CEMP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of T cell apoptotic process (GO:0070234)5.58501945
2response to xenobiotic stimulus (GO:0009410)5.57601589
3N-acetylneuraminate metabolic process (GO:0006054)5.43946063
4positive regulation of lymphocyte apoptotic process (GO:0070230)5.18793981
5amino sugar catabolic process (GO:0046348)4.93507187
6superoxide anion generation (GO:0042554)4.76240802
7L-ascorbic acid metabolic process (GO:0019852)4.36062749
8response to acidic pH (GO:0010447)4.18575910
9positive regulation of mast cell activation involved in immune response (GO:0033008)4.11188855
10positive regulation of mast cell degranulation (GO:0043306)4.11188855
11negative regulation of interleukin-12 production (GO:0032695)4.04207837
12polyamine biosynthetic process (GO:0006596)3.88851112
13fusion of sperm to egg plasma membrane (GO:0007342)3.84565651
14folic acid transport (GO:0015884)3.76986632
15positive regulation of mast cell activation (GO:0033005)3.76811057
16negative regulation of T cell differentiation in thymus (GO:0033085)3.70970346
17peptidyl-proline hydroxylation (GO:0019511)3.69766499
18positive regulation by symbiont of host defense response (GO:0052509)3.69333067
19modulation by symbiont of host defense response (GO:0052031)3.69333067
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.69333067
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.69333067
22positive regulation by organism of defense response of other organism involved in symbiotic interact3.69333067
23modulation by symbiont of host immune response (GO:0052553)3.69333067
24iron coordination entity transport (GO:1901678)3.61845084
25cysteine metabolic process (GO:0006534)3.54761914
26glycosphingolipid catabolic process (GO:0046479)3.52263852
27viral transcription (GO:0019083)3.51045488
28negative regulation of granulocyte differentiation (GO:0030853)3.50409094
29homocysteine metabolic process (GO:0050667)3.48777970
30adenosine receptor signaling pathway (GO:0001973)3.44313741
31ncRNA 3-end processing (GO:0043628)3.40574135
32regulation of mast cell degranulation (GO:0043304)3.39134534
33cardiovascular system development (GO:0072358)3.35800975
34negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.34162029
35N-acetylglucosamine metabolic process (GO:0006044)3.33697805
36negative regulation of cell cycle G2/M phase transition (GO:1902750)3.30575817
37adhesion of symbiont to host cell (GO:0044650)3.27333565
38virion attachment to host cell (GO:0019062)3.27333565
39barbed-end actin filament capping (GO:0051016)3.14128843
40positive regulation of leukocyte degranulation (GO:0043302)3.10986976
41phagosome maturation (GO:0090382)3.10781744
42pentose metabolic process (GO:0019321)3.09206636
43NIK/NF-kappaB signaling (GO:0038061)3.09172695
44plasma membrane fusion (GO:0045026)3.09160143
45sperm motility (GO:0030317)3.07784346
46glycolipid catabolic process (GO:0019377)3.05721865
47hydrogen peroxide biosynthetic process (GO:0050665)3.02737930
48macrophage activation involved in immune response (GO:0002281)3.02618757
49G-protein coupled receptor internalization (GO:0002031)3.02251479
50ribosomal small subunit assembly (GO:0000028)3.00822794
51regulation of early endosome to late endosome transport (GO:2000641)2.98876919
52translational termination (GO:0006415)2.98449308
53cell-cell junction maintenance (GO:0045217)2.98087799
54positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.97267283
55negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.96314413
56negative regulation of cell killing (GO:0031342)2.96314413
57regulation of superoxide anion generation (GO:0032928)2.95874466
