CENPI

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)5.64693018
2protein localization to kinetochore (GO:0034501)5.48611615
3mitotic metaphase plate congression (GO:0007080)5.33652424
4mitotic sister chromatid segregation (GO:0000070)5.08189203
5kinetochore assembly (GO:0051382)5.06203130
6* CENP-A containing nucleosome assembly (GO:0034080)4.93884850
7attachment of spindle microtubules to kinetochore (GO:0008608)4.90143379
8protein localization to chromosome, centromeric region (GO:0071459)4.89402650
9* chromatin remodeling at centromere (GO:0031055)4.80489422
10sister chromatid segregation (GO:0000819)4.78754512
11metaphase plate congression (GO:0051310)4.73086334
12meiotic chromosome segregation (GO:0045132)4.69301563
13DNA replication initiation (GO:0006270)4.59683645
14mitotic chromosome condensation (GO:0007076)4.57860461
15telomere maintenance via semi-conservative replication (GO:0032201)4.57028598
16DNA strand elongation involved in DNA replication (GO:0006271)4.49332219
17microtubule depolymerization (GO:0007019)4.42417507
18establishment of chromosome localization (GO:0051303)4.40598549
19mitotic recombination (GO:0006312)4.37695452
20* DNA replication-independent nucleosome organization (GO:0034724)4.35023574
21* DNA replication-independent nucleosome assembly (GO:0006336)4.35023574
22telomere maintenance via recombination (GO:0000722)4.34176189
23DNA strand elongation (GO:0022616)4.32715777
24regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.30505215
25regulation of spindle organization (GO:0090224)4.19328098
26DNA unwinding involved in DNA replication (GO:0006268)4.18391436
27DNA replication checkpoint (GO:0000076)4.11732169
28nuclear pore organization (GO:0006999)4.01085488
29spindle checkpoint (GO:0031577)3.99846100
30mitotic nuclear envelope disassembly (GO:0007077)3.98046979
31* histone exchange (GO:0043486)3.95220088
32regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.91728363
33telomere maintenance via telomere lengthening (GO:0010833)3.88193848
34regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.87612494
35establishment of integrated proviral latency (GO:0075713)3.86538689
36protein K6-linked ubiquitination (GO:0085020)3.82059976
37nuclear pore complex assembly (GO:0051292)3.78072393
38regulation of mitotic spindle organization (GO:0060236)3.77301726
39mitotic sister chromatid cohesion (GO:0007064)3.76219568
40chromosome segregation (GO:0007059)3.75204343
41spindle assembly checkpoint (GO:0071173)3.74297901
42response to X-ray (GO:0010165)3.70948459
43positive regulation of chromosome segregation (GO:0051984)3.70684292
44DNA replication-dependent nucleosome organization (GO:0034723)3.69989372
45DNA replication-dependent nucleosome assembly (GO:0006335)3.69989372
46non-recombinational repair (GO:0000726)3.68699557
47double-strand break repair via nonhomologous end joining (GO:0006303)3.68699557
48regulation of chromosome segregation (GO:0051983)3.65710990
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.63676077
50regulation of double-strand break repair via homologous recombination (GO:0010569)3.62681168
51membrane disassembly (GO:0030397)3.62465054
52nuclear envelope disassembly (GO:0051081)3.62465054
53negative regulation of chromosome segregation (GO:0051985)3.62335231
54regulation of mitotic metaphase/anaphase transition (GO:0030071)3.61582578
55negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.60622063
56negative regulation of sister chromatid segregation (GO:0033046)3.60622063
57negative regulation of mitotic sister chromatid separation (GO:2000816)3.60622063
58negative regulation of mitotic sister chromatid segregation (GO:0033048)3.60622063
59protein localization to chromosome (GO:0034502)3.56807872
60maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.55544416
61negative regulation of DNA-dependent DNA replication (GO:2000104)3.55246185
62mitotic spindle checkpoint (GO:0071174)3.55059094
63mitotic spindle assembly checkpoint (GO:0007094)3.53933175
64regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.53590557
65regulation of nuclear cell cycle DNA replication (GO:0033262)3.51759968
66negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.50307697
67regulation of DNA endoreduplication (GO:0032875)3.48623786
68positive regulation of mitotic sister chromatid separation (GO:1901970)3.45615534
69positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.45615534
70positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.45615534
71regulation of mitotic sister chromatid separation (GO:0010965)3.45361457
72regulation of mitotic sister chromatid segregation (GO:0033047)3.45361457
73regulation of sister chromatid segregation (GO:0033045)3.45361457
74centrosome duplication (GO:0051298)3.41230341
75regulation of centrosome cycle (GO:0046605)3.38304361
76telomere maintenance (GO:0000723)3.37065851
77negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.34869475
78telomere organization (GO:0032200)3.33575817
79nucleobase biosynthetic process (GO:0046112)3.28447492
80* chromatin assembly or disassembly (GO:0006333)3.26465282
81DNA strand renaturation (GO:0000733)3.23817600
82replication fork processing (GO:0031297)3.23322495
83cytoplasmic mRNA processing body assembly (GO:0033962)3.22786879
84regulation of centrosome duplication (GO:0010824)3.22197771
85DNA ligation (GO:0006266)3.22039515
86mismatch repair (GO:0006298)3.21008675
87DNA topological change (GO:0006265)3.20110493
88IMP biosynthetic process (GO:0006188)3.15181564
89translesion synthesis (GO:0019985)3.13902451
90DNA double-strand break processing (GO:0000729)3.10869619
91ventricular cardiac muscle cell development (GO:0055015)3.09862512
92DNA geometric change (GO:0032392)3.09604060
93regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.09079960
94regulation of mitotic spindle checkpoint (GO:1903504)3.09079960
95purine nucleobase biosynthetic process (GO:0009113)3.09059822
96somatic hypermutation of immunoglobulin genes (GO:0016446)3.07980810
97somatic diversification of immune receptors via somatic mutation (GO:0002566)3.07980810
98chromosome condensation (GO:0030261)3.07951113
99DNA duplex unwinding (GO:0032508)3.05935648
100pore complex assembly (GO:0046931)3.05917783
101regulation of centriole replication (GO:0046599)3.05516711
102* mitotic cell cycle (GO:0000278)3.05186829
103postreplication repair (GO:0006301)3.04538769
104DNA packaging (GO:0006323)3.01179025
105spindle assembly (GO:0051225)2.99947955
106centriole replication (GO:0007099)2.99844234
107centrosome organization (GO:0051297)2.99479810
108regulation of sister chromatid cohesion (GO:0007063)2.98283620
109DNA conformation change (GO:0071103)2.96118226
110regulation of double-strand break repair (GO:2000779)2.94709860
111* ATP-dependent chromatin remodeling (GO:0043044)2.93127733
112DNA synthesis involved in DNA repair (GO:0000731)2.92987200
113histone-serine phosphorylation (GO:0035404)2.92659469
114positive regulation of DNA-dependent DNA replication (GO:2000105)2.88720026
115mitotic G2/M transition checkpoint (GO:0044818)2.87625713
116negative regulation of mitosis (GO:0045839)2.83786455
117* chromosome organization (GO:0051276)2.83085956

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.86702711
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.29858814
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.27522123
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.43662603
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.31948213
6MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.71071924
7AR_21909140_ChIP-Seq_LNCAP_Human2.66236257
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.57260645
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.43682371
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.39896696
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.38485814
12* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.34912623
13MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.29165921
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.26798900
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26774227
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.21874049
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.19570342
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.16044462
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.14801013
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.12341484
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05562944
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.00517828
23E2F7_22180533_ChIP-Seq_HELA_Human11.1596079
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.96514531
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.94831520
26VDR_23849224_ChIP-Seq_CD4+_Human1.94528306
27ELK1_19687146_ChIP-ChIP_HELA_Human1.91456967
28TP63_19390658_ChIP-ChIP_HaCaT_Human1.91151694
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81156286
30EGR1_19374776_ChIP-ChIP_THP-1_Human1.80446419
31FOXP3_21729870_ChIP-Seq_TREG_Human1.78070497
32YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71540311
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.71001692
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.69936987
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69566487
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68362594
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.64988127
38XRN2_22483619_ChIP-Seq_HELA_Human1.63125901
39DCP1A_22483619_ChIP-Seq_HELA_Human1.59973395
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57877363
41VDR_22108803_ChIP-Seq_LS180_Human1.55456251
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.51542221
43E2F1_18555785_ChIP-Seq_MESCs_Mouse1.51285984
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49991714
45TTF2_22483619_ChIP-Seq_HELA_Human1.49655351
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.47151218
47E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40102643
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.39575494
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.38948729
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.38479111
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.36016065
52PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32475498
53ZNF274_21170338_ChIP-Seq_K562_Hela1.28637026
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26766820
55POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.26414601
56GABP_19822575_ChIP-Seq_HepG2_Human1.24284968
57CIITA_25753668_ChIP-Seq_RAJI_Human1.19149814
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.15984311
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13583203
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11748319
61EWS_26573619_Chip-Seq_HEK293_Human1.10899106
62E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10722578
63SRF_21415370_ChIP-Seq_HL-1_Mouse1.09997016
64YY1_21170310_ChIP-Seq_MESCs_Mouse1.09495954
65KDM5A_27292631_Chip-Seq_BREAST_Human1.08310663
66MYC_18940864_ChIP-ChIP_HL60_Human1.07644131
67FUS_26573619_Chip-Seq_HEK293_Human1.05807057
68IRF1_19129219_ChIP-ChIP_H3396_Human1.05382548
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.03530006
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.02234166
71* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00603463
72ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00258535
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99891110
74TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.99320290
75POU3F2_20337985_ChIP-ChIP_501MEL_Human0.98664370
76IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.97774207
77ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97656240
78POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97467211
79SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96264597
80ZFX_18555785_ChIP-Seq_MESCs_Mouse0.91652336
81TAF15_26573619_Chip-Seq_HEK293_Human0.90066908
82SOX2_16153702_ChIP-ChIP_HESCs_Human0.87627752
83FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.87032173
84HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.83605962
85SPI1_23547873_ChIP-Seq_NB4_Human0.80620863
86BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.79535665
87FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.78740168
88GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78084643
89SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.77686664
90TFEB_21752829_ChIP-Seq_HELA_Human0.77671583
91PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77465241
92IRF8_21731497_ChIP-ChIP_J774_Mouse0.76993032
93ESR1_15608294_ChIP-ChIP_MCF-7_Human0.75948319
94SOX9_26525672_Chip-Seq_HEART_Mouse0.74721931
95CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.74709740
96NANOG_16153702_ChIP-ChIP_HESCs_Human0.74669736
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.74657300
98IGF1R_20145208_ChIP-Seq_DFB_Human0.73778076
99FLI1_27457419_Chip-Seq_LIVER_Mouse0.73179616
100NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.72713148
101CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.72481480
102RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.69609381
103SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.68862414
104RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.68684223
105CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.67891894
106* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.67001264
107TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.66902607
108PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.66679511
109PCGF2_27294783_Chip-Seq_NPCs_Mouse0.65901062
110CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.65503522
111SOX17_20123909_ChIP-Seq_XEN_Mouse0.65269366
112BRD4_25478319_ChIP-Seq_HGPS_Human0.65078472
113CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.63657069
114ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.63438607
115CTBP2_25329375_ChIP-Seq_LNCAP_Human0.63100787
116FOXM1_26456572_ChIP-Seq_MCF-7_Human0.61850179
117PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.60932256
118WT1_19549856_ChIP-ChIP_CCG9911_Human0.58731399
119P300_19829295_ChIP-Seq_ESCs_Human0.57669926
120KLF4_18555785_ChIP-Seq_MESCs_Mouse0.56711645
121TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.56587218
122NANOG_21062744_ChIP-ChIP_HESCs_Human0.55133478

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.24323830
2MP0003693_abnormal_embryo_hatching5.14790016
3MP0003111_abnormal_nucleus_morphology4.95820939
4MP0008057_abnormal_DNA_replication4.70364204
5MP0003077_abnormal_cell_cycle3.99882564
6MP0004957_abnormal_blastocyst_morpholog3.61266502
7MP0008058_abnormal_DNA_repair3.56459749
8MP0002396_abnormal_hematopoietic_system2.98983674
9MP0008007_abnormal_cellular_replicative2.92934036
10MP0008877_abnormal_DNA_methylation2.62702335
11MP0008932_abnormal_embryonic_tissue2.54451864
12MP0003786_premature_aging2.09862786
13MP0003123_paternal_imprinting1.96810216
14MP0000350_abnormal_cell_proliferation1.94043399
15MP0010307_abnormal_tumor_latency1.93951795
16MP0001188_hyperpigmentation1.90946788
17MP0000490_abnormal_crypts_of1.76810326
18MP0003121_genomic_imprinting1.68963208
19MP0003136_yellow_coat_color1.65354861
20MP0006292_abnormal_olfactory_placode1.57657523
21MP0001730_embryonic_growth_arrest1.51239103
22MP0004808_abnormal_hematopoietic_stem1.45810249
23MP0003718_maternal_effect1.44229212
24MP0001672_abnormal_embryogenesis/_devel1.42078875
25MP0005380_embryogenesis_phenotype1.42078875
26MP0000569_abnormal_digit_pigmentation1.40854323
27MP0003941_abnormal_skin_development1.39798726
28MP0003806_abnormal_nucleotide_metabolis1.33474732
29MP0003787_abnormal_imprinting1.30542438
30MP0002102_abnormal_ear_morphology1.30349841
31MP0004147_increased_porphyrin_level1.28215422
32MP0001697_abnormal_embryo_size1.28213005
33MP0002210_abnormal_sex_determination1.27189028
34MP0000313_abnormal_cell_death1.24256255
35MP0002019_abnormal_tumor_incidence1.22149463
36MP0003984_embryonic_growth_retardation1.21694158
37MP0006035_abnormal_mitochondrial_morpho1.21368199
38MP0002736_abnormal_nociception_after1.21313772
39MP0002085_abnormal_embryonic_tissue1.21170130
40MP0006072_abnormal_retinal_apoptosis1.20647034
41MP0000566_synostosis1.19691562
42MP0002088_abnormal_embryonic_growth/wei1.17704291
43MP0009697_abnormal_copulation1.16407154
44MP0003937_abnormal_limbs/digits/tail_de1.15186857
45MP0000358_abnormal_cell_content/1.15126676
46MP0009672_abnormal_birth_weight1.15012743
47MP0002234_abnormal_pharynx_morphology1.14945826
48MP0002080_prenatal_lethality1.12306753
49MP0000427_abnormal_hair_cycle1.10965842
50MP0003890_abnormal_embryonic-extraembry1.10213265
51MP0000015_abnormal_ear_pigmentation1.08420055
52MP0000428_abnormal_craniofacial_morphol1.08151917
53MP0004233_abnormal_muscle_weight1.08086947
54MP0003119_abnormal_digestive_system1.07047966
55MP0002877_abnormal_melanocyte_morpholog1.06645347
56MP0003950_abnormal_plasma_membrane1.06274061
57MP0002086_abnormal_extraembryonic_tissu1.06108606
58MP0003315_abnormal_perineum_morphology1.06106496
59MP0003935_abnormal_craniofacial_develop1.05460834
60MP0002697_abnormal_eye_size1.03829989
61MP0003943_abnormal_hepatobiliary_system1.03266487
62MP0005395_other_phenotype1.02284654
63MP0001545_abnormal_hematopoietic_system1.01986048
64MP0005397_hematopoietic_system_phenotyp1.01986048
65MP0002084_abnormal_developmental_patter1.01792489
66MP0000537_abnormal_urethra_morphology1.00751124
67MP0001145_abnormal_male_reproductive1.00713686
68MP0000703_abnormal_thymus_morphology1.00657099
69MP0010030_abnormal_orbit_morphology1.00439581
70MP0004197_abnormal_fetal_growth/weight/0.99665710
71MP0002398_abnormal_bone_marrow0.98840469
72MP0001293_anophthalmia0.98243299
73MP0003252_abnormal_bile_duct0.97601288
74MP0002095_abnormal_skin_pigmentation0.97074241
75MP0001119_abnormal_female_reproductive0.96028728
76MP0002233_abnormal_nose_morphology0.95530032
77MP0001929_abnormal_gametogenesis0.94494705
78MP0000647_abnormal_sebaceous_gland0.93736203
79MP0003567_abnormal_fetal_cardiomyocyte0.93237747
80MP0002938_white_spotting0.92491114
81MP0010352_gastrointestinal_tract_polyps0.91783984
82MP0000653_abnormal_sex_gland0.88714891
83MP0002163_abnormal_gland_morphology0.87426488
84MP0002722_abnormal_immune_system0.86932962
85MP0002132_abnormal_respiratory_system0.85779212
86MP0000689_abnormal_spleen_morphology0.85572559
87MP0000372_irregular_coat_pigmentation0.85057767
88MP0003763_abnormal_thymus_physiology0.83252178
89MP0003385_abnormal_body_wall0.82463045
90MP0000858_altered_metastatic_potential0.82207547
91MP0005174_abnormal_tail_pigmentation0.81356274
92MP0009053_abnormal_anal_canal0.81232553
93MP0000383_abnormal_hair_follicle0.80126396
94MP0005171_absent_coat_pigmentation0.79900924
95MP0001661_extended_life_span0.79085100
96MP0001299_abnormal_eye_distance/0.79008756
97MP0002751_abnormal_autonomic_nervous0.78994527
98MP0009333_abnormal_splenocyte_physiolog0.78697929
99MP0003861_abnormal_nervous_system0.78436597
100MP0002277_abnormal_respiratory_mucosa0.74250021
101MP0005391_vision/eye_phenotype0.74150640
102MP0005623_abnormal_meninges_morphology0.73806980
103MP0005621_abnormal_cell_physiology0.73026200
104MP0003699_abnormal_female_reproductive0.72854368
105MP0005253_abnormal_eye_physiology0.72737055
106MP0001186_pigmentation_phenotype0.72640233
107MP0004133_heterotaxia0.72503590
108MP0003186_abnormal_redox_activity0.72319973
109MP0002160_abnormal_reproductive_system0.72001975
110MP0005408_hypopigmentation0.71191689
111MP0002092_abnormal_eye_morphology0.70101961
112MP0008995_early_reproductive_senescence0.69708131
113MP0002429_abnormal_blood_cell0.69170060
114MP0000432_abnormal_head_morphology0.69114976
115MP0005384_cellular_phenotype0.67693724
116MP0002075_abnormal_coat/hair_pigmentati0.66869092
117MP0009250_abnormal_appendicular_skeleto0.66701284
118MP0002111_abnormal_tail_morphology0.66430439
119MP0001286_abnormal_eye_development0.66201632
120MP0005076_abnormal_cell_differentiation0.65630788
121MP0000049_abnormal_middle_ear0.65281540
122MP0000371_diluted_coat_color0.65012416
123MP0002161_abnormal_fertility/fecundity0.64755698
124MP0001529_abnormal_vocalization0.64132341
125MP0009703_decreased_birth_body0.63939565
126MP0002177_abnormal_outer_ear0.63556852
127MP0005389_reproductive_system_phenotype0.63384027
128MP0008770_decreased_survivor_rate0.63134715
129MP0003755_abnormal_palate_morphology0.61659936
130MP0004381_abnormal_hair_follicle0.61278517
131MP0000716_abnormal_immune_system0.60847134
132MP0001835_abnormal_antigen_presentation0.60839550
133MP0003936_abnormal_reproductive_system0.60377579
134MP0005075_abnormal_melanosome_morpholog0.60057574
135MP0001800_abnormal_humoral_immune0.57734990
136MP0001346_abnormal_lacrimal_gland0.56597184
137MP0003938_abnormal_ear_development0.56202714
138MP0002420_abnormal_adaptive_immunity0.55384195
139MP0001819_abnormal_immune_cell0.54542958
140MP0003698_abnormal_male_reproductive0.53978507
141MP0002452_abnormal_antigen_presenting0.53742016

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)6.72667287
2Chromsome breakage (HP:0040012)6.68315523
3Abnormality of chromosome stability (HP:0003220)4.41568492
4Birth length less than 3rd percentile (HP:0003561)4.34889461
5Abnormality of the preputium (HP:0100587)4.18338906
6Meckel diverticulum (HP:0002245)4.14984604
7Duplicated collecting system (HP:0000081)4.11613035
8Aplasia/Hypoplasia of the uvula (HP:0010293)3.98611611
9Abnormality of the ileum (HP:0001549)3.97842737
10Abnormality of the renal collecting system (HP:0004742)3.68503466
11Small intestinal stenosis (HP:0012848)3.42407769
12Duodenal stenosis (HP:0100867)3.42407769
13Reticulocytopenia (HP:0001896)3.40724546
14Ectopic kidney (HP:0000086)3.22998601
15Impulsivity (HP:0100710)3.10317312
16Nephroblastoma (Wilms tumor) (HP:0002667)3.06701432
17Cortical dysplasia (HP:0002539)3.06528096
18Myelodysplasia (HP:0002863)2.99482916
19Patellar aplasia (HP:0006443)2.96690488
20Sloping forehead (HP:0000340)2.96617266
21Clubbing of toes (HP:0100760)2.92308799
22Absent radius (HP:0003974)2.91761425
23Embryonal renal neoplasm (HP:0011794)2.88223488
24Breast hypoplasia (HP:0003187)2.85705392
25Bone marrow hypocellularity (HP:0005528)2.83494718
26Abnormality of DNA repair (HP:0003254)2.82081211
27Volvulus (HP:0002580)2.77345985
28Absent forearm bone (HP:0003953)2.74463676
29Aplasia involving forearm bones (HP:0009822)2.74463676
30Abnormality of the duodenum (HP:0002246)2.73490228
31Aplasia/Hypoplasia of the patella (HP:0006498)2.70517057
32Dysmetric saccades (HP:0000641)2.63829520
33Ependymoma (HP:0002888)2.57239817
34Abnormality of the carotid arteries (HP:0005344)2.56770824
35Selective tooth agenesis (HP:0001592)2.54956514
36Abnormality of the labia minora (HP:0012880)2.53755451
37Prostate neoplasm (HP:0100787)2.53444028
38Glioma (HP:0009733)2.49869745
39Abnormal lung lobation (HP:0002101)2.47167525
40Pendular nystagmus (HP:0012043)2.46809879
41Astrocytoma (HP:0009592)2.46547264
42Abnormality of the astrocytes (HP:0100707)2.46547264
43Triphalangeal thumb (HP:0001199)2.39025876
44Absent thumb (HP:0009777)2.37435582
45Premature graying of hair (HP:0002216)2.37020467
46Aplastic anemia (HP:0001915)2.34434969
4711 pairs of ribs (HP:0000878)2.33585779
48Medulloblastoma (HP:0002885)2.30710597
49Short thumb (HP:0009778)2.29414166
50Abnormal number of incisors (HP:0011064)2.28885929
51Genetic anticipation (HP:0003743)2.26614235
52Supernumerary spleens (HP:0009799)2.25027172
53Agnosia (HP:0010524)2.24289094
54Tracheoesophageal fistula (HP:0002575)2.12274232
55Oral leukoplakia (HP:0002745)2.11963305
56Rough bone trabeculation (HP:0100670)2.06055742
57Ureteral duplication (HP:0000073)2.05157022
58Horseshoe kidney (HP:0000085)2.03401223
59Hypoplastic pelvis (HP:0008839)2.02925330
60Small hand (HP:0200055)2.02851201
61Hypoplasia of the capital femoral epiphysis (HP:0003090)2.02098089
62Short middle phalanx of the 5th finger (HP:0004220)2.00917453
63Neoplasm of the colon (HP:0100273)1.95772735
64High pitched voice (HP:0001620)1.94572326
65Gaze-evoked nystagmus (HP:0000640)1.94137446
66Postnatal microcephaly (HP:0005484)1.93679963
67Multiple enchondromatosis (HP:0005701)1.90775386
68Duplication of thumb phalanx (HP:0009942)1.90462935
69Cafe-au-lait spot (HP:0000957)1.90294063
70Pancreatic fibrosis (HP:0100732)1.90027274
71Neoplasm of the adrenal cortex (HP:0100641)1.88968028
72Increased nuchal translucency (HP:0010880)1.88448951
73Deep philtrum (HP:0002002)1.85032370
74High anterior hairline (HP:0009890)1.84521987
75Aplasia/Hypoplasia of the earlobes (HP:0009906)1.83878157
76Missing ribs (HP:0000921)1.82449014
77Overlapping toe (HP:0001845)1.80264661
78Aplasia/Hypoplasia of the sacrum (HP:0008517)1.79401615
79Embryonal neoplasm (HP:0002898)1.78707573
80Lymphoma (HP:0002665)1.78256171
81Abnormal umbilical cord blood vessels (HP:0011403)1.78166682
82Single umbilical artery (HP:0001195)1.78166682
83Abnormality of the fetal cardiovascular system (HP:0010948)1.78166682
84Aplasia/Hypoplasia of the sternum (HP:0006714)1.77080092
85Arteriovenous malformation (HP:0100026)1.74893493
86Leukopenia (HP:0001882)1.74430262
87Pancreatic cysts (HP:0001737)1.73855370
88Acute myeloid leukemia (HP:0004808)1.72873476
89Pallor (HP:0000980)1.72354536
90Abnormality of the pons (HP:0007361)1.70881557
91Abnormal auditory evoked potentials (HP:0006958)1.70076753
92Preaxial hand polydactyly (HP:0001177)1.69960226
93Abnormality of the heme biosynthetic pathway (HP:0010472)1.69850329
94Carpal bone hypoplasia (HP:0001498)1.69669038
95Abnormal number of erythroid precursors (HP:0012131)1.69565218
96Abdominal situs inversus (HP:0003363)1.69101517
97Abnormality of abdominal situs (HP:0011620)1.69101517
98Dandy-Walker malformation (HP:0001305)1.68342792
99Abnormality of the incisor (HP:0000676)1.67554839
100Short 4th metacarpal (HP:0010044)1.67353310
101Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.67353310
102Squamous cell carcinoma (HP:0002860)1.66913735
103Cellular immunodeficiency (HP:0005374)1.66147763
104Proximal placement of thumb (HP:0009623)1.66067034
105Abnormal trabecular bone morphology (HP:0100671)1.66066744
106Oligohydramnios (HP:0001562)1.65235831
107Hypoplasia of the pons (HP:0012110)1.65087583
108True hermaphroditism (HP:0010459)1.63993816
109Deviation of the thumb (HP:0009603)1.63896207
110Rhabdomyosarcoma (HP:0002859)1.63049921
111Atresia of the external auditory canal (HP:0000413)1.62369808
112Abnormality of the prostate (HP:0008775)1.61444197
113Action tremor (HP:0002345)1.60991986
114Abnormality of cells of the erythroid lineage (HP:0012130)1.60767914
115Facial cleft (HP:0002006)1.60308657
116Optic nerve coloboma (HP:0000588)1.60239328
117Cleft eyelid (HP:0000625)1.59965150
118Acute lymphatic leukemia (HP:0006721)1.59652017
119Neoplasm of the pancreas (HP:0002894)1.59569506
120Colon cancer (HP:0003003)1.59165820
121Abnormal spermatogenesis (HP:0008669)1.58261555
122Abnormality of chromosome segregation (HP:0002916)1.57981575
123Prominent nose (HP:0000448)1.57808397
124Pancytopenia (HP:0001876)1.57656058
125Oculomotor apraxia (HP:0000657)1.56736105
126Bilateral microphthalmos (HP:0007633)1.56596219
127Rib fusion (HP:0000902)1.56433487
128Degeneration of anterior horn cells (HP:0002398)1.54740553
129Abnormality of the anterior horn cell (HP:0006802)1.54740553
130Microtia (HP:0008551)1.54388332
131Facial hemangioma (HP:0000329)1.54206219
132Biliary tract neoplasm (HP:0100574)1.54103128
133Choanal atresia (HP:0000453)1.53324037
134Intestinal atresia (HP:0011100)1.51577781
135Increased serum pyruvate (HP:0003542)1.50927964
136Astigmatism (HP:0000483)1.50732201
137Long clavicles (HP:0000890)1.50521446
138Bifid tongue (HP:0010297)1.49984909
139Abnormality of the umbilical cord (HP:0010881)1.48577858
140Sclerocornea (HP:0000647)1.48354856
141Abnormality of glycolysis (HP:0004366)1.47895475
142Neoplasm of striated muscle (HP:0009728)1.47155142
143Holoprosencephaly (HP:0001360)1.45705248

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.71854963
2CDC74.37081695
3WEE14.32981558
4BRSK23.27596100
5SRPK13.17338708
6NEK22.99049291
7TTK2.83876601
8EIF2AK12.71575949
9PLK12.29465436
10STK162.25449227
11BRSK12.18895356
12CCNB12.14894989
13ZAK2.07806773
14PLK42.07430922
15MKNK12.04522833
16AURKB2.02535786
17VRK12.02159615
18PLK31.96499185
19ATR1.88218624
20EIF2AK21.87847851
21VRK21.87743546
22MKNK21.84115881
23TAF11.82211029
24CHEK21.81382742
25TLK11.76893544
26CDK191.70038211
27ACVR1B1.68523471
28NEK11.62174878
29STK41.60819624
30TSSK61.59253488
31CDK71.58409940
32CDK121.46100086
33STK101.41988147
34TRIM281.35428292
35EIF2AK31.34047364
36BCR1.33273772
37FRK1.29715146
38OXSR11.26903212
39CHEK11.25894724
40CDK41.25077624
41NME21.24387786
42BRD41.23938464
43AURKA1.19088716
44CLK11.15486520
45MAP3K81.10075574
46YES11.09940427
47ATM1.09704708
48MELK1.04149683
49DYRK31.00755901
50RPS6KA41.00476036
51ERBB40.98990798
52RPS6KB20.98513266
53PASK0.98009499
54STK30.90082459
55MST1R0.88502579
56CDK80.84655168
57NUAK10.83748097
58CDK60.79870036
59MET0.79756286
60AKT30.79080505
61WNK30.79019231
62CDK20.78161582
63PBK0.76825695
64TNIK0.76336020
65EPHA20.76219472
66CDK10.75899243
67ALK0.73839530
68MARK30.70259855
69PIM10.68136361
70TRPM70.65281231
71MST40.58367578
72CDK30.57926061
73SMG10.56986502
74CSNK2A10.56649562
75NEK90.55567863
76RPS6KA50.54307709
77TXK0.54193389
78BRAF0.52821781
79STK38L0.51806294
80CSNK1G10.50876948
81CASK0.50540030
82LATS10.49658180
83IRAK40.47795288
84CSNK2A20.46883589
85ERBB30.42220907
86TESK20.41979011
87BLK0.41274063
88PLK20.41047226
89EEF2K0.40321205
90TEC0.39881099
91KIT0.39035429
92STK390.39024488
93MAP3K140.38795081
94CSNK1G30.38194118
95PAK10.37290647
96CDK180.37242102
97CSF1R0.37131384
98TGFBR10.36154537
99PRKDC0.35874175
100CAMK1G0.34959611
101PDK20.34824630
102CSNK1A1L0.33922986
103FLT30.33781954
104MAPK140.32594630
105CDK150.32095632
106FGFR10.30775554
107LYN0.30746649
108MAP3K100.27988965
109SCYL20.27821717
110CSNK1E0.27273517
111BMPR1B0.27178593
112AKT20.26537031
113MAPKAPK50.25933156
114RPS6KB10.25231165
115AKT10.25212142
116NME10.25154695
117GRK10.24400236
118CDK140.23841131
119PRKCI0.20251067
120MAP3K60.19305725
121CDK90.18243829
122GSK3B0.17819291
123CHUK0.15726403
124PAK40.15617632
125MAPK10.14645227
126CSNK1D0.14432294
127PNCK0.11505485
128CDK11A0.11064383
129MAP4K10.10941167

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.95947478
2Mismatch repair_Homo sapiens_hsa034304.21160796
3Homologous recombination_Homo sapiens_hsa034403.71876345
4Fanconi anemia pathway_Homo sapiens_hsa034603.31564934
5Cell cycle_Homo sapiens_hsa041103.24494858
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.22905739
7Base excision repair_Homo sapiens_hsa034103.10526879
8Non-homologous end-joining_Homo sapiens_hsa034503.06286933
9Nucleotide excision repair_Homo sapiens_hsa034202.98389617
10Spliceosome_Homo sapiens_hsa030402.76049838
11RNA transport_Homo sapiens_hsa030132.65228895
12RNA polymerase_Homo sapiens_hsa030202.59911396
13One carbon pool by folate_Homo sapiens_hsa006702.50672633
14Proteasome_Homo sapiens_hsa030502.16712683
15Pyrimidine metabolism_Homo sapiens_hsa002402.15904239
16Ribosome_Homo sapiens_hsa030102.00314942
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.97592160
18p53 signaling pathway_Homo sapiens_hsa041151.93685270
19Basal transcription factors_Homo sapiens_hsa030221.90155611
20RNA degradation_Homo sapiens_hsa030181.83787771
21Cysteine and methionine metabolism_Homo sapiens_hsa002701.77130273
22Systemic lupus erythematosus_Homo sapiens_hsa053221.76480804
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.65659390
24mRNA surveillance pathway_Homo sapiens_hsa030151.63832024
25Selenocompound metabolism_Homo sapiens_hsa004501.50379367
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.36433865
27Steroid biosynthesis_Homo sapiens_hsa001001.30207300
28Propanoate metabolism_Homo sapiens_hsa006401.30112558
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26480776
30Purine metabolism_Homo sapiens_hsa002301.26124301
31Oocyte meiosis_Homo sapiens_hsa041141.17307298
32Herpes simplex infection_Homo sapiens_hsa051681.17036112
33Pyruvate metabolism_Homo sapiens_hsa006201.13745637
34Epstein-Barr virus infection_Homo sapiens_hsa051691.13574938
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.13539922
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.12881236
37Vitamin B6 metabolism_Homo sapiens_hsa007501.12008798
38Viral carcinogenesis_Homo sapiens_hsa052031.08790979
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.04424484
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99711002
41Biosynthesis of amino acids_Homo sapiens_hsa012300.98351993
42Primary bile acid biosynthesis_Homo sapiens_hsa001200.97966697
43Lysine degradation_Homo sapiens_hsa003100.97649887
44MicroRNAs in cancer_Homo sapiens_hsa052060.92312041
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90092040
46HTLV-I infection_Homo sapiens_hsa051660.83681621
47Primary immunodeficiency_Homo sapiens_hsa053400.83225548
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.82889361
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.81751850
50NF-kappa B signaling pathway_Homo sapiens_hsa040640.80109527
51Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79623719
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77737181
53Alcoholism_Homo sapiens_hsa050340.77431579
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76678865
55Measles_Homo sapiens_hsa051620.75754755
56Small cell lung cancer_Homo sapiens_hsa052220.75249320
57Antigen processing and presentation_Homo sapiens_hsa046120.68293763
58Hematopoietic cell lineage_Homo sapiens_hsa046400.68293750
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67199380
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66828681
61Glutathione metabolism_Homo sapiens_hsa004800.64229672
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63961162
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.63348316
64Legionellosis_Homo sapiens_hsa051340.59056508
65Carbon metabolism_Homo sapiens_hsa012000.57899182
66Hepatitis B_Homo sapiens_hsa051610.56490920
67Allograft rejection_Homo sapiens_hsa053300.56453892
68Autoimmune thyroid disease_Homo sapiens_hsa053200.56204364
69Apoptosis_Homo sapiens_hsa042100.55627371
70Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55273466
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54521156
72Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50872666
73Fatty acid elongation_Homo sapiens_hsa000620.50182989
74Influenza A_Homo sapiens_hsa051640.48466538
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47742698
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47243764
77Hedgehog signaling pathway_Homo sapiens_hsa043400.45763065
78Butanoate metabolism_Homo sapiens_hsa006500.45566960
79RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43841769
80Asthma_Homo sapiens_hsa053100.43081109
81TGF-beta signaling pathway_Homo sapiens_hsa043500.42452227
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.40895980
83Metabolic pathways_Homo sapiens_hsa011000.40297238
84Graft-versus-host disease_Homo sapiens_hsa053320.39621418
85Fatty acid metabolism_Homo sapiens_hsa012120.38906444
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38400421
87Colorectal cancer_Homo sapiens_hsa052100.37825112
88Melanoma_Homo sapiens_hsa052180.37433226
89Pentose phosphate pathway_Homo sapiens_hsa000300.34023902
90Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.33858420
91Fatty acid biosynthesis_Homo sapiens_hsa000610.33426800
92Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.33046890
93Leishmaniasis_Homo sapiens_hsa051400.31991932
94Malaria_Homo sapiens_hsa051440.31850349
95Prostate cancer_Homo sapiens_hsa052150.30518041
96Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28787608
97Shigellosis_Homo sapiens_hsa051310.28535026
98Pathways in cancer_Homo sapiens_hsa052000.27898320
99Basal cell carcinoma_Homo sapiens_hsa052170.27481486
100Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.27170290
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26331078
102Phototransduction_Homo sapiens_hsa047440.25423585
103Hippo signaling pathway_Homo sapiens_hsa043900.24404281
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.24051626
105Pancreatic cancer_Homo sapiens_hsa052120.23932640
106Arachidonic acid metabolism_Homo sapiens_hsa005900.23480793
107FoxO signaling pathway_Homo sapiens_hsa040680.23364634
108Huntingtons disease_Homo sapiens_hsa050160.23139624
109Olfactory transduction_Homo sapiens_hsa047400.22918477
110Viral myocarditis_Homo sapiens_hsa054160.22097742
111Chronic myeloid leukemia_Homo sapiens_hsa052200.22002105
112Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.21898589
113Toll-like receptor signaling pathway_Homo sapiens_hsa046200.21347341
114Renin-angiotensin system_Homo sapiens_hsa046140.19547700
115Caffeine metabolism_Homo sapiens_hsa002320.19528145
116Type I diabetes mellitus_Homo sapiens_hsa049400.19129389
117Jak-STAT signaling pathway_Homo sapiens_hsa046300.18025512
118Tight junction_Homo sapiens_hsa045300.18020256
119Tryptophan metabolism_Homo sapiens_hsa003800.17517953
120Proteoglycans in cancer_Homo sapiens_hsa052050.17241220
121Protein export_Homo sapiens_hsa030600.15688556
122Non-small cell lung cancer_Homo sapiens_hsa052230.15237623
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15175282
124HIF-1 signaling pathway_Homo sapiens_hsa040660.14778836
125Thyroid cancer_Homo sapiens_hsa052160.14615777
126TNF signaling pathway_Homo sapiens_hsa046680.14197539
127Tuberculosis_Homo sapiens_hsa051520.14143931
128Sulfur relay system_Homo sapiens_hsa041220.13782016
129Notch signaling pathway_Homo sapiens_hsa043300.13746468
130Adherens junction_Homo sapiens_hsa045200.13192476
131Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.13099447
132Regulation of actin cytoskeleton_Homo sapiens_hsa048100.13070852
133Folate biosynthesis_Homo sapiens_hsa007900.13029331
134Retinol metabolism_Homo sapiens_hsa008300.12460411
135Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.12438562
136Wnt signaling pathway_Homo sapiens_hsa043100.12008745
137Phagosome_Homo sapiens_hsa041450.11543144
138N-Glycan biosynthesis_Homo sapiens_hsa005100.11521195
139PI3K-Akt signaling pathway_Homo sapiens_hsa041510.10337374
140Peroxisome_Homo sapiens_hsa041460.10156539
141Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.08711534
142Drug metabolism - other enzymes_Homo sapiens_hsa009830.08045232
143Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.07997775
144Toxoplasmosis_Homo sapiens_hsa051450.07931443

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