Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 9.97961877 |
2 | transcytosis (GO:0045056) | 8.80184618 |
3 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 8.70783402 |
4 | positive regulation of p38MAPK cascade (GO:1900745) | 7.98630495 |
5 | cobalamin metabolic process (GO:0009235) | 7.79994687 |
6 | COPI coating of Golgi vesicle (GO:0048205) | 7.75205227 |
7 | Golgi transport vesicle coating (GO:0048200) | 7.75205227 |
8 | peptidyl-proline hydroxylation (GO:0019511) | 6.96288196 |
9 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 6.51655806 |
10 | negative regulation of digestive system process (GO:0060457) | 6.34204081 |
11 | oligosaccharide biosynthetic process (GO:0009312) | 6.16059777 |
12 | regulation of p38MAPK cascade (GO:1900744) | 6.13644549 |
13 | glycolipid catabolic process (GO:0019377) | 6.01125195 |
14 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 5.90066750 |
15 | regulation of phospholipase A2 activity (GO:0032429) | 5.83038080 |
16 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.72875099 |
17 | innate immune response in mucosa (GO:0002227) | 5.66744277 |
18 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 5.65230342 |
19 | positive regulation of nuclease activity (GO:0032075) | 5.63835205 |
20 | cysteine metabolic process (GO:0006534) | 5.53718833 |
21 | protein hydroxylation (GO:0018126) | 5.43478362 |
22 | protein maturation by protein folding (GO:0022417) | 5.30534157 |
23 | proline biosynthetic process (GO:0006561) | 5.30104641 |
24 | valine metabolic process (GO:0006573) | 5.30073838 |
25 | icosanoid transport (GO:0071715) | 5.22025391 |
26 | fatty acid derivative transport (GO:1901571) | 5.22025391 |
27 | endoplasmic reticulum unfolded protein response (GO:0030968) | 5.19565450 |
28 | * intestinal absorption (GO:0050892) | 5.14765599 |
29 | regulation of nuclease activity (GO:0032069) | 5.12191414 |
30 | lactation (GO:0007595) | 5.08891925 |
31 | nucleobase catabolic process (GO:0046113) | 5.08072169 |
32 | cellular response to unfolded protein (GO:0034620) | 5.03349425 |
33 | response to endoplasmic reticulum stress (GO:0034976) | 5.00337370 |
34 | branched-chain amino acid catabolic process (GO:0009083) | 4.96667478 |
35 | endocrine pancreas development (GO:0031018) | 4.91462756 |
36 | zinc ion transport (GO:0006829) | 4.89032645 |
37 | ER-nucleus signaling pathway (GO:0006984) | 4.83502021 |
38 | COPII vesicle coating (GO:0048208) | 4.83405379 |
39 | intestinal epithelial cell development (GO:0060576) | 4.80153304 |
40 | regulation of endothelial cell differentiation (GO:0045601) | 4.79586051 |
41 | regulation of keratinocyte differentiation (GO:0045616) | 4.77523962 |
42 | cellular response to topologically incorrect protein (GO:0035967) | 4.76668407 |
43 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 4.56338926 |
44 | branched-chain amino acid metabolic process (GO:0009081) | 4.55866601 |
45 | mucosal immune response (GO:0002385) | 4.55628460 |
46 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 4.55119707 |
47 | negative regulation of epithelial cell differentiation (GO:0030857) | 4.54204670 |
48 | regulation of keratinocyte proliferation (GO:0010837) | 4.47728509 |
49 | myeloid leukocyte mediated immunity (GO:0002444) | 4.47515160 |
50 | cellular modified amino acid catabolic process (GO:0042219) | 4.39208270 |
51 | 4-hydroxyproline metabolic process (GO:0019471) | 4.38385505 |
52 | phosphatidic acid biosynthetic process (GO:0006654) | 4.36061152 |
53 | phosphatidic acid metabolic process (GO:0046473) | 4.36061152 |
54 | mitochondrial calcium ion transport (GO:0006851) | 4.23323511 |
55 | signal peptide processing (GO:0006465) | 4.22084775 |
56 | regulation of acrosome reaction (GO:0060046) | 4.21722786 |
57 | maintenance of protein localization in organelle (GO:0072595) | 4.21518732 |
58 | negative regulation of execution phase of apoptosis (GO:1900118) | 4.17959170 |
59 | ER overload response (GO:0006983) | 4.15768871 |
60 | organ or tissue specific immune response (GO:0002251) | 4.12151465 |
61 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 4.07569091 |
62 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.07240371 |
63 | response to unfolded protein (GO:0006986) | 4.05981306 |
64 | homocysteine metabolic process (GO:0050667) | 4.03822557 |
65 | phosphatidylserine metabolic process (GO:0006658) | 4.01729283 |
66 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.91672795 |
67 | regulation of vasculogenesis (GO:2001212) | 3.90359509 |
68 | alditol phosphate metabolic process (GO:0052646) | 3.89560115 |
69 | protein N-linked glycosylation via asparagine (GO:0018279) | 3.89458412 |
70 | response to topologically incorrect protein (GO:0035966) | 3.89368767 |
71 | peptidyl-asparagine modification (GO:0018196) | 3.87742367 |
72 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.84703828 |
73 | response to phenylpropanoid (GO:0080184) | 3.81711892 |
74 | regulation of cholesterol homeostasis (GO:2000188) | 3.79785386 |
75 | regulation of sequestering of triglyceride (GO:0010889) | 3.76076076 |
76 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.74417837 |
77 | glutamine metabolic process (GO:0006541) | 3.71854881 |
78 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 3.65062390 |
79 | long-chain fatty acid transport (GO:0015909) | 3.62335206 |
80 | positive regulation of heat generation (GO:0031652) | 3.61015936 |
81 | * secretion by tissue (GO:0032941) | 3.60959457 |
82 | leukotriene biosynthetic process (GO:0019370) | 3.60652970 |
83 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.59595448 |
84 | aspartate family amino acid catabolic process (GO:0009068) | 3.59257954 |
85 | protein N-linked glycosylation (GO:0006487) | 3.57111673 |
86 | * digestive system process (GO:0022600) | 3.56533239 |
87 | serine family amino acid biosynthetic process (GO:0009070) | 3.53452386 |
88 | vesicle coating (GO:0006901) | 3.52841136 |
89 | water-soluble vitamin metabolic process (GO:0006767) | 3.46428551 |
90 | endothelial cell migration (GO:0043542) | 3.45088022 |
91 | negative regulation of protein kinase B signaling (GO:0051898) | 3.42475115 |
92 | creatine metabolic process (GO:0006600) | 3.39784079 |
93 | proline metabolic process (GO:0006560) | 3.39089711 |
94 | regulation of fever generation (GO:0031620) | 3.37996717 |
95 | Golgi organization (GO:0007030) | 3.36004086 |
96 | leukotriene metabolic process (GO:0006691) | 3.34562395 |
97 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 3.32975161 |
98 | antibacterial humoral response (GO:0019731) | 3.31667390 |
99 | ectoderm development (GO:0007398) | 3.31191494 |
100 | GDP-mannose metabolic process (GO:0019673) | 3.30338298 |
101 | phospholipid catabolic process (GO:0009395) | 3.29316761 |
102 | acute-phase response (GO:0006953) | 3.24804844 |
103 | coenzyme catabolic process (GO:0009109) | 3.24361659 |
104 | biotin metabolic process (GO:0006768) | 3.23030050 |
105 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.22696550 |
106 | cell redox homeostasis (GO:0045454) | 3.22439336 |
107 | mammary gland epithelial cell differentiation (GO:0060644) | 3.21236395 |
108 | * membrane lipid catabolic process (GO:0046466) | 3.20666169 |
109 | neutrophil mediated immunity (GO:0002446) | 3.18212186 |
110 | polarized epithelial cell differentiation (GO:0030859) | 3.16882910 |
111 | maintenance of gastrointestinal epithelium (GO:0030277) | 3.16503564 |
112 | pancreas development (GO:0031016) | 3.15212034 |
113 | phosphatidylglycerol metabolic process (GO:0046471) | 3.14952033 |
114 | mitochondrion distribution (GO:0048311) | 3.08837382 |
115 | * body fluid secretion (GO:0007589) | 3.08722087 |
116 | antimicrobial humoral response (GO:0019730) | 3.07181018 |
117 | * cholesterol transport (GO:0030301) | 3.06268983 |
118 | * sterol transport (GO:0015918) | 3.06268983 |
119 | atrioventricular valve morphogenesis (GO:0003181) | 3.05558464 |
120 | cellular protein catabolic process (GO:0044257) | 3.02723015 |
121 | L-phenylalanine catabolic process (GO:0006559) | 3.02380706 |
122 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.02380706 |
123 | retinoid metabolic process (GO:0001523) | 2.99885162 |
124 | defense response to Gram-positive bacterium (GO:0050830) | 2.97442776 |
125 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.94058965 |
126 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.93185958 |
127 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.86059908 |
128 | icosanoid secretion (GO:0032309) | 2.84074697 |
129 | arachidonic acid secretion (GO:0050482) | 2.84074697 |
130 | diterpenoid metabolic process (GO:0016101) | 2.83737964 |
131 | regulation of apoptotic cell clearance (GO:2000425) | 2.83269912 |
132 | positive regulation of lipid storage (GO:0010884) | 2.82564431 |
133 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.81156885 |
134 | L-phenylalanine metabolic process (GO:0006558) | 2.81156885 |
135 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902175) | 2.80635477 |
136 | fatty acid transport (GO:0015908) | 2.76188474 |
137 | L-serine metabolic process (GO:0006563) | 2.74650008 |
138 | macroautophagy (GO:0016236) | 2.72939969 |
139 | columnar/cuboidal epithelial cell development (GO:0002066) | 2.72702053 |
140 | regulation of heat generation (GO:0031650) | 2.70518137 |
141 | serine family amino acid metabolic process (GO:0009069) | 2.70470663 |
142 | regulation of oxidative stress-induced cell death (GO:1903201) | 2.70069695 |
143 | negative regulation of epidermis development (GO:0045683) | 2.69444450 |
144 | phospholipid homeostasis (GO:0055091) | 2.68599022 |
145 | regulation of epidermal cell differentiation (GO:0045604) | 2.68344363 |
146 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.67622809 |
147 | glandular epithelial cell differentiation (GO:0002067) | 2.66011330 |
148 | peptide catabolic process (GO:0043171) | 2.65939243 |
149 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.65605322 |
150 | regulation of digestive system process (GO:0044058) | 2.65376110 |
151 | epithelial cell migration (GO:0010631) | 2.62416471 |
152 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.60039975 |
153 | vitamin metabolic process (GO:0006766) | 2.58280284 |
154 | regulation of phospholipid biosynthetic process (GO:0071071) | 2.55868863 |
155 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.55400758 |
156 | establishment of apical/basal cell polarity (GO:0035089) | 2.54197015 |
157 | membrane repolarization during action potential (GO:0086011) | 2.53831698 |
158 | endoplasmic reticulum organization (GO:0007029) | 2.53356373 |
159 | tetrapyrrole metabolic process (GO:0033013) | 2.52089683 |
160 | icosanoid biosynthetic process (GO:0046456) | 2.48937453 |
161 | fatty acid derivative biosynthetic process (GO:1901570) | 2.48937453 |
162 | peptidyl-proline modification (GO:0018208) | 2.48611652 |
163 | temperature homeostasis (GO:0001659) | 2.47278093 |
164 | terpenoid metabolic process (GO:0006721) | 2.46314139 |
165 | exocrine pancreas development (GO:0031017) | 16.4512471 |
166 | * digestion (GO:0007586) | 12.6930079 |
167 | protein retention in ER lumen (GO:0006621) | 12.2996645 |
168 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 11.7416363 |
169 | * intestinal cholesterol absorption (GO:0030299) | 10.8843445 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.50732138 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.21527287 |
3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.97962912 |
4 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.84129612 |
5 | GATA1_22025678_ChIP-Seq_K562_Human | 3.05549318 |
6 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.83463122 |
7 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.83214900 |
8 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.74570016 |
9 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.67835125 |
10 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.67387515 |
11 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.64539357 |
12 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.58303774 |
13 | GATA4_25053715_ChIP-Seq_YYC3_Human | 2.57975326 |
14 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.53697871 |
15 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 2.49454366 |
16 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.40366205 |
17 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.23271087 |