58regulation of mast cell activation involved in immune response (GO:0033006)2.91023722
59cellular response to pH (GO:0071467)2.90633966
60oligosaccharide catabolic process (GO:0009313)2.90146020
61positive regulation of leukocyte apoptotic process (GO:2000108)2.89793043
62positive regulation of chemokine biosynthetic process (GO:0045080)2.88895216
63activation of MAPKKK activity (GO:0000185)2.88365689
64response to pH (GO:0009268)2.87561707
65ceramide catabolic process (GO:0046514)2.86119271
664-hydroxyproline metabolic process (GO:0019471)2.84768218
67cellular response to arsenic-containing substance (GO:0071243)2.81522515
68arginine catabolic process (GO:0006527)2.80966730
69negative regulation of tumor necrosis factor production (GO:0032720)2.79101997
70response to peptidoglycan (GO:0032494)2.78142608
71adhesion of symbiont to host (GO:0044406)2.76053217
72negative regulation of myeloid cell apoptotic process (GO:0033033)2.75730935
73ribosomal small subunit biogenesis (GO:0042274)2.73229671
74positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.72637063
75single strand break repair (GO:0000012)2.72082946
76viral life cycle (GO:0019058)2.69853158
77negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.68046042
78peptide catabolic process (GO:0043171)2.66085876
79negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)2.65785313
80immunoglobulin mediated immune response (GO:0016064)2.65453463
81glutathione biosynthetic process (GO:0006750)2.65040518
82nonribosomal peptide biosynthetic process (GO:0019184)2.64920274
83negative regulation of interleukin-1 beta production (GO:0032691)2.63793447
84chaperone-mediated protein transport (GO:0072321)2.63237090
85antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.62790814
86polyamine metabolic process (GO:0006595)2.62271621
87acrosome reaction (GO:0007340)2.62193750
88cellular response to thyroid hormone stimulus (GO:0097067)2.62112932
89regulation of chemokine biosynthetic process (GO:0045073)2.61258751
90regulation of interferon-gamma biosynthetic process (GO:0045072)2.60813131
91translational elongation (GO:0006414)2.60764381
92protein polyglutamylation (GO:0018095)2.60306330
93superoxide metabolic process (GO:0006801)2.59146202
94positive regulation of receptor recycling (GO:0001921)2.58881775
95positive regulation of regulated secretory pathway (GO:1903307)2.58712102
96negative regulation of interleukin-1 production (GO:0032692)2.58619962
97neutrophil activation involved in immune response (GO:0002283)2.57954882
98positive regulation of DNA biosynthetic process (GO:2000573)2.57295418
99chromatin silencing (GO:0006342)2.54199447
100positive regulation of smooth muscle cell migration (GO:0014911)2.52644916

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.21328132
2LXR_22292898_ChIP-Seq_THP-1_Human2.82264405
3VDR_21846776_ChIP-Seq_THP-1_Human2.80123054
4THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.44813773
5BCL6_27268052_Chip-Seq_Bcells_Human2.20847999
6NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.16867902
7IKZF1_21737484_ChIP-ChIP_HCT116_Human2.13937278
8P68_20966046_ChIP-Seq_HELA_Human2.13552690
9ELF1_20517297_ChIP-Seq_JURKAT_Human2.10575126
10SRY_22984422_ChIP-ChIP_TESTIS_Rat2.05588695
11ERG_21242973_ChIP-ChIP_JURKAT_Human1.91843459
12TET1_21451524_ChIP-Seq_MESCs_Mouse1.90576656
13BCOR_27268052_Chip-Seq_Bcells_Human1.86525172
14CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.86470663
15CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.83038409
16VDR_24763502_ChIP-Seq_THP-1_Human1.79746651
17* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.79339880
18YY1_22570637_ChIP-Seq_MALME-3M_Human1.75418099
19RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.73215950
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.68312377
21SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.66208366
22ELK3_25401928_ChIP-Seq_HUVEC_Human1.65750416
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.65556465
24EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.64576623
25PHF8_20622854_ChIP-Seq_HELA_Human1.63094408
26MYC_22102868_ChIP-Seq_BL_Human1.58056156
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.57902920
28CTCF_20526341_ChIP-Seq_ESCs_Human1.55601340
29RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.54403214
30STAT1_20625510_ChIP-Seq_HELA_Human1.53812021
31SA1_27219007_Chip-Seq_ERYTHROID_Human1.53807043
32LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52383604
33E2F1_20622854_ChIP-Seq_HELA_Human1.52265376
34SMC4_20622854_ChIP-Seq_HELA_Human1.51965203
35E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.50820491
36TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48882054
37SA1_27219007_Chip-Seq_Bcells_Human1.48700357
38JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.47979637
39KDM2B_26808549_Chip-Seq_DND41_Human1.46302230
40CTCF_27219007_Chip-Seq_Bcells_Human1.44299130
41SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.43706855
42SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.40863149
43SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.40735016
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39756884
45MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.39262812
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.37393290
47* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.37002608
48* KDM2B_26808549_Chip-Seq_K562_Human1.35876775
49CTCF_18555785_ChIP-Seq_MESCs_Mouse1.35490538
50SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.34073337
51TP53_22127205_ChIP-Seq_IMR90_Human1.33617659
52* MAF_26560356_Chip-Seq_TH2_Human1.33001321
53EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.31470468
54SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30023135
55* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.29003955
56CTCF_26484167_Chip-Seq_Bcells_Mouse1.28113633
57PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.24641973
58* ERA_21632823_ChIP-Seq_H3396_Human1.22898695
59RACK7_27058665_Chip-Seq_MCF-7_Human1.19631290
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18742528
61SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.18558702
62RARG_19884340_ChIP-ChIP_MEFs_Mouse1.18427823
63RAC3_21632823_ChIP-Seq_H3396_Human1.16650702
64NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16346889
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.15714510
66OCT4_19829295_ChIP-Seq_ESCs_Human1.15568914
67FOXP1_21924763_ChIP-Seq_HESCs_Human1.14814668
68CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.14591854
69SPI1_23127762_ChIP-Seq_K562_Human1.14540783
70TCF7_22412390_ChIP-Seq_EML_Mouse1.13538625
71SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.13125413
72SPI1_20517297_ChIP-Seq_HL60_Human1.12201226
73PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11797986
74CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.11042389
75GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.08816899
76IRF8_27001747_Chip-Seq_BMDM_Mouse1.08770530
77IRF8_21731497_ChIP-ChIP_J774_Mouse1.08596467
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.08046795
79CTCF_21964334_ChIP-Seq_BJAB-B_Human1.07617833
80LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07490083
81PU.1_20513432_ChIP-Seq_Bcells_Mouse1.07016859
82P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.06526474
83CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06040487
