Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.12758587 |
2 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 6.07739659 |
3 | locomotory exploration behavior (GO:0035641) | 5.81177580 |
4 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.79066059 |
5 | vocalization behavior (GO:0071625) | 5.68367858 |
6 | synaptic vesicle maturation (GO:0016188) | 5.67066709 |
7 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 5.61838642 |
8 | synaptic vesicle exocytosis (GO:0016079) | 5.57873961 |
9 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.48051530 |
10 | glutamate secretion (GO:0014047) | 5.32782078 |
11 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.29464043 |
12 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.26519522 |
13 | protein localization to synapse (GO:0035418) | 5.18952467 |
14 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.01917754 |
15 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.97963983 |
16 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.94311630 |
17 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.87757282 |
18 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.75396431 |
19 | exploration behavior (GO:0035640) | 4.68914834 |
20 | neuronal action potential propagation (GO:0019227) | 4.64593986 |
21 | neuron cell-cell adhesion (GO:0007158) | 4.63118266 |
22 | dendritic spine morphogenesis (GO:0060997) | 4.50536593 |
23 | regulation of synaptic vesicle transport (GO:1902803) | 4.49815209 |
24 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.47062541 |
25 | synaptic transmission, glutamatergic (GO:0035249) | 4.46760382 |
26 | regulation of synapse structural plasticity (GO:0051823) | 4.45356464 |
27 | neurofilament cytoskeleton organization (GO:0060052) | 4.45264238 |
28 | glutamate receptor signaling pathway (GO:0007215) | 4.41426162 |
29 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.39736136 |
30 | regulation of dendritic spine morphogenesis (GO:0061001) | 4.26163133 |
31 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.24842850 |
32 | layer formation in cerebral cortex (GO:0021819) | 4.23178481 |
33 | neuron-neuron synaptic transmission (GO:0007270) | 4.21505948 |
34 | nucleobase catabolic process (GO:0046113) | 4.20251420 |
35 | establishment of mitochondrion localization (GO:0051654) | 4.19392423 |
36 | neurotransmitter secretion (GO:0007269) | 4.18502957 |
37 | positive regulation of membrane potential (GO:0045838) | 4.12351421 |
38 | regulation of postsynaptic membrane potential (GO:0060078) | 4.02327326 |
39 | positive regulation of neurotransmitter secretion (GO:0001956) | 4.01612631 |
40 | long-term memory (GO:0007616) | 3.99999374 |
41 | regulation of synaptic plasticity (GO:0048167) | 3.96331551 |
42 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.87874270 |
43 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.86784666 |
44 | mitochondrion transport along microtubule (GO:0047497) | 3.86784666 |
45 | neuron recognition (GO:0008038) | 3.86019672 |
46 | positive regulation of synapse maturation (GO:0090129) | 3.85867768 |
47 | cell migration in hindbrain (GO:0021535) | 3.79102249 |
48 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.75879553 |
49 | long-term synaptic potentiation (GO:0060291) | 3.74739838 |
50 | positive regulation of neurotransmitter transport (GO:0051590) | 3.66028162 |
51 | postsynaptic membrane organization (GO:0001941) | 3.63019017 |
52 | regulation of dendritic spine development (GO:0060998) | 3.61891372 |
53 | axonal fasciculation (GO:0007413) | 3.61803492 |
54 | dendritic spine organization (GO:0097061) | 3.61371918 |
55 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.56508809 |
56 | auditory behavior (GO:0031223) | 3.55177855 |
57 | proline transport (GO:0015824) | 3.53385317 |
58 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.53319023 |
59 | presynaptic membrane assembly (GO:0097105) | 3.52835522 |
60 | synaptic vesicle endocytosis (GO:0048488) | 3.52465320 |
61 | regulation of neurotransmitter secretion (GO:0046928) | 3.48353740 |
62 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.47881991 |
63 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.46086044 |
64 | neuromuscular process controlling balance (GO:0050885) | 3.42346271 |
65 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.40048047 |
66 | transmission of nerve impulse (GO:0019226) | 3.38386750 |
67 | gamma-aminobutyric acid transport (GO:0015812) | 3.36518097 |
68 | positive regulation of dendritic spine development (GO:0060999) | 3.36459021 |
69 | response to histamine (GO:0034776) | 3.35143333 |
70 | regulation of vesicle fusion (GO:0031338) | 3.34969063 |
71 | behavioral fear response (GO:0001662) | 3.34904986 |
72 | behavioral defense response (GO:0002209) | 3.34904986 |
73 | neurotransmitter transport (GO:0006836) | 3.34175150 |
74 | cellular potassium ion homeostasis (GO:0030007) | 3.34076392 |
75 | presynaptic membrane organization (GO:0097090) | 3.29915054 |
76 | activation of protein kinase A activity (GO:0034199) | 3.29428514 |
77 | membrane depolarization (GO:0051899) | 3.29009123 |
78 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.26537418 |
79 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.25629543 |
80 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.24322026 |
81 | learning (GO:0007612) | 3.22926096 |
82 | regulation of glutamate secretion (GO:0014048) | 3.22280380 |
83 | response to auditory stimulus (GO:0010996) | 3.22269254 |
84 | behavioral response to nicotine (GO:0035095) | 3.22067509 |
85 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.21753902 |
86 | fear response (GO:0042596) | 3.19923632 |
87 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.19662612 |
88 | regulation of female receptivity (GO:0045924) | 3.18634873 |
89 | behavioral response to cocaine (GO:0048148) | 3.18573470 |
90 | regulation of neurotransmitter transport (GO:0051588) | 3.18160445 |
91 | innervation (GO:0060384) | 3.15081359 |
92 | positive regulation of synaptic transmission (GO:0050806) | 3.12279646 |
93 | regulation of neurotransmitter levels (GO:0001505) | 3.11706025 |
94 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.10948262 |
95 | positive regulation by symbiont of host defense response (GO:0052509) | 3.08963782 |
96 | modulation by symbiont of host defense response (GO:0052031) | 3.08963782 |
97 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.08963782 |
98 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.08963782 |
99 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.08963782 |
100 | modulation by symbiont of host immune response (GO:0052553) | 3.08963782 |
101 | regulation of synaptic transmission (GO:0050804) | 3.08123934 |
102 | negative regulation of cell killing (GO:0031342) | 3.05654144 |
103 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.05654144 |
104 | cerebellar granule cell differentiation (GO:0021707) | 3.04606770 |
105 | membrane hyperpolarization (GO:0060081) | 3.04571021 |
106 | detection of calcium ion (GO:0005513) | 3.04089902 |
107 | dendrite morphogenesis (GO:0048813) | 3.03766128 |
108 | long term synaptic depression (GO:0060292) | 3.03287566 |
109 | chemosensory behavior (GO:0007635) | 3.01595517 |
110 | mechanosensory behavior (GO:0007638) | 2.99534742 |
111 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.99371509 |
112 | prepulse inhibition (GO:0060134) | 2.97813399 |
113 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.97541467 |
114 | negative regulation of microtubule polymerization (GO:0031115) | 2.97108141 |
115 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.96953538 |
116 | regulation of synapse maturation (GO:0090128) | 2.96382922 |
117 | neuronal ion channel clustering (GO:0045161) | 2.96164017 |
118 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.96153546 |
119 | vesicle transport along microtubule (GO:0047496) | 2.95323646 |
120 | membrane depolarization during action potential (GO:0086010) | 2.95265063 |
121 | synaptic transmission (GO:0007268) | 2.94153640 |
122 | positive regulation of synapse assembly (GO:0051965) | 2.93625962 |
123 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.93490759 |
124 | macrophage activation involved in immune response (GO:0002281) | 2.87580251 |
125 | regulation of ARF protein signal transduction (GO:0032012) | 2.81324129 |
126 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 2.79005627 |
127 | adult walking behavior (GO:0007628) | 2.78444122 |
128 | cell-cell junction maintenance (GO:0045217) | 2.77446538 |
129 | axon extension (GO:0048675) | 2.76373163 |
130 | synapse assembly (GO:0007416) | 2.76086922 |
131 | negative regulation of axonogenesis (GO:0050771) | 2.74624087 |
132 | regulation of respiratory system process (GO:0044065) | 2.72824881 |
133 | neuromuscular synaptic transmission (GO:0007274) | 2.72744577 |
134 | response to parathyroid hormone (GO:0071107) | 2.67743309 |
135 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 2.67459925 |
136 | L-amino acid import (GO:0043092) | 2.66505314 |
137 | startle response (GO:0001964) | 2.65070403 |
138 | regulation of collateral sprouting (GO:0048670) | 2.62630744 |
139 | neuromuscular process controlling posture (GO:0050884) | 2.59706053 |
140 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.58065275 |
141 | activated T cell proliferation (GO:0050798) | 2.58040132 |
142 | regulation of regulated secretory pathway (GO:1903305) | 2.55333079 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.17326939 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.72619979 |
3 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.21185737 |
4 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.19880075 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.09629033 |
6 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.90309162 |
7 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.82709641 |
8 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.75660492 |
9 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.75660492 |
10 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.70899655 |
11 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.70721452 |
12 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.59745762 |
13 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.57235392 |
14 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.56150481 |
15 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.55038724 |
16 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.54840742 |
17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.51774915 |
18 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.35537899 |
19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.31917244 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.30972319 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.28235643 |
22 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.26067647 |
23 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.13402707 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.11824885 |
25 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.02594504 |
26 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.02347489 |
27 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.95242313 |
28 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.90202654 |
29 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.89430797 |
30 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.83941500 |
31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.81599596 |
32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.76799464 |
33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.71887202 |
34 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.65658682 |
35 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.64660482 |
36 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.61731494 |
37 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.60412095 |
38 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.46035775 |
39 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.45650236 |
40 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.43502706 |
41 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.39673247 |
42 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.39368620 |
43 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.36543854 |
44 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.36099363 |
45 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.35744674 |
46 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.35664055 |
47 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.34709255 |
48 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.34526107 |
49 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.34372068 |
50 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33480652 |
51 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.32257815 |
52 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.29396569 |
53 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.29389289 |
54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28250537 |
55 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.27925872 |
56 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.27758952 |
57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.27641493 |
58 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.25012064 |
59 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.24660057 |
60 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.23572618 |
61 | AR_25329375_ChIP-Seq_VCAP_Human | 1.21967572 |
62 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.18959538 |
63 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18634904 |
64 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.17954539 |
65 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17673274 |
66 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.17465775 |
67 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.17363312 |
68 | AR_19668381_ChIP-Seq_PC3_Human | 1.17180872 |
69 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.16626442 |
70 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.15232087 |
71 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.14942951 |
72 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.13989238 |
73 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13146079 |
74 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.13120405 |
75 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12270508 |
76 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.11815568 |
77 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.11029484 |
78 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.10639971 |
79 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.09542187 |
80 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.09460652 |
81 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.08794169 |
82 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.08654456 |
83 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.06875939 |
84 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.06440930 |
85 | TCF4_23295773_ChIP-Seq_U87_Human | 1.05853590 |
86 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.05321635 |
87 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.05215366 |
88 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04404678 |
89 | KDM2B_26808549_Chip-Seq_K562_Human | 1.03651205 |
90 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.03616035 |
91 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.01871665 |
92 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.01509172 |
93 | FUS_26573619_Chip-Seq_HEK293_Human | 1.01504938 |
94 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.00406874 |
95 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.00197866 |
96 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98616739 |
97 | VDR_22108803_ChIP-Seq_LS180_Human | 0.97329804 |
98 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.97272225 |
99 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.96605449 |
100 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.96146276 |
101 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.95924891 |
102 | TP53_16413492_ChIP-PET_HCT116_Human | 0.95476979 |
103 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.95270957 |
104 | RXR_22108803_ChIP-Seq_LS180_Human | 0.95185747 |
105 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.94919137 |
106 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.94337412 |
107 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.93578206 |
108 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.93214578 |
109 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.92979488 |
110 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.92522339 |
111 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.91821531 |
112 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.91398934 |
113 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.90930614 |
114 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.89830907 |
115 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.89534669 |
116 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89534669 |
117 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.88786238 |
118 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.88553352 |
119 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88552616 |
120 | * DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.88226026 |
121 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.87959380 |
122 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87944303 |
123 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.87702476 |
124 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.87320724 |
125 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.85282384 |
126 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.84914518 |
127 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 0.84873439 |
128 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.82999934 |
129 | SPI1_23127762_ChIP-Seq_K562_Human | 0.82503269 |
130 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.81423105 |
131 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.80126220 |
132 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79703213 |
133 | P68_20966046_ChIP-Seq_HELA_Human | 0.79094241 |
134 | * VDR_24763502_ChIP-Seq_THP-1_Human | 0.79001694 |
135 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.78212496 |
136 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.77357326 |
137 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.76840239 |
138 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.72957372 |
139 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.72948812 |
140 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.72719022 |
141 | MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse | 0.71881869 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 7.16332733 |
2 | MP0003880_abnormal_central_pattern | 5.45594090 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.37331449 |
4 | MP0004270_analgesia | 4.00745092 |
5 | MP0002063_abnormal_learning/memory/cond | 3.62131272 |
6 | MP0009745_abnormal_behavioral_response | 3.57085287 |
7 | MP0002822_catalepsy | 3.21287121 |
8 | MP0002064_seizures | 3.19367422 |
9 | MP0001968_abnormal_touch/_nociception | 3.03015494 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.95359751 |
11 | MP0009046_muscle_twitch | 2.69506916 |
12 | MP0001486_abnormal_startle_reflex | 2.63536973 |
13 | MP0002272_abnormal_nervous_system | 2.57733601 |
14 | MP0002734_abnormal_mechanical_nocicepti | 2.56841906 |
15 | MP0005423_abnormal_somatic_nervous | 2.52323316 |
16 | MP0009780_abnormal_chondrocyte_physiolo | 2.49844346 |
17 | MP0002736_abnormal_nociception_after | 2.36697316 |
18 | MP0001501_abnormal_sleep_pattern | 2.26576734 |
19 | MP0001440_abnormal_grooming_behavior | 2.16260816 |
20 | MP0003123_paternal_imprinting | 2.13621616 |
21 | MP0003121_genomic_imprinting | 2.10430998 |
22 | MP0002735_abnormal_chemical_nociception | 1.94683299 |
23 | MP0002733_abnormal_thermal_nociception | 1.89761972 |
24 | MP0003329_amyloid_beta_deposits | 1.86730399 |
25 | MP0001970_abnormal_pain_threshold | 1.86387622 |
26 | MP0000778_abnormal_nervous_system | 1.86242195 |
27 | MP0002067_abnormal_sensory_capabilities | 1.84488722 |
28 | MP0002909_abnormal_adrenal_gland | 1.79057284 |
29 | MP0004811_abnormal_neuron_physiology | 1.78854559 |
30 | MP0003879_abnormal_hair_cell | 1.78820974 |
31 | MP0008569_lethality_at_weaning | 1.78436015 |
32 | MP0002557_abnormal_social/conspecific_i | 1.74713491 |
33 | MP0004924_abnormal_behavior | 1.69037814 |
34 | MP0005386_behavior/neurological_phenoty | 1.69037814 |
35 | MP0002184_abnormal_innervation | 1.67065824 |
36 | MP0005646_abnormal_pituitary_gland | 1.65764843 |
37 | MP0004858_abnormal_nervous_system | 1.61610173 |
38 | MP0001529_abnormal_vocalization | 1.61501574 |
39 | MP0000955_abnormal_spinal_cord | 1.49804681 |
40 | MP0003303_peritoneal_inflammation | 1.49725407 |
41 | MP0002653_abnormal_ependyma_morphology | 1.47244035 |
42 | MP0001984_abnormal_olfaction | 1.43879543 |
43 | MP0002066_abnormal_motor_capabilities/c | 1.39237672 |
44 | MP0003787_abnormal_imprinting | 1.38803215 |
45 | MP0002882_abnormal_neuron_morphology | 1.37282606 |
46 | MP0008877_abnormal_DNA_methylation | 1.36672544 |
47 | MP0004885_abnormal_endolymph | 1.33290230 |
48 | MP0003633_abnormal_nervous_system | 1.31927436 |
49 | MP0006276_abnormal_autonomic_nervous | 1.30070685 |
50 | MP0001502_abnormal_circadian_rhythm | 1.29239597 |
51 | MP0001986_abnormal_taste_sensitivity | 1.29042189 |
52 | MP0003724_increased_susceptibility_to | 1.26713228 |
53 | MP0001905_abnormal_dopamine_level | 1.24523707 |
54 | MP0002638_abnormal_pupillary_reflex | 1.17735542 |
55 | MP0003172_abnormal_lysosome_physiology | 1.16373763 |
56 | MP0005645_abnormal_hypothalamus_physiol | 1.16122175 |
57 | MP0001188_hyperpigmentation | 1.15843748 |
58 | MP0002152_abnormal_brain_morphology | 1.10698978 |
59 | MP0003631_nervous_system_phenotype | 1.09866346 |
60 | MP0001348_abnormal_lacrimal_gland | 1.05948853 |
61 | MP0003075_altered_response_to | 1.05683659 |
62 | MP0003122_maternal_imprinting | 1.03525562 |
63 | MP0004133_heterotaxia | 1.00957560 |
64 | MP0004142_abnormal_muscle_tone | 1.00462883 |
65 | MP0004130_abnormal_muscle_cell | 0.99177243 |
66 | MP0002069_abnormal_eating/drinking_beha | 0.99092404 |
67 | MP0003436_decreased_susceptibility_to | 0.99046871 |
68 | MP0008874_decreased_physiological_sensi | 0.98913418 |
69 | MP0008872_abnormal_physiological_respon | 0.97922537 |
70 | MP0008961_abnormal_basal_metabolism | 0.95722914 |
71 | MP0010386_abnormal_urinary_bladder | 0.93875161 |
72 | MP0002837_dystrophic_cardiac_calcinosis | 0.92395598 |
73 | MP0004145_abnormal_muscle_electrophysio | 0.89658866 |
74 | MP0001177_atelectasis | 0.88780911 |
75 | MP0005377_hearing/vestibular/ear_phenot | 0.88684772 |
76 | MP0003878_abnormal_ear_physiology | 0.88684772 |
77 | MP0005535_abnormal_body_temperature | 0.88061254 |
78 | MP0004085_abnormal_heartbeat | 0.87894302 |
79 | MP0004510_myositis | 0.83761484 |
80 | MP0000013_abnormal_adipose_tissue | 0.83334520 |
81 | MP0000751_myopathy | 0.81966844 |
82 | MP0005409_darkened_coat_color | 0.81932388 |
83 | MP0002229_neurodegeneration | 0.81162773 |
84 | MP0004742_abnormal_vestibular_system | 0.79784872 |
85 | MP0000604_amyloidosis | 0.79466488 |
86 | MP0000631_abnormal_neuroendocrine_gland | 0.78777026 |
87 | MP0000569_abnormal_digit_pigmentation | 0.78690852 |
88 | MP0003283_abnormal_digestive_organ | 0.78249967 |
89 | MP0009278_abnormal_bone_marrow | 0.77992161 |
90 | MP0005248_abnormal_Harderian_gland | 0.77853649 |
91 | MP0003938_abnormal_ear_development | 0.77756738 |
92 | MP0005394_taste/olfaction_phenotype | 0.77309865 |
93 | MP0005499_abnormal_olfactory_system | 0.77309865 |
94 | MP0003011_delayed_dark_adaptation | 0.77066687 |
95 | MP0001963_abnormal_hearing_physiology | 0.76927659 |
96 | MP0002419_abnormal_innate_immunity | 0.76670360 |
97 | MP0005551_abnormal_eye_electrophysiolog | 0.75610756 |
98 | MP0005410_abnormal_fertilization | 0.75496146 |
99 | MP0001664_abnormal_digestion | 0.74910362 |
100 | MP0003632_abnormal_nervous_system | 0.71136298 |
101 | MP0003634_abnormal_glial_cell | 0.70425135 |
102 | MP0000920_abnormal_myelination | 0.69871454 |
103 | MP0009379_abnormal_foot_pigmentation | 0.68913132 |
104 | MP0000026_abnormal_inner_ear | 0.68082003 |
105 | MP0005310_abnormal_salivary_gland | 0.67397412 |
106 | MP0002234_abnormal_pharynx_morphology | 0.67313085 |
107 | MP0001485_abnormal_pinna_reflex | 0.65794766 |
108 | MP0003690_abnormal_glial_cell | 0.64693502 |
109 | MP0005167_abnormal_blood-brain_barrier | 0.63748640 |
110 | MP0002752_abnormal_somatic_nervous | 0.63015811 |
111 | MP0004484_altered_response_of | 0.62670319 |
112 | MP0006292_abnormal_olfactory_placode | 0.62545119 |
113 | MP0010234_abnormal_vibrissa_follicle | 0.61899704 |
114 | MP0002090_abnormal_vision | 0.60482294 |
115 | MP0002277_abnormal_respiratory_mucosa | 0.59349539 |
116 | MP0002876_abnormal_thyroid_physiology | 0.58034190 |
117 | MP0002928_abnormal_bile_duct | 0.57877061 |
118 | MP0003861_abnormal_nervous_system | 0.57561807 |
119 | MP0006082_CNS_inflammation | 0.57503297 |
120 | MP0005623_abnormal_meninges_morphology | 0.57460065 |
121 | MP0004043_abnormal_pH_regulation | 0.57104461 |
122 | MP0004215_abnormal_myocardial_fiber | 0.56967800 |
123 | MP0005025_abnormal_response_to | 0.54777742 |
124 | MP0005187_abnormal_penis_morphology | 0.54732279 |
125 | MP0003890_abnormal_embryonic-extraembry | 0.54495645 |
126 | MP0003137_abnormal_impulse_conducting | 0.54243008 |
127 | MP0001943_abnormal_respiration | 0.53501920 |
128 | MP0001765_abnormal_ion_homeostasis | 0.51529219 |
129 | MP0010769_abnormal_survival | 0.50091744 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 8.49564584 |
2 | Myokymia (HP:0002411) | 7.36246188 |
3 | Focal seizures (HP:0007359) | 6.04883702 |
4 | Visual hallucinations (HP:0002367) | 5.51980772 |
5 | Epileptic encephalopathy (HP:0200134) | 5.42857727 |
6 | Atonic seizures (HP:0010819) | 4.73526909 |
7 | Febrile seizures (HP:0002373) | 4.36394462 |
8 | Absence seizures (HP:0002121) | 4.22990309 |
9 | Broad-based gait (HP:0002136) | 3.98464602 |
10 | Generalized tonic-clonic seizures (HP:0002069) | 3.95972038 |
11 | Progressive cerebellar ataxia (HP:0002073) | 3.95420923 |
12 | Dialeptic seizures (HP:0011146) | 3.93656335 |
13 | Poor eye contact (HP:0000817) | 3.93177992 |
14 | Hyperventilation (HP:0002883) | 3.91205419 |
15 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.58799325 |
16 | Supranuclear gaze palsy (HP:0000605) | 3.58592268 |
17 | Action tremor (HP:0002345) | 3.51986554 |
18 | Amblyopia (HP:0000646) | 3.51531998 |
19 | Impaired social interactions (HP:0000735) | 3.36950941 |
20 | Abnormal social behavior (HP:0012433) | 3.36950941 |
21 | Gaze-evoked nystagmus (HP:0000640) | 3.35660346 |
22 | Depression (HP:0000716) | 3.27614858 |
23 | Hypochromic microcytic anemia (HP:0004840) | 3.21758383 |
24 | Ankle clonus (HP:0011448) | 3.20714672 |
25 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.16343131 |
26 | Anxiety (HP:0000739) | 3.13748740 |
27 | Dysmetria (HP:0001310) | 3.12228134 |
28 | Dysdiadochokinesis (HP:0002075) | 3.12165033 |
29 | Papilledema (HP:0001085) | 3.02794034 |
30 | Truncal ataxia (HP:0002078) | 3.02713292 |
31 | Recurrent bacterial skin infections (HP:0005406) | 2.95723963 |
32 | Cerebral inclusion bodies (HP:0100314) | 2.95118038 |
33 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.94705843 |
34 | Excessive salivation (HP:0003781) | 2.91702081 |
35 | Drooling (HP:0002307) | 2.91702081 |
36 | Impaired smooth pursuit (HP:0007772) | 2.88474842 |
37 | Epileptiform EEG discharges (HP:0011182) | 2.86550620 |
38 | Disinhibition (HP:0000734) | 2.85365282 |
39 | Recurrent abscess formation (HP:0002722) | 2.84931879 |
40 | Abnormal eating behavior (HP:0100738) | 2.79998580 |
41 | Stereotypic behavior (HP:0000733) | 2.77859037 |
42 | Hepatoblastoma (HP:0002884) | 2.77542256 |
43 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.76193901 |
44 | Abnormality of the lower motor neuron (HP:0002366) | 2.73747844 |
45 | Torticollis (HP:0000473) | 2.72476127 |
46 | Genetic anticipation (HP:0003743) | 2.70073749 |
47 | Urinary urgency (HP:0000012) | 2.68935204 |
48 | Postural instability (HP:0002172) | 2.68386924 |
49 | Megalencephaly (HP:0001355) | 2.67261615 |
50 | Absent speech (HP:0001344) | 2.65866167 |
51 | Hemiparesis (HP:0001269) | 2.65742329 |
52 | EEG with generalized epileptiform discharges (HP:0011198) | 2.65178888 |
53 | Focal dystonia (HP:0004373) | 2.62158975 |
54 | Neurofibrillary tangles (HP:0002185) | 2.61607219 |
55 | Mutism (HP:0002300) | 2.61095590 |
56 | Eczematoid dermatitis (HP:0000976) | 2.57969734 |
57 | Spastic gait (HP:0002064) | 2.55118050 |
58 | Diplopia (HP:0000651) | 2.51491879 |
59 | Abnormality of binocular vision (HP:0011514) | 2.51491879 |
60 | Hypsarrhythmia (HP:0002521) | 2.51011117 |
61 | Retrobulbar optic neuritis (HP:0100654) | 2.49196640 |
62 | Optic neuritis (HP:0100653) | 2.49196640 |
63 | Scanning speech (HP:0002168) | 2.48706789 |
64 | Insidious onset (HP:0003587) | 2.45803231 |
65 | Termporal pattern (HP:0011008) | 2.45803231 |
66 | Impaired vibratory sensation (HP:0002495) | 2.44165774 |
67 | Bradykinesia (HP:0002067) | 2.41162432 |
68 | Akinesia (HP:0002304) | 2.37064338 |
69 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.36544600 |
70 | Orchitis (HP:0100796) | 2.35773607 |
71 | Myositis (HP:0100614) | 2.35086004 |
72 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.33175638 |
73 | Obstructive sleep apnea (HP:0002870) | 2.32527736 |
74 | Annular pancreas (HP:0001734) | 2.30637345 |
75 | Craniofacial dystonia (HP:0012179) | 2.28862410 |
76 | Peripheral hypomyelination (HP:0007182) | 2.28057736 |
77 | Intention tremor (HP:0002080) | 2.24636519 |
78 | Status epilepticus (HP:0002133) | 2.24557025 |
79 | Inability to walk (HP:0002540) | 2.24178239 |
80 | Stomatitis (HP:0010280) | 2.23592866 |
81 | Progressive inability to walk (HP:0002505) | 2.23285509 |
82 | Abnormality of macrophages (HP:0004311) | 2.22855477 |
83 | Generalized myoclonic seizures (HP:0002123) | 2.20872647 |
84 | Delusions (HP:0000746) | 2.20619981 |
85 | Pointed chin (HP:0000307) | 2.17414307 |
86 | Dysmetric saccades (HP:0000641) | 2.17230818 |
87 | Fetal akinesia sequence (HP:0001989) | 2.12461758 |
88 | Lower limb muscle weakness (HP:0007340) | 2.10484533 |
89 | Diminished motivation (HP:0000745) | 2.08536189 |
90 | Lower limb amyotrophy (HP:0007210) | 2.07458727 |
91 | Resting tremor (HP:0002322) | 2.06519586 |
92 | Hemiplegia (HP:0002301) | 2.05818197 |
93 | Abnormality of the corticospinal tract (HP:0002492) | 2.04116845 |
94 | Incomplete penetrance (HP:0003829) | 2.03527476 |
95 | Restlessness (HP:0000711) | 2.02715374 |
96 | Protruding tongue (HP:0010808) | 2.02360506 |
97 | Hypochromic anemia (HP:0001931) | 2.01496880 |
98 | Anomalous pulmonary venous return (HP:0010772) | 2.01123901 |
99 | Ankyloglossia (HP:0010296) | 2.00830522 |
100 | Ventricular fibrillation (HP:0001663) | 1.99938941 |
101 | Failure to thrive in infancy (HP:0001531) | 1.98911894 |
102 | Polyphagia (HP:0002591) | 1.97762880 |
103 | Abnormality of salivation (HP:0100755) | 1.97512056 |
104 | Agnosia (HP:0010524) | 1.95513180 |
105 | Obstructive lung disease (HP:0006536) | 1.92121654 |
106 | Chronic obstructive pulmonary disease (HP:0006510) | 1.92121654 |
107 | Gait ataxia (HP:0002066) | 1.91413333 |
108 | Intellectual disability, severe (HP:0010864) | 1.88864473 |
109 | Insomnia (HP:0100785) | 1.87837388 |
110 | Spastic tetraplegia (HP:0002510) | 1.86372360 |
111 | Blue irides (HP:0000635) | 1.85816965 |
112 | Pachygyria (HP:0001302) | 1.84232021 |
113 | Lower limb asymmetry (HP:0100559) | 1.83699044 |
114 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.82057882 |
115 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.82057882 |
116 | Sleep apnea (HP:0010535) | 1.81942549 |
117 | Spastic tetraparesis (HP:0001285) | 1.80850801 |
118 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.80772055 |
119 | Inappropriate behavior (HP:0000719) | 1.80515841 |
120 | Amyotrophic lateral sclerosis (HP:0007354) | 1.80420673 |
121 | Mediastinal lymphadenopathy (HP:0100721) | 1.79126240 |
122 | Memory impairment (HP:0002354) | 1.78841034 |
123 | Gait imbalance (HP:0002141) | 1.78324913 |
124 | Psychosis (HP:0000709) | 1.77745460 |
125 | Sporadic (HP:0003745) | 1.77547767 |
126 | Deep palmar crease (HP:0006191) | 1.77412814 |
127 | Abnormal EKG (HP:0003115) | 1.77310965 |
128 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.74925557 |
129 | Agitation (HP:0000713) | 1.73449134 |
130 | Autism (HP:0000717) | 1.73250540 |
131 | Rapidly progressive (HP:0003678) | 1.73226080 |
132 | Specific learning disability (HP:0001328) | 1.73130892 |
133 | Limb dystonia (HP:0002451) | 1.71965674 |
134 | Apathy (HP:0000741) | 1.71195631 |
135 | Intellectual disability, profound (HP:0002187) | 1.70664478 |
136 | Neuronal loss in central nervous system (HP:0002529) | 1.70115826 |
137 | Abnormality of the periventricular white matter (HP:0002518) | 1.69721231 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 5.87699984 |
2 | NTRK3 | 4.49452292 |
3 | MAP3K9 | 3.67659115 |
4 | DAPK2 | 3.28664022 |
5 | MAP3K4 | 2.75811582 |
6 | PRKD3 | 2.67983988 |
7 | RIPK4 | 2.67335348 |
8 | MARK1 | 2.61827162 |
9 | MINK1 | 2.50010806 |
10 | MAP2K7 | 2.40949165 |
11 | DYRK2 | 2.16780277 |
12 | PAK6 | 2.14133344 |
13 | DAPK1 | 2.14074343 |
14 | CASK | 2.10260630 |
15 | KSR2 | 2.07271728 |
16 | KSR1 | 1.85310928 |
17 | MAP3K11 | 1.84797105 |
18 | TNK2 | 1.82946892 |
19 | CAMKK1 | 1.75368026 |
20 | MAP3K12 | 1.72605551 |
21 | CDK19 | 1.68968585 |
22 | PLK2 | 1.68016342 |
23 | MAP2K4 | 1.66931723 |
24 | NTRK2 | 1.66691093 |
25 | SIK2 | 1.62297385 |
26 | NTRK1 | 1.58406696 |
27 | CDK5 | 1.57615822 |
28 | TNIK | 1.51143227 |
29 | CAMK1D | 1.51047272 |
30 | PRPF4B | 1.40931131 |
31 | GRK5 | 1.35041892 |
32 | MAPK13 | 1.31260444 |
33 | ARAF | 1.30824402 |
34 | FES | 1.26357195 |
35 | BMPR2 | 1.25663973 |
36 | MAP3K13 | 1.18890258 |
37 | PNCK | 1.18341813 |
38 | TYRO3 | 1.16056451 |
39 | STK38 | 1.13999045 |
40 | PRKCG | 1.13666572 |
41 | PTK2B | 1.11294245 |
42 | MAP3K2 | 1.07446751 |
43 | UHMK1 | 1.05454286 |
44 | DYRK1B | 1.01456104 |
45 | BLK | 1.00153285 |
46 | CAMK2A | 0.98421954 |
47 | CSK | 0.97539175 |
48 | TAOK1 | 0.97041783 |
49 | RAF1 | 0.91810583 |
50 | CAMKK2 | 0.90901837 |
51 | CDK18 | 0.89819693 |
52 | CAMK1 | 0.89112171 |
53 | IRAK4 | 0.88796142 |
54 | CCNB1 | 0.88048685 |
55 | CDK15 | 0.86492560 |
56 | STK11 | 0.86068020 |
57 | CAMK2B | 0.85152455 |
58 | EPHB1 | 0.82346563 |
59 | FGR | 0.81451885 |
60 | CDK14 | 0.81261668 |
61 | OXSR1 | 0.80995418 |
62 | PRKCH | 0.79598792 |
63 | CDK11A | 0.75695661 |
64 | ICK | 0.73325608 |
65 | DYRK3 | 0.72794566 |
66 | SGK223 | 0.71958834 |
67 | SGK494 | 0.71958834 |
68 | DYRK1A | 0.70438972 |
69 | SGK1 | 0.69459410 |
70 | RET | 0.68664551 |
71 | NME1 | 0.68263900 |
72 | MARK2 | 0.66209807 |
73 | PDK1 | 0.65632693 |
74 | PDPK1 | 0.64591860 |
75 | SYK | 0.64195387 |
76 | MAP2K3 | 0.62487611 |
77 | RPS6KA2 | 0.62456798 |
78 | DAPK3 | 0.61034606 |
79 | JAK2 | 0.58359326 |
80 | CSNK1G3 | 0.58213200 |
81 | PKN1 | 0.56814023 |
82 | PAK3 | 0.56263052 |
83 | SGK2 | 0.55554303 |
84 | CSNK1G2 | 0.54618178 |
85 | SIK3 | 0.52086299 |
86 | GRK6 | 0.50375184 |
87 | PHKG1 | 0.49631844 |
88 | PHKG2 | 0.49631844 |
89 | PRKCZ | 0.49298749 |
90 | TESK1 | 0.49149164 |
91 | LATS2 | 0.48591214 |
92 | EPHA3 | 0.48348988 |
93 | YES1 | 0.48062221 |
94 | HCK | 0.47782436 |
95 | GRK7 | 0.46929249 |
96 | CSNK1A1L | 0.46817707 |
97 | MAP3K1 | 0.46798618 |
98 | PRKCE | 0.46380701 |
99 | FYN | 0.45851886 |
100 | MAPK8 | 0.44375544 |
101 | CAMK4 | 0.44305980 |
102 | RPS6KA3 | 0.44193680 |
103 | SGK3 | 0.43765081 |
104 | MAPK4 | 0.43517434 |
105 | ALK | 0.42238606 |
106 | PRKD2 | 0.40009149 |
107 | PRKG1 | 0.39922076 |
108 | RIPK1 | 0.39598514 |
109 | CDC42BPA | 0.38108313 |
110 | NEK6 | 0.37764044 |
111 | MAPK10 | 0.37739882 |
112 | WNK1 | 0.37664529 |
113 | CAMK2D | 0.36424713 |
114 | MAP3K6 | 0.36416968 |
115 | CAMK1G | 0.36369415 |
116 | MAP3K7 | 0.36194591 |
117 | MAP2K1 | 0.35725936 |
118 | DMPK | 0.35403066 |
119 | LYN | 0.35277486 |
120 | BRAF | 0.34475317 |
121 | PINK1 | 0.33803330 |
122 | BCR | 0.33216098 |
123 | BRSK1 | 0.30416096 |
124 | PRKCB | 0.29411141 |
125 | FER | 0.29199259 |
126 | CAMK2G | 0.28307340 |
127 | MAPK12 | 0.27546910 |
128 | ROCK2 | 0.27298505 |
129 | WNK3 | 0.26462454 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.66218899 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.17997626 |
3 | Long-term potentiation_Homo sapiens_hsa04720 | 2.94661722 |
4 | Olfactory transduction_Homo sapiens_hsa04740 | 2.89349638 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.80031498 |
6 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.71895669 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.68964670 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.67641837 |
9 | Morphine addiction_Homo sapiens_hsa05032 | 2.57675964 |
10 | GABAergic synapse_Homo sapiens_hsa04727 | 2.53962067 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 2.26625426 |
12 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.25893942 |
13 | Insulin secretion_Homo sapiens_hsa04911 | 2.13677264 |
14 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.09295974 |
15 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.96359944 |
16 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.95317560 |
17 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.94680587 |
18 | Renin secretion_Homo sapiens_hsa04924 | 1.82104622 |
19 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.78575073 |
20 | Taste transduction_Homo sapiens_hsa04742 | 1.73822255 |
21 | Cocaine addiction_Homo sapiens_hsa05030 | 1.71453228 |
22 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.69070041 |
23 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.67609041 |
24 | Long-term depression_Homo sapiens_hsa04730 | 1.66637703 |
25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.65450081 |
26 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.49222829 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.49176375 |
28 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.37553559 |
29 | Gap junction_Homo sapiens_hsa04540 | 1.37444444 |
30 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.32313398 |
31 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.32228108 |
32 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.31361447 |
33 | Glioma_Homo sapiens_hsa05214 | 1.25748559 |
34 | Axon guidance_Homo sapiens_hsa04360 | 1.22363210 |
35 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.21345710 |
36 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.20506856 |
37 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.16533485 |
38 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.16111465 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.16110370 |
40 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.12100955 |
41 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.09077221 |
42 | Tuberculosis_Homo sapiens_hsa05152 | 1.08608365 |
43 | Melanogenesis_Homo sapiens_hsa04916 | 1.08495931 |
44 | Phagosome_Homo sapiens_hsa04145 | 1.04483327 |
45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.00921042 |
46 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.98855025 |
47 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.97368593 |
48 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.97288550 |
49 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.94848943 |
50 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.93925265 |
51 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.90767095 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.88534880 |
53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.87924507 |
54 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87550484 |
55 | Leishmaniasis_Homo sapiens_hsa05140 | 0.84803609 |
56 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.84202327 |
57 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.83528024 |
58 | Phototransduction_Homo sapiens_hsa04744 | 0.81475393 |
59 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.81458844 |
60 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.80957017 |
61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.79903587 |
62 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.79809043 |
63 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.76692391 |
64 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.74699860 |
65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.74464038 |
66 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.74429493 |
67 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.73736278 |
68 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.73247760 |
69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.72477694 |
70 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.72343365 |
71 | Salmonella infection_Homo sapiens_hsa05132 | 0.72095407 |
72 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.70902760 |
73 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.69597661 |
74 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.69134555 |
75 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66731029 |
76 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.64629792 |
77 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.64150383 |
78 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.63894431 |
79 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.62646594 |
80 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.62214825 |
81 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.58130225 |
82 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.54888298 |
83 | Alcoholism_Homo sapiens_hsa05034 | 0.54541190 |
84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.53815527 |
85 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.53259337 |
86 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.51537961 |
87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.50826352 |
88 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.50803321 |
89 | Circadian rhythm_Homo sapiens_hsa04710 | 0.50040643 |
90 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.49878444 |
91 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.49610713 |
92 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48667006 |
93 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.48608443 |
94 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.46072592 |
95 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.45754628 |
96 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.45633375 |
97 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.45571636 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.43496362 |
99 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.43257664 |
100 | Alzheimers disease_Homo sapiens_hsa05010 | 0.42784990 |
101 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.42407775 |
102 | Parkinsons disease_Homo sapiens_hsa05012 | 0.42196698 |
103 | Platelet activation_Homo sapiens_hsa04611 | 0.41961237 |
104 | Endometrial cancer_Homo sapiens_hsa05213 | 0.39913930 |
105 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.39769845 |
106 | Prion diseases_Homo sapiens_hsa05020 | 0.39425587 |
107 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.37409681 |
108 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.37385958 |
109 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.36567366 |
110 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.34695099 |
111 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34389126 |
112 | Bile secretion_Homo sapiens_hsa04976 | 0.32654884 |
113 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.32412048 |
114 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.29830879 |
115 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.28696461 |
116 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.24128238 |
117 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.23813301 |
118 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.23577373 |
119 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.23556743 |
120 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23279953 |
121 | Colorectal cancer_Homo sapiens_hsa05210 | 0.22877378 |