CEP95

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)5.69149839
2piRNA metabolic process (GO:0034587)5.41261566
3mitotic sister chromatid cohesion (GO:0007064)5.12747974
4limb bud formation (GO:0060174)4.69735691
5regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.55641711
6negative regulation of translation, ncRNA-mediated (GO:0040033)4.39442001
7regulation of translation, ncRNA-mediated (GO:0045974)4.39442001
8negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.39442001
9nuclear pore complex assembly (GO:0051292)4.36025547
10fusion of sperm to egg plasma membrane (GO:0007342)4.25915647
11male meiosis (GO:0007140)4.24747879
12motile cilium assembly (GO:0044458)4.14593607
13nuclear pore organization (GO:0006999)4.09059511
14meiotic chromosome segregation (GO:0045132)4.08819774
15multicellular organism reproduction (GO:0032504)4.08552077
16neural tube formation (GO:0001841)4.06153332
17sperm-egg recognition (GO:0035036)4.06145024
18monoubiquitinated protein deubiquitination (GO:0035520)4.02729590
19DNA methylation involved in gamete generation (GO:0043046)4.02350980
20replication fork processing (GO:0031297)3.90340281
21axonemal dynein complex assembly (GO:0070286)3.89131704
22cell-cell recognition (GO:0009988)3.87284930
23binding of sperm to zona pellucida (GO:0007339)3.87106715
24meiotic cell cycle (GO:0051321)3.84910101
25mitotic chromosome condensation (GO:0007076)3.84709041
26DNA double-strand break processing (GO:0000729)3.84675194
27epithelial cilium movement (GO:0003351)3.75872657
28regulation of DNA endoreduplication (GO:0032875)3.75578673
29epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.74667553
30male meiosis I (GO:0007141)3.73910504
31gene silencing by RNA (GO:0031047)3.73785742
32regulation of RNA export from nucleus (GO:0046831)3.71642421
33protein localization to chromosome, centromeric region (GO:0071459)3.67123862
34acrosome assembly (GO:0001675)3.65957484
35negative regulation of histone methylation (GO:0031061)3.60951417
36regulation of histone H3-K9 methylation (GO:0051570)3.59441898
37sister chromatid cohesion (GO:0007062)3.55461049
38histone H3-K4 trimethylation (GO:0080182)3.54702633
39mitotic nuclear envelope disassembly (GO:0007077)3.51912532
40regulation of sister chromatid cohesion (GO:0007063)3.49441347
41cell wall macromolecule catabolic process (GO:0016998)3.49216372
42cell wall macromolecule metabolic process (GO:0044036)3.49216372
43chromosome organization involved in meiosis (GO:0070192)3.46552274
44histone H2A acetylation (GO:0043968)3.45067727
45regulation of meiosis I (GO:0060631)3.44056251
46synaptonemal complex assembly (GO:0007130)3.43664621
47regulation of centriole replication (GO:0046599)3.41608380
48sperm motility (GO:0030317)3.39281090
49response to pheromone (GO:0019236)3.38696710
50synaptonemal complex organization (GO:0070193)3.37400507
51meiotic nuclear division (GO:0007126)3.36969258
52intra-S DNA damage checkpoint (GO:0031573)3.36961823
53kinetochore organization (GO:0051383)3.33304106
54pore complex assembly (GO:0046931)3.30545533
55intraciliary transport (GO:0042073)3.29967584
56negative regulation of DNA-dependent DNA replication (GO:2000104)3.29960381
57cilium movement (GO:0003341)3.29192034
58protein K11-linked deubiquitination (GO:0035871)3.26679954
59regulation of spindle checkpoint (GO:0090231)3.26515716
60DNA replication-independent nucleosome organization (GO:0034724)3.26475222
61DNA replication-independent nucleosome assembly (GO:0006336)3.26475222
62spermatid development (GO:0007286)3.25715018
63histone H3-K9 methylation (GO:0051567)3.25533721
64centriole assembly (GO:0098534)3.25329087
65histone exchange (GO:0043486)3.23885217
66protein localization to kinetochore (GO:0034501)3.23242124
67prenylation (GO:0097354)3.22408268
68protein prenylation (GO:0018342)3.22408268
69nuclear envelope disassembly (GO:0051081)3.19745694
70membrane disassembly (GO:0030397)3.19745694
71regulation of cilium movement (GO:0003352)3.19381923
72histone H3-K9 modification (GO:0061647)3.18414005
73positive regulation of histone methylation (GO:0031062)3.17483406
74synapsis (GO:0007129)3.16834728
75peptidyl-lysine trimethylation (GO:0018023)3.16804788
76microtubule anchoring (GO:0034453)3.16780655
77double-strand break repair via homologous recombination (GO:0000724)3.15776915
78recombinational repair (GO:0000725)3.15093699
79chromatin remodeling at centromere (GO:0031055)3.14755037
80CENP-A containing nucleosome assembly (GO:0034080)3.14330806
81attachment of spindle microtubules to kinetochore (GO:0008608)3.14321253
82microtubule depolymerization (GO:0007019)3.11767377
83centriole replication (GO:0007099)3.11752034
84meiosis I (GO:0007127)3.11579884
85metaphase plate congression (GO:0051310)3.10762021
86regulation of histone H3-K27 methylation (GO:0061085)3.10355083
87sister chromatid segregation (GO:0000819)3.09685730
88protein localization to chromosome (GO:0034502)3.09440790
89positive regulation of histone H3-K4 methylation (GO:0051571)3.09040368
90reproduction (GO:0000003)3.08644188
91mitotic sister chromatid segregation (GO:0000070)3.08402674
92DNA alkylation (GO:0006305)3.02344794
93DNA methylation (GO:0006306)3.02344794
94mitotic metaphase plate congression (GO:0007080)3.01773848
95maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.01475134
96interkinetic nuclear migration (GO:0022027)2.99921099
97gene silencing (GO:0016458)2.99710959
98positive regulation of cell cycle checkpoint (GO:1901978)2.99352357
99regulation of centrosome duplication (GO:0010824)2.97225499
100chromatin assembly or disassembly (GO:0006333)2.96995636
101plasma membrane fusion (GO:0045026)2.96519676
102regulation of DNA damage checkpoint (GO:2000001)2.96156751
103histone H2A monoubiquitination (GO:0035518)2.95894932