84* TP63_22573176_ChIP-Seq_HFKS_Human1.05081034
85SPI1_23547873_ChIP-Seq_NB4_Human1.04971122
86GABP_19822575_ChIP-Seq_HepG2_Human1.04067760
87P300_27268052_Chip-Seq_Bcells_Human1.03818059
88EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.03727161
89GATA1_22383799_ChIP-Seq_G1ME_Mouse1.01684349
90UTX_26944678_Chip-Seq_JUKART_Human1.01681441
91JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.01324895
92MAF_26560356_Chip-Seq_TH1_Human1.00064036
93MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.99885730
94RARA_24833708_ChIP-Seq_LIVER_Mouse0.99862837
95* KDM2B_26808549_Chip-Seq_JURKAT_Human0.99212717
96GATA3_21867929_ChIP-Seq_CD8_Mouse0.98612532
97MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.98566261
98FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97013904
99CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.96780566
100NANOG_20526341_ChIP-Seq_ESCs_Human0.96335506

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.98227542
2MP0009379_abnormal_foot_pigmentation3.99088020
3MP0003806_abnormal_nucleotide_metabolis3.73653204
4MP0009840_abnormal_foam_cell3.71544865
5MP0003172_abnormal_lysosome_physiology3.19917975
6MP0006082_CNS_inflammation2.97501780
7MP0003436_decreased_susceptibility_to2.94490414
8MP0002254_reproductive_system_inflammat2.79835933
9MP0003186_abnormal_redox_activity2.60683125
10MP0000685_abnormal_immune_system2.49666543
11MP0008260_abnormal_autophagy2.33470342
12MP0005410_abnormal_fertilization2.28994442
13MP0009764_decreased_sensitivity_to2.28986647
14MP0000604_amyloidosis2.20378972
15MP0006292_abnormal_olfactory_placode1.90020326
16MP0003878_abnormal_ear_physiology1.81511402
17MP0005377_hearing/vestibular/ear_phenot1.81511402
18MP0002419_abnormal_innate_immunity1.80672399
19MP0005025_abnormal_response_to1.75289991
20MP0005310_abnormal_salivary_gland1.74069523
21MP0002148_abnormal_hypersensitivity_rea1.72997952
22MP0003329_amyloid_beta_deposits1.66617326
23MP0002277_abnormal_respiratory_mucosa1.63465831
24MP0000343_altered_response_to1.62296183
25MP0003183_abnormal_peptide_metabolism1.56789374
26MP0005387_immune_system_phenotype1.55248449
27MP0001790_abnormal_immune_system1.55248449
28MP0004019_abnormal_vitamin_homeostasis1.51975185
29MP0009785_altered_susceptibility_to1.51413142
30MP0001873_stomach_inflammation1.50403058
31MP0005671_abnormal_response_to1.50149913
32MP0003303_peritoneal_inflammation1.47462649
33MP0001533_abnormal_skeleton_physiology1.43456709
34MP0009333_abnormal_splenocyte_physiolog1.43132340
35MP0002723_abnormal_immune_serum1.41471147
36MP0005000_abnormal_immune_tolerance1.39888494
37MP0010368_abnormal_lymphatic_system1.39819023
38MP0000015_abnormal_ear_pigmentation1.38450609
39MP0004510_myositis1.30981702
40MP0005166_decreased_susceptibility_to1.30594548
41MP0002452_abnormal_antigen_presenting1.29784223
42MP0002405_respiratory_system_inflammati1.28730972
43MP0001835_abnormal_antigen_presentation1.26090018
44MP0005394_taste/olfaction_phenotype1.23734863
45MP0005499_abnormal_olfactory_system1.23734863
46MP0004858_abnormal_nervous_system1.22897615
47MP0003075_altered_response_to1.22744167
48MP0008789_abnormal_olfactory_epithelium1.22192314
49MP0008469_abnormal_protein_level1.21476707
50MP0001800_abnormal_humoral_immune1.21476679
51MP0009278_abnormal_bone_marrow1.17040728
52MP0003879_abnormal_hair_cell1.15339655
53MP0001756_abnormal_urination1.12452389
54MP0002420_abnormal_adaptive_immunity1.11035916
55MP0001819_abnormal_immune_cell1.10785081
56MP0002229_neurodegeneration1.09767558
57MP0001663_abnormal_digestive_system1.08737135
58MP0001764_abnormal_homeostasis1.08683997
59MP0003646_muscle_fatigue1.08289204
