CEP162

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA double-strand break processing (GO:0000729)4.48382324
2regulation of cilium movement (GO:0003352)4.24783346
3microtubule polymerization or depolymerization (GO:0031109)4.03142656
4protein localization to cilium (GO:0061512)3.80775251
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.70733339
6behavioral response to nicotine (GO:0035095)3.69290424
7histone H3-K4 trimethylation (GO:0080182)3.68401649
8limb bud formation (GO:0060174)3.67293988
9protein polyglutamylation (GO:0018095)3.63825249
10regulation of meiosis I (GO:0060631)3.63323521
11negative regulation of DNA-dependent DNA replication (GO:2000104)3.63135279
12regulation of DNA endoreduplication (GO:0032875)3.62136978
13CENP-A containing nucleosome assembly (GO:0034080)3.56555005
14intra-S DNA damage checkpoint (GO:0031573)3.53674305
15behavioral response to ethanol (GO:0048149)3.53407598
16axoneme assembly (GO:0035082)3.51467987
17somite development (GO:0061053)3.44568977
18cilium or flagellum-dependent cell motility (GO:0001539)3.42294812
19histone exchange (GO:0043486)3.41715421
20sperm motility (GO:0030317)3.40993631
21establishment of protein localization to Golgi (GO:0072600)3.39444045
22cilium morphogenesis (GO:0060271)3.34215629
23double-strand break repair via homologous recombination (GO:0000724)3.33676487
24recombinational repair (GO:0000725)3.33601513
25somite rostral/caudal axis specification (GO:0032525)3.28241417
26meiotic chromosome segregation (GO:0045132)3.28231124
27olfactory bulb development (GO:0021772)3.25442093
28resolution of meiotic recombination intermediates (GO:0000712)3.24775445
29regulation of centriole replication (GO:0046599)3.21907774
30kinetochore organization (GO:0051383)3.20812940
31DNA strand renaturation (GO:0000733)3.20070408
32left/right axis specification (GO:0070986)3.19789335
33ventricular system development (GO:0021591)3.17599402
34protein targeting to Golgi (GO:0000042)3.13467826
35centriole assembly (GO:0098534)3.13154543
36protein prenylation (GO:0018342)3.08296470
37prenylation (GO:0097354)3.08296470
38centriole replication (GO:0007099)3.06555180
39retinal cone cell development (GO:0046549)3.06167417
40negative regulation of transcription regulatory region DNA binding (GO:2000678)3.05465071
41single strand break repair (GO:0000012)3.02156924
42regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.98151553
43regulation of mitotic spindle checkpoint (GO:1903504)2.98151553
44kinetochore assembly (GO:0051382)2.96230631
45photoreceptor cell maintenance (GO:0045494)2.94051745
46replicative senescence (GO:0090399)2.92616979
47retrograde transport, vesicle recycling within Golgi (GO:0000301)2.91909731
48intraciliary transport (GO:0042073)2.91862966
49interkinetic nuclear migration (GO:0022027)2.90888031
50peptidyl-lysine trimethylation (GO:0018023)2.89111714
51smoothened signaling pathway (GO:0007224)2.88994877
52appendage development (GO:0048736)2.86873563
53limb development (GO:0060173)2.86873563
54seminiferous tubule development (GO:0072520)2.86361047
55presynaptic membrane organization (GO:0097090)2.86292520
56microtubule organizing center organization (GO:0031023)2.85452717
57centrosome organization (GO:0051297)2.85153927
58DNA replication-independent nucleosome organization (GO:0034724)2.84826297
59DNA replication-independent nucleosome assembly (GO:0006336)2.84826297
60response to pheromone (GO:0019236)2.80870052
61protein neddylation (GO:0045116)2.80426705
62* cellular component assembly involved in morphogenesis (GO:0010927)2.80107439
63histone H3-K4 methylation (GO:0051568)2.77097654
64mitotic sister chromatid cohesion (GO:0007064)2.76795784
65DNA synthesis involved in DNA repair (GO:0000731)2.76552407
66definitive hemopoiesis (GO:0060216)2.73893698
67sister chromatid cohesion (GO:0007062)2.72444603
68poly(A)+ mRNA export from nucleus (GO:0016973)2.70756699
69retinal rod cell development (GO:0046548)2.69490103
70detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.67597740
71pyrimidine nucleobase catabolic process (GO:0006208)2.65907447
72DNA methylation involved in gamete generation (GO:0043046)2.65286909
73reciprocal DNA recombination (GO:0035825)2.65242191
74reciprocal meiotic recombination (GO:0007131)2.65242191
75mesenchymal cell differentiation involved in kidney development (GO:0072161)2.64424198
76mesenchymal cell differentiation involved in renal system development (GO:2001012)2.64424198
77acrosome reaction (GO:0007340)2.64030241
78regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.63134278
79protein localization to Golgi apparatus (GO:0034067)2.62468418
80epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.61897620
81regulation of nuclear cell cycle DNA replication (GO:0033262)2.61723428
82regulation of mesoderm development (GO:2000380)2.60743500
83male meiosis (GO:0007140)2.57670352
84DNA replication checkpoint (GO:0000076)2.57612578
85negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.57564956
86cilium movement (GO:0003341)2.56586018
87DNA-dependent DNA replication (GO:0006261)2.56502647
88kidney morphogenesis (GO:0060993)2.53649903
89positive regulation of gamma-delta T cell activation (GO:0046645)2.52351617
90melanocyte differentiation (GO:0030318)2.51755065
91cell proliferation in forebrain (GO:0021846)2.51511732
92piRNA metabolic process (GO:0034587)2.50388691
93positive regulation of antigen processing and presentation (GO:0002579)2.48884422
94somatic hypermutation of immunoglobulin genes (GO:0016446)2.48297056
95somatic diversification of immune receptors via somatic mutation (GO:0002566)2.48297056
96G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.47433876
97synapsis (GO:0007129)2.47403551
98epithelial cilium movement (GO:0003351)2.47063895
99G-protein coupled receptor internalization (GO:0002031)2.45887626
100spermatid nucleus differentiation (GO:0007289)2.45391586
101histone H2A acetylation (GO:0043968)2.45287897
102dendritic cell chemotaxis (GO:0002407)2.44843611
103neural tube formation (GO:0001841)2.43315390
104protein K11-linked deubiquitination (GO:0035871)2.42640208
105microtubule anchoring (GO:0034453)2.42564255
106cerebral cortex radially oriented cell migration (GO:0021799)2.42550557
107microtubule bundle formation (GO:0001578)2.42421112
108transmission of nerve impulse (GO:0019226)2.42393093
109regulation of centrosome duplication (GO:0010824)2.42312362
110metaphase plate congression (GO:0051310)2.41276507
111maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.41022847
112determination of left/right symmetry (GO:0007368)2.40900999
113photoreceptor cell development (GO:0042461)2.40529950
114histone H3-K9 methylation (GO:0051567)2.40335704
115replication fork processing (GO:0031297)2.39643468
116axonemal dynein complex assembly (GO:0070286)2.37848297
117regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.37113592
118superoxide anion generation (GO:0042554)2.35368903
119nuclear pore complex assembly (GO:0051292)2.35263320
120regulation of dendritic cell antigen processing and presentation (GO:0002604)2.33710640
121dendritic cell migration (GO:0036336)2.33601676
122regulation of RIG-I signaling pathway (GO:0039535)2.32834744
123negative regulation of translation, ncRNA-mediated (GO:0040033)2.31273168
124regulation of translation, ncRNA-mediated (GO:0045974)2.31273168
125negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.31273168
126DNA ligation (GO:0006266)2.28179943
127pigment cell differentiation (GO:0050931)2.28097189
128female gonad development (GO:0008585)2.27871502
129neuroepithelial cell differentiation (GO:0060563)2.27634671
130chromosome organization involved in meiosis (GO:0070192)2.26598911
131acrosome assembly (GO:0001675)2.26400500
132histone H3-K36 demethylation (GO:0070544)2.25979085
133negative regulation of keratinocyte proliferation (GO:0010839)2.25680431
134positive regulation of interleukin-1 beta secretion (GO:0050718)2.25174645
135response to X-ray (GO:0010165)2.24922192
136protein K6-linked ubiquitination (GO:0085020)2.24801156
137* cilium assembly (GO:0042384)2.24702126
138microtubule depolymerization (GO:0007019)2.23550823
139positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.23060327
140* cilium organization (GO:0044782)2.22627848
141positive regulation of cellular amide metabolic process (GO:0034250)2.22561908
142presynaptic membrane assembly (GO:0097105)2.22310404
143response to interferon-alpha (GO:0035455)2.22170840
144nucleoside diphosphate catabolic process (GO:0009134)2.21669757
145chromatin remodeling at centromere (GO:0031055)2.20300988
146histone mRNA catabolic process (GO:0071044)2.20216949
147regulation of non-canonical Wnt signaling pathway (GO:2000050)2.19800997
148regulation of antigen processing and presentation (GO:0002577)2.18971374
149response to peptidoglycan (GO:0032494)2.18757243
150modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.18695310
151positive regulation by organism of defense response of other organism involved in symbiotic interact2.18695310
152modulation by symbiont of host immune response (GO:0052553)2.18695310
153positive regulation by symbiont of host defense response (GO:0052509)2.18695310
154modulation by symbiont of host defense response (GO:0052031)2.18695310
155modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.18695310
156nonmotile primary cilium assembly (GO:0035058)2.17628699
157pore complex assembly (GO:0046931)2.15767576
158DNA integration (GO:0015074)2.15459165
159response to muramyl dipeptide (GO:0032495)2.15124469
160regulation of B cell receptor signaling pathway (GO:0050855)2.14986992
161positive regulation of macrophage differentiation (GO:0045651)2.14817564
162lymphoid progenitor cell differentiation (GO:0002320)2.14626964
163positive regulation of defense response to virus by host (GO:0002230)2.14029167
164DNA dealkylation (GO:0035510)2.12794356
165regulation of MHC class II biosynthetic process (GO:0045346)2.12027348
166androgen biosynthetic process (GO:0006702)2.11434652
167NIK/NF-kappaB signaling (GO:0038061)2.11263657
168male meiosis I (GO:0007141)2.10437287
169detection of other organism (GO:0098543)2.08480042

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human3.92033620
2PCGF2_27294783_Chip-Seq_ESCs_Mouse2.93234771
3FLI1_27457419_Chip-Seq_LIVER_Mouse2.86269358
4ZNF274_21170338_ChIP-Seq_K562_Hela2.73865722
5GBX2_23144817_ChIP-Seq_PC3_Human2.72351943
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.70118566
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.52356848
8VDR_22108803_ChIP-Seq_LS180_Human2.49654106
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.47091051
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.46960628
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.37808302
12PCGF2_27294783_Chip-Seq_NPCs_Mouse2.32282043
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.31811674
14SUZ12_27294783_Chip-Seq_NPCs_Mouse2.30301367
15NFE2_27457419_Chip-Seq_LIVER_Mouse2.25681652
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.22490501
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.20463320
18IGF1R_20145208_ChIP-Seq_DFB_Human2.17075007
19SMAD_19615063_ChIP-ChIP_OVARY_Human2.15142405
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.14285186
21CTBP1_25329375_ChIP-Seq_LNCAP_Human2.09473223
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.08363411
23EZH2_27294783_Chip-Seq_NPCs_Mouse1.94437530
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.92308705
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.91047009
26NANOG_18555785_Chip-Seq_ESCs_Mouse1.84796021
27BP1_19119308_ChIP-ChIP_Hs578T_Human1.83940068
28E2F4_17652178_ChIP-ChIP_JURKAT_Human1.82963482
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.82694306
30EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.82672426
31UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.79735424
32SUZ12_18555785_Chip-Seq_ESCs_Mouse1.75403670
33FUS_26573619_Chip-Seq_HEK293_Human1.73984275
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73740352
35P53_22387025_ChIP-Seq_ESCs_Mouse1.73606732
36E2F1_18555785_Chip-Seq_ESCs_Mouse1.72606868
37STAT3_18555785_Chip-Seq_ESCs_Mouse1.70450726
38EWS_26573619_Chip-Seq_HEK293_Human1.69645546
39IRF8_21731497_ChIP-ChIP_J774_Mouse1.68780456
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.67631611
41CBP_20019798_ChIP-Seq_JUKART_Human1.67551287
42IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.67551287
43IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.67300722
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.65580441
45NMYC_18555785_Chip-Seq_ESCs_Mouse1.65139529
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.64443611
47STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.63092474
48AR_25329375_ChIP-Seq_VCAP_Human1.62935784
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.62770294
50BCAT_22108803_ChIP-Seq_LS180_Human1.62719277
51MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60107402
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.58969628
53OCT4_18555785_Chip-Seq_ESCs_Mouse1.57841341
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57177097
55EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.56779187
56TAF15_26573619_Chip-Seq_HEK293_Human1.56236851
57ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.54703032
58P300_18555785_Chip-Seq_ESCs_Mouse1.53404025
59CMYC_18555785_Chip-Seq_ESCs_Mouse1.49781336
60ELF1_17652178_ChIP-ChIP_JURKAT_Human1.48980802
61EZH2_22144423_ChIP-Seq_EOC_Human1.48293146
62STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.48054062
63RUNX1_27457419_Chip-Seq_LIVER_Mouse1.46328114
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.45282619
65NR3C1_21868756_ChIP-Seq_MCF10A_Human1.45214319
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44611861
67SOX2_18555785_Chip-Seq_ESCs_Mouse1.44561745
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.44174414
69ZFX_18555785_Chip-Seq_ESCs_Mouse1.43604842
70VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.42029796
71P300_19829295_ChIP-Seq_ESCs_Human1.40062002
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.39759540
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39682314
74PU1_27457419_Chip-Seq_LIVER_Mouse1.38347766
75ER_23166858_ChIP-Seq_MCF-7_Human1.37302821
76TCF4_22108803_ChIP-Seq_LS180_Human1.35534564
77PIAS1_25552417_ChIP-Seq_VCAP_Human1.35403233
78EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33950975
79CRX_20693478_ChIP-Seq_RETINA_Mouse1.33514953
80KLF4_18555785_Chip-Seq_ESCs_Mouse1.33008225
81RUNX2_22187159_ChIP-Seq_PCA_Human1.30996157
82CTCF_18555785_Chip-Seq_ESCs_Mouse1.30981892
83IRF8_27001747_Chip-Seq_BMDM_Mouse1.30793585
84HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29712950
85ESRRB_18555785_Chip-Seq_ESCs_Mouse1.28256519
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27988935
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27521891
88OCT4_21477851_ChIP-Seq_ESCs_Mouse1.27115030
89SMAD1_18555785_Chip-Seq_ESCs_Mouse1.26747788
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26264325
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26264325
92TCF4_23295773_ChIP-Seq_U87_Human1.25118020
93KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.25046096
94SMAD4_21799915_ChIP-Seq_A2780_Human1.23415516
95SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22414332
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.20914214
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.20279045
98SOX2_19829295_ChIP-Seq_ESCs_Human1.19312676
99NANOG_19829295_ChIP-Seq_ESCs_Human1.19312676
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18431610
101BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17667886
102SMAD4_21741376_ChIP-Seq_EPCs_Human1.14874470
103STAT3_23295773_ChIP-Seq_U87_Human1.14271968
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.13106272
105CBX2_27304074_Chip-Seq_ESCs_Mouse1.12626499
106FOXM1_26456572_ChIP-Seq_MCF-7_Human1.12154899
107SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.11299620
108MYC_18940864_ChIP-ChIP_HL60_Human1.10866136
109KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.10837598
110AR_21572438_ChIP-Seq_LNCaP_Human1.10803633
111PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09827974
112MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.09625102
113TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09077610
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.08522970
115ELK1_19687146_ChIP-ChIP_HELA_Human1.08489033
116RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06900250
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06889696
118TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.06829902
119CTBP2_25329375_ChIP-Seq_LNCAP_Human1.05590133
120CDX2_22108803_ChIP-Seq_LS180_Human1.04248315
121RBPJ_22232070_ChIP-Seq_NCS_Mouse1.04154376
122GABP_17652178_ChIP-ChIP_JURKAT_Human1.04135861
123EST1_17652178_ChIP-ChIP_JURKAT_Human1.02889678
124TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02695899
125CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00951106
126CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00846407
127RNF2_27304074_Chip-Seq_NSC_Mouse1.00253574
128FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.99721316
129SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.98722596
130IRF1_19129219_ChIP-ChIP_H3396_Human0.98517500
131E2F1_21310950_ChIP-Seq_MCF-7_Human0.98211913
132RUNX_20019798_ChIP-Seq_JUKART_Human0.97523569
133HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.97509300
134KDM2B_26808549_Chip-Seq_REH_Human0.96900497
135FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.96283026
136LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94415187
137STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93928063
138POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93385553
139SCL_19346495_ChIP-Seq_HPC-7_Human0.90895742
140Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.90688260

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.17290437
2MP0003787_abnormal_imprinting3.13599094
3MP0008877_abnormal_DNA_methylation2.85614550
4MP0005409_darkened_coat_color2.85430117
5MP0001188_hyperpigmentation2.83850432
6MP0003136_yellow_coat_color2.76391329
7MP0005174_abnormal_tail_pigmentation2.75315531
8MP0000015_abnormal_ear_pigmentation2.74633298
9MP0008058_abnormal_DNA_repair2.67009743
10MP0006292_abnormal_olfactory_placode2.58833346
11MP0008057_abnormal_DNA_replication2.55807105
12MP0008789_abnormal_olfactory_epithelium2.34351652
13MP0001835_abnormal_antigen_presentation2.29109619
14MP0002095_abnormal_skin_pigmentation2.25607658
15MP0001986_abnormal_taste_sensitivity2.23871919
16MP0000566_synostosis2.20789966
17MP0002653_abnormal_ependyma_morphology2.20655913
18MP0001293_anophthalmia2.20307679
19MP0006072_abnormal_retinal_apoptosis2.20279373
20MP0003880_abnormal_central_pattern2.08298370
21MP0005499_abnormal_olfactory_system2.05082949
22MP0005394_taste/olfaction_phenotype2.05082949
23MP0001529_abnormal_vocalization2.03422208
24MP0010094_abnormal_chromosome_stability2.02640818
25MP0005253_abnormal_eye_physiology1.99055881
26MP0002396_abnormal_hematopoietic_system1.98058071
27MP0005551_abnormal_eye_electrophysiolog1.97965077
28MP0002234_abnormal_pharynx_morphology1.97872260
29MP0000372_irregular_coat_pigmentation1.90987571
30MP0005671_abnormal_response_to1.84570955
31MP0001984_abnormal_olfaction1.77021356
32MP0000778_abnormal_nervous_system1.76928829
33MP0008007_abnormal_cellular_replicative1.73680634
34MP0003718_maternal_effect1.63927666
35MP0003937_abnormal_limbs/digits/tail_de1.62660885
36MP0002233_abnormal_nose_morphology1.61382813
37MP0004133_heterotaxia1.57982035
38MP0001485_abnormal_pinna_reflex1.57705286
39MP0002736_abnormal_nociception_after1.57566288
40MP0002938_white_spotting1.56757908
41MP0003763_abnormal_thymus_physiology1.55259157
42MP0002138_abnormal_hepatobiliary_system1.54247312
43MP0006276_abnormal_autonomic_nervous1.54117088
44MP0002282_abnormal_trachea_morphology1.52320057
45MP0001790_abnormal_immune_system1.47657373
46MP0005387_immune_system_phenotype1.47657373
47MP0002751_abnormal_autonomic_nervous1.44947913
48MP0002075_abnormal_coat/hair_pigmentati1.44061666
49MP0002277_abnormal_respiratory_mucosa1.42783681
50MP0005171_absent_coat_pigmentation1.39395485
51MP0005410_abnormal_fertilization1.38827517
52MP0000490_abnormal_crypts_of1.37242506
53MP0004043_abnormal_pH_regulation1.36781613
54MP0001486_abnormal_startle_reflex1.36778866
55MP0002876_abnormal_thyroid_physiology1.36730919
56MP0001186_pigmentation_phenotype1.36389128
57MP0005377_hearing/vestibular/ear_phenot1.34503861
58MP0003878_abnormal_ear_physiology1.34503861
59MP0000371_diluted_coat_color1.33354681
60MP0003121_genomic_imprinting1.32522999
61MP0002877_abnormal_melanocyte_morpholog1.31458744
62MP0003111_abnormal_nucleus_morphology1.30466007
63MP0001800_abnormal_humoral_immune1.30110763
64MP0005379_endocrine/exocrine_gland_phen1.30029521
65MP0005391_vision/eye_phenotype1.29543107
66MP0005645_abnormal_hypothalamus_physiol1.29343110
67MP0005646_abnormal_pituitary_gland1.28690020
68MP0002928_abnormal_bile_duct1.27591312
69MP0002163_abnormal_gland_morphology1.27123442
70MP0002009_preneoplasia1.26888928
71MP0000049_abnormal_middle_ear1.26179722
72MP0001286_abnormal_eye_development1.25657848
73MP0003119_abnormal_digestive_system1.24875061
74MP0003011_delayed_dark_adaptation1.24435573
75MP0005075_abnormal_melanosome_morpholog1.23411493
76MP0002210_abnormal_sex_determination1.22252280
77MP0004808_abnormal_hematopoietic_stem1.21191075
78MP0001968_abnormal_touch/_nociception1.20606178
79MP0002723_abnormal_immune_serum1.16755578
80MP0002452_abnormal_antigen_presenting1.16451016
81MP0003122_maternal_imprinting1.15829297
82MP0003786_premature_aging1.15686512
83MP0000685_abnormal_immune_system1.15680673
84MP0005195_abnormal_posterior_eye1.15239706
85MP0002148_abnormal_hypersensitivity_rea1.13353911
86MP0003693_abnormal_embryo_hatching1.12934554
87MP0003868_abnormal_feces_composition1.12479967
88MP0002420_abnormal_adaptive_immunity1.10922318
89MP0005248_abnormal_Harderian_gland1.10321269
90MP0001819_abnormal_immune_cell1.10138704
91MP0010386_abnormal_urinary_bladder1.10046054
92MP0002822_catalepsy1.09073140
93MP0002177_abnormal_outer_ear1.08980090
94MP0002638_abnormal_pupillary_reflex1.08716372
95MP0009785_altered_susceptibility_to1.07899950
96MP0000647_abnormal_sebaceous_gland1.07876497
97MP0009053_abnormal_anal_canal1.07819993
98MP0002160_abnormal_reproductive_system1.06896020
99MP0002398_abnormal_bone_marrow1.06700515
100MP0009046_muscle_twitch1.06441050
101MP0003866_abnormal_defecation1.05686141
102MP0004142_abnormal_muscle_tone1.05355477
103MP0003755_abnormal_palate_morphology1.04835874
104MP0009745_abnormal_behavioral_response1.04193926
105MP0003077_abnormal_cell_cycle1.04068681
106MP0005000_abnormal_immune_tolerance1.04045363
107MP0008995_early_reproductive_senescence1.04040904
108MP0001873_stomach_inflammation1.03321550
109MP0002752_abnormal_somatic_nervous1.03128714
110MP0001346_abnormal_lacrimal_gland1.01039817
111MP0002557_abnormal_social/conspecific_i1.00824835
112MP0001929_abnormal_gametogenesis1.00596503
113MP0003938_abnormal_ear_development0.99866580
114MP0000026_abnormal_inner_ear0.99728230
115MP0002272_abnormal_nervous_system0.99509539
116MP0000516_abnormal_urinary_system0.99091686
117MP0005367_renal/urinary_system_phenotyp0.99091686
118MP0004885_abnormal_endolymph0.98732529
119MP0002419_abnormal_innate_immunity0.98587054
120MP0003724_increased_susceptibility_to0.98235853
121MP0005310_abnormal_salivary_gland0.98051539
122MP0003045_fibrosis0.95264045
123MP0004381_abnormal_hair_follicle0.95005222
124MP0002693_abnormal_pancreas_physiology0.94712718
125MP0009697_abnormal_copulation0.94367527
126MP0003861_abnormal_nervous_system0.93261800
127MP0000716_abnormal_immune_system0.92799600
128MP0004147_increased_porphyrin_level0.92606259
129MP0002166_altered_tumor_susceptibility0.92537472
130MP0003195_calcinosis0.91805428
131MP0000428_abnormal_craniofacial_morphol0.91612552
132MP0005389_reproductive_system_phenotype0.91032652
133MP0010030_abnormal_orbit_morphology0.90492084
134MP0003183_abnormal_peptide_metabolism0.89909429
135MP0000703_abnormal_thymus_morphology0.89254779
136MP0002006_tumorigenesis0.88848509
137MP0002184_abnormal_innervation0.88678850
138MP0008932_abnormal_embryonic_tissue0.88214967
139MP0000427_abnormal_hair_cycle0.88039164
140MP0005025_abnormal_response_to0.86805257
141MP0001119_abnormal_female_reproductive0.86730111
142MP0005257_abnormal_intraocular_pressure0.86453158
143MP0005187_abnormal_penis_morphology0.86239294
144MP0002067_abnormal_sensory_capabilities0.84781089
145MP0001963_abnormal_hearing_physiology0.84749300
146MP0003698_abnormal_male_reproductive0.83723214
147MP0001270_distended_abdomen0.83604808
148MP0002109_abnormal_limb_morphology0.82225786
149MP0001145_abnormal_male_reproductive0.82180831
150MP0002254_reproductive_system_inflammat0.81711257
151MP0000955_abnormal_spinal_cord0.80975546
152MP0010155_abnormal_intestine_physiology0.80815056
153MP0002090_abnormal_vision0.80813230
154MP0000613_abnormal_salivary_gland0.80255392
155MP0003890_abnormal_embryonic-extraembry0.80210050
156MP0002697_abnormal_eye_size0.80186412
157MP0003935_abnormal_craniofacial_develop0.79433542
158MP0005395_other_phenotype0.78774562
159MP0008872_abnormal_physiological_respon0.78590217
160MP0002735_abnormal_chemical_nociception0.78122845
161MP0000653_abnormal_sex_gland0.76733742
162MP0001919_abnormal_reproductive_system0.75461546
163MP0002102_abnormal_ear_morphology0.72021406
164MP0003300_gastrointestinal_ulcer0.71956592
165MP0002722_abnormal_immune_system0.71217716
166MP0002405_respiratory_system_inflammati0.70943765
167MP0000689_abnormal_spleen_morphology0.70729316
168MP0000383_abnormal_hair_follicle0.69882219
169MP0001324_abnormal_eye_pigmentation0.69772015
170MP0000631_abnormal_neuroendocrine_gland0.69644115

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.28037505
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.11812177
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.08629313
4Intestinal atresia (HP:0011100)2.96076259
5Abnormal delayed hypersensitivity skin test (HP:0002963)2.84655141
6True hermaphroditism (HP:0010459)2.83920571
7Abnormality of the labia minora (HP:0012880)2.82035565
8Type I transferrin isoform profile (HP:0003642)2.80191790
9Median cleft lip (HP:0000161)2.77885635
10Chronic hepatic failure (HP:0100626)2.77604327
11Pancreatic fibrosis (HP:0100732)2.76929896
12Abnormality of the fingertips (HP:0001211)2.75932194
13Congenital primary aphakia (HP:0007707)2.72183712
14Abnormal hair whorl (HP:0010721)2.68794447
15Gait imbalance (HP:0002141)2.67440286
16Generalized hypopigmentation of hair (HP:0011358)2.66822735
17Oligodactyly (hands) (HP:0001180)2.65752273
18Genital tract atresia (HP:0001827)2.65519032
19Nephronophthisis (HP:0000090)2.64739671
20Abnormality of chromosome stability (HP:0003220)2.57252384
21Pancreatic cysts (HP:0001737)2.56913357
22Clubbing of toes (HP:0100760)2.56454259
23Aplasia/Hypoplasia of the fovea (HP:0008060)2.51393004
24Hypoplasia of the fovea (HP:0007750)2.51393004
25Recurrent cutaneous fungal infections (HP:0011370)2.51099251
26Chronic mucocutaneous candidiasis (HP:0002728)2.51099251
27Ectopic kidney (HP:0000086)2.48817514
28Volvulus (HP:0002580)2.48497952
29Abnormal respiratory motile cilium physiology (HP:0012261)2.48168605
30Abnormal ciliary motility (HP:0012262)2.48140439
31Hyperventilation (HP:0002883)2.47835177
32Vaginal atresia (HP:0000148)2.47297265
33Absent/shortened dynein arms (HP:0200106)2.46212592
34Dynein arm defect of respiratory motile cilia (HP:0012255)2.46212592
35Aplasia/Hypoplasia of the uvula (HP:0010293)2.45288917
36Postaxial hand polydactyly (HP:0001162)2.43192495
37Abnormality of the renal medulla (HP:0100957)2.41857644
38Nephrogenic diabetes insipidus (HP:0009806)2.37941548
39Lip pit (HP:0100267)2.35096538
40Tubulointerstitial nephritis (HP:0001970)2.33939654
41Thyroid-stimulating hormone excess (HP:0002925)2.33275469
42Abnormality of the columella (HP:0009929)2.31608316
43Supernumerary spleens (HP:0009799)2.31064024
44Sclerocornea (HP:0000647)2.30996522
45Abnormality of the nasal septum (HP:0000419)2.30956580
46Retrobulbar optic neuritis (HP:0100654)2.29636407
47Optic neuritis (HP:0100653)2.29636407
48Chronic bronchitis (HP:0004469)2.27789322
49Reduced antithrombin III activity (HP:0001976)2.23798242
50Hypothermia (HP:0002045)2.23183054
51Abnormality of the preputium (HP:0100587)2.22229892
52Meckel diverticulum (HP:0002245)2.21397133
53Bile duct proliferation (HP:0001408)2.20456942
54Abnormal biliary tract physiology (HP:0012439)2.20456942
55Gastrointestinal atresia (HP:0002589)2.20403390
56Cystic liver disease (HP:0006706)2.18675773
57Abnormality of midbrain morphology (HP:0002418)2.17313298
58Molar tooth sign on MRI (HP:0002419)2.17313298
59Poor coordination (HP:0002370)2.17267253
60Abnormal respiratory epithelium morphology (HP:0012253)2.15463416
61Abnormal respiratory motile cilium morphology (HP:0005938)2.15463416
62Colon cancer (HP:0003003)2.12731094
63Abnormality of the duodenum (HP:0002246)2.12182080
64Abnormality of incisor morphology (HP:0011063)2.11767681
65Prostate neoplasm (HP:0100787)2.10600996
66Attenuation of retinal blood vessels (HP:0007843)2.10489158
67Astigmatism (HP:0000483)2.10430787
68Abnormality of DNA repair (HP:0003254)2.10357969
69Anophthalmia (HP:0000528)2.09679669
70Bifid tongue (HP:0010297)2.09583521
71Abnormality of the renal collecting system (HP:0004742)2.08182837
72Septo-optic dysplasia (HP:0100842)2.07642130
73Triphalangeal thumb (HP:0001199)2.05059660
74Congenital hepatic fibrosis (HP:0002612)2.04159759
75Optic nerve hypoplasia (HP:0000609)2.03785837
76Narrow forehead (HP:0000341)2.02461266
77Abnormality of the ileum (HP:0001549)2.02450684
78Aganglionic megacolon (HP:0002251)2.02104711
79Agammaglobulinemia (HP:0004432)2.01014314
80Tubulointerstitial abnormality (HP:0001969)2.00845712
81Oculomotor apraxia (HP:0000657)2.00445363
82Oligodactyly (HP:0012165)1.99801162
83Acute myeloid leukemia (HP:0004808)1.99770861
84Aplasia/Hypoplasia of the tongue (HP:0010295)1.99154721
85Panhypogammaglobulinemia (HP:0003139)1.97864485
86Medial flaring of the eyebrow (HP:0010747)1.94081752
87Aplasia/Hypoplasia of the tibia (HP:0005772)1.93674274
88Recurrent fungal infections (HP:0002841)1.91773118
89Tubular atrophy (HP:0000092)1.91287956
90Congenital sensorineural hearing impairment (HP:0008527)1.90931575
91Growth hormone deficiency (HP:0000824)1.90214893
92Preaxial hand polydactyly (HP:0001177)1.90123925
93Renal cortical cysts (HP:0000803)1.90039372
94Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.89815890
95Rhinitis (HP:0012384)1.89061092
96Abolished electroretinogram (ERG) (HP:0000550)1.88845625
97Abnormal protein glycosylation (HP:0012346)1.87597556
98Abnormal glycosylation (HP:0012345)1.87597556
99Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.87597556
100Abnormal protein N-linked glycosylation (HP:0012347)1.87597556
101Postaxial foot polydactyly (HP:0001830)1.85659430
102Severe visual impairment (HP:0001141)1.85276510
103Abnormality of the fovea (HP:0000493)1.84581084
104Abnormality of the renal cortex (HP:0011035)1.83319939
105Occipital encephalocele (HP:0002085)1.83014050
106Enlarged kidneys (HP:0000105)1.82820776
107Absent frontal sinuses (HP:0002688)1.82732267
108Duplicated collecting system (HP:0000081)1.82661395
109Abnormality of the carotid arteries (HP:0005344)1.82357216
110Aplasia/Hypoplasia of the macula (HP:0008059)1.82219450
111Dandy-Walker malformation (HP:0001305)1.82173058
112Recurrent pneumonia (HP:0006532)1.81353269
113Bony spicule pigmentary retinopathy (HP:0007737)1.80618852
114Neoplasm of the tracheobronchial system (HP:0100552)1.80540227
115Abnormality of macular pigmentation (HP:0008002)1.80515860
116Hypoplastic iliac wings (HP:0002866)1.79962984
117Prominent nasal bridge (HP:0000426)1.78749793
118Oligohydramnios (HP:0001562)1.78677109
119Renal dysplasia (HP:0000110)1.78280958
120Small hand (HP:0200055)1.78051636
121Nephroblastoma (Wilms tumor) (HP:0002667)1.77806831
122Facial cleft (HP:0002006)1.76744018
123Meningitis (HP:0001287)1.76628705
124White forelock (HP:0002211)1.76046186
125Optic nerve coloboma (HP:0000588)1.76024211
126Recurrent abscess formation (HP:0002722)1.75653882
127Broad foot (HP:0001769)1.74784956
128Highly arched eyebrow (HP:0002553)1.74031066
129Ocular albinism (HP:0001107)1.73988851
130Myelodysplasia (HP:0002863)1.73444310
131Alveolar cell carcinoma (HP:0006519)1.73413392
132Febrile seizures (HP:0002373)1.73287784
133Recurrent sinusitis (HP:0011108)1.73122664
134Pendular nystagmus (HP:0012043)1.72109933
135Preaxial foot polydactyly (HP:0001841)1.70529496
136Abnormal rod and cone electroretinograms (HP:0008323)1.68095235
137Orchitis (HP:0100796)1.67495981
138Absent speech (HP:0001344)1.66931818
139Male pseudohermaphroditism (HP:0000037)1.66303716
140Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.65983970
141Myositis (HP:0100614)1.64845757
142Congenital stationary night blindness (HP:0007642)1.64788915
143Patchy hypopigmentation of hair (HP:0011365)1.64258340
144Disproportionate short-trunk short stature (HP:0003521)1.64237133
145Anencephaly (HP:0002323)1.63636535
146Keratitis (HP:0000491)1.63137574
147Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.63065024
148Aqueductal stenosis (HP:0002410)1.62593404
149Hypoplastic labia majora (HP:0000059)1.61969038
150Drooling (HP:0002307)1.61841810
151Sloping forehead (HP:0000340)1.61597144
152Aplasia cutis congenita (HP:0001057)1.61594327
153Abnormality of the incisor (HP:0000676)1.61372840
154Holoprosencephaly (HP:0001360)1.61079203
155Bronchiectasis (HP:0002110)1.59771488
156Duodenal stenosis (HP:0100867)1.58124766
157Small intestinal stenosis (HP:0012848)1.58124766

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK5.64277789
2MKNK24.00305723
3IRAK32.65987113
4MKNK12.65413026
5PNCK2.49357994
6WNK32.47660397
7LATS12.44328247
8NLK2.41699428
9TRIM282.38787864
10SRPK12.35124268
11CDK32.26377030
12CASK2.23042632
13MAP3K142.12391855
14ZAK2.11574687
15IRAK42.00133259
16TXK1.92964410
17INSRR1.90892285
18PLK21.90880182
19TAOK31.89382158
20WEE11.86347270
21BCR1.84682624
22MAP4K21.82313549
23BRSK21.78293753
24EIF2AK21.68355173
25STK161.66865405
26CDK121.66381866
27MAP2K71.62570207
28TEC1.60631947
29YES11.60261789
30NUAK11.52806200
31BMPR1B1.46748394
32BRD41.45964885
33STK31.43922757
34TLK11.43856773
35STK391.43103247
36MAPK151.40280394
37EIF2AK31.31782386
38EPHA41.31096069
39MST41.31063594
40NEK61.30500366
41OXSR11.28291268
42IRAK11.25597830
43FRK1.23907649
44PLK41.23656139
45IKBKB1.23465190
46ACVR1B1.22861463
47KIT1.22674840
48CDC71.21815018
49ATR1.20619263
50CHUK1.19857681
51SGK21.16076271
52VRK11.12507317
53GRK11.12346464
54IKBKE1.11442847
55JAK31.09298110
56MUSK1.03345257
57PAK31.02299417
58TGFBR11.01822529
59DYRK31.01746175
60MAP3K60.98571555
61CDK90.96874714
62WNK40.89932969
63STK38L0.89385503
64CDK80.89320495
65TTK0.86473741
66PTK2B0.85974960
67PINK10.85699269
68ATM0.82583456
69MAPK130.82023898
70EIF2AK10.79673432
71CAMK1D0.78095462
72BTK0.77290689
73MARK10.77219208
74DYRK20.76933290
75NEK90.75999399
76CSNK1G20.75215357
77NTRK30.74606232
78CSNK1G10.74493931
79CHEK20.74023808
80RPS6KA40.70630562
81PASK0.70054835
82RPS6KB10.69943687
83PRKD20.68914930
84SGK30.67325459
85NEK10.65509403
86AKT30.64753399
87PBK0.64447272
88JAK10.62323631
89LYN0.61217443
90PRKCE0.59204636
91PRKCG0.59030820
92ADRBK20.58975449
93BUB10.58077824
94NTRK20.55454245
95CLK10.54839099
96LCK0.54679391
97AURKB0.53729889
98EPHB20.53692323
99ADRBK10.53451928
100NEK20.52006276
101PRPF4B0.51890464
102ERBB30.50959602
103FES0.50908787
104TIE10.50873345
105TGFBR20.50550288
106PLK10.50188820
107PIM10.49531845
108DYRK1A0.48864381
109TSSK60.47171251
110CAMK1G0.46373662
111BMPR20.44417866
112PKN10.44260419
113TAF10.44057856
114FER0.43989027
115RPS6KA50.43984563
116CHEK10.42906580
117BRSK10.42852804
118PIK3CA0.42827016
119MINK10.42089931
120SYK0.41785999
121ERBB20.41658332
122CDK70.41538012
123MAPK140.41351268
124CSF1R0.41347926
125STK240.40045109
126MELK0.39081278
127CSNK1G30.38066778
128PRKG10.37600401
129IRAK20.36460049
130FGFR20.36082894
131ZAP700.35960307
132PLK30.35956760
133PRKAA20.35471936
134AKT10.35460981
135TYK20.35343855
136PIK3CG0.35253627
137WNK10.34291704
138HIPK20.34167219
139TBK10.34019772
140SGK10.33722911
141FLT30.33225760
142RIPK40.33190146
143CDK10.33030235
144CAMK10.32974390
145CSNK1D0.32768245
146CSNK1A1L0.32749546
147EPHA30.32502392
148CAMK2A0.32047179
149PRKDC0.31990224
150PRKACB0.31792088
151MARK30.31774845
152TRPM70.31165854
153IGF1R0.30931594
154CAMKK20.30673772
155MAP3K40.30651041
156CAMK40.29899688

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.91080425
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.84190653
3Homologous recombination_Homo sapiens_hsa034402.83072557
4Non-homologous end-joining_Homo sapiens_hsa034502.58846330
5Basal transcription factors_Homo sapiens_hsa030222.15644642
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.08196436
7Primary immunodeficiency_Homo sapiens_hsa053402.04595560
8Butanoate metabolism_Homo sapiens_hsa006502.02127942
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.79855218
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.76353463
11Propanoate metabolism_Homo sapiens_hsa006401.72576186
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.71873634
13Measles_Homo sapiens_hsa051621.71676982
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.70065378
15Mismatch repair_Homo sapiens_hsa034301.69556751
16Hedgehog signaling pathway_Homo sapiens_hsa043401.65511907
17Herpes simplex infection_Homo sapiens_hsa051681.64073016
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.60895728
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.60882691
20Steroid biosynthesis_Homo sapiens_hsa001001.59949652
21Protein export_Homo sapiens_hsa030601.56424363
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.52710851
23DNA replication_Homo sapiens_hsa030301.48279819
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.46400606
25Nitrogen metabolism_Homo sapiens_hsa009101.46064862
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.45185701
27Autoimmune thyroid disease_Homo sapiens_hsa053201.45046797
28Primary bile acid biosynthesis_Homo sapiens_hsa001201.44887937
29Hematopoietic cell lineage_Homo sapiens_hsa046401.42851874
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.39418121
31Base excision repair_Homo sapiens_hsa034101.37765206
32RNA degradation_Homo sapiens_hsa030181.36394351
33Linoleic acid metabolism_Homo sapiens_hsa005911.36258631
34Cell cycle_Homo sapiens_hsa041101.36228819
35Nucleotide excision repair_Homo sapiens_hsa034201.34585239
36Olfactory transduction_Homo sapiens_hsa047401.34545913
37Transcriptional misregulation in cancer_Homo sapiens_hsa052021.29777114
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27157949
39Toll-like receptor signaling pathway_Homo sapiens_hsa046201.26645304
40Fatty acid elongation_Homo sapiens_hsa000621.25445395
41Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.24136656
42SNARE interactions in vesicular transport_Homo sapiens_hsa041301.23530633
43Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.21536958
44Leishmaniasis_Homo sapiens_hsa051401.21245131
45Chemical carcinogenesis_Homo sapiens_hsa052041.20893673
46Jak-STAT signaling pathway_Homo sapiens_hsa046301.20544907
47Allograft rejection_Homo sapiens_hsa053301.20093451
48Caffeine metabolism_Homo sapiens_hsa002321.19811938
49Huntingtons disease_Homo sapiens_hsa050161.19183935
50p53 signaling pathway_Homo sapiens_hsa041151.17372359
51Oxidative phosphorylation_Homo sapiens_hsa001901.17316965
52Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.14578386
53Influenza A_Homo sapiens_hsa051641.11766823
54Graft-versus-host disease_Homo sapiens_hsa053321.09664745
55Other glycan degradation_Homo sapiens_hsa005111.09023446
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.05680538
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05407201
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.04391912
59Antigen processing and presentation_Homo sapiens_hsa046121.04242468
60Retinol metabolism_Homo sapiens_hsa008301.02932228
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02010799
62Osteoclast differentiation_Homo sapiens_hsa043800.99161486
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.99014164
64TNF signaling pathway_Homo sapiens_hsa046680.97791159
65One carbon pool by folate_Homo sapiens_hsa006700.97436393
66Phototransduction_Homo sapiens_hsa047440.97365414
67Tryptophan metabolism_Homo sapiens_hsa003800.97172001
68Parkinsons disease_Homo sapiens_hsa050120.96662580
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92631763
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.92468470
71Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.91509256
72Prostate cancer_Homo sapiens_hsa052150.91217606
73Asthma_Homo sapiens_hsa053100.90881915
74Fatty acid degradation_Homo sapiens_hsa000710.90689417
75Circadian entrainment_Homo sapiens_hsa047130.90441874
76Oocyte meiosis_Homo sapiens_hsa041140.86872776
77Glutamatergic synapse_Homo sapiens_hsa047240.86579481
78Arachidonic acid metabolism_Homo sapiens_hsa005900.86005349
79Hepatitis B_Homo sapiens_hsa051610.85574407
80Morphine addiction_Homo sapiens_hsa050320.83894981
81Spliceosome_Homo sapiens_hsa030400.82132754
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.81396345
83B cell receptor signaling pathway_Homo sapiens_hsa046620.80163171
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79359764
85Hippo signaling pathway_Homo sapiens_hsa043900.79298242
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78513063
87Tuberculosis_Homo sapiens_hsa051520.76498634
88Peroxisome_Homo sapiens_hsa041460.75477354
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.75401378
90Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.75071502
91Circadian rhythm_Homo sapiens_hsa047100.74958111
92Epstein-Barr virus infection_Homo sapiens_hsa051690.74600156
93Type I diabetes mellitus_Homo sapiens_hsa049400.74471220
94beta-Alanine metabolism_Homo sapiens_hsa004100.73610523
95Glycerolipid metabolism_Homo sapiens_hsa005610.72176624
96Malaria_Homo sapiens_hsa051440.71035663
97Taste transduction_Homo sapiens_hsa047420.70782792
98Sphingolipid metabolism_Homo sapiens_hsa006000.70266224
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.70048777
100Systemic lupus erythematosus_Homo sapiens_hsa053220.68855907
101Acute myeloid leukemia_Homo sapiens_hsa052210.68842444
102T cell receptor signaling pathway_Homo sapiens_hsa046600.68234720
103N-Glycan biosynthesis_Homo sapiens_hsa005100.67732565
104Rheumatoid arthritis_Homo sapiens_hsa053230.67561047
105Fatty acid metabolism_Homo sapiens_hsa012120.67523312
106Regulation of autophagy_Homo sapiens_hsa041400.66762239
107Selenocompound metabolism_Homo sapiens_hsa004500.65903990
108TGF-beta signaling pathway_Homo sapiens_hsa043500.65291879
109Pyrimidine metabolism_Homo sapiens_hsa002400.65136068
110Fatty acid biosynthesis_Homo sapiens_hsa000610.63946175
111Toxoplasmosis_Homo sapiens_hsa051450.63898592
112Hepatitis C_Homo sapiens_hsa051600.63745605
113Purine metabolism_Homo sapiens_hsa002300.63512810
114Dorso-ventral axis formation_Homo sapiens_hsa043200.63479885
115Viral carcinogenesis_Homo sapiens_hsa052030.63057237
116Glutathione metabolism_Homo sapiens_hsa004800.62362467
117GABAergic synapse_Homo sapiens_hsa047270.62165121
118Ether lipid metabolism_Homo sapiens_hsa005650.60807448
119RNA polymerase_Homo sapiens_hsa030200.60334717
120HTLV-I infection_Homo sapiens_hsa051660.60066130
121mRNA surveillance pathway_Homo sapiens_hsa030150.59877823
122Axon guidance_Homo sapiens_hsa043600.57327936
123Lysine degradation_Homo sapiens_hsa003100.57142962
124Dopaminergic synapse_Homo sapiens_hsa047280.56564326
125Chemokine signaling pathway_Homo sapiens_hsa040620.56050316
126RNA transport_Homo sapiens_hsa030130.55989485
127Prolactin signaling pathway_Homo sapiens_hsa049170.55793270
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.55478795
129Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55261798
130Small cell lung cancer_Homo sapiens_hsa052220.54559107
131Apoptosis_Homo sapiens_hsa042100.53425004
132MicroRNAs in cancer_Homo sapiens_hsa052060.53227303
133Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52918315
134Inositol phosphate metabolism_Homo sapiens_hsa005620.51547607
135Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51500477
136FoxO signaling pathway_Homo sapiens_hsa040680.50543816
137Basal cell carcinoma_Homo sapiens_hsa052170.50012266
138Glycosaminoglycan degradation_Homo sapiens_hsa005310.48251931
139Long-term depression_Homo sapiens_hsa047300.48147822
140Metabolic pathways_Homo sapiens_hsa011000.47145532
141Melanoma_Homo sapiens_hsa052180.46916535
142Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.46656314
143Alzheimers disease_Homo sapiens_hsa050100.46291356
144Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46012960
145Colorectal cancer_Homo sapiens_hsa052100.45473495
146Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45137264
147Legionellosis_Homo sapiens_hsa051340.44931487
148Collecting duct acid secretion_Homo sapiens_hsa049660.43043328
149Pathways in cancer_Homo sapiens_hsa052000.42903951
150Wnt signaling pathway_Homo sapiens_hsa043100.42894005
151Pancreatic cancer_Homo sapiens_hsa052120.42567344
152Serotonergic synapse_Homo sapiens_hsa047260.42129198
153Insulin secretion_Homo sapiens_hsa049110.41187578
154Nicotine addiction_Homo sapiens_hsa050330.39933846
155Alcoholism_Homo sapiens_hsa050340.39560305
156Salivary secretion_Homo sapiens_hsa049700.38376500
157Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.38308658
158Calcium signaling pathway_Homo sapiens_hsa040200.37952374
159ABC transporters_Homo sapiens_hsa020100.37684140
160cAMP signaling pathway_Homo sapiens_hsa040240.37634070
161Histidine metabolism_Homo sapiens_hsa003400.36228687

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