18 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.17825303 |
19 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.87155884 |
20 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.75443101 |
21 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.74920887 |
22 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.72568416 |
23 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.61179032 |
24 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.60565114 |
25 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.59711340 |
26 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.59060918 |
27 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.54803749 |
28 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.54357810 |
29 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.52542634 |
30 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.51622052 |
31 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.45332576 |
32 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.44067802 |
33 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.42800708 |
34 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.40288205 |
35 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.39892116 |
36 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.35156740 |
37 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.34557268 |
38 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.32398482 |
39 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.31034164 |
40 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.30985144 |
41 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.29582288 |
42 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.26650457 |
43 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.26480973 |
44 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.26194289 |
45 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.25558200 |
46 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.24049610 |
47 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.23932118 |
48 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 1.19368321 |
49 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.19130249 |
50 | NFYA_21822215_ChIP-Seq_K562_Human | 1.19084092 |
51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.19052013 |
52 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.18546636 |
53 | ATF3_27146783_Chip-Seq_COLON_Human | 1.17933094 |
54 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.16393952 |
55 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.16106082 |
56 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.15013369 |
57 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.15013369 |
58 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.15013369 |
59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.14369997 |
60 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.11732525 |
61 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.11208163 |
62 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.10535289 |
63 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.09661433 |
64 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.09382616 |
65 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.08782139 |
66 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.08663916 |
67 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.08390946 |
68 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.08148965 |
69 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.08118854 |
70 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.07685293 |
71 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07470493 |
72 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.07210756 |
73 | P68_20966046_ChIP-Seq_HELA_Human | 1.06985678 |
74 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.05583484 |
75 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.05583484 |
76 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.05262148 |
77 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.04636034 |
78 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.04545247 |
79 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.04173753 |
80 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.03883386 |
81 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.03503774 |
82 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.03308143 |
83 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.03051295 |
84 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02342237 |
85 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.02130942 |
86 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.02127888 |
87 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.01625639 |
88 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.01328339 |
89 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.99471592 |
90 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.99443116 |
91 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.97656911 |
92 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.96393758 |
93 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95270142 |
94 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.94700962 |
95 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.94167443 |
96 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.94110602 |
97 | KDM2B_26808549_Chip-Seq_K562_Human | 0.92716168 |
98 | GATA1_19941826_ChIP-Seq_K562_Human | 0.90621419 |
99 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.89262952 |
100 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.87744023 |
101 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.86913712 |
102 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.86251839 |
103 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.85872039 |
104 | * ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.85512825 |
105 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.85416375 |
106 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.84256943 |
107 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.82867228 |
108 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.82262925 |
109 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.82238398 |
