CENPCP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tolerance induction (GO:0002507)5.49402903
2sleep (GO:0030431)4.84663387
3positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.76889031
4tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.74133759
5RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.74133759
6cellular response to interleukin-15 (GO:0071350)4.49342739
7kinetochore assembly (GO:0051382)4.29010612
8negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)4.06797636
9dendritic cell chemotaxis (GO:0002407)3.97515682
10DNA deamination (GO:0045006)3.91049791
11positive regulation of alpha-beta T cell proliferation (GO:0046641)3.90806702
12positive regulation of T-helper 1 type immune response (GO:0002827)3.88641829
13behavioral response to nicotine (GO:0035095)3.87375615
14response to interleukin-15 (GO:0070672)3.78680251
15response to gravity (GO:0009629)3.77734964
16regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.75302302
17positive regulation of oligodendrocyte differentiation (GO:0048714)3.63266898
18mast cell degranulation (GO:0043303)3.61841779
19mast cell activation involved in immune response (GO:0002279)3.61841779
20mast cell activation (GO:0045576)3.59388447
21positive regulation of T cell mediated cytotoxicity (GO:0001916)3.57637061
22CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.55441966
23T-helper cell differentiation (GO:0042093)3.55441966
24dendritic cell migration (GO:0036336)3.54058778
25regulation of T cell mediated cytotoxicity (GO:0001914)3.51143361
26regulation of T-helper 1 type immune response (GO:0002825)3.49610209
27negative regulation of bone resorption (GO:0045779)3.43394655
28regulation of alpha-beta T cell proliferation (GO:0046640)3.40305676
29negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.31992940
30negative regulation of cell killing (GO:0031342)3.31992940
31cyclooxygenase pathway (GO:0019371)3.27851568
32negative T cell selection (GO:0043383)3.25991510
33kinetochore organization (GO:0051383)3.19868294
34preassembly of GPI anchor in ER membrane (GO:0016254)3.18673277
35protein K11-linked deubiquitination (GO:0035871)3.18396253
36platelet dense granule organization (GO:0060155)3.16384001
37T cell differentiation involved in immune response (GO:0002292)3.16132192
38alpha-beta T cell differentiation involved in immune response (GO:0002293)3.16132192
39alpha-beta T cell activation involved in immune response (GO:0002287)3.16132192
40negative thymic T cell selection (GO:0045060)3.15667879
41regulation of memory T cell differentiation (GO:0043380)3.14624468
42negative regulation of DNA-templated transcription, elongation (GO:0032785)3.13423741
43positive regulation of defense response to virus by host (GO:0002230)3.05927264
44antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.04259213
45negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.00750335
46regulation of T cell receptor signaling pathway (GO:0050856)3.00593407
47fucose catabolic process (GO:0019317)2.99759752
48L-fucose metabolic process (GO:0042354)2.99759752
49L-fucose catabolic process (GO:0042355)2.99759752
50mannosylation (GO:0097502)2.97284292
51detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.97057729
52positive regulation of fatty acid transport (GO:2000193)2.96513517
53growth hormone receptor signaling pathway (GO:0060396)2.95303915
54regulation of prostaglandin secretion (GO:0032306)2.95060228
55positive regulation of prostaglandin secretion (GO:0032308)2.94586968
56purinergic nucleotide receptor signaling pathway (GO:0035590)2.93696263
57regulation of defense response to virus by host (GO:0050691)2.93460995
58regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.92876354
59regulation of germinal center formation (GO:0002634)2.91355522
60somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.86081223
61isotype switching (GO:0045190)2.86081223
62somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.86081223
63positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.84652489
64positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.83417580
65regulation of isotype switching to IgG isotypes (GO:0048302)2.81199263
66RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.80949532
67regulation of B cell receptor signaling pathway (GO:0050855)2.79802995
68regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.77655521
69regulation of mitotic spindle checkpoint (GO:1903504)2.77655521
70positive regulation of icosanoid secretion (GO:0032305)2.75931029
71piRNA metabolic process (GO:0034587)2.75217022
72regulation of regulatory T cell differentiation (GO:0045589)2.73207721
73cellular response to growth hormone stimulus (GO:0071378)2.68193385
74S-adenosylmethionine metabolic process (GO:0046500)2.67252754
75negative regulation of mast cell activation (GO:0033004)2.66736205
76thrombin receptor signaling pathway (GO:0070493)2.66263998
77regulation of cellular extravasation (GO:0002691)2.63755509
78negative regulation of bone remodeling (GO:0046851)2.62659210
79regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.62492865
80cytidine deamination (GO:0009972)2.60139722
81cytidine metabolic process (GO:0046087)2.60139722
82cytidine catabolic process (GO:0006216)2.60139722
83base-excision repair, AP site formation (GO:0006285)2.59668465
84positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.58706475
85endoderm formation (GO:0001706)2.57854294
86sequestering of actin monomers (GO:0042989)2.57822087
87regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.57482436
88chemokine-mediated signaling pathway (GO:0070098)2.56708912
89GPI anchor metabolic process (GO:0006505)2.54300612
90neutrophil activation (GO:0042119)2.54127998
91kynurenine metabolic process (GO:0070189)2.53713289
92regulation of leukocyte mediated cytotoxicity (GO:0001910)2.51859443
93leukotriene biosynthetic process (GO:0019370)2.51794364
94regulation of T cell chemotaxis (GO:0010819)2.51447610
95positive regulation of T cell chemotaxis (GO:0010820)2.51447610
96regulation of cell killing (GO:0031341)2.48489708
97nephron epithelium morphogenesis (GO:0072088)2.47941618
98nephron tubule morphogenesis (GO:0072078)2.47941618
99adenosine metabolic process (GO:0046085)2.47495296
100auditory receptor cell stereocilium organization (GO:0060088)2.47409603

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.16114911
2VDR_22108803_ChIP-Seq_LS180_Human3.44754734
3ZNF274_21170338_ChIP-Seq_K562_Hela3.14327745
4FLI1_27457419_Chip-Seq_LIVER_Mouse3.04073005
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.00421426
6IRF8_22096565_ChIP-ChIP_GC-B_Human2.65725455
7PCGF2_27294783_Chip-Seq_ESCs_Mouse2.33649654
8NOTCH1_21737748_ChIP-Seq_TLL_Human2.29861796
9TAF15_26573619_Chip-Seq_HEK293_Human2.25527552
10RUNX_20019798_ChIP-Seq_JUKART_Human2.18960287
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.13857156
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.10632543
13IGF1R_20145208_ChIP-Seq_DFB_Human2.08340466
14GATA3_26560356_Chip-Seq_TH2_Human2.07442582
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.01471262
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.94452464
17VDR_23849224_ChIP-Seq_CD4+_Human1.91096149
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.87400294