104regulation of centrosome cycle (GO:0046605)2.95599631
105regulation of histone methylation (GO:0031060)2.92921560
106DNA packaging (GO:0006323)2.91623498
107meiotic cell cycle process (GO:1903046)2.90536703
108sympathetic nervous system development (GO:0048485)2.89219560
109regulation of cell cycle checkpoint (GO:1901976)2.88387891
110regulation of nucleobase-containing compound transport (GO:0032239)2.86357912
111regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.85592779
112reciprocal DNA recombination (GO:0035825)2.85184534
113reciprocal meiotic recombination (GO:0007131)2.85184534
114nonmotile primary cilium assembly (GO:0035058)2.85144688
115kinetochore assembly (GO:0051382)2.84532306
116regulation of chromosome segregation (GO:0051983)2.84230324
117single fertilization (GO:0007338)2.84211447
118non-recombinational repair (GO:0000726)2.83511112
119double-strand break repair via nonhomologous end joining (GO:0006303)2.83511112
120histone H3-K4 methylation (GO:0051568)2.83380929
121regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.82982719
122regulation of mitotic spindle checkpoint (GO:1903504)2.82982719
123protein localization to cilium (GO:0061512)2.82955810
124histone mRNA catabolic process (GO:0071044)2.81688329
125poly(A)+ mRNA export from nucleus (GO:0016973)2.81415263
126chromosome condensation (GO:0030261)2.81267383
127DNA topological change (GO:0006265)2.80697282
128spindle checkpoint (GO:0031577)2.80324807
129V(D)J recombination (GO:0033151)2.79677949
130positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.79057917
131positive regulation of mitotic sister chromatid separation (GO:1901970)2.79057917
132positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.79057917
133cornea development in camera-type eye (GO:0061303)2.79054980
134nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.77579013
135establishment of protein localization to Golgi (GO:0072600)2.76593701
136somite development (GO:0061053)2.76297539
137cilium organization (GO:0044782)2.75393775
138peptidyl-lysine methylation (GO:0018022)2.74045289
139resolution of meiotic recombination intermediates (GO:0000712)2.73799116
140regulation of telomere maintenance (GO:0032204)2.73254309
141RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.71880488
142cilium assembly (GO:0042384)2.71703638
143behavioral response to ethanol (GO:0048149)2.68589462
144microtubule organizing center organization (GO:0031023)2.67616413
145negative regulation of DNA recombination (GO:0045910)2.67588641
146somatic hypermutation of immunoglobulin genes (GO:0016446)2.66169372
147somatic diversification of immune receptors via somatic mutation (GO:0002566)2.66169372
148centrosome organization (GO:0051297)2.64670429
149keratinocyte development (GO:0003334)2.62552821
150presynaptic membrane assembly (GO:0097105)2.62319135
151cilium morphogenesis (GO:0060271)2.57031978
152negative regulation of transcription regulatory region DNA binding (GO:2000678)2.56818496
153detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.55301932
154regulation of glucokinase activity (GO:0033131)2.53760823
155regulation of hexokinase activity (GO:1903299)2.53760823
156regulation of mRNA splicing, via spliceosome (GO:0048024)2.50509779
157DNA catabolic process, exonucleolytic (GO:0000738)2.49708800
158regulation of helicase activity (GO:0051095)2.49296167
159photoreceptor cell maintenance (GO:0045494)2.48758906
160axoneme assembly (GO:0035082)2.48620268
161mitotic spindle checkpoint (GO:0071174)2.48228505
162histone lysine methylation (GO:0034968)2.44329613
163regulation of male gonad development (GO:2000018)2.43523107
164double-strand break repair (GO:0006302)2.43064345
165protein targeting to Golgi (GO:0000042)2.42483158
166positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.41909596

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.30315746
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.70586850
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.52761377
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.73061186
5ZNF274_21170338_ChIP-Seq_K562_Hela3.21949742
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.11945712
7SALL1_21062744_ChIP-ChIP_HESCs_Human3.08388461
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.88843784
9CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.74633464
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.73596106
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.66011342
12IGF1R_20145208_ChIP-Seq_DFB_Human2.57426188
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.41059350
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.36268272
15VDR_22108803_ChIP-Seq_LS180_Human2.31735775
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30886748
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.27855536
18CIITA_25753668_ChIP-Seq_RAJI_Human2.23575930
19GBX2_23144817_ChIP-Seq_PC3_Human2.19360146
20TAF15_26573619_Chip-Seq_HEK293_Human2.16780673
21E2F1_21310950_ChIP-Seq_MCF-7_Human1.97504905
22BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.95342900
23P300_19829295_ChIP-Seq_ESCs_Human1.95189413
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.91874008
25AR_21909140_ChIP-Seq_LNCAP_Human1.86855449
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.86204167
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85677875
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85572009
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80828701
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.73556556
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.73121354
32CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.71496673
33ER_23166858_ChIP-Seq_MCF-7_Human1.70065080
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.68686094