110 | ERA_21632823_ChIP-Seq_H3396_Human | 0.82009036 |
111 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.81892455 |
112 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.81806541 |
113 | SA1_27219007_Chip-Seq_Bcells_Human | 0.81372176 |
114 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.80816028 |
115 | NFYB_21822215_ChIP-Seq_K562_Human | 0.79969124 |
116 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.79739281 |
117 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.79698212 |
118 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.79330013 |
119 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.78984798 |
120 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.78737311 |
121 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.78205135 |
122 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.77885815 |
123 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.77684422 |
124 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.77430643 |
125 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.76229185 |
126 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.74266780 |
127 | * LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.73946891 |
128 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.73754886 |
129 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73706583 |
130 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.71762813 |
131 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.70970905 |
132 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.70740327 |
133 | CBP_21632823_ChIP-Seq_H3396_Human | 0.70582604 |
134 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.69660494 |
135 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.69042688 |
136 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.68736043 |
137 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.68615077 |
138 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.66022983 |
139 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.65863142 |
140 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.65863142 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005083_abnormal_biliary_tract | 9.37158145 |
2 | * MP0001666_abnormal_nutrient_absorption | 7.64285141 |
3 | MP0005220_abnormal_exocrine_pancreas | 6.40147987 |
4 | MP0005365_abnormal_bile_salt | 6.23484555 |
5 | MP0003868_abnormal_feces_composition | 5.21849702 |
6 | MP0005084_abnormal_gallbladder_morpholo | 4.78933748 |
7 | MP0005085_abnormal_gallbladder_physiolo | 3.38897418 |
8 | MP0002693_abnormal_pancreas_physiology | 3.21047759 |
9 | MP0002138_abnormal_hepatobiliary_system | 2.71308991 |
10 | MP0001944_abnormal_pancreas_morphology | 2.41885132 |
11 | MP0001664_abnormal_digestion | 2.38485301 |
12 | MP0004264_abnormal_extraembryonic_tissu | 2.30802539 |
13 | MP0000627_abnormal_mammary_gland | 2.24331665 |
14 | MP0002139_abnormal_hepatobiliary_system | 2.20181325 |
15 | MP0003705_abnormal_hypodermis_morpholog | 2.18815311 |
16 | MP0010234_abnormal_vibrissa_follicle | 2.13245120 |
17 | MP0003252_abnormal_bile_duct | 1.84593735 |
18 | MP0002928_abnormal_bile_duct | 1.67548125 |
19 | MP0003283_abnormal_digestive_organ | 1.62562643 |
20 | * MP0003959_abnormal_lean_body | 1.62233145 |
21 | MP0003300_gastrointestinal_ulcer | 1.49677637 |
22 | MP0003718_maternal_effect | 1.42559325 |
23 | MP0004233_abnormal_muscle_weight | 1.35827702 |
24 | MP0008004_abnormal_stomach_pH | 1.25099323 |
25 | MP0003638_abnormal_response/metabolism_ | 1.22582707 |
26 | * MP0002118_abnormal_lipid_homeostasis | 1.22444988 |
27 | MP0006054_spinal_hemorrhage | 1.20761833 |
28 | * MP0002078_abnormal_glucose_homeostasis | 1.19131031 |
29 | MP0009780_abnormal_chondrocyte_physiolo | 1.18243766 |
30 | MP0000003_abnormal_adipose_tissue | 1.17515121 |
31 | MP0005165_increased_susceptibility_to | 1.17118059 |
32 | * MP0005448_abnormal_energy_balance | 1.14033348 |
33 | MP0003045_fibrosis | 1.12937227 |
34 | MP0004019_abnormal_vitamin_homeostasis | 1.06449352 |
35 | MP0002132_abnormal_respiratory_system | 1.05170750 |
36 | MP0005332_abnormal_amino_acid | 1.04759258 |
37 | MP0000470_abnormal_stomach_morphology | 1.02012966 |
38 | MP0008961_abnormal_basal_metabolism | 1.01046123 |
39 | MP0010352_gastrointestinal_tract_polyps | 1.00729100 |
40 | MP0002277_abnormal_respiratory_mucosa | 0.98555767 |
41 | MP0002877_abnormal_melanocyte_morpholog | 0.93120457 |
42 | MP0001849_ear_inflammation | 0.92852505 |
43 | MP0009643_abnormal_urine_homeostasis | 0.91374605 |
44 | MP0001881_abnormal_mammary_gland | 0.90378842 |
45 | MP0008438_abnormal_cutaneous_collagen | 0.89326719 |
46 | MP0005408_hypopigmentation | 0.87650188 |
47 | MP0001873_stomach_inflammation | 0.86046486 |
48 | MP0000613_abnormal_salivary_gland | 0.83992754 |
49 | MP0005535_abnormal_body_temperature | 0.82958889 |
50 | MP0002163_abnormal_gland_morphology | 0.82921908 |
51 | MP0009384_cardiac_valve_regurgitation | 0.82839129 |
52 | MP0003566_abnormal_cell_adhesion | 0.81345672 |
53 | MP0002970_abnormal_white_adipose | 0.80359644 |
54 | MP0005395_other_phenotype | 0.78724707 |
55 | * MP0003953_abnormal_hormone_level | 0.78374730 |
56 | MP0002896_abnormal_bone_mineralization | 0.74317135 |
57 | MP0000490_abnormal_crypts_of | 0.70650399 |
58 | MP0001502_abnormal_circadian_rhythm | 0.70455135 |
59 | MP0005058_abnormal_lysosome_morphology | 0.69204093 |
60 | MP0004043_abnormal_pH_regulation | 0.66902400 |
61 | MP0005375_adipose_tissue_phenotype | 0.66625498 |
62 | MP0003866_abnormal_defecation | 0.65396484 |
63 | MP0010329_abnormal_lipoprotein_level | 0.65201250 |
64 | MP0000013_abnormal_adipose_tissue | 0.64559825 |
65 | MP0004185_abnormal_adipocyte_glucose | 0.63924498 |
66 | MP0003195_calcinosis | 0.62719628 |
67 | MP0005451_abnormal_body_composition | 0.61420238 |
68 | MP0003879_abnormal_hair_cell | 0.61356408 |
69 | MP0005636_abnormal_mineral_homeostasis | 0.58714005 |
70 | MP0002254_reproductive_system_inflammat | 0.58564921 |
71 | MP0003183_abnormal_peptide_metabolism | 0.58137379 |
72 | MP0005410_abnormal_fertilization | 0.57772751 |
73 | MP0003936_abnormal_reproductive_system | 0.56077004 |
74 | MP0000609_abnormal_liver_physiology | 0.55269433 |
75 | MP0008789_abnormal_olfactory_epithelium | 0.54126158 |
76 | MP0010386_abnormal_urinary_bladder | 0.53384364 |
77 | MP0002098_abnormal_vibrissa_morphology | 0.53219005 |
78 | MP0003011_delayed_dark_adaptation | 0.52169609 |
79 | MP0000858_altered_metastatic_potential | 0.52127692 |
80 | MP0001663_abnormal_digestive_system | 0.52032256 |
81 | MP0003091_abnormal_cell_migration | 0.51827882 |
82 | MP0001731_abnormal_postnatal_growth | 0.50429885 |
83 | MP0004272_abnormal_basement_membrane | 0.50081432 |
84 | MP0002909_abnormal_adrenal_gland | 0.49553131 |
85 | MP0005381_digestive/alimentary_phenotyp | 0.49184141 |
86 | MP0008770_decreased_survivor_rate | 0.49120965 |
87 | MP0009703_decreased_birth_body | 0.47153407 |
88 | * MP0005452_abnormal_adipose_tissue | 0.46817885 |
89 | MP0005645_abnormal_hypothalamus_physiol | 0.46591180 |
90 | MP0002796_impaired_skin_barrier | 0.46248710 |
91 | MP0005409_darkened_coat_color | 0.45774897 |
92 | MP0005187_abnormal_penis_morphology | 0.45446967 |
93 | MP0005334_abnormal_fat_pad | 0.45432739 |
94 | MP0003122_maternal_imprinting | 0.45114064 |
95 | MP0003943_abnormal_hepatobiliary_system | 0.44846798 |
96 | MP0003329_amyloid_beta_deposits | 0.44659714 |
97 | * MP0000598_abnormal_liver_morphology | 0.43379366 |
98 | MP0005377_hearing/vestibular/ear_phenot | 0.42878568 |
99 | MP0003878_abnormal_ear_physiology | 0.42878568 |
100 | MP0003453_abnormal_keratinocyte_physiol | 0.42671997 |
101 | MP0003795_abnormal_bone_structure | 0.42250746 |
102 | MP0002060_abnormal_skin_morphology | 0.41719622 |
103 | MP0002234_abnormal_pharynx_morphology | 0.40731091 |
104 | MP0000377_abnormal_hair_follicle | 0.39655781 |
105 | MP0005394_taste/olfaction_phenotype | 0.38517854 |
106 | MP0005499_abnormal_olfactory_system | 0.38517854 |
107 | MP0001765_abnormal_ion_homeostasis | 0.37611532 |
108 | MP0009672_abnormal_birth_weight | 0.37324904 |
109 | MP0003950_abnormal_plasma_membrane | 0.37171444 |
110 | MP0004130_abnormal_muscle_cell | 0.36860559 |
111 | MP0003806_abnormal_nucleotide_metabolis | 0.36788940 |
112 | MP0001727_abnormal_embryo_implantation | 0.36593338 |
113 | MP0010678_abnormal_skin_adnexa | 0.36514091 |
114 | MP0001845_abnormal_inflammatory_respons | 0.36226901 |
115 | MP0000678_abnormal_parathyroid_gland | 0.36191968 |
116 | MP0005379_endocrine/exocrine_gland_phen | 0.35814130 |
117 | MP0009642_abnormal_blood_homeostasis | 0.34671241 |
118 | MP0009840_abnormal_foam_cell | 0.34549834 |
119 | MP0002089_abnormal_postnatal_growth/wei | 0.34246617 |
120 | MP0002168_other_aberrant_phenotype | 0.33939355 |
121 | MP0002069_abnormal_eating/drinking_beha | 0.33831875 |
122 | MP0009765_abnormal_xenobiotic_induced | 0.33735466 |
123 | MP0001501_abnormal_sleep_pattern | 0.33611716 |
124 | MP0006036_abnormal_mitochondrial_physio | 0.33459722 |
125 | MP0002876_abnormal_thyroid_physiology | 0.33200672 |
126 | MP0000371_diluted_coat_color | 0.33092451 |
127 | MP0000367_abnormal_coat/_hair | 0.32686841 |
128 | MP0005319_abnormal_enzyme/_coenzyme | 0.32671150 |
129 | MP0000462_abnormal_digestive_system | 0.31832084 |
130 | MP0003119_abnormal_digestive_system | 0.31775625 |
131 | MP0001756_abnormal_urination | 0.31644944 |
132 | MP0003172_abnormal_lysosome_physiology | 0.31231400 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Steatorrhea (HP:0002570) | 7.59831206 |
2 | Gout (HP:0001997) | 6.57349367 |
3 | Fat malabsorption (HP:0002630) | 6.53400758 |
4 | Exocrine pancreatic insufficiency (HP:0001738) | 5.20285291 |
5 | Abnormal pancreas size (HP:0012094) | 5.00959063 |
6 | Decreased subcutaneous fat (HP:0001002) | 4.70489264 |
7 | Abnormality of the pancreatic islet cells (HP:0006476) | 4.54012172 |
8 | Abnormality of endocrine pancreas physiology (HP:0012093) | 4.54012172 |
9 | Abnormality of the intrinsic pathway (HP:0010989) | 4.41157461 |
10 | Short chin (HP:0000331) | 4.39475341 |
11 | Ketoacidosis (HP:0001993) | 4.32352368 |
12 | Abnormality of subcutaneous fat tissue (HP:0001001) | 4.27754733 |
13 | Nephritis (HP:0000123) | 4.17231654 |
14 | Type I diabetes mellitus (HP:0100651) | 4.17146076 |
15 | Hyperinsulinemic hypoglycemia (HP:0000825) | 4.04857237 |
16 | Hypoglycemic seizures (HP:0002173) | 3.92872855 |
17 | Hypoglycemic coma (HP:0001325) | 3.89916719 |
18 | Hypoplasia of the pons (HP:0012110) | 3.87793612 |
19 | Ketosis (HP:0001946) | 3.71134032 |
20 | Tubulointerstitial fibrosis (HP:0005576) | 3.70144099 |
21 | Thin bony cortex (HP:0002753) | 3.61226876 |
22 | Abnormality of the pons (HP:0007361) | 3.57448387 |
23 | Maternal diabetes (HP:0009800) | 3.55229122 |
24 | Pancreatitis (HP:0001733) | 3.45291869 |
25 | Tubulointerstitial nephritis (HP:0001970) | 3.38618390 |
26 | Late onset (HP:0003584) | 3.38067348 |
27 | Abnormality of the pleura (HP:0002103) | 3.37130362 |
28 | Hyperactive renin-angiotensin system (HP:0000841) | 3.24261600 |
29 | Premature skin wrinkling (HP:0100678) | 3.23209927 |
30 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.17322258 |
31 | Hypoproteinemia (HP:0003075) | 3.16783156 |
32 | Symptomatic seizures (HP:0011145) | 3.13042188 |
33 | Hyperglycemia (HP:0003074) | 3.06327274 |
34 | Cortical dysplasia (HP:0002539) | 3.04497480 |
35 | Male infertility (HP:0003251) | 3.01820940 |
36 | Abnormality of nucleobase metabolism (HP:0010932) | 3.01017629 |
37 | Decreased circulating renin level (HP:0003351) | 2.90659943 |
38 | Increased purine levels (HP:0004368) | 2.90484580 |
39 | Hyperuricemia (HP:0002149) | 2.90484580 |
40 | Joint stiffness (HP:0001387) | 2.88537277 |
41 | Ileus (HP:0002595) | 2.87366655 |
42 | Abnormality of chloride homeostasis (HP:0011422) | 2.87033562 |
43 | Abnormality of the common coagulation pathway (HP:0010990) | 2.85493725 |
44 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.73770387 |
45 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.65688981 |
46 | Large for gestational age (HP:0001520) | 2.65639776 |
47 | Abnormality of purine metabolism (HP:0004352) | 2.64412389 |
48 | Carpal bone hypoplasia (HP:0001498) | 2.61749240 |
49 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.60904506 |
50 | Congenital glaucoma (HP:0001087) | 2.58549060 |
51 | Esophageal varix (HP:0002040) | 2.44422091 |
52 | Ventricular fibrillation (HP:0001663) | 2.40904884 |
53 | Hyperglycinemia (HP:0002154) | 2.36083168 |
54 | Long foot (HP:0001833) | 2.34848493 |
55 | Abnormal tarsal ossification (HP:0008369) | 2.32851898 |
56 | Dysostosis multiplex (HP:0000943) | 2.30042660 |
57 | Fatigue (HP:0012378) | 2.29896964 |
58 | Facial shape deformation (HP:0011334) | 2.29541018 |
59 | Potter facies (HP:0002009) | 2.29541018 |
60 | Tetraparesis (HP:0002273) | 2.27943129 |
61 | Abnormality of the renal cortex (HP:0011035) | 2.26983882 |
62 | Conjugated hyperbilirubinemia (HP:0002908) | 2.26774363 |
63 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.26247107 |
64 | Deformed sella turcica (HP:0002681) | 2.25184167 |
65 | Malnutrition (HP:0004395) | 2.21014740 |
66 | Hypoplasia of the odontoid process (HP:0003311) | 2.19708535 |
67 | Right ventricular cardiomyopathy (HP:0011663) | 2.18535011 |
68 | Unilateral renal agenesis (HP:0000122) | 2.16805779 |
69 | Villous atrophy (HP:0011473) | 2.16184036 |
70 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.16184036 |
71 | Vascular calcification (HP:0004934) | 2.15129657 |
72 | Ankyloglossia (HP:0010296) | 2.14939742 |
73 | Cortical visual impairment (HP:0100704) | 2.14542205 |
74 | Severe short stature (HP:0003510) | 2.14392058 |
75 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.13402700 |
76 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.13402700 |
77 | Abnormal protein glycosylation (HP:0012346) | 2.13402700 |
78 | Abnormal glycosylation (HP:0012345) | 2.13402700 |
79 | Pectus carinatum (HP:0000768) | 2.12301719 |
80 | Flat acetabular roof (HP:0003180) | 2.10599710 |
81 | Tubular atrophy (HP:0000092) | 2.10577806 |
82 | Progressive muscle weakness (HP:0003323) | 2.10278069 |
83 | Insulin resistance (HP:0000855) | 2.10239182 |
84 | Tubulointerstitial abnormality (HP:0001969) | 2.08514477 |
85 | Hyperglycinuria (HP:0003108) | 2.05910095 |
86 | Acute hepatic failure (HP:0006554) | 2.04953486 |
87 | Enlarged penis (HP:0000040) | 2.02845968 |
88 | Anal atresia (HP:0002023) | 2.02206805 |
89 | Hypotension (HP:0002615) | 2.02084589 |
90 | Neoplasm of the heart (HP:0100544) | 2.01966724 |
91 | Hydroxyprolinuria (HP:0003080) | 2.01256630 |
92 | Abnormality of proline metabolism (HP:0010907) | 2.01256630 |
93 | Hyperphosphatemia (HP:0002905) | 2.00689028 |
94 | Small epiphyses (HP:0010585) | 2.00229585 |
95 | Prenatal maternal abnormality (HP:0002686) | 1.95587505 |
96 | Hypsarrhythmia (HP:0002521) | 1.95507132 |
97 | Mucopolysacchariduria (HP:0008155) | 1.95168173 |
98 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.95168173 |
99 | Abnormality of renin-angiotensin system (HP:0000847) | 1.93602634 |
100 | Limb hypertonia (HP:0002509) | 1.93032964 |
101 | Type II lissencephaly (HP:0007260) | 1.92236915 |
102 | Broad metatarsal (HP:0001783) | 1.90886399 |
103 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.90703174 |
104 | Prolonged QT interval (HP:0001657) | 1.89953462 |
105 | Abdominal distention (HP:0003270) | 1.88452564 |
106 | Neonatal death (HP:0003811) | 1.87688744 |
107 | Epiphyseal dysplasia (HP:0002656) | 1.87666882 |
108 | Vacuolated lymphocytes (HP:0001922) | 1.86958695 |
109 | EEG with generalized epileptiform discharges (HP:0011198) | 1.86097114 |
110 | Epidermoid cyst (HP:0200040) | 1.86038926 |
111 | Renal salt wasting (HP:0000127) | 1.84270309 |
112 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.83714373 |
113 | Abnormality of glycine metabolism (HP:0010895) | 1.83714373 |
114 | Cardiovascular calcification (HP:0011915) | 1.82612999 |
115 | Hyperkalemia (HP:0002153) | 1.82083856 |
116 | Azoospermia (HP:0000027) | 1.81806921 |
117 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.81563765 |
118 | Abnormal foot bone ossification (HP:0010675) | 1.81317667 |
119 | Axonal loss (HP:0003447) | 1.81216582 |
120 | Glomerulosclerosis (HP:0000096) | 1.80568627 |
121 | Hyperlipoproteinemia (HP:0010980) | 1.80383397 |
122 | Barrel-shaped chest (HP:0001552) | 1.80036826 |
123 | Myocardial infarction (HP:0001658) | 1.79427071 |
124 | Hyperaldosteronism (HP:0000859) | 1.78859684 |
125 | Intrahepatic cholestasis (HP:0001406) | 1.78001669 |
126 | Rectal prolapse (HP:0002035) | 1.77549480 |
127 | Skin nodule (HP:0200036) | 1.77453384 |
128 | Glucose intolerance (HP:0000833) | 1.76075935 |
129 | Epileptiform EEG discharges (HP:0011182) | 1.75441158 |
130 | Optic nerve hypoplasia (HP:0000609) | 1.72498634 |
131 | Abnormality of the odontoid process (HP:0003310) | 1.72220940 |
132 | Absent eyelashes (HP:0000561) | 1.71730134 |
133 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.71294525 |
134 | Hypoplasia of dental enamel (HP:0006297) | 1.71218998 |
135 | J-shaped sella turcica (HP:0002680) | 1.68651262 |
136 | Xanthomatosis (HP:0000991) | 1.66897726 |
137 | Popliteal pterygium (HP:0009756) | 1.66186744 |
138 | Germ cell neoplasia (HP:0100728) | 1.57149435 |
139 | Dehydration (HP:0001944) | 1.54155970 |
140 | Thoracic kyphosis (HP:0002942) | 1.52993697 |
141 | Abnormality of the right ventricle (HP:0001707) | 1.52854049 |
142 | Nephrolithiasis (HP:0000787) | 1.52553087 |
143 | Abnormal biliary tract morphology (HP:0012440) | 1.50027834 |
144 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.49427749 |
145 | Abdominal pain (HP:0002027) | 1.49160941 |
146 | Hypercalciuria (HP:0002150) | 1.49055071 |
147 | Abnormality of the sella turcica (HP:0002679) | 1.47934952 |
148 | Elevated alkaline phosphatase (HP:0003155) | 1.46179682 |
149 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.46040160 |
150 | Abnormality of the costochondral junction (HP:0000919) | 1.45487503 |
151 | Spinal canal stenosis (HP:0003416) | 1.42680396 |
152 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.41885684 |
153 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.39654336 |
154 | Bronchomalacia (HP:0002780) | 1.39534007 |
155 | Protuberant abdomen (HP:0001538) | 1.37039026 |
156 | Lymphangioma (HP:0100764) | 1.33673139 |
157 | Abnormality of the nasal septum (HP:0000419) | 1.33540279 |
158 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.33226394 |
159 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.33226394 |
160 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.33226394 |
Rank | Gene Set | Z-score |
---|---|---|
1 | LMTK2 | 8.65177032 |
2 | BCKDK | 7.67148972 |
3 | ERN1 | 4.75042788 |
4 | EPHA2 | 4.08405936 |
5 | EIF2AK3 | 3.92097813 |
6 | TRIB3 | 3.90958471 |
7 | INSRR | 3.84230779 |
8 | PKN2 | 3.52057196 |
9 | MAP2K2 | 3.46579248 |
10 | FRK | 2.91551745 |
11 | TAOK3 | 2.71983376 |
12 | IRAK3 | 1.88348635 |
13 | MAPK15 | 1.85265849 |
14 | ZAP70 | 1.84222277 |
15 | SIK1 | 1.79113997 |
16 | MAPKAPK3 | 1.78980239 |
17 | PTK6 | 1.78652753 |
18 | SCYL2 | 1.70794241 |
19 | PRKG2 | 1.66787656 |
20 | LATS1 | 1.56393214 |
21 | WNK4 | 1.51985649 |
22 | MAP3K2 | 1.49637121 |
23 | ICK | 1.46388084 |
24 | FLT3 | 1.41212601 |
25 | PDGFRB | 1.40135390 |
26 | EEF2K | 1.38797116 |
27 | NLK | 1.37882451 |
28 | MAP2K1 | 1.36996698 |
29 | PAK2 | 1.32080864 |
30 | PASK | 1.21531839 |
31 | TRPM7 | 1.16158339 |
32 | STK38 | 1.04488689 |
33 | RPS6KB2 | 1.03089423 |
34 | RIPK1 | 1.02989858 |
35 | PRKD3 | 1.02969299 |
36 | MARK2 | 0.99163553 |
37 | NME2 | 0.97412728 |
38 | PDGFRA | 0.97400452 |
39 | SGK3 | 0.97035676 |
40 | RET | 0.96876006 |
41 | DYRK1A | 0.96230294 |
42 | CAMK1D | 0.93618442 |
43 | CAMKK1 | 0.93297881 |
44 | MAP3K9 | 0.92261984 |
45 | PIK3CA | 0.91846015 |
46 | HIPK2 | 0.88834825 |
47 | MAP3K1 | 0.85307685 |
48 | MTOR | 0.83003945 |
49 | DYRK1B | 0.82014437 |
50 | NME1 | 0.81739988 |
51 | PIK3CG | 0.76807130 |
52 | PRKCH | 0.75373154 |
53 | MAP3K6 | 0.73629048 |
54 | CDK12 | 0.72208587 |
55 | TESK1 | 0.71999861 |
56 | PTK2 | 0.69992972 |
57 | EPHA3 | 0.69701635 |
58 | IRAK2 | 0.69331428 |
59 | DAPK2 | 0.68889261 |
60 | FER | 0.68667433 |
61 | SGK2 | 0.68296454 |
62 | CAMKK2 | 0.68216715 |
63 | BMX | 0.68062249 |
64 | FGFR4 | 0.65598284 |
65 | CHUK | 0.63962995 |
66 | CAMK1G | 0.63711167 |
67 | EPHB1 | 0.62565701 |
68 | LRRK2 | 0.61903827 |
69 | PDK2 | 0.61289386 |
70 | NTRK1 | 0.60860075 |
71 | MET | 0.60687957 |
72 | SGK223 | 0.60027902 |
73 | SGK494 | 0.60027902 |
74 | MELK | 0.58062602 |
75 | RPS6KA2 | 0.56966987 |
76 | STK24 | 0.56639123 |
77 | PRKCI | 0.53210903 |
78 | GRK1 | 0.51964504 |
79 | JAK2 | 0.51102458 |
80 | ROCK1 | 0.50869959 |
81 | RPS6KB1 | 0.49118596 |
82 | PDPK1 | 0.49077756 |
83 | STK39 | 0.46956439 |
84 | STK38L | 0.46527031 |
85 | STK16 | 0.45736691 |
86 | IRAK1 | 0.45566089 |
87 | MAP3K7 | 0.44608545 |
88 | PRKCZ | 0.43896604 |
89 | ERBB2 | 0.43496647 |
90 | PRKD1 | 0.43207505 |
91 | KSR2 | 0.41137059 |
92 | MAP2K6 | 0.37835088 |
93 | PDK1 | 0.35933825 |
94 | IRAK4 | 0.35635446 |
95 | FGFR3 | 0.34383572 |
96 | PAK4 | 0.34119931 |
97 | PRKD2 | 0.32518340 |
98 | GSK3A | 0.32213709 |
99 | IGF1R | 0.32050921 |
100 | TAOK1 | 0.32030472 |
101 | PRPF4B | 0.31825702 |
102 | MAP3K3 | 0.29892391 |
103 | PRKAA1 | 0.29430450 |
104 | MUSK | 0.28996579 |
105 | MAP3K5 | 0.28969874 |
106 | DDR2 | 0.28294465 |
107 | MAP3K13 | 0.27846477 |
108 | NEK6 | 0.26333674 |
109 | MAPK3 | 0.26241698 |
110 | TGFBR2 | 0.26065452 |
111 | PDK4 | 0.25722576 |
112 | PDK3 | 0.25722576 |
113 | CDC42BPA | 0.25367586 |
114 | WNK1 | 0.24039812 |
115 | ILK | 0.23401222 |
116 | MAPK12 | 0.23338826 |
117 | KSR1 | 0.23190040 |
118 | JAK1 | 0.21843013 |
119 | PRKAA2 | 0.21646976 |
120 | RPS6KA1 | 0.19911840 |
121 | IKBKE | 0.19608818 |
122 | JAK3 | 0.19036220 |
123 | CDK9 | 0.18839144 |
124 | MAPK1 | 0.18778414 |
125 | PRKCE | 0.18572408 |
126 | ABL1 | 0.18369882 |
127 | PRKACB | 0.17731086 |
128 | CSNK1A1 | 0.17404048 |
129 | NTRK3 | 0.16987062 |
130 | MAP3K14 | 0.16734842 |
131 | UHMK1 | 0.16687929 |
132 | MAP3K12 | 0.16480690 |
133 | MAP3K10 | 0.15771464 |
134 | AKT1 | 0.14743619 |
135 | EGFR | 0.14635417 |
136 | SRC | 0.14225706 |
137 | MST1R | 0.13853076 |
138 | TBK1 | 0.12648747 |
139 | CSNK1E | 0.12425986 |
140 | NUAK1 | 0.11194734 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Pancreatic secretion_Homo sapiens_hsa04972 | 8.12653062 |
2 | Protein digestion and absorption_Homo sapiens_hsa04974 | 5.79250301 |
3 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 5.01790493 |
4 | * Fat digestion and absorption_Homo sapiens_hsa04975 | 4.95769982 |
5 | Protein export_Homo sapiens_hsa03060 | 3.68870915 |
6 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.76900844 |
7 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.51474037 |
8 | * Glycerolipid metabolism_Homo sapiens_hsa00561 | 2.05802619 |
9 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.99782120 |
10 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.94614358 |
11 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.90715241 |
12 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.88516992 |
13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.60607373 |
14 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.45636330 |
15 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.36728481 |
16 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.30722141 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 1.26740362 |
18 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.14429927 |
19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.09315166 |
20 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.02986943 |
21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.99101908 |
22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.93790746 |
23 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.92569469 |
24 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.89693099 |
25 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.89388255 |
26 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.83809629 |
27 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.83388580 |
28 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.77804238 |
29 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.76585451 |
30 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.73693827 |
31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.72763828 |
32 | Histidine metabolism_Homo sapiens_hsa00340 | 0.72066159 |
33 | Other glycan degradation_Homo sapiens_hsa00511 | 0.71831151 |
34 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.71306432 |
35 | Influenza A_Homo sapiens_hsa05164 | 0.70348739 |
36 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.66908390 |
37 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65812631 |
38 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.65530391 |
39 | Circadian rhythm_Homo sapiens_hsa04710 | 0.65090446 |
40 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.65054509 |
41 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.58741740 |
42 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.53169316 |
43 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.51337683 |
44 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.51050415 |
45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.50047757 |
46 | Galactose metabolism_Homo sapiens_hsa00052 | 0.47529028 |
47 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.47450448 |
48 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.46315375 |
49 | Insulin resistance_Homo sapiens_hsa04931 | 0.46218319 |
50 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.45754762 |
51 | Lysosome_Homo sapiens_hsa04142 | 0.45740884 |
52 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.45554519 |
53 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.42626722 |
54 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42372778 |
55 | Endometrial cancer_Homo sapiens_hsa05213 | 0.41942834 |
56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.41404129 |
57 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.41358881 |
58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.39944904 |
59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.39571910 |
60 | Legionellosis_Homo sapiens_hsa05134 | 0.38988932 |
61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.38669256 |
62 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38003746 |
63 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.35417003 |
64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.33761015 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.30884082 |
66 | Peroxisome_Homo sapiens_hsa04146 | 0.30123482 |
67 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29004869 |
68 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.28950698 |
69 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.27743886 |
70 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.27380256 |
71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.27103251 |
72 | Cocaine addiction_Homo sapiens_hsa05030 | 0.26006962 |
73 | Prostate cancer_Homo sapiens_hsa05215 | 0.25674513 |
74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.25304777 |
75 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.24416006 |
76 | Hepatitis C_Homo sapiens_hsa05160 | 0.23883821 |
77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.23670360 |
78 | Tight junction_Homo sapiens_hsa04530 | 0.23132825 |
79 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.23024678 |
80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22314072 |
81 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.21628997 |
82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.21307231 |
83 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.20987162 |
84 | ABC transporters_Homo sapiens_hsa02010 | 0.20892021 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.20597745 |
86 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.20368283 |
87 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.20129865 |
88 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.19363639 |
89 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.19188500 |
90 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.18619394 |
91 | Bladder cancer_Homo sapiens_hsa05219 | 0.18351884 |
92 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.18343402 |
93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.17439941 |
94 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.17340129 |
95 | Adherens junction_Homo sapiens_hsa04520 | 0.17327790 |
96 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.17307054 |
97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.16695911 |
98 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.16321784 |
99 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.16214345 |
100 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.16059499 |
101 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.15852435 |
102 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.15061750 |
103 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.14912398 |
104 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.13593967 |
105 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.13404376 |
106 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.13074194 |
107 | Carbon metabolism_Homo sapiens_hsa01200 | 0.12733028 |
108 | Lysine degradation_Homo sapiens_hsa00310 | 0.12428801 |
109 | Bile secretion_Homo sapiens_hsa04976 | 0.10980334 |
110 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.09651091 |
111 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.09540343 |
112 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.08971661 |
113 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.08815361 |
114 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.07743943 |
115 | Sulfur relay system_Homo sapiens_hsa04122 | 0.07636291 |
116 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.06865008 |
117 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.06618128 |
118 | Thyroid cancer_Homo sapiens_hsa05216 | 0.06364764 |
119 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.06178338 |
120 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.05219542 |
121 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.04143455 |
122 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.03790489 |
123 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.00024620 |
124 | FoxO signaling pathway_Homo sapiens_hsa04068 | -0.0350427 |
125 | Butanoate metabolism_Homo sapiens_hsa00650 | -0.0343149 |
126 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.0322013 |
127 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | -0.0260062 |
128 | Endocytosis_Homo sapiens_hsa04144 | -0.0241121 |
129 | Complement and coagulation cascades_Homo sapiens_hsa04610 | -0.0099321 |
130 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | -0.0006234 |
131 | GnRH signaling pathway_Homo sapiens_hsa04912 | -0.0005736 |