60MP0006036_abnormal_mitochondrial_physio1.08017141
61MP0003828_pulmonary_edema1.07561718
62MP0003011_delayed_dark_adaptation1.06987243
63MP0001845_abnormal_inflammatory_respons1.06714853
64MP0005379_endocrine/exocrine_gland_phen1.02058217
65MP0000681_abnormal_thyroid_gland1.01970746
66MP0005464_abnormal_platelet_physiology0.95548885
67MP0000678_abnormal_parathyroid_gland0.95108726
68MP0000750_abnormal_muscle_regeneration0.93329567
69MP0002095_abnormal_skin_pigmentation0.93161406
70MP0003724_increased_susceptibility_to0.92472766
71MP0005174_abnormal_tail_pigmentation0.92222287
72MP0001440_abnormal_grooming_behavior0.85925806
73MP0005319_abnormal_enzyme/_coenzyme0.83970287
74MP0002127_abnormal_cardiovascular_syste0.81821557
75MP0008057_abnormal_DNA_replication0.78315599
76MP0000371_diluted_coat_color0.78187303
77MP0006072_abnormal_retinal_apoptosis0.76539781
78MP0000920_abnormal_myelination0.75979862
79MP0005390_skeleton_phenotype0.74732223
80MP0005408_hypopigmentation0.74718451
81MP0003634_abnormal_glial_cell0.74343908
82MP0002136_abnormal_kidney_physiology0.74039521
83MP0000716_abnormal_immune_system0.73565431
84MP0003191_abnormal_cellular_cholesterol0.73483430
85MP0005084_abnormal_gallbladder_morpholo0.70378353
86MP0003698_abnormal_male_reproductive0.69809167
87MP0002998_abnormal_bone_remodeling0.69014448
88MP0005423_abnormal_somatic_nervous0.69009108
89MP0005075_abnormal_melanosome_morpholog0.67471202
90MP0002139_abnormal_hepatobiliary_system0.67352459
91MP0002736_abnormal_nociception_after0.67071039
92MP0003453_abnormal_keratinocyte_physiol0.66701626
93MP0002429_abnormal_blood_cell0.66613432
94MP0009053_abnormal_anal_canal0.66101940
95MP0001968_abnormal_touch/_nociception0.66010509
96MP0000470_abnormal_stomach_morphology0.65475838
97MP0000689_abnormal_spleen_morphology0.65329850
98MP0000490_abnormal_crypts_of0.64428955
99MP0002132_abnormal_respiratory_system0.60482393
100MP0005365_abnormal_bile_salt0.60295044

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of liposaccharide metabolism (HP:0010968)6.55608895
2Abnormality of glycosphingolipid metabolism (HP:0004343)6.55608895
3Abnormality of glycolipid metabolism (HP:0010969)6.55608895
4Nuclear cataract (HP:0100018)4.92450955
5Axonal loss (HP:0003447)4.38612100
6Recurrent abscess formation (HP:0002722)4.22369685
7Increased cerebral lipofuscin (HP:0011813)4.09570159
8Tetany (HP:0001281)3.83540686
9Prolonged neonatal jaundice (HP:0006579)3.76354402
10Disinhibition (HP:0000734)3.74826330
11Recurrent bacterial skin infections (HP:0005406)3.74069937
12Systemic lupus erythematosus (HP:0002725)3.64390976
13Increased neuronal autofluorescent lipopigment (HP:0002074)3.62830234
14Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.59379291
15Vacuolated lymphocytes (HP:0001922)3.44155515
16Aplasia/Hypoplasia of the sacrum (HP:0008517)3.43890041
17Dysostosis multiplex (HP:0000943)3.27637716
18Mutism (HP:0002300)3.23476339
19Abnormality of macrophages (HP:0004311)3.21611584
20Reticulocytopenia (HP:0001896)3.11765047
21Abnormality of magnesium homeostasis (HP:0004921)3.11646676
22Upper motor neuron abnormality (HP:0002127)3.03425677
23Loss of speech (HP:0002371)2.99151597
24Severe visual impairment (HP:0001141)2.95373100
25Purpura (HP:0000979)2.94466318
26Stomatitis (HP:0010280)2.93967229
27Retinal atrophy (HP:0001105)2.93291465
28Obstructive lung disease (HP:0006536)2.83947329
29Chronic obstructive pulmonary disease (HP:0006510)2.83947329
30Abnormality of the aortic arch (HP:0012303)2.83805952
31Thoracic kyphosis (HP:0002942)2.81802690
32Polydipsia (HP:0001959)2.75023217
33Abnormal drinking behavior (HP:0030082)2.75023217
34Renal Fanconi syndrome (HP:0001994)2.58453986