35EST1_17652178_ChIP-ChIP_JURKAT_Human1.68394163
36MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.66124768
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.64576203
38VDR_23849224_ChIP-Seq_CD4+_Human1.62526960
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.62132916
40MYC_22102868_ChIP-Seq_BL_Human1.60268713
41TP63_19390658_ChIP-ChIP_HaCaT_Human1.59763063
42CBP_20019798_ChIP-Seq_JUKART_Human1.58397089
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.58397089
44EGR1_19374776_ChIP-ChIP_THP-1_Human1.58208208
45MYB_26560356_Chip-Seq_TH1_Human1.56431879
46STAT3_23295773_ChIP-Seq_U87_Human1.55804934
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.53882448
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.53384564
49SMAD4_21799915_ChIP-Seq_A2780_Human1.52357970
50MYC_18555785_ChIP-Seq_MESCs_Mouse1.50920580
51UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.49980636
52* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.49887662
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.48993540
54STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.48543273
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47961979
56TCF4_23295773_ChIP-Seq_U87_Human1.44585025
57MYB_26560356_Chip-Seq_TH2_Human1.42972362
58IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.41843403
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.41532695
60SCL_19346495_ChIP-Seq_HPC-7_Human1.41481678
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41469974
62SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39550952
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.38744160
64IRF1_19129219_ChIP-ChIP_H3396_Human1.37026445
65RUNX_20019798_ChIP-Seq_JUKART_Human1.36441932
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.33654464
67SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.33088298
68GATA1_26923725_Chip-Seq_HPCs_Mouse1.32650724
69ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.32332554
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32230215
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32208909
72BCAT_22108803_ChIP-Seq_LS180_Human1.31775602
73HOXB4_20404135_ChIP-ChIP_EML_Mouse1.31120115
74AR_25329375_ChIP-Seq_VCAP_Human1.31117155
75KDM5A_27292631_Chip-Seq_BREAST_Human1.29764101
76MYC_19030024_ChIP-ChIP_MESCs_Mouse1.28231754
77POU5F1_16153702_ChIP-ChIP_HESCs_Human1.27825400
78RUNX1_26923725_Chip-Seq_HPCs_Mouse1.27708974
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27515374
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27195368
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27036447
82FLI1_27457419_Chip-Seq_LIVER_Mouse1.26866680
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26643046
84FOXP3_21729870_ChIP-Seq_TREG_Human1.26207002
85NELFA_20434984_ChIP-Seq_ESCs_Mouse1.25843223
86TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23803017
87TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.22874585
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22288624
89MYC_18940864_ChIP-ChIP_HL60_Human1.22090845
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.22052573
91EWS_26573619_Chip-Seq_HEK293_Human1.19457200
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.19222554
93TCF4_22108803_ChIP-Seq_LS180_Human1.18341879
94RUNX2_22187159_ChIP-Seq_PCA_Human1.18183589
95ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17629191
96TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17223625
97PCGF2_27294783_Chip-Seq_ESCs_Mouse1.17166391
98NANOG_18555785_Chip-Seq_ESCs_Mouse1.16552391
99KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16098397
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15130174
101THAP11_20581084_ChIP-Seq_MESCs_Mouse1.13968033
102FLI1_21867929_ChIP-Seq_TH2_Mouse1.12720936
103GABP_17652178_ChIP-ChIP_JURKAT_Human1.12347653
104DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10894603
105LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10552332
106ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10499895
107EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10017108
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08746929
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08631397
110KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.08357088
111RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08345318
112ETS1_20019798_ChIP-Seq_JURKAT_Human1.07520434
113EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06032135
114XRN2_22483619_ChIP-Seq_HELA_Human1.05555555
115TP53_22573176_ChIP-Seq_HFKS_Human1.04913413
116E2F1_18555785_Chip-Seq_ESCs_Mouse1.04668631
117CRX_20693478_ChIP-Seq_RETINA_Mouse1.03852661
118SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02709437
119RNF2_27304074_Chip-Seq_NSC_Mouse1.02126803
120* SPI1_23547873_ChIP-Seq_NB4_Human1.01581573
121GATA3_27048872_Chip-Seq_THYMUS_Human1.01562226
122CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00861180
123CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.00162958
124P53_22387025_ChIP-Seq_ESCs_Mouse0.99394494
125SOX2_19829295_ChIP-Seq_ESCs_Human0.98655580
126NANOG_19829295_ChIP-Seq_ESCs_Human0.98655580
127TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98514070
128FOXM1_26456572_ChIP-Seq_MCF-7_Human0.97945882
129FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.97802217
130UTX_26944678_Chip-Seq_JUKART_Human0.97705439
131P300_18555785_Chip-Seq_ESCs_Mouse0.97594944
132SMAD4_21741376_ChIP-Seq_EPCs_Human0.97033738
133NFE2_27457419_Chip-Seq_LIVER_Mouse0.96636639
134SUZ12_18555785_Chip-Seq_ESCs_Mouse0.96307447
135MYC_18358816_ChIP-ChIP_MESCs_Mouse0.95171269
136MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.93217879
137GABP_19822575_ChIP-Seq_HepG2_Human0.92768049
138PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.91741131
139FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90333994
140JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.90262254
141STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.89738991
142SUZ12_27294783_Chip-Seq_NPCs_Mouse0.89543765
143CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88990285
144HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.88894160
145E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88810426
146HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87772896
147SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.87291648
148VDR_21846776_ChIP-Seq_THP-1_Human0.86115074
149RUNX1_22412390_ChIP-Seq_EML_Mouse0.86037659
150TCF7_22412390_ChIP-Seq_EML_Mouse0.86031444
151CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.85880063
152MYC_19079543_ChIP-ChIP_MESCs_Mouse0.85707551
153NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.85258484
154MAF_26560356_Chip-Seq_TH1_Human0.83481526
155HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.83069150
156RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82971531
157EZH2_27294783_Chip-Seq_NPCs_Mouse0.82771886
158MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.82135723
159ELK1_19687146_ChIP-ChIP_HELA_Human0.81937851
160PKCTHETA_26484144_Chip-Seq_BREAST_Human0.79734738
161ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.79440204
162FUS_26573619_Chip-Seq_HEK293_Human0.78268225
163TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76742425
164POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.76742425
165TTF2_22483619_ChIP-Seq_HELA_Human0.76056332

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.45289923
2MP0008057_abnormal_DNA_replication4.36815287
3MP0003693_abnormal_embryo_hatching4.25602613
4MP0008877_abnormal_DNA_methylation4.19075459
5MP0005410_abnormal_fertilization3.48189965
6MP0008058_abnormal_DNA_repair3.38001112
7MP0003077_abnormal_cell_cycle3.19502542
8MP0003111_abnormal_nucleus_morphology2.95253612
9MP0001929_abnormal_gametogenesis2.83853780
10MP0003763_abnormal_thymus_physiology2.56453836
11MP0003787_abnormal_imprinting2.38345344
12MP0002210_abnormal_sex_determination2.38039535
13MP0003698_abnormal_male_reproductive2.37244874
14MP0002396_abnormal_hematopoietic_system2.33939344
15MP0008007_abnormal_cellular_replicative2.30641292
16MP0002653_abnormal_ependyma_morphology2.19770311
17MP0004808_abnormal_hematopoietic_stem2.17363059
18MP0004957_abnormal_blastocyst_morpholog2.13578250
19MP0003121_genomic_imprinting2.08487416
20MP0001145_abnormal_male_reproductive1.92764296
21MP0000372_irregular_coat_pigmentation1.89064383
22MP0000653_abnormal_sex_gland1.85453020
23MP0003880_abnormal_central_pattern1.84127998
24MP0005075_abnormal_melanosome_morpholog1.83718907
25MP0001984_abnormal_olfaction1.81694835
26MP0005551_abnormal_eye_electrophysiolog1.73400193
27MP0000350_abnormal_cell_proliferation1.72447210
28MP0000703_abnormal_thymus_morphology1.67780950
29MP0000516_abnormal_urinary_system1.67667886
30MP0005367_renal/urinary_system_phenotyp1.67667886
31MP0008789_abnormal_olfactory_epithelium1.64049237
32MP0003786_premature_aging1.61240171
33MP0002161_abnormal_fertility/fecundity1.61001036
34MP0008995_early_reproductive_senescence1.60330774
35MP0005253_abnormal_eye_physiology1.59277138
36MP0002638_abnormal_pupillary_reflex1.54269404
37MP0002938_white_spotting1.53119148
38MP0000631_abnormal_neuroendocrine_gland1.50722042
39MP0002398_abnormal_bone_marrow1.49138101
40MP0000015_abnormal_ear_pigmentation1.47545724
41MP0001730_embryonic_growth_arrest1.45445844
42MP0003195_calcinosis1.43584439
43MP0005671_abnormal_response_to1.43514052
44MP0008932_abnormal_embryonic_tissue1.42722424
45MP0002751_abnormal_autonomic_nervous1.40516999
46MP0001293_anophthalmia1.39119843
47MP0003890_abnormal_embryonic-extraembry1.38641478
48MP0005499_abnormal_olfactory_system1.36380528
49MP0005394_taste/olfaction_phenotype1.36380528
50MP0001672_abnormal_embryogenesis/_devel1.33706625
51MP0005380_embryogenesis_phenotype1.33706625
52MP0002095_abnormal_skin_pigmentation1.33512358
53MP0000566_synostosis1.32525697
54MP0006292_abnormal_olfactory_placode1.32190105
55MP0009697_abnormal_copulation1.31772212
56MP0004264_abnormal_extraembryonic_tissu1.31104941
57MP0000313_abnormal_cell_death1.30456181
58MP0005646_abnormal_pituitary_gland1.28314627
59MP0006276_abnormal_autonomic_nervous1.26220848
60MP0000647_abnormal_sebaceous_gland1.25958752
61MP0000569_abnormal_digit_pigmentation1.25014780
62MP0001697_abnormal_embryo_size1.24844497
63MP0003984_embryonic_growth_retardation1.22836423
64MP0003136_yellow_coat_color1.22554519
65MP0001968_abnormal_touch/_nociception1.22436313
66MP0002088_abnormal_embryonic_growth/wei1.20364663
67MP0004043_abnormal_pH_regulation1.20134459
68MP0001119_abnormal_female_reproductive1.19474150
69MP0002019_abnormal_tumor_incidence1.18271250
70MP0002233_abnormal_nose_morphology1.17298345
71MP0001800_abnormal_humoral_immune1.17289933
72MP0005174_abnormal_tail_pigmentation1.15691348
73MP0002085_abnormal_embryonic_tissue1.15510702
74MP0001529_abnormal_vocalization1.13188751
75MP0000778_abnormal_nervous_system1.12940158
76MP0005397_hematopoietic_system_phenotyp1.11702376
77MP0001545_abnormal_hematopoietic_system1.11702376
78MP0003123_paternal_imprinting1.11435635
79MP0000716_abnormal_immune_system1.10781039
80MP0001324_abnormal_eye_pigmentation1.10723197
81MP0002722_abnormal_immune_system1.09860716
82MP0000490_abnormal_crypts_of1.09627516
83MP0000689_abnormal_spleen_morphology1.08956445
84MP0010352_gastrointestinal_tract_polyps1.08876740
85MP0002084_abnormal_developmental_patter1.07283329
86MP0004133_heterotaxia1.06639358
87MP0009703_decreased_birth_body1.04378241
88MP0002429_abnormal_blood_cell1.03829791
89MP0003699_abnormal_female_reproductive1.03551369
90MP0009333_abnormal_splenocyte_physiolog1.03023092
91MP0005423_abnormal_somatic_nervous1.02906914
92MP0004924_abnormal_behavior1.01857649
93MP0005386_behavior/neurological_phenoty1.01857649
94MP0000383_abnormal_hair_follicle1.01054585
95MP0005171_absent_coat_pigmentation1.00644881
96MP0002080_prenatal_lethality0.99995403
97MP0010307_abnormal_tumor_latency0.99951706
98MP0001286_abnormal_eye_development0.99377167
99MP0002132_abnormal_respiratory_system0.98447032
100MP0003119_abnormal_digestive_system0.98148439
101MP0002234_abnormal_pharynx_morphology0.97651846
102MP0003943_abnormal_hepatobiliary_system0.97157604
103MP0002102_abnormal_ear_morphology0.96507876
104MP0001486_abnormal_startle_reflex0.94972265
105MP0002405_respiratory_system_inflammati0.93488009
106MP0003755_abnormal_palate_morphology0.93217473
107MP0001873_stomach_inflammation0.91001920
108MP0002736_abnormal_nociception_after0.90816927
109MP0004197_abnormal_fetal_growth/weight/0.89968570
110MP0003183_abnormal_peptide_metabolism0.88446636
111MP0002822_catalepsy0.87525717
112MP0010678_abnormal_skin_adnexa0.87221016
113MP0005248_abnormal_Harderian_gland0.87072235
114MP0002086_abnormal_extraembryonic_tissu0.87003037
115MP0002282_abnormal_trachea_morphology0.86848171
116MP0002420_abnormal_adaptive_immunity0.86244024
117MP0002735_abnormal_chemical_nociception0.85442712
118MP0008872_abnormal_physiological_respon0.85313593
119MP0003937_abnormal_limbs/digits/tail_de0.84768447
120MP0004147_increased_porphyrin_level0.84467334
121MP0005187_abnormal_penis_morphology0.83913462
122MP0001819_abnormal_immune_cell0.83873571
123MP0003718_maternal_effect0.83775610
124MP0001485_abnormal_pinna_reflex0.83061902
125MP0005195_abnormal_posterior_eye0.82754565
126MP0003861_abnormal_nervous_system0.82243153
127MP0002452_abnormal_antigen_presenting0.81553914
128MP0001915_intracranial_hemorrhage0.81385403
129MP0003935_abnormal_craniofacial_develop0.80140222
130MP0002166_altered_tumor_susceptibility0.79510130
131MP0002723_abnormal_immune_serum0.79244406
132MP0002184_abnormal_innervation0.77948366
133MP0003567_abnormal_fetal_cardiomyocyte0.77293232
134MP0000685_abnormal_immune_system0.76477947
135MP0000427_abnormal_hair_cycle0.76358167
136MP0002092_abnormal_eye_morphology0.76023203
137MP0004381_abnormal_hair_follicle0.74735725
138MP0001835_abnormal_antigen_presentation0.72829589
139MP0002160_abnormal_reproductive_system0.72684417
140MP0002557_abnormal_social/conspecific_i0.71850738
141MP0005389_reproductive_system_phenotype0.71618731
142MP0000371_diluted_coat_color0.71608631
143MP0005409_darkened_coat_color0.70610956
144MP0002752_abnormal_somatic_nervous0.70196193
145MP0005395_other_phenotype0.69988737
146MP0005379_endocrine/exocrine_gland_phen0.69148119
147MP0005391_vision/eye_phenotype0.66431201
148MP0002009_preneoplasia0.66153557
149MP0006072_abnormal_retinal_apoptosis0.65308671
150MP0001661_extended_life_span0.65132236
151MP0001986_abnormal_taste_sensitivity0.65071228
152MP0001851_eye_inflammation0.64593903
153MP0005384_cellular_phenotype0.63559948
154MP0000432_abnormal_head_morphology0.63464201
155MP0005621_abnormal_cell_physiology0.62995860
156MP0002932_abnormal_joint_morphology0.61001846
157MP0003950_abnormal_plasma_membrane0.60463780
158MP0005076_abnormal_cell_differentiation0.57106966

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.89821882
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.90600863
3Absent/shortened dynein arms (HP:0200106)4.90600863
4Volvulus (HP:0002580)4.41600000
5Abnormal respiratory motile cilium physiology (HP:0012261)4.23050430
6Abnormality of the fingertips (HP:0001211)3.86558311
7Abnormal ciliary motility (HP:0012262)3.52135857
8Impulsivity (HP:0100710)3.35734791
9Hyperventilation (HP:0002883)3.32609420
10Pancreatic cysts (HP:0001737)3.24147675
11Rhinitis (HP:0012384)3.21898297
12Nephronophthisis (HP:0000090)3.20512431
13Abnormal respiratory motile cilium morphology (HP:0005938)3.08983162
14Abnormal respiratory epithelium morphology (HP:0012253)3.08983162
15Ectopic kidney (HP:0000086)3.06133403
16Long eyelashes (HP:0000527)2.98277950
17Pancreatic fibrosis (HP:0100732)2.95516510
18Nasal polyposis (HP:0100582)2.87936730
19Bronchiectasis (HP:0002110)2.75831791
20Chromsome breakage (HP:0040012)2.69379835
21Abnormal hair whorl (HP:0010721)2.65606820
22Abnormality of the renal medulla (HP:0100957)2.57023699
23Medial flaring of the eyebrow (HP:0010747)2.51133313
24Neoplasm of the oral cavity (HP:0100649)2.49560430
25Intestinal atresia (HP:0011100)2.49109018
26Prominent nose (HP:0000448)2.48121629
27Chronic bronchitis (HP:0004469)2.45311783
28Abnormality of the columella (HP:0009929)2.42633696
29Bronchitis (HP:0012387)2.42355208
30Supernumerary spleens (HP:0009799)2.42117342
31Recurrent bronchitis (HP:0002837)2.40384159
32Infertility (HP:0000789)2.38242713
33Hepatoblastoma (HP:0002884)2.36468142
34Thyroiditis (HP:0100646)2.35403734
35Recurrent otitis media (HP:0000403)2.32928535
36Abnormality of DNA repair (HP:0003254)2.31690328
37Sloping forehead (HP:0000340)2.30367043
38Congenital primary aphakia (HP:0007707)2.28478434
39Abnormality of chromosome stability (HP:0003220)2.28456363
40Facial hemangioma (HP:0000329)2.25677465
41Cystic liver disease (HP:0006706)2.24969568
42Chromosomal breakage induced by crosslinking agents (HP:0003221)2.24471773
43T lymphocytopenia (HP:0005403)2.23562533
44Gait imbalance (HP:0002141)2.22361637
45Abnormality of midbrain morphology (HP:0002418)2.21874326
46Molar tooth sign on MRI (HP:0002419)2.21874326
47Increased nuchal translucency (HP:0010880)2.21320471
48Long clavicles (HP:0000890)2.19824768
49Recurrent sinusitis (HP:0011108)2.16266416
50Abnormality of the renal cortex (HP:0011035)2.14698853
51Nephrogenic diabetes insipidus (HP:0009806)2.13465013
52Birth length less than 3rd percentile (HP:0003561)2.13257550
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.13001183
54Deviation of the thumb (HP:0009603)2.11729083
55Genital tract atresia (HP:0001827)2.11456195
56Colon cancer (HP:0003003)2.11192334
57Absent speech (HP:0001344)2.10340087
58Patellar aplasia (HP:0006443)2.08919108
59Truncal obesity (HP:0001956)2.08787077
60Depressed nasal tip (HP:0000437)2.08003010
61Panhypogammaglobulinemia (HP:0003139)2.07309459
62Clubbing of toes (HP:0100760)2.06175328
63Small intestinal stenosis (HP:0012848)2.05266683
64Duodenal stenosis (HP:0100867)2.05266683
65Intestinal fistula (HP:0100819)2.05037299
66Hypoplastic iliac wings (HP:0002866)2.04441897
67Abnormality of the nasal mucosa (HP:0000433)2.03866544
68Astigmatism (HP:0000483)2.03252269
69Broad-based gait (HP:0002136)2.03087890
70Narrow forehead (HP:0000341)2.02822726
71Hypoplastic labia majora (HP:0000059)2.02077047
72Small hand (HP:0200055)2.01624093
73Astrocytoma (HP:0009592)1.99792952
74Abnormality of the astrocytes (HP:0100707)1.99792952
75Vaginal atresia (HP:0000148)1.98854500
76B lymphocytopenia (HP:0010976)1.97973968
77Abnormality of B cell number (HP:0010975)1.97973968
78Abnormality of the duodenum (HP:0002246)1.97819747
79Papillary thyroid carcinoma (HP:0002895)1.97508142
80Abnormal biliary tract physiology (HP:0012439)1.96485861
81Bile duct proliferation (HP:0001408)1.96485861
82Poor coordination (HP:0002370)1.95856688
83Postaxial hand polydactyly (HP:0001162)1.95089472
84Tubulointerstitial nephritis (HP:0001970)1.94444143
85Drooling (HP:0002307)1.93838784
86Abnormality of T cell number (HP:0011839)1.93632037
87Midline defect of the nose (HP:0004122)1.92952509
88Cerebral hypomyelination (HP:0006808)1.91637199
89Myelodysplasia (HP:0002863)1.91633507
90Ependymoma (HP:0002888)1.91236600
91Aplasia/Hypoplasia of the tongue (HP:0010295)1.91188605
92Anal stenosis (HP:0002025)1.91022857
93Acute myeloid leukemia (HP:0004808)1.90796015
94Postaxial foot polydactyly (HP:0001830)1.89642014
95Meckel diverticulum (HP:0002245)1.89638567
96Amaurosis fugax (HP:0100576)1.89070678
97Agammaglobulinemia (HP:0004432)1.88978613
98Recurrent viral infections (HP:0004429)1.88560015
99Widely spaced teeth (HP:0000687)1.88522685
100Broad alveolar ridges (HP:0000187)1.86786626
101Optic nerve coloboma (HP:0000588)1.86667771
102Febrile seizures (HP:0002373)1.86494831
103Gonadotropin excess (HP:0000837)1.86333833
104Secondary amenorrhea (HP:0000869)1.85820575
105Neoplasm of the adrenal cortex (HP:0100641)1.85637625
106Premature ovarian failure (HP:0008209)1.83974740
107Proximal placement of thumb (HP:0009623)1.83673178
108Abnormality of incisor morphology (HP:0011063)1.83270140
109Tented upper lip vermilion (HP:0010804)1.83145949
110Cupped ear (HP:0000378)1.82971181
111Aplasia/Hypoplasia of the patella (HP:0006498)1.82711757
112Glioma (HP:0009733)1.82657617
113Abnormality of the ileum (HP:0001549)1.82649757
114Chronic hepatic failure (HP:0100626)1.81206275
115Urethral obstruction (HP:0000796)1.80366231
116Fair hair (HP:0002286)1.80099499
117Nephroblastoma (Wilms tumor) (HP:0002667)1.79871218
118Dandy-Walker malformation (HP:0001305)1.79740285
119Congenital stationary night blindness (HP:0007642)1.79649588
120Premature skin wrinkling (HP:0100678)1.79644714
121Severe combined immunodeficiency (HP:0004430)1.78855105
122Combined immunodeficiency (HP:0005387)1.78840912
123Abnormality of the incisor (HP:0000676)1.78751496
124Gaze-evoked nystagmus (HP:0000640)1.78680364
125Highly arched eyebrow (HP:0002553)1.78418534
126Heterotopia (HP:0002282)1.76935293
127Abnormality of the labia majora (HP:0012881)1.76013719
128Prominent nasal bridge (HP:0000426)1.76011556
129Abnormal spermatogenesis (HP:0008669)1.75959220
130Aqueductal stenosis (HP:0002410)1.74897423
131Hypoproteinemia (HP:0003075)1.74887058
132Abnormality of the metopic suture (HP:0005556)1.74803094
133Abnormality of the preputium (HP:0100587)1.74759330
134Oligodactyly (hands) (HP:0001180)1.74643859
135Bone marrow hypocellularity (HP:0005528)1.73633362
136Attenuation of retinal blood vessels (HP:0007843)1.73611100
137Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.73524800
138Short 4th metacarpal (HP:0010044)1.73524800
139Pendular nystagmus (HP:0012043)1.73384985
140Aplasia/Hypoplasia of the sternum (HP:0006714)1.72911955
141Protruding tongue (HP:0010808)1.72450088
142Preaxial hand polydactyly (HP:0001177)1.72290238
143Inflammation of the large intestine (HP:0002037)1.72169535
144Excessive salivation (HP:0003781)1.71885380
145Selective tooth agenesis (HP:0001592)1.71743907
146Stomach cancer (HP:0012126)1.71600396
147Trigonocephaly (HP:0000243)1.71506996
148Abnormality of the labia minora (HP:0012880)1.71322117
149Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.71296042
150Short 1st metacarpal (HP:0010034)1.71296042
151Anencephaly (HP:0002323)1.70397704
152Microtia (HP:0008551)1.70026230
153Low anterior hairline (HP:0000294)1.69479066
154Optic nerve hypoplasia (HP:0000609)1.68960145
155Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.68918016
156Aplasia/Hypoplasia of the earlobes (HP:0009906)1.68323879
157Embryonal renal neoplasm (HP:0011794)1.68248439
158Oculomotor apraxia (HP:0000657)1.68121705
159Gastrointestinal atresia (HP:0002589)1.68013526
160Cortical dysplasia (HP:0002539)1.67947367
161True hermaphroditism (HP:0010459)1.67394705
162IgM deficiency (HP:0002850)1.67370043
163Tubulointerstitial abnormality (HP:0001969)1.67335738
164Congenital hepatic fibrosis (HP:0002612)1.66155405
165Abnormality of the distal phalanx of the thumb (HP:0009617)1.66095937
166Pancytopenia (HP:0001876)1.65291126
167Supernumerary ribs (HP:0005815)1.64320337
168Skull defect (HP:0001362)1.64164837

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK3.98312889
2CDC73.43224661
3MAP4K23.39684419
4CDK123.20802981
5BRD43.09660066
6PDK32.90690012
7PDK42.90690012
8NEK22.75008657
9WNK32.70244855
10CASK2.67392569
11STK102.59354458
12AKT32.52203636
13EIF2AK32.18226304
14PLK42.17130764
15TRIM282.16252115
16TTK1.98497932
17MAP3K131.94803715
18DYRK31.92515448
19MELK1.86850804
20ATR1.85391175
21ACVR1B1.84405114
22MAP3K41.83700063
23LATS11.78964619
24STK31.76080543
25EEF2K1.75597839
26EPHA31.75324936
27MAPK131.74952597
28NLK1.72254775
29STK38L1.63463321
30MAP4K11.62176596
31PINK11.61258828
32ERBB31.54806357
33TLK11.53957219
34SIK31.53542048
35CAMK1D1.52032197
36EIF2AK11.48395518
37CLK11.47635320
38CHEK21.46881003
39CHEK11.40751650
40CAMK1G1.38003075
41BTK1.35042803
42NUAK11.31347920
43ZAK1.31033937
44TGFBR21.30802233
45PDK21.30259331
46ITK1.28957468
47CDK91.28671524
48ATM1.27797276
49MARK11.25729443
50PLK21.25726885
51TXK1.24652060
52ICK1.21636353
53INSRR1.18267021
54TEC1.17667683
55PASK1.16666859
56PAK41.13202898
57PLK11.12469112
58ADRBK21.10410761
59MKNK11.06371021
60STK41.04099994
61BCR1.03916922
62MARK31.00104622
63TAOK30.99469735
64CDK70.97638557
65MARK20.97250619
66CDK40.96575053
67PAK30.95918590
68SRPK10.94415824
69AURKB0.88617618
70PNCK0.87501105
71BRSK20.86737654
72PIM10.85829542
73RPS6KA40.81802195
74TESK10.81598145
75KSR10.80950318
76MAP3K100.80758715
77TNIK0.80448589
78SGK20.79080863
79MKNK20.78327501
80MAP3K60.77821559
81CDK20.76042669
82PRPF4B0.74894555
83JAK30.74620992
84OXSR10.74535135
85CDK30.74383876
86STK240.73963537
87BUB10.73917777
88MAP2K70.73359080
89TSSK60.71527489
90MTOR0.71455265
91VRK10.70411752
92CDK10.68021912
93WEE10.67827881
94GRK10.67646244
95MAP3K140.67470030
96TGFBR10.67317486
97TRPM70.66485246
98CSNK1G10.66279861
99EIF2AK20.66180257
100FGFR10.65842028
101LCK0.64942559
102CSNK1A1L0.64166528
103CCNB10.63958600
104PRKCQ0.63366774
105PRKCE0.62628627
106WNK10.62507654
107TAF10.62115095
108EPHA40.60267970
109CHUK0.59732617
110DYRK1A0.59466066
111CSNK1G20.59224598
112IRAK10.59043979
113PRKDC0.58863483
114BMPR1B0.58129031
115IRAK40.57829600
116STK390.57596865
117CSNK1D0.56877580
118PIK3CA0.56082141
119PBK0.54633429
120STK160.54026804
121SIK20.54025954
122PRKAA20.53724156
123BRSK10.52592300
124MST40.51523691
125NEK60.51342499
126MOS0.50975829
127FGFR20.49410208
128WNK40.48766217
129CSNK1G30.48556394
130NME10.47964027
131ZAP700.46877411
132GSK3B0.45940603
133MAPKAPK50.45740578
134CDK80.44968414
135MAPK100.44633230
136LYN0.44381573
137STK110.44148385
138CDK60.43919606
139MAPK140.43708706
140DYRK20.43600928
141CSNK1E0.43173230
142MAP3K80.41914070
143RPS6KA50.41337079
144RPS6KB20.40177148
145MAPK150.39027667
146PLK30.38065707
147TYK20.37900166
148YES10.37468815
149FER0.35775653
150PRKAA10.34679029
151NTRK30.34471555
152PTK2B0.32349850
153PRKCG0.32124950
154SGK2230.31979112

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002326.40434839
2Non-homologous end-joining_Homo sapiens_hsa034503.54480156
3Fanconi anemia pathway_Homo sapiens_hsa034602.84818013
4Cell cycle_Homo sapiens_hsa041102.83854733
5Mismatch repair_Homo sapiens_hsa034302.72539172
6mRNA surveillance pathway_Homo sapiens_hsa030152.61880434
7Basal transcription factors_Homo sapiens_hsa030222.60873713
8RNA transport_Homo sapiens_hsa030132.58006295
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.57883678
10RNA degradation_Homo sapiens_hsa030182.52706383
11DNA replication_Homo sapiens_hsa030302.47330926
12Spliceosome_Homo sapiens_hsa030402.39534714
13Protein export_Homo sapiens_hsa030602.36662994
14Propanoate metabolism_Homo sapiens_hsa006402.33296285
15Primary immunodeficiency_Homo sapiens_hsa053402.31131583
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.27979509
17Base excision repair_Homo sapiens_hsa034102.21951269
18Homologous recombination_Homo sapiens_hsa034402.15733575
19Butanoate metabolism_Homo sapiens_hsa006501.91387479
20Phototransduction_Homo sapiens_hsa047441.72218414
21Nucleotide excision repair_Homo sapiens_hsa034201.70913186
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.70094893
23Herpes simplex infection_Homo sapiens_hsa051681.53752385
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.47546481
25Antigen processing and presentation_Homo sapiens_hsa046121.45225129
26Vitamin B6 metabolism_Homo sapiens_hsa007501.40997282
27Nicotine addiction_Homo sapiens_hsa050331.33140973
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.29733028
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28314502
30Notch signaling pathway_Homo sapiens_hsa043301.27051947
31Nitrogen metabolism_Homo sapiens_hsa009101.24232849
32Lysine degradation_Homo sapiens_hsa003101.23124692
33Transcriptional misregulation in cancer_Homo sapiens_hsa052021.22794393
34T cell receptor signaling pathway_Homo sapiens_hsa046601.20469829
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20300260
36Taste transduction_Homo sapiens_hsa047421.17925013
37Oocyte meiosis_Homo sapiens_hsa041141.17873005
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.16769197
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.15349460
40NF-kappa B signaling pathway_Homo sapiens_hsa040641.14204748
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11787165
42Olfactory transduction_Homo sapiens_hsa047401.10467783
43Viral carcinogenesis_Homo sapiens_hsa052031.09467915
44HTLV-I infection_Homo sapiens_hsa051661.09130827
45p53 signaling pathway_Homo sapiens_hsa041151.08498840
46Hedgehog signaling pathway_Homo sapiens_hsa043401.07958339
47RNA polymerase_Homo sapiens_hsa030201.06755868
48B cell receptor signaling pathway_Homo sapiens_hsa046621.04719843
49Pyrimidine metabolism_Homo sapiens_hsa002401.04356155
50Circadian rhythm_Homo sapiens_hsa047101.04036091
51Systemic lupus erythematosus_Homo sapiens_hsa053221.01431442
52Measles_Homo sapiens_hsa051621.00291573
53Epstein-Barr virus infection_Homo sapiens_hsa051690.98558865
54Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96233238
55Hematopoietic cell lineage_Homo sapiens_hsa046400.95555780
56Sulfur relay system_Homo sapiens_hsa041220.91550932
57One carbon pool by folate_Homo sapiens_hsa006700.90708944
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88774788
59Pancreatic cancer_Homo sapiens_hsa052120.87295921
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85015178
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.84767773
62Linoleic acid metabolism_Homo sapiens_hsa005910.83404803
63Retinol metabolism_Homo sapiens_hsa008300.82852814
64Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.82759499
65Maturity onset diabetes of the young_Homo sapiens_hsa049500.81662906
66MicroRNAs in cancer_Homo sapiens_hsa052060.77164537
67Small cell lung cancer_Homo sapiens_hsa052220.75607900
68Proteasome_Homo sapiens_hsa030500.75234738
69Jak-STAT signaling pathway_Homo sapiens_hsa046300.74896147
70Tryptophan metabolism_Homo sapiens_hsa003800.74426998
71Chemical carcinogenesis_Homo sapiens_hsa052040.73438233
72Ether lipid metabolism_Homo sapiens_hsa005650.70818601
73Steroid biosynthesis_Homo sapiens_hsa001000.69993664
74Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68508168
75Chronic myeloid leukemia_Homo sapiens_hsa052200.68422296
76Colorectal cancer_Homo sapiens_hsa052100.67873738
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.67603944
78Hepatitis B_Homo sapiens_hsa051610.67345904
79TGF-beta signaling pathway_Homo sapiens_hsa043500.67294878
80Purine metabolism_Homo sapiens_hsa002300.65026924
81ABC transporters_Homo sapiens_hsa020100.63881054
82Selenocompound metabolism_Homo sapiens_hsa004500.63492186
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62204766
84Peroxisome_Homo sapiens_hsa041460.56163445
85Cocaine addiction_Homo sapiens_hsa050300.55366612
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.54498515
87Basal cell carcinoma_Homo sapiens_hsa052170.54483671
88Thyroid cancer_Homo sapiens_hsa052160.54453476
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.53545606
90Glucagon signaling pathway_Homo sapiens_hsa049220.53191545
91Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52110690
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52109586
93Wnt signaling pathway_Homo sapiens_hsa043100.52021109
94N-Glycan biosynthesis_Homo sapiens_hsa005100.51729314
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.50885420
96FoxO signaling pathway_Homo sapiens_hsa040680.50486887
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50095843
98Influenza A_Homo sapiens_hsa051640.49484659
99Adherens junction_Homo sapiens_hsa045200.48773886
100Acute myeloid leukemia_Homo sapiens_hsa052210.48673663
101Inositol phosphate metabolism_Homo sapiens_hsa005620.47482621
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46876427
103Osteoclast differentiation_Homo sapiens_hsa043800.46622975
104Morphine addiction_Homo sapiens_hsa050320.46283642
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44657307
106Prostate cancer_Homo sapiens_hsa052150.44598935
107Pathways in cancer_Homo sapiens_hsa052000.42882720
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42324078
109Serotonergic synapse_Homo sapiens_hsa047260.41815433
110Glutamatergic synapse_Homo sapiens_hsa047240.41345291
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41118441
112Long-term depression_Homo sapiens_hsa047300.40799043
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40588005
114Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37410546
115Circadian entrainment_Homo sapiens_hsa047130.37334897
116Glycerolipid metabolism_Homo sapiens_hsa005610.37324705
117Dopaminergic synapse_Homo sapiens_hsa047280.37144237
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.35285627
119Hippo signaling pathway_Homo sapiens_hsa043900.34511248
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34141211
121Dorso-ventral axis formation_Homo sapiens_hsa043200.34055684
122Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33328400
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32645345
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31713555
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.31521990
126Regulation of autophagy_Homo sapiens_hsa041400.30034617
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29603490
128mTOR signaling pathway_Homo sapiens_hsa041500.28823509
129Alcoholism_Homo sapiens_hsa050340.28448788
130Metabolic pathways_Homo sapiens_hsa011000.28348000
131Fatty acid degradation_Homo sapiens_hsa000710.28276338
132Fatty acid metabolism_Homo sapiens_hsa012120.26895999
133Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26580795
134Primary bile acid biosynthesis_Homo sapiens_hsa001200.25827797
135Toxoplasmosis_Homo sapiens_hsa051450.25474446
136Choline metabolism in cancer_Homo sapiens_hsa052310.25429597
137Insulin secretion_Homo sapiens_hsa049110.25049900
138Arachidonic acid metabolism_Homo sapiens_hsa005900.24721697
139Drug metabolism - other enzymes_Homo sapiens_hsa009830.23439916
140Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.22718660
141NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22165796
142Chemokine signaling pathway_Homo sapiens_hsa040620.21328448
143Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.19410898
144Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.18757825
145Graft-versus-host disease_Homo sapiens_hsa053320.18634196
146Apoptosis_Homo sapiens_hsa042100.18504702
147Non-small cell lung cancer_Homo sapiens_hsa052230.18488466
148Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.18329396
149AMPK signaling pathway_Homo sapiens_hsa041520.17443808
150Pyruvate metabolism_Homo sapiens_hsa006200.16499932
151Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.15822020

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