

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of B cell receptor signaling pathway (GO:0050855) | 6.32986868 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.30331177 |
| 3 | detection of molecule of bacterial origin (GO:0032490) | 6.06838646 |
| 4 | B cell receptor signaling pathway (GO:0050853) | 5.71977237 |
| 5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.53579186 |
| 6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.53579186 |
| 7 | modulation by symbiont of host immune response (GO:0052553) | 5.53579186 |
| 8 | positive regulation by symbiont of host defense response (GO:0052509) | 5.53579186 |
| 9 | modulation by symbiont of host defense response (GO:0052031) | 5.53579186 |
| 10 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.53579186 |
| 11 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.12778929 |
| 12 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.06010069 |
| 13 | microglial cell activation (GO:0001774) | 4.88288787 |
| 14 | macrophage activation involved in immune response (GO:0002281) | 4.87117417 |
| 15 | regulation of gamma-delta T cell activation (GO:0046643) | 4.56068373 |
| 16 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.41787862 |
| 17 | negative regulation of cell killing (GO:0031342) | 4.41787862 |
| 18 | positive regulation of developmental pigmentation (GO:0048087) | 4.41498885 |
| 19 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.39536067 |
| 20 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 4.33139545 |
| 21 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.15038139 |
| 22 | cellular extravasation (GO:0045123) | 4.11955220 |
| 23 | macrophage activation (GO:0042116) | 4.07668894 |
| 24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.06234926 |
| 25 | detection of external biotic stimulus (GO:0098581) | 4.00750317 |
| 26 | negative thymic T cell selection (GO:0045060) | 3.92278038 |
| 27 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.87959758 |
| 28 | hepatocyte apoptotic process (GO:0097284) | 3.86555807 |
| 29 | negative T cell selection (GO:0043383) | 3.85913158 |
| 30 | positive thymic T cell selection (GO:0045059) | 3.83607864 |
| 31 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.82933099 |
| 32 | cellular response to ethanol (GO:0071361) | 3.81502808 |
| 33 | negative regulation of B cell proliferation (GO:0030889) | 3.80244781 |
| 34 | regulation of pigment cell differentiation (GO:0050932) | 3.77996788 |
| 35 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.77018312 |
| 36 | response to host immune response (GO:0052572) | 3.72859486 |
| 37 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.72859486 |
| 38 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.71713049 |
| 39 | regulation of B cell differentiation (GO:0045577) | 3.64434777 |
| 40 | positive T cell selection (GO:0043368) | 3.56968675 |
| 41 | B cell proliferation (GO:0042100) | 3.56360665 |
| 42 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.50506216 |
| 43 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.50506216 |
| 44 | T-helper 1 type immune response (GO:0042088) | 3.50380059 |
| 45 | fucose catabolic process (GO:0019317) | 3.50150560 |
| 46 | L-fucose metabolic process (GO:0042354) | 3.50150560 |
| 47 | L-fucose catabolic process (GO:0042355) | 3.50150560 |
| 48 | positive regulation of B cell differentiation (GO:0045579) | 3.48353192 |
| 49 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.45107737 |
| 50 | retinal rod cell development (GO:0046548) | 3.43574260 |
| 51 | detection of biotic stimulus (GO:0009595) | 3.43349826 |
| 52 | positive regulation of granulocyte differentiation (GO:0030854) | 3.39446210 |
| 53 | response to host (GO:0075136) | 3.38799770 |
| 54 | response to host defenses (GO:0052200) | 3.38799770 |
| 55 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.38799770 |
| 56 | cilium movement (GO:0003341) | 3.37808352 |
| 57 | germinal center formation (GO:0002467) | 3.35449689 |
| 58 | histone H3-K36 demethylation (GO:0070544) | 3.31456413 |
| 59 | negative regulation of T cell mediated immunity (GO:0002710) | 3.30428268 |
| 60 | neutrophil mediated immunity (GO:0002446) | 3.29926595 |
| 61 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.29057562 |
| 62 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.27142750 |
| 63 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.25654676 |
| 64 | histone H3-K4 trimethylation (GO:0080182) | 3.25566008 |
| 65 | myeloid cell activation involved in immune response (GO:0002275) | 3.22769163 |
| 66 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.21055419 |
| 67 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.16862186 |
| 68 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.16575563 |
| 69 | T cell migration (GO:0072678) | 3.15105507 |
| 70 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.13739897 |
| 71 | B cell homeostasis (GO:0001782) | 3.12506560 |
| 72 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.11579821 |
| 73 | regulation of B cell proliferation (GO:0030888) | 3.11370709 |
| 74 | establishment of protein localization to Golgi (GO:0072600) | 3.10054716 |
| 75 | axoneme assembly (GO:0035082) | 3.09224796 |
| 76 | response to interleukin-15 (GO:0070672) | 3.07887028 |
| 77 | interferon-gamma production (GO:0032609) | 3.07487647 |
| 78 | detection of other organism (GO:0098543) | 3.05585308 |
| 79 | myeloid leukocyte mediated immunity (GO:0002444) | 3.04267209 |
| 80 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.03982288 |
| 81 | defense response to protozoan (GO:0042832) | 3.02555616 |
| 82 | activated T cell proliferation (GO:0050798) | 2.98247421 |
| 83 | histone mRNA catabolic process (GO:0071044) | 2.95458009 |
| 84 | positive regulation of interferon-alpha production (GO:0032727) | 2.94960850 |
| 85 | negative regulation of interleukin-12 production (GO:0032695) | 2.93377590 |
| 86 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.92102618 |
| 87 | mature B cell differentiation (GO:0002335) | 2.91326910 |
| 88 | neural tube formation (GO:0001841) | 2.90474122 |
| 89 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.90240340 |
| 90 | negative regulation of adaptive immune response (GO:0002820) | 2.89331943 |
| 91 | T cell selection (GO:0045058) | 2.87448848 |
| 92 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 2.86630251 |
| 93 | protein targeting to Golgi (GO:0000042) | 2.85650833 |
| 94 | epithelial cilium movement (GO:0003351) | 2.85373726 |
| 95 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.84840684 |
| 96 | Peyers patch development (GO:0048541) | 2.84840684 |
| 97 | positive regulation of B cell proliferation (GO:0030890) | 2.83534499 |
| 98 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.80788660 |
| 99 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.80389637 |
| 100 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.80366214 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 5.56811722 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.98532929 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.73509351 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.62078261 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.29267081 |
| 6 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.10528405 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.96269421 |
| 8 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.75827148 |
| 9 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.74668715 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.62519223 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.59337679 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.58425383 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.58230457 |
| 14 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.37986649 |
| 15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.37637511 |
| 16 | MYB_26560356_Chip-Seq_TH2_Human | 2.29368164 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.27672910 |
| 18 | GATA1_22025678_ChIP-Seq_K562_Human | 2.27195051 |
| 19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.98778796 |
| 20 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.87693206 |
| 21 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.80808008 |
| 22 | MYB_26560356_Chip-Seq_TH1_Human | 1.79614834 |
| 23 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.77421826 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.74841588 |
| 25 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.74672866 |
| 26 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.71672364 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.69992326 |
| 28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.68829907 |
| 29 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.65390253 |
| 30 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.64822081 |
| 31 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.62169615 |
| 32 | SPI1_23127762_ChIP-Seq_K562_Human | 1.59579207 |
| 33 | GATA3_26560356_Chip-Seq_TH2_Human | 1.59368168 |
| 34 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.57526493 |
| 35 | TP53_16413492_ChIP-PET_HCT116_Human | 1.56802608 |
| 36 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.56613088 |
| 37 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.49409363 |
| 38 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.44439522 |
| 39 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.43842812 |
| 40 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.38076136 |
| 41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.37817107 |
| 42 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.37155999 |
| 43 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37155999 |
| 44 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.35059824 |
| 45 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27946504 |
| 46 | MYC_22102868_ChIP-Seq_BL_Human | 1.26801362 |
| 47 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.25825442 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22610189 |
| 49 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.19184349 |
| 50 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17357798 |
| 51 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.16970204 |
| 52 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.14912542 |
| 53 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13962125 |
| 54 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.13248969 |
| 55 | MAF_26560356_Chip-Seq_TH1_Human | 1.13111244 |
| 56 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.11752324 |
| 57 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.10619357 |
| 58 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10345925 |
| 59 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.10254210 |
| 60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.10024383 |
| 61 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.09888398 |
| 62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.08707891 |
| 63 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07404300 |
| 64 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.07179869 |
| 65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.06558072 |
| 66 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05952909 |
| 67 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.05044759 |
| 68 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.02342818 |
| 69 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.99103258 |
| 70 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98382408 |
| 71 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.96756501 |
| 72 | GATA2_19941826_ChIP-Seq_K562_Human | 0.95422813 |
| 73 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.94067241 |
| 74 | UTX_26944678_Chip-Seq_JUKART_Human | 0.93979369 |
| 75 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92790334 |
| 76 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.91079775 |
| 77 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.90989243 |
| 78 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.90584457 |
| 79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.90070090 |
| 80 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.89625559 |
| 81 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.89141976 |
| 82 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.89066930 |
| 83 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.88733660 |
| 84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.87386454 |
| 85 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.86188353 |
| 86 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.86113344 |
| 87 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.85810041 |
| 88 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.84893863 |
| 89 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.84786488 |
| 90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.84668558 |
| 91 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.83803112 |
| 92 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.83721738 |
| 93 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.83569854 |
| 94 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.82440306 |
| 95 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.81744329 |
| 96 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.81588495 |
| 97 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.81296815 |
| 98 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.81200327 |
| 99 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.80537061 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.80433619 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004381_abnormal_hair_follicle | 4.34270351 |
| 2 | MP0000569_abnormal_digit_pigmentation | 4.07686844 |
| 3 | MP0008057_abnormal_DNA_replication | 3.46135570 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.44116037 |
| 5 | MP0003724_increased_susceptibility_to | 3.07039272 |
| 6 | MP0001800_abnormal_humoral_immune | 2.99114094 |
| 7 | MP0008260_abnormal_autophagy | 2.98167653 |
| 8 | MP0003136_yellow_coat_color | 2.96836403 |
| 9 | MP0005075_abnormal_melanosome_morpholog | 2.93008268 |
| 10 | MP0000685_abnormal_immune_system | 2.85047155 |
| 11 | MP0003763_abnormal_thymus_physiology | 2.72117033 |
| 12 | MP0002166_altered_tumor_susceptibility | 2.65983855 |
| 13 | MP0003787_abnormal_imprinting | 2.58493591 |
| 14 | MP0002009_preneoplasia | 2.39046551 |
| 15 | MP0001790_abnormal_immune_system | 2.38124206 |
| 16 | MP0005387_immune_system_phenotype | 2.38124206 |
| 17 | MP0003303_peritoneal_inflammation | 2.36003712 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.21879994 |
| 19 | MP0002723_abnormal_immune_serum | 2.21263936 |
| 20 | MP0005310_abnormal_salivary_gland | 2.18352051 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.17557755 |
| 22 | MP0005000_abnormal_immune_tolerance | 2.16422045 |
| 23 | MP0005671_abnormal_response_to | 2.11991089 |
| 24 | MP0001819_abnormal_immune_cell | 2.11179959 |
| 25 | MP0002419_abnormal_innate_immunity | 2.00305942 |
| 26 | MP0003436_decreased_susceptibility_to | 1.92581562 |
| 27 | MP0002398_abnormal_bone_marrow | 1.92251297 |
| 28 | MP0000716_abnormal_immune_system | 1.84013920 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.81013313 |
| 30 | MP0005025_abnormal_response_to | 1.74549525 |
| 31 | MP0000689_abnormal_spleen_morphology | 1.70769837 |
| 32 | MP0003183_abnormal_peptide_metabolism | 1.68191715 |
| 33 | MP0002006_tumorigenesis | 1.66796528 |
| 34 | MP0002396_abnormal_hematopoietic_system | 1.63932767 |
| 35 | MP0002405_respiratory_system_inflammati | 1.60359362 |
| 36 | MP0002722_abnormal_immune_system | 1.57298391 |
| 37 | MP0005451_abnormal_body_composition | 1.53881165 |
| 38 | MP0000703_abnormal_thymus_morphology | 1.52950647 |
| 39 | MP0003045_fibrosis | 1.48692648 |
| 40 | MP0003221_abnormal_cardiomyocyte_apopto | 1.46326060 |
| 41 | MP0009785_altered_susceptibility_to | 1.42213275 |
| 42 | MP0000015_abnormal_ear_pigmentation | 1.41599524 |
| 43 | MP0004883_abnormal_blood_vessel | 1.41523102 |
| 44 | MP0008004_abnormal_stomach_pH | 1.41307363 |
| 45 | MP0002429_abnormal_blood_cell | 1.40270418 |
| 46 | MP0005408_hypopigmentation | 1.39318626 |
| 47 | MP0003866_abnormal_defecation | 1.32346041 |
| 48 | MP0002163_abnormal_gland_morphology | 1.27440358 |
| 49 | MP0003172_abnormal_lysosome_physiology | 1.27098188 |
| 50 | MP0003300_gastrointestinal_ulcer | 1.25375286 |
| 51 | MP0002132_abnormal_respiratory_system | 1.24894967 |
| 52 | MP0002148_abnormal_hypersensitivity_rea | 1.24741266 |
| 53 | MP0000013_abnormal_adipose_tissue | 1.23817741 |
| 54 | MP0005464_abnormal_platelet_physiology | 1.23801849 |
| 55 | MP0000371_diluted_coat_color | 1.23050281 |
| 56 | MP0003191_abnormal_cellular_cholesterol | 1.20158115 |
| 57 | MP0001845_abnormal_inflammatory_respons | 1.20053472 |
| 58 | MP0002653_abnormal_ependyma_morphology | 1.19890520 |
| 59 | MP0003656_abnormal_erythrocyte_physiolo | 1.16784837 |
| 60 | MP0003828_pulmonary_edema | 1.14631001 |
| 61 | MP0008961_abnormal_basal_metabolism | 1.11126309 |
| 62 | MP0004808_abnormal_hematopoietic_stem | 1.09155205 |
| 63 | MP0008995_early_reproductive_senescence | 1.08062766 |
| 64 | MP0004947_skin_inflammation | 1.06811859 |
| 65 | MP0000372_irregular_coat_pigmentation | 0.98223314 |
| 66 | MP0002095_abnormal_skin_pigmentation | 0.98212454 |
| 67 | MP0000427_abnormal_hair_cycle | 0.95910397 |
| 68 | MP0005379_endocrine/exocrine_gland_phen | 0.94783845 |
| 69 | MP0004484_altered_response_of | 0.94072985 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.92638249 |
| 71 | MP0005174_abnormal_tail_pigmentation | 0.92225807 |
| 72 | MP0005397_hematopoietic_system_phenotyp | 0.90088238 |
| 73 | MP0001545_abnormal_hematopoietic_system | 0.90088238 |
| 74 | MP0000003_abnormal_adipose_tissue | 0.87424693 |
| 75 | MP0009115_abnormal_fat_cell | 0.87279878 |
| 76 | MP0005164_abnormal_response_to | 0.83512473 |
| 77 | MP0002019_abnormal_tumor_incidence | 0.78441354 |
| 78 | MP0010155_abnormal_intestine_physiology | 0.77816036 |
| 79 | MP0006082_CNS_inflammation | 0.77472545 |
| 80 | MP0003091_abnormal_cell_migration | 0.75912164 |
| 81 | MP0001186_pigmentation_phenotype | 0.75858805 |
| 82 | MP0001853_heart_inflammation | 0.73732298 |
| 83 | MP0005076_abnormal_cell_differentiation | 0.71989269 |
| 84 | MP0003690_abnormal_glial_cell | 0.71033776 |
| 85 | MP0001851_eye_inflammation | 0.70933399 |
| 86 | MP0008469_abnormal_protein_level | 0.66775739 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.65127227 |
| 88 | MP0010307_abnormal_tumor_latency | 0.64978807 |
| 89 | MP0003195_calcinosis | 0.64532977 |
| 90 | MP0002933_joint_inflammation | 0.61963088 |
| 91 | MP0002136_abnormal_kidney_physiology | 0.61610140 |
| 92 | MP0010386_abnormal_urinary_bladder | 0.61168774 |
| 93 | MP0003121_genomic_imprinting | 0.61017807 |
| 94 | MP0001663_abnormal_digestive_system | 0.60679340 |
| 95 | MP0003632_abnormal_nervous_system | 0.60333164 |
| 96 | MP0002075_abnormal_coat/hair_pigmentati | 0.60168655 |
| 97 | MP0004130_abnormal_muscle_cell | 0.58728172 |
| 98 | MP0009764_decreased_sensitivity_to | 0.57413534 |
| 99 | MP0001533_abnormal_skeleton_physiology | 0.56089908 |
| 100 | MP0004142_abnormal_muscle_tone | 0.55548348 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 5.46573252 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 5.46573252 |
| 3 | Recurrent bronchitis (HP:0002837) | 4.73358776 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 4.46974382 |
| 5 | T lymphocytopenia (HP:0005403) | 4.02718459 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.00935115 |
| 7 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.93708643 |
| 8 | Recurrent sinusitis (HP:0011108) | 3.84084138 |
| 9 | Recurrent fungal infections (HP:0002841) | 3.82399200 |
| 10 | Abnormality of T cell number (HP:0011839) | 3.78388668 |
| 11 | Recurrent cutaneous fungal infections (HP:0011370) | 3.71153905 |
| 12 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.71153905 |
| 13 | Recurrent abscess formation (HP:0002722) | 3.70246263 |
| 14 | Abnormal ciliary motility (HP:0012262) | 3.68941510 |
| 15 | Bronchitis (HP:0012387) | 3.56656967 |
| 16 | Retrobulbar optic neuritis (HP:0100654) | 3.55986657 |
| 17 | Optic neuritis (HP:0100653) | 3.55986657 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.52330117 |
| 19 | Chronic hepatic failure (HP:0100626) | 3.52130459 |
| 20 | Panhypogammaglobulinemia (HP:0003139) | 3.49871844 |
| 21 | Recurrent viral infections (HP:0004429) | 3.46032928 |
| 22 | Gingivitis (HP:0000230) | 3.37297264 |
| 23 | Colitis (HP:0002583) | 3.30565851 |
| 24 | Orchitis (HP:0100796) | 3.26093548 |
| 25 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.24473770 |
| 26 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.24473770 |
| 27 | Mediastinal lymphadenopathy (HP:0100721) | 3.23246669 |
| 28 | Eczematoid dermatitis (HP:0000976) | 3.19105054 |
| 29 | Meningitis (HP:0001287) | 3.18382249 |
| 30 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.17986527 |
| 31 | Myositis (HP:0100614) | 3.17645836 |
| 32 | Recurrent skin infections (HP:0001581) | 3.15645490 |
| 33 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.11643182 |
| 34 | Hypoplasia of the thymus (HP:0000778) | 3.10699739 |
| 35 | Bronchiectasis (HP:0002110) | 3.10319240 |
| 36 | Encephalitis (HP:0002383) | 3.02941087 |
| 37 | Vasculitis (HP:0002633) | 3.01490428 |
| 38 | Chronic otitis media (HP:0000389) | 2.97584058 |
| 39 | Menstrual irregularities (HP:0000858) | 2.91560712 |
| 40 | Abnormality of the fingertips (HP:0001211) | 2.89748121 |
| 41 | Agammaglobulinemia (HP:0004432) | 2.89625306 |
| 42 | Gastrointestinal infarctions (HP:0005244) | 2.84987919 |
| 43 | IgA deficiency (HP:0002720) | 2.84283531 |
| 44 | Viral hepatitis (HP:0006562) | 2.83442713 |
| 45 | Lymphopenia (HP:0001888) | 2.82706666 |
| 46 | Autoimmune hemolytic anemia (HP:0001890) | 2.80175929 |
| 47 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.75941406 |
| 48 | Abnormality of T cells (HP:0002843) | 2.75857826 |
| 49 | Recurrent pneumonia (HP:0006532) | 2.71325109 |
| 50 | Keratoconjunctivitis sicca (HP:0001097) | 2.69263360 |
| 51 | Chronic sinusitis (HP:0011109) | 2.63319472 |
| 52 | Inflammation of the large intestine (HP:0002037) | 2.59248358 |
| 53 | Abnormal hair whorl (HP:0010721) | 2.57314424 |
| 54 | Spontaneous hematomas (HP:0007420) | 2.55217468 |
| 55 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.54959304 |
| 56 | Thoracolumbar scoliosis (HP:0002944) | 2.53350561 |
| 57 | Recurrent otitis media (HP:0000403) | 2.52629393 |
| 58 | Keratoconjunctivitis (HP:0001096) | 2.52175455 |
| 59 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.51678925 |
| 60 | Tubulointerstitial nephritis (HP:0001970) | 2.51213067 |
| 61 | IgM deficiency (HP:0002850) | 2.48598652 |
| 62 | Cellulitis (HP:0100658) | 2.41978736 |
| 63 | Truncal obesity (HP:0001956) | 2.38674822 |
| 64 | Cone-rod dystrophy (HP:0000548) | 2.38443163 |
| 65 | Stomach cancer (HP:0012126) | 2.38310546 |
| 66 | Rhinitis (HP:0012384) | 2.37951866 |
| 67 | Nasal polyposis (HP:0100582) | 2.35954007 |
| 68 | Gastrointestinal inflammation (HP:0004386) | 2.34543715 |
| 69 | Thyroiditis (HP:0100646) | 2.23344671 |
| 70 | Slow saccadic eye movements (HP:0000514) | 2.21942731 |
| 71 | Arterial thrombosis (HP:0004420) | 2.21744026 |
| 72 | Recurrent lower respiratory tract infections (HP:0002783) | 2.20008112 |
| 73 | Hemoptysis (HP:0002105) | 2.18576494 |
| 74 | Chronic diarrhea (HP:0002028) | 2.18250250 |
| 75 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16947857 |
| 76 | Fatigue (HP:0012378) | 2.16567516 |
| 77 | Gastrointestinal stroma tumor (HP:0100723) | 2.16267650 |
| 78 | Chest pain (HP:0100749) | 2.16124353 |
| 79 | Papillary thyroid carcinoma (HP:0002895) | 2.15804128 |
| 80 | Genetic anticipation (HP:0003743) | 2.10191442 |
| 81 | Stomatitis (HP:0010280) | 2.10129503 |
| 82 | Gingival bleeding (HP:0000225) | 2.08430429 |
| 83 | Prominent nose (HP:0000448) | 2.05759633 |
| 84 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.05632685 |
| 85 | Submucous cleft hard palate (HP:0000176) | 2.00296558 |
| 86 | Leukocytosis (HP:0001974) | 1.98869341 |
| 87 | Pulmonary infiltrates (HP:0002113) | 1.98049290 |
| 88 | Acute hepatic failure (HP:0006554) | 1.94296415 |
| 89 | Abnormality of the peritoneum (HP:0002585) | 1.91217426 |
| 90 | Subacute progressive viral hepatitis (HP:0006572) | 1.91104538 |
| 91 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.88911292 |
| 92 | Lymphoma (HP:0002665) | 1.87966329 |
| 93 | Rhabdomyosarcoma (HP:0002859) | 1.87901502 |
| 94 | Chronic bronchitis (HP:0004469) | 1.86908881 |
| 95 | Obstructive lung disease (HP:0006536) | 1.86593784 |
| 96 | Chronic obstructive pulmonary disease (HP:0006510) | 1.86593784 |
| 97 | Constricted visual fields (HP:0001133) | 1.86311307 |
| 98 | Abnormality of B cell number (HP:0010975) | 1.85708599 |
| 99 | Eosinophilia (HP:0001880) | 1.85607097 |
| 100 | IgG deficiency (HP:0004315) | 1.81606854 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.15487315 |
| 2 | BLK | 3.50151554 |
| 3 | IRAK4 | 3.30526316 |
| 4 | FRK | 2.75916306 |
| 5 | TYK2 | 2.34407057 |
| 6 | MAP2K3 | 2.20092277 |
| 7 | MAP4K1 | 2.18493849 |
| 8 | SGK2 | 2.14265882 |
| 9 | BTK | 2.03425526 |
| 10 | SYK | 1.97967969 |
| 11 | WNK1 | 1.95304344 |
| 12 | TAOK3 | 1.92543988 |
| 13 | MAP3K2 | 1.90933699 |
| 14 | IKBKE | 1.88274431 |
| 15 | CDK12 | 1.88231047 |
| 16 | GRK6 | 1.84731553 |
| 17 | CSK | 1.78342381 |
| 18 | TEC | 1.75191108 |
| 19 | JAK1 | 1.75069241 |
| 20 | SGK3 | 1.67481309 |
| 21 | IRAK1 | 1.61100481 |
| 22 | NLK | 1.55173169 |
| 23 | MAP3K14 | 1.51829606 |
| 24 | JAK3 | 1.48140463 |
| 25 | SGK223 | 1.43794617 |
| 26 | SGK494 | 1.43794617 |
| 27 | TXK | 1.42831031 |
| 28 | PIK3CG | 1.41976467 |
| 29 | MAP3K13 | 1.41709885 |
| 30 | FES | 1.38150681 |
| 31 | ITK | 1.38144850 |
| 32 | MST4 | 1.37017841 |
| 33 | PIM1 | 1.33890812 |
| 34 | TLK1 | 1.31083695 |
| 35 | IRAK2 | 1.29845506 |
| 36 | STK4 | 1.29662432 |
| 37 | FGR | 1.29071778 |
| 38 | JAK2 | 1.27264708 |
| 39 | LRRK2 | 1.26425694 |
| 40 | TNIK | 1.24804805 |
| 41 | BMPR2 | 1.23684361 |
| 42 | LYN | 1.21114762 |
| 43 | ACVR1B | 1.20293093 |
| 44 | FGFR3 | 1.13611530 |
| 45 | HCK | 1.12666418 |
| 46 | FGFR2 | 1.10737138 |
| 47 | ZAP70 | 1.07645215 |
| 48 | STK24 | 1.06549497 |
| 49 | MAP3K1 | 1.04139979 |
| 50 | MAP3K5 | 1.02911464 |
| 51 | PTK2B | 0.98022577 |
| 52 | MAP2K4 | 0.96068393 |
| 53 | SGK1 | 0.94773524 |
| 54 | PRKCQ | 0.93858248 |
| 55 | CAMKK2 | 0.90577077 |
| 56 | YES1 | 0.88145091 |
| 57 | IKBKB | 0.85755935 |
| 58 | MAP3K6 | 0.83779325 |
| 59 | EIF2AK3 | 0.79720501 |
| 60 | MELK | 0.78972809 |
| 61 | MAPK7 | 0.78742957 |
| 62 | STK16 | 0.76781173 |
| 63 | KSR2 | 0.76226282 |
| 64 | BRD4 | 0.75145235 |
| 65 | LCK | 0.74472556 |
| 66 | MAP3K3 | 0.74035093 |
| 67 | MARK2 | 0.73523045 |
| 68 | PDK1 | 0.72922690 |
| 69 | ERBB2 | 0.66935577 |
| 70 | DAPK2 | 0.66572048 |
| 71 | ZAK | 0.62419574 |
| 72 | STK10 | 0.59580867 |
| 73 | MAP3K7 | 0.56992473 |
| 74 | PRPF4B | 0.55341995 |
| 75 | CDK4 | 0.55132259 |
| 76 | CDK6 | 0.54323835 |
| 77 | STK11 | 0.54108153 |
| 78 | TRIB3 | 0.51560107 |
| 79 | STK38L | 0.50902038 |
| 80 | EGFR | 0.47692077 |
| 81 | TNK2 | 0.45668509 |
| 82 | CHUK | 0.45332667 |
| 83 | CSF1R | 0.45299542 |
| 84 | PAK3 | 0.45208487 |
| 85 | DYRK1A | 0.44467197 |
| 86 | MAPK11 | 0.43789421 |
| 87 | BRSK2 | 0.43502469 |
| 88 | STK38 | 0.41692699 |
| 89 | NEK6 | 0.40732829 |
| 90 | PDPK1 | 0.40317151 |
| 91 | RPS6KB1 | 0.38116711 |
| 92 | PRKAA2 | 0.37191470 |
| 93 | EPHB1 | 0.36850212 |
| 94 | KIT | 0.36779136 |
| 95 | MATK | 0.36514818 |
| 96 | CAMK4 | 0.36390740 |
| 97 | FYN | 0.36346371 |
| 98 | RPS6KB2 | 0.35495993 |
| 99 | BMPR1B | 0.35313452 |
| 100 | HIPK2 | 0.34160104 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 3.45807950 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.70566764 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.62221206 |
| 4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.26911446 |
| 5 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.07385394 |
| 6 | Tuberculosis_Homo sapiens_hsa05152 | 2.04529037 |
| 7 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.03764323 |
| 8 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.00678024 |
| 9 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.96941293 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 1.87705374 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.85810453 |
| 12 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.84586763 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.82778358 |
| 14 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.81247998 |
| 15 | Measles_Homo sapiens_hsa05162 | 1.77064539 |
| 16 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.75386768 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.73460068 |
| 18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.71268341 |
| 19 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.69944374 |
| 20 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.64693867 |
| 21 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.64281428 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.62223888 |
| 23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.52328273 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.51643510 |
| 25 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.50759317 |
| 26 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.46321354 |
| 27 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.46124011 |
| 28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.43961249 |
| 29 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.37000000 |
| 30 | Hepatitis B_Homo sapiens_hsa05161 | 1.35780839 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.34388934 |
| 32 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.32545628 |
| 33 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.29028991 |
| 34 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.24504488 |
| 35 | Asthma_Homo sapiens_hsa05310 | 1.23737371 |
| 36 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.22152158 |
| 37 | Prostate cancer_Homo sapiens_hsa05215 | 1.20956559 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.15334667 |
| 39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.12689625 |
| 40 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.11152267 |
| 41 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.10510218 |
| 42 | Endometrial cancer_Homo sapiens_hsa05213 | 1.08151838 |
| 43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.06175187 |
| 44 | Legionellosis_Homo sapiens_hsa05134 | 1.04538351 |
| 45 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.04410103 |
| 46 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03621383 |
| 47 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.01939608 |
| 48 | Apoptosis_Homo sapiens_hsa04210 | 0.99436639 |
| 49 | Malaria_Homo sapiens_hsa05144 | 0.99393130 |
| 50 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.98901803 |
| 51 | Platelet activation_Homo sapiens_hsa04611 | 0.97698576 |
| 52 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.96625195 |
| 53 | Hepatitis C_Homo sapiens_hsa05160 | 0.94819832 |
| 54 | Colorectal cancer_Homo sapiens_hsa05210 | 0.92478664 |
| 55 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.92175852 |
| 56 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.83632468 |
| 57 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.82585672 |
| 58 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.81767418 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.79625604 |
| 60 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.77867539 |
| 61 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.76043287 |
| 62 | Alcoholism_Homo sapiens_hsa05034 | 0.74460751 |
| 63 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.70820798 |
| 64 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67655867 |
| 65 | Long-term potentiation_Homo sapiens_hsa04720 | 0.67318673 |
| 66 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.67298804 |
| 67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.66785846 |
| 68 | Taste transduction_Homo sapiens_hsa04742 | 0.65525094 |
| 69 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.65342182 |
| 70 | Insulin resistance_Homo sapiens_hsa04931 | 0.65214354 |
| 71 | Phagosome_Homo sapiens_hsa04145 | 0.65177716 |
| 72 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.64085931 |
| 73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64054214 |
| 74 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.63434504 |
| 75 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.63250632 |
| 76 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.63135794 |
| 77 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.62875406 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.61661273 |
| 79 | Glioma_Homo sapiens_hsa05214 | 0.61506261 |
| 80 | ABC transporters_Homo sapiens_hsa02010 | 0.61416309 |
| 81 | Thyroid cancer_Homo sapiens_hsa05216 | 0.59068279 |
| 82 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.53354551 |
| 83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.52325789 |
| 84 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.51148059 |
| 85 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50949436 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.50424185 |
| 87 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48481667 |
| 88 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.47644017 |
| 89 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.46246398 |
| 90 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.45722107 |
| 91 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.45280006 |
| 92 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44464519 |
| 93 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.43774856 |
| 94 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.43600089 |
| 95 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.43121626 |
| 96 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.41060259 |
| 97 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.39955134 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39928492 |
| 99 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.39827978 |
| 100 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.38173956 |