35Hypomagnesemia (HP:0002917)2.52480301
36Myositis (HP:0100614)2.39002283
37Eczematoid dermatitis (HP:0000976)2.36365773
38Multiple enchondromatosis (HP:0005701)2.35840052
39Neurofibrillary tangles (HP:0002185)2.35745181
40Polyuria (HP:0000103)2.35033336
41Inappropriate behavior (HP:0000719)2.34378774
42Hepatosplenomegaly (HP:0001433)2.30493189
43Abnormality of the thoracic spine (HP:0100711)2.25691454
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.23854020
45Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.22812520
46Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.21261348
47Recurrent skin infections (HP:0001581)2.19742385
48Supranuclear gaze palsy (HP:0000605)2.18438800
49Abnormality of mucopolysaccharide metabolism (HP:0011020)2.16811835
50Abnormality of polysaccharide metabolism (HP:0011012)2.16811835
51Abnormality of glycosaminoglycan metabolism (HP:0004371)2.16811835
52Abnormal rod and cone electroretinograms (HP:0008323)2.16464631
53Opisthotonus (HP:0002179)2.15067911
54Gingivitis (HP:0000230)2.15058976
55Recurrent gram-negative bacterial infections (HP:0005420)2.14523464
56Abnormal urine output (HP:0012590)2.12639209
57Amyloidosis (HP:0011034)2.12268434
58Abnormality of the vertebral endplates (HP:0005106)2.11599429
59Abnormality of DNA repair (HP:0003254)2.09993115
60Flattened epiphyses (HP:0003071)2.08868623
61Mediastinal lymphadenopathy (HP:0100721)2.08351112
62Personality changes (HP:0000751)2.06727571
63Parakeratosis (HP:0001036)2.06340046
64Abnormality of the nasal mucosa (HP:0000433)2.02678984
65Increased serum ferritin (HP:0003281)2.01674233
66Dementia (HP:0000726)2.00948800
67Petechiae (HP:0000967)1.98392580
68Abnormality of the vasculature of the conjunctiva (HP:0008054)1.92963785
69Abnormality of lateral ventricle (HP:0030047)1.92590815
70Glomerulonephritis (HP:0000099)1.90087159
71Microretrognathia (HP:0000308)1.88231837
72Respiratory difficulties (HP:0002880)1.86484588
73Mucopolysacchariduria (HP:0008155)1.85921243
74Urinary glycosaminoglycan excretion (HP:0003541)1.85921243
75Agnosia (HP:0010524)1.85661233
76Elevated erythrocyte sedimentation rate (HP:0003565)1.84250580
77Progressive neurologic deterioration (HP:0002344)1.83616567
78Retinal dysplasia (HP:0007973)1.81066147
79Polygenic inheritance (HP:0010982)1.80353919
80Pathologic fracture (HP:0002756)1.80243217
81Acute encephalopathy (HP:0006846)1.79297658
82Pustule (HP:0200039)1.74719067
83Pendular nystagmus (HP:0012043)1.74110772
84Abnormality of renal excretion (HP:0011036)1.73802399
85Cerebral inclusion bodies (HP:0100314)1.72386458
86Protuberant abdomen (HP:0001538)1.71200634
87Vertebral compression fractures (HP:0002953)1.69663804
88Macrocytic anemia (HP:0001972)1.69491751
89Rib fusion (HP:0000902)1.69345289
90Exertional dyspnea (HP:0002875)1.68660506
91Albinism (HP:0001022)1.67543832
92Pallor (HP:0000980)1.67243414
93Abnormality of the motor neurons (HP:0002450)1.66926797
94Abnormal neuron morphology (HP:0012757)1.66926797
95Flat capital femoral epiphysis (HP:0003370)1.66866072
96Aplasia/Hypoplasia of the spleen (HP:0010451)1.66533866
97Mitochondrial inheritance (HP:0001427)1.66233022
98Hyperthyroidism (HP:0000836)1.64768002
99Broad distal phalanx of finger (HP:0009836)1.64351521
100Hypertensive crisis (HP:0100735)1.62396006

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.89917476
2NME23.78161688
3MAP3K112.85664919
4TAOK12.53889702
5CDK192.48054574
6STK162.41377243
7MAP4K12.16504158
8DDR22.09203783
9TYRO32.06789146
10TAOK22.04232719
11MAP4K22.01982649
12ARAF2.01844349
13BRAF2.00556419
14MAP2K31.95562231
15TESK11.94855979
16ACVR1B1.78089518
17PRKD21.75523373
18MARK21.75453611
19ABL21.60478308
20MAP3K131.55078169
21TESK21.53337387
22CAMK1D1.51847988
23EPHB21.51392905
24SMG11.51016580
25BLK1.45246551
26TBK11.39684667
27DYRK21.39314964
28SIK21.38078034
29TNK21.37231028
30TGFBR21.37210853
31HIPK21.35724315
32DYRK31.31054184
33IRAK31.26025073
34TYK21.21852987
35MARK31.21369048
36GRK61.17288939
37TRIB31.13600765
38PIM21.06158374
39IKBKB1.05871732
40DAPK21.05686433
41GRK71.04528394
42GRK51.03740777
43RIPK41.02437686
44MAP3K81.02095740
45STK381.01361194
46MATK1.00049414
47CAMKK10.97130238
48EPHA40.96331744
49CAMK1G0.94282545
50NTRK30.90327110
51IRAK40.89759664
52TIE10.88625052
53TLK10.88128486
54VRK20.86461878
55CAMK10.84677474
56MAP3K140.83730359
57PDK20.83094469
58OXSR10.82473964
59SIK30.82089046
60MAP3K70.80287974
61TGFBR10.79345969
62LIMK10.78116251
63DYRK1B0.76625209
64PDPK10.73069383
65CAMKK20.73032961
66MAP3K30.71340093
67CASK0.70010230
68WNK40.65008430
69KSR20.64892735
70CDK90.64569523
71KSR10.63291783
72PDK10.62772899
73DAPK30.59063217
74RPS6KC10.57230483
75RPS6KL10.57230483
76MAP2K60.56866664
77PRKCI0.55864945
78MOS0.54363894
79CDK40.53696688
80SGK4940.53243101
81SGK2230.53243101
82MAP3K10.53095856
83CSF1R0.52472860
84RPS6KA60.50845815
85CAMK40.50279150
86ADRBK20.50138790
87NTRK20.49071922
88SIK10.49001831
89KDR0.48902711
90FGR0.47515934
91CSK0.45597643
92BTK0.45521861
93AKT30.45134035
94MAP3K60.43871618
95IKBKE0.43450262
96PRKD30.42510663
97LYN0.40624072
98TAOK30.36720413
99SYK0.36367701
100FES0.34661967

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005115.25245703
2Sulfur relay system_Homo sapiens_hsa041224.22371002
3Glycosaminoglycan degradation_Homo sapiens_hsa005313.57121105
4Lysosome_Homo sapiens_hsa041423.48122420
5Ribosome_Homo sapiens_hsa030102.86471773
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.63924213
7Collecting duct acid secretion_Homo sapiens_hsa049662.39936880
8Staphylococcus aureus infection_Homo sapiens_hsa051502.32007313
9Osteoclast differentiation_Homo sapiens_hsa043802.30442641
10Allograft rejection_Homo sapiens_hsa053301.80923294
11Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.80150166
12Phagosome_Homo sapiens_hsa041451.78772116
13Folate biosynthesis_Homo sapiens_hsa007901.66463432
14Rheumatoid arthritis_Homo sapiens_hsa053231.64401576
15Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.63757009
16Tuberculosis_Homo sapiens_hsa051521.61218942
17Leishmaniasis_Homo sapiens_hsa051401.55385918
18Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.52663699
19Vitamin B6 metabolism_Homo sapiens_hsa007501.50787004
20Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.50529045
21Synaptic vesicle cycle_Homo sapiens_hsa047211.48898608
22Antigen processing and presentation_Homo sapiens_hsa046121.47900918
23Toll-like receptor signaling pathway_Homo sapiens_hsa046201.47879165
24Autoimmune thyroid disease_Homo sapiens_hsa053201.40200097
25Asthma_Homo sapiens_hsa053101.39373141
26Cyanoamino acid metabolism_Homo sapiens_hsa004601.38892919
27Vibrio cholerae infection_Homo sapiens_hsa051101.35458063
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.26441641
29Glutathione metabolism_Homo sapiens_hsa004801.24863236
30Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.23522733
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.23203570
32Graft-versus-host disease_Homo sapiens_hsa053321.22617463
33Legionellosis_Homo sapiens_hsa051341.19767943
34Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.18956804
35Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.18491241
36Notch signaling pathway_Homo sapiens_hsa043301.16777530
37Regulation of autophagy_Homo sapiens_hsa041401.15981436
38Intestinal immune network for IgA production_Homo sapiens_hsa046721.13686414
39Oxidative phosphorylation_Homo sapiens_hsa001901.13547154
40Bladder cancer_Homo sapiens_hsa052191.07326424
41Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04253193
42NF-kappa B signaling pathway_Homo sapiens_hsa040641.04075847
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.03854589
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.03470768
45Type I diabetes mellitus_Homo sapiens_hsa049401.01641854
46African trypanosomiasis_Homo sapiens_hsa051431.01346728
47Malaria_Homo sapiens_hsa051441.00639216
48Prion diseases_Homo sapiens_hsa050200.95978956
49Salmonella infection_Homo sapiens_hsa051320.95696724
50B cell receptor signaling pathway_Homo sapiens_hsa046620.93579975
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.92650270
52Pertussis_Homo sapiens_hsa051330.92075656
53TNF signaling pathway_Homo sapiens_hsa046680.91108608
54VEGF signaling pathway_Homo sapiens_hsa043700.79186552
55Toxoplasmosis_Homo sapiens_hsa051450.77827609
56Huntingtons disease_Homo sapiens_hsa050160.74700404
57SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73815743
58RNA polymerase_Homo sapiens_hsa030200.73405973
59Endocytosis_Homo sapiens_hsa041440.72461665
60Chemokine signaling pathway_Homo sapiens_hsa040620.70853686
61Primary immunodeficiency_Homo sapiens_hsa053400.69441870
62Sphingolipid metabolism_Homo sapiens_hsa006000.67023780
63Galactose metabolism_Homo sapiens_hsa000520.65477476
64Apoptosis_Homo sapiens_hsa042100.62537020
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61667647
66Epstein-Barr virus infection_Homo sapiens_hsa051690.59398716
67Parkinsons disease_Homo sapiens_hsa050120.58614350
68Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.57375703
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54820361
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54819063
71Hematopoietic cell lineage_Homo sapiens_hsa046400.54544950
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53971089
73Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.53476485
74Base excision repair_Homo sapiens_hsa034100.51404426
75Arginine and proline metabolism_Homo sapiens_hsa003300.50251927
76Arachidonic acid metabolism_Homo sapiens_hsa005900.50053715
77Mineral absorption_Homo sapiens_hsa049780.49426580
78Viral myocarditis_Homo sapiens_hsa054160.49012226
79Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48407892
80Influenza A_Homo sapiens_hsa051640.46716366
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43838693
82Hepatitis C_Homo sapiens_hsa051600.42440506
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.42268989
84Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40715740
85Adipocytokine signaling pathway_Homo sapiens_hsa049200.39745496
86Hepatitis B_Homo sapiens_hsa051610.36392522
87Acute myeloid leukemia_Homo sapiens_hsa052210.36333964
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35328146
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34215853
90HIF-1 signaling pathway_Homo sapiens_hsa040660.32953263
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31887999
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.27736363
93Shigellosis_Homo sapiens_hsa051310.26740233
94Peroxisome_Homo sapiens_hsa041460.25372353
95Phospholipase D signaling pathway_Homo sapiens_hsa040720.24501032
96Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.24070264
97Metabolic pathways_Homo sapiens_hsa011000.23977587
98Glycerolipid metabolism_Homo sapiens_hsa005610.23662662
99Herpes simplex infection_Homo sapiens_hsa051680.23329688
100Pyrimidine metabolism_Homo sapiens_hsa002400.17356203

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »