CEP70

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1CENP-A containing nucleosome assembly (GO:0034080)4.42810796
2chromatin remodeling at centromere (GO:0031055)4.38066538
3centriole replication (GO:0007099)4.34316073
4microtubule depolymerization (GO:0007019)4.18253555
5DNA replication-independent nucleosome organization (GO:0034724)4.08119049
6DNA replication-independent nucleosome assembly (GO:0006336)4.08119049
7mitotic metaphase plate congression (GO:0007080)3.96032392
8kinetochore organization (GO:0051383)3.94686513
9attachment of spindle microtubules to kinetochore (GO:0008608)3.82155479
10kinetochore assembly (GO:0051382)3.80440120
11metaphase plate congression (GO:0051310)3.76174354
12histone exchange (GO:0043486)3.73900157
13DNA topological change (GO:0006265)3.67806659
14establishment of chromosome localization (GO:0051303)3.58210043
15replication fork processing (GO:0031297)3.57535733
16regulation of spindle organization (GO:0090224)3.55977508
17meiotic chromosome segregation (GO:0045132)3.51392263
18mitotic sister chromatid segregation (GO:0000070)3.49712178
19maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.48641659
20regulation of mitotic spindle organization (GO:0060236)3.42514886
21telomere maintenance via recombination (GO:0000722)3.42212051
22piRNA metabolic process (GO:0034587)3.32259048
23DNA replication checkpoint (GO:0000076)3.30822158
24positive regulation of mitotic sister chromatid separation (GO:1901970)3.25884538
25positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.25884538
26positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.25884538
27maturation of 5.8S rRNA (GO:0000460)3.25446925
28intraciliary transport (GO:0042073)3.23883138
29telomere maintenance via semi-conservative replication (GO:0032201)3.23710873
30histone H2A acetylation (GO:0043968)3.19878589
31regulation of nuclear cell cycle DNA replication (GO:0033262)3.19817147
32mitotic recombination (GO:0006312)3.19263414
33regulation of sister chromatid segregation (GO:0033045)3.19261408
34regulation of mitotic sister chromatid separation (GO:0010965)3.19261408
35regulation of mitotic sister chromatid segregation (GO:0033047)3.19261408
36spindle assembly checkpoint (GO:0071173)3.15340408
37DNA double-strand break processing (GO:0000729)3.15219920
38negative regulation of mitotic sister chromatid separation (GO:2000816)3.14761933
39negative regulation of mitotic sister chromatid segregation (GO:0033048)3.14761933
40negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.14761933
41negative regulation of sister chromatid segregation (GO:0033046)3.14761933
42regulation of centriole replication (GO:0046599)3.14078793
43sister chromatid segregation (GO:0000819)3.12416029
44DNA replication initiation (GO:0006270)3.12342023
45negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.11338082
46regulation of mitotic metaphase/anaphase transition (GO:0030071)3.10124502
47mitotic spindle assembly checkpoint (GO:0007094)3.09315598
48spindle checkpoint (GO:0031577)3.08628567
49regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07584195
50negative regulation of chromosome segregation (GO:0051985)3.07488398
51establishment of integrated proviral latency (GO:0075713)3.02672483
52viral mRNA export from host cell nucleus (GO:0046784)3.02545748
53chromosome segregation (GO:0007059)3.02161148
54centriole assembly (GO:0098534)3.00599465
55male meiosis (GO:0007140)2.99686303
56regulation of centrosome duplication (GO:0010824)2.98065988
57protein K6-linked ubiquitination (GO:0085020)2.96621935
58nucleotide-excision repair, DNA gap filling (GO:0006297)2.96442421
59regulation of chromosome segregation (GO:0051983)2.96105636
60poly(A)+ mRNA export from nucleus (GO:0016973)2.94598202
61resolution of meiotic recombination intermediates (GO:0000712)2.93267732
62intra-S DNA damage checkpoint (GO:0031573)2.91978209
63protein localization to chromosome (GO:0034502)2.91282351
64mitotic chromosome condensation (GO:0007076)2.91082085
65microtubule polymerization or depolymerization (GO:0031109)2.90122375
66mitotic spindle checkpoint (GO:0071174)2.88873162
67DNA strand elongation involved in DNA replication (GO:0006271)2.87355487
68proteasome assembly (GO:0043248)2.85714331
69DNA synthesis involved in DNA repair (GO:0000731)2.84306294
707-methylguanosine mRNA capping (GO:0006370)2.84178799
71regulation of sister chromatid cohesion (GO:0007063)2.83342940
72negative regulation of meiosis (GO:0045835)2.81899166
73negative regulation of DNA recombination (GO:0045910)2.81501879
74DNA strand renaturation (GO:0000733)2.81211442
75mitotic G2/M transition checkpoint (GO:0044818)2.80980248
76synapsis (GO:0007129)2.80869922
77negative regulation of DNA-dependent DNA replication (GO:2000104)2.80530039
78DNA strand elongation (GO:0022616)2.79571922
79RNA capping (GO:0036260)2.76682861
807-methylguanosine RNA capping (GO:0009452)2.76682861
81exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.76270879
82nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.76188029
83regulation of mitotic spindle checkpoint (GO:1903504)2.75752497
84regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.75752497
85mitotic spindle organization (GO:0007052)2.75680202
86mismatch repair (GO:0006298)2.74037997
87protein localization to kinetochore (GO:0034501)2.73672924
88negative regulation of mitosis (GO:0045839)2.73558118
89axonemal dynein complex assembly (GO:0070286)2.73266877
90rRNA modification (GO:0000154)2.72048206
91DNA replication-dependent nucleosome assembly (GO:0006335)2.71997843
92DNA replication-dependent nucleosome organization (GO:0034723)2.71997843
93mitotic sister chromatid cohesion (GO:0007064)2.71554608
94rRNA methylation (GO:0031167)2.70404149
95transcription-coupled nucleotide-excision repair (GO:0006283)2.70259083
96spindle assembly involved in mitosis (GO:0090307)2.70160247
97sister chromatid cohesion (GO:0007062)2.70091716
98transcription elongation from RNA polymerase II promoter (GO:0006368)2.69992440
99meiotic cell cycle (GO:0051321)2.68856943
100nuclear pore organization (GO:0006999)2.67452087
101double-strand break repair via nonhomologous end joining (GO:0006303)2.66760606
102non-recombinational repair (GO:0000726)2.66760606
103protein localization to chromosome, centromeric region (GO:0071459)2.66669967
104respiratory chain complex IV assembly (GO:0008535)2.66669698
105DNA ligation (GO:0006266)2.66636627
106nuclear pore complex assembly (GO:0051292)2.66171333
107regulation of centrosome cycle (GO:0046605)2.65643765
108cullin deneddylation (GO:0010388)2.65642860
109regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.64688282
110ATP-dependent chromatin remodeling (GO:0043044)2.63894496
111purine nucleobase biosynthetic process (GO:0009113)2.63352533
112chromatin assembly or disassembly (GO:0006333)2.62728552
113spermatid nucleus differentiation (GO:0007289)2.62653725
114anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.62380716
115cilium or flagellum-dependent cell motility (GO:0001539)2.62275821
116DNA methylation involved in gamete generation (GO:0043046)2.61835000
117regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.60879023
118regulation of double-strand break repair via homologous recombination (GO:0010569)2.59993430
119centrosome organization (GO:0051297)2.59250180
120otic vesicle formation (GO:0030916)2.59171377
121RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.57869193
122positive regulation of chromosome segregation (GO:0051984)2.56971790
123meiotic nuclear division (GO:0007126)2.56799378
124nucleobase biosynthetic process (GO:0046112)2.56700125
125telomere maintenance via telomere lengthening (GO:0010833)2.53944656
126regulation of meiosis I (GO:0060631)2.52215772
127protein-DNA complex assembly (GO:0065004)2.52190604
128organelle disassembly (GO:1903008)2.51370918
129positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.46948585
130negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.46258853
131mitotic G2 DNA damage checkpoint (GO:0007095)2.46186526
132mitotic nuclear envelope disassembly (GO:0007077)2.45098492
133branched-chain amino acid catabolic process (GO:0009083)2.44209299
134negative regulation of nuclear division (GO:0051784)2.44031031
135mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.43293942
136microtubule organizing center organization (GO:0031023)2.39649676
137nonmotile primary cilium assembly (GO:0035058)2.38087466
138protein K11-linked ubiquitination (GO:0070979)2.36209305
139negative regulation of cell division (GO:0051782)2.35859082
140microtubule anchoring (GO:0034453)2.34920740

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.38009240
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.72789279
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.21492614
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.12327044
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.09886433
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.06902845
7FOXM1_23109430_ChIP-Seq_U2OS_Human3.04210105
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.96871874
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.87446734
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.80922357
11* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79889444
12VDR_22108803_ChIP-Seq_LS180_Human2.49300657
13PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.43323373
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.42277996
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.41760116
16VDR_23849224_ChIP-Seq_CD4+_Human2.33102081
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.29163971
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.26526119
19RBPJ_22232070_ChIP-Seq_NCS_Mouse2.24883457
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24813543
21ZNF274_21170338_ChIP-Seq_K562_Hela2.19087729
22* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.18190822
23EZH2_22144423_ChIP-Seq_EOC_Human2.12155588
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.11574005
25THAP11_20581084_ChIP-Seq_MESCs_Mouse2.06657602
26YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.99591782
27ELK1_19687146_ChIP-ChIP_HELA_Human1.98093053
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.94780833
29KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.94358856
30FOXP3_21729870_ChIP-Seq_TREG_Human1.94055716
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.85112783
32HOXB4_20404135_ChIP-ChIP_EML_Mouse1.84567126
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.81239989
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81019588
35MYC_19030024_ChIP-ChIP_MESCs_Mouse1.80373199
36SRF_21415370_ChIP-Seq_HL-1_Mouse1.76754874
37CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.74045706
38* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.72216596
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.69997519
40DCP1A_22483619_ChIP-Seq_HELA_Human1.68307794
41NELFA_20434984_ChIP-Seq_ESCs_Mouse1.64548619
42P300_19829295_ChIP-Seq_ESCs_Human1.64174156
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.63132836
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.61726610
45GABP_19822575_ChIP-Seq_HepG2_Human1.61475707
46PADI4_21655091_ChIP-ChIP_MCF-7_Human1.58805687
47FUS_26573619_Chip-Seq_HEK293_Human1.57911192
48E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.55344926
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.55239487
50FLI1_27457419_Chip-Seq_LIVER_Mouse1.50335025
51E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50260747
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.49362042
53CIITA_25753668_ChIP-Seq_RAJI_Human1.45790642
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.45384804
55* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45197854
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45043743
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.44669849
58GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.44177223
59MYC_19079543_ChIP-ChIP_MESCs_Mouse1.41368536
60EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.39903084
61* XRN2_22483619_ChIP-Seq_HELA_Human1.39668362
62EWS_26573619_Chip-Seq_HEK293_Human1.36580478
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.35526089
64GBX2_23144817_ChIP-Seq_PC3_Human1.35019152
65PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34915443
66FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34876385
67DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.33916694
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33342557
69ER_23166858_ChIP-Seq_MCF-7_Human1.31786170
70TTF2_22483619_ChIP-Seq_HELA_Human1.30540507
71* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.29619386
72IRF1_19129219_ChIP-ChIP_H3396_Human1.29346522
73SALL1_21062744_ChIP-ChIP_HESCs_Human1.26820067
74* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26697318
75RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.25879175
76NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24517896
77IGF1R_20145208_ChIP-Seq_DFB_Human1.22223674
78PCGF2_27294783_Chip-Seq_ESCs_Mouse1.21450618
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18452274
80* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.18327463
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17764834
82ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15061021
83SOX2_16153702_ChIP-ChIP_HESCs_Human1.14849642
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.13921165
85SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13485862
86ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12152121
87MYC_18940864_ChIP-ChIP_HL60_Human1.11567185
88CBP_20019798_ChIP-Seq_JUKART_Human1.11260565
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11260565
90MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08573817
91SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08132560
92NANOG_16153702_ChIP-ChIP_HESCs_Human1.08068667
93SMAD4_21799915_ChIP-Seq_A2780_Human1.07856496
94* SMAD3_21741376_ChIP-Seq_EPCs_Human1.06664341
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05052802
96EZH2_27294783_Chip-Seq_NPCs_Mouse1.04874775
97OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04362602
98TAF15_26573619_Chip-Seq_HEK293_Human1.04032462
99GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01154968
100EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00709715
101KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99300118
102ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98823506
103TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98392743
104PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97701148
105* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97233583
106E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97097919
107POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97038179
108BCAT_22108803_ChIP-Seq_LS180_Human0.96864141
109KDM5A_27292631_Chip-Seq_BREAST_Human0.96635931
110* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96135154
111SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95906379
112TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95567897
113FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95325702
114SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95203900
115KAP1_22055183_ChIP-Seq_ESCs_Mouse0.94428268
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94384218
117CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94279065
118AR_21909140_ChIP-Seq_LNCAP_Human0.93657147
119NANOG_18555785_Chip-Seq_ESCs_Mouse0.93625986
120CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.92280718
121NANOG_18555785_ChIP-Seq_MESCs_Mouse0.92149702
122SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92016506
123STAT3_23295773_ChIP-Seq_U87_Human0.91026092
124RNF2_27304074_Chip-Seq_NSC_Mouse0.90153542
125HTT_18923047_ChIP-ChIP_STHdh_Human0.89791198
126* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.89768301
127GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89713794
128NFE2_27457419_Chip-Seq_LIVER_Mouse0.89527057
129EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89373785
130POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.88927832
131TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88503584
132* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.86986391
133HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85085564
134CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.84841764
135GATA1_22025678_ChIP-Seq_K562_Human0.84675541
136TP53_22573176_ChIP-Seq_HFKS_Human0.84609913
137MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.81872784
138CTBP2_25329375_ChIP-Seq_LNCAP_Human0.81176765
139CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.78623397

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.26317035
2MP0003787_abnormal_imprinting3.85412268
3MP0008877_abnormal_DNA_methylation3.64176482
4MP0008057_abnormal_DNA_replication3.46433347
5MP0010094_abnormal_chromosome_stability3.37034566
6MP0006292_abnormal_olfactory_placode3.36514484
7MP0008058_abnormal_DNA_repair3.12790800
8MP0003111_abnormal_nucleus_morphology2.89991566
9MP0003077_abnormal_cell_cycle2.64912102
10MP0004957_abnormal_blastocyst_morpholog2.46288138
11MP0008007_abnormal_cellular_replicative2.32806868
12MP0003121_genomic_imprinting2.32358955
13MP0005646_abnormal_pituitary_gland2.24124532
14MP0000015_abnormal_ear_pigmentation2.06406490
15MP0005379_endocrine/exocrine_gland_phen2.01750473
16MP0001986_abnormal_taste_sensitivity1.99653247
17MP0001293_anophthalmia1.97510935
18MP0003123_paternal_imprinting1.91158287
19MP0010386_abnormal_urinary_bladder1.90925966
20MP0001929_abnormal_gametogenesis1.88687506
21MP0001188_hyperpigmentation1.85547899
22MP0002210_abnormal_sex_determination1.82597412
23MP0005645_abnormal_hypothalamus_physiol1.73257784
24MP0002095_abnormal_skin_pigmentation1.71491533
25MP0008932_abnormal_embryonic_tissue1.68356991
26MP0002102_abnormal_ear_morphology1.67864257
27MP0003880_abnormal_central_pattern1.62959319
28MP0003183_abnormal_peptide_metabolism1.61176747
29MP0005174_abnormal_tail_pigmentation1.59347744
30MP0002163_abnormal_gland_morphology1.57836096
31MP0000678_abnormal_parathyroid_gland1.55661782
32MP0003941_abnormal_skin_development1.55651360
33MP0003937_abnormal_limbs/digits/tail_de1.52846751
34MP0006072_abnormal_retinal_apoptosis1.51287316
35MP0003698_abnormal_male_reproductive1.49814477
36MP0000653_abnormal_sex_gland1.48646164
37MP0002233_abnormal_nose_morphology1.47859676
38MP0003786_premature_aging1.47280228
39MP0000631_abnormal_neuroendocrine_gland1.46501731
40MP0001529_abnormal_vocalization1.45880895
41MP0004147_increased_porphyrin_level1.45740369
42MP0003718_maternal_effect1.45692528
43MP0001145_abnormal_male_reproductive1.40585631
44MP0002234_abnormal_pharynx_morphology1.39904844
45MP0003136_yellow_coat_color1.31358572
46MP0001286_abnormal_eye_development1.30101399
47MP0004270_analgesia1.28012853
48MP0000566_synostosis1.27591134
49MP0000516_abnormal_urinary_system1.26914589
50MP0005367_renal/urinary_system_phenotyp1.26914589
51MP0005253_abnormal_eye_physiology1.25602685
52MP0002693_abnormal_pancreas_physiology1.21852151
53MP0000569_abnormal_digit_pigmentation1.21491551
54MP0003122_maternal_imprinting1.20171931
55MP0001119_abnormal_female_reproductive1.19716214
56MP0010030_abnormal_orbit_morphology1.18993516
57MP0001984_abnormal_olfaction1.17860299
58MP0003119_abnormal_digestive_system1.16205888
59MP0000383_abnormal_hair_follicle1.15579918
60MP0002396_abnormal_hematopoietic_system1.14823572
61MP0002638_abnormal_pupillary_reflex1.14510549
62MP0003890_abnormal_embryonic-extraembry1.14059532
63MP0009697_abnormal_copulation1.14007675
64MP0000647_abnormal_sebaceous_gland1.13848988
65MP0003195_calcinosis1.13627268
66MP0006276_abnormal_autonomic_nervous1.12522599
67MP0002751_abnormal_autonomic_nervous1.09884317
68MP0003806_abnormal_nucleotide_metabolis1.09744228
69MP0005389_reproductive_system_phenotype1.09216462
70MP0001905_abnormal_dopamine_level1.07852791
71MP0008995_early_reproductive_senescence1.06181523
72MP0004215_abnormal_myocardial_fiber1.04840355
73MP0002734_abnormal_mechanical_nocicepti1.04553029
74MP0002697_abnormal_eye_size1.04506620
75MP0005248_abnormal_Harderian_gland1.03490245
76MP0002160_abnormal_reproductive_system0.99096585
77MP0001944_abnormal_pancreas_morphology0.98980756
78MP0003567_abnormal_fetal_cardiomyocyte0.98815125
79MP0000350_abnormal_cell_proliferation0.98765458
80MP0005410_abnormal_fertilization0.98697304
81MP0001672_abnormal_embryogenesis/_devel0.98374340
82MP0005380_embryogenesis_phenotype0.98374340
83MP0002161_abnormal_fertility/fecundity0.97842988
84MP0004808_abnormal_hematopoietic_stem0.97740587
85MP0002085_abnormal_embryonic_tissue0.97637643
86MP0005551_abnormal_eye_electrophysiolog0.95835012
87MP0001666_abnormal_nutrient_absorption0.95170558
88MP0005084_abnormal_gallbladder_morpholo0.94150984
89MP0003635_abnormal_synaptic_transmissio0.93811372
90MP0000490_abnormal_crypts_of0.93740246
91MP0002938_white_spotting0.93719061
92MP0003879_abnormal_hair_cell0.93218842
93MP0005391_vision/eye_phenotype0.92103502
94MP0001177_atelectasis0.91805102
95MP0000313_abnormal_cell_death0.91457420
96MP0000372_irregular_coat_pigmentation0.91159602
97MP0010307_abnormal_tumor_latency0.89525892
98MP0002063_abnormal_learning/memory/cond0.89136686
99MP0001764_abnormal_homeostasis0.88540629
100MP0001919_abnormal_reproductive_system0.88468950
101MP0002572_abnormal_emotion/affect_behav0.88286346
102MP0005395_other_phenotype0.87946761
103MP0001485_abnormal_pinna_reflex0.87909712
104MP0002282_abnormal_trachea_morphology0.87457822
105MP0009703_decreased_birth_body0.87341811
106MP0003943_abnormal_hepatobiliary_system0.86563807
107MP0006035_abnormal_mitochondrial_morpho0.86004872
108MP0003186_abnormal_redox_activity0.85819828
109MP0003861_abnormal_nervous_system0.84967328
110MP0008789_abnormal_olfactory_epithelium0.84900879
111MP0003755_abnormal_palate_morphology0.84209546
112MP0002088_abnormal_embryonic_growth/wei0.83886301
113MP0001186_pigmentation_phenotype0.83489729
114MP0003984_embryonic_growth_retardation0.83318734
115MP0005075_abnormal_melanosome_morpholog0.82565102
116MP0002653_abnormal_ependyma_morphology0.81707076
117MP0001968_abnormal_touch/_nociception0.81294989
118MP0005499_abnormal_olfactory_system0.80681860
119MP0005394_taste/olfaction_phenotype0.80681860
120MP0002837_dystrophic_cardiac_calcinosis0.79263330
121MP0009745_abnormal_behavioral_response0.79095670
122MP0010678_abnormal_skin_adnexa0.78865596
123MP0004197_abnormal_fetal_growth/weight/0.77383960
124MP0003935_abnormal_craniofacial_develop0.77014014
125MP0003385_abnormal_body_wall0.76796090
126MP0003699_abnormal_female_reproductive0.76783111
127MP0001697_abnormal_embryo_size0.76611737
128MP0004264_abnormal_extraembryonic_tissu0.75942068
129MP0002736_abnormal_nociception_after0.75266759
130MP0001346_abnormal_lacrimal_gland0.74557969
131MP0002909_abnormal_adrenal_gland0.73968449
132MP0000427_abnormal_hair_cycle0.73544386
133MP0001486_abnormal_startle_reflex0.73432436
134MP0003283_abnormal_digestive_organ0.73152769
135MP0000681_abnormal_thyroid_gland0.73145914
136MP0006036_abnormal_mitochondrial_physio0.72927982
137MP0005423_abnormal_somatic_nervous0.72451782
138MP0002735_abnormal_chemical_nociception0.72181835
139MP0001730_embryonic_growth_arrest0.72157170
140MP0002557_abnormal_social/conspecific_i0.70576983
141MP0002177_abnormal_outer_ear0.69691756
142MP0002067_abnormal_sensory_capabilities0.67359343
143MP0002876_abnormal_thyroid_physiology0.66949939
144MP0004859_abnormal_synaptic_plasticity0.66583444
145MP0002272_abnormal_nervous_system0.65672906
146MP0004133_heterotaxia0.65351256
147MP0002184_abnormal_innervation0.65282885
148MP0005310_abnormal_salivary_gland0.64742035
149MP0002084_abnormal_developmental_patter0.64060683
150MP0004043_abnormal_pH_regulation0.62752880
151MP0004924_abnormal_behavior0.62571468

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.01398854
2Pancreatic fibrosis (HP:0100732)3.72070638
3Volvulus (HP:0002580)3.35905798
4Chromsome breakage (HP:0040012)3.34271199
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.33810618
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.29861089
7Abnormality of the heme biosynthetic pathway (HP:0010472)3.05251000
8Medial flaring of the eyebrow (HP:0010747)3.04435906
9Pancreatic cysts (HP:0001737)3.03472383
10Dynein arm defect of respiratory motile cilia (HP:0012255)2.95578015
11Absent/shortened dynein arms (HP:0200106)2.95578015
12Abnormal lung lobation (HP:0002101)2.95330578
13True hermaphroditism (HP:0010459)2.95159656
14Molar tooth sign on MRI (HP:0002419)2.89417653
15Abnormality of midbrain morphology (HP:0002418)2.89417653
16Aplasia/Hypoplasia of the uvula (HP:0010293)2.85251906
17Intestinal atresia (HP:0011100)2.84322997
18Nephronophthisis (HP:0000090)2.78456561
19Myelodysplasia (HP:0002863)2.77098598
20Abnormality of chromosome stability (HP:0003220)2.76145774
21Gait imbalance (HP:0002141)2.75099620
22Congenital primary aphakia (HP:0007707)2.74898301
23Abnormality of the preputium (HP:0100587)2.71540673
24Nephrogenic diabetes insipidus (HP:0009806)2.70234475
25Abnormal respiratory motile cilium physiology (HP:0012261)2.69804610
26Meckel diverticulum (HP:0002245)2.61238506
27Rhabdomyosarcoma (HP:0002859)2.59247945
28Abnormal respiratory epithelium morphology (HP:0012253)2.56398432
29Abnormal respiratory motile cilium morphology (HP:0005938)2.56398432
30Patellar aplasia (HP:0006443)2.56360970
31Abnormality of the ileum (HP:0001549)2.53190572
32Hyperglycinemia (HP:0002154)2.52823123
33Poor coordination (HP:0002370)2.48927082
34Papillary thyroid carcinoma (HP:0002895)2.40669349
35Hypothermia (HP:0002045)2.40397198
36Abnormal ciliary motility (HP:0012262)2.40355011
37Acute encephalopathy (HP:0006846)2.39668896
38Septo-optic dysplasia (HP:0100842)2.37321785
39Acute lymphatic leukemia (HP:0006721)2.35666551
40Rhinitis (HP:0012384)2.31472451
41Occipital encephalocele (HP:0002085)2.31383447
42Abnormality of the renal medulla (HP:0100957)2.30873245
43Aplasia/Hypoplasia of the patella (HP:0006498)2.30421513
44Type I transferrin isoform profile (HP:0003642)2.30391861
45Vaginal atresia (HP:0000148)2.29785168
46Medulloblastoma (HP:0002885)2.26710020
47Nephroblastoma (Wilms tumor) (HP:0002667)2.26313285
48Aplastic anemia (HP:0001915)2.25259594
49Small intestinal stenosis (HP:0012848)2.24117901
50Duodenal stenosis (HP:0100867)2.24117901
51Breast hypoplasia (HP:0003187)2.22320657
52Acute necrotizing encephalopathy (HP:0006965)2.22257078
53Severe visual impairment (HP:0001141)2.21807448
54Stenosis of the external auditory canal (HP:0000402)2.20279158
55Protruding tongue (HP:0010808)2.19188934
56Chronic hepatic failure (HP:0100626)2.14964613
57Bifid tongue (HP:0010297)2.14898098
58Type 2 muscle fiber atrophy (HP:0003554)2.13755371
59Methylmalonic acidemia (HP:0002912)2.13168023
60Abnormality of the labia minora (HP:0012880)2.12561294
61Sloping forehead (HP:0000340)2.11989143
62Bile duct proliferation (HP:0001408)2.11737104
63Abnormal biliary tract physiology (HP:0012439)2.11737104
64Cystic liver disease (HP:0006706)2.11162381
65Triphalangeal thumb (HP:0001199)2.10375756
66Chronic bronchitis (HP:0004469)2.08990791
67Embryonal renal neoplasm (HP:0011794)2.08940025
68Cortical dysplasia (HP:0002539)2.08876196
69Aplasia/Hypoplasia of the tongue (HP:0010295)2.05014227
70Increased hepatocellular lipid droplets (HP:0006565)2.04054436
71Abnormal hair whorl (HP:0010721)2.02818578
72Median cleft lip (HP:0000161)2.02700161
73Bone marrow hypocellularity (HP:0005528)2.01709497
74Colon cancer (HP:0003003)2.01571833
75Cerebellar dysplasia (HP:0007033)2.01324902
76Aganglionic megacolon (HP:0002251)1.98605643
77Abnormality of methionine metabolism (HP:0010901)1.97845021
78Abnormality of the carotid arteries (HP:0005344)1.97492783
79Abnormality of aspartate family amino acid metabolism (HP:0010899)1.96433800
80Progressive macrocephaly (HP:0004481)1.94520252
81Glioma (HP:0009733)1.93965268
82Agnosia (HP:0010524)1.93108202
83Hypochromic microcytic anemia (HP:0004840)1.91448179
84Anophthalmia (HP:0000528)1.91211699
85Reduced antithrombin III activity (HP:0001976)1.90739596
86Abnormality of serum amino acid levels (HP:0003112)1.90485861
87Clubbing of toes (HP:0100760)1.90372909
8811 pairs of ribs (HP:0000878)1.89337919
89Hyperglycinuria (HP:0003108)1.88170691
90Aplasia/Hypoplasia of the sternum (HP:0006714)1.87864451
91Oligodactyly (HP:0012165)1.87608392
92Postaxial foot polydactyly (HP:0001830)1.87226145
93Gastrointestinal atresia (HP:0002589)1.86965035
94Degeneration of anterior horn cells (HP:0002398)1.86726113
95Abnormality of the anterior horn cell (HP:0006802)1.86726113
96Oligohydramnios (HP:0001562)1.86654399
97Muscle fiber atrophy (HP:0100295)1.86556878
98Febrile seizures (HP:0002373)1.85422770
99Abnormality of the duodenum (HP:0002246)1.85380147
100Abnormal mitochondria in muscle tissue (HP:0008316)1.84255517
101Cerebral edema (HP:0002181)1.84049147
102Absent septum pellucidum (HP:0001331)1.82848593
103Focal motor seizures (HP:0011153)1.82700847
104Aqueductal stenosis (HP:0002410)1.81289739
105Limb hypertonia (HP:0002509)1.81053156
106Absent radius (HP:0003974)1.80593623
107Neoplasm of striated muscle (HP:0009728)1.80524566
108Dandy-Walker malformation (HP:0001305)1.78278374
109Ependymoma (HP:0002888)1.77156932
110Hypoplasia of the fovea (HP:0007750)1.76157965
111Aplasia/Hypoplasia of the fovea (HP:0008060)1.76157965
112Genital tract atresia (HP:0001827)1.76110784
113Tubulointerstitial nephritis (HP:0001970)1.75518256
114Preaxial hand polydactyly (HP:0001177)1.75012485
115Abnormality of DNA repair (HP:0003254)1.74968198
116Retinal dysplasia (HP:0007973)1.74915493
117Optic nerve hypoplasia (HP:0000609)1.74644794
118Postaxial hand polydactyly (HP:0001162)1.74179015
119Aplasia/Hypoplasia of the tibia (HP:0005772)1.73958146
120Abnormal protein glycosylation (HP:0012346)1.73558700
121Abnormal glycosylation (HP:0012345)1.73558700
122Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.73558700
123Abnormal protein N-linked glycosylation (HP:0012347)1.73558700
124Short tibia (HP:0005736)1.73046653
125Hypoplastic pelvis (HP:0008839)1.72068215
126Abnormality of the renal collecting system (HP:0004742)1.71229490
127Abnormal spermatogenesis (HP:0008669)1.71146987
128Thyroid carcinoma (HP:0002890)1.70995814
129Acute myeloid leukemia (HP:0004808)1.69552039
130Supernumerary spleens (HP:0009799)1.69078485
131Abnormality of glycine metabolism (HP:0010895)1.68298070
132Abnormality of serine family amino acid metabolism (HP:0010894)1.68298070
133Aplasia/Hypoplasia of the sacrum (HP:0008517)1.67672111
134Aplasia involving forearm bones (HP:0009822)1.67600755
135Absent forearm bone (HP:0003953)1.67600755
136Anencephaly (HP:0002323)1.67559835
137Microvesicular hepatic steatosis (HP:0001414)1.67442705
138Increased CSF lactate (HP:0002490)1.66402970
139Multicystic kidney dysplasia (HP:0000003)1.65809817
140Reticulocytopenia (HP:0001896)1.65756631
141Abnormal number of erythroid precursors (HP:0012131)1.65738054
142Type II lissencephaly (HP:0007260)1.65613710
143Abnormality of the septum pellucidum (HP:0007375)1.65303273
144Oligodactyly (hands) (HP:0001180)1.64804370
145Mitochondrial inheritance (HP:0001427)1.63753097
146Exertional dyspnea (HP:0002875)1.63739405
147Lipid accumulation in hepatocytes (HP:0006561)1.62663754
148Hypoplastic female external genitalia (HP:0012815)1.62645963
149Bronchiectasis (HP:0002110)1.62551881
150Abnormality of the parathyroid morphology (HP:0011766)1.61876866

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B3.42876379
2PBK3.26072582
3PLK43.01354722
4BUB12.71938383
5SRPK12.68725247
6CDC72.58653843
7VRK12.56438967
8WEE12.48365441
9TRIM282.39983100
10MUSK2.39648174
11STK162.37403815
12BRSK22.36952053
13PNCK2.31127329
14CCNB12.29658229
15CASK2.26573797
16MAP2K72.19835357
17MKNK22.08771145
18MST42.04767830
19MKNK11.91171734
20PASK1.87628232
21MAPK131.85749739
22BRAF1.78193760
23SIK31.73046400
24MAP3K121.72799087
25MAP3K41.70684622
26NTRK31.65308389
27PLK11.61896617
28PLK31.61860952
29NEK21.61682308
30TNIK1.50730765
31DAPK11.50392987
32ERBB41.47746754
33CDK81.42587207
34BRSK11.38307029
35TTK1.37580345
36MAP3K61.37030048
37DYRK31.36653403
38BRD41.35903208
39AKT31.32445361
40EIF2AK11.32336266
41ATR1.31204253
42FRK1.30659291
43VRK21.29949114
44TAOK31.25388829
45WNK31.25231140
46EIF2AK31.23896013
47TEC1.22847746
48PDK21.22437743
49NLK1.21368405
50AURKB1.18520269
51CHEK21.17525873
52BMPR1B1.16958349
53STK38L1.15415759
54ERBB31.13412126
55INSRR1.12444748
56MAP4K21.12048872
57STK31.09166485
58DYRK21.06656524
59CDK31.02957832
60ZAK1.02403942
61STK391.02025815
62AURKA0.90587210
63TSSK60.90410189
64BMPR20.89004740
65SGK20.87078936
66MINK10.82640470
67MAPKAPK30.81548303
68BCR0.80848010
69PLK20.79184645
70OBSCN0.79147107
71BCKDK0.79005077
72GRK10.78644824
73PINK10.77899402
74ATM0.76794917
75CSNK1G10.76266234
76CDK70.72447789
77CHEK10.71686866
78TLK10.69207891
79PDK30.68030938
80PDK40.68030938
81MARK10.67620728
82EIF2AK20.67431237
83PRKD30.65696512
84UHMK10.64457057
85FGFR20.62166649
86YES10.61496331
87TAF10.61350747
88LATS10.59959464
89IRAK30.59653430
90NEK60.58600024
91ADRBK20.58554650
92RAF10.57041319
93MET0.56726276
94NME10.56128645
95ARAF0.55933644
96EPHA40.54926142
97CDK20.54451254
98RPS6KB10.53534124
99CDK10.52851584
100STK40.52729548
101CDK120.51145646
102CAMKK20.50818958
103OXSR10.48877039
104NUAK10.48871552
105FLT30.48699867
106PRKCG0.47381972
107PRPF4B0.47091876
108FGFR10.47027204
109CSNK2A10.44197401
110TGFBR10.43356190
111DAPK20.43098695
112CSNK1G20.42306275
113CSNK1E0.41574388
114MAPK150.41438311
115TXK0.39757329
116LMTK20.39339987
117RPS6KB20.38653640
118NEK10.38243417
119TAOK20.36269457
120PRKCE0.36225558
121HIPK20.35315091
122MAPKAPK50.33290094
123CSNK1G30.32171295
124DYRK1A0.31548486
125PRKCI0.31228586
126MAPK140.31118806
127NTRK20.30671057
128CSNK2A20.30590825
129CDK190.30518646
130MELK0.29997830
131CSNK1A1L0.29530019
132RPS6KA50.29197468
133PRKACB0.27573423
134PRKDC0.26822137

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.70556165
2DNA replication_Homo sapiens_hsa030303.36067000
3RNA polymerase_Homo sapiens_hsa030203.00252991
4Protein export_Homo sapiens_hsa030602.99317625
5Fanconi anemia pathway_Homo sapiens_hsa034602.93469865
6Homologous recombination_Homo sapiens_hsa034402.80417805
7Basal transcription factors_Homo sapiens_hsa030222.70814982
8Cell cycle_Homo sapiens_hsa041102.70703799
9Propanoate metabolism_Homo sapiens_hsa006402.56955255
10Spliceosome_Homo sapiens_hsa030402.55250587
11RNA degradation_Homo sapiens_hsa030182.52109075
12RNA transport_Homo sapiens_hsa030132.33529452
13Nucleotide excision repair_Homo sapiens_hsa034202.33316471
14Maturity onset diabetes of the young_Homo sapiens_hsa049502.29536306
15Base excision repair_Homo sapiens_hsa034102.29112179
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.23913682
17Proteasome_Homo sapiens_hsa030502.23635621
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13609907
19Non-homologous end-joining_Homo sapiens_hsa034502.09657262
20Pyrimidine metabolism_Homo sapiens_hsa002402.05300607
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.04874582
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.79609208
23Butanoate metabolism_Homo sapiens_hsa006501.76406914
24Ribosome_Homo sapiens_hsa030101.72708461
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.63088902
26mRNA surveillance pathway_Homo sapiens_hsa030151.62637121
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.60156316
28Collecting duct acid secretion_Homo sapiens_hsa049661.51447836
29SNARE interactions in vesicular transport_Homo sapiens_hsa041301.49839523
30Oocyte meiosis_Homo sapiens_hsa041141.47057752
31Purine metabolism_Homo sapiens_hsa002301.41545746
32Pyruvate metabolism_Homo sapiens_hsa006201.40914319
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.40661757
34Nicotine addiction_Homo sapiens_hsa050331.38941531
35Steroid biosynthesis_Homo sapiens_hsa001001.38020728
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.32784868
37Fatty acid elongation_Homo sapiens_hsa000621.25878159
38Selenocompound metabolism_Homo sapiens_hsa004501.25491394
39Synaptic vesicle cycle_Homo sapiens_hsa047211.25128830
40Huntingtons disease_Homo sapiens_hsa050161.25053949
41Primary bile acid biosynthesis_Homo sapiens_hsa001201.20595717
42Alcoholism_Homo sapiens_hsa050341.20144096
43Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.18745699
44Peroxisome_Homo sapiens_hsa041461.18513608
45Oxidative phosphorylation_Homo sapiens_hsa001901.15515268
46Pentose and glucuronate interconversions_Homo sapiens_hsa000401.15268110
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14403299
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.13790254
49Caffeine metabolism_Homo sapiens_hsa002321.10794764
50Amphetamine addiction_Homo sapiens_hsa050311.08700019
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.08559891
52Glutathione metabolism_Homo sapiens_hsa004801.06781364
53p53 signaling pathway_Homo sapiens_hsa041151.05875218
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01726896
55Parkinsons disease_Homo sapiens_hsa050120.99456363
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98138909
57Taste transduction_Homo sapiens_hsa047420.98063756
58Insulin secretion_Homo sapiens_hsa049110.97470101
59Circadian rhythm_Homo sapiens_hsa047100.96517970
60Type I diabetes mellitus_Homo sapiens_hsa049400.96377262
61Retinol metabolism_Homo sapiens_hsa008300.95650965
62Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94811996
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.92895275
64Systemic lupus erythematosus_Homo sapiens_hsa053220.92206051
65beta-Alanine metabolism_Homo sapiens_hsa004100.91648961
66Vibrio cholerae infection_Homo sapiens_hsa051100.90549541
67Epstein-Barr virus infection_Homo sapiens_hsa051690.89767550
68Chemical carcinogenesis_Homo sapiens_hsa052040.88597088
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.85141050
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84991516
71Fatty acid degradation_Homo sapiens_hsa000710.84952621
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.83346305
73Tryptophan metabolism_Homo sapiens_hsa003800.83144361
74One carbon pool by folate_Homo sapiens_hsa006700.81828443
75Regulation of autophagy_Homo sapiens_hsa041400.80353841
76Serotonergic synapse_Homo sapiens_hsa047260.78880711
77Long-term potentiation_Homo sapiens_hsa047200.77532121
78Carbon metabolism_Homo sapiens_hsa012000.77385860
79Fatty acid metabolism_Homo sapiens_hsa012120.76216554
80Dopaminergic synapse_Homo sapiens_hsa047280.75085238
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73725977
82Alzheimers disease_Homo sapiens_hsa050100.73592045
83Circadian entrainment_Homo sapiens_hsa047130.73153831
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72504669
85Herpes simplex infection_Homo sapiens_hsa051680.71363048
86Metabolic pathways_Homo sapiens_hsa011000.69673246
87Basal cell carcinoma_Homo sapiens_hsa052170.69615110
88N-Glycan biosynthesis_Homo sapiens_hsa005100.68514200
89Nitrogen metabolism_Homo sapiens_hsa009100.68019672
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.68017129
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66839127
92Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.65584772
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.65446783
94Cocaine addiction_Homo sapiens_hsa050300.58011353
95Morphine addiction_Homo sapiens_hsa050320.56025812
96Hedgehog signaling pathway_Homo sapiens_hsa043400.53982930
97Cardiac muscle contraction_Homo sapiens_hsa042600.52725883
98Biosynthesis of amino acids_Homo sapiens_hsa012300.52654160
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.52068148
100Tyrosine metabolism_Homo sapiens_hsa003500.51639067
101Colorectal cancer_Homo sapiens_hsa052100.51456795
102Glutamatergic synapse_Homo sapiens_hsa047240.51038980
103Olfactory transduction_Homo sapiens_hsa047400.50418453
104Arginine and proline metabolism_Homo sapiens_hsa003300.50230248
105Viral carcinogenesis_Homo sapiens_hsa052030.50050993
106TGF-beta signaling pathway_Homo sapiens_hsa043500.49683238
107Hippo signaling pathway_Homo sapiens_hsa043900.49308406
108Phenylalanine metabolism_Homo sapiens_hsa003600.48540876
109Sulfur metabolism_Homo sapiens_hsa009200.47061103
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44783318
111Wnt signaling pathway_Homo sapiens_hsa043100.43554131
112Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43281071
113Rheumatoid arthritis_Homo sapiens_hsa053230.43245703
114Fat digestion and absorption_Homo sapiens_hsa049750.42260306
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42188764
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.41876577
117Vitamin B6 metabolism_Homo sapiens_hsa007500.41704436
118Drug metabolism - other enzymes_Homo sapiens_hsa009830.40666325
119Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.40135747
120Starch and sucrose metabolism_Homo sapiens_hsa005000.38461984
121Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37910454
122Linoleic acid metabolism_Homo sapiens_hsa005910.36802288
123Phototransduction_Homo sapiens_hsa047440.36786954
124Vitamin digestion and absorption_Homo sapiens_hsa049770.35396192
125Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.34974202
126GABAergic synapse_Homo sapiens_hsa047270.33751655
127Thyroid cancer_Homo sapiens_hsa052160.32564375
128Glucagon signaling pathway_Homo sapiens_hsa049220.31677946
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30642607
130Calcium signaling pathway_Homo sapiens_hsa040200.30410874
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29448540
132Type II diabetes mellitus_Homo sapiens_hsa049300.29168393
133HTLV-I infection_Homo sapiens_hsa051660.28175712
134Cholinergic synapse_Homo sapiens_hsa047250.28140774
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27414966
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27255091
137Folate biosynthesis_Homo sapiens_hsa007900.27009774
138FoxO signaling pathway_Homo sapiens_hsa040680.26745178
139Endometrial cancer_Homo sapiens_hsa052130.25849188
140Hematopoietic cell lineage_Homo sapiens_hsa046400.24278785
141Prolactin signaling pathway_Homo sapiens_hsa049170.23660912
142Arachidonic acid metabolism_Homo sapiens_hsa005900.20612299
143Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20401354
144Phagosome_Homo sapiens_hsa041450.19404089
145NOD-like receptor signaling pathway_Homo sapiens_hsa046210.19320854
146Other glycan degradation_Homo sapiens_hsa005110.19282669
147Influenza A_Homo sapiens_hsa051640.18577277
148Sphingolipid metabolism_Homo sapiens_hsa006000.18194627
149Long-term depression_Homo sapiens_hsa047300.17522014
150Carbohydrate digestion and absorption_Homo sapiens_hsa049730.17423145
151Phosphatidylinositol signaling system_Homo sapiens_hsa040700.16964319
152Hepatitis B_Homo sapiens_hsa051610.13655295

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