CEP295

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.40600410
2mitotic sister chromatid cohesion (GO:0007064)5.38881423
3kinetochore organization (GO:0051383)5.29729994
4nuclear pore organization (GO:0006999)5.11318243
5microtubule polymerization or depolymerization (GO:0031109)4.79368591
6protein localization to kinetochore (GO:0034501)4.73922459
7regulation of DNA endoreduplication (GO:0032875)4.71005154
8kinetochore assembly (GO:0051382)4.41704076
9meiotic chromosome segregation (GO:0045132)4.34916745
10sister chromatid segregation (GO:0000819)4.27621251
11protein localization to chromosome, centromeric region (GO:0071459)4.25498086
12mitotic chromosome condensation (GO:0007076)4.21458693
13pore complex assembly (GO:0046931)4.18919036
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.18002302
15chromatin remodeling at centromere (GO:0031055)4.17360228
16DNA unwinding involved in DNA replication (GO:0006268)4.13573622
17CENP-A containing nucleosome assembly (GO:0034080)4.11273065
18mitotic sister chromatid segregation (GO:0000070)4.07960446
19mitotic metaphase plate congression (GO:0007080)4.00553796
20establishment of protein localization to Golgi (GO:0072600)3.97863745
21regulation of histone H3-K9 methylation (GO:0051570)3.93475417
22regulation of centriole replication (GO:0046599)3.91159707
23metaphase plate congression (GO:0051310)3.90968005
24negative regulation of DNA-dependent DNA replication (GO:2000104)3.90748032
25spermatid nucleus differentiation (GO:0007289)3.84372727
26DNA replication-independent nucleosome assembly (GO:0006336)3.82244893
27DNA replication-independent nucleosome organization (GO:0034724)3.82244893
28centrosome organization (GO:0051297)3.73038485
29protein targeting to Golgi (GO:0000042)3.71044156
30synapsis (GO:0007129)3.69695816
31histone exchange (GO:0043486)3.69339081
32DNA topological change (GO:0006265)3.68092011
33attachment of spindle microtubules to kinetochore (GO:0008608)3.66264616
34microtubule depolymerization (GO:0007019)3.62291700
35protein K6-linked ubiquitination (GO:0085020)3.61531192
36mitotic G2/M transition checkpoint (GO:0044818)3.61239614
37DNA duplex unwinding (GO:0032508)3.60546875
38DNA geometric change (GO:0032392)3.60506660
39microtubule organizing center organization (GO:0031023)3.59809104
40DNA replication checkpoint (GO:0000076)3.58172430
41retrograde transport, vesicle recycling within Golgi (GO:0000301)3.54072685
42regulation of RNA export from nucleus (GO:0046831)3.53733947
43DNA replication initiation (GO:0006270)3.51084054
44sperm motility (GO:0030317)3.50919610
45negative regulation of histone methylation (GO:0031061)3.49308030
46double-strand break repair via homologous recombination (GO:0000724)3.48728530
47centrosome duplication (GO:0051298)3.48511279
48mitotic nuclear envelope disassembly (GO:0007077)3.48194257
49recombinational repair (GO:0000725)3.46593786
50regulation of nuclear cell cycle DNA replication (GO:0033262)3.45220683
51nucleotide-excision repair, DNA gap filling (GO:0006297)3.40985740
52microtubule anchoring (GO:0034453)3.39830995
53establishment of chromosome localization (GO:0051303)3.38067891
54single strand break repair (GO:0000012)3.37329470
55chromatin assembly or disassembly (GO:0006333)3.35039691
56mitotic recombination (GO:0006312)3.34924389
57centriole replication (GO:0007099)3.32029778
58response to pheromone (GO:0019236)3.31397712
59sister chromatid cohesion (GO:0007062)3.29716052
60intra-S DNA damage checkpoint (GO:0031573)3.28896576
61regulation of mitotic spindle organization (GO:0060236)3.28301292
62regulation of spindle organization (GO:0090224)3.26686732
63maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.26387101
64protein K11-linked deubiquitination (GO:0035871)3.24128196
65DNA conformation change (GO:0071103)3.23186621
66positive regulation of mitotic sister chromatid separation (GO:1901970)3.23066243
67positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.23066243
68positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.23066243
69protein localization to chromosome (GO:0034502)3.22868254
70chromosome segregation (GO:0007059)3.21776728
71membrane disassembly (GO:0030397)3.21760654
72nuclear envelope disassembly (GO:0051081)3.21760654
73spindle checkpoint (GO:0031577)3.20431356
74ATP-dependent chromatin remodeling (GO:0043044)3.20160507
75regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.19703599
76double-strand break repair via nonhomologous end joining (GO:0006303)3.18771737
77non-recombinational repair (GO:0000726)3.18771737
78DNA strand elongation involved in DNA replication (GO:0006271)3.17238690
79protein prenylation (GO:0018342)3.14638494
80prenylation (GO:0097354)3.14638494
81DNA replication-dependent nucleosome organization (GO:0034723)3.14222199
82DNA replication-dependent nucleosome assembly (GO:0006335)3.14222199
83regulation of mitotic metaphase/anaphase transition (GO:0030071)3.13943900
84DNA synthesis involved in DNA repair (GO:0000731)3.13810828
85histone-serine phosphorylation (GO:0035404)3.13373970
86positive regulation of chromosome segregation (GO:0051984)3.13137550
87rRNA methylation (GO:0031167)3.12271174
88telomere maintenance via semi-conservative replication (GO:0032201)3.11176384
89translesion synthesis (GO:0019985)3.10936895
90acrosome reaction (GO:0007340)3.10858609
91pre-miRNA processing (GO:0031054)3.10824412
92regulation of centrosome cycle (GO:0046605)3.09422896
93histone H3-K9 methylation (GO:0051567)3.08681912
94regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.08440187
95spindle assembly checkpoint (GO:0071173)3.07384071
96regulation of sister chromatid cohesion (GO:0007063)3.07084870
97regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.06556622
98telomere maintenance via recombination (GO:0000722)3.05825058
99regulation of chromosome segregation (GO:0051983)3.04676398
100DNA packaging (GO:0006323)3.04035699
101DNA strand elongation (GO:0022616)3.03953246
102centriole assembly (GO:0098534)3.03312867
103replication fork processing (GO:0031297)3.03115514
104regulation of mitotic sister chromatid separation (GO:0010965)3.00398211
105regulation of mitotic sister chromatid segregation (GO:0033047)3.00398211
106regulation of sister chromatid segregation (GO:0033045)3.00398211
107mismatch repair (GO:0006298)2.98835062
108nucleus organization (GO:0006997)2.98403953
109regulation of centrosome duplication (GO:0010824)2.97693879
110negative regulation of chromosome segregation (GO:0051985)2.97634054
111negative regulation of mitotic sister chromatid segregation (GO:0033048)2.97463059
112negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.97463059
113negative regulation of sister chromatid segregation (GO:0033046)2.97463059
114negative regulation of mitotic sister chromatid separation (GO:2000816)2.97463059
115chromosome condensation (GO:0030261)2.97222091
116reciprocal meiotic recombination (GO:0007131)2.94906398
117reciprocal DNA recombination (GO:0035825)2.94906398
118resolution of meiotic recombination intermediates (GO:0000712)2.93636255
119interkinetic nuclear migration (GO:0022027)2.92870566
120microtubule nucleation (GO:0007020)2.92436153
121negative regulation of DNA recombination (GO:0045910)2.92408078
122mitotic G2 DNA damage checkpoint (GO:0007095)2.91965255
123meiotic cell cycle (GO:0051321)2.91257064
124mitotic spindle checkpoint (GO:0071174)2.90390734
125regulation of DNA-dependent DNA replication (GO:0090329)2.90374671
126protein localization to Golgi apparatus (GO:0034067)2.90331196
127mitotic spindle assembly checkpoint (GO:0007094)2.89738206
128peptidyl-lysine trimethylation (GO:0018023)2.89253953
129regulation of helicase activity (GO:0051095)2.88801331
130regulation of mitotic spindle checkpoint (GO:1903504)2.88580733
131regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.88580733
132mRNA splice site selection (GO:0006376)2.88538478
133negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.88387783
134monoubiquitinated protein deubiquitination (GO:0035520)2.88272258
135positive regulation of histone H3-K4 methylation (GO:0051571)2.86300454
136chromatin assembly (GO:0031497)2.83743543
137somatic hypermutation of immunoglobulin genes (GO:0016446)2.82706851

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.22423373
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.11605910
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.73803721
4SALL1_21062744_ChIP-ChIP_HESCs_Human3.15665386
5KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.14899049
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.70329012
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.56748196
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.55292684
9E2F1_21310950_ChIP-Seq_MCF-7_Human2.53643507
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.52724049
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.44774351
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.39549197
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.30285868
14MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.09375210
15YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.01968766
16E2F7_22180533_ChIP-Seq_HELA_Human11.7480666
17AR_21909140_ChIP-Seq_LNCAP_Human1.98632857
18MYC_19079543_ChIP-ChIP_MESCs_Mouse1.94416225
19TAF15_26573619_Chip-Seq_HEK293_Human1.88979245
20MYC_19030024_ChIP-ChIP_MESCs_Mouse1.88462383
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82062347
22FUS_26573619_Chip-Seq_HEK293_Human1.79467288
23PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.78941532
24RBPJ_22232070_ChIP-Seq_NCS_Mouse1.76887252
25IGF1R_20145208_ChIP-Seq_DFB_Human1.76651854
26CIITA_25753668_ChIP-Seq_RAJI_Human1.75888256
27ZNF274_21170338_ChIP-Seq_K562_Hela1.74642671
28EST1_17652178_ChIP-ChIP_JURKAT_Human1.69058198
29EWS_26573619_Chip-Seq_HEK293_Human1.64974569
30HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.63319820
31ER_23166858_ChIP-Seq_MCF-7_Human1.61771356
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.58154696
33P300_19829295_ChIP-Seq_ESCs_Human1.57556232
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.57026875
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.55963887
36VDR_22108803_ChIP-Seq_LS180_Human1.55734672
37ELK1_19687146_ChIP-ChIP_HELA_Human1.55318078
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.55068116
39VDR_23849224_ChIP-Seq_CD4+_Human1.52495682
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52025419
41GBX2_23144817_ChIP-Seq_PC3_Human1.48847864
42IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48558966
43CBP_20019798_ChIP-Seq_JUKART_Human1.48558966
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46251649
45FOXP3_21729870_ChIP-Seq_TREG_Human1.45102797
46KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.44171362
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.42009359
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38587711
49TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38587711
50STAT3_23295773_ChIP-Seq_U87_Human1.36729126
51ZFP57_27257070_Chip-Seq_ESCs_Mouse1.35540736
52XRN2_22483619_ChIP-Seq_HELA_Human1.34986119
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31449388
54MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.30062320
55SOX2_18555785_ChIP-Seq_MESCs_Mouse1.29655408
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29293113
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27625853
58ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25979033
59MYC_18358816_ChIP-ChIP_MESCs_Mouse1.25511900
60TTF2_22483619_ChIP-Seq_HELA_Human1.24476522
61EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.23645751
62SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.22811265
63HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.20463842
64TCF4_23295773_ChIP-Seq_U87_Human1.20263490
65HOXB4_20404135_ChIP-ChIP_EML_Mouse1.20198563
66TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.19192720
67SMAD4_21799915_ChIP-Seq_A2780_Human1.16950075
68FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16152381
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.15478567
70FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15378377
71NFYB_21822215_ChIP-Seq_K562_Human1.13463740
72ELF1_17652178_ChIP-ChIP_JURKAT_Human1.12558658
73ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.11878999
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11332846
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.10052148
76MYC_22102868_ChIP-Seq_BL_Human1.08478262
77AR_21572438_ChIP-Seq_LNCaP_Human1.07765889
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07456146
79POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.06583315
80TBL1_22424771_ChIP-Seq_293T_Human1.06272045
81CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.05252415
82NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04819786
83SOX2_16153702_ChIP-ChIP_HESCs_Human1.04304837
84GATA1_26923725_Chip-Seq_HPCs_Mouse1.03915011
85PKCTHETA_26484144_Chip-Seq_BREAST_Human1.03695107
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.02365504
87FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02050463
88SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01760204
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01545930
90AR_25329375_ChIP-Seq_VCAP_Human1.00964141
91KDM5A_27292631_Chip-Seq_BREAST_Human1.00872979
92E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99625850
93NANOG_18555785_Chip-Seq_ESCs_Mouse0.99422682
94ETS1_20019798_ChIP-Seq_JURKAT_Human0.99311320
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99181070
96TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98586995
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98532573
98GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.98476337
99CBX2_22325352_ChIP-Seq_293T-Rex_Human0.97726778
100FLI1_27457419_Chip-Seq_LIVER_Mouse0.97355259
101TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96904623
102KLF5_20875108_ChIP-Seq_MESCs_Mouse0.96708021
103DCP1A_22483619_ChIP-Seq_HELA_Human0.96073378
104E2F1_18555785_Chip-Seq_ESCs_Mouse0.95868779
105ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.95403951
106ETV1_20927104_ChIP-Seq_GIST48_Human0.95224478
107SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94766185
108PIAS1_25552417_ChIP-Seq_VCAP_Human0.94711918
109THAP11_20581084_ChIP-Seq_MESCs_Mouse0.94561629
110PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94445823
111TCF4_22108803_ChIP-Seq_LS180_Human0.92118415
112HNFA_21074721_ChIP-Seq_CACO-2_Human0.91880708
113MYC_18940864_ChIP-ChIP_HL60_Human0.91663195
114RBPJ_21746931_ChIP-Seq_IB4_Human0.91373593
115RUNX2_22187159_ChIP-Seq_PCA_Human0.91215142
116TP53_22573176_ChIP-Seq_HFKS_Human0.91126225
117POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90353540
118PHF8_20622853_ChIP-Seq_HELA_Human0.90098800
119NFYA_21822215_ChIP-Seq_K562_Human0.89550505
120SUZ12_27294783_Chip-Seq_NPCs_Mouse0.89504967
121NFE2_27457419_Chip-Seq_LIVER_Mouse0.89380041
122TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.89349968
123CREB1_15753290_ChIP-ChIP_HEK293T_Human0.88626314
124CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.88402783
125PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.87767833
126PCGF2_27294783_Chip-Seq_ESCs_Mouse0.86781641
127HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.86772843
128FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.84545629
129CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.84197182
130POU3F2_20337985_ChIP-ChIP_501MEL_Human0.83404932
131SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.81177021
132GABP_17652178_ChIP-ChIP_JURKAT_Human0.80008639
133EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.79473444
134SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.79185336
135SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.78556284
136ERG_20887958_ChIP-Seq_HPC-7_Mouse0.78138565
137SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.76266091
138GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75290922
139PCGF2_27294783_Chip-Seq_NPCs_Mouse0.74556559
140ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.74066208
141RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.74041804
142DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.72677235
143TP53_16413492_ChIP-PET_HCT116_Human0.71105153
144SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.70833138
145NANOG_21062744_ChIP-ChIP_HESCs_Human0.70510011
146CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.70011176
147POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.67414121
148GABP_19822575_ChIP-Seq_HepG2_Human0.67055867
149SCL_19346495_ChIP-Seq_HPC-7_Human0.66979929
150SOX9_26525672_Chip-Seq_HEART_Mouse0.66607451
151KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.66478509
152ZFX_18555785_ChIP-Seq_MESCs_Mouse0.65538000
153IRF1_19129219_ChIP-ChIP_H3396_Human0.65362939
154MYB_26560356_Chip-Seq_TH1_Human0.64175949

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.51789104
2MP0008057_abnormal_DNA_replication4.29740974
3MP0003111_abnormal_nucleus_morphology3.74440824
4MP0003693_abnormal_embryo_hatching3.53797433
5MP0003077_abnormal_cell_cycle3.29404005
6MP0008058_abnormal_DNA_repair3.21361403
7MP0008877_abnormal_DNA_methylation3.21120772
8MP0000569_abnormal_digit_pigmentation3.20497447
9MP0003787_abnormal_imprinting2.86957893
10MP0004957_abnormal_blastocyst_morpholog2.85993649
11MP0003121_genomic_imprinting2.67457701
12MP0003718_maternal_effect2.59200922
13MP0002396_abnormal_hematopoietic_system2.38747589
14MP0003123_paternal_imprinting2.22992992
15MP0008007_abnormal_cellular_replicative2.16544379
16MP0005174_abnormal_tail_pigmentation1.96970637
17MP0010307_abnormal_tumor_latency1.89620481
18MP0006292_abnormal_olfactory_placode1.84860848
19MP0008932_abnormal_embryonic_tissue1.83069067
20MP0000350_abnormal_cell_proliferation1.77716555
21MP0003786_premature_aging1.69757782
22MP0004808_abnormal_hematopoietic_stem1.61308936
23MP0001672_abnormal_embryogenesis/_devel1.57281625
24MP0005380_embryogenesis_phenotype1.57281625
25MP0003890_abnormal_embryonic-extraembry1.53864995
26MP0001730_embryonic_growth_arrest1.47879935
27MP0002102_abnormal_ear_morphology1.47365102
28MP0002084_abnormal_developmental_patter1.45352390
29MP0002210_abnormal_sex_determination1.43071375
30MP0001293_anophthalmia1.42893085
31MP0000566_synostosis1.40258072
32MP0010352_gastrointestinal_tract_polyps1.40010029
33MP0003984_embryonic_growth_retardation1.39881104
34MP0001929_abnormal_gametogenesis1.38920261
35MP0002160_abnormal_reproductive_system1.38108909
36MP0002085_abnormal_embryonic_tissue1.37359126
37MP0002088_abnormal_embryonic_growth/wei1.36529597
38MP0000015_abnormal_ear_pigmentation1.36052471
39MP0002234_abnormal_pharynx_morphology1.35011978
40MP0002095_abnormal_skin_pigmentation1.34754527
41MP0002938_white_spotting1.34568571
42MP0004197_abnormal_fetal_growth/weight/1.34436528
43MP0001697_abnormal_embryo_size1.30064359
44MP0000490_abnormal_crypts_of1.27920903
45MP0002086_abnormal_extraembryonic_tissu1.23997778
46MP0002928_abnormal_bile_duct1.23841492
47MP0005551_abnormal_eye_electrophysiolog1.20605798
48MP0003937_abnormal_limbs/digits/tail_de1.19002802
49MP0001145_abnormal_male_reproductive1.18488668
50MP0003763_abnormal_thymus_physiology1.17685085
51MP0005076_abnormal_cell_differentiation1.16843438
52MP0008995_early_reproductive_senescence1.16827806
53MP0000631_abnormal_neuroendocrine_gland1.16685505
54MP0000703_abnormal_thymus_morphology1.16119129
55MP0000383_abnormal_hair_follicle1.12583245
56MP0000313_abnormal_cell_death1.12312189
57MP0009703_decreased_birth_body1.11327327
58MP0003567_abnormal_fetal_cardiomyocyte1.10157531
59MP0002080_prenatal_lethality1.06046063
60MP0003698_abnormal_male_reproductive1.04862449
61MP0003136_yellow_coat_color1.03267631
62MP0000432_abnormal_head_morphology1.02166576
63MP0000653_abnormal_sex_gland1.02135031
64MP0001485_abnormal_pinna_reflex0.99528929
65MP0005409_darkened_coat_color0.99459392
66MP0003935_abnormal_craniofacial_develop0.98076624
67MP0001286_abnormal_eye_development0.97617636
68MP0006072_abnormal_retinal_apoptosis0.97609463
69MP0005253_abnormal_eye_physiology0.96048476
70MP0002009_preneoplasia0.94141165
71MP0002019_abnormal_tumor_incidence0.92426116
72MP0005395_other_phenotype0.92281028
73MP0005646_abnormal_pituitary_gland0.91616245
74MP0010030_abnormal_orbit_morphology0.91395064
75MP0005645_abnormal_hypothalamus_physiol0.90965209
76MP0005171_absent_coat_pigmentation0.90901976
77MP0003943_abnormal_hepatobiliary_system0.90730539
78MP0002398_abnormal_bone_marrow0.90028089
79MP0005391_vision/eye_phenotype0.89733890
80MP0010678_abnormal_skin_adnexa0.89681602
81MP0005397_hematopoietic_system_phenotyp0.89080815
82MP0001545_abnormal_hematopoietic_system0.89080815
83MP0002075_abnormal_coat/hair_pigmentati0.88501771
84MP0005187_abnormal_penis_morphology0.87653549
85MP0005083_abnormal_biliary_tract0.87513352
86MP0003122_maternal_imprinting0.84654821
87MP0003755_abnormal_palate_morphology0.84335914
88MP0003699_abnormal_female_reproductive0.82491280
89MP0003861_abnormal_nervous_system0.82480679
90MP0009278_abnormal_bone_marrow0.81833135
91MP0000372_irregular_coat_pigmentation0.81761401
92MP0001188_hyperpigmentation0.81521175
93MP0009672_abnormal_birth_weight0.80459178
94MP0002006_tumorigenesis0.79773302
95MP0005075_abnormal_melanosome_morpholog0.78938025
96MP0000428_abnormal_craniofacial_morphol0.77803721
97MP0002177_abnormal_outer_ear0.77140724
98MP0002092_abnormal_eye_morphology0.77138635
99MP0003646_muscle_fatigue0.76422553
100MP0003938_abnormal_ear_development0.76188699
101MP0009697_abnormal_copulation0.75990470
102MP0005389_reproductive_system_phenotype0.75716264
103MP0003315_abnormal_perineum_morphology0.75281091
104MP0003115_abnormal_respiratory_system0.74863883
105MP0008961_abnormal_basal_metabolism0.74548286
106MP0005379_endocrine/exocrine_gland_phen0.74447783
107MP0001186_pigmentation_phenotype0.74395423
108MP0000537_abnormal_urethra_morphology0.73781358
109MP0000778_abnormal_nervous_system0.72023594
110MP0005377_hearing/vestibular/ear_phenot0.71998319
111MP0003878_abnormal_ear_physiology0.71998319
112MP0004742_abnormal_vestibular_system0.71331989
113MP0005410_abnormal_fertilization0.70855566
114MP0002166_altered_tumor_susceptibility0.70659416
115MP0002722_abnormal_immune_system0.70263088
116MP0001119_abnormal_female_reproductive0.70067119
117MP0002697_abnormal_eye_size0.68525718
118MP0002116_abnormal_craniofacial_bone0.66756949
119MP0001529_abnormal_vocalization0.66457525
120MP0002114_abnormal_axial_skeleton0.66120028
121MP0003385_abnormal_body_wall0.66099083
122MP0008770_decreased_survivor_rate0.65177486
123MP0005367_renal/urinary_system_phenotyp0.64763635
124MP0000516_abnormal_urinary_system0.64763635
125MP0003950_abnormal_plasma_membrane0.64319966
126MP0000647_abnormal_sebaceous_gland0.63402080
127MP0000689_abnormal_spleen_morphology0.63371467
128MP0001346_abnormal_lacrimal_gland0.63134260
129MP0002109_abnormal_limb_morphology0.62898491
130MP0000427_abnormal_hair_cycle0.62208566
131MP0006276_abnormal_autonomic_nervous0.61928955
132MP0003119_abnormal_digestive_system0.61747817
133MP0004381_abnormal_hair_follicle0.61485238
134MP0002925_abnormal_cardiovascular_devel0.61097936
135MP0002161_abnormal_fertility/fecundity0.60767029
136MP0002638_abnormal_pupillary_reflex0.60458447
137MP0002233_abnormal_nose_morphology0.60315078
138MP0005310_abnormal_salivary_gland0.60070936

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.01543179
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.71238867
3Volvulus (HP:0002580)4.34544460
4Abnormality of chromosome stability (HP:0003220)3.47023251
5Chronic hepatic failure (HP:0100626)3.24842504
6Ectopic kidney (HP:0000086)3.18128885
7Medulloblastoma (HP:0002885)3.16364192
8Pancreatic cysts (HP:0001737)3.12871952
9Abnormality of the fingertips (HP:0001211)3.01957268
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.98845831
11Short 4th metacarpal (HP:0010044)2.98845831
12Aplasia/Hypoplasia of the uvula (HP:0010293)2.86702548
13Meckel diverticulum (HP:0002245)2.80585384
14Duplicated collecting system (HP:0000081)2.79599104
15Reticulocytopenia (HP:0001896)2.78490384
16Abnormality of the preputium (HP:0100587)2.78300077
17Pancreatic fibrosis (HP:0100732)2.75663382
18Abnormality of the ileum (HP:0001549)2.67636257
19Nephroblastoma (Wilms tumor) (HP:0002667)2.59500165
20Neoplasm of the oral cavity (HP:0100649)2.59160657
21Abnormality of the labia minora (HP:0012880)2.58703278
22Increased nuchal translucency (HP:0010880)2.57441213
23Small intestinal stenosis (HP:0012848)2.52777228
24Duodenal stenosis (HP:0100867)2.52777228
25Impulsivity (HP:0100710)2.50345190
26Abnormality of the renal collecting system (HP:0004742)2.49047985
27Abnormality of DNA repair (HP:0003254)2.48501513
28Abnormal number of incisors (HP:0011064)2.42002222
29Long eyelashes (HP:0000527)2.41795144
30Colon cancer (HP:0003003)2.41508843
31Myelodysplasia (HP:0002863)2.39287854
32Embryonal renal neoplasm (HP:0011794)2.38759351
33Selective tooth agenesis (HP:0001592)2.36400945
34Supernumerary ribs (HP:0005815)2.35861755
35Supernumerary spleens (HP:0009799)2.35413269
36Prominent nose (HP:0000448)2.33802344
37Abnormality of the renal cortex (HP:0011035)2.31937444
38Birth length less than 3rd percentile (HP:0003561)2.31741726
39Hypoplasia of the pons (HP:0012110)2.31364147
40Sloping forehead (HP:0000340)2.29983186
41Supernumerary bones of the axial skeleton (HP:0009144)2.28214297
42Ependymoma (HP:0002888)2.27542183
43Molar tooth sign on MRI (HP:0002419)2.27126053
44Abnormality of midbrain morphology (HP:0002418)2.27126053
45Abnormality of the carotid arteries (HP:0005344)2.25726033
46Abnormality of the pons (HP:0007361)2.24637345
47Abnormality of the renal medulla (HP:0100957)2.23254039
48Arteriovenous malformation (HP:0100026)2.18384344
49Proximal placement of thumb (HP:0009623)2.17407565
50Clubbing of toes (HP:0100760)2.15173616
51Abnormality of the incisor (HP:0000676)2.14018165
52Astigmatism (HP:0000483)2.14007660
53Cerebellar dysplasia (HP:0007033)2.13976454
54True hermaphroditism (HP:0010459)2.12938971
55Deviation of the thumb (HP:0009603)2.12791367
56Aplasia/Hypoplasia of the sacrum (HP:0008517)2.12508148
57Patellar aplasia (HP:0006443)2.09156651
58Acute myeloid leukemia (HP:0004808)2.07130678
5911 pairs of ribs (HP:0000878)2.06806034
60Attenuation of retinal blood vessels (HP:0007843)2.05017001
61Absent frontal sinuses (HP:0002688)2.02677816
62Abnormality of the duodenum (HP:0002246)2.00598820
63Gaze-evoked nystagmus (HP:0000640)1.98308829
64Oligohydramnios (HP:0001562)1.98245186
65Aqueductal stenosis (HP:0002410)1.98172573
66Truncal obesity (HP:0001956)1.98155345
67Poor coordination (HP:0002370)1.97565843
68Deep philtrum (HP:0002002)1.96229054
69Breast hypoplasia (HP:0003187)1.95200168
70Abnormal lung lobation (HP:0002101)1.95084327
71Short thumb (HP:0009778)1.94989568
72Heterotopia (HP:0002282)1.93743191
73Absent radius (HP:0003974)1.93276414
74Glioma (HP:0009733)1.92683074
75Fair hair (HP:0002286)1.92492664
76Abnormality of the astrocytes (HP:0100707)1.91649383
77Astrocytoma (HP:0009592)1.91649383
78Trigonocephaly (HP:0000243)1.91029109
79Abnormality of the columella (HP:0009929)1.89066198
80Tubular atrophy (HP:0000092)1.88750986
81Agnosia (HP:0010524)1.87245104
82Aplasia/Hypoplasia of the tongue (HP:0010295)1.87039614
83Aplasia/Hypoplasia of the patella (HP:0006498)1.86250249
84Facial hemangioma (HP:0000329)1.85404770
85Cystic hygroma (HP:0000476)1.83751950
86Tubulointerstitial nephritis (HP:0001970)1.83365026
87Renal cortical cysts (HP:0000803)1.83330214
88Abnormality of the parietal bone (HP:0002696)1.82607125
89Urethral obstruction (HP:0000796)1.82467636
90Aplasia involving forearm bones (HP:0009822)1.82460150
91Absent forearm bone (HP:0003953)1.82460150
92Small hand (HP:0200055)1.81690413
93Esophageal atresia (HP:0002032)1.81474308
94Aplasia/Hypoplasia of the sternum (HP:0006714)1.81400928
95Midline defect of the nose (HP:0004122)1.80158092
96High pitched voice (HP:0001620)1.79414742
97Cafe-au-lait spot (HP:0000957)1.78875305
98Aplasia/Hypoplasia of the earlobes (HP:0009906)1.78381998
99Microtia (HP:0008551)1.78288360
100Anophthalmia (HP:0000528)1.77986163
101Neoplasm of striated muscle (HP:0009728)1.77644664
102Capillary hemangiomas (HP:0005306)1.77374963
103Pancreatic islet-cell hyperplasia (HP:0004510)1.77216401
104Bony spicule pigmentary retinopathy (HP:0007737)1.77061423
105Tubulointerstitial abnormality (HP:0001969)1.76044354
106Gastrointestinal atresia (HP:0002589)1.75430831
107Rhabdomyosarcoma (HP:0002859)1.73893970
108Abnormality of chromosome segregation (HP:0002916)1.73765497
109Abnormality of the distal phalanx of the thumb (HP:0009617)1.72856888
110Absent/shortened dynein arms (HP:0200106)1.72851654
111Dynein arm defect of respiratory motile cilia (HP:0012255)1.72851654
112Abnormality of the 4th metacarpal (HP:0010012)1.71599798
113Oligodactyly (hands) (HP:0001180)1.70732490
114Cystic liver disease (HP:0006706)1.70573729
115Abnormality of the ischium (HP:0003174)1.69599502
116Papillary thyroid carcinoma (HP:0002895)1.69431769
117Abnormality of the nasal septum (HP:0000419)1.68849299
118Sclerocornea (HP:0000647)1.68672918
119Severe visual impairment (HP:0001141)1.68552562
120Homocystinuria (HP:0002156)1.68528263
121Abnormality of homocysteine metabolism (HP:0010919)1.68528263
122Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.67617092
123Abnormality of alanine metabolism (HP:0010916)1.67617092
124Hyperalaninemia (HP:0003348)1.67617092
125Bone marrow hypocellularity (HP:0005528)1.64999087
126Highly arched eyebrow (HP:0002553)1.64002440
127Atresia of the external auditory canal (HP:0000413)1.63941895
128Low anterior hairline (HP:0000294)1.63373935
129Duplication of thumb phalanx (HP:0009942)1.63080892
130Basal cell carcinoma (HP:0002671)1.62321185
131Triphalangeal thumb (HP:0001199)1.61294594
132Obsessive-compulsive behavior (HP:0000722)1.61263536
133Acute lymphatic leukemia (HP:0006721)1.60292058
134Anal stenosis (HP:0002025)1.58947171
135Limited elbow extension (HP:0001377)1.57620721
136Absent thumb (HP:0009777)1.57325621
137Oligodactyly (HP:0012165)1.54774323
138Large earlobe (HP:0009748)1.54228920
139Hypoplastic iliac wings (HP:0002866)1.53169268
140Premature graying of hair (HP:0002216)1.52355371
141Sandal gap (HP:0001852)1.52234313
142Broad thumb (HP:0011304)1.51592203
143Embryonal neoplasm (HP:0002898)1.51158249
144Nephronophthisis (HP:0000090)1.51124937
145Abnormality of the phalanges of the hallux (HP:0010057)1.50347058

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.40175982
2CDK124.00774260
3FRK3.58851256
4NEK23.34595448
5SRPK13.01256946
6WEE12.90020988
7BRD42.82562869
8TTK2.76206382
9BMPR1B2.65184622
10EIF2AK12.52144173
11ATR2.47646113
12TLK12.21311825
13MKNK12.10026402
14PLK42.06659342
15MKNK21.93339554
16CHEK21.90681905
17ZAK1.85197495
18BUB11.84733461
19PLK11.79274905
20CHEK11.77880595
21AURKB1.72535935
22ATM1.69240630
23PLK31.68057364
24BRSK21.59393637
25AKT31.53705954
26PNCK1.47147208
27VRK11.44492242
28CDK71.44472772
29CDK41.41986987
30WNK31.32618503
31TAF11.31176356
32STK41.31065378
33INSRR1.28824833
34STK38L1.27668267
35CDK61.24120890
36CASK1.20949535
37PBK1.19367289
38PASK1.17771729
39STK31.16376593
40YES11.14306656
41EEF2K1.13692562
42RPS6KB21.12555233
43CDK21.10294015
44CAMK1D1.09395079
45LATS11.08156742
46EIF2AK21.07517649
47CLK11.06541856
48MAP4K21.05829862
49TSSK61.04433271
50CDK11.04032303
51DYRK31.04030050
52SCYL21.02923770
53VRK21.01324066
54NUAK10.98616111
55MELK0.97431029
56STK100.95776017
57CDK90.95305674
58CAMK1G0.92331700
59STK390.90387825
60CCNB10.88838108
61PIM10.88773861
62TNIK0.87795580
63BRSK10.86933737
64WNK40.86198286
65MAP3K40.85499189
66TXK0.79437975
67PRKDC0.78949736
68TEC0.78736097
69CSNK1D0.77967320
70FGFR20.77436678
71RPS6KA50.77388972
72ACVR1B0.77300010
73NEK60.73274752
74MAPK140.71394832
75NEK10.70141824
76MST40.66372216
77MAP3K80.65746198
78MTOR0.65508253
79AURKA0.63750952
80ERBB30.62425475
81EIF2AK30.60594122
82RPS6KA40.59701264
83PDK20.59084045
84ALK0.57870644
85GSK3B0.57821194
86NLK0.57327672
87TAOK30.57111266
88MAPK130.56686024
89CSNK1A1L0.56448529
90CDK80.56241342
91MAP3K100.55678098
92OXSR10.55028771
93CSNK2A20.53924156
94BLK0.53025347
95PKN20.51055414
96FGFR10.51004441
97CSNK1E0.50691610
98CHUK0.50092093
99PLK20.49157793
100CDK30.48465838
101MAP3K60.47799033
102AKT10.47577211
103RPS6KB10.45635859
104SIK20.44236224
105MAPK10.43096971
106MAPK100.42505601
107PIK3CG0.41351867
108MAP4K10.40996444
109SGK10.40041826
110PRKD30.37593072
111ICK0.36119503
112MST1R0.35866479
113CSNK2A10.35835622
114WNK10.35773973
115MAP3K140.34819164
116MAPK80.34593319
117AKT20.33195380
118NEK90.32080425
119MARK30.31079661
120CAMK40.30924380
121CSF1R0.29870931
122MAP2K70.29838685
123PRKAA20.29657297
124NME10.29603282
125SGK20.29405949
126TGFBR10.29239905
127BTK0.29189269
128FLT30.27634577
129PRKAA10.27424162
130STK160.27381566
131PRKACB0.24791506
132STK380.24235989

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.62716362
2Mismatch repair_Homo sapiens_hsa034303.53952364
3Fanconi anemia pathway_Homo sapiens_hsa034603.21384268
4Homologous recombination_Homo sapiens_hsa034403.13547588
5Cell cycle_Homo sapiens_hsa041102.92588800
6Non-homologous end-joining_Homo sapiens_hsa034502.85893435
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.78354422
8Spliceosome_Homo sapiens_hsa030402.72677904
9RNA transport_Homo sapiens_hsa030132.46274343
10Base excision repair_Homo sapiens_hsa034102.42207559
11Nucleotide excision repair_Homo sapiens_hsa034202.30275730
12mRNA surveillance pathway_Homo sapiens_hsa030152.27361030
13Systemic lupus erythematosus_Homo sapiens_hsa053222.16768955
14RNA degradation_Homo sapiens_hsa030182.03273048
15Basal transcription factors_Homo sapiens_hsa030221.92918790
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.84434586
17One carbon pool by folate_Homo sapiens_hsa006701.81663904
18RNA polymerase_Homo sapiens_hsa030201.67159133
19p53 signaling pathway_Homo sapiens_hsa041151.65660432
20Fatty acid biosynthesis_Homo sapiens_hsa000611.64602346
21Ribosome_Homo sapiens_hsa030101.48779151
22Olfactory transduction_Homo sapiens_hsa047401.39521633
23Selenocompound metabolism_Homo sapiens_hsa004501.38939632
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.37846275
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.35884839
26Herpes simplex infection_Homo sapiens_hsa051681.29883387
27Viral carcinogenesis_Homo sapiens_hsa052031.28455783
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.27581710
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27243082
30Transcriptional misregulation in cancer_Homo sapiens_hsa052021.26994162
31Pyrimidine metabolism_Homo sapiens_hsa002401.26015095
32Oocyte meiosis_Homo sapiens_hsa041141.24838093
33MicroRNAs in cancer_Homo sapiens_hsa052061.22987808
34Alcoholism_Homo sapiens_hsa050341.21008124
35Lysine degradation_Homo sapiens_hsa003101.13244499
36Primary immunodeficiency_Homo sapiens_hsa053401.08507997
37Epstein-Barr virus infection_Homo sapiens_hsa051691.07686207
38Small cell lung cancer_Homo sapiens_hsa052221.05170257
39Taste transduction_Homo sapiens_hsa047421.02183034
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99942224
41NOD-like receptor signaling pathway_Homo sapiens_hsa046210.97982361
42HTLV-I infection_Homo sapiens_hsa051660.97447843
43Propanoate metabolism_Homo sapiens_hsa006400.96254943
44Basal cell carcinoma_Homo sapiens_hsa052170.95581599
45Butanoate metabolism_Homo sapiens_hsa006500.88316259
46NF-kappa B signaling pathway_Homo sapiens_hsa040640.88179777
47Nitrogen metabolism_Homo sapiens_hsa009100.87473260
48Colorectal cancer_Homo sapiens_hsa052100.87215517
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85502437
50Cysteine and methionine metabolism_Homo sapiens_hsa002700.83261329
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83065131
52Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82556638
53Nicotine addiction_Homo sapiens_hsa050330.82077318
54Prostate cancer_Homo sapiens_hsa052150.81924934
55Chronic myeloid leukemia_Homo sapiens_hsa052200.78048110
56Inositol phosphate metabolism_Homo sapiens_hsa005620.77967913
57Antigen processing and presentation_Homo sapiens_hsa046120.76677562
58Purine metabolism_Homo sapiens_hsa002300.76413662
59Hepatitis B_Homo sapiens_hsa051610.76342441
60Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.75314903
61Circadian rhythm_Homo sapiens_hsa047100.72911008
62Notch signaling pathway_Homo sapiens_hsa043300.71488422
63Hematopoietic cell lineage_Homo sapiens_hsa046400.70998728
64Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70453552
65Measles_Homo sapiens_hsa051620.68131707
66T cell receptor signaling pathway_Homo sapiens_hsa046600.67716734
67TGF-beta signaling pathway_Homo sapiens_hsa043500.66663870
68B cell receptor signaling pathway_Homo sapiens_hsa046620.66302994
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.65872873
70Wnt signaling pathway_Homo sapiens_hsa043100.64562253
71Adherens junction_Homo sapiens_hsa045200.64535496
72Pathways in cancer_Homo sapiens_hsa052000.63353668
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61115444
74Vitamin digestion and absorption_Homo sapiens_hsa049770.59853098
75Viral myocarditis_Homo sapiens_hsa054160.57355620
76Hedgehog signaling pathway_Homo sapiens_hsa043400.57085199
77Hippo signaling pathway_Homo sapiens_hsa043900.55094641
78Huntingtons disease_Homo sapiens_hsa050160.54147935
79Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.53502437
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52926229
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52331863
82ABC transporters_Homo sapiens_hsa020100.51597920
83Autoimmune thyroid disease_Homo sapiens_hsa053200.51576834
84FoxO signaling pathway_Homo sapiens_hsa040680.51520241
85Pancreatic cancer_Homo sapiens_hsa052120.51149770
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.50027168
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49785937
88Influenza A_Homo sapiens_hsa051640.49688628
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49238358
90Protein export_Homo sapiens_hsa030600.49157048
91Non-small cell lung cancer_Homo sapiens_hsa052230.47390825
92Apoptosis_Homo sapiens_hsa042100.46409010
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46312310
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46008659
95mTOR signaling pathway_Homo sapiens_hsa041500.45709879
96Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45467630
97Dorso-ventral axis formation_Homo sapiens_hsa043200.43914659
98Renin-angiotensin system_Homo sapiens_hsa046140.43855615
99Folate biosynthesis_Homo sapiens_hsa007900.42956241
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.41190996
101Proteasome_Homo sapiens_hsa030500.41079733
102Melanoma_Homo sapiens_hsa052180.39800857
103Allograft rejection_Homo sapiens_hsa053300.38418240
104Endometrial cancer_Homo sapiens_hsa052130.36191633
105Acute myeloid leukemia_Homo sapiens_hsa052210.36185117
106Morphine addiction_Homo sapiens_hsa050320.34910204
107Shigellosis_Homo sapiens_hsa051310.34838780
108Pyruvate metabolism_Homo sapiens_hsa006200.34683440
109TNF signaling pathway_Homo sapiens_hsa046680.33806621
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.33777782
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32695608
112PI3K-Akt signaling pathway_Homo sapiens_hsa041510.32613909
113Toxoplasmosis_Homo sapiens_hsa051450.32093138
114Thyroid cancer_Homo sapiens_hsa052160.31353566
115Glioma_Homo sapiens_hsa052140.31221880
116Asthma_Homo sapiens_hsa053100.30698609
117Ether lipid metabolism_Homo sapiens_hsa005650.30149875
118Jak-STAT signaling pathway_Homo sapiens_hsa046300.30093294
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.29870786
120MAPK signaling pathway_Homo sapiens_hsa040100.28762373
121Phototransduction_Homo sapiens_hsa047440.28595970
122Leukocyte transendothelial migration_Homo sapiens_hsa046700.28438682
123Proteoglycans in cancer_Homo sapiens_hsa052050.28021625
124ErbB signaling pathway_Homo sapiens_hsa040120.27739164
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27158103
126Legionellosis_Homo sapiens_hsa051340.27097394
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25773071
128Metabolic pathways_Homo sapiens_hsa011000.25465063
129Sulfur relay system_Homo sapiens_hsa041220.24146210
130Chemokine signaling pathway_Homo sapiens_hsa040620.24127006
131Type II diabetes mellitus_Homo sapiens_hsa049300.23975041
132Osteoclast differentiation_Homo sapiens_hsa043800.23590024
133Graft-versus-host disease_Homo sapiens_hsa053320.23095886
134Serotonergic synapse_Homo sapiens_hsa047260.22750972
135Glycerophospholipid metabolism_Homo sapiens_hsa005640.21284760
136Long-term depression_Homo sapiens_hsa047300.19557038
137cAMP signaling pathway_Homo sapiens_hsa040240.19496539
138Steroid hormone biosynthesis_Homo sapiens_hsa001400.17079911
139Glycerolipid metabolism_Homo sapiens_hsa005610.16692025
140Calcium signaling pathway_Homo sapiens_hsa040200.16666140
141N-Glycan biosynthesis_Homo sapiens_hsa005100.15625922
142Glutamatergic synapse_Homo sapiens_hsa047240.15484205
143Regulation of autophagy_Homo sapiens_hsa041400.13779067
144Cholinergic synapse_Homo sapiens_hsa047250.13514117
145Longevity regulating pathway - mammal_Homo sapiens_hsa042110.13119316
146Peroxisome_Homo sapiens_hsa041460.11900095
147Linoleic acid metabolism_Homo sapiens_hsa005910.11633918

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