CEBPZOS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.39516341
2energy coupled proton transport, down electrochemical gradient (GO:0015985)7.96877375
3ATP synthesis coupled proton transport (GO:0015986)7.96877375
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.57190713
5respiratory electron transport chain (GO:0022904)6.73228180
6electron transport chain (GO:0022900)6.56086252
7establishment of protein localization to mitochondrial membrane (GO:0090151)6.03961898
8chaperone-mediated protein transport (GO:0072321)5.54621278
9protein neddylation (GO:0045116)5.34155561
10behavioral response to nicotine (GO:0035095)5.27062264
11protein complex biogenesis (GO:0070271)5.22210373
12ribosomal small subunit biogenesis (GO:0042274)4.98049832
13mitochondrial respiratory chain complex I assembly (GO:0032981)4.97449152
14NADH dehydrogenase complex assembly (GO:0010257)4.97449152
15mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.97449152
16proteasome assembly (GO:0043248)4.79414754
17GTP biosynthetic process (GO:0006183)4.77865017
18viral transcription (GO:0019083)4.76953617
19mitochondrial respiratory chain complex assembly (GO:0033108)4.75412419
20translational termination (GO:0006415)4.60532508
21cotranslational protein targeting to membrane (GO:0006613)4.50867984
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.42719958
23protein targeting to ER (GO:0045047)4.40643039
24ribosomal small subunit assembly (GO:0000028)4.40481612
25transcription elongation from RNA polymerase III promoter (GO:0006385)4.34105942
26termination of RNA polymerase III transcription (GO:0006386)4.34105942
27oxidative phosphorylation (GO:0006119)4.29538276
28purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.29278749
29regulation of mitochondrial translation (GO:0070129)4.25839190
30protein localization to endoplasmic reticulum (GO:0070972)4.25806274
31water-soluble vitamin biosynthetic process (GO:0042364)4.22522782
32purine nucleoside triphosphate biosynthetic process (GO:0009145)4.21798036
33inner mitochondrial membrane organization (GO:0007007)4.19931197
34establishment of protein localization to endoplasmic reticulum (GO:0072599)4.17969071
35ATP biosynthetic process (GO:0006754)4.15396959
36regulation of posttranscriptional gene silencing (GO:0060147)4.15383986
37regulation of gene silencing by miRNA (GO:0060964)4.15383986
38regulation of gene silencing by RNA (GO:0060966)4.15383986
39hydrogen ion transmembrane transport (GO:1902600)4.13530497
40dopamine transport (GO:0015872)4.05162848
41UTP biosynthetic process (GO:0006228)4.05069013
42cullin deneddylation (GO:0010388)3.97225406
43maturation of SSU-rRNA (GO:0030490)3.91944624
44guanosine-containing compound biosynthetic process (GO:1901070)3.91128542
45establishment of protein localization to mitochondrion (GO:0072655)3.88419857
46translational elongation (GO:0006414)3.88369349
47regulation of cellular amino acid metabolic process (GO:0006521)3.87996182
48translation (GO:0006412)3.85949298
49protein targeting to mitochondrion (GO:0006626)3.83132276
50ribosomal large subunit biogenesis (GO:0042273)3.81188005
51respiratory chain complex IV assembly (GO:0008535)3.80308072
52cellular protein complex disassembly (GO:0043624)3.78201556
53viral life cycle (GO:0019058)3.74327283
54ribonucleoside triphosphate biosynthetic process (GO:0009201)3.73978862
557-methylguanosine mRNA capping (GO:0006370)3.69937148
56negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.69480841
57kynurenine metabolic process (GO:0070189)3.69207078
58proton transport (GO:0015992)3.67574664
59RNA capping (GO:0036260)3.67337439
607-methylguanosine RNA capping (GO:0009452)3.67337439
61protein deneddylation (GO:0000338)3.66199123
62hydrogen transport (GO:0006818)3.59028269
63protein localization to mitochondrion (GO:0070585)3.58778821
64UTP metabolic process (GO:0046051)3.57035258
65L-fucose metabolic process (GO:0042354)3.52078006
66L-fucose catabolic process (GO:0042355)3.52078006
67fucose catabolic process (GO:0019317)3.52078006
68cytochrome complex assembly (GO:0017004)3.51863473
69DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.46095844
70antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.44678638
71positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.40492427
72peptidyl-histidine modification (GO:0018202)3.38054843
73nucleoside diphosphate phosphorylation (GO:0006165)3.37817574
74intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.37440083
75signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.37440083
76membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.37313922
77cellular ketone body metabolic process (GO:0046950)3.36826314
78nucleoside triphosphate biosynthetic process (GO:0009142)3.35978216
79negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.35900646
80negative regulation of ligase activity (GO:0051352)3.35900646
81signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.35072554
82signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.35072554
83signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.35072554
84translational initiation (GO:0006413)3.33984223
85sulfation (GO:0051923)3.31241616
86cellular component biogenesis (GO:0044085)3.29105131
87tryptophan catabolic process (GO:0006569)3.29057332
88indole-containing compound catabolic process (GO:0042436)3.29057332
89indolalkylamine catabolic process (GO:0046218)3.29057332
90signal transduction involved in DNA integrity checkpoint (GO:0072401)3.26582472
91signal transduction involved in DNA damage checkpoint (GO:0072422)3.26582472
92maturation of 5.8S rRNA (GO:0000460)3.25866073
93intracellular protein transmembrane import (GO:0044743)3.23275871
94signal transduction involved in cell cycle checkpoint (GO:0072395)3.22685512
95L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.21881146
96CTP metabolic process (GO:0046036)3.20210040
97CTP biosynthetic process (GO:0006241)3.20210040
98nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.18989905
99establishment of integrated proviral latency (GO:0075713)3.18740632
100regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.18355557
101regulation of cellular amine metabolic process (GO:0033238)3.17685983
102antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.17549335
103transcription elongation from RNA polymerase I promoter (GO:0006362)3.12375582
104ATP hydrolysis coupled proton transport (GO:0015991)3.10198185
105energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.10198185
106establishment of viral latency (GO:0019043)3.09778684
107indolalkylamine metabolic process (GO:0006586)3.08427369
108mitochondrial transport (GO:0006839)3.06859924
109negative regulation of synaptic transmission, GABAergic (GO:0032229)3.05564734
110protein-cofactor linkage (GO:0018065)3.03689369
111cellular response to ATP (GO:0071318)3.03482060
112protein complex disassembly (GO:0043241)3.02285337
113anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.02098083
114rRNA modification (GO:0000154)3.01245598
115gamma-aminobutyric acid transport (GO:0015812)3.00524025
116aerobic respiration (GO:0009060)2.99766118
117kidney morphogenesis (GO:0060993)2.99357594
118regulation of oxidative phosphorylation (GO:0002082)2.97668982
119regulation of hexokinase activity (GO:1903299)2.97393788
120regulation of glucokinase activity (GO:0033131)2.97393788
121macromolecular complex disassembly (GO:0032984)2.96468197
122negative regulation of DNA-dependent DNA replication (GO:2000104)2.95532534
123transcription from RNA polymerase I promoter (GO:0006360)2.89268725
124DNA deamination (GO:0045006)2.87909840
125response to pheromone (GO:0019236)2.87850336
126pseudouridine synthesis (GO:0001522)2.87807816
127ketone body metabolic process (GO:1902224)2.80800841
128nephron epithelium morphogenesis (GO:0072088)2.78920567
129nephron tubule morphogenesis (GO:0072078)2.78920567
130regulation of hippo signaling (GO:0035330)2.78714924
131negative regulation of telomere maintenance (GO:0032205)2.78064814
132regulation of nuclear cell cycle DNA replication (GO:0033262)2.73880490
133regulation of action potential (GO:0098900)2.72144090
134tryptophan metabolic process (GO:0006568)2.69588446
135protein K6-linked ubiquitination (GO:0085020)2.67040777
136protein prenylation (GO:0018342)2.60455213
137prenylation (GO:0097354)2.60455213
138negative regulation of transcription regulatory region DNA binding (GO:2000678)2.58450221
139primary amino compound metabolic process (GO:1901160)2.57799790
140neuronal action potential (GO:0019228)2.56408334
141purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.56034437
1423-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.56034437
143negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.54201186
144negative regulation of translation, ncRNA-mediated (GO:0040033)2.54201186
145regulation of translation, ncRNA-mediated (GO:0045974)2.54201186
146regulation of DNA endoreduplication (GO:0032875)2.50131894
147indole-containing compound metabolic process (GO:0042430)2.49936003
148reflex (GO:0060004)2.48113245
149serotonin metabolic process (GO:0042428)2.47479614
150detection of light stimulus involved in sensory perception (GO:0050962)2.46180490
151detection of light stimulus involved in visual perception (GO:0050908)2.46180490
152regulation of skeletal muscle contraction (GO:0014819)2.45815961
153regulation of sequestering of triglyceride (GO:0010889)2.45703440
154platelet dense granule organization (GO:0060155)2.45406483
155membrane depolarization during action potential (GO:0086010)2.44957631
156protein import into peroxisome matrix (GO:0016558)2.44530633
157rRNA catabolic process (GO:0016075)2.43900333
158magnesium ion transport (GO:0015693)2.35290153
159preassembly of GPI anchor in ER membrane (GO:0016254)2.35204223
160amino acid salvage (GO:0043102)2.34866900
161L-methionine salvage (GO:0071267)2.34866900
162L-methionine biosynthetic process (GO:0071265)2.34866900
163positive regulation of action potential (GO:0045760)2.31867913
164calcium ion import (GO:0070509)2.30671473
165detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.29263727
166exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.27688892
167regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.27444218
168negative regulation of response to food (GO:0032096)2.27284341
169negative regulation of appetite (GO:0032099)2.27284341
170double-strand break repair via homologous recombination (GO:0000724)2.26802891
171recombinational repair (GO:0000725)2.26309971
172regulation of triglyceride biosynthetic process (GO:0010866)2.26308974
173positive regulation of fatty acid oxidation (GO:0046321)2.25977641
174replication fork processing (GO:0031297)2.25859859
175methionine biosynthetic process (GO:0009086)2.21734034
176piRNA metabolic process (GO:0034587)2.21419135

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.96166623
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.41000772
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.37620665
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.14637919
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.11273986
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.77656181
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.63028414
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.37614081
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.34179792
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.30514022
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.29204943
12ZNF274_21170338_ChIP-Seq_K562_Hela3.25334761
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.24150866
14CREB1_15753290_ChIP-ChIP_HEK293T_Human3.15947403
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.92241298
16PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.60048572
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.47442072
18SRF_21415370_ChIP-Seq_HL-1_Mouse2.43213587
19SALL1_21062744_ChIP-ChIP_HESCs_Human2.38466399
20RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.36364346
21MYC_18358816_ChIP-ChIP_MESCs_Mouse2.35885554
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.30619228
23ELK1_19687146_ChIP-ChIP_HELA_Human2.27440696
24VDR_23849224_ChIP-Seq_CD4+_Human2.24794691
25YY1_21170310_ChIP-Seq_MESCs_Mouse2.21410716
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.14530678
27ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.13135880
28DCP1A_22483619_ChIP-Seq_HELA_Human2.11556127
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.08626121
30E2F1_18555785_ChIP-Seq_MESCs_Mouse2.00654343
31MYC_19079543_ChIP-ChIP_MESCs_Mouse1.99304113
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.97944490
33VDR_22108803_ChIP-Seq_LS180_Human1.90990272
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.79164371
35ELK1_22589737_ChIP-Seq_MCF10A_Human1.76514576
36TTF2_22483619_ChIP-Seq_HELA_Human1.75575886
37FOXP3_21729870_ChIP-Seq_TREG_Human1.73737113
38TAF15_26573619_Chip-Seq_HEK293_Human1.63539935
39POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.62358652
40XRN2_22483619_ChIP-Seq_HELA_Human1.61294422
41CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59714208
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57198615
43CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.57135720
44HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54196319
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54039324
46IRF1_19129219_ChIP-ChIP_H3396_Human1.53406295
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50239785
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.49346662
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.48126820
50CBP_20019798_ChIP-Seq_JUKART_Human1.47235117
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.47235117
52UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.45697868
53POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43998353
54NELFA_20434984_ChIP-Seq_ESCs_Mouse1.43760782
55FUS_26573619_Chip-Seq_HEK293_Human1.41377716
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38609316
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.38252772
58STAT3_23295773_ChIP-Seq_U87_Human1.36687789
59TCF4_23295773_ChIP-Seq_U87_Human1.36432163
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36090375
61FOXA1_27270436_Chip-Seq_PROSTATE_Human1.35760552
62FOXA1_25329375_ChIP-Seq_VCAP_Human1.35760552
63TP53_22573176_ChIP-Seq_HFKS_Human1.35405678
64GABP_19822575_ChIP-Seq_HepG2_Human1.33128765
65SOX2_19829295_ChIP-Seq_ESCs_Human1.32791793
66NANOG_19829295_ChIP-Seq_ESCs_Human1.32791793
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.29712230
68ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29291701
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28610678
70ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.26988101
71SMAD4_21799915_ChIP-Seq_A2780_Human1.25876897
72FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.23584811
73AR_25329375_ChIP-Seq_VCAP_Human1.22996323
74GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22913685
75RNF2_27304074_Chip-Seq_NSC_Mouse1.21934850
76AR_21572438_ChIP-Seq_LNCaP_Human1.21658201
77SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19888732
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19605340
79AUTS2_25519132_ChIP-Seq_293T-REX_Human1.18221648
80PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17926250
81KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17807205
82MYC_18940864_ChIP-ChIP_HL60_Human1.17637012
83CBX2_27304074_Chip-Seq_ESCs_Mouse1.17345138
84CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.16899804
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16793958
86EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.16489388
87REST_21632747_ChIP-Seq_MESCs_Mouse1.16425059
88EZH2_27294783_Chip-Seq_NPCs_Mouse1.15589544
89NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15314350
90YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15226951
91MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.14469028
92EZH2_22144423_ChIP-Seq_EOC_Human1.14273909
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.13308975
94IGF1R_20145208_ChIP-Seq_DFB_Human1.12983280
95PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12090130
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.11156970
97CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.09759009
98NANOG_18555785_ChIP-Seq_MESCs_Mouse1.09631037
99KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09349542
100KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09349542
101KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09349542
102SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08765966
103HOXB7_26014856_ChIP-Seq_BT474_Human1.08225753
104PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06999555
105FOXA1_21572438_ChIP-Seq_LNCaP_Human1.06482390
106SOX17_20123909_ChIP-Seq_XEN_Mouse1.06017426
107BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05602420
108EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05302173
109CDX2_22108803_ChIP-Seq_LS180_Human1.05291616
110GATA3_21878914_ChIP-Seq_MCF-7_Human1.04897029
111AR_20517297_ChIP-Seq_VCAP_Human1.04703593
112NANOG_18555785_Chip-Seq_ESCs_Mouse1.03867633
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.03622801
114P53_22387025_ChIP-Seq_ESCs_Mouse1.03162581
115PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02034224
116CRX_20693478_ChIP-Seq_RETINA_Mouse1.01557436
117STAT3_18555785_Chip-Seq_ESCs_Mouse1.01520583
118POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01185534
119BCAT_22108803_ChIP-Seq_LS180_Human1.01024407
120RUNX2_22187159_ChIP-Seq_PCA_Human1.00918835
121GBX2_23144817_ChIP-Seq_PC3_Human1.00602733
122SMAD4_21741376_ChIP-Seq_EPCs_Human1.00377825
123JUN_21703547_ChIP-Seq_K562_Human1.00342904
124TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00168478
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99678442
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99678442
127PRDM14_20953172_ChIP-Seq_ESCs_Human0.99510584
128TCF4_22108803_ChIP-Seq_LS180_Human0.99430707
129FLI1_21867929_ChIP-Seq_TH2_Mouse0.99094592
130RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98380560
131CTBP1_25329375_ChIP-Seq_LNCAP_Human0.98092168
132CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.97107909
133KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96938970
134ER_23166858_ChIP-Seq_MCF-7_Human0.95802002
135SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93053731
136PCGF2_27294783_Chip-Seq_ESCs_Mouse0.91438221
137HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.91141057
138FLI1_27457419_Chip-Seq_LIVER_Mouse0.90667613
139FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90405961
140NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.90050706
141RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89964706
142POU3F2_20337985_ChIP-ChIP_501MEL_Human0.89717453
143EWS_26573619_Chip-Seq_HEK293_Human0.89716092
144SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87087060
145CTBP2_25329375_ChIP-Seq_LNCAP_Human0.85464858
146FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.83989102
147SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.83416560
148NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.82791998
149CTCF_18555785_ChIP-Seq_MESCs_Mouse0.82332315
150SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.81516835
151ERG_20887958_ChIP-Seq_HPC-7_Mouse0.80741704
152PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.80279970
153SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78892580
154POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78763355
155SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77861025
156HTT_18923047_ChIP-ChIP_STHdh_Human0.76723131
157P300_19829295_ChIP-Seq_ESCs_Human0.76631772
158ETV2_25802403_ChIP-Seq_MESCs_Mouse0.76563782
159CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.76412078
160MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.75742323
161MYCN_18555785_ChIP-Seq_MESCs_Mouse0.75733467

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.77511128
2MP0001529_abnormal_vocalization4.19211007
3MP0003880_abnormal_central_pattern3.87251730
4MP0001905_abnormal_dopamine_level3.49403398
5MP0006276_abnormal_autonomic_nervous3.06767113
6MP0003136_yellow_coat_color2.82475811
7MP0008877_abnormal_DNA_methylation2.70802034
8MP0001986_abnormal_taste_sensitivity2.60449593
9MP0001188_hyperpigmentation2.47999708
10MP0003646_muscle_fatigue2.45317668
11MP0006035_abnormal_mitochondrial_morpho2.33841010
12MP0002736_abnormal_nociception_after2.32563463
13MP0004142_abnormal_muscle_tone2.26560967
14MP0006036_abnormal_mitochondrial_physio2.16417996
15MP0001968_abnormal_touch/_nociception2.12333693
16MP0003186_abnormal_redox_activity2.10549219
17MP0004215_abnormal_myocardial_fiber2.01373978
18MP0003806_abnormal_nucleotide_metabolis1.99179144
19MP0000372_irregular_coat_pigmentation1.92502314
20MP0002638_abnormal_pupillary_reflex1.90647617
21MP0002735_abnormal_chemical_nociception1.90066236
22MP0003718_maternal_effect1.86377816
23MP0000569_abnormal_digit_pigmentation1.84487182
24MP0004043_abnormal_pH_regulation1.83138283
25MP0005171_absent_coat_pigmentation1.81884809
26MP0010386_abnormal_urinary_bladder1.81355687
27MP0002734_abnormal_mechanical_nocicepti1.78801709
28MP0009697_abnormal_copulation1.71049575
29MP0005645_abnormal_hypothalamus_physiol1.70070077
30MP0001440_abnormal_grooming_behavior1.68834774
31MP0009780_abnormal_chondrocyte_physiolo1.65660096
32MP0002272_abnormal_nervous_system1.61991695
33MP0003941_abnormal_skin_development1.60738049
34MP0005408_hypopigmentation1.60055190
35MP0009046_muscle_twitch1.58106298
36MP0001970_abnormal_pain_threshold1.55366428
37MP0002837_dystrophic_cardiac_calcinosis1.53710479
38MP0009745_abnormal_behavioral_response1.52914922
39MP0002064_seizures1.51226135
40MP0004147_increased_porphyrin_level1.50132733
41MP0002163_abnormal_gland_morphology1.48768884
42MP0005379_endocrine/exocrine_gland_phen1.46728920
43MP0002733_abnormal_thermal_nociception1.43459798
44MP0001984_abnormal_olfaction1.43072214
45MP0006072_abnormal_retinal_apoptosis1.42146850
46MP0002822_catalepsy1.41511873
47MP0005389_reproductive_system_phenotype1.40565059
48MP0004145_abnormal_muscle_electrophysio1.40298826
49MP0006292_abnormal_olfactory_placode1.37992524
50MP0004885_abnormal_endolymph1.37974278
51MP0002751_abnormal_autonomic_nervous1.37665196
52MP0005332_abnormal_amino_acid1.36078426
53MP0002132_abnormal_respiratory_system1.33533223
54MP0003567_abnormal_fetal_cardiomyocyte1.32697432
55MP0005386_behavior/neurological_phenoty1.31938268
56MP0004924_abnormal_behavior1.31938268
57MP0008932_abnormal_embryonic_tissue1.31221446
58MP0002572_abnormal_emotion/affect_behav1.30364344
59MP0003787_abnormal_imprinting1.30046883
60MP0002254_reproductive_system_inflammat1.29226748
61MP0008775_abnormal_heart_ventricle1.29006953
62MP0002876_abnormal_thyroid_physiology1.28710840
63MP0005423_abnormal_somatic_nervous1.28482351
64MP0004957_abnormal_blastocyst_morpholog1.26005197
65MP0008875_abnormal_xenobiotic_pharmacok1.24212166
66MP0005409_darkened_coat_color1.24029753
67MP0004381_abnormal_hair_follicle1.23812941
68MP0002067_abnormal_sensory_capabilities1.23435953
69MP0004130_abnormal_muscle_cell1.23114696
70MP0004270_analgesia1.20078145
71MP0002332_abnormal_exercise_endurance1.18666003
72MP0004133_heterotaxia1.17867588
73MP0001764_abnormal_homeostasis1.15242741
74MP0003011_delayed_dark_adaptation1.14190605
75MP0003693_abnormal_embryo_hatching1.13962144
76MP0003283_abnormal_digestive_organ1.11625035
77MP0005551_abnormal_eye_electrophysiolog1.10628881
78MP0001919_abnormal_reproductive_system1.08546785
79MP0003890_abnormal_embryonic-extraembry1.08144150
80MP0005084_abnormal_gallbladder_morpholo1.06766529
81MP0010329_abnormal_lipoprotein_level1.06002068
82MP0002938_white_spotting1.05809446
83MP0005253_abnormal_eye_physiology1.02687139
84MP0001501_abnormal_sleep_pattern1.01536039
85MP0003786_premature_aging1.00973314
86MP0003635_abnormal_synaptic_transmissio0.99345181
87MP0003122_maternal_imprinting0.99116711
88MP0000230_abnormal_systemic_arterial0.97686741
89MP0003137_abnormal_impulse_conducting0.97584662
90MP0005075_abnormal_melanosome_morpholog0.97574851
91MP0008057_abnormal_DNA_replication0.96669799
92MP0003195_calcinosis0.96628448
93MP0003315_abnormal_perineum_morphology0.95077176
94MP0002693_abnormal_pancreas_physiology0.95006618
95MP0003937_abnormal_limbs/digits/tail_de0.94531674
96MP0004134_abnormal_chest_morphology0.93536116
97MP0000778_abnormal_nervous_system0.93379896
98MP0000427_abnormal_hair_cycle0.92619854
99MP0008058_abnormal_DNA_repair0.92324861
100MP0008872_abnormal_physiological_respon0.91689603
101MP0001542_abnormal_bone_strength0.91678206
102MP0001486_abnormal_startle_reflex0.91376403
103MP0002277_abnormal_respiratory_mucosa0.91279750
104MP0004019_abnormal_vitamin_homeostasis0.91263347
105MP0008995_early_reproductive_senescence0.91114473
106MP0002184_abnormal_innervation0.90940313
107MP0001944_abnormal_pancreas_morphology0.90788749
108MP0004742_abnormal_vestibular_system0.90487068
109MP0005266_abnormal_metabolism0.89511868
110MP0005174_abnormal_tail_pigmentation0.88832575
111MP0001485_abnormal_pinna_reflex0.88381274
112MP0004084_abnormal_cardiac_muscle0.87438545
113MP0000631_abnormal_neuroendocrine_gland0.87044272
114MP0002557_abnormal_social/conspecific_i0.86749106
115MP0003724_increased_susceptibility_to0.86424980
116MP0000566_synostosis0.86372391
117MP0008004_abnormal_stomach_pH0.86253228
118MP0001963_abnormal_hearing_physiology0.85895736
119MP0005448_abnormal_energy_balance0.85002404
120MP0001727_abnormal_embryo_implantation0.84998849
121MP0002229_neurodegeneration0.83687130
122MP0005410_abnormal_fertilization0.82831376
123MP0002148_abnormal_hypersensitivity_rea0.82767524
124MP0002063_abnormal_learning/memory/cond0.82433139
125MP0004085_abnormal_heartbeat0.81961247
126MP0003950_abnormal_plasma_membrane0.81888362
127MP0005620_abnormal_muscle_contractility0.81784472
128MP0003121_genomic_imprinting0.81714715
129MP0005646_abnormal_pituitary_gland0.81504222
130MP0008789_abnormal_olfactory_epithelium0.81272476
131MP0002102_abnormal_ear_morphology0.80761622
132MP0000538_abnormal_urinary_bladder0.79251325
133MP0001502_abnormal_circadian_rhythm0.78515553
134MP0000026_abnormal_inner_ear0.78482212
135MP0002160_abnormal_reproductive_system0.78221883
136MP0005636_abnormal_mineral_homeostasis0.78011390
137MP0005376_homeostasis/metabolism_phenot0.76217600
138MP0002752_abnormal_somatic_nervous0.76214869
139MP0001664_abnormal_digestion0.76114472
140MP0008260_abnormal_autophagy0.75791567
141MP0004036_abnormal_muscle_relaxation0.73937563
142MP0002928_abnormal_bile_duct0.73612862
143MP0000749_muscle_degeneration0.71899355

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.88080971
2Abnormal mitochondria in muscle tissue (HP:0008316)6.22265200
3Mitochondrial inheritance (HP:0001427)6.06652794
4Progressive macrocephaly (HP:0004481)5.83540462
5Acute encephalopathy (HP:0006846)5.55897403
6Increased CSF lactate (HP:0002490)5.17236668
7Increased hepatocellular lipid droplets (HP:0006565)5.09070891
8Hepatocellular necrosis (HP:0001404)4.87763566
9Lipid accumulation in hepatocytes (HP:0006561)4.47215116
10Renal Fanconi syndrome (HP:0001994)4.43787452
11Hepatic necrosis (HP:0002605)4.36900876
12Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.30394949
13Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.94801711
143-Methylglutaconic aciduria (HP:0003535)3.91387538
15Cerebral edema (HP:0002181)3.81802079
16Increased intramyocellular lipid droplets (HP:0012240)3.77586754
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.71721455
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.71721455
19Abnormality of cells of the erythroid lineage (HP:0012130)3.70174978
20Exercise intolerance (HP:0003546)3.58487147
21Optic disc pallor (HP:0000543)3.55521388
22Respiratory failure (HP:0002878)3.48997453
23Lactic acidosis (HP:0003128)3.45271277
24Exertional dyspnea (HP:0002875)3.43735464
25Abnormality of glycolysis (HP:0004366)3.43018229
26Increased serum pyruvate (HP:0003542)3.43018229
27Congenital stationary night blindness (HP:0007642)3.42948782
28Leukodystrophy (HP:0002415)3.42247610
29Increased serum lactate (HP:0002151)3.38775630
30Abnormality of the renal cortex (HP:0011035)3.32120930
31Abnormal number of erythroid precursors (HP:0012131)3.28540850
32Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.20685143
33Abnormality of renal resorption (HP:0011038)3.13091176
34Renal cortical cysts (HP:0000803)3.12789956
35Increased muscle lipid content (HP:0009058)3.04548277
36Nephronophthisis (HP:0000090)2.91410823
37Respiratory difficulties (HP:0002880)2.90550906
38Abolished electroretinogram (ERG) (HP:0000550)2.81831789
39Abnormality of midbrain morphology (HP:0002418)2.80316256
40Molar tooth sign on MRI (HP:0002419)2.80316256
41Congenital, generalized hypertrichosis (HP:0004540)2.79690967
42Gaze-evoked nystagmus (HP:0000640)2.79047434
43Macrocytic anemia (HP:0001972)2.77315781
44Type II lissencephaly (HP:0007260)2.73304627
45Hypothermia (HP:0002045)2.69657314
46Parakeratosis (HP:0001036)2.63393641
47Genetic anticipation (HP:0003743)2.63370601
48Large for gestational age (HP:0001520)2.60049526
49Abnormality of the renal medulla (HP:0100957)2.58043555
50Pendular nystagmus (HP:0012043)2.54614222
51Abnormality of urine glucose concentration (HP:0011016)2.51014232
52Glycosuria (HP:0003076)2.51014232
53Reticulocytopenia (HP:0001896)2.50307907
54Medial flaring of the eyebrow (HP:0010747)2.49238424
55Type I transferrin isoform profile (HP:0003642)2.47920844
56Furrowed tongue (HP:0000221)2.38663164
57Neuroendocrine neoplasm (HP:0100634)2.38245930
58Hyperglycinuria (HP:0003108)2.36552788
59Progressive cerebellar ataxia (HP:0002073)2.34852838
60Broad-based gait (HP:0002136)2.32041059
61Hypoplasia of the pons (HP:0012110)2.31349959
62Abnormality of secondary sexual hair (HP:0009888)2.31213753
63Abnormality of the axillary hair (HP:0100134)2.31213753
64Ketoacidosis (HP:0001993)2.30204429
65Congenital ichthyosiform erythroderma (HP:0007431)2.29917951
66CNS demyelination (HP:0007305)2.29279435
67Abnormality of the pons (HP:0007361)2.28431444
68Pheochromocytoma (HP:0002666)2.28188642
69Hyperphosphaturia (HP:0003109)2.27843179
70Cerebral hypomyelination (HP:0006808)2.27719219
71Inability to walk (HP:0002540)2.26101810
72X-linked dominant inheritance (HP:0001423)2.24773665
73Pallor (HP:0000980)2.22000616
74Abnormal pupillary function (HP:0007686)2.18402990
75Abnormal ciliary motility (HP:0012262)2.15279942
76Hyperventilation (HP:0002883)2.15233643
77Gait imbalance (HP:0002141)2.14465287
78Aplasia/Hypoplasia of the sacrum (HP:0008517)2.13520177
79Congenital primary aphakia (HP:0007707)2.12959371
80Abnormal respiratory epithelium morphology (HP:0012253)2.12319701
81Abnormal respiratory motile cilium morphology (HP:0005938)2.12319701
82Pancreatic fibrosis (HP:0100732)2.11626698
83Abnormal drinking behavior (HP:0030082)2.11546819
84Polydipsia (HP:0001959)2.11546819
85Clumsiness (HP:0002312)2.11291323
86Limb dystonia (HP:0002451)2.11062486
87Confusion (HP:0001289)2.10821587
88Lethargy (HP:0001254)2.08970099
89Decreased circulating renin level (HP:0003351)2.08807417
90Emotional lability (HP:0000712)2.08597421
91Hypoglycemic coma (HP:0001325)2.08152822
92Hyperglycinemia (HP:0002154)2.07013881
93Methylmalonic aciduria (HP:0012120)2.05623824
94Abnormal hair whorl (HP:0010721)2.05473794
95Tubular atrophy (HP:0000092)2.05360076
96Attenuation of retinal blood vessels (HP:0007843)2.03391148
97Febrile seizures (HP:0002373)2.02260586
98Palpitations (HP:0001962)2.00353187
99Keratoconus (HP:0000563)2.00301119
100Increased corneal curvature (HP:0100692)2.00301119
101Cystic liver disease (HP:0006706)1.98907339
102Muscle hypertrophy of the lower extremities (HP:0008968)1.98056731
103Nephrogenic diabetes insipidus (HP:0009806)1.97913069
104Conjunctival hamartoma (HP:0100780)1.97355526
105Calf muscle hypertrophy (HP:0008981)1.96989309
106Hyperinsulinemic hypoglycemia (HP:0000825)1.96663149
107Aplasia/hypoplasia of the uterus (HP:0008684)1.95454281
108Progressive inability to walk (HP:0002505)1.94346833
109Abnormal rod and cone electroretinograms (HP:0008323)1.93210309
110CNS hypomyelination (HP:0003429)1.92940283
111True hermaphroditism (HP:0010459)1.90760365
112Chronic hepatic failure (HP:0100626)1.90303334
113Renal tubular dysfunction (HP:0000124)1.89527645
114Ketosis (HP:0001946)1.87957857
115Sclerocornea (HP:0000647)1.86791962
116Abnormality of glycine metabolism (HP:0010895)1.85956365
117Abnormality of serine family amino acid metabolism (HP:0010894)1.85956365
118Abnormality of vitamin B metabolism (HP:0004340)1.85176450
119Hemiparesis (HP:0001269)1.84814970
120Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84650224
121Male pseudohermaphroditism (HP:0000037)1.84272053
122Microvesicular hepatic steatosis (HP:0001414)1.82454323
123Methylmalonic acidemia (HP:0002912)1.82291242
124Dynein arm defect of respiratory motile cilia (HP:0012255)1.81962051
125Absent/shortened dynein arms (HP:0200106)1.81962051
126Optic nerve hypoplasia (HP:0000609)1.81595228
127Vaginal atresia (HP:0000148)1.81247565
128Cerebellar dysplasia (HP:0007033)1.80664120
129Abnormal urine phosphate concentration (HP:0012599)1.79952846
130Dialeptic seizures (HP:0011146)1.79086896
131Genital tract atresia (HP:0001827)1.78920425
132Fair hair (HP:0002286)1.77939889
133Abnormality of serum amino acid levels (HP:0003112)1.77857124
134Absence seizures (HP:0002121)1.76391511
135Metabolic alkalosis (HP:0200114)1.75947931
136Birth length less than 3rd percentile (HP:0003561)1.75337656
137Abnormal respiratory motile cilium physiology (HP:0012261)1.75187937
138Aplasia/Hypoplasia of the tibia (HP:0005772)1.74860595
139Concave nail (HP:0001598)1.74618440
140Homocystinuria (HP:0002156)1.74427998
141Abnormality of homocysteine metabolism (HP:0010919)1.74427998
142Abnormality of placental membranes (HP:0011409)1.74405989
143Amniotic constriction ring (HP:0009775)1.74405989
144Stenosis of the external auditory canal (HP:0000402)1.73246504
145Poor suck (HP:0002033)1.72051987
146Blindness (HP:0000618)1.71581482
147Absent thumb (HP:0009777)1.70969958
148Bilateral microphthalmos (HP:0007633)1.70918607
149Protruding tongue (HP:0010808)1.70300137
150Abnormal protein glycosylation (HP:0012346)1.68149275
151Abnormal glycosylation (HP:0012345)1.68149275
152Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.68149275
153Abnormal protein N-linked glycosylation (HP:0012347)1.68149275
154Abnormal hemoglobin (HP:0011902)1.67762745
155Myokymia (HP:0002411)1.67644859
156Pancreatic cysts (HP:0001737)1.64327551
157Median cleft lip (HP:0000161)1.61499623
158Hypoplasia of the uterus (HP:0000013)1.60167990
159Abnormality of alanine metabolism (HP:0010916)1.58185147
160Hyperalaninemia (HP:0003348)1.58185147
161Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.58185147
162Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.57062403
163Delusions (HP:0000746)1.53827056
164Progressive external ophthalmoplegia (HP:0000590)1.53040565
165Breast hypoplasia (HP:0003187)1.52797968
166Patchy hypopigmentation of hair (HP:0011365)1.51326532
167Poor coordination (HP:0002370)1.50593903

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.22436028
2CASK3.33595776
3MAP3K123.22692527
4MST43.00557308
5NME22.96554458
6STK162.92367553
7NME12.61298104
8PNCK2.54186114
9VRK12.49520948
10PBK2.39561777
11BUB12.30855139
12INSRR2.15855485
13MAPKAPK32.09631005
14ACVR1B1.99491396
15GRK51.98497573
16ARAF1.94851805
17EIF2AK11.88921346
18WEE11.86406674
19TAOK31.85033215
20BCR1.71840546
21SRPK11.68512415
22CDK191.63073522
23DAPK21.62687754
24MYLK1.61766962
25TLK11.61364065
26MAP4K21.57572786
27GRK71.57183886
28BMPR1B1.56842706
29STK391.54804427
30OXSR11.50257948
31ADRBK21.48111368
32MUSK1.42370605
33EIF2AK31.40089801
34MAPKAPK51.39086027
35TNIK1.34829036
36LIMK11.33513622
37PIM21.33085354
38BMPR21.32255359
39TSSK61.28226679
40NLK1.22372097
41VRK21.22263654
42FGFR21.21625209
43TAF11.20667555
44AKT31.19934034
45TGFBR11.14583312
46DYRK21.09953842
47IRAK41.09874236
48CDC71.09513161
49STK38L1.08029685
50PAK31.07942198
51MAPK151.06584351
52PLK21.06397456
53BRAF1.06111810
54BRSK21.02992384
55STK31.00976820
56MAP2K70.98760993
57PLK40.98304893
58ZAK0.98255347
59ABL20.94001308
60IRAK10.92652137
61IRAK20.91599037
62IRAK30.89611665
63PLK30.89101328
64CSNK1G30.88959895
65FLT30.87747707
66TRPM70.86245866
67AURKA0.83879664
68SIK30.83395676
69YES10.83085661
70WNK40.78951489
71PASK0.77817710
72OBSCN0.76350772
73CCNB10.76249559
74CAMK2B0.74792667
75MKNK10.73428314
76EIF2AK20.72903135
77NTRK30.72902001
78NEK60.72029186
79MAPK130.70901013
80TXK0.70386427
81TESK20.69806356
82GRK10.66215745
83WNK10.65928661
84ADRBK10.63906357
85TTK0.63481887
86CSNK2A10.63402187
87CAMK2D0.63099935
88CAMK2A0.62989052
89CSNK1A10.61889675
90CHEK20.61659694
91MAP3K40.61431187
92PIK3CA0.61361009
93NEK10.61068310
94CSNK2A20.59175409
95PRKCE0.57732511
96ROCK20.56503757
97CSNK1E0.55021038
98MAP2K60.54872250
99WNK30.54526612
100MARK10.54306436
101CAMK2G0.52865333
102CDK80.52385363
103RPS6KB20.51969969
104RPS6KA50.51480309
105UHMK10.49916846
106PRKCG0.47965897
107MKNK20.47954374
108TESK10.46915621
109DAPK10.46615983
110TIE10.46192815
111CAMKK20.45654737
112EPHA20.45318353
113EPHA30.45171388
114PLK10.45067843
115CSNK1G10.44942664
116PRKACA0.44286628
117TEC0.43800964
118MINK10.42423826
119CSNK1A1L0.42182414
120LATS10.41372392
121ERBB30.41206907
122PRKAA10.41130617
123PIK3CG0.40464869
124PRKAA20.40339980
125PDK20.38706003
126NEK20.37896567
127CDK140.37346465
128FGR0.37038706
129PRKCI0.36124998
130CSNK1D0.35410414
131NUAK10.35306996
132ALK0.35295196
133PRKCA0.34728948
134ILK0.34554385
135PRKG10.34453513
136PINK10.33507444
137CAMK10.33283008
138BCKDK0.32998590
139CSNK1G20.32668536
140PHKG10.32598697
141PHKG20.32598697
142EPHA40.32256639
143TNK20.31673369
144CDK180.31201639

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.89717761
2Parkinsons disease_Homo sapiens_hsa050124.97666695
3Ribosome_Homo sapiens_hsa030104.60460475
4Proteasome_Homo sapiens_hsa030504.16636360
5Alzheimers disease_Homo sapiens_hsa050103.65751619
6Huntingtons disease_Homo sapiens_hsa050163.59845833
7RNA polymerase_Homo sapiens_hsa030203.19424287
8Protein export_Homo sapiens_hsa030603.19230528
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.99952760
10Selenocompound metabolism_Homo sapiens_hsa004502.38315080
11One carbon pool by folate_Homo sapiens_hsa006702.11355477
12Cardiac muscle contraction_Homo sapiens_hsa042602.04091909
13Collecting duct acid secretion_Homo sapiens_hsa049661.97255470
14Pyrimidine metabolism_Homo sapiens_hsa002401.75683309
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.74096896
16Fatty acid elongation_Homo sapiens_hsa000621.73018147
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71849724
18Tryptophan metabolism_Homo sapiens_hsa003801.67556546
19Nitrogen metabolism_Homo sapiens_hsa009101.67456603
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53130877
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49921494
22Vibrio cholerae infection_Homo sapiens_hsa051101.39572085
23Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.37435795
24Vitamin digestion and absorption_Homo sapiens_hsa049771.35113196
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.33456945
26Insulin secretion_Homo sapiens_hsa049111.29781116
27Homologous recombination_Homo sapiens_hsa034401.28156696
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.25895781
29Nucleotide excision repair_Homo sapiens_hsa034201.25793350
30Sulfur metabolism_Homo sapiens_hsa009201.23224794
31Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.22776678
32Mismatch repair_Homo sapiens_hsa034301.21816570
33Spliceosome_Homo sapiens_hsa030401.20701847
34Caffeine metabolism_Homo sapiens_hsa002321.19784629
35Basal transcription factors_Homo sapiens_hsa030221.18129528
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.16074814
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.09443687
38Purine metabolism_Homo sapiens_hsa002301.08680052
39Olfactory transduction_Homo sapiens_hsa047401.07187068
40SNARE interactions in vesicular transport_Homo sapiens_hsa041301.05033576
41DNA replication_Homo sapiens_hsa030301.03133417
42Glutathione metabolism_Homo sapiens_hsa004801.00992859
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.96294995
44Rheumatoid arthritis_Homo sapiens_hsa053230.93476154
45Morphine addiction_Homo sapiens_hsa050320.92763547
46Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92259277
47Arachidonic acid metabolism_Homo sapiens_hsa005900.91870235
48Pyruvate metabolism_Homo sapiens_hsa006200.91672660
49Metabolic pathways_Homo sapiens_hsa011000.91403922
50Steroid biosynthesis_Homo sapiens_hsa001000.91021751
51Circadian rhythm_Homo sapiens_hsa047100.90653736
52Synaptic vesicle cycle_Homo sapiens_hsa047210.89494622
53Nicotine addiction_Homo sapiens_hsa050330.84514477
54Pentose and glucuronate interconversions_Homo sapiens_hsa000400.84174282
55Phototransduction_Homo sapiens_hsa047440.84048995
56Folate biosynthesis_Homo sapiens_hsa007900.80202733
57Tyrosine metabolism_Homo sapiens_hsa003500.79879522
58Circadian entrainment_Homo sapiens_hsa047130.79245306
59Glutamatergic synapse_Homo sapiens_hsa047240.78563620
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.76575485
61RNA degradation_Homo sapiens_hsa030180.75586524
62Regulation of autophagy_Homo sapiens_hsa041400.75551270
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72376880
64Mineral absorption_Homo sapiens_hsa049780.72083210
65Ether lipid metabolism_Homo sapiens_hsa005650.71692541
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70660834
67Fatty acid degradation_Homo sapiens_hsa000710.69437574
68Calcium signaling pathway_Homo sapiens_hsa040200.67138988
69Serotonergic synapse_Homo sapiens_hsa047260.66186098
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65824663
71Fat digestion and absorption_Homo sapiens_hsa049750.63720721
72Fanconi anemia pathway_Homo sapiens_hsa034600.63662568
73Sulfur relay system_Homo sapiens_hsa041220.62600758
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62225504
75RNA transport_Homo sapiens_hsa030130.62201357
76Primary bile acid biosynthesis_Homo sapiens_hsa001200.61212928
77Non-homologous end-joining_Homo sapiens_hsa034500.59814952
78Phenylalanine metabolism_Homo sapiens_hsa003600.59617475
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59390653
80Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56850378
81Phagosome_Homo sapiens_hsa041450.55557390
82Linoleic acid metabolism_Homo sapiens_hsa005910.54978442
83Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.53500410
84Propanoate metabolism_Homo sapiens_hsa006400.52791115
85Sphingolipid metabolism_Homo sapiens_hsa006000.52732524
86Fatty acid metabolism_Homo sapiens_hsa012120.52549144
87Histidine metabolism_Homo sapiens_hsa003400.52496144
88Renin secretion_Homo sapiens_hsa049240.51674184
89Chemical carcinogenesis_Homo sapiens_hsa052040.50127159
90Peroxisome_Homo sapiens_hsa041460.47538060
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.47298316
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46818795
93Dopaminergic synapse_Homo sapiens_hsa047280.46699350
94Salivary secretion_Homo sapiens_hsa049700.46681539
95Base excision repair_Homo sapiens_hsa034100.46251996
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42986078
97beta-Alanine metabolism_Homo sapiens_hsa004100.42479081
98Carbon metabolism_Homo sapiens_hsa012000.42103418
99Epstein-Barr virus infection_Homo sapiens_hsa051690.40347059
100Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.40097828
101Butanoate metabolism_Homo sapiens_hsa006500.39829213
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39502694
103Taste transduction_Homo sapiens_hsa047420.39235208
104Fructose and mannose metabolism_Homo sapiens_hsa000510.39223118
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.39148962
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38478035
107ABC transporters_Homo sapiens_hsa020100.37921926
108Cysteine and methionine metabolism_Homo sapiens_hsa002700.37589925
109Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.37431752
110Glycerolipid metabolism_Homo sapiens_hsa005610.37103598
111Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.36771708
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35846746
113Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.33877428
114Arginine and proline metabolism_Homo sapiens_hsa003300.31005187
115alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30147837
116Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.29236389
117GABAergic synapse_Homo sapiens_hsa047270.26405647
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.25990386
119Other glycan degradation_Homo sapiens_hsa005110.25599057
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.23749914
121Drug metabolism - other enzymes_Homo sapiens_hsa009830.23609898
122Autoimmune thyroid disease_Homo sapiens_hsa053200.22847340
123Retinol metabolism_Homo sapiens_hsa008300.21485742
124Asthma_Homo sapiens_hsa053100.20092364
125Allograft rejection_Homo sapiens_hsa053300.19195772
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.18840270
127Alcoholism_Homo sapiens_hsa050340.18729957
128Graft-versus-host disease_Homo sapiens_hsa053320.18249454
129Cocaine addiction_Homo sapiens_hsa050300.16448938
130Amphetamine addiction_Homo sapiens_hsa050310.15910579
131Pentose phosphate pathway_Homo sapiens_hsa000300.13916990
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.13752184
133Vitamin B6 metabolism_Homo sapiens_hsa007500.13112076
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.12208294
135Type I diabetes mellitus_Homo sapiens_hsa049400.11760359

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