CEP57L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1telomere maintenance via semi-conservative replication (GO:0032201)4.77829084
2DNA strand elongation involved in DNA replication (GO:0006271)4.41909334
3telomere maintenance via recombination (GO:0000722)4.36864511
4kinetochore organization (GO:0051383)4.34114215
5nucleotide-excision repair, DNA gap filling (GO:0006297)4.27319466
6DNA strand elongation (GO:0022616)4.27252889
7kinetochore assembly (GO:0051382)4.26093069
8microtubule depolymerization (GO:0007019)4.18663493
9CENP-A containing nucleosome assembly (GO:0034080)4.15385208
10ribosomal small subunit biogenesis (GO:0042274)4.02714287
11mitotic recombination (GO:0006312)4.00422382
12DNA replication initiation (GO:0006270)3.99736571
13chromatin remodeling at centromere (GO:0031055)3.89425007
14ribosomal small subunit assembly (GO:0000028)3.85379615
15telomere maintenance via telomere lengthening (GO:0010833)3.83854722
16proteasome assembly (GO:0043248)3.68655264
17transcription elongation from RNA polymerase I promoter (GO:0006362)3.65162948
18rRNA modification (GO:0000154)3.64852799
19rRNA methylation (GO:0031167)3.56358417
20sister chromatid segregation (GO:0000819)3.50015182
21resolution of meiotic recombination intermediates (GO:0000712)3.46725062
22centriole replication (GO:0007099)3.45931710
23termination of RNA polymerase I transcription (GO:0006363)3.45811823
24transcription-coupled nucleotide-excision repair (GO:0006283)3.42514544
257-methylguanosine RNA capping (GO:0009452)3.41566801
26RNA capping (GO:0036260)3.41566801
27transcription elongation from RNA polymerase III promoter (GO:0006385)3.37284298
28termination of RNA polymerase III transcription (GO:0006386)3.37284298
29DNA replication checkpoint (GO:0000076)3.35554725
30DNA replication-independent nucleosome assembly (GO:0006336)3.33554665
31DNA replication-independent nucleosome organization (GO:0034724)3.33554665
32maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.32442421
33replication fork processing (GO:0031297)3.32234402
34exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.31296156
35histone exchange (GO:0043486)3.30257120
36regulation of nuclear cell cycle DNA replication (GO:0033262)3.29524811
37attachment of spindle microtubules to kinetochore (GO:0008608)3.28432121
38regulation of centriole replication (GO:0046599)3.28411144
397-methylguanosine mRNA capping (GO:0006370)3.28136873
40centriole assembly (GO:0098534)3.27931877
41negative regulation of DNA-dependent DNA replication (GO:2000104)3.26577520
42response to pheromone (GO:0019236)3.25290976
43deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.25060547
44establishment of integrated proviral latency (GO:0075713)3.21779127
45recombinational repair (GO:0000725)3.20010801
46DNA damage response, detection of DNA damage (GO:0042769)3.19583893
47regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.18515607
48regulation of mitotic spindle checkpoint (GO:1903504)3.18515607
49nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.18177630
50double-strand break repair via homologous recombination (GO:0000724)3.15732715
51DNA ligation (GO:0006266)3.15717890
52RNA methylation (GO:0001510)3.13945330
53transcription from RNA polymerase I promoter (GO:0006360)3.13695903
54microtubule polymerization or depolymerization (GO:0031109)3.08331745
55telomere maintenance (GO:0000723)3.07557941
56telomere organization (GO:0032200)3.07343704
57mismatch repair (GO:0006298)3.04460872
58DNA deamination (GO:0045006)3.03513135
59regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.03177810
60mitotic metaphase plate congression (GO:0007080)2.99784089
61DNA-dependent DNA replication (GO:0006261)2.98650119
62positive regulation of DNA-dependent DNA replication (GO:2000105)2.97342559
63regulation of centrosome cycle (GO:0046605)2.96356282
64nonmotile primary cilium assembly (GO:0035058)2.95528009
65organelle disassembly (GO:1903008)2.95227411
66regulation of double-strand break repair via homologous recombination (GO:0010569)2.94985511
67protein localization to kinetochore (GO:0034501)2.94297194
68protein K6-linked ubiquitination (GO:0085020)2.94263524
69lymphoid progenitor cell differentiation (GO:0002320)2.93782132
70DNA strand renaturation (GO:0000733)2.93501615
71maturation of SSU-rRNA (GO:0030490)2.92780920
72intraciliary transport (GO:0042073)2.92534473
73transcription initiation from RNA polymerase I promoter (GO:0006361)2.92515770
74meiotic chromosome segregation (GO:0045132)2.91874077
75metaphase plate congression (GO:0051310)2.90886880
76protein neddylation (GO:0045116)2.90434028
77negative regulation of telomere maintenance (GO:0032205)2.89942785
78mitotic spindle checkpoint (GO:0071174)2.89650158
79L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.88372810
80DNA unwinding involved in DNA replication (GO:0006268)2.86943378
81RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.86479581
82tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.86479581
83centrosome organization (GO:0051297)2.82133679
84pseudouridine synthesis (GO:0001522)2.81731734
85DNA synthesis involved in DNA repair (GO:0000731)2.81351712
86rRNA processing (GO:0006364)2.81128320
87negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.81086213
88negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.81086213
89negative regulation of mitotic sister chromatid segregation (GO:0033048)2.81086213
90negative regulation of mitotic sister chromatid separation (GO:2000816)2.81086213
91negative regulation of sister chromatid segregation (GO:0033046)2.81086213
92postreplication repair (GO:0006301)2.81028616
93neural tube formation (GO:0001841)2.80692719
94DNA double-strand break processing (GO:0000729)2.80326114
95viral mRNA export from host cell nucleus (GO:0046784)2.79964131
96mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.79693160
97mitochondrial respiratory chain complex I assembly (GO:0032981)2.79693160
98NADH dehydrogenase complex assembly (GO:0010257)2.79693160
99regulation of DNA endoreduplication (GO:0032875)2.79330763
100spindle assembly checkpoint (GO:0071173)2.79230956
101deoxyribonucleotide biosynthetic process (GO:0009263)2.78786863
102mitotic spindle assembly checkpoint (GO:0007094)2.78745009
103cullin deneddylation (GO:0010388)2.78368544
104chaperone-mediated protein transport (GO:0072321)2.78051251
105protein K11-linked ubiquitination (GO:0070979)2.77994633
106behavioral response to nicotine (GO:0035095)2.77423448
107negative regulation of chromosome segregation (GO:0051985)2.77200542
108RNA-dependent DNA replication (GO:0006278)2.76943489
109mannosylation (GO:0097502)2.75676162
110negative regulation of DNA recombination (GO:0045910)2.75320870
111nucleotide-excision repair (GO:0006289)2.74642131
112ribonucleoprotein complex biogenesis (GO:0022613)2.74573551
113reciprocal DNA recombination (GO:0035825)2.73887821
114reciprocal meiotic recombination (GO:0007131)2.73887821
115viral transcription (GO:0019083)2.73738929
116protein-cofactor linkage (GO:0018065)2.73552875
117mitotic sister chromatid segregation (GO:0000070)2.73487691
118protein complex biogenesis (GO:0070271)2.73283631
119regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.73216029
120regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.71787551
121regulation of mitotic metaphase/anaphase transition (GO:0030071)2.71787551
122regulation of cilium movement (GO:0003352)2.71736219
123DNA replication-dependent nucleosome organization (GO:0034723)2.71714360
124DNA replication-dependent nucleosome assembly (GO:0006335)2.71714360
125mitochondrial respiratory chain complex assembly (GO:0033108)2.71129795
126regulation of centrosome duplication (GO:0010824)2.70649082
127rRNA metabolic process (GO:0016072)2.70078587
128tRNA methylation (GO:0030488)2.69016597
129maturation of 5.8S rRNA (GO:0000460)2.69006919
130peptidyl-histidine modification (GO:0018202)2.68738405
131somatic hypermutation of immunoglobulin genes (GO:0016446)2.68524370
132somatic diversification of immune receptors via somatic mutation (GO:0002566)2.68524370
133DNA catabolic process, exonucleolytic (GO:0000738)2.67890990
134regulation of sister chromatid segregation (GO:0033045)2.67230451
135regulation of mitotic sister chromatid separation (GO:0010965)2.67230451
136regulation of mitotic sister chromatid segregation (GO:0033047)2.67230451
137positive regulation of histone H3-K4 methylation (GO:0051571)2.66586631
138microtubule organizing center organization (GO:0031023)2.66470482
139mitotic G2/M transition checkpoint (GO:0044818)2.66396930
140DNA replication (GO:0006260)2.65764373
141protein localization to chromosome, centromeric region (GO:0071459)2.64076192
142DNA topological change (GO:0006265)2.63627441
143regulation of spindle checkpoint (GO:0090231)2.62303333
144establishment of chromosome localization (GO:0051303)2.62093712
145translational termination (GO:0006415)2.61977356
146spermatid nucleus differentiation (GO:0007289)2.61644251
147platelet dense granule organization (GO:0060155)2.61479158
148ribosomal large subunit biogenesis (GO:0042273)2.60967293
149spliceosomal complex assembly (GO:0000245)2.60914919
150histone H2A acetylation (GO:0043968)2.60824402
151translesion synthesis (GO:0019985)2.60249645
152respiratory chain complex IV assembly (GO:0008535)2.59712641
153spliceosomal snRNP assembly (GO:0000387)2.59551576
154RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.59398300
155synapsis (GO:0007129)2.58762153
156histone mRNA metabolic process (GO:0008334)2.57980834
157pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.54192014
158spindle checkpoint (GO:0031577)2.52365492
159protein localization to chromosome (GO:0034502)2.51864537

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.00622881
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.76485619
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.60539778
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.35016463
5ZNF274_21170338_ChIP-Seq_K562_Hela3.12874113
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.12754748
7MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.99720707
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.91421222
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.90733364
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.83487184
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.79905306
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.77425533
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.68569270
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.60767419
15VDR_22108803_ChIP-Seq_LS180_Human2.55712828
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.55097069
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.49539189
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.48295871
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.48114758
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.27036209
21IGF1R_20145208_ChIP-Seq_DFB_Human2.25929113
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.24306236
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.21366325
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.02305072
25MYC_19030024_ChIP-ChIP_MESCs_Mouse1.98206743
26ETS1_20019798_ChIP-Seq_JURKAT_Human1.93106580
27BP1_19119308_ChIP-ChIP_Hs578T_Human1.91012666
28IRF1_19129219_ChIP-ChIP_H3396_Human1.90788874
29MYC_18358816_ChIP-ChIP_MESCs_Mouse1.90097073
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89881080
31VDR_23849224_ChIP-Seq_CD4+_Human1.88531725
32TP63_19390658_ChIP-ChIP_HaCaT_Human1.86302619
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.83551215
34FOXP3_21729870_ChIP-Seq_TREG_Human1.75028960
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.74994142
36ELK1_19687146_ChIP-ChIP_HELA_Human1.74448421
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.72111565
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.71061181
39P300_19829295_ChIP-Seq_ESCs_Human1.69630628
40MYC_19079543_ChIP-ChIP_MESCs_Mouse1.68761908
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66362728
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65548712
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.64051597
44DCP1A_22483619_ChIP-Seq_HELA_Human1.61446929
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59533255
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.51564872
47E2F1_21310950_ChIP-Seq_MCF-7_Human1.49873649
48POU5F1_16153702_ChIP-ChIP_HESCs_Human1.46996226
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.46092465
50TTF2_22483619_ChIP-Seq_HELA_Human1.45336063
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44186253
52ER_23166858_ChIP-Seq_MCF-7_Human1.42855539
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.39966380
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.39584106
55SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38313256
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37373185
57E2F1_18555785_ChIP-Seq_MESCs_Mouse1.36952739
58GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36477692
59EWS_26573619_Chip-Seq_HEK293_Human1.34098148
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32104190
61AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31938604
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.31493619
63FUS_26573619_Chip-Seq_HEK293_Human1.31240330
64XRN2_22483619_ChIP-Seq_HELA_Human1.28886445
65ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28774021
66PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28692551
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28404520
68KAP1_22055183_ChIP-Seq_ESCs_Mouse1.27728390
69TP53_22573176_ChIP-Seq_HFKS_Human1.27340122
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.27055397
71MYC_18940864_ChIP-ChIP_HL60_Human1.24498040
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.22862191
73EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.22701304
74CBP_20019798_ChIP-Seq_JUKART_Human1.22028179
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.22028179
76KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.20541607
77MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20373295
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20186474
79SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16729206
80RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.15766321
81EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.15669536
82FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.15501074
83NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12921678
84MYCN_18555785_ChIP-Seq_MESCs_Mouse1.12134850
85NFE2_27457419_Chip-Seq_LIVER_Mouse1.11920163
86PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11106193
87STAT3_23295773_ChIP-Seq_U87_Human1.10550862
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09350549
89* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09083016
90EZH2_22144423_ChIP-Seq_EOC_Human1.08148289
91KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06950820
92SMAD4_21799915_ChIP-Seq_A2780_Human1.06668124
93SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06433475
94OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05974215
95TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04288892
96GABP_19822575_ChIP-Seq_HepG2_Human1.03775925
97TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03736745
98SCL_19346495_ChIP-Seq_HPC-7_Human1.03554926
99SOX2_19829295_ChIP-Seq_ESCs_Human1.00793416
100NANOG_19829295_ChIP-Seq_ESCs_Human1.00793416
101GBX2_23144817_ChIP-Seq_PC3_Human1.00607973
102TAF15_26573619_Chip-Seq_HEK293_Human1.00556407
103AR_21909140_ChIP-Seq_LNCAP_Human1.00111496
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00057252
105TCF4_23295773_ChIP-Seq_U87_Human0.99831819
106SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99646557
107POU3F2_20337985_ChIP-ChIP_501MEL_Human0.98205031
108AR_25329375_ChIP-Seq_VCAP_Human0.98049409
109RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97799704
110SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97627752
111STAT3_18555785_Chip-Seq_ESCs_Mouse0.97032921
112POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95916983
113CIITA_25753668_ChIP-Seq_RAJI_Human0.94255595
114RNF2_27304074_Chip-Seq_NSC_Mouse0.93546676
115CRX_20693478_ChIP-Seq_RETINA_Mouse0.93514434
116SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93377313
117NANOG_18555785_Chip-Seq_ESCs_Mouse0.93368688
118FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93345173
119FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93267001
120PIAS1_25552417_ChIP-Seq_VCAP_Human0.92852453
121TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92820477
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92299606
123SMAD3_21741376_ChIP-Seq_EPCs_Human0.92268839
124HTT_18923047_ChIP-ChIP_STHdh_Human0.91013751
125SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90884221
126SOX2_16153702_ChIP-ChIP_HESCs_Human0.90527096
127EZH2_27294783_Chip-Seq_NPCs_Mouse0.89938435
128EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88642584
129POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.88483320
130PCGF2_27294783_Chip-Seq_NPCs_Mouse0.88131643
131LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.87766666
132EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.87682605
133IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.87300225
134NMYC_18555785_Chip-Seq_ESCs_Mouse0.87274833
135IRF8_21731497_ChIP-ChIP_J774_Mouse0.84766609
136P300_18555785_Chip-Seq_ESCs_Mouse0.84332875
137BMI1_23680149_ChIP-Seq_NPCS_Mouse0.83230976
138RBPJ_22232070_ChIP-Seq_NCS_Mouse0.82724299
139RUNX1_27457419_Chip-Seq_LIVER_Mouse0.81110931
140ZFX_18555785_Chip-Seq_ESCs_Mouse0.81066771
141TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.79932020

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.17973069
2MP0010094_abnormal_chromosome_stability3.60436775
3MP0000566_synostosis3.49495473
4MP0006292_abnormal_olfactory_placode3.46937140
5MP0001986_abnormal_taste_sensitivity3.45514870
6MP0003693_abnormal_embryo_hatching3.40142959
7MP0008058_abnormal_DNA_repair3.24701171
8MP0001188_hyperpigmentation2.98596950
9MP0003111_abnormal_nucleus_morphology2.81616542
10MP0002396_abnormal_hematopoietic_system2.70584254
11MP0008877_abnormal_DNA_methylation2.54156950
12MP0003077_abnormal_cell_cycle2.40267504
13MP0005174_abnormal_tail_pigmentation2.29825327
14MP0002132_abnormal_respiratory_system2.26794240
15MP0008007_abnormal_cellular_replicative2.21873703
16MP0004957_abnormal_blastocyst_morpholog2.11001334
17MP0002938_white_spotting2.09998777
18MP0005075_abnormal_melanosome_morpholog2.05505177
19MP0009379_abnormal_foot_pigmentation2.02993274
20MP0003136_yellow_coat_color1.98342570
21MP0003718_maternal_effect1.98257380
22MP0005409_darkened_coat_color1.97160231
23MP0005253_abnormal_eye_physiology1.92340015
24MP0002102_abnormal_ear_morphology1.91400576
25MP0000015_abnormal_ear_pigmentation1.85146806
26MP0005423_abnormal_somatic_nervous1.82665914
27MP0000569_abnormal_digit_pigmentation1.81614771
28MP0001529_abnormal_vocalization1.81412792
29MP0008789_abnormal_olfactory_epithelium1.72035101
30MP0003786_premature_aging1.71756902
31MP0002234_abnormal_pharynx_morphology1.69053857
32MP0002736_abnormal_nociception_after1.66673265
33MP0008932_abnormal_embryonic_tissue1.58332561
34MP0002095_abnormal_skin_pigmentation1.57211197
35MP0006276_abnormal_autonomic_nervous1.55858571
36MP0003890_abnormal_embryonic-extraembry1.55819112
37MP0003763_abnormal_thymus_physiology1.53605922
38MP0005410_abnormal_fertilization1.44222038
39MP0004381_abnormal_hair_follicle1.42535635
40MP0000490_abnormal_crypts_of1.41453928
41MP0005394_taste/olfaction_phenotype1.38811554
42MP0005499_abnormal_olfactory_system1.38811554
43MP0000372_irregular_coat_pigmentation1.36439158
44MP0001905_abnormal_dopamine_level1.36143204
45MP0000427_abnormal_hair_cycle1.35690241
46MP0001929_abnormal_gametogenesis1.35506810
47MP0002210_abnormal_sex_determination1.35266681
48MP0009046_muscle_twitch1.33329253
49MP0001968_abnormal_touch/_nociception1.25974573
50MP0003195_calcinosis1.25611585
51MP0003121_genomic_imprinting1.24709213
52MP0000647_abnormal_sebaceous_gland1.23225740
53MP0003950_abnormal_plasma_membrane1.23171987
54MP0006035_abnormal_mitochondrial_morpho1.22186666
55MP0005084_abnormal_gallbladder_morpholo1.18564104
56MP0003938_abnormal_ear_development1.16974578
57MP0003698_abnormal_male_reproductive1.16158056
58MP0005171_absent_coat_pigmentation1.14484363
59MP0001293_anophthalmia1.14072604
60MP0001835_abnormal_antigen_presentation1.13646147
61MP0003787_abnormal_imprinting1.10617257
62MP0002163_abnormal_gland_morphology1.10381690
63MP0002837_dystrophic_cardiac_calcinosis1.10179162
64MP0004147_increased_porphyrin_level1.09548881
65MP0004808_abnormal_hematopoietic_stem1.08591043
66MP0009697_abnormal_copulation1.07705923
67MP0001145_abnormal_male_reproductive1.07161097
68MP0005391_vision/eye_phenotype1.06590942
69MP0006036_abnormal_mitochondrial_physio1.06241011
70MP0005187_abnormal_penis_morphology1.05859041
71MP0003567_abnormal_fetal_cardiomyocyte1.05030698
72MP0003186_abnormal_redox_activity1.03750268
73MP0004043_abnormal_pH_regulation1.03626399
74MP0000653_abnormal_sex_gland1.03236903
75MP0002160_abnormal_reproductive_system1.00947680
76MP0004215_abnormal_myocardial_fiber0.99604566
77MP0001485_abnormal_pinna_reflex0.98652338
78MP0001119_abnormal_female_reproductive0.97874711
79MP0006054_spinal_hemorrhage0.97123832
80MP0003941_abnormal_skin_development0.96810177
81MP0005645_abnormal_hypothalamus_physiol0.96099683
82MP0000358_abnormal_cell_content/0.93587451
83MP0002398_abnormal_bone_marrow0.93126072
84MP0005379_endocrine/exocrine_gland_phen0.92623571
85MP0005671_abnormal_response_to0.91857549
86MP0002148_abnormal_hypersensitivity_rea0.91619124
87MP0001984_abnormal_olfaction0.91320809
88MP0009333_abnormal_splenocyte_physiolog0.90650060
89MP0001286_abnormal_eye_development0.90622160
90MP0004142_abnormal_muscle_tone0.89435947
91MP0004145_abnormal_muscle_electrophysio0.89345138
92MP0001324_abnormal_eye_pigmentation0.88956302
93MP0001764_abnormal_homeostasis0.87577915
94MP0005395_other_phenotype0.87528753
95MP0000313_abnormal_cell_death0.87207922
96MP0000465_gastrointestinal_hemorrhage0.87006630
97MP0000778_abnormal_nervous_system0.86624769
98MP0000689_abnormal_spleen_morphology0.86465605
99MP0002272_abnormal_nervous_system0.85449215
100MP0000383_abnormal_hair_follicle0.85029123
101MP0000049_abnormal_middle_ear0.84576863
102MP0005451_abnormal_body_composition0.84090890
103MP0005195_abnormal_posterior_eye0.83948184
104MP0003937_abnormal_limbs/digits/tail_de0.83918704
105MP0008995_early_reproductive_senescence0.83479430
106MP0000350_abnormal_cell_proliferation0.82824225
107MP0001486_abnormal_startle_reflex0.81941319
108MP0002277_abnormal_respiratory_mucosa0.80925364
109MP0005389_reproductive_system_phenotype0.79598809
110MP0009785_altered_susceptibility_to0.79577269
111MP0001800_abnormal_humoral_immune0.78316081
112MP0002019_abnormal_tumor_incidence0.77868627
113MP0002638_abnormal_pupillary_reflex0.77594493
114MP0002722_abnormal_immune_system0.77025461
115MP0003880_abnormal_central_pattern0.76612371
116MP0008872_abnormal_physiological_respon0.76542384
117MP0003806_abnormal_nucleotide_metabolis0.76091502
118MP0008775_abnormal_heart_ventricle0.75893274
119MP0002090_abnormal_vision0.75446263
120MP0002822_catalepsy0.75342601
121MP0000703_abnormal_thymus_morphology0.75318460
122MP0003119_abnormal_digestive_system0.74474311
123MP0002233_abnormal_nose_morphology0.74434218
124MP0002751_abnormal_autonomic_nervous0.74425571
125MP0002161_abnormal_fertility/fecundity0.73483883
126MP0003646_muscle_fatigue0.72816187
127MP0000716_abnormal_immune_system0.72305277
128MP0002420_abnormal_adaptive_immunity0.72060222
129MP0005367_renal/urinary_system_phenotyp0.72038057
130MP0000516_abnormal_urinary_system0.72038057
131MP0001697_abnormal_embryo_size0.71878997
132MP0005397_hematopoietic_system_phenotyp0.71030161
133MP0001545_abnormal_hematopoietic_system0.71030161
134MP0000631_abnormal_neuroendocrine_gland0.70357365
135MP0006072_abnormal_retinal_apoptosis0.70137846
136MP0001819_abnormal_immune_cell0.69952730
137MP0002429_abnormal_blood_cell0.69737758
138MP0003123_paternal_imprinting0.68827062
139MP0000026_abnormal_inner_ear0.68081092
140MP0000462_abnormal_digestive_system0.67782648
141MP0005551_abnormal_eye_electrophysiolog0.67317198
142MP0005646_abnormal_pituitary_gland0.67292109
143MP0001963_abnormal_hearing_physiology0.66750560
144MP0005000_abnormal_immune_tolerance0.65052316
145MP0004133_heterotaxia0.64746055
146MP0002452_abnormal_antigen_presenting0.64175916
147MP0002723_abnormal_immune_serum0.64156491

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.98849837
2Chromsome breakage (HP:0040012)4.74897985
3Supernumerary spleens (HP:0009799)4.13318907
4Birth length less than 3rd percentile (HP:0003561)3.80911490
5Abnormality of the preputium (HP:0100587)3.41886806
6Aplastic anemia (HP:0001915)3.32966921
7Abnormality of chromosome stability (HP:0003220)3.31819262
8Reticulocytopenia (HP:0001896)3.19810530
9Meckel diverticulum (HP:0002245)3.15278473
10Breast hypoplasia (HP:0003187)3.03921855
11Abnormality of the ileum (HP:0001549)2.98747841
12Abnormality of the renal collecting system (HP:0004742)2.92455463
13Duplicated collecting system (HP:0000081)2.91683458
14Increased hepatocellular lipid droplets (HP:0006565)2.89977408
15Aplasia/Hypoplasia of the uvula (HP:0010293)2.89727329
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.82498898
17Pancreatic fibrosis (HP:0100732)2.78968200
18Type I transferrin isoform profile (HP:0003642)2.77547594
19Abnormality of cells of the erythroid lineage (HP:0012130)2.76703087
20Abnormal number of erythroid precursors (HP:0012131)2.76665863
21Acute encephalopathy (HP:0006846)2.74330896
22Bone marrow hypocellularity (HP:0005528)2.73661378
23Congenital primary aphakia (HP:0007707)2.72554797
24Abnormal lung lobation (HP:0002101)2.68974361
25Gait imbalance (HP:0002141)2.65378854
26Abnormality of alanine metabolism (HP:0010916)2.62610702
27Hyperalaninemia (HP:0003348)2.62610702
28Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.62610702
29True hermaphroditism (HP:0010459)2.58903626
30Renal Fanconi syndrome (HP:0001994)2.58461123
31Dynein arm defect of respiratory motile cilia (HP:0012255)2.55775311
32Absent/shortened dynein arms (HP:0200106)2.55775311
33Intestinal atresia (HP:0011100)2.51427182
34Pancreatic cysts (HP:0001737)2.50442709
35White forelock (HP:0002211)2.49106030
36Exertional dyspnea (HP:0002875)2.48165218
37Abnormal mitochondria in muscle tissue (HP:0008316)2.47728167
38Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.46756883
39Abnormality of the renal medulla (HP:0100957)2.46665058
40Colon cancer (HP:0003003)2.45321069
41Duplication of thumb phalanx (HP:0009942)2.44702338
42Increased CSF lactate (HP:0002490)2.43227424
43Duodenal stenosis (HP:0100867)2.43071184
44Small intestinal stenosis (HP:0012848)2.43071184
45Nephrogenic diabetes insipidus (HP:0009806)2.42901017
46Myelodysplasia (HP:0002863)2.42058841
47Aplasia/Hypoplasia of the tibia (HP:0005772)2.41636570
48Clubbing of toes (HP:0100760)2.41445161
49Patchy hypopigmentation of hair (HP:0011365)2.41128014
50Molar tooth sign on MRI (HP:0002419)2.40387819
51Abnormality of midbrain morphology (HP:0002418)2.40387819
52Progressive macrocephaly (HP:0004481)2.40328055
53Abnormality of the renal cortex (HP:0011035)2.38998998
54Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.38298960
55Chronic hepatic failure (HP:0100626)2.37269382
56Abnormal respiratory epithelium morphology (HP:0012253)2.37256292
57Abnormal respiratory motile cilium morphology (HP:0005938)2.37256292
58Fair hair (HP:0002286)2.36195373
59Abnormality of DNA repair (HP:0003254)2.32126232
60Renal cortical cysts (HP:0000803)2.31281846
61Nephroblastoma (Wilms tumor) (HP:0002667)2.28617865
62Hyperglycinemia (HP:0002154)2.28489750
63Methylmalonic acidemia (HP:0002912)2.27042878
64Patellar aplasia (HP:0006443)2.26998213
65Parakeratosis (HP:0001036)2.26504928
66Genital tract atresia (HP:0001827)2.26035069
67Abnormal hair whorl (HP:0010721)2.25937377
68Type II lissencephaly (HP:0007260)2.25818801
693-Methylglutaconic aciduria (HP:0003535)2.25344455
70Lipid accumulation in hepatocytes (HP:0006561)2.22280818
71IgM deficiency (HP:0002850)2.22251046
72Abnormality of the heme biosynthetic pathway (HP:0010472)2.21621290
73Reduced antithrombin III activity (HP:0001976)2.20924551
74Abnormal ciliary motility (HP:0012262)2.20290319
75Short tibia (HP:0005736)2.19148777
76Vaginal atresia (HP:0000148)2.18795183
77Astigmatism (HP:0000483)2.14184487
78Small hand (HP:0200055)2.13102560
79Aplasia/Hypoplasia of the patella (HP:0006498)2.10610327
80Aplasia/Hypoplasia of the tongue (HP:0010295)2.09729322
81Asplenia (HP:0001746)2.09178802
82Hyperventilation (HP:0002883)2.09132249
83Cerebellar dysplasia (HP:0007033)2.08978047
84Sclerocornea (HP:0000647)2.08435124
85Impulsivity (HP:0100710)2.08435100
86Sloping forehead (HP:0000340)2.08433841
8711 pairs of ribs (HP:0000878)2.08315365
88Embryonal renal neoplasm (HP:0011794)2.07550908
89Acute myeloid leukemia (HP:0004808)2.07451443
90Hepatocellular necrosis (HP:0001404)2.07432608
91Abnormal respiratory motile cilium physiology (HP:0012261)2.05630602
92Premature graying of hair (HP:0002216)2.05275753
93Triphalangeal thumb (HP:0001199)2.04029562
94Abnormality of the labia minora (HP:0012880)2.00791257
95Postaxial foot polydactyly (HP:0001830)2.00489661
96Pendular nystagmus (HP:0012043)1.99381052
97Poor coordination (HP:0002370)1.97463397
98Hepatic necrosis (HP:0002605)1.97394878
99Microvesicular hepatic steatosis (HP:0001414)1.97215229
100Pallor (HP:0000980)1.95681728
101Increased serum lactate (HP:0002151)1.95641081
102Postaxial hand polydactyly (HP:0001162)1.95471089
103Abnormality of the carotid arteries (HP:0005344)1.94695261
104Abnormality of the duodenum (HP:0002246)1.93575061
105Anencephaly (HP:0002323)1.89929922
106Preaxial hand polydactyly (HP:0001177)1.89200147
107Cystic liver disease (HP:0006706)1.88683221
108Abnormality of the prostate (HP:0008775)1.88294236
109Dandy-Walker malformation (HP:0001305)1.88144389
110Retinal dysplasia (HP:0007973)1.88081770
111Acute necrotizing encephalopathy (HP:0006965)1.86655690
112Abnormal spermatogenesis (HP:0008669)1.85373618
113Congenital hepatic fibrosis (HP:0002612)1.85208672
114Attenuation of retinal blood vessels (HP:0007843)1.85163032
115Absent thumb (HP:0009777)1.84344100
116Cerebral edema (HP:0002181)1.84326921
117Gaze-evoked nystagmus (HP:0000640)1.83796266
118Cortical dysplasia (HP:0002539)1.83724902
119Lissencephaly (HP:0001339)1.83538853
120Aganglionic megacolon (HP:0002251)1.82928718
121Abnormal number of incisors (HP:0011064)1.81500990
122Tubulointerstitial nephritis (HP:0001970)1.81048642
123Bifid tongue (HP:0010297)1.81043117
124Aplasia/Hypoplasia of the spleen (HP:0010451)1.80518673
125Absent radius (HP:0003974)1.80359836
126Pancytopenia (HP:0001876)1.79997637
127Abnormality of renal resorption (HP:0011038)1.79812069
128Congenital stationary night blindness (HP:0007642)1.77433462
129Abnormality of the septum pellucidum (HP:0007375)1.76915403
130Squamous cell carcinoma (HP:0002860)1.76690823
131Oligohydramnios (HP:0001562)1.76651675
132Abnormality of the pons (HP:0007361)1.76218661
133Medial flaring of the eyebrow (HP:0010747)1.75978382
134Hypoplasia of the pons (HP:0012110)1.75774375
135Lymphoma (HP:0002665)1.74981999
136Abnormality of serum amino acid levels (HP:0003112)1.74676179
137Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.74612596
138Abnormal protein N-linked glycosylation (HP:0012347)1.74612596
139Abnormal protein glycosylation (HP:0012346)1.74612596
140Abnormal glycosylation (HP:0012345)1.74612596
141Multicystic kidney dysplasia (HP:0000003)1.74497861
142Ectopic kidney (HP:0000086)1.73766232
143Volvulus (HP:0002580)1.72824689
144Methylmalonic aciduria (HP:0012120)1.72820119
145Macrocytic anemia (HP:0001972)1.72574301
146Male pseudohermaphroditism (HP:0000037)1.72283488
147Adrenal hypoplasia (HP:0000835)1.72024177
148Nephronophthisis (HP:0000090)1.71777383
149Median cleft lip (HP:0000161)1.70844545
150Specific learning disability (HP:0001328)1.70497148
151Aplasia involving forearm bones (HP:0009822)1.69380207
152Absent forearm bone (HP:0003953)1.69380207
153Mitochondrial inheritance (HP:0001427)1.69145070
154Septo-optic dysplasia (HP:0100842)1.68914348
155Tubular atrophy (HP:0000092)1.68683422
156Glioma (HP:0009733)1.66248547
157Oculomotor apraxia (HP:0000657)1.65820522
158Oligodactyly (hands) (HP:0001180)1.65124543
159Prominent nasal bridge (HP:0000426)1.64916824

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.63120592
2BUB13.09641233
3PLK42.98421439
4MAP4K22.70873601
5FRK2.64643104
6NUAK12.63616171
7WEE12.61520201
8CDC72.52357318
9WNK32.45982995
10TTK2.39415578
11NEK12.36053982
12SRPK12.27169163
13IRAK42.01487702
14MAP3K41.92281356
15ZAK1.87965692
16CLK11.80023073
17MST41.79969041
18TRIM281.76357162
19VRK11.76162677
20YES11.72773721
21ADRBK21.71729729
22MKNK11.68829433
23CASK1.66131011
24PINK11.65819237
25TXK1.65417375
26KIT1.62111943
27BCR1.59246850
28STK241.53550274
29ERBB31.49767016
30VRK21.49111676
31EIF2AK21.49002219
32MAPK131.48885934
33NEK61.43558454
34MKNK21.43019024
35EIF2AK11.42813604
36BRSK21.42569619
37PLK11.42083224
38BMPR21.37656613
39DYRK21.34668426
40TNIK1.33667129
41CHEK21.32640512
42CDK71.28602943
43NEK21.23560097
44ATR1.23026408
45PIM21.20465866
46STK31.20388236
47IRAK31.18346144
48MAPKAPK51.18001162
49PLK31.16043950
50TEC1.16033903
51BCKDK1.14369272
52GRK11.13983057
53CSNK1G21.11675375
54EIF2AK31.10903012
55BMPR1B1.10281904
56DYRK31.09083638
57ACVR1B1.08310173
58PNCK1.07896630
59WNK41.05420341
60PRPF4B1.00040051
61AURKB0.97971386
62TAF10.97355171
63UHMK10.95720728
64CDK80.94874138
65CDK30.93351989
66BRAF0.92189411
67STK390.89055869
68PASK0.88824051
69STK40.87602422
70MAP2K70.87189647
71MUSK0.86154689
72NME20.85621983
73NME10.84782125
74CCNB10.83997878
75MATK0.83791512
76RPS6KB20.83270770
77AKT30.80929856
78BTK0.80783431
79CDK90.78140787
80MAP3K120.77229419
81TAOK30.76314245
82TLK10.76181704
83TIE10.75975867
84FES0.74906833
85PAK30.74114361
86MAP4K10.72860988
87RPS6KA50.71158743
88ATM0.71157533
89CHEK10.70136933
90TGFBR10.66476511
91STK38L0.66243189
92MARK10.66118341
93LYN0.65054171
94TSSK60.64229816
95PIM10.62365830
96BLK0.61485964
97PKN10.61391334
98BRSK10.61336195
99PRKCE0.61225978
100AURKA0.60929338
101CSNK1G30.60099025
102OXSR10.57016247
103CSNK1G10.56241717
104IRAK20.56100596
105RPS6KA40.55975883
106CSNK2A10.55767414
107TAOK20.54633427
108JAK30.54237736
109FLT30.53344020
110TRPM70.51989142
111MAP3K140.51640765
112NTRK20.51581826
113SIK20.50554268
114PRKCG0.48657865
115CDK40.48546193
116PTK2B0.48486602
117PBK0.48235942
118CDK10.48234198
119SYK0.48103351
120CSNK2A20.47627286
121CSNK1A1L0.47421912
122PLK20.47251383
123INSRR0.47001175
124MAP3K60.45955765
125GRK70.45553632
126MINK10.45253549
127MAPK40.44681648
128PDK20.44311033
129BRD40.44026181
130LATS10.43556654
131LCK0.41940535
132ADRBK10.41552916
133EPHA40.34827212
134CSNK1D0.34404055
135PRKD30.32904938
136OBSCN0.32022091
137CSNK1A10.31580700
138PRKACB0.28096566
139CAMK2A0.27356449
140CAMKK20.25897404

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.50577632
2Mismatch repair_Homo sapiens_hsa034304.13059855
3Homologous recombination_Homo sapiens_hsa034403.59431129
4Fanconi anemia pathway_Homo sapiens_hsa034603.37382814
5RNA polymerase_Homo sapiens_hsa030203.33431798
6Ribosome_Homo sapiens_hsa030103.25729409
7Nucleotide excision repair_Homo sapiens_hsa034202.82890574
8Base excision repair_Homo sapiens_hsa034102.67058191
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.59761144
10Basal transcription factors_Homo sapiens_hsa030222.47340217
11Pyrimidine metabolism_Homo sapiens_hsa002402.46128659
12Non-homologous end-joining_Homo sapiens_hsa034502.45107607
13Spliceosome_Homo sapiens_hsa030402.44587394
14Proteasome_Homo sapiens_hsa030502.41041557
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.39558835
16RNA degradation_Homo sapiens_hsa030182.27137680
17Cell cycle_Homo sapiens_hsa041102.26398841
18Propanoate metabolism_Homo sapiens_hsa006402.08828089
19Butanoate metabolism_Homo sapiens_hsa006501.90882254
20RNA transport_Homo sapiens_hsa030131.85596929
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.79414759
22Protein export_Homo sapiens_hsa030601.75045491
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.61184920
24One carbon pool by folate_Homo sapiens_hsa006701.60764277
25Purine metabolism_Homo sapiens_hsa002301.56522977
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.52714450
27Oxidative phosphorylation_Homo sapiens_hsa001901.52198072
28Selenocompound metabolism_Homo sapiens_hsa004501.47075583
29Ether lipid metabolism_Homo sapiens_hsa005651.33349659
30Huntingtons disease_Homo sapiens_hsa050161.33107083
31Parkinsons disease_Homo sapiens_hsa050121.32245126
32p53 signaling pathway_Homo sapiens_hsa041151.29431574
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.21320962
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.21260165
35Arachidonic acid metabolism_Homo sapiens_hsa005901.19353527
36Linoleic acid metabolism_Homo sapiens_hsa005911.15287598
37Peroxisome_Homo sapiens_hsa041461.15039544
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.12937207
39Vitamin B6 metabolism_Homo sapiens_hsa007501.12299795
40mRNA surveillance pathway_Homo sapiens_hsa030151.02703989
41Nicotine addiction_Homo sapiens_hsa050331.01753686
42Primary immunodeficiency_Homo sapiens_hsa053401.00598330
43Primary bile acid biosynthesis_Homo sapiens_hsa001200.99121268
44Nitrogen metabolism_Homo sapiens_hsa009100.96986918
45Sphingolipid metabolism_Homo sapiens_hsa006000.94973896
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94736715
47Alzheimers disease_Homo sapiens_hsa050100.90893255
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89428983
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86694113
50Olfactory transduction_Homo sapiens_hsa047400.84398340
51Pyruvate metabolism_Homo sapiens_hsa006200.84172846
52Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.83469818
53Hematopoietic cell lineage_Homo sapiens_hsa046400.81700132
54Phototransduction_Homo sapiens_hsa047440.79576307
55Tryptophan metabolism_Homo sapiens_hsa003800.79572971
56Sulfur metabolism_Homo sapiens_hsa009200.78047358
57Folate biosynthesis_Homo sapiens_hsa007900.77563517
58Herpes simplex infection_Homo sapiens_hsa051680.76306362
59Epstein-Barr virus infection_Homo sapiens_hsa051690.74708187
60NF-kappa B signaling pathway_Homo sapiens_hsa040640.74224905
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73102694
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72934513
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72793972
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71487606
65Systemic lupus erythematosus_Homo sapiens_hsa053220.70499796
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70458778
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67882861
68Fatty acid metabolism_Homo sapiens_hsa012120.67615113
69Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.67361013
70Intestinal immune network for IgA production_Homo sapiens_hsa046720.66991501
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.64444059
72Asthma_Homo sapiens_hsa053100.61952578
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61556865
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.60926742
75Allograft rejection_Homo sapiens_hsa053300.60846273
76Steroid hormone biosynthesis_Homo sapiens_hsa001400.59637480
77Circadian rhythm_Homo sapiens_hsa047100.58924783
78beta-Alanine metabolism_Homo sapiens_hsa004100.57069064
79Measles_Homo sapiens_hsa051620.56876067
80Autoimmune thyroid disease_Homo sapiens_hsa053200.56300260
81Caffeine metabolism_Homo sapiens_hsa002320.54341387
82Chemical carcinogenesis_Homo sapiens_hsa052040.53997932
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.53166948
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52935357
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48769918
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47050332
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46361149
88Serotonergic synapse_Homo sapiens_hsa047260.45904084
89Metabolic pathways_Homo sapiens_hsa011000.45669415
90Fatty acid elongation_Homo sapiens_hsa000620.45482763
91Oocyte meiosis_Homo sapiens_hsa041140.45480741
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44940438
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44034121
94Retinol metabolism_Homo sapiens_hsa008300.43069752
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42821374
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.41030866
97Ovarian steroidogenesis_Homo sapiens_hsa049130.40316622
98NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40205657
99Viral carcinogenesis_Homo sapiens_hsa052030.38537034
100Taste transduction_Homo sapiens_hsa047420.38533215
101Fatty acid degradation_Homo sapiens_hsa000710.38027627
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.37610688
103GABAergic synapse_Homo sapiens_hsa047270.37193152
104Arginine and proline metabolism_Homo sapiens_hsa003300.36659795
105Glutathione metabolism_Homo sapiens_hsa004800.36095286
106Collecting duct acid secretion_Homo sapiens_hsa049660.34967067
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.32712381
108Cardiac muscle contraction_Homo sapiens_hsa042600.32012217
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31560982
110Steroid biosynthesis_Homo sapiens_hsa001000.31037890
111Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30040028
112ABC transporters_Homo sapiens_hsa020100.28989078
113TGF-beta signaling pathway_Homo sapiens_hsa043500.28025294
114Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.26971858
115Morphine addiction_Homo sapiens_hsa050320.25819658
116Graft-versus-host disease_Homo sapiens_hsa053320.25774283
117Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.25316709
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.25300105
119Alcoholism_Homo sapiens_hsa050340.20965730
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.20755201
121HTLV-I infection_Homo sapiens_hsa051660.20055097
122Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.19653231
123N-Glycan biosynthesis_Homo sapiens_hsa005100.19288983
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.18137282
125Histidine metabolism_Homo sapiens_hsa003400.16860351
126Pentose phosphate pathway_Homo sapiens_hsa000300.16403277
127Vitamin digestion and absorption_Homo sapiens_hsa049770.16240918
128Sulfur relay system_Homo sapiens_hsa041220.15239765
129Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.14524330
130Drug metabolism - other enzymes_Homo sapiens_hsa009830.14495721
131Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.13045890
132Legionellosis_Homo sapiens_hsa051340.11549661
133Malaria_Homo sapiens_hsa051440.10735526
134Regulation of autophagy_Homo sapiens_hsa041400.10298941
135Jak-STAT signaling pathway_Homo sapiens_hsa046300.09752582
136Hedgehog signaling pathway_Homo sapiens_hsa043400.09203551
137Apoptosis_Homo sapiens_hsa042100.08787343
138Cysteine and methionine metabolism_Homo sapiens_hsa002700.07684583
139Pathways in cancer_Homo sapiens_hsa052000.07556481

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »