved in symbiotic interaction (GO:0051883)	10.1064993
134	disruption of cells of other organism involved in symbiotic interaction (GO:0051818)	10.1064993
135	defense response to fungus (GO:0050832)	10.0379074

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	E2F7_22180533_ChIP-Seq_HELA_Human	6.64251079
2	MYB_21317192_ChIP-Seq_ERMYB_Mouse	4.26537380
3	MECOM_23826213_ChIP-Seq_KASUMI_Mouse	3.75122639
4	FOXM1_23109430_ChIP-Seq_U2OS_Human	3.57916915
5	VDR_21846776_ChIP-Seq_THP-1_Human	3.34083577
6	EGR1_19374776_ChIP-ChIP_THP-1_Human	3.29833098
7	IRF8_21731497_ChIP-ChIP_J774_Mouse	3.01435077
8	NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human	2.89666389
9	EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse	2.87514891
10	BRD4_27068464_Chip-Seq_AML-cells_Mouse	2.80697802
11	BP1_19119308_ChIP-ChIP_Hs578T_Human	2.58741949
12	* SPI1_23547873_ChIP-Seq_NB4_Human	2.55333072
13	ESR1_17901129_ChIP-ChIP_LIVER_Mouse	2.50056031
14	* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse	2.46774413
15	NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse	2.44270892
16	* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse	2.42510156
17	SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse	2.40458677
18	VDR_24763502_ChIP-Seq_THP-1_Human	2.34106125
19	E2F4_17652178_ChIP-ChIP_JURKAT_Human	2.33229163
20	MYC_22102868_ChIP-Seq_BL_Human	2.29138977
21	* SCL_19346495_ChIP-Seq_HPC-7_Human	2.26210461
22	SPI1_22096565_ChIP-ChIP_GC-B_Mouse	2.16997006
23	IRF8_27001747_Chip-Seq_BMDM_Mouse	2.08940135
24	RUNX1_22412390_ChIP-Seq_EML_Mouse	2.04197367
25	STAT6_20620947_ChIP-Seq_CD4_POS_T_Human	2.01171164
26	FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human	1.96545067
27	ELF1_17652178_ChIP-ChIP_JURKAT_Human	1.96442008
28	IRF8_22096565_ChIP-ChIP_GC-B_Human	1.91938350
29	UTX_26944678_Chip-Seq_JUKART_Human	1.88428359
30	FLI1_20887958_ChIP-Seq_HPC-7_Mouse	1.86851511
31	KDM2B_26808549_Chip-Seq_SUP-B15_Human	1.85912796
32	ASXL1_24218140_ChIP-Seq_BMDM_Mouse	1.84796891
33	IRF8_22096565_ChIP-ChIP_GC-B_Mouse	1.79113977
34	KDM2B_26808549_Chip-Seq_DND41_Human	1.75705276
35	MAF_26560356_Chip-Seq_TH1_Human	1.75330163
36	PPARG_19300518_ChIP-PET_3T3-L1_Mouse	1.74455104
37	MYB_26560356_Chip-Seq_TH2_Human	1.72855576
38	* TAL1_20887958_ChIP-Seq_HPC-7_Mouse	1.69474681
39	SFPI1_20887958_ChIP-Seq_HPC-7_Mouse	1.69411516
40	ESR1_15608294_ChIP-ChIP_MCF-7_Human	1.67959449
41	* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse	1.65049703
42	STAT4_19710469_ChIP-ChIP_TH1__Mouse	1.56902046
43	* TCF7_22412390_ChIP-Seq_EML_Mouse	1.54766975
44	CEBPA_23403033_ChIP-Seq_LIVER_Mouse	1.54394933
45	MYB_26560356_Chip-Seq_TH1_Human	1.53619571
46	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	1.53354861
47	* GATA1_22383799_ChIP-Seq_G1ME_Mouse	1.52596912
48	SPI1_23127762_ChIP-Seq_K562_Human	1.51276670
49	* LMO2_20887958_ChIP-Seq_HPC-7_Mouse	1.50904779
50	RUNX_20019798_ChIP-Seq_JUKART_Human	1.49272369
51	STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse	1.47927801
52	PPARA_22158963_ChIP-Seq_LIVER_Mouse	1.46444457
53	CEBPB_23403033_ChIP-Seq_LIVER_Mouse	1.44261559
54	VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human	1.43515016
55	* GATA2_22383799_ChIP-Seq_G1ME_Mouse	1.42723483
56	CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human	1.39551107
57	* HOXB4_20404135_ChIP-ChIP_EML_Mouse	1.38879827
58	* BCOR_27268052_Chip-Seq_Bcells_Human	1.38794420
59	RXR_22158963_ChIP-Seq_LIVER_Mouse	1.38292452
60	E2F1_21310950_ChIP-Seq_MCF-7_Human	1.37325208
61	GFI1B_20887958_ChIP-Seq_HPC-7_Mouse	1.36437274
62	AR_21909140_ChIP-Seq_LNCAP_Human	1.36111523
63	* GATA1_19941826_ChIP-Seq_K562_Human	1.33527134
64	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	1.32695320
65	STAT3_20064451_ChIP-Seq_CD4+T_Mouse	1.32177716
66	VDR_24787735_ChIP-Seq_THP-1_Human	1.32056833
67	E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human	1.30908575
68	GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human	1.29935740
69	PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse	1.28264123
70	ERG_20887958_ChIP-Seq_HPC-7_Mouse	1.27901877
71	PU.1_20513432_ChIP-Seq_Bcells_Mouse	1.27074405
72	TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.25692344
73	* PU_27001747_Chip-Seq_BMDM_Mouse	1.25138063
74	IRF1_21803131_ChIP-Seq_MONOCYTES_Human	1.24375733
75	P68_20966046_ChIP-Seq_HELA_Human	1.23229669
76	FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse	1.22872778
77	MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human	1.22451398
78	Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse	1.21973162
79	ELF1_20517297_ChIP-Seq_JURKAT_Human	1.20887210
80	FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse	1.20743908
81	* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse	1.20274799
82	CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse	1.19593689
83	GATA1_22025678_ChIP-Seq_K562_Human	1.18654342
84	EGR1_23403033_ChIP-Seq_LIVER_Mouse	1.18547770
85	TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse	1.18381249
86	* CTCF_27219007_Chip-Seq_ERYTHROID_Human	1.17899959
87	* NCOR1_26117541_ChIP-Seq_K562_Human	1.16948942
88	* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human	1.15318774
89	RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human	1.15245997
90	GATA1_19941827_ChIP-Seq_MEL_Mouse	1.13882069
91	MAF_26560356_Chip-Seq_TH2_Human	1.13873715
92	NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse	1.13372680
93	MYC_18555785_ChIP-Seq_MESCs_Mouse	1.10010706
94	SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse	1.08617293
95	* GATA2_20887958_ChIP-Seq_HPC-7_Mouse	1.08251250
96	* KDM2B_26808549_Chip-Seq_SIL-ALL_Human	1.07523897
97	SA1_27219007_Chip-Seq_ERYTHROID_Human	1.06290915
98	STAT6_21828071_ChIP-Seq_BEAS2B_Human	1.05607356
99	* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse	1.05565932
100	MYC_18358816_ChIP-ChIP_MESCs_Mouse	1.05081542
101	TFEB_21752829_ChIP-Seq_HELA_Human	1.04443153
102	RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human	1.03240086
103	FOXP3_21729870_ChIP-Seq_TREG_Human	1.01808115
104	* LYL1_20887958_ChIP-Seq_HPC-7_Mouse	1.01369659
105	KDM2B_26808549_Chip-Seq_JURKAT_Human	1.00660522
106	CREB1_15753290_ChIP-ChIP_HEK293T_Human	0.98561525
107	* GATA2_19941826_ChIP-Seq_K562_Human	0.98521547
108	EBNA2_21746931_ChIP-Seq_IB4-LCL_Human	0.96781388
109	* BCL6_27268052_Chip-Seq_Bcells_Human	0.96140218
110	SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human	0.95657028
111	GATA3_27048872_Chip-Seq_THYMUS_Human	0.95464816
112	E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human	0.94448637
113	* ELK3_25401928_ChIP-Seq_HUVEC_Human	0.94301763
114	EST1_17652178_ChIP-ChIP_JURKAT_Human	0.93873204
115	XRN2_22483619_ChIP-Seq_HELA_Human	0.93783955
116	FOXP3_17237761_ChIP-ChIP_TREG_Mouse	0.93522259
117	CIITA_25753668_ChIP-Seq_RAJI_Human	0.93233493
118	GATA3_26560356_Chip-Seq_TH2_Human	0.91368357
119	* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse	0.91254431
120	LXR_22292898_ChIP-Seq_THP-1_Human	0.90619529
121	PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse	0.90152877
122	* SPI1_20517297_ChIP-Seq_HL60_Human	0.89850641
123	KDM2B_26808549_Chip-Seq_HPB-ALL_Human	0.87570887

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0003436_decreased_susceptibility_to	4.63876936
2	MP0009785_altered_susceptibility_to	3.69722540
3	MP0003183_abnormal_peptide_metabolism	3.69698777
4	* MP0002419_abnormal_innate_immunity	3.34249056
5	MP0005464_abnormal_platelet_physiology	3.14983863
6	* MP0005025_abnormal_response_to	2.67979816
7	* MP0003303_peritoneal_inflammation	2.36336824
8	MP0002396_abnormal_hematopoietic_system	2.36307423
9	MP0000465_gastrointestinal_hemorrhage	2.36272025
10	MP0001835_abnormal_antigen_presentation	2.28938812
11	MP0003693_abnormal_embryo_hatching	2.28817711
12	MP0005000_abnormal_immune_tolerance	2.14302539
13	MP0003656_abnormal_erythrocyte_physiolo	2.13663598
14	MP0009278_abnormal_bone_marrow	2.11420043
15	MP0003300_gastrointestinal_ulcer	2.09429109
16	MP0005397_hematopoietic_system_phenotyp	2.05983053
17	MP0001545_abnormal_hematopoietic_system	2.05983053
18	* MP0002420_abnormal_adaptive_immunity	2.03159829
19	MP0001853_heart_inflammation	2.02516240
20	* MP0001819_abnormal_immune_cell	2.01143253
21	MP0002148_abnormal_hypersensitivity_rea	1.99456722
22	MP0000685_abnormal_immune_system	1.99100997
23	MP0002452_abnormal_antigen_presenting	1.98452464
24	MP0003172_abnormal_lysosome_physiology	1.97404241
25	MP0003191_abnormal_cellular_cholesterol	1.92271995
26	MP0000343_altered_response_to	1.92038136
27	MP0004808_abnormal_hematopoietic_stem	1.91786107
28	MP0001800_abnormal_humoral_immune	1.90765070
29	* MP0001533_abnormal_skeleton_physiology	1.88951899
30	MP0004147_increased_porphyrin_level	1.86176976
31	* MP0001845_abnormal_inflammatory_respons	1.84381035
32	MP0003724_increased_susceptibility_to	1.84177491
33	MP0002723_abnormal_immune_serum	1.84169730
34	MP0008260_abnormal_autophagy	1.77476324
35	* MP0002398_abnormal_bone_marrow	1.76835789
36	* MP0002405_respiratory_system_inflammati	1.76740578
37	MP0005360_urolithiasis	1.73577580
38	MP0002132_abnormal_respiratory_system	1.73568041
39	MP0009840_abnormal_foam_cell	1.72803766
40	MP0003806_abnormal_nucleotide_metabolis	1.69542756
41	* MP0000716_abnormal_immune_system	1.65828883
42	MP0005058_abnormal_lysosome_morphology	1.62830336
43	MP0000858_altered_metastatic_potential	1.57798138
44	MP0008469_abnormal_protein_level	1.57554083
45	MP0003828_pulmonary_edema	1.55307280
46	MP0004185_abnormal_adipocyte_glucose	1.53881369
47	MP0000689_abnormal_spleen_morphology	1.52592430
48	MP0002166_altered_tumor_susceptibility	1.52494711
49	* MP0002429_abnormal_blood_cell	1.52300780
50	MP0005451_abnormal_body_composition	1.51187547
51	MP0005671_abnormal_response_to	1.50609717
52	MP0001790_abnormal_immune_system	1.48938235
53	MP0005387_immune_system_phenotype	1.48938235
54	MP0000015_abnormal_ear_pigmentation	1.47438968
55	MP0010307_abnormal_tumor_latency	1.47331006
56	* MP0002722_abnormal_immune_system	1.46680189
57	MP0010094_abnormal_chromosome_stability	1.43059377
58	MP0002139_abnormal_hepatobiliary_system	1.41209941
59	MP0003111_abnormal_nucleus_morphology	1.40721011
60	MP0005174_abnormal_tail_pigmentation	1.40235066
61	MP0000490_abnormal_crypts_of	1.36898090
62	MP0003075_altered_response_to	1.36175972
63	MP0005075_abnormal_melanosome_morpholog	1.31801972
64	MP0009764_decreased_sensitivity_to	1.27454857
65	MP0010329_abnormal_lipoprotein_level	1.26799157
66	MP0001873_stomach_inflammation	1.26396740
67	MP0003186_abnormal_redox_activity	1.25910705
68	MP0001764_abnormal_homeostasis	1.25546569
69	MP0005365_abnormal_bile_salt	1.24737747
70	MP0003566_abnormal_cell_adhesion	1.23574285
71	MP0008057_abnormal_DNA_replication	1.21874458
72	* MP0010155_abnormal_intestine_physiology	1.20853899
73	MP0005085_abnormal_gallbladder_physiolo	1.17231990
74	MP0009763_increased_sensitivity_to	1.13846458
75	MP0005023_abnormal_wound_healing	1.13784141
76	MP0005076_abnormal_cell_differentiation	1.12969025
77	MP0002006_tumorigenesis	1.11299511
78	MP0009333_abnormal_splenocyte_physiolog	1.08141958
79	MP0003077_abnormal_cell_cycle	1.08124308
80	MP0005310_abnormal_salivary_gland	1.07099691
81	MP0004947_skin_inflammation	1.04401867
82	MP0008875_abnormal_xenobiotic_pharmacok	1.00026468
83	MP0002019_abnormal_tumor_incidence	0.99845688
84	MP0005083_abnormal_biliary_tract	0.98639610
85	MP0002998_abnormal_bone_remodeling	0.97796784
86	MP0005319_abnormal_enzyme/_coenzyme	0.97674746
87	MP0004883_abnormal_blood_vessel	0.97272904
88	MP0000609_abnormal_liver_physiology	0.96743539
89	MP0002009_preneoplasia	0.96534549
90	MP0000703_abnormal_thymus_morphology	0.96443411
91	MP0004381_abnormal_hair_follicle	0.94511821
92	MP0004957_abnormal_blastocyst_morpholog	0.94110820
93	MP0001986_abnormal_taste_sensitivity	0.92055932
94	* MP0001851_eye_inflammation	0.91714007
95	MP0002933_joint_inflammation	0.91397920
96	MP0003448_altered_tumor_morphology	0.88967103
97	MP0004130_abnormal_muscle_cell	0.88895513
98	MP0005164_abnormal_response_to	0.87531943
99	MP0002837_dystrophic_cardiac_calcinosis	0.86926313
100	MP0002877_abnormal_melanocyte_morpholog	0.85932311
101	MP0002277_abnormal_respiratory_mucosa	0.85023303
102	MP0003221_abnormal_cardiomyocyte_apopto	0.81463683
103	MP0003763_abnormal_thymus_physiology	0.81176527
104	MP0000598_abnormal_liver_morphology	0.80814387
105	MP0005584_abnormal_enzyme/coenzyme_acti	0.80190069
106	MP0008873_increased_physiological_sensi	0.78520671
107	* MP0005390_skeleton_phenotype	0.77398851
108	MP0005166_decreased_susceptibility_to	0.76844664
109	MP0005167_abnormal_blood-brain_barrier	0.76717605
110	MP0000249_abnormal_blood_vessel	0.76564461
111	MP0003866_abnormal_defecation	0.75722691
112	MP0002089_abnormal_postnatal_growth/wei	0.75477651
113	MP0009765_abnormal_xenobiotic_induced	0.72842959
114	MP0010352_gastrointestinal_tract_polyps	0.71901576
115	MP0003123_paternal_imprinting	0.71561640
116	MP0006082_CNS_inflammation	0.69944178
117	MP0000313_abnormal_cell_death	0.69202805
118	MP0000604_amyloidosis	0.68623386
119	MP0008874_decreased_physiological_sensi	0.67744509
120	* MP0001663_abnormal_digestive_system	0.63558597
121	MP0003690_abnormal_glial_cell	0.63471727
122	MP0006036_abnormal_mitochondrial_physio	0.61406570
123	MP0005666_abnormal_adipose_tissue	0.61224320
124	* MP0003795_abnormal_bone_structure	0.60501887
125	MP0005376_homeostasis/metabolism_phenot	0.58010314
126	MP0006035_abnormal_mitochondrial_morpho	0.55111066

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Eczematoid dermatitis (HP:0000976)	8.53147117
2	Recurrent abscess formation (HP:0002722)	8.12449182
3	Recurrent gram-negative bacterial infections (HP:0005420)	7.95427197
4	Recurrent bacterial skin infections (HP:0005406)	7.31878456
5	Chronic obstructive pulmonary disease (HP:0006510)	6.02634971
6	Obstructive lung disease (HP:0006536)	6.02634971
7	Hypochromic microcytic anemia (HP:0004840)	5.03061805
8	Mediastinal lymphadenopathy (HP:0100721)	4.85888908
9	Abnormality of macrophages (HP:0004311)	4.85633828
10	Recurrent skin infections (HP:0001581)	4.55698618
11	Gingivitis (HP:0000230)	4.55561623
12	Recurrent fungal infections (HP:0002841)	4.33658834
13	Cellulitis (HP:0100658)	4.06378217
14	Urticaria (HP:0001025)	3.98564062
15	Abnormality of the heme biosynthetic pathway (HP:0010472)	3.90467015
16	Meningitis (HP:0001287)	3.88601719
17	Thrombocytosis (HP:0001894)	3.73182653
18	Stomatitis (HP:0010280)	3.68970967
19	Increased cerebral lipofuscin (HP:0011813)	3.42373643
20	Papilledema (HP:0001085)	3.40531153
21	Loss of speech (HP:0002371)	3.33166277
22	Petechiae (HP:0000967)	3.29186156
23	Increased neuronal autofluorescent lipopigment (HP:0002074)	3.25048930
24	Retrobulbar optic neuritis (HP:0100654)	3.23701314
25	Optic neuritis (HP:0100653)	3.23701314
26	Microcytic anemia (HP:0001935)	3.17400875
27	Periodontitis (HP:0000704)	3.12497482
28	Myositis (HP:0100614)	3.02914074
29	Abnormal platelet volume (HP:0011876)	2.99525467
30	Chest pain (HP:0100749)	2.85394869
31	Panhypogammaglobulinemia (HP:0003139)	2.83181076
32	Keratoconjunctivitis sicca (HP:0001097)	2.82899297
33	IgM deficiency (HP:0002850)	2.82677690
34	Epistaxis (HP:0000421)	2.82116928
35	Abnormal platelet function (HP:0011869)	2.78365549
36	Impaired platelet aggregation (HP:0003540)	2.78365549
37	Abnormality of liposaccharide metabolism (HP:0010968)	2.77018584
38	Abnormality of glycosphingolipid metabolism (HP:0004343)	2.77018584
39	Abnormality of glycolipid metabolism (HP:0010969)	2.77018584
40	Osteomyelitis (HP:0002754)	2.76387861
41	Vacuolated lymphocytes (HP:0001922)	2.75572391
42	Chronic mucocutaneous candidiasis (HP:0002728)	2.75206293
43	Recurrent cutaneous fungal infections (HP:0011370)	2.75206293
44	Increased serum ferritin (HP:0003281)	2.69314795
45	Recurrent viral infections (HP:0004429)	2.68894804
46	Prolonged bleeding time (HP:0003010)	2.61194224
47	Chronic otitis media (HP:0000389)	2.60310289
48	Gingival bleeding (HP:0000225)	2.56488964
49	Keratoconjunctivitis (HP:0001096)	2.56148732
50	Abnormality of the prostate (HP:0008775)	2.53332483
51	Increased mean platelet volume (HP:0011877)	2.52570559
52	Elevated erythrocyte sedimentation rate (HP:0003565)	2.51400263
53	Sepsis (HP:0100806)	2.50900441
54	Eosinophilia (HP:0001880)	2.50869650
55	Granulocytopenia (HP:0001913)	2.48155269
56	Leukocytosis (HP:0001974)	2.45368519
57	Abnormality of mucopolysaccharide metabolism (HP:0011020)	2.43483224
58	Abnormality of polysaccharide metabolism (HP:0011012)	2.43483224
59	Abnormality of glycosaminoglycan metabolism (HP:0004371)	2.43483224
60	Hypergammaglobulinemia (HP:0010702)	2.41390216
61	Abnormal delayed hypersensitivity skin test (HP:0002963)	2.39841574
62	Agammaglobulinemia (HP:0004432)	2.39211637
63	Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)	2.38223990
64	Skin ulcer (HP:0200042)	2.36798474
65	Joint hemorrhage (HP:0005261)	2.31164718
66	Vasculitis (HP:0002633)	2.29868758
67	Thoracic kyphosis (HP:0002942)	2.28785324
68	Recurrent pneumonia (HP:0006532)	2.28340321
69	Hemoptysis (HP:0002105)	2.28073441
70	Abnormality of pyrimidine metabolism (HP:0004353)	2.26749930
71	Abnormality of T cell physiology (HP:0011840)	2.25819487
72	B lymphocytopenia (HP:0010976)	2.22805789
73	Abnormality of B cell number (HP:0010975)	2.22805789
74	Reticulocytopenia (HP:0001896)	2.22464026
75	Abnormality of the common coagulation pathway (HP:0010990)	2.20769701
76	Episodic fever (HP:0001954)	2.20726263
77	Abnormality of transition element cation homeostasis (HP:0011030)	2.18585345
78	Slow saccadic eye movements (HP:0000514)	2.17403350
79	Abnormality of the thoracic spine (HP:0100711)	2.16277251
80	Cutaneous melanoma (HP:0012056)	2.13667722
81	Menorrhagia (HP:0000132)	2.13209625
82	Deep venous thrombosis (HP:0002625)	2.13041116
83	Polycythemia (HP:0001901)	2.11637399
84	Amyloidosis (HP:0011034)	2.11616032
85	Abnormality of the fingertips (HP:0001211)	2.10364828
86	Interstitial pulmonary disease (HP:0006530)	2.08062877
87	Anorexia (HP:0002039)	2.07391848
88	Reduced antithrombin III activity (HP:0001976)	2.06033095
89	Acute lymphatic leukemia (HP:0006721)	2.05823306
90	Pulmonary embolism (HP:0002204)	2.04783262
91	Hypermelanotic macule (HP:0001034)	2.03671097
92	Neutropenia (HP:0001875)	2.02925115
93	Abnormality of T cells (HP:0002843)	2.02699613
94	Asymmetric septal hypertrophy (HP:0001670)	2.02193117
95	Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)	2.01455636
96	Thrombophlebitis (HP:0004418)	2.01391597
97	Pustule (HP:0200039)	2.01360370
98	Hypertriglyceridemia (HP:0002155)	2.00860118
99	Colitis (HP:0002583)	2.00733404
100	Disinhibition (HP:0000734)	1.99895684
101	Cutaneous photosensitivity (HP:0000992)	1.98000450
102	Hepatosplenomegaly (HP:0001433)	1.96348050
103	Spontaneous hematomas (HP:0007420)	1.96027854
104	Systemic lupus erythematosus (HP:0002725)	1.95495377
105	Hypochromic anemia (HP:0001931)	1.94129676
106	Gastrointestinal infarctions (HP:0005244)	1.91504277
107	Abnormality of the lumbar spine (HP:0100712)	1.91480547
108	Gangrene (HP:0100758)	1.89875924
109	Recurrent lower respiratory tract infections (HP:0002783)	1.89363940
110	Aplastic anemia (HP:0001915)	1.88741954
111	Myelodysplasia (HP:0002863)	1.88410357
112	Cheilitis (HP:0100825)	1.86939334
113	Dysostosis multiplex (HP:0000943)	1.86614521
114	Abnormality of eosinophils (HP:0001879)	1.86595413
115	Abnormality of cells of the lymphoid lineage (HP:0012140)	1.83810039
116	Purpura (HP:0000979)	1.82882350
117	Orchitis (HP:0100796)	1.82613261
118	Inflammation of the large intestine (HP:0002037)	1.80424999
119	Poikiloderma (HP:0001029)	1.80424681
120	Prolonged partial thromboplastin time (HP:0003645)	1.79861165
121	Gastrointestinal inflammation (HP:0004386)	1.79704087
122	Arterial thrombosis (HP:0004420)	1.79132624
123	Increased IgE level (HP:0003212)	1.79106068
124	Abnormality of the pleura (HP:0002103)	1.77295361
125	Lymphopenia (HP:0001888)	1.75774341
126	Encephalitis (HP:0002383)	1.75389876
127	Skin rash (HP:0000988)	1.75269226
128	Abnormal foot bone ossification (HP:0010675)	1.71373680
129	Abnormality of iron homeostasis (HP:0011031)	1.70271104
130	Autoimmune thrombocytopenia (HP:0001973)	1.69999618
131	Urinary glycosaminoglycan excretion (HP:0003541)	1.69638272
132	Mucopolysacchariduria (HP:0008155)	1.69638272
133	Increased density of long bones (HP:0006392)	1.67817976
134	Pulmonary infiltrates (HP:0002113)	1.66411631

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	IRAK4	5.14653645
2	TESK2	3.27350156
3	BLK	3.17980049
4	FES	2.86012703
5	EPHB1	2.66539212
6	GRK6	2.58860125
7	ERN1	2.42873476
8	BTK	2.41157564
9	MAP4K1	2.40486246
10	PRPF4B	2.35858433
11	MAP2K3	2.26860157
12	TESK1	2.25488499
13	TRPM7	2.23212422
14	RIPK4	2.21563660
15	PKN2	2.08056599
16	TAOK3	2.07470216
17	MAP3K12	2.06404881
18	WEE1	1.84887562
19	TEC	1.80132751
20	TRIB3	1.76298139
21	CLK1	1.72881308
22	STK10	1.66623348
23	CSK	1.65530569
24	CDK12	1.60447269
25	EEF2K	1.54831548
26	NEK2	1.51022213
27	PAK4	1.50008420
28	TTN	1.47792267
29	ZAP70	1.46761161
30	LRRK2	1.34395860
31	SYK	1.30381026
32	HCK	1.30253275
33	CDC7	1.29531145
34	TAOK2	1.29087761
35	SMG1	1.28034418
36	ERBB3	1.17619581
37	MAP2K4	1.14465087
38	MAP3K11	1.12150813
39	STK16	1.11399843
40	ALK	1.10822142
41	LIMK1	1.09880827
42	TYK2	1.07557928
43	PIM2	1.07427921
44	PIM1	1.06064935
45	KDR	1.05945271
46	TGFBR2	1.05346617
47	LATS1	1.04532697
48	MAP3K8	1.02601861
49	IRAK2	1.01973256
50	IRAK3	1.01323362
51	CSF1R	0.98463905
52	CDK19	0.94493486
53	EIF2AK3	0.92368495
54	KIT	0.91512731
55	BRSK2	0.91358872
56	CAMK1D	0.91003121
57	FGR	0.90647767
58	PTK6	0.90302405
59	FLT3	0.89641029
60	PDPK1	0.88507011
61	PRKG2	0.88430276
62	IRAK1	0.87427411
63	TAOK1	0.86903978
64	LYN	0.86476200
65	PDK1	0.84260414
66	MAP3K6	0.83849923
67	MAP3K13	0.81775766
68	BUB1	0.78183942
69	IKBKB	0.77689197
70	STK4	0.77597144
71	YES1	0.76513770
72	TBK1	0.75516722
73	RPS6KL1	0.75146537
74	RPS6KC1	0.75146537
75	SIK2	0.73960916
76	RPS6KA6	0.73758554
77	ITK	0.73312082
78	SCYL2	0.73123401
79	TXK	0.69904671
80	NUAK1	0.69444002
81	MARK3	0.69334405
82	JAK2	0.68711668
83	MAP3K14	0.65193237
84	PIK3CG	0.65077433
85	LCK	0.64473574
86	RPS6KA2	0.64121430
87	TNK2	0.61945149
88	BCKDK	0.61835746
89	CDK7	0.61686301
90	RAF1	0.60926927
91	TLK1	0.60303828
92	CDK4	0.58624377
93	ATR	0.57374739
94	MAP2K6	0.56567769
95	DAPK1	0.55622100
96	GRK7	0.54795793
97	ILK	0.54249426
98	MATK	0.52716599
99	MAPK12	0.52514832
100	* MAPK4	0.51906365
101	PRKCD	0.50368880
102	MAP3K3	0.49958109
103	MAP2K2	0.49899247
104	HIPK2	0.48712211
105	MAPK11	0.48694180
106	MARK2	0.47013936
107	STK11	0.44274319
108	RPS6KB2	0.43592566
109	PRKD2	0.42883864
110	ARAF	0.42355365
111	MAPKAPK2	0.40865975
112	ACVR1B	0.40787632
113	NEK9	0.40219827
114	CAMK1G	0.39891662
115	KSR2	0.39395471
116	MAP3K10	0.39192107
117	NEK1	0.38850280
118	PRKCQ	0.38498292
119	RPS6KA4	0.38276095
120	IKBKE	0.38246940
121	CDK6	0.38145633
122	RET	0.37714571
123	CAMKK2	0.36016346
124	MAP3K5	0.35265503
125	JAK3	0.32824550
126	FYN	0.32147764
127	MAPKAPK3	0.31337662
128	CDK3	0.31184499
129	CCNB1	0.30808422
130	JAK1	0.30212199
131	RPS6KA1	0.30134576
132	PAK1	0.29742315
133	MYLK	0.29450360
134	MAP3K1	0.29193900
135	BMX	0.29184056
136	MAPK7	0.28231030

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524	4.19885987
2	Leishmaniasis_Homo sapiens_hsa05140	3.53961939
3	Pentose phosphate pathway_Homo sapiens_hsa00030	2.88283056
4	Staphylococcus aureus infection_Homo sapiens_hsa05150	2.76956959
5	DNA replication_Homo sapiens_hsa03030	2.74143739
6	Asthma_Homo sapiens_hsa05310	2.50991390
7	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532	2.27982811
8	Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666	2.02667017
9	Leukocyte transendothelial migration_Homo sapiens_hsa04670	1.96971392
10	Osteoclast differentiation_Homo sapiens_hsa04380	1.95750143
11	Primary immunodeficiency_Homo sapiens_hsa05340	1.93794891
12	Starch and sucrose metabolism_Homo sapiens_hsa00500	1.77364574
13	Histidine metabolism_Homo sapiens_hsa00340	1.67231627
14	Other glycan degradation_Homo sapiens_hsa00511	1.64781926
15	Caffeine metabolism_Homo sapiens_hsa00232	1.62908160
16	Ascorbate and aldarate metabolism_Homo sapiens_hsa00053	1.59117607
17	African trypanosomiasis_Homo sapiens_hsa05143	1.57347504
18	Tuberculosis_Homo sapiens_hsa05152	1.52430631
19	B cell receptor signaling pathway_Homo sapiens_hsa04662	1.47861146
20	Graft-versus-host disease_Homo sapiens_hsa05332	1.46297367
21	Pertussis_Homo sapiens_hsa05133	1.44925061
22	Allograft rejection_Homo sapiens_hsa05330	1.42648939
23	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	1.42416506
24	Glutathione metabolism_Homo sapiens_hsa00480	1.39015127
25	Fc epsilon RI signaling pathway_Homo sapiens_hsa04664	1.38480899
26	Phagosome_Homo sapiens_hsa04145	1.37166081
27	Legionellosis_Homo sapiens_hsa05134	1.36074964
28	Primary bile acid biosynthesis_Homo sapiens_hsa00120	1.35596002
29	Shigellosis_Homo sapiens_hsa05131	1.33611225
30	T cell receptor signaling pathway_Homo sapiens_hsa04660	1.32860072
31	One carbon pool by folate_Homo sapiens_hsa00670	1.30905062
32	Autoimmune thyroid disease_Homo sapiens_hsa05320	1.29868233
33	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	1.25732350
34	Complement and coagulation cascades_Homo sapiens_hsa04610	1.24906950
35	Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650	1.19870246
36	Glycosaminoglycan degradation_Homo sapiens_hsa00531	1.18296909
37	NOD-like receptor signaling pathway_Homo sapiens_hsa04621	1.16144746
38	Platelet activation_Homo sapiens_hsa04611	1.14137118
39	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	1.13214211
40	Drug metabolism - other enzymes_Homo sapiens_hsa00983	1.12548094
41	Chemokine signaling pathway_Homo sapiens_hsa04062	1.08664949
42	Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321	1.08060513
43	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	1.07894726
44	Galactose metabolism_Homo sapiens_hsa00052	1.06888054
45	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	1.06695653
46	Carbon metabolism_Homo sapiens_hsa01200	1.06322318
47	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	1.01345153
48	Sulfur relay system_Homo sapiens_hsa04122	1.01134224
49	Biosynthesis of amino acids_Homo sapiens_hsa01230	1.01023302
50	Mismatch repair_Homo sapiens_hsa03430	1.00877519
51	Base excision repair_Homo sapiens_hsa03410	0.99737607
52	Toll-like receptor signaling pathway_Homo sapiens_hsa04620	0.97631471
53	ABC transporters_Homo sapiens_hsa02010	0.96393891
54	Acute myeloid leukemia_Homo sapiens_hsa05221	0.94528189
55	Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604	0.93593076
56	Other types of O-glycan biosynthesis_Homo sapiens_hsa00514	0.93159860
57	Intestinal immune network for IgA production_Homo sapiens_hsa04672	0.93032912
58	Homologous recombination_Homo sapiens_hsa03440	0.92827881
59	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.90628372
60	Cell cycle_Homo sapiens_hsa04110	0.89087073
61	RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622	0.87842761
62	Type I diabetes mellitus_Homo sapiens_hsa04940	0.87834671
63	Salmonella infection_Homo sapiens_hsa05132	0.87370324
64	Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623	0.86166790
65	Neurotrophin signaling pathway_Homo sapiens_hsa04722	0.84214029
66	NF-kappa B signaling pathway_Homo sapiens_hsa04064	0.83347367
67	Adipocytokine signaling pathway_Homo sapiens_hsa04920	0.81710000
68	Hepatitis C_Homo sapiens_hsa05160	0.81301245
69	Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142	0.80860915
70	Peroxisome_Homo sapiens_hsa04146	0.80126514
71	Lysosome_Homo sapiens_hsa04142	0.75974149
72	Toxoplasmosis_Homo sapiens_hsa05145	0.75268978
73	Herpes simplex infection_Homo sapiens_hsa05168	0.74889869
74	beta-Alanine metabolism_Homo sapiens_hsa00410	0.74511099
75	Apoptosis_Homo sapiens_hsa04210	0.74273444
76	Rheumatoid arthritis_Homo sapiens_hsa05323	0.73786784
77	Arginine biosynthesis_Homo sapiens_hsa00220	0.72179786
78	VEGF signaling pathway_Homo sapiens_hsa04370	0.71973324
79	Hepatitis B_Homo sapiens_hsa05161	0.71780778
80	Viral myocarditis_Homo sapiens_hsa05416	0.71747785
81	Carbohydrate digestion and absorption_Homo sapiens_hsa04973	0.71107935
82	Glycerophospholipid metabolism_Homo sapiens_hsa00564	0.71064948
83	Non-small cell lung cancer_Homo sapiens_hsa05223	0.69108017
84	Viral carcinogenesis_Homo sapiens_hsa05203	0.68471597
85	N-Glycan biosynthesis_Homo sapiens_hsa00510	0.68279402
86	Fructose and mannose metabolism_Homo sapiens_hsa00051	0.67743350
87	Notch signaling pathway_Homo sapiens_hsa04330	0.66422944
88	Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120	0.65769068
89	Ribosome_Homo sapiens_hsa03010	0.64493044
90	Sphingolipid signaling pathway_Homo sapiens_hsa04071	0.64434392
91	Epstein-Barr virus infection_Homo sapiens_hsa05169	0.63899563
92	Measles_Homo sapiens_hsa05162	0.62928759
93	Regulation of autophagy_Homo sapiens_hsa04140	0.62312962
94	Bladder cancer_Homo sapiens_hsa05219	0.61707989
95	Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533	0.61265704
96	Cyanoamino acid metabolism_Homo sapiens_hsa00460	0.61176608
97	Systemic lupus erythematosus_Homo sapiens_hsa05322	0.60606531
98	Selenocompound metabolism_Homo sapiens_hsa00450	0.60555217
99	Pancreatic cancer_Homo sapiens_hsa05212	0.60503566
100	Renal cell carcinoma_Homo sapiens_hsa05211	0.59786164
101	Choline metabolism in cancer_Homo sapiens_hsa05231	0.58619807
102	Chronic myeloid leukemia_Homo sapiens_hsa05220	0.57754439
103	HTLV-I infection_Homo sapiens_hsa05166	0.57604885
104	mTOR signaling pathway_Homo sapiens_hsa04150	0.57602648
105	GnRH signaling pathway_Homo sapiens_hsa04912	0.57520707
106	HIF-1 signaling pathway_Homo sapiens_hsa04066	0.56692207
107	Insulin resistance_Homo sapiens_hsa04931	0.56225031
108	Phenylalanine metabolism_Homo sapiens_hsa00360	0.55437917
109	AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933	0.54908806
110	* Transcriptional misregulation in cancer_Homo sapiens_hsa05202	0.54647403
111	Renin-angiotensin system_Homo sapiens_hsa04614	0.53972218
112	Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923	0.53666591
113	FoxO signaling pathway_Homo sapiens_hsa04068	0.51986938
114	Bacterial invasion of epithelial cells_Homo sapiens_hsa05100	0.51726725
115	Influenza A_Homo sapiens_hsa05164	0.50712481
116	Malaria_Homo sapiens_hsa05144	0.50520919
117	Colorectal cancer_Homo sapiens_hsa05210	0.49043848
118	Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750	0.48972286
119	Phosphatidylinositol signaling system_Homo sapiens_hsa04070	0.48662831
120	Prolactin signaling pathway_Homo sapiens_hsa04917	0.48332533
121	Fatty acid degradation_Homo sapiens_hsa00071	0.47218301
122	Antigen processing and presentation_Homo sapiens_hsa04612	0.47086664
123	TNF signaling pathway_Homo sapiens_hsa04668	0.46726368
124	Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060	0.46680669
125	Tryptophan metabolism_Homo sapiens_hsa00380	0.46380044
126	Jak-STAT signaling pathway_Homo sapiens_hsa04630	0.46372452
127	p53 signaling pathway_Homo sapiens_hsa04115	0.46267024
128	Phospholipase D signaling pathway_Homo sapiens_hsa04072	0.45394013
129	Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014	0.44971879
130	Fanconi anemia pathway_Homo sapiens_hsa03460	0.44251413
131	Amoebiasis_Homo sapiens_hsa05146	0.43844347
132	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	0.43453879
133	Cysteine and methionine metabolism_Homo sapiens_hsa00270	0.43072594
134	Endocytosis_Homo sapiens_hsa04144	0.42438273
135	Type II diabetes mellitus_Homo sapiens_hsa04930	0.42202217
136	Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760	0.42167176
137	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.42098847
138	Nitrogen metabolism_Homo sapiens_hsa00910	0.41532982
139	Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914	0.41138637
140	Inositol phosphate metabolism_Homo sapiens_hsa00562	0.40099487
141	Endometrial cancer_Homo sapiens_hsa05213	0.37616499

CEBPE

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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