19GBX2_23144817_ChIP-Seq_PC3_Human1.85719775
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.84551276
21ELF1_17652178_ChIP-ChIP_JURKAT_Human1.80061847
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79463444
23IRF1_19129219_ChIP-ChIP_H3396_Human1.74857374
24MYB_26560356_Chip-Seq_TH2_Human1.72510339
25GABP_17652178_ChIP-ChIP_JURKAT_Human1.72426219
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.71667280
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.69731901
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.69619951
29SUZ12_27294783_Chip-Seq_NPCs_Mouse1.69540960
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.67377972
31EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67257545
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.58717709
33EZH2_27294783_Chip-Seq_NPCs_Mouse1.58561939
34IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.55381875
35EWS_26573619_Chip-Seq_HEK293_Human1.54518320
36AR_20517297_ChIP-Seq_VCAP_Human1.52866817
37TP53_22573176_ChIP-Seq_HFKS_Human1.50104853
38LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.49605832
39ER_23166858_ChIP-Seq_MCF-7_Human1.48567842
40P300_19829295_ChIP-Seq_ESCs_Human1.48238734
41CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.47625817
42EST1_17652178_ChIP-ChIP_JURKAT_Human1.47198467
43CBP_20019798_ChIP-Seq_JUKART_Human1.46316718
44IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46316718
45GATA3_27048872_Chip-Seq_THYMUS_Human1.45254407
46FUS_26573619_Chip-Seq_HEK293_Human1.45035100
47ELK1_19687146_ChIP-ChIP_HELA_Human1.39911355
48MYC_18940864_ChIP-ChIP_HL60_Human1.39898129
49PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39441895
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38349656
51BCAT_22108803_ChIP-Seq_LS180_Human1.34279038
52FOXA1_21572438_ChIP-Seq_LNCaP_Human1.33285256
53CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.31010123
54BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.29321389
55CRX_20693478_ChIP-Seq_RETINA_Mouse1.28743184
56SCL_19346495_ChIP-Seq_HPC-7_Human1.28422543
57PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.28261165
58IRF8_21731497_ChIP-ChIP_J774_Mouse1.27482884
59EZH2_22144423_ChIP-Seq_EOC_Human1.27012817
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26885879
61FOXA1_27270436_Chip-Seq_PROSTATE_Human1.25563795
62FOXA1_25329375_ChIP-Seq_VCAP_Human1.25563795
63PRDM14_20953172_ChIP-Seq_ESCs_Human1.20663765
64SOX2_19829295_ChIP-Seq_ESCs_Human1.19067030
65NANOG_19829295_ChIP-Seq_ESCs_Human1.19067030
66KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.18413762
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18335655
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18335655
69SRF_21415370_ChIP-Seq_HL-1_Mouse1.15339421
70TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.14614000
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13412913
72SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.13235885
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12735036
74FOXP3_21729870_ChIP-Seq_TREG_Human1.12424608
75GATA3_26560356_Chip-Seq_TH1_Human1.11252223
76TCF4_22108803_ChIP-Seq_LS180_Human1.09435589
77P53_22387025_ChIP-Seq_ESCs_Mouse1.09344460
78SMAD4_21799915_ChIP-Seq_A2780_Human1.08924189
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07821688
80TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.07059419
81RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.06962536
82PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05991137
83OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05540344
84PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.04275135
85NANOG_20526341_ChIP-Seq_ESCs_Human1.04245023
86GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.02767574
87STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.01031381
88STAT3_18555785_Chip-Seq_ESCs_Mouse1.00796391
89AR_25329375_ChIP-Seq_VCAP_Human1.00337733
90PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00235215
91GATA3_21878914_ChIP-Seq_MCF-7_Human0.99259111
92SALL1_21062744_ChIP-ChIP_HESCs_Human0.98930514
93TCF4_23295773_ChIP-Seq_U87_Human0.97793364
94CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95651991
95NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95402605
96NANOG_18555785_Chip-Seq_ESCs_Mouse0.94679474
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94474548
98TAL1_26923725_Chip-Seq_HPCs_Mouse0.93668274
99HOXB7_26014856_ChIP-Seq_BT474_Human0.93036623
100GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93017852

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to3.71270017
2MP0003724_increased_susceptibility_to3.25970263
3MP0000569_abnormal_digit_pigmentation3.22205262
4MP0004147_increased_porphyrin_level3.18319571
5MP0006072_abnormal_retinal_apoptosis2.71123682
6MP0002009_preneoplasia2.61164291
7MP0005075_abnormal_melanosome_morpholog2.51142067
8MP0005084_abnormal_gallbladder_morpholo2.40723512
9MP0002102_abnormal_ear_morphology2.36989427
10MP0004885_abnormal_endolymph2.22984529
11MP0005000_abnormal_immune_tolerance2.09863861
12MP0003763_abnormal_thymus_physiology2.04552652
13MP0002138_abnormal_hepatobiliary_system2.03138899
14MP0003866_abnormal_defecation1.97208929
15MP0003195_calcinosis1.88332256
16MP0008877_abnormal_DNA_methylation1.81070727
17MP0005646_abnormal_pituitary_gland1.80009640
18MP0003878_abnormal_ear_physiology1.79997532
19MP0005377_hearing/vestibular/ear_phenot1.79997532
20MP0001968_abnormal_touch/_nociception1.79490865
21MP0003436_decreased_susceptibility_to1.79165146
22MP0002876_abnormal_thyroid_physiology1.77757155
23MP0001800_abnormal_humoral_immune1.76958580
24MP0008872_abnormal_physiological_respon1.76904927
25MP0001501_abnormal_sleep_pattern1.74407770
26MP0002148_abnormal_hypersensitivity_rea1.73994899
27MP0002166_altered_tumor_susceptibility1.73158410
28MP0000372_irregular_coat_pigmentation1.71588431
29MP0005174_abnormal_tail_pigmentation1.71544502
30MP0009785_altered_susceptibility_to1.70322114
31MP0000465_gastrointestinal_hemorrhage1.67370071
32MP0002163_abnormal_gland_morphology1.65793902
33MP0002723_abnormal_immune_serum1.64745827
34MP0001835_abnormal_antigen_presentation1.59820557
35MP0005645_abnormal_hypothalamus_physiol1.47637866
36MP0002736_abnormal_nociception_after1.43996909
37MP0004043_abnormal_pH_regulation1.41215998
38MP0002272_abnormal_nervous_system1.40749808
39MP0001919_abnormal_reproductive_system1.40611521
40MP0004142_abnormal_muscle_tone1.37891553
41MP0000427_abnormal_hair_cycle1.36748403
42MP0002452_abnormal_antigen_presenting1.36556633
43MP0005253_abnormal_eye_physiology1.35104767
44MP0005551_abnormal_eye_electrophysiolog1.34785392
45MP0001819_abnormal_immune_cell1.32728376
46MP0000685_abnormal_immune_system1.32089279
47MP0002420_abnormal_adaptive_immunity1.28320948
48MP0001243_abnormal_dermal_layer1.26512020
49MP0001986_abnormal_taste_sensitivity1.26406883
50MP0009745_abnormal_behavioral_response1.25292115
51MP0002006_tumorigenesis1.20468649
52MP0009764_decreased_sensitivity_to1.18592734
53MP0005167_abnormal_blood-brain_barrier1.18484066
54MP0006276_abnormal_autonomic_nervous1.18393905
55MP0005379_endocrine/exocrine_gland_phen1.17038479
56MP0001533_abnormal_skeleton_physiology1.10955909
57MP0002095_abnormal_skin_pigmentation1.07397792
58MP0001486_abnormal_startle_reflex1.06090913
59MP0001542_abnormal_bone_strength1.05059324
60MP0001845_abnormal_inflammatory_respons1.04517572
61MP0004742_abnormal_vestibular_system1.01511086
62MP0002933_joint_inflammation1.00744138
63MP0008875_abnormal_xenobiotic_pharmacok1.00551076
64MP0001790_abnormal_immune_system0.98280396
65MP0005387_immune_system_phenotype0.98280396
66MP0001765_abnormal_ion_homeostasis0.97207277
67MP0006292_abnormal_olfactory_placode0.96969422
68MP0004145_abnormal_muscle_electrophysio0.96580469
69MP0000015_abnormal_ear_pigmentation0.96285822
70MP0002419_abnormal_innate_immunity0.94332951
71MP0003787_abnormal_imprinting0.94232184
72MP0000230_abnormal_systemic_arterial0.94028414
73MP0010155_abnormal_intestine_physiology0.92978913
74MP0003638_abnormal_response/metabolism_0.91962924
75MP0010386_abnormal_urinary_bladder0.91585707
76MP0002938_white_spotting0.90972516
77MP0000716_abnormal_immune_system0.90370699
78MP0005025_abnormal_response_to0.90017683
79MP0003283_abnormal_digestive_organ0.89256822
80MP0009333_abnormal_splenocyte_physiolog0.87422639
81MP0000383_abnormal_hair_follicle0.86312057
82MP0000013_abnormal_adipose_tissue0.85994556
83MP0000689_abnormal_spleen_morphology0.85320805
84MP0005389_reproductive_system_phenotype0.84547990
85MP0002398_abnormal_bone_marrow0.82751033
86MP0005332_abnormal_amino_acid0.81483241
87MP0001529_abnormal_vocalization0.81226504
88MP0002572_abnormal_emotion/affect_behav0.80361164
89MP0000639_abnormal_adrenal_gland0.79944623
90MP0004381_abnormal_hair_follicle0.79879461
91MP0002722_abnormal_immune_system0.79854038
92MP0001970_abnormal_pain_threshold0.78968564
93MP0003329_amyloid_beta_deposits0.77638298
94MP0001440_abnormal_grooming_behavior0.75676050
95MP0002557_abnormal_social/conspecific_i0.75547758
96MP0005085_abnormal_gallbladder_physiolo0.74899312
97MP0003879_abnormal_hair_cell0.74492143
98MP0002733_abnormal_thermal_nociception0.71441414
99MP0000604_amyloidosis0.71264461
100MP0002638_abnormal_pupillary_reflex0.71198781

Predicted human phenotypes

RankGene SetZ-score
1IgG deficiency (HP:0004315)5.29787033
2Severe combined immunodeficiency (HP:0004430)3.25580934
3Stomach cancer (HP:0012126)3.19009580
4Abnormality of eosinophils (HP:0001879)3.11660992
5B lymphocytopenia (HP:0010976)3.08523589
6Abnormality of B cell number (HP:0010975)3.07029446
7Stomatitis (HP:0010280)3.06778225
8T lymphocytopenia (HP:0005403)3.05973372
9Abnormality of T cell number (HP:0011839)3.01088024
10Abnormality of T cells (HP:0002843)2.98545117
11Abnormality of the renal cortex (HP:0011035)2.98290886
12Joint swelling (HP:0001386)2.95165057
13Renal cortical cysts (HP:0000803)2.95111083
14Pancreatic cysts (HP:0001737)2.84124715
15Abnormality of T cell physiology (HP:0011840)2.83049868
16Congenital stationary night blindness (HP:0007642)2.76069716
17Growth hormone excess (HP:0000845)2.74372087
18Cerebral palsy (HP:0100021)2.72538834
19Prostate neoplasm (HP:0100787)2.70020724
20Thyroiditis (HP:0100646)2.69615855
21Conical tooth (HP:0000698)2.66855515
22Hypokalemic alkalosis (HP:0001949)2.65049914
23Aplasia/hypoplasia of the uterus (HP:0008684)2.64172293
24Molar tooth sign on MRI (HP:0002419)2.59917612
25Abnormality of midbrain morphology (HP:0002418)2.59917612
263-Methylglutaconic aciduria (HP:0003535)2.49500001
27Panhypogammaglobulinemia (HP:0003139)2.48555073
28Metabolic alkalosis (HP:0200114)2.47953164
29Eosinophilia (HP:0001880)2.47362932
30Combined immunodeficiency (HP:0005387)2.46660704
31IgM deficiency (HP:0002850)2.45312469
32Nephronophthisis (HP:0000090)2.45258312
33Hypomagnesemia (HP:0002917)2.44650094
34Clumsiness (HP:0002312)2.43253819
35Medial flaring of the eyebrow (HP:0010747)2.39844355
36Abolished electroretinogram (ERG) (HP:0000550)2.37288112
37Congenital, generalized hypertrichosis (HP:0004540)2.36798478
38Thyroid-stimulating hormone excess (HP:0002925)2.36535362
39True hermaphroditism (HP:0010459)2.35805384
40Elevated erythrocyte sedimentation rate (HP:0003565)2.33988858
41Hypothermia (HP:0002045)2.33562771
42Increased circulating renin level (HP:0000848)2.33224459
43Methylmalonic acidemia (HP:0002912)2.32778891
44Recurrent bronchitis (HP:0002837)2.30359225
45Abnormality of the renal medulla (HP:0100957)2.26115193
46Abnormality of the prostate (HP:0008775)2.24669714
47Hypoplasia of the pons (HP:0012110)2.24146065
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.23346271
49Myositis (HP:0100614)2.23288204
50Dyskinesia (HP:0100660)2.17718530
51Neutropenia (HP:0001875)2.15429192
52Abnormal delayed hypersensitivity skin test (HP:0002963)2.15262394
53Progressive microcephaly (HP:0000253)2.13716368
54Type II lissencephaly (HP:0007260)2.13683927
55Polyuria (HP:0000103)2.11205122
56Alkalosis (HP:0001948)2.11171807
57Abnormal drinking behavior (HP:0030082)2.09872184
58Polydipsia (HP:0001959)2.09872184
59Granulocytopenia (HP:0001913)2.08892565
60Abnormality of the pons (HP:0007361)2.06285603
61Pancreatic fibrosis (HP:0100732)2.03837384
62Leukocytosis (HP:0001974)2.02416531
63Hypoproteinemia (HP:0003075)1.99997579
64Hematochezia (HP:0002573)1.99953254
65Aplasia/Hypoplasia of the tibia (HP:0005772)1.99043191
66Pustule (HP:0200039)1.98785762
67Short tibia (HP:0005736)1.98392862
68Hypoplasia of the uterus (HP:0000013)1.95906752
69Abnormal rod and cone electroretinograms (HP:0008323)1.95782604
70Aplasia/Hypoplasia of the spleen (HP:0010451)1.94547411
71Tetany (HP:0001281)1.93452023
72Carpal bone hypoplasia (HP:0001498)1.92980892
73Asplenia (HP:0001746)1.91705857
74Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.90023026
75Pulmonary fibrosis (HP:0002206)1.89993202
76Eczematoid dermatitis (HP:0000976)1.89459366
77Constricted visual fields (HP:0001133)1.87678098
78Tongue fasciculations (HP:0001308)1.87647175
79Congenital primary aphakia (HP:0007707)1.84802488
80Gait imbalance (HP:0002141)1.82764817
81Ketoacidosis (HP:0001993)1.80236615
82Chronic mucocutaneous candidiasis (HP:0002728)1.79056267
83Recurrent cutaneous fungal infections (HP:0011370)1.79056267
84Attenuation of retinal blood vessels (HP:0007843)1.77505934
85Aplasia/Hypoplasia of the fovea (HP:0008060)1.75684288
86Hypoplasia of the fovea (HP:0007750)1.75684288
87Facial diplegia (HP:0001349)1.75448461
88Optic neuritis (HP:0100653)1.75119958
89Retrobulbar optic neuritis (HP:0100654)1.75119958
90Hypokalemia (HP:0002900)1.75119007
91Hyperalaninemia (HP:0003348)1.74163488
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74163488
93Abnormality of alanine metabolism (HP:0010916)1.74163488
94Abnormal urine output (HP:0012590)1.72107572
95Delayed CNS myelination (HP:0002188)1.70616407
96Abnormality of dental color (HP:0011073)1.70592883
97Abnormality of renin-angiotensin system (HP:0000847)1.70320737
98Erythroderma (HP:0001019)1.69675644
99Nephrogenic diabetes insipidus (HP:0009806)1.68256496
100Keratoconjunctivitis (HP:0001096)1.66254953

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK38.61815058
2MAP4K26.37956298
3GRK62.90093394
4TXK2.43302328
5MAP2K22.31614291
6FRK2.30037554
7TLK12.22068046
8ADRBK22.13875416
9PINK11.98762505
10ZAK1.85517390
11WNK41.79111128
12RIPK41.70780791
13CDK81.65618580
14BMPR1B1.40108985
15ERBB31.32512063
16BMPR21.32296769
17EPHA31.31488498
18MAP3K141.27651517
19NME11.26922202
20TRIM281.25772744
21STK38L1.24559191
22GRK11.22295571
23TESK21.20356394
24IKBKE1.15953521
25RPS6KA41.08507968
26MUSK1.08350686
27WNK31.07927942
28TBK11.05337421
29CAMKK21.02576058
30MAPKAPK31.01335182
31PASK0.99465891
32MAP4K10.98540587
33NUAK10.97631247
34SYK0.96966423
35IKBKB0.96853283
36TNK20.94800456
37JAK10.93684071
38MST40.92951904
39KDR0.92516553
40OXSR10.92495459
41MAP3K40.92151759
42MAPK130.86840103
43PIK3CA0.86484852
44ZAP700.85101300
45ITK0.83977915
46PIM10.83638209
47TIE10.78445643
48KIT0.76504592
49MAP2K60.75530206
50LCK0.74745050
51SRPK10.71794253
52MATK0.71185428
53GRK70.70750877
54IRAK30.70659171
55TEC0.69043917
56RPS6KA50.64902527
57PRKCE0.63524702
58LYN0.62096965
59FES0.59728288
60BCR0.59471653
61MAPK70.59064574
62INSRR0.54086662
63CDK30.53572241
64PHKG20.52862469
65PHKG10.52862469
66STK390.52483093
67BTK0.51732676
68TRPM70.47583181
69BCKDK0.45272001
70DAPK20.45240761
71PTK2B0.44684796
72IGF1R0.42208042
73LIMK10.40198612
74EIF2AK20.37281690
75PRKCQ0.36291528
76CSF1R0.34641368
77CDK190.33992677
78PLK20.33845307
79CSK0.33416857
80NEK10.31817116
81CLK10.31502091
82MAP2K10.31276658
83CAMK10.31207522
84ABL10.30386193
85TGFBR10.29143856
86RPS6KA60.27787916
87CAMKK10.27018610
88JAK30.26566154
89ERBB20.25629214
90NLK0.25195739
91PRKACA0.24755581
92ADRBK10.24734367
93VRK10.24630962
94MAP3K120.24046600
95PRKCG0.22937853
96MAPK150.22031307
97CSNK1A10.21975347
98BLK0.21959106
99OBSCN0.19738545
100EGFR0.18940439

Predicted pathways (KEGG)

RankGene SetZ-score
1Intestinal immune network for IgA production_Homo sapiens_hsa046723.48968992
2Primary immunodeficiency_Homo sapiens_hsa053403.42756454
3Asthma_Homo sapiens_hsa053102.88360882
4Allograft rejection_Homo sapiens_hsa053302.64702599
5Autoimmune thyroid disease_Homo sapiens_hsa053202.43100252
6Graft-versus-host disease_Homo sapiens_hsa053322.37759009
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.35232522
8Type I diabetes mellitus_Homo sapiens_hsa049402.34695105
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.32707647
10Phototransduction_Homo sapiens_hsa047442.30950223
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.28980999
12Oxidative phosphorylation_Homo sapiens_hsa001901.83920379
13Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.78605129
14Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.78522468
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.72417475
16Nicotine addiction_Homo sapiens_hsa050331.70629849
17Regulation of autophagy_Homo sapiens_hsa041401.69429263
18Arachidonic acid metabolism_Homo sapiens_hsa005901.66984075
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64043872
20Basal transcription factors_Homo sapiens_hsa030221.62259266
21Nitrogen metabolism_Homo sapiens_hsa009101.59321369
22Rheumatoid arthritis_Homo sapiens_hsa053231.56782899
23Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.50874379
24Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.47439202
25RNA degradation_Homo sapiens_hsa030181.45623670
26Linoleic acid metabolism_Homo sapiens_hsa005911.45335677
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.36551443
28Chemical carcinogenesis_Homo sapiens_hsa052041.36208449
29Protein export_Homo sapiens_hsa030601.35147711
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.29176895
31T cell receptor signaling pathway_Homo sapiens_hsa046601.27772539
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.27564865
33Selenocompound metabolism_Homo sapiens_hsa004501.25275300
34Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.24655499
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.24046909
36NF-kappa B signaling pathway_Homo sapiens_hsa040641.23417055
37Morphine addiction_Homo sapiens_hsa050321.23387042
38Parkinsons disease_Homo sapiens_hsa050121.20630671
39Primary bile acid biosynthesis_Homo sapiens_hsa001201.18165220
40Antigen processing and presentation_Homo sapiens_hsa046121.17983657
41Taste transduction_Homo sapiens_hsa047421.16923667
42Collecting duct acid secretion_Homo sapiens_hsa049661.15436662
43Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.06307907
44SNARE interactions in vesicular transport_Homo sapiens_hsa041301.05281484
45Hematopoietic cell lineage_Homo sapiens_hsa046401.03518385
46RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.02024613
47Cardiac muscle contraction_Homo sapiens_hsa042600.90398338
48Olfactory transduction_Homo sapiens_hsa047400.89161766
49Proteasome_Homo sapiens_hsa030500.88961253
50Fanconi anemia pathway_Homo sapiens_hsa034600.88273943
51Peroxisome_Homo sapiens_hsa041460.88188926
52Sulfur metabolism_Homo sapiens_hsa009200.88098489
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.86573354
54Butanoate metabolism_Homo sapiens_hsa006500.84735678
55RNA polymerase_Homo sapiens_hsa030200.84541443
56Alzheimers disease_Homo sapiens_hsa050100.82904773
57Leishmaniasis_Homo sapiens_hsa051400.81546857
58Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.81253141
59Homologous recombination_Homo sapiens_hsa034400.79736963
60GABAergic synapse_Homo sapiens_hsa047270.77281328
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75964267
62Circadian entrainment_Homo sapiens_hsa047130.75845514
63Circadian rhythm_Homo sapiens_hsa047100.72889719
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72883770
65Amphetamine addiction_Homo sapiens_hsa050310.72202385
66Caffeine metabolism_Homo sapiens_hsa002320.70693687
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.68526790
68Huntingtons disease_Homo sapiens_hsa050160.67822754
69Ether lipid metabolism_Homo sapiens_hsa005650.67224416
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65694359
71Purine metabolism_Homo sapiens_hsa002300.65662356
72Tryptophan metabolism_Homo sapiens_hsa003800.65201051
73Renin secretion_Homo sapiens_hsa049240.63257704
74Salivary secretion_Homo sapiens_hsa049700.59798755
75Viral myocarditis_Homo sapiens_hsa054160.57012056
76Serotonergic synapse_Homo sapiens_hsa047260.55310966
77ABC transporters_Homo sapiens_hsa020100.54327124
78Glutathione metabolism_Homo sapiens_hsa004800.53949806
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.53834155
80Insulin secretion_Homo sapiens_hsa049110.53819674
81Measles_Homo sapiens_hsa051620.52276645
82Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.52201172
83Retinol metabolism_Homo sapiens_hsa008300.51728923
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.49466899
85Malaria_Homo sapiens_hsa051440.47403007
86Cyanoamino acid metabolism_Homo sapiens_hsa004600.46761580
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.45331758
88Calcium signaling pathway_Homo sapiens_hsa040200.43838927
89Shigellosis_Homo sapiens_hsa051310.42888188
90TNF signaling pathway_Homo sapiens_hsa046680.42275585
91Herpes simplex infection_Homo sapiens_hsa051680.41010503
92Systemic lupus erythematosus_Homo sapiens_hsa053220.39735131
93Spliceosome_Homo sapiens_hsa030400.39613996
94Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39565471
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39106028
96Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37935165
97Toll-like receptor signaling pathway_Homo sapiens_hsa046200.37120973
98African trypanosomiasis_Homo sapiens_hsa051430.36601334
99Staphylococcus aureus infection_Homo sapiens_hsa051500.36549430
100Legionellosis_Homo sapiens_hsa051340.34248198

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »