Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.48758377 |
2 | synaptic vesicle maturation (GO:0016188) | 5.48302976 |
3 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.06112262 |
4 | locomotory exploration behavior (GO:0035641) | 4.88873427 |
5 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.67857918 |
6 | glutamate secretion (GO:0014047) | 4.63696733 |
7 | layer formation in cerebral cortex (GO:0021819) | 4.51754162 |
8 | vocalization behavior (GO:0071625) | 4.42637773 |
9 | synaptic vesicle exocytosis (GO:0016079) | 4.29517105 |
10 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.22817634 |
11 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.21698229 |
12 | activation of Rac GTPase activity (GO:0032863) | 4.04610606 |
13 | cell-substrate junction assembly (GO:0007044) | 3.96000617 |
14 | semaphorin-plexin signaling pathway (GO:0071526) | 3.94278447 |
15 | neurotransmitter secretion (GO:0007269) | 3.90468012 |
16 | sodium ion export (GO:0071436) | 3.86664344 |
17 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.77924831 |
18 | adherens junction assembly (GO:0034333) | 3.73549482 |
19 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.71259556 |
20 | proline transport (GO:0015824) | 3.68231236 |
21 | exploration behavior (GO:0035640) | 3.66376104 |
22 | epithelial cell-cell adhesion (GO:0090136) | 3.65945370 |
23 | regulation of synaptic vesicle transport (GO:1902803) | 3.64263972 |
24 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.63899463 |
25 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.62208723 |
26 | cellular potassium ion homeostasis (GO:0030007) | 3.62190954 |
27 | dendritic spine morphogenesis (GO:0060997) | 3.62062576 |
28 | focal adhesion assembly (GO:0048041) | 3.54054750 |
29 | cell-substrate adherens junction assembly (GO:0007045) | 3.54054750 |
30 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.50582719 |
31 | protein localization to endosome (GO:0036010) | 3.41570342 |
32 | activation of protein kinase A activity (GO:0034199) | 3.38633775 |
33 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.38266045 |
34 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.37313291 |
35 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.37210407 |
36 | Golgi transport vesicle coating (GO:0048200) | 3.37050126 |
37 | COPI coating of Golgi vesicle (GO:0048205) | 3.37050126 |
38 | protein retention in ER lumen (GO:0006621) | 3.33125826 |
39 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.27761222 |
40 | regulation of water loss via skin (GO:0033561) | 3.27734858 |
41 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.25166781 |
42 | protein localization to synapse (GO:0035418) | 3.21197691 |
43 | gamma-aminobutyric acid transport (GO:0015812) | 3.18955567 |
44 | cell communication by electrical coupling (GO:0010644) | 3.18355075 |
45 | cerebellar Purkinje cell layer development (GO:0021680) | 3.17900256 |
46 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.17320364 |
47 | neuromuscular process controlling balance (GO:0050885) | 3.11374405 |
48 | positive regulation of synapse maturation (GO:0090129) | 3.11042596 |
49 | regulation of early endosome to late endosome transport (GO:2000641) | 3.08705014 |
50 | negative regulation of cell size (GO:0045792) | 3.08664839 |
51 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.06612040 |
52 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.03795941 |
53 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.03095990 |
54 | establishment of apical/basal cell polarity (GO:0035089) | 3.02355082 |
55 | regulation of synapse structural plasticity (GO:0051823) | 3.01677180 |
56 | neurotransmitter transport (GO:0006836) | 3.00691543 |
57 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.99813237 |
58 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.99795316 |
59 | negative regulation of fatty acid transport (GO:2000192) | 2.98816348 |
60 | dendrite morphogenesis (GO:0048813) | 2.95880793 |
61 | regulation of ARF protein signal transduction (GO:0032012) | 2.95417655 |
62 | neuromuscular process controlling posture (GO:0050884) | 2.95393477 |
63 | cell communication involved in cardiac conduction (GO:0086065) | 2.93780327 |
64 | atrioventricular valve morphogenesis (GO:0003181) | 2.92185919 |
65 | establishment of skin barrier (GO:0061436) | 2.92038943 |
66 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.91753606 |
67 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.88055687 |
68 | endothelial cell chemotaxis (GO:0035767) | 2.87162227 |
69 | chemosensory behavior (GO:0007635) | 2.85063690 |
70 | synaptic vesicle endocytosis (GO:0048488) | 2.84418515 |
71 | vesicle transport along microtubule (GO:0047496) | 2.83961616 |
72 | glycine transport (GO:0015816) | 2.83623093 |
73 | synaptic transmission, glutamatergic (GO:0035249) | 2.80659813 |
74 | dendritic spine organization (GO:0097061) | 2.80129104 |
75 | apoptotic process involved in morphogenesis (GO:0060561) | 2.79080903 |
76 | regulation of neurotransmitter levels (GO:0001505) | 2.76539809 |
77 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.76498185 |
78 | neuronal action potential propagation (GO:0019227) | 2.75405126 |
79 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.75109714 |
80 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.74320697 |
81 | multicellular organismal water homeostasis (GO:0050891) | 2.74136046 |
82 | long-term memory (GO:0007616) | 2.73928216 |
83 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.73660124 |
84 | alanine transport (GO:0032328) | 2.72321443 |
85 | neuron cell-cell adhesion (GO:0007158) | 2.71430094 |
86 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.71429605 |
87 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.70080175 |
88 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.69700505 |
89 | regulation of synaptic plasticity (GO:0048167) | 2.68407253 |
90 | positive regulation of membrane potential (GO:0045838) | 2.67423211 |
91 | lung epithelium development (GO:0060428) | 2.66880788 |
92 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.64942611 |
93 | cell migration in hindbrain (GO:0021535) | 2.64104087 |
94 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.63422906 |
95 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.62428761 |
96 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.62244357 |
97 | regulation of cholesterol homeostasis (GO:2000188) | 2.61955051 |
98 | positive regulation of vesicle fusion (GO:0031340) | 2.61595419 |
99 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.60798414 |
100 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.60061929 |
101 | innervation (GO:0060384) | 2.58338624 |
102 | axonal fasciculation (GO:0007413) | 2.58206671 |
103 | regulation of vesicle fusion (GO:0031338) | 2.57955071 |
104 | neuron-neuron synaptic transmission (GO:0007270) | 2.57711422 |
105 | neuron recognition (GO:0008038) | 2.57448955 |
106 | organelle transport along microtubule (GO:0072384) | 2.57327394 |
107 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.57235753 |
108 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.56370609 |
109 | cellular sodium ion homeostasis (GO:0006883) | 2.55872574 |
110 | glutamate receptor signaling pathway (GO:0007215) | 2.55616382 |
111 | desmosome organization (GO:0002934) | 2.55100478 |
112 | regulation of neurotransmitter secretion (GO:0046928) | 2.54416725 |
113 | cell volume homeostasis (GO:0006884) | 2.54030261 |
114 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.53987204 |
115 | cell junction maintenance (GO:0034331) | 2.53857934 |
116 | cerebellar granule cell differentiation (GO:0021707) | 2.52983379 |
117 | myelin maintenance (GO:0043217) | 2.52895315 |
118 | skin morphogenesis (GO:0043589) | 2.52350704 |
119 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.51758392 |
120 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.50219396 |
121 | potassium ion homeostasis (GO:0055075) | 2.50114613 |
122 | establishment of nucleus localization (GO:0040023) | 2.49031698 |
123 | regulation of postsynaptic membrane potential (GO:0060078) | 2.48961863 |
124 | actin filament bundle assembly (GO:0051017) | 2.47858241 |
125 | actin filament bundle organization (GO:0061572) | 2.47858241 |
126 | apical protein localization (GO:0045176) | 2.47278083 |
127 | intraspecies interaction between organisms (GO:0051703) | 2.47107100 |
128 | social behavior (GO:0035176) | 2.47107100 |
129 | endocytic recycling (GO:0032456) | 2.46533280 |
130 | neuronal ion channel clustering (GO:0045161) | 2.46207517 |
131 | neuromuscular process (GO:0050905) | 2.45401568 |
132 | basement membrane organization (GO:0071711) | 2.45265974 |
133 | regulation of cardioblast differentiation (GO:0051890) | 2.44727985 |
134 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.43950395 |
135 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.43326312 |
136 | mating behavior (GO:0007617) | 2.43045690 |
137 | axon cargo transport (GO:0008088) | 2.41983532 |
138 | negative regulation of catenin import into nucleus (GO:0035414) | 2.41917877 |
139 | auditory behavior (GO:0031223) | 2.41717282 |
140 | protein targeting to plasma membrane (GO:0072661) | 2.41498627 |
141 | membrane repolarization (GO:0086009) | 2.41474439 |
142 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.40897376 |
143 | adherens junction organization (GO:0034332) | 2.40471244 |
144 | proline biosynthetic process (GO:0006561) | 2.40340510 |
145 | hemidesmosome assembly (GO:0031581) | 2.40317880 |
146 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.40299730 |
147 | suckling behavior (GO:0001967) | 2.39249186 |
148 | membrane repolarization during action potential (GO:0086011) | 2.38938023 |
149 | maternal placenta development (GO:0001893) | 2.38850394 |
150 | synapse organization (GO:0050808) | 2.38491496 |
151 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.37951529 |
152 | establishment of monopolar cell polarity (GO:0061162) | 2.37951529 |
153 | amino acid import (GO:0043090) | 2.37809802 |
154 | potassium ion import (GO:0010107) | 2.37375818 |
155 | positive regulation of establishment of protein localization to plasma membrane (GO:0090004) | 2.36507060 |
156 | asymmetric protein localization (GO:0008105) | 2.36360200 |
157 | signal release (GO:0023061) | 2.35756051 |
158 | positive regulation of receptor recycling (GO:0001921) | 2.35525627 |
159 | cell junction assembly (GO:0034329) | 2.35117884 |
160 | prepulse inhibition (GO:0060134) | 2.34976168 |
161 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.34387323 |
162 | response to auditory stimulus (GO:0010996) | 2.34238532 |
163 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.34074292 |
164 | regulation of ARF GTPase activity (GO:0032312) | 2.33380637 |
165 | cell-cell junction maintenance (GO:0045217) | 2.33348017 |
166 | plasma membrane repair (GO:0001778) | 2.32827826 |
167 | negative regulation of hormone metabolic process (GO:0032351) | 2.31818490 |
168 | barbed-end actin filament capping (GO:0051016) | 2.31169247 |
169 | dopamine receptor signaling pathway (GO:0007212) | 2.29450570 |
170 | actin filament depolymerization (GO:0030042) | 2.28609632 |
171 | gap junction assembly (GO:0016264) | 2.27498982 |
172 | regulation of establishment of planar polarity (GO:0090175) | 2.27168382 |
173 | regulation of synapse maturation (GO:0090128) | 2.26993240 |
174 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.26736675 |
175 | receptor catabolic process (GO:0032801) | 2.25825419 |
176 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 2.25446405 |
177 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.25018123 |
178 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.25018123 |
179 | positive regulation of protein localization to plasma membrane (GO:1903078) | 2.24122786 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.81660359 |
2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.55222676 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.81655811 |
4 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.52184641 |
5 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.33992552 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.28819066 |
7 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.21887348 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.17303153 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.17303153 |
10 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.15162994 |
11 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.14923831 |
12 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.10871167 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.09830754 |
14 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.08726883 |
15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.04920885 |
16 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.00481585 |
17 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.94866929 |
18 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.94098644 |
19 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.90715758 |
20 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.87446700 |
21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.82665592 |
22 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.82609368 |
23 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.82410068 |
24 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.81782227 |
25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.81352855 |
26 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.80478424 |
27 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.79754645 |
28 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.78621060 |
29 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.77367660 |
30 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.76896587 |
31 | KDM2B_26808549_Chip-Seq_K562_Human | 1.76775867 |
32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.76620465 |
33 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.66807970 |
34 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.64989274 |
35 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.64165504 |
36 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.63491050 |
37 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.60871957 |
38 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.60273713 |
39 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.58243167 |
40 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.58050149 |
41 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.56811828 |
42 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.56078200 |
43 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.56040860 |
44 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.55326447 |
45 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.53877092 |
46 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.52611321 |
47 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.51141032 |
48 | P68_20966046_ChIP-Seq_HELA_Human | 1.51133002 |
49 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.50800623 |
50 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.49453703 |
51 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.48050111 |
52 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.45732452 |
53 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.43839482 |
54 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.41787868 |
55 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.41214274 |
56 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.39961135 |
57 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.36863588 |
58 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.35732794 |
59 | ATF3_27146783_Chip-Seq_COLON_Human | 1.34766773 |
60 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.34019856 |
61 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.33928629 |
62 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33094511 |
63 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.32936952 |
64 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.32670677 |
65 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.32141000 |
66 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.32047870 |
67 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.29879515 |
68 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.29872731 |
69 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.26170161 |
70 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.24306596 |
71 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.24104340 |
72 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.23092756 |
73 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.22367755 |
74 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.22303979 |
75 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.22049607 |
76 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.21946302 |
77 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.21238074 |
78 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21143612 |
79 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.20885666 |
80 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.20651327 |
81 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.19544574 |
82 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.17081006 |
83 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.17064502 |
84 | AR_19668381_ChIP-Seq_PC3_Human | 1.16449837 |
85 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.15503525 |
86 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.13783532 |
87 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.13471492 |
88 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.11341903 |
89 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.10949994 |
90 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.10249079 |
91 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.09889894 |
92 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.09275388 |
93 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.09048908 |
94 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.09044652 |
95 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.07348011 |
96 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06419148 |
97 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.05757218 |
98 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.05720593 |
99 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.05644131 |
100 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.05388148 |
101 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.04970028 |
102 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.04713621 |
103 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03932934 |
104 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.03394558 |
105 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.01553703 |
106 | RXR_22108803_ChIP-Seq_LS180_Human | 1.01469323 |
107 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.01464962 |
108 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.01050544 |
109 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.00972150 |
110 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.99661026 |
111 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.99262330 |
112 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98773314 |
113 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.98355666 |
114 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.98166006 |
115 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.97874748 |
116 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97637515 |
117 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.97355166 |
118 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.97303584 |
119 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.97289357 |
120 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.97207372 |
121 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.97187222 |
122 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.97097670 |
123 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.96920161 |
124 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.96794044 |
125 | MYC_22102868_ChIP-Seq_BL_Human | 0.96730627 |
126 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.96507980 |
127 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.96466252 |
128 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.95484102 |
129 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.94841090 |
130 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.94792422 |
131 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.94792422 |
132 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.94770434 |
133 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.94712310 |
134 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.94620279 |
135 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.94285242 |
136 | TP53_16413492_ChIP-PET_HCT116_Human | 0.93905349 |
137 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.93407273 |
138 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.92996365 |
139 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.91511942 |
140 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.90247821 |
141 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.88785558 |
142 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.88475853 |
143 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.87307564 |
144 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.87265202 |
145 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.87077174 |
146 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.86058297 |
147 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.85740319 |
148 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.85679768 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.69593951 |
2 | MP0010234_abnormal_vibrissa_follicle | 3.51484929 |
3 | MP0004270_analgesia | 3.45462144 |
4 | MP0003635_abnormal_synaptic_transmissio | 3.28501215 |
5 | MP0009780_abnormal_chondrocyte_physiolo | 2.96190538 |
6 | MP0000566_synostosis | 2.81708325 |
7 | MP0005409_darkened_coat_color | 2.77836952 |
8 | MP0004858_abnormal_nervous_system | 2.61212978 |
9 | MP0003283_abnormal_digestive_organ | 2.57889220 |
10 | MP0002063_abnormal_learning/memory/cond | 2.51325043 |
11 | MP0002909_abnormal_adrenal_gland | 2.36798069 |
12 | MP0003880_abnormal_central_pattern | 2.27943170 |
13 | MP0009745_abnormal_behavioral_response | 2.26538524 |
14 | MP0002249_abnormal_larynx_morphology | 2.26141810 |
15 | MP0009046_muscle_twitch | 2.20883637 |
16 | MP0003453_abnormal_keratinocyte_physiol | 2.20143919 |
17 | MP0003705_abnormal_hypodermis_morpholog | 2.16401747 |
18 | MP0002064_seizures | 2.14211042 |
19 | MP0002734_abnormal_mechanical_nocicepti | 2.06422551 |
20 | MP0008438_abnormal_cutaneous_collagen | 2.05662655 |
21 | MP0003329_amyloid_beta_deposits | 2.01981611 |
22 | MP0002572_abnormal_emotion/affect_behav | 1.98794104 |
23 | MP0005257_abnormal_intraocular_pressure | 1.86807145 |
24 | MP0004272_abnormal_basement_membrane | 1.84655350 |
25 | MP0005423_abnormal_somatic_nervous | 1.83116112 |
26 | MP0002060_abnormal_skin_morphology | 1.82719567 |
27 | MP0002098_abnormal_vibrissa_morphology | 1.79848075 |
28 | MP0001968_abnormal_touch/_nociception | 1.78079402 |
29 | MP0010030_abnormal_orbit_morphology | 1.76665976 |
30 | MP0002822_catalepsy | 1.74539058 |
31 | MP0002796_impaired_skin_barrier | 1.70646416 |
32 | MP0000762_abnormal_tongue_morphology | 1.67222228 |
33 | MP0008961_abnormal_basal_metabolism | 1.67174596 |
34 | MP0003879_abnormal_hair_cell | 1.64489794 |
35 | MP0002733_abnormal_thermal_nociception | 1.63580202 |
36 | MP0001501_abnormal_sleep_pattern | 1.63011501 |
37 | MP0000013_abnormal_adipose_tissue | 1.62574977 |
38 | MP0001486_abnormal_startle_reflex | 1.57669364 |
39 | MP0004885_abnormal_endolymph | 1.56185992 |
40 | MP0004811_abnormal_neuron_physiology | 1.54130420 |
41 | MP0002272_abnormal_nervous_system | 1.51865630 |
42 | MP0001440_abnormal_grooming_behavior | 1.48365918 |
43 | MP0005623_abnormal_meninges_morphology | 1.44042849 |
44 | MP0002184_abnormal_innervation | 1.38141984 |
45 | MP0008569_lethality_at_weaning | 1.38110472 |
46 | MP0005023_abnormal_wound_healing | 1.37730904 |
47 | MP0003122_maternal_imprinting | 1.35092951 |
48 | MP0000579_abnormal_nail_morphology | 1.34752555 |
49 | MP0010678_abnormal_skin_adnexa | 1.34179447 |
50 | MP0001970_abnormal_pain_threshold | 1.33403388 |
51 | MP0000955_abnormal_spinal_cord | 1.32262385 |
52 | MP0001216_abnormal_epidermal_layer | 1.31854920 |
53 | MP0005058_abnormal_lysosome_morphology | 1.30612907 |
54 | MP0002234_abnormal_pharynx_morphology | 1.30354896 |
55 | MP0000537_abnormal_urethra_morphology | 1.30237636 |
56 | MP0002557_abnormal_social/conspecific_i | 1.29204562 |
57 | MP0003045_fibrosis | 1.27188250 |
58 | MP0000569_abnormal_digit_pigmentation | 1.25867849 |
59 | MP0001958_emphysema | 1.25760251 |
60 | MP0005275_abnormal_skin_tensile | 1.24903568 |
61 | MP0002877_abnormal_melanocyte_morpholog | 1.24036343 |
62 | MP0003091_abnormal_cell_migration | 1.21829660 |
63 | MP0000778_abnormal_nervous_system | 1.21674806 |
64 | MP0005360_urolithiasis | 1.20170672 |
65 | MP0004185_abnormal_adipocyte_glucose | 1.16570853 |
66 | MP0004782_abnormal_surfactant_physiolog | 1.16570369 |
67 | MP0003279_aneurysm | 1.16145058 |
68 | MP0008260_abnormal_autophagy | 1.13698882 |
69 | MP0009840_abnormal_foam_cell | 1.13067184 |
70 | MP0001299_abnormal_eye_distance/ | 1.11884091 |
71 | MP0002735_abnormal_chemical_nociception | 1.11438892 |
72 | MP0001849_ear_inflammation | 1.10902050 |
73 | MP0005451_abnormal_body_composition | 1.06919612 |
74 | MP0002067_abnormal_sensory_capabilities | 1.06591882 |
75 | MP0005187_abnormal_penis_morphology | 1.06494989 |
76 | MP0003787_abnormal_imprinting | 1.05681757 |
77 | MP0002882_abnormal_neuron_morphology | 1.05014202 |
78 | MP0005670_abnormal_white_adipose | 1.04222016 |
79 | MP0000534_abnormal_ureter_morphology | 1.02160909 |
80 | MP0000733_abnormal_muscle_development | 1.01824256 |
81 | MP0005375_adipose_tissue_phenotype | 1.01575792 |
82 | MP0002736_abnormal_nociception_after | 1.00655369 |
83 | MP0000377_abnormal_hair_follicle | 0.99739937 |
84 | MP0005386_behavior/neurological_phenoty | 0.99414239 |
85 | MP0004924_abnormal_behavior | 0.99414239 |
86 | MP0004233_abnormal_muscle_weight | 0.99303049 |
87 | MP0001177_atelectasis | 0.98674988 |
88 | MP0002066_abnormal_motor_capabilities/c | 0.97858219 |
89 | MP0005666_abnormal_adipose_tissue | 0.97685478 |
90 | MP0002896_abnormal_bone_mineralization | 0.95682868 |
91 | MP0005076_abnormal_cell_differentiation | 0.95542985 |
92 | MP0009384_cardiac_valve_regurgitation | 0.95077431 |
93 | MP0003633_abnormal_nervous_system | 0.93417307 |
94 | MP0003119_abnormal_digestive_system | 0.93279323 |
95 | MP0000383_abnormal_hair_follicle | 0.92401099 |
96 | MP0001348_abnormal_lacrimal_gland | 0.92269137 |
97 | MP0000003_abnormal_adipose_tissue | 0.91983054 |
98 | MP0003634_abnormal_glial_cell | 0.90074747 |
99 | MP0002152_abnormal_brain_morphology | 0.89119565 |
100 | MP0003191_abnormal_cellular_cholesterol | 0.88578078 |
101 | MP0004043_abnormal_pH_regulation | 0.85143117 |
102 | MP0005508_abnormal_skeleton_morphology | 0.84898495 |
103 | MP0004264_abnormal_extraembryonic_tissu | 0.84258521 |
104 | MP0003942_abnormal_urinary_system | 0.83827949 |
105 | MP0002069_abnormal_eating/drinking_beha | 0.82594947 |
106 | MP0002089_abnormal_postnatal_growth/wei | 0.82136735 |
107 | MP0005501_abnormal_skin_physiology | 0.81807961 |
108 | MP0000467_abnormal_esophagus_morphology | 0.81704929 |
109 | MP0003631_nervous_system_phenotype | 0.81097253 |
110 | MP0010386_abnormal_urinary_bladder | 0.80605073 |
111 | MP0003566_abnormal_cell_adhesion | 0.80569247 |
112 | MP0005645_abnormal_hypothalamus_physiol | 0.80280632 |
113 | MP0005646_abnormal_pituitary_gland | 0.80127394 |
114 | MP0001664_abnormal_digestion | 0.80081634 |
115 | MP0000604_amyloidosis | 0.79951757 |
116 | MP0003941_abnormal_skin_development | 0.79107985 |
117 | MP0001502_abnormal_circadian_rhythm | 0.79097818 |
118 | MP0006276_abnormal_autonomic_nervous | 0.77504863 |
119 | MP0001984_abnormal_olfaction | 0.77439309 |
120 | MP0003075_altered_response_to | 0.77028185 |
121 | MP0003115_abnormal_respiratory_system | 0.76739358 |
122 | MP0000681_abnormal_thyroid_gland | 0.76569101 |
123 | MP0003632_abnormal_nervous_system | 0.75826797 |
124 | MP0009931_abnormal_skin_appearance | 0.75773362 |
125 | MP0003172_abnormal_lysosome_physiology | 0.75699995 |
126 | MP0000627_abnormal_mammary_gland | 0.75159898 |
127 | MP0000678_abnormal_parathyroid_gland | 0.74709302 |
128 | MP0004947_skin_inflammation | 0.74588122 |
129 | MP0006138_congestive_heart_failure | 0.74404678 |
130 | MP0004381_abnormal_hair_follicle | 0.73978267 |
131 | MP0000751_myopathy | 0.72775145 |
132 | MP0009379_abnormal_foot_pigmentation | 0.71581023 |
133 | MP0005248_abnormal_Harderian_gland | 0.71114494 |
134 | MP0005394_taste/olfaction_phenotype | 0.70504196 |
135 | MP0005499_abnormal_olfactory_system | 0.70504196 |
136 | MP0001346_abnormal_lacrimal_gland | 0.70101798 |
137 | MP0001944_abnormal_pancreas_morphology | 0.69736305 |
138 | MP0010771_integument_phenotype | 0.69467877 |
139 | MP0010352_gastrointestinal_tract_polyps | 0.69408918 |
140 | MP0000462_abnormal_digestive_system | 0.67535903 |
141 | MP0003123_paternal_imprinting | 0.66807150 |
142 | MP0000767_abnormal_smooth_muscle | 0.66558115 |
143 | MP0002116_abnormal_craniofacial_bone | 0.66397258 |
144 | MP0009053_abnormal_anal_canal | 0.65441406 |
145 | MP0002254_reproductive_system_inflammat | 0.65410535 |
146 | MP0008874_decreased_physiological_sensi | 0.65377383 |
147 | MP0008872_abnormal_physiological_respon | 0.65150394 |
148 | MP0002090_abnormal_vision | 0.64534543 |
149 | MP0005503_abnormal_tendon_morphology | 0.63731012 |
150 | MP0000538_abnormal_urinary_bladder | 0.59951276 |
151 | MP0010368_abnormal_lymphatic_system | 0.59754768 |
152 | MP0005621_abnormal_cell_physiology | 0.56936919 |
153 | MP0001765_abnormal_ion_homeostasis | 0.56799041 |
154 | MP0001243_abnormal_dermal_layer | 0.56112261 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 4.41230696 |
2 | Visual hallucinations (HP:0002367) | 3.89903390 |
3 | Focal motor seizures (HP:0011153) | 3.83676345 |
4 | Focal seizures (HP:0007359) | 3.65010622 |
5 | Broad face (HP:0000283) | 3.28125060 |
6 | Abnormality of the lower motor neuron (HP:0002366) | 3.22389337 |
7 | Protrusio acetabuli (HP:0003179) | 3.21844798 |
8 | Premature rupture of membranes (HP:0001788) | 3.13266893 |
9 | Distal lower limb amyotrophy (HP:0008944) | 3.08024927 |
10 | Action tremor (HP:0002345) | 2.97131715 |
11 | Ankle clonus (HP:0011448) | 2.96285519 |
12 | Supranuclear gaze palsy (HP:0000605) | 2.90361516 |
13 | Thin bony cortex (HP:0002753) | 2.75666347 |
14 | Progressive cerebellar ataxia (HP:0002073) | 2.74532732 |
15 | Pili torti (HP:0003777) | 2.65445513 |
16 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.63239327 |
17 | Ulnar bowing (HP:0003031) | 2.62843792 |
18 | Ventricular fibrillation (HP:0001663) | 2.62391250 |
19 | Flat acetabular roof (HP:0003180) | 2.61858979 |
20 | Cervical subluxation (HP:0003308) | 2.59884134 |
21 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.59034386 |
22 | Stridor (HP:0010307) | 2.58562935 |
23 | Upper limb amyotrophy (HP:0009129) | 2.52891911 |
24 | Distal upper limb amyotrophy (HP:0007149) | 2.52891911 |
25 | Absence seizures (HP:0002121) | 2.52778648 |
26 | Bronchomalacia (HP:0002780) | 2.51994719 |
27 | Epileptic encephalopathy (HP:0200134) | 2.49791226 |
28 | Genetic anticipation (HP:0003743) | 2.49472029 |
29 | Cerebral inclusion bodies (HP:0100314) | 2.48665658 |
30 | Generalized tonic-clonic seizures (HP:0002069) | 2.47986619 |
31 | Papilledema (HP:0001085) | 2.46969760 |
32 | Atonic seizures (HP:0010819) | 2.44553065 |
33 | Depression (HP:0000716) | 2.43889024 |
34 | Short nail (HP:0001799) | 2.42853102 |
35 | Hand muscle atrophy (HP:0009130) | 2.42673249 |
36 | Spinal cord compression (HP:0002176) | 2.40669554 |
37 | Ankyloglossia (HP:0010296) | 2.40018328 |
38 | Distal lower limb muscle weakness (HP:0009053) | 2.38691052 |
39 | Postural instability (HP:0002172) | 2.38682436 |
40 | Right ventricular cardiomyopathy (HP:0011663) | 2.36380947 |
41 | Insomnia (HP:0100785) | 2.33981406 |
42 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.33570107 |
43 | Advanced eruption of teeth (HP:0006288) | 2.31880692 |
44 | Dysdiadochokinesis (HP:0002075) | 2.29792749 |
45 | Torticollis (HP:0000473) | 2.27993690 |
46 | Increased connective tissue (HP:0009025) | 2.27158657 |
47 | J-shaped sella turcica (HP:0002680) | 2.24094983 |
48 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.23104597 |
49 | Turricephaly (HP:0000262) | 2.23102819 |
50 | Impaired social interactions (HP:0000735) | 2.21712287 |
51 | Abnormal social behavior (HP:0012433) | 2.21712287 |
52 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.21556904 |
53 | Dysmetric saccades (HP:0000641) | 2.21375220 |
54 | Atrophic scars (HP:0001075) | 2.20239532 |
55 | Hemiplegia (HP:0002301) | 2.18123578 |
56 | Alopecia of scalp (HP:0002293) | 2.16132761 |
57 | Abnormality of nail color (HP:0100643) | 2.14625236 |
58 | Megalencephaly (HP:0001355) | 2.13615277 |
59 | Poor eye contact (HP:0000817) | 2.13152802 |
60 | Pterygium (HP:0001059) | 2.13119270 |
61 | Macroorchidism (HP:0000053) | 2.12190923 |
62 | Hyperacusis (HP:0010780) | 2.12034334 |
63 | Plantar hyperkeratosis (HP:0007556) | 2.09573006 |
64 | Obstructive sleep apnea (HP:0002870) | 2.09309088 |
65 | Dialeptic seizures (HP:0011146) | 2.09240635 |
66 | Shallow orbits (HP:0000586) | 2.07732486 |
67 | Achilles tendon contracture (HP:0001771) | 2.05670131 |
68 | Bladder diverticulum (HP:0000015) | 2.05596957 |
69 | Axonal loss (HP:0003447) | 2.05182183 |
70 | Spinal rigidity (HP:0003306) | 2.03374755 |
71 | Hypercortisolism (HP:0001578) | 2.02979138 |
72 | Natal tooth (HP:0000695) | 2.02703329 |
73 | Agitation (HP:0000713) | 2.01889969 |
74 | Milia (HP:0001056) | 2.00329873 |
75 | Hyperparathyroidism (HP:0000843) | 1.99650895 |
76 | Intention tremor (HP:0002080) | 1.99542052 |
77 | Febrile seizures (HP:0002373) | 1.99251832 |
78 | Pointed chin (HP:0000307) | 1.98897223 |
79 | Selective tooth agenesis (HP:0001592) | 1.98697148 |
80 | Impaired smooth pursuit (HP:0007772) | 1.98581944 |
81 | Urinary urgency (HP:0000012) | 1.98491761 |
82 | Difficulty climbing stairs (HP:0003551) | 1.98394844 |
83 | Abnormal hair laboratory examination (HP:0003328) | 1.98095459 |
84 | Lower limb amyotrophy (HP:0007210) | 1.96933992 |
85 | Mutism (HP:0002300) | 1.96552606 |
86 | Abnormality of the Achilles tendon (HP:0005109) | 1.96177312 |
87 | Cerebral aneurysm (HP:0004944) | 1.95895687 |
88 | Arterial tortuosity (HP:0005116) | 1.95869417 |
89 | Termporal pattern (HP:0011008) | 1.95647192 |
90 | Insidious onset (HP:0003587) | 1.95647192 |
91 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.95154869 |
92 | Focal dystonia (HP:0004373) | 1.93696387 |
93 | Broad metatarsal (HP:0001783) | 1.93001627 |
94 | Neurofibrillary tangles (HP:0002185) | 1.91662611 |
95 | EEG with generalized epileptiform discharges (HP:0011198) | 1.90478710 |
96 | Amblyopia (HP:0000646) | 1.90183888 |
97 | Truncal ataxia (HP:0002078) | 1.89655157 |
98 | Hypoplasia of dental enamel (HP:0006297) | 1.89481312 |
99 | Elfin facies (HP:0004428) | 1.89269646 |
100 | Long palpebral fissure (HP:0000637) | 1.89041169 |
101 | Hypsarrhythmia (HP:0002521) | 1.87868739 |
102 | Acanthosis nigricans (HP:0000956) | 1.87843011 |
103 | Epileptiform EEG discharges (HP:0011182) | 1.87475649 |
104 | Bundle branch block (HP:0011710) | 1.87307578 |
105 | Nail dystrophy (HP:0008404) | 1.87044846 |
106 | Mitral regurgitation (HP:0001653) | 1.87011005 |
107 | Abnormal eating behavior (HP:0100738) | 1.86258993 |
108 | Hypoventilation (HP:0002791) | 1.85754722 |
109 | Vascular tortuosity (HP:0004948) | 1.85656803 |
110 | Dysmetria (HP:0001310) | 1.83817774 |
111 | Onycholysis (HP:0001806) | 1.83460995 |
112 | Resting tremor (HP:0002322) | 1.83130523 |
113 | Anxiety (HP:0000739) | 1.82860686 |
114 | Lymphangioma (HP:0100764) | 1.81668993 |
115 | Intellectual disability, profound (HP:0002187) | 1.81347902 |
116 | Fragile nails (HP:0001808) | 1.81322158 |
117 | Craniofacial dystonia (HP:0012179) | 1.80000068 |
118 | Abnormality of oral frenula (HP:0000190) | 1.78922767 |
119 | Aplasia involving bones of the extremities (HP:0009825) | 1.78874716 |
120 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.78874716 |
121 | Aplasia of the phalanges of the hand (HP:0009802) | 1.78874716 |
122 | Wormian bones (HP:0002645) | 1.78506014 |
123 | Neoplasm of the heart (HP:0100544) | 1.77474528 |
124 | Disproportionate tall stature (HP:0001519) | 1.76115259 |
125 | Nuclear cataract (HP:0100018) | 1.75880635 |
126 | Vertebral compression fractures (HP:0002953) | 1.74092223 |
127 | Thick nail (HP:0001805) | 1.73569059 |
128 | Neonatal death (HP:0003811) | 1.73325502 |
129 | Enlarged penis (HP:0000040) | 1.73304220 |
130 | Drooling (HP:0002307) | 1.73085263 |
131 | Excessive salivation (HP:0003781) | 1.73085263 |
132 | Ankle contracture (HP:0006466) | 1.73054913 |
133 | Status epilepticus (HP:0002133) | 1.72928041 |
134 | Bradykinesia (HP:0002067) | 1.70828420 |
135 | Bowel diverticulosis (HP:0005222) | 1.70408767 |
136 | Spastic gait (HP:0002064) | 1.69811874 |
137 | Atelectasis (HP:0100750) | 1.69754293 |
138 | Aneurysm (HP:0002617) | 1.68876344 |
139 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.68766401 |
140 | Abnormality of carpal bone ossification (HP:0006257) | 1.68161015 |
141 | Hemorrhage of the eye (HP:0011885) | 1.68157964 |
142 | Germ cell neoplasia (HP:0100728) | 1.68104572 |
143 | Overgrowth (HP:0001548) | 1.67223006 |
144 | Rapidly progressive (HP:0003678) | 1.67172839 |
145 | Gaze-evoked nystagmus (HP:0000640) | 1.65932436 |
146 | Neonatal short-limb short stature (HP:0008921) | 1.65787928 |
147 | Abnormal ossification of hand bones (HP:0005921) | 1.65363855 |
148 | Abnormality of the salivary glands (HP:0010286) | 1.65199280 |
149 | Blue sclerae (HP:0000592) | 1.65184147 |
150 | Annular pancreas (HP:0001734) | 1.64981862 |
151 | Clonus (HP:0002169) | 1.64903285 |
152 | Postural tremor (HP:0002174) | 1.64280979 |
153 | Arnold-Chiari malformation (HP:0002308) | 1.63577785 |
154 | Congenital glaucoma (HP:0001087) | 1.63171530 |
155 | Overriding aorta (HP:0002623) | 1.63124394 |
156 | Broad-based gait (HP:0002136) | 1.63102816 |
157 | Fragile skin (HP:0001030) | 1.62797361 |
158 | Scanning speech (HP:0002168) | 1.62733587 |
159 | Buphthalmos (HP:0000557) | 1.62380419 |
160 | Stereotypic behavior (HP:0000733) | 1.62038335 |
161 | Urethral obstruction (HP:0000796) | 1.61668338 |
162 | Premature skin wrinkling (HP:0100678) | 1.60868338 |
163 | Long toe (HP:0010511) | 1.60397377 |
164 | Focal segmental glomerulosclerosis (HP:0000097) | 1.60226107 |
165 | Bowed forearm bones (HP:0003956) | 1.58126083 |
166 | Bowing of the arm (HP:0006488) | 1.58126083 |
167 | Distal sensory impairment (HP:0002936) | 1.58110836 |
168 | Precocious puberty (HP:0000826) | 1.57566733 |
169 | Abnormality of dentin (HP:0010299) | 1.55775926 |
170 | Genu recurvatum (HP:0002816) | 1.55616962 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K9 | 4.08971252 |
2 | NTRK3 | 3.33499426 |
3 | SMG1 | 2.91425042 |
4 | PRKD3 | 2.83599130 |
5 | MARK1 | 2.51997284 |
6 | EPHA4 | 2.47011593 |
7 | RIPK1 | 2.40659776 |
8 | MAP3K4 | 2.36826756 |
9 | PAK6 | 2.33361849 |
10 | IRAK3 | 2.31245036 |
11 | NTRK1 | 2.29323470 |
12 | LATS2 | 2.27342998 |
13 | MINK1 | 2.17624986 |
14 | DAPK2 | 2.16274037 |
15 | MAP3K2 | 2.14905292 |
16 | MET | 2.06232522 |
17 | KSR2 | 2.03144999 |
18 | TRIB3 | 1.93282636 |
19 | TAOK1 | 1.83149680 |
20 | CAMKK1 | 1.82466442 |
21 | STK38 | 1.77446541 |
22 | NTRK2 | 1.64417506 |
23 | PRPF4B | 1.60760429 |
24 | MAP2K4 | 1.56939657 |
25 | TESK1 | 1.56933511 |
26 | TYRO3 | 1.55935124 |
27 | EPHA2 | 1.50354124 |
28 | CDK12 | 1.43932216 |
29 | FER | 1.43129518 |
30 | DDR2 | 1.40351021 |
31 | PDGFRA | 1.38283993 |
32 | PAK4 | 1.32058421 |
33 | PAK3 | 1.30014605 |
34 | TTN | 1.26326246 |
35 | KSR1 | 1.22663611 |
36 | FGFR4 | 1.22150059 |
37 | PTK2 | 1.21823319 |
38 | CDK5 | 1.20959871 |
39 | RET | 1.20723314 |
40 | PKN2 | 1.17960520 |
41 | ALK | 1.17746039 |
42 | LATS1 | 1.17460830 |
43 | MAP2K7 | 1.10504710 |
44 | PRKCH | 0.99456131 |
45 | SCYL2 | 0.99002135 |
46 | ICK | 0.97910223 |
47 | STK11 | 0.95589657 |
48 | LMTK2 | 0.93912498 |
49 | DAPK1 | 0.93182788 |
50 | CAMK1D | 0.91685262 |
51 | SIK2 | 0.91554051 |
52 | UHMK1 | 0.91129469 |
53 | BMX | 0.90508661 |
54 | CDC42BPA | 0.90257433 |
55 | GRK5 | 0.90214395 |
56 | MAP3K1 | 0.89519514 |
57 | NEK1 | 0.86352035 |
58 | MAPKAPK3 | 0.84566187 |
59 | PTK6 | 0.84329754 |
60 | FRK | 0.83675080 |
61 | PRKG2 | 0.83643448 |
62 | MARK2 | 0.79494103 |
63 | NME2 | 0.79477667 |
64 | EPHB2 | 0.77330713 |
65 | PRKCG | 0.77271070 |
66 | MAP3K6 | 0.76474433 |
67 | MAP2K1 | 0.73294742 |
68 | EEF2K | 0.72972276 |
69 | IRAK2 | 0.72782466 |
70 | MAP3K11 | 0.72714603 |
71 | EPHB1 | 0.72689956 |
72 | MAP3K3 | 0.72644233 |
73 | MAP3K13 | 0.71926300 |
74 | MAP3K7 | 0.71694384 |
75 | SGK3 | 0.69691992 |
76 | SIK1 | 0.68576732 |
77 | PLK2 | 0.68510412 |
78 | DMPK | 0.66608871 |
79 | CAMK1G | 0.66339808 |
80 | CDK15 | 0.66038575 |
81 | WNK3 | 0.65790102 |
82 | CDK18 | 0.64078917 |
83 | NEK6 | 0.64029286 |
84 | MAP3K12 | 0.64025384 |
85 | CDK14 | 0.63846915 |
86 | TAOK2 | 0.63679400 |
87 | CAMK1 | 0.62032388 |
88 | PHKG1 | 0.60193246 |
89 | PHKG2 | 0.60193246 |
90 | MAPK15 | 0.59804367 |
91 | ARAF | 0.59592826 |
92 | RPS6KA2 | 0.58409084 |
93 | MAP3K10 | 0.57355145 |
94 | ERN1 | 0.56444685 |
95 | BRAF | 0.56378274 |
96 | CAMK2G | 0.55680807 |
97 | SGK494 | 0.55488555 |
98 | SGK223 | 0.55488555 |
99 | WNK1 | 0.55200733 |
100 | CSNK1G2 | 0.54725135 |
101 | CAMK2A | 0.54723198 |
102 | CDK11A | 0.54589720 |
103 | MTOR | 0.51367907 |
104 | SGK1 | 0.50800701 |
105 | PRKCZ | 0.50602372 |
106 | CAMKK2 | 0.49468146 |
107 | PDPK1 | 0.48847051 |
108 | MST1R | 0.48295375 |
109 | FGFR2 | 0.46994017 |
110 | FGFR1 | 0.46935928 |
111 | PIM2 | 0.46715376 |
112 | RPS6KA3 | 0.46100803 |
113 | PNCK | 0.45213105 |
114 | ILK | 0.44816223 |
115 | PRKD2 | 0.44664289 |
116 | ROCK1 | 0.44228394 |
117 | PAK2 | 0.42841578 |
118 | INSRR | 0.42421795 |
119 | ERBB2 | 0.42071247 |
120 | HIPK2 | 0.42024241 |
121 | MAP2K2 | 0.41770025 |
122 | CSNK1E | 0.41064055 |
123 | PDGFRB | 0.40602222 |
124 | RPS6KB2 | 0.39959532 |
125 | SGK2 | 0.39633195 |
126 | LIMK1 | 0.39514159 |
127 | WNK4 | 0.38792282 |
128 | RPS6KC1 | 0.38688194 |
129 | RPS6KL1 | 0.38688194 |
130 | PRKCI | 0.38226212 |
131 | DAPK3 | 0.38003873 |
132 | MAP2K6 | 0.37991987 |
133 | PDK1 | 0.37552893 |
134 | MAPK10 | 0.36497849 |
135 | CAMK2B | 0.36170658 |
136 | ROCK2 | 0.32925579 |
137 | MUSK | 0.31649593 |
138 | ABL2 | 0.31057651 |
139 | MAPK8 | 0.30648518 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.73261470 |
2 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.41022980 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.18388345 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.13705245 |
5 | Insulin secretion_Homo sapiens_hsa04911 | 2.06791604 |
6 | Long-term potentiation_Homo sapiens_hsa04720 | 1.98308766 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 1.98210123 |
8 | Circadian entrainment_Homo sapiens_hsa04713 | 1.96100465 |
9 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.92525622 |
10 | Olfactory transduction_Homo sapiens_hsa04740 | 1.88211884 |
11 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.85664072 |
12 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.82537531 |
13 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.78689210 |
14 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.72799412 |
15 | Salivary secretion_Homo sapiens_hsa04970 | 1.72205317 |
16 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.71859554 |
17 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.70190150 |
18 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.69980688 |
19 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.64700726 |
20 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.59865865 |
21 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.58910794 |
22 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.53576456 |
23 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.53506842 |
24 | Morphine addiction_Homo sapiens_hsa05032 | 1.51504467 |
25 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.48549938 |
26 | Cocaine addiction_Homo sapiens_hsa05030 | 1.46652669 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.41681023 |
28 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.41018072 |
29 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.34299173 |
30 | Glioma_Homo sapiens_hsa05214 | 1.30498076 |
31 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.29261781 |
32 | Gap junction_Homo sapiens_hsa04540 | 1.28376427 |
33 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.26174520 |
34 | Renin secretion_Homo sapiens_hsa04924 | 1.24811854 |
35 | Taste transduction_Homo sapiens_hsa04742 | 1.23033843 |
36 | Long-term depression_Homo sapiens_hsa04730 | 1.21296113 |
37 | Other glycan degradation_Homo sapiens_hsa00511 | 1.16778296 |
38 | Bile secretion_Homo sapiens_hsa04976 | 1.16707199 |
39 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.16599306 |
40 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.16447337 |
41 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.15979938 |
42 | Melanogenesis_Homo sapiens_hsa04916 | 1.13489123 |
43 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.10529299 |
44 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.09269343 |
45 | Thyroid cancer_Homo sapiens_hsa05216 | 1.07606106 |
46 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.05779186 |
47 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.04677900 |
48 | Axon guidance_Homo sapiens_hsa04360 | 1.04631966 |
49 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.04099326 |
50 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.03788405 |
51 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.02859485 |
52 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.01326860 |
53 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.01195676 |
54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.00990705 |
55 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.99668230 |
56 | Endometrial cancer_Homo sapiens_hsa05213 | 0.99122065 |
57 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.98351158 |
58 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.98314351 |
59 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.97611743 |
60 | Histidine metabolism_Homo sapiens_hsa00340 | 0.95725931 |
61 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.95658397 |
62 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.93002511 |
63 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.91671481 |
64 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.90368221 |
65 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87172613 |
66 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.86918040 |
67 | Galactose metabolism_Homo sapiens_hsa00052 | 0.86380159 |
68 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.82712723 |
69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.82352424 |
70 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.82175331 |
71 | Tight junction_Homo sapiens_hsa04530 | 0.81415515 |
72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.79300031 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.79080826 |
74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79058532 |
75 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.77700068 |
76 | Bladder cancer_Homo sapiens_hsa05219 | 0.77193496 |
77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.76565403 |
78 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.76448320 |
79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.75896027 |
80 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.75785562 |
81 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.75715509 |
82 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.75572301 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.73908831 |
84 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.73508721 |
85 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.72892773 |
86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.71768406 |
87 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69670103 |
88 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.69488002 |
89 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.69459985 |
90 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.68504582 |
91 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.68488579 |
92 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.67768592 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.66670694 |
94 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65250868 |
95 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.65021548 |
96 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.63419945 |
97 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.63047497 |
98 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.61345694 |
99 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.60936683 |
100 | Focal adhesion_Homo sapiens_hsa04510 | 0.60660671 |
101 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.60092686 |
102 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.59947916 |
103 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.59535353 |
104 | Lysine degradation_Homo sapiens_hsa00310 | 0.59514795 |
105 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59273131 |
106 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.59182776 |
107 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.58051257 |
108 | Hepatitis C_Homo sapiens_hsa05160 | 0.57702143 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.57483736 |
110 | Adherens junction_Homo sapiens_hsa04520 | 0.57170314 |
111 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.56670061 |
112 | Amoebiasis_Homo sapiens_hsa05146 | 0.56577817 |
113 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.55907526 |
114 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.55631856 |
115 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.55130094 |
116 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.54733101 |
117 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.54483358 |
118 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.52761955 |
119 | Prion diseases_Homo sapiens_hsa05020 | 0.52594102 |
120 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.52488989 |
121 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.52103812 |
122 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.51660775 |
123 | Mineral absorption_Homo sapiens_hsa04978 | 0.48171419 |
124 | Insulin resistance_Homo sapiens_hsa04931 | 0.46735032 |
125 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44972007 |
126 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.42118613 |
127 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.39983047 |
128 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39828548 |
129 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.39759311 |
130 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.39660875 |
131 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.39580192 |