CFAP100

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.81947011
2epithelial cilium movement (GO:0003351)9.65718174
3axoneme assembly (GO:0035082)8.95047412
4ventricular system development (GO:0021591)8.51192046
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.87429037
6GTP biosynthetic process (GO:0006183)7.14738348
7primary alcohol catabolic process (GO:0034310)6.69003739
8motile cilium assembly (GO:0044458)6.52056364
9left/right axis specification (GO:0070986)6.30604943
10UTP biosynthetic process (GO:0006228)6.20247503
11vitamin transmembrane transport (GO:0035461)6.13024748
12nucleoside diphosphate phosphorylation (GO:0006165)5.90331785
13UTP metabolic process (GO:0046051)5.79633717
14ethanol metabolic process (GO:0006067)5.78667921
15diterpenoid biosynthetic process (GO:0016102)5.41636730
16centriole assembly (GO:0098534)5.37790596
17cilium organization (GO:0044782)4.60980923
18lung epithelium development (GO:0060428)4.60423208
19pyrimidine-containing compound transmembrane transport (GO:0072531)4.55722302
20response to xenobiotic stimulus (GO:0009410)4.55434251
21intraciliary transport (GO:0042073)4.55227495
22tolerance induction (GO:0002507)4.53988842
23sperm motility (GO:0030317)4.49082106
24CTP biosynthetic process (GO:0006241)4.45865316
25CTP metabolic process (GO:0046036)4.45865316
26establishment of apical/basal cell polarity (GO:0035089)4.44757886
27glomerular epithelial cell development (GO:0072310)4.42389566
28guanosine-containing compound biosynthetic process (GO:1901070)4.40624713
29regulation of interleukin-5 production (GO:0032674)4.39138287
30ethanol oxidation (GO:0006069)4.37826992
31cilium assembly (GO:0042384)4.34341296
32negative regulation of T cell differentiation in thymus (GO:0033085)4.31210175
33microtubule depolymerization (GO:0007019)4.26582006
34microtubule bundle formation (GO:0001578)4.19862329
35microtubule polymerization or depolymerization (GO:0031109)4.11314304
36negative regulation of immunoglobulin mediated immune response (GO:0002890)4.10849781
37negative regulation of B cell mediated immunity (GO:0002713)4.10849781
38regulation of interleukin-13 production (GO:0032656)3.98443357
39cilium morphogenesis (GO:0060271)3.97951211
40regulation of cilium movement (GO:0003352)3.95373779
41pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.94496899
42left/right pattern formation (GO:0060972)3.94418919
43negative regulation of humoral immune response (GO:0002921)3.93523181
44lateral ventricle development (GO:0021670)3.87293961
45establishment or maintenance of monopolar cell polarity (GO:0061339)3.84755765
46establishment of monopolar cell polarity (GO:0061162)3.84755765
47terpenoid biosynthetic process (GO:0016114)3.78664547
48pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.78145972
49retinoic acid metabolic process (GO:0042573)3.75044610
50negative regulation of inclusion body assembly (GO:0090084)3.73463723
51regulation of germinal center formation (GO:0002634)3.72943671
52negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.72276401
53fusion of sperm to egg plasma membrane (GO:0007342)3.69555330
54cellular component assembly involved in morphogenesis (GO:0010927)3.68545322
55acrosome reaction (GO:0007340)3.68403516
56establishment of tissue polarity (GO:0007164)3.67234194
57establishment of planar polarity (GO:0001736)3.67234194
58positive regulation of tolerance induction (GO:0002645)3.64437525
59cytoplasmic microtubule organization (GO:0031122)3.56920532
60protein localization to cilium (GO:0061512)3.56860804
61one-carbon compound transport (GO:0019755)3.48521881
62microtubule-based movement (GO:0007018)3.45718323
63central nervous system myelination (GO:0022010)3.43897156
64axon ensheathment in central nervous system (GO:0032291)3.43897156
65vocalization behavior (GO:0071625)3.41376738
66acrosome assembly (GO:0001675)3.30412383
67pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.28298540
68multicellular organism reproduction (GO:0032504)3.26760236
69spermatid development (GO:0007286)3.25817688
70exogenous drug catabolic process (GO:0042738)3.23594683
71retinal rod cell development (GO:0046548)3.23457631
72negative regulation of astrocyte differentiation (GO:0048712)3.21614517
73nucleotide phosphorylation (GO:0046939)3.20819584
74cell wall macromolecule catabolic process (GO:0016998)3.19489813
75cell wall macromolecule metabolic process (GO:0044036)3.19489813
76centriole replication (GO:0007099)3.16940885
77neuron cell-cell adhesion (GO:0007158)3.15861390
78positive regulation of smoothened signaling pathway (GO:0045880)3.14082524
79regulation of pigment cell differentiation (GO:0050932)3.12503568
80cell projection assembly (GO:0030031)3.09661838
81regulation of inclusion body assembly (GO:0090083)3.07159170
82microtubule severing (GO:0051013)3.05301320
83primary alcohol metabolic process (GO:0034308)3.04381077
84determination of left/right symmetry (GO:0007368)3.03503121
85O-glycan processing (GO:0016266)3.03453755
86ionotropic glutamate receptor signaling pathway (GO:0035235)3.01577005
87glutamate receptor signaling pathway (GO:0007215)3.01043147
88sensory perception of smell (GO:0007608)2.98491466
89lateral sprouting from an epithelium (GO:0060601)2.93821937
90single fertilization (GO:0007338)2.93455429
91retinol metabolic process (GO:0042572)2.93004194
92plasma membrane fusion (GO:0045026)2.92744794
93determination of bilateral symmetry (GO:0009855)2.90706513
94pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.89121591
95phosphatidylethanolamine biosynthetic process (GO:0006646)2.87128100
96cerebral cortex neuron differentiation (GO:0021895)2.86739791
97microtubule-based process (GO:0007017)2.85372510
98specification of symmetry (GO:0009799)2.84815385
99phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.82704544
100hydrogen peroxide biosynthetic process (GO:0050665)2.80234137
101smoothened signaling pathway (GO:0007224)2.79365183
102phosphatidylcholine biosynthetic process (GO:0006656)2.78244068
103protein localization to synapse (GO:0035418)2.76985535
104transmission of nerve impulse (GO:0019226)2.76362703
105glutathione derivative biosynthetic process (GO:1901687)2.73849027
106glutathione derivative metabolic process (GO:1901685)2.73849027
107regulation of microtubule depolymerization (GO:0031114)2.72497378
108positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.71589591
109nucleoside diphosphate metabolic process (GO:0009132)2.70570877
110positive regulation of meiosis (GO:0045836)2.70434424
111response to histamine (GO:0034776)2.70038262
112carnitine metabolic process (GO:0009437)2.70017770
113sperm-egg recognition (GO:0035036)2.68844235
114protein polyglutamylation (GO:0018095)2.68498557
115regulation of tolerance induction (GO:0002643)2.67827992
116apical protein localization (GO:0045176)2.64569429
117organelle assembly (GO:0070925)2.64082276
118aldehyde catabolic process (GO:0046185)2.63308920
119protein refolding (GO:0042026)2.63194736
120multicellular organismal water homeostasis (GO:0050891)2.61246347
121presynaptic membrane assembly (GO:0097105)2.61130711
122regulation of astrocyte differentiation (GO:0048710)2.61083811
123phosphatidylethanolamine metabolic process (GO:0046337)2.60458886
124postsynaptic membrane organization (GO:0001941)2.60238088
125heart valve formation (GO:0003188)2.58075559
126positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.57781909
127heart looping (GO:0001947)2.56068406
128regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.54405413
129G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.54114694
130excretion (GO:0007588)2.50352976
131oligodendrocyte differentiation (GO:0048709)2.49968958
132neuron recognition (GO:0008038)2.49777241
133drug catabolic process (GO:0042737)2.49681860
134neuronal action potential propagation (GO:0019227)2.48329333
135regulation of response to osmotic stress (GO:0047484)2.47957076
136positive regulation of meiotic cell cycle (GO:0051446)2.47350676
137reactive oxygen species biosynthetic process (GO:1903409)2.47326825
138fertilization (GO:0009566)2.45633879
139otic vesicle formation (GO:0030916)2.44747492
140regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.44483740
141reproduction (GO:0000003)2.43411937
142brain morphogenesis (GO:0048854)2.41410765
143regulation of microtubule-based movement (GO:0060632)2.40104357
144negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.39631642
145regulation of cilium assembly (GO:1902017)2.39356877
146long-term synaptic potentiation (GO:0060291)2.38984683
147gamma-aminobutyric acid signaling pathway (GO:0007214)2.38726719
148progesterone metabolic process (GO:0042448)2.38123856
149calcium ion-dependent exocytosis (GO:0017156)2.37478598
150L-amino acid import (GO:0043092)2.37152189
151embryonic camera-type eye development (GO:0031076)2.36887102
152cell-cell recognition (GO:0009988)2.36059698
153long-term memory (GO:0007616)2.35256800
154presynaptic membrane organization (GO:0097090)2.34893136
155pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.34785204
156embryonic heart tube morphogenesis (GO:0003143)2.34060709
157regulation of smoothened signaling pathway (GO:0008589)2.33717390
158membrane depolarization during action potential (GO:0086010)2.32224321
159pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.32203413
160startle response (GO:0001964)2.31482703
161regulation of synaptic transmission, glutamatergic (GO:0051966)2.30548612
162positive regulation of synapse assembly (GO:0051965)2.29297801
163calcium ion import (GO:0070509)2.29184362
164cerebral cortex radially oriented cell migration (GO:0021799)2.28883578
165sperm capacitation (GO:0048240)2.28795583
166binding of sperm to zona pellucida (GO:0007339)2.28499575
167purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.27780218
168regulation of respiratory gaseous exchange (GO:0043576)2.27761765
169cilium movement (GO:0003341)12.0490604
170axonemal dynein complex assembly (GO:0070286)10.3481282

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.66880267
2EZH2_22144423_ChIP-Seq_EOC_Human4.91417453
3FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.09473104
4GBX2_23144817_ChIP-Seq_PC3_Human2.83439628
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.75797270
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.31247674
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.26281398
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.22462929
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.20901295
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14551697
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.11921912
12AR_21572438_ChIP-Seq_LNCaP_Human2.09894798
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.07598862
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.03697332
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.01970218
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.01530062
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.99921594
18ESR1_20079471_ChIP-ChIP_T-47D_Human1.99390377
19ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97209557
20SMC4_20622854_ChIP-Seq_HELA_Human1.96343192
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.92576684
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.90347764
23JARID2_20075857_ChIP-Seq_MESCs_Mouse1.89348120
24AHR_22903824_ChIP-Seq_MCF-7_Human1.88223628
25RUNX1_27514584_Chip-Seq_MCF-7_Human1.87728233
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.87025731
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.86865514
28BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.85663000
29SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.84563354
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.84047877
31DROSHA_22980978_ChIP-Seq_HELA_Human1.83209661
32RNF2_18974828_ChIP-Seq_MESCs_Mouse1.81762504
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.81762504
34REST_21632747_ChIP-Seq_MESCs_Mouse1.81579234
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.81573817
36TAF15_26573619_Chip-Seq_HEK293_Human1.77836679
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.77086046
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76393783
39ESR2_21235772_ChIP-Seq_MCF-7_Human1.73416989
40TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.69931005
41SMAD4_21799915_ChIP-Seq_A2780_Human1.69814197
42P300_19829295_ChIP-Seq_ESCs_Human1.67963103
43FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.66028539
44TP63_22573176_ChIP-Seq_HFKS_Human1.63391873
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.62002198
46ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.61695637
47SOX2_27498859_Chip-Seq_STOMACH_Mouse1.59173637
48STAT1_20625510_ChIP-Seq_HELA_Human1.58850139
49KLF5_25053715_ChIP-Seq_YYC3_Human1.56729773
50VDR_22108803_ChIP-Seq_LS180_Human1.56376220
51TP63_23658742_ChIP-Seq_EP156T_Human1.55391017
52RNF2_27304074_Chip-Seq_NSC_Mouse1.54978878
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51722822
54PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.51062122
55FOXM1_26456572_ChIP-Seq_MCF-7_Human1.49095536
56P63_26484246_Chip-Seq_KERATINOCYTES_Human1.48309453
57ELF1_20517297_ChIP-Seq_JURKAT_Human1.47578061
58PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.47371384
59PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47255976
60TDRD3_21172665_ChIP-Seq_MCF-7_Human1.47013427
61ZNF217_24962896_ChIP-Seq_MCF-7_Human1.46691849
62FUS_26573619_Chip-Seq_HEK293_Human1.45900864
63PIAS1_25552417_ChIP-Seq_VCAP_Human1.43512119
64CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43208914
65ETV1_20927104_ChIP-Seq_GIST48_Human1.43009646
66AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.42132482
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41744209
68SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.41395266
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.40600387
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.40370524
71CTCF_27219007_Chip-Seq_Bcells_Human1.40123171
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38326238
73ESR1_21235772_ChIP-Seq_MCF-7_Human1.37415124
74ZNF274_21170338_ChIP-Seq_K562_Hela1.36108101
75RAD21_21589869_ChIP-Seq_MESCs_Mouse1.35587205
76SOX9_24532713_ChIP-Seq_HFSC_Mouse1.35064699
77BMI1_23680149_ChIP-Seq_NPCS_Mouse1.34929677
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34851091
79SMRT_27268052_Chip-Seq_Bcells_Human1.34751691
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34543332
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34298996
82HNFA_21074721_ChIP-Seq_CACO-2_Human1.33811401
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.33612438
84CTNNB1_20460455_ChIP-Seq_HCT116_Human1.32947943
85PHF8_20622853_ChIP-Seq_HELA_Human1.32293827
86CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.32086448
87YY1_22570637_ChIP-Seq_MALME-3M_Human1.30960686
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.30943107
89EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.30723039
90P68_20966046_ChIP-Seq_HELA_Human1.29699549
91PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.28693095
92ER_23166858_ChIP-Seq_MCF-7_Human1.28519679
93POU3F2_20337985_ChIP-ChIP_501MEL_Human1.28506411
94TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.27930751
95ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.26605250
96OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26449402
97CTCF_20526341_ChIP-Seq_ESCs_Human1.26309810
98RING1B_27294783_Chip-Seq_ESCs_Mouse1.25721649
99NANOG_18555785_Chip-Seq_ESCs_Mouse1.25618875
100NR3C1_21868756_ChIP-Seq_MCF10A_Human1.24099968
101IKZF1_21737484_ChIP-ChIP_HCT116_Human1.23849711
102FLI1_27457419_Chip-Seq_LIVER_Mouse1.23152047
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22842743
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22842743
105PCGF2_27294783_Chip-Seq_ESCs_Mouse1.21730215
106SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21279797
107RBPJ_21746931_ChIP-Seq_IB4_Human1.20410211
108SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20063123
109PHF8_20622854_ChIP-Seq_HELA_Human1.19867039
110SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19803420
111STAT3_23295773_ChIP-Seq_U87_Human1.19677678
112GATA1_19941826_ChIP-Seq_K562_Human1.19517643
113FOXA1_25552417_ChIP-Seq_VCAP_Human1.19487196
114BCAT_22108803_ChIP-Seq_LS180_Human1.18068835
115PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.18001918
116AR_25329375_ChIP-Seq_VCAP_Human1.17519699
117REST_18959480_ChIP-ChIP_MESCs_Mouse1.13588008
118CBX2_22325352_ChIP-Seq_293T-Rex_Human1.12997988
119MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12534368
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12317754
121LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10690778
122E2F1_18555785_Chip-Seq_ESCs_Mouse1.09594650
123P53_22387025_ChIP-Seq_ESCs_Mouse1.09572229
124GATA6_21074721_ChIP-Seq_CACO-2_Human1.09460392
125KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09133169
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09053465
127KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08844406
128TP53_18474530_ChIP-ChIP_U2OS_Human1.08486350
129WDR5_24793694_ChIP-Seq_LNCAP_Human1.07947857
130NFE2_27457419_Chip-Seq_LIVER_Mouse1.07183581
131MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.07075633
132CBP_20019798_ChIP-Seq_JUKART_Human1.06902461
133IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.06902461
134SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.06599391
135TCF4_23295773_ChIP-Seq_U87_Human1.06292354
136KDM2B_26808549_Chip-Seq_REH_Human1.06025544
137MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05974361
138GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.05944122
139AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.05941053
140NFYA_21822215_ChIP-Seq_K562_Human1.05735911
141EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.05704423
142EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.05687166
143SMAD4_21741376_ChIP-Seq_EPCs_Human1.05296449
144ARNT_22903824_ChIP-Seq_MCF-7_Human1.05234549
145CEBPB_22108803_ChIP-Seq_LS180_Human1.05162417
146SOX2_20726797_ChIP-Seq_SW620_Human1.05123244
147ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04464411
148CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03806835
149CREB1_26743006_Chip-Seq_LNCaP_Human1.03786495
150IGF1R_20145208_ChIP-Seq_DFB_Human1.03507082
151RARB_27405468_Chip-Seq_BRAIN_Mouse1.03191441
152SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.03012753
153P300_27268052_Chip-Seq_Bcells_Human1.02374038
154P300_18555785_Chip-Seq_ESCs_Mouse1.02348503
155SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02283797
156FOXO3_23340844_ChIP-Seq_DLD1_Human1.02245069
157PRDM14_20953172_ChIP-Seq_ESCs_Human1.02237637
158NFYB_21822215_ChIP-Seq_K562_Human1.02067268
159CMYC_18555785_Chip-Seq_ESCs_Mouse1.01991074
160RUNX2_22187159_ChIP-Seq_PCA_Human1.01281130
161E2F1_20622854_ChIP-Seq_HELA_Human1.01087056
162TBL1_22424771_ChIP-Seq_293T_Human0.99565028
163CDX2_20551321_ChIP-Seq_CACO-2_Human0.99353830
164EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99277097
165STAT6_21828071_ChIP-Seq_BEAS2B_Human0.98623099
166GATA4_25053715_ChIP-Seq_YYC3_Human0.98346067
167PPAR_26484153_Chip-Seq_NCI-H1993_Human0.98309730
168CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97830841
169CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97054132
170FOXA2_19822575_ChIP-Seq_HepG2_Human0.96152602
171VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95563805
172SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95551096
173STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.94413890
174LXR_22292898_ChIP-Seq_THP-1_Human0.93964911
175SMAD3_21741376_ChIP-Seq_HESCs_Human0.93171611
176BCOR_27268052_Chip-Seq_Bcells_Human0.92432959
177SOX2_21211035_ChIP-Seq_LN229_Human0.91822122
178RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.90792485
179FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.90139654
180GATA3_24758297_ChIP-Seq_MCF-7_Human0.89257862
181SMAD4_21741376_ChIP-Seq_HESCs_Human0.89190806
182MYC_19829295_ChIP-Seq_ESCs_Human0.88401702
183ERG_20517297_ChIP-Seq_VCAP_Human0.88056841

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.23158493
2MP0003136_yellow_coat_color6.07666737
3MP0002132_abnormal_respiratory_system5.18779865
4MP0005410_abnormal_fertilization3.69022509
5MP0003880_abnormal_central_pattern3.64328528
6MP0004043_abnormal_pH_regulation3.60154116
7MP0002653_abnormal_ependyma_morphology3.54001476
8MP0002277_abnormal_respiratory_mucosa3.39655585
9MP0004859_abnormal_synaptic_plasticity3.29772530
10MP0000566_synostosis3.17617421
11MP0008789_abnormal_olfactory_epithelium3.16336271
12MP0005646_abnormal_pituitary_gland3.01460962
13MP0001984_abnormal_olfaction2.84757593
14MP0002736_abnormal_nociception_after2.70602077
15MP0001968_abnormal_touch/_nociception2.68146804
16MP0001440_abnormal_grooming_behavior2.67492243
17MP0003635_abnormal_synaptic_transmissio2.49335010
18MP0009745_abnormal_behavioral_response2.39231855
19MP0001486_abnormal_startle_reflex2.30874655
20MP0005623_abnormal_meninges_morphology2.30575647
21MP0004270_analgesia2.29171791
22MP0000778_abnormal_nervous_system2.25064022
23MP0001501_abnormal_sleep_pattern2.23843728
24MP0000383_abnormal_hair_follicle2.22009624
25MP0002572_abnormal_emotion/affect_behav2.18848522
26MP0002063_abnormal_learning/memory/cond2.10104599
27MP0009046_muscle_twitch2.06789007
28MP0005083_abnormal_biliary_tract2.05341667
29MP0002064_seizures2.03071190
30MP0008004_abnormal_stomach_pH1.99600903
31MP0010678_abnormal_skin_adnexa1.86044615
32MP0004019_abnormal_vitamin_homeostasis1.84519567
33MP0002168_other_aberrant_phenotype1.82317375
34MP0001188_hyperpigmentation1.81294906
35MP0004858_abnormal_nervous_system1.81162200
36MP0002272_abnormal_nervous_system1.79810302
37MP0003656_abnormal_erythrocyte_physiolo1.76889888
38MP0000678_abnormal_parathyroid_gland1.75796151
39MP0004381_abnormal_hair_follicle1.75302849
40MP0002734_abnormal_mechanical_nocicepti1.74741344
41MP0001765_abnormal_ion_homeostasis1.73705052
42MP0002557_abnormal_social/conspecific_i1.68807919
43MP0002735_abnormal_chemical_nociception1.67050382
44MP0003698_abnormal_male_reproductive1.63931504
45MP0005409_darkened_coat_color1.62603118
46MP0001346_abnormal_lacrimal_gland1.60500603
47MP0005248_abnormal_Harderian_gland1.59509475
48MP0002067_abnormal_sensory_capabilities1.58911454
49MP0004133_heterotaxia1.50501462
50MP0009379_abnormal_foot_pigmentation1.44050942
51MP0003634_abnormal_glial_cell1.39628174
52MP0004742_abnormal_vestibular_system1.38602521
53MP0001485_abnormal_pinna_reflex1.37965207
54MP0003329_amyloid_beta_deposits1.35573035
55MP0003690_abnormal_glial_cell1.33641369
56MP0005423_abnormal_somatic_nervous1.32013471
57MP0001529_abnormal_vocalization1.30970210
58MP0006276_abnormal_autonomic_nervous1.28596784
59MP0004885_abnormal_endolymph1.28460223
60MP0002909_abnormal_adrenal_gland1.27942229
61MP0001502_abnormal_circadian_rhythm1.27071090
62MP0000631_abnormal_neuroendocrine_gland1.25901839
63MP0005551_abnormal_eye_electrophysiolog1.25776751
64MP0005395_other_phenotype1.25545547
65MP0004142_abnormal_muscle_tone1.22324103
66MP0002184_abnormal_innervation1.18788312
67MP0006292_abnormal_olfactory_placode1.18435774
68MP0003950_abnormal_plasma_membrane1.14498435
69MP0003633_abnormal_nervous_system1.14495702
70MP0005377_hearing/vestibular/ear_phenot1.13734451
71MP0003878_abnormal_ear_physiology1.13734451
72MP0002152_abnormal_brain_morphology1.13167373
73MP0002882_abnormal_neuron_morphology1.12095374
74MP0005636_abnormal_mineral_homeostasis1.08955799
75MP0001929_abnormal_gametogenesis1.08118935
76MP0001970_abnormal_pain_threshold1.07972737
77MP0002938_white_spotting1.07834786
78MP0004145_abnormal_muscle_electrophysio1.07824756
79MP0002249_abnormal_larynx_morphology1.06504171
80MP0002638_abnormal_pupillary_reflex1.04713023
81MP0010030_abnormal_orbit_morphology1.03567199
82MP0000026_abnormal_inner_ear1.03321512
83MP0002102_abnormal_ear_morphology1.01621562
84MP0002282_abnormal_trachea_morphology1.01308410
85MP0003938_abnormal_ear_development0.99106999
86MP0002928_abnormal_bile_duct0.98896227
87MP0005165_increased_susceptibility_to0.98101017
88MP0009780_abnormal_chondrocyte_physiolo0.97495429
89MP0005386_behavior/neurological_phenoty0.96726929
90MP0004924_abnormal_behavior0.96726929
91MP0002733_abnormal_thermal_nociception0.95560607
92MP0002752_abnormal_somatic_nervous0.95333219
93MP0008569_lethality_at_weaning0.95141853
94MP0000955_abnormal_spinal_cord0.94756135
95MP0000465_gastrointestinal_hemorrhage0.93703971
96MP0000049_abnormal_middle_ear0.92219381
97MP0005645_abnormal_hypothalamus_physiol0.91519221
98MP0002066_abnormal_motor_capabilities/c0.91042790
99MP0001963_abnormal_hearing_physiology0.89902887
100MP0000681_abnormal_thyroid_gland0.87981448
101MP0001905_abnormal_dopamine_level0.86956570
102MP0004811_abnormal_neuron_physiology0.86896407
103MP0003861_abnormal_nervous_system0.85656001
104MP0002161_abnormal_fertility/fecundity0.84782011
105MP0002876_abnormal_thyroid_physiology0.84775450
106MP0002233_abnormal_nose_morphology0.83353124
107MP0010155_abnormal_intestine_physiology0.82537740
108MP0010234_abnormal_vibrissa_follicle0.82112483
109MP0003631_nervous_system_phenotype0.81948852
110MP0001270_distended_abdomen0.80929357
111MP0000920_abnormal_myelination0.80517765
112MP0009250_abnormal_appendicular_skeleto0.79680547
113MP0005164_abnormal_response_to0.79458372
114MP0001958_emphysema0.78067176
115MP0001293_anophthalmia0.78044653
116MP0005595_abnormal_vascular_smooth0.77727037
117MP0009643_abnormal_urine_homeostasis0.76370578
118MP0003303_peritoneal_inflammation0.75636178
119MP0001849_ear_inflammation0.75071232
120MP0002136_abnormal_kidney_physiology0.74621093
121MP0001664_abnormal_digestion0.72446405
122MP0005365_abnormal_bile_salt0.72252832
123MP0005408_hypopigmentation0.71857967
124MP0001299_abnormal_eye_distance/0.70077906
125MP0005388_respiratory_system_phenotype0.70014169
126MP0002133_abnormal_respiratory_system0.70014169
127MP0003937_abnormal_limbs/digits/tail_de0.69092358
128MP0005389_reproductive_system_phenotype0.68427558
129MP0004883_abnormal_blood_vessel0.68293647
130MP0002160_abnormal_reproductive_system0.66916457
131MP0002116_abnormal_craniofacial_bone0.66749018
132MP0003122_maternal_imprinting0.66298018
133MP0002229_neurodegeneration0.66278722
134MP0005253_abnormal_eye_physiology0.65814981
135MP0005499_abnormal_olfactory_system0.64781518
136MP0005394_taste/olfaction_phenotype0.64781518
137MP0005167_abnormal_blood-brain_barrier0.63579241
138MP0004264_abnormal_extraembryonic_tissu0.63249844
139MP0002822_catalepsy0.63147574
140MP0005310_abnormal_salivary_gland0.62648867
141MP0005085_abnormal_gallbladder_physiolo0.61633280
142MP0002210_abnormal_sex_determination0.61129514
143MP0003075_altered_response_to0.60681854
144MP0001177_atelectasis0.60546050
145MP0002405_respiratory_system_inflammati0.55578393
146MP0000467_abnormal_esophagus_morphology0.55391049
147MP0002098_abnormal_vibrissa_morphology0.54165499
148MP0002139_abnormal_hepatobiliary_system0.53865122
149MP0003453_abnormal_keratinocyte_physiol0.53257135
150MP0001324_abnormal_eye_pigmentation0.52776896
151MP0009765_abnormal_xenobiotic_induced0.52551832
152MP0005220_abnormal_exocrine_pancreas0.52135570
153MP0005391_vision/eye_phenotype0.51086990
154MP0001879_abnormal_lymphatic_vessel0.48562968
155MP0005195_abnormal_posterior_eye0.47103462
156MP0009703_decreased_birth_body0.46518946
157MP0001944_abnormal_pancreas_morphology0.45059662
158MP0001666_abnormal_nutrient_absorption0.42199581
159MP0002896_abnormal_bone_mineralization0.39676356
160MP0005503_abnormal_tendon_morphology0.39077224
161MP0002092_abnormal_eye_morphology0.38358461

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.94776762
2Rhinitis (HP:0012384)8.90228436
3Dynein arm defect of respiratory motile cilia (HP:0012255)8.64760868
4Absent/shortened dynein arms (HP:0200106)8.64760868
5Abnormal respiratory epithelium morphology (HP:0012253)8.15849558
6Abnormal respiratory motile cilium morphology (HP:0005938)8.15849558
7Chronic bronchitis (HP:0004469)6.69672730
8Bronchiectasis (HP:0002110)4.60808152
9Tubulointerstitial nephritis (HP:0001970)4.04647457
10Pancreatic fibrosis (HP:0100732)3.87379666
11Nasal polyposis (HP:0100582)3.82997712
12True hermaphroditism (HP:0010459)3.72719420
13Bile duct proliferation (HP:0001408)3.45392309
14Abnormal biliary tract physiology (HP:0012439)3.45392309
15Nephronophthisis (HP:0000090)3.39673715
16Recurrent sinusitis (HP:0011108)3.16911291
17Molar tooth sign on MRI (HP:0002419)3.16696974
18Abnormality of midbrain morphology (HP:0002418)3.16696974
19Bronchitis (HP:0012387)3.10471748
20Abnormality of the nasal mucosa (HP:0000433)3.07119583
21Chronic otitis media (HP:0000389)2.96917713
22Pancreatic cysts (HP:0001737)2.91615977
23Cystic liver disease (HP:0006706)2.82244912
24Tubular atrophy (HP:0000092)2.81590810
25Abnormality of the renal medulla (HP:0100957)2.79108336
26Chronic hepatic failure (HP:0100626)2.76946830
27Occipital encephalocele (HP:0002085)2.76373145
28Medial flaring of the eyebrow (HP:0010747)2.76334264
29Hyperactive renin-angiotensin system (HP:0000841)2.74791416
30Chronic sinusitis (HP:0011109)2.60526039
31Congenital hepatic fibrosis (HP:0002612)2.55572030
32Postaxial foot polydactyly (HP:0001830)2.53544112
33Median cleft lip (HP:0000161)2.53503509
34Infertility (HP:0000789)2.47455557
35Recurrent otitis media (HP:0000403)2.45237815
36Tubulointerstitial abnormality (HP:0001969)2.45014835
37Gait imbalance (HP:0002141)2.43734250
38Supernumerary spleens (HP:0009799)2.39438649
39Bell-shaped thorax (HP:0001591)2.34926943
40Congenital primary aphakia (HP:0007707)2.34926462
41Abnormality of dentin (HP:0010299)2.34778821
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.31516953
43Fibular hypoplasia (HP:0003038)2.25768994
44Focal motor seizures (HP:0011153)2.16122212
45Stage 5 chronic kidney disease (HP:0003774)2.15547675
46Abnormality of permanent molar morphology (HP:0011071)2.09161746
47Abnormality of the dental root (HP:0006486)2.09161746
48Taurodontia (HP:0000679)2.09161746
49Preaxial hand polydactyly (HP:0001177)2.07960993
50Abnormality of the dental pulp (HP:0006479)2.05876648
51Abnormal drinking behavior (HP:0030082)2.05675067
52Polydipsia (HP:0001959)2.05675067
53Nephrogenic diabetes insipidus (HP:0009806)2.05228175
54Recurrent bronchitis (HP:0002837)2.05203738
55Insidious onset (HP:0003587)2.02463197
56Termporal pattern (HP:0011008)2.02463197
57Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8308597
58Abnormal respiratory motile cilium physiology (HP:0012261)10.7325674
59Postaxial hand polydactyly (HP:0001162)1.99641769
60Abnormality of molar (HP:0011077)1.98417917
61Abnormality of molar morphology (HP:0011070)1.98417917
62Neurofibrillary tangles (HP:0002185)1.97306037
63Anencephaly (HP:0002323)1.96403523
64Epileptic encephalopathy (HP:0200134)1.91133548
65Sclerocornea (HP:0000647)1.87640180
66Absent frontal sinuses (HP:0002688)1.85068464
67Genital tract atresia (HP:0001827)1.84150343
68Male pseudohermaphroditism (HP:0000037)1.79742981
69Sex reversal (HP:0012245)1.76458383
70Abnormal sex determination (HP:0012244)1.76458383
71Hyperkalemia (HP:0002153)1.76147805
72Abnormality of the renal cortex (HP:0011035)1.75042433
73Renal salt wasting (HP:0000127)1.72909625
74Aplasia/Hypoplasia of the fibula (HP:0006492)1.72329564
75Vaginal atresia (HP:0000148)1.71577126
76Peripheral hypomyelination (HP:0007182)1.67279032
77Asplenia (HP:0001746)1.66519853
78Cerebral inclusion bodies (HP:0100314)1.66115271
79Poor coordination (HP:0002370)1.66113024
80Aplasia/Hypoplasia of the spleen (HP:0010451)1.65334838
81Male infertility (HP:0003251)1.62970658
82Decreased circulating renin level (HP:0003351)1.61756193
83Atelectasis (HP:0100750)1.60580641
84Focal seizures (HP:0007359)1.60237870
85Oculomotor apraxia (HP:0000657)1.58171590
86Hyperventilation (HP:0002883)1.58089897
87Back pain (HP:0003418)1.57747435
88Ulnar claw (HP:0001178)1.56669230
89Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.56037428
90Hemiparesis (HP:0001269)1.55983308
91Concave nail (HP:0001598)1.50897516
92Retinal dysplasia (HP:0007973)1.46660823
93Abnormality of binocular vision (HP:0011514)1.46385680
94Diplopia (HP:0000651)1.46385680
95Broad distal phalanx of finger (HP:0009836)1.46279136
96Neonatal short-limb short stature (HP:0008921)1.46268405
97Megalencephaly (HP:0001355)1.45965936
98Aplasia/Hypoplasia of the lens (HP:0008063)1.45774886
99Degeneration of the lateral corticospinal tracts (HP:0002314)1.45004014
100Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.45004014
101Furrowed tongue (HP:0000221)1.44837981
102Aplasia involving bones of the upper limbs (HP:0009823)1.44266399
103Aplasia of the phalanges of the hand (HP:0009802)1.44266399
104Aplasia involving bones of the extremities (HP:0009825)1.44266399
105Nephropathy (HP:0000112)1.44096755
106Atonic seizures (HP:0010819)1.42218317
107Short nail (HP:0001799)1.40850137
108Hyperaldosteronism (HP:0000859)1.38849644
109Abdominal situs inversus (HP:0003363)1.38685823
110Abnormality of abdominal situs (HP:0011620)1.38685823
111Absent rod-and cone-mediated responses on ERG (HP:0007688)1.37413156
112Cone-rod dystrophy (HP:0000548)1.34886868
113Polyuria (HP:0000103)1.33316819
114Abnormality of the axillary hair (HP:0100134)1.31613980
115Abnormality of secondary sexual hair (HP:0009888)1.31613980
116Abnormality of chloride homeostasis (HP:0011422)1.31416017
117Abnormality of the frontal sinuses (HP:0002687)1.27850086
118Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.25884990
119Short thorax (HP:0010306)1.25108449
120Decreased central vision (HP:0007663)1.24818179
121Abnormality of renin-angiotensin system (HP:0000847)1.23895509
122Hand muscle atrophy (HP:0009130)1.19525057
123Hyponatremia (HP:0002902)1.17846007
124Fetal akinesia sequence (HP:0001989)1.17386856
125Glucose intolerance (HP:0000833)1.13995436
126Hypokalemic alkalosis (HP:0001949)1.13421989
127Bifid scrotum (HP:0000048)1.11759308
128Abnormal rod and cone electroretinograms (HP:0008323)1.08521697
129Abnormality of the distal phalanges of the toes (HP:0010182)1.05914066
130Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.04109264
131Abnormality of macular pigmentation (HP:0008002)1.03323884
132Short femoral neck (HP:0100864)1.02579011
133Renal dysplasia (HP:0000110)0.99244374
134Aplasia of the musculature (HP:0100854)0.96220120
135Popliteal pterygium (HP:0009756)0.95897753
136Short ribs (HP:0000773)0.94878588

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK155.44819792
2PNCK5.27762127
3EPHA24.15300166
4CASK4.03270165
5PASK3.75430902
6EPHA43.07730461
7NTRK32.41667613
8CAMKK12.34284466
9NTRK22.22562004
10TNIK2.16813527
11MUSK2.16212259
12PRKD32.00834821
13MAP3K41.98830578
14MAPKAPK31.98271163
15PTK2B1.97331526
16MAPK131.87647228
17MAP3K21.84560338
18PDK41.77985791
19PDK31.77985791
20RIPK41.74985101
21MAP2K71.67695321
22NEK61.62105364
23TESK11.60703279
24SMG11.56135847
25GRK11.53806080
26EEF2K1.44844821
27STK241.43972132
28CSK1.43814759
29MKNK21.43657219
30FES1.38985730
31TTK1.36666847
32TSSK61.34383803
33PDK21.32545182
34MINK11.32443757
35MAP3K31.28504006
36SIK11.25135014
37MST1R1.24939416
38EPHB11.19231881
39STK391.17866896
40PRKCG1.16392780
41PLK21.12970799
42ROCK21.05783217
43IRAK11.05638135
44MAP3K71.05283397
45CAMK2B1.04079301
46STK381.04054393
47FGR1.00919217
48MAP2K41.00355171
49SIK20.99609036
50CAMK2A0.99228460
51MARK10.97519071
52LRRK20.97081518
53SIK30.96312152
54DMPK0.95270768
55PAK20.94754865
56DYRK1A0.93555057
57CDK30.92800747
58STK100.91864986
59PHKG10.91196992
60PHKG20.91196992
61EPHA30.89959966
62CDK50.84340796
63PAK60.82259485
64TLK10.82035302
65WNK10.77271982
66IRAK20.77166415
67NTRK10.76033742
68BMPR20.74274977
69PAK30.73287899
70TBK10.73106794
71MAP2K20.71011087
72TRPM70.70035853
73GRK50.69339290
74WNK40.68710442
75DAPK20.68559566
76VRK10.66596414
77STK160.66562474
78LMTK20.66219659
79DYRK1B0.65489240
80NME10.63957086
81PRKCE0.63922844
82MAPKAPK50.63727484
83ICK0.63682507
84BMPR1B0.62656074
85BLK0.62077692
86CAMK2D0.60574148
87ERBB20.59344228
88STK30.58267959
89PRKCI0.57706334
90PLK40.56866550
91MAPK70.56830490
92GRK70.56545713
93PRKCQ0.56463208
94PRKD20.54819542
95WEE10.54118738
96MAPK120.53570209
97OXSR10.52821792
98ADRBK10.52375484
99MARK20.52061500
100KSR10.52012377
101PDPK10.51789398
102ERBB30.51193603
103STK38L0.50871793
104FYN0.49721157
105BRSK20.49446304
106GRK60.47916237
107MST40.46340379
108CAMK2G0.45377592
109LATS10.42013416
110ROCK10.41996605
111DDR20.41589713
112PRKG10.41432728
113FER0.40646230
114SGK10.40627102
115PRKACA0.39372943
116INSRR0.39181760
117STK110.38825075
118TRIB30.38744135
119CDK140.37978509
120CDK180.37929378
121RPS6KA20.37678670
122BCR0.37442280
123PRKAA20.36908776
124CDK150.36680036
125AURKA0.36333947
126PRKCD0.36288033
127MET0.36094939
128TYRO30.35460102
129PBK0.34926264
130CAMK1G0.34741186
131PRKCZ0.33211830
132MAP2K10.33010164
133CDK80.32188421
134CDC42BPA0.32031114
135SRC0.31436820
136PRKCA0.31390563
137RIPK10.31058495
138YES10.30872305
139FGFR30.30326109
140MAPK100.30038243
141HIPK20.28292101
142RPS6KB20.27980794
143NLK0.24674492
144TAOK10.23417239
145AKT20.21200130
146PDK10.20086957
147MAP3K120.20020401
148PTK60.19540587
149CAMKK20.17035824
150ABL10.16800626
151SGK4940.16248610
152SGK2230.16248610
153PAK40.15926177
154NEK90.14211740
155BRD40.13396744
156PLK10.11785750
157TYK20.11070726
158MAP4K20.10898381
159RET0.10706859

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009805.37665549
2Phenylalanine metabolism_Homo sapiens_hsa003604.89274366
3Histidine metabolism_Homo sapiens_hsa003404.55532994
4Chemical carcinogenesis_Homo sapiens_hsa052044.31052216
5Drug metabolism - cytochrome P450_Homo sapiens_hsa009824.12309688
6Nicotine addiction_Homo sapiens_hsa050333.72534680
7Tyrosine metabolism_Homo sapiens_hsa003503.72021237
8Olfactory transduction_Homo sapiens_hsa047403.22541040
9beta-Alanine metabolism_Homo sapiens_hsa004102.96841369
10Circadian entrainment_Homo sapiens_hsa047132.49661679
11Glutamatergic synapse_Homo sapiens_hsa047242.46443043
12Glutathione metabolism_Homo sapiens_hsa004802.39694282
13Retinol metabolism_Homo sapiens_hsa008302.35687783
14Amphetamine addiction_Homo sapiens_hsa050312.35661831
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.35554332
16Morphine addiction_Homo sapiens_hsa050322.19399774
17Salivary secretion_Homo sapiens_hsa049702.18608344
18GABAergic synapse_Homo sapiens_hsa047272.11367828
19Gastric acid secretion_Homo sapiens_hsa049712.08511170
20Taste transduction_Homo sapiens_hsa047422.08033781
21Caffeine metabolism_Homo sapiens_hsa002322.03645456
22Calcium signaling pathway_Homo sapiens_hsa040202.01473729
23Long-term potentiation_Homo sapiens_hsa047201.97250528
24Renin secretion_Homo sapiens_hsa049241.86625229
25Linoleic acid metabolism_Homo sapiens_hsa005911.86385295
26Insulin secretion_Homo sapiens_hsa049111.83597257
27Phototransduction_Homo sapiens_hsa047441.80587071
28Dorso-ventral axis formation_Homo sapiens_hsa043201.78860246
29Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.78017769
30Fatty acid biosynthesis_Homo sapiens_hsa000611.72965765
31ABC transporters_Homo sapiens_hsa020101.70729456
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69186945
33Nitrogen metabolism_Homo sapiens_hsa009101.64766225
34Dopaminergic synapse_Homo sapiens_hsa047281.58658018
35Serotonergic synapse_Homo sapiens_hsa047261.53100769
36cAMP signaling pathway_Homo sapiens_hsa040241.51749234
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.51103173
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48229014
39Cocaine addiction_Homo sapiens_hsa050301.42987808
40Fatty acid degradation_Homo sapiens_hsa000711.42972833
41Tight junction_Homo sapiens_hsa045301.41649283
42Huntingtons disease_Homo sapiens_hsa050161.40356774
43Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.38754968
44Axon guidance_Homo sapiens_hsa043601.37315467
45Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.34983182
46Oxytocin signaling pathway_Homo sapiens_hsa049211.33643581
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.30411711
48Melanogenesis_Homo sapiens_hsa049161.25515597
49Long-term depression_Homo sapiens_hsa047301.25085248
50Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.23484119
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22916503
52GnRH signaling pathway_Homo sapiens_hsa049121.19815280
53Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.19804872
54Cardiac muscle contraction_Homo sapiens_hsa042601.18887455
55cGMP-PKG signaling pathway_Homo sapiens_hsa040221.18814457
56Estrogen signaling pathway_Homo sapiens_hsa049151.16832555
57Gap junction_Homo sapiens_hsa045401.13814098
58Peroxisome_Homo sapiens_hsa041461.13500508
59Synaptic vesicle cycle_Homo sapiens_hsa047211.11317396
60Cholinergic synapse_Homo sapiens_hsa047251.10643040
61Circadian rhythm_Homo sapiens_hsa047101.06254724
62African trypanosomiasis_Homo sapiens_hsa051431.04642332
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.00863501
64Notch signaling pathway_Homo sapiens_hsa043300.99342793
65Arachidonic acid metabolism_Homo sapiens_hsa005900.97081313
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97055101
67Pancreatic secretion_Homo sapiens_hsa049720.96472119
68Mineral absorption_Homo sapiens_hsa049780.94767209
69Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94469845
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.94277614
71Starch and sucrose metabolism_Homo sapiens_hsa005000.93893000
72Glucagon signaling pathway_Homo sapiens_hsa049220.93740346
73PPAR signaling pathway_Homo sapiens_hsa033200.93588313
74Wnt signaling pathway_Homo sapiens_hsa043100.93270806
75Alzheimers disease_Homo sapiens_hsa050100.92870732
76Collecting duct acid secretion_Homo sapiens_hsa049660.92580723
77Hedgehog signaling pathway_Homo sapiens_hsa043400.91354794
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.91310904
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.89210671
80Ovarian steroidogenesis_Homo sapiens_hsa049130.83158604
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82394976
82Bile secretion_Homo sapiens_hsa049760.79532339
83Thyroid hormone synthesis_Homo sapiens_hsa049180.78894791
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.78414565
85Basal cell carcinoma_Homo sapiens_hsa052170.78296892
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.76656345
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75518785
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73974888
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73115287
90Oxidative phosphorylation_Homo sapiens_hsa001900.72908936
91Ether lipid metabolism_Homo sapiens_hsa005650.69290141
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65684384
93Adherens junction_Homo sapiens_hsa045200.65266100
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.64195885
95Vitamin B6 metabolism_Homo sapiens_hsa007500.64028327
96Leukocyte transendothelial migration_Homo sapiens_hsa046700.63755509
97Prion diseases_Homo sapiens_hsa050200.61372628
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58955758
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56912451
100Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55476075
101Dilated cardiomyopathy_Homo sapiens_hsa054140.54314255
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.52851061
103Arginine and proline metabolism_Homo sapiens_hsa003300.49433730
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49156578
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.48909592
106Hepatitis C_Homo sapiens_hsa051600.48897899
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.48641793
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47753787
109Primary bile acid biosynthesis_Homo sapiens_hsa001200.47463176
110Glycerolipid metabolism_Homo sapiens_hsa005610.46741068
111Steroid biosynthesis_Homo sapiens_hsa001000.46092847
112Ras signaling pathway_Homo sapiens_hsa040140.45757782
113MAPK signaling pathway_Homo sapiens_hsa040100.45717849
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45059741
115Complement and coagulation cascades_Homo sapiens_hsa046100.44076397
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43979645
117ErbB signaling pathway_Homo sapiens_hsa040120.43570324
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.43282456
119Choline metabolism in cancer_Homo sapiens_hsa052310.41947329
120Pyruvate metabolism_Homo sapiens_hsa006200.40496060
121Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39259511
122Rap1 signaling pathway_Homo sapiens_hsa040150.38446340
123Butanoate metabolism_Homo sapiens_hsa006500.36293296
124Propanoate metabolism_Homo sapiens_hsa006400.36133687
125Hippo signaling pathway_Homo sapiens_hsa043900.35425924
126Rheumatoid arthritis_Homo sapiens_hsa053230.35057912
127Fatty acid elongation_Homo sapiens_hsa000620.34796326
128Sphingolipid metabolism_Homo sapiens_hsa006000.34423724
129Hematopoietic cell lineage_Homo sapiens_hsa046400.34372784
130Antigen processing and presentation_Homo sapiens_hsa046120.32677446
131Oocyte meiosis_Homo sapiens_hsa041140.30517401
132Glycosaminoglycan degradation_Homo sapiens_hsa005310.29534437
133Inositol phosphate metabolism_Homo sapiens_hsa005620.29519125
134Vibrio cholerae infection_Homo sapiens_hsa051100.29427594
135Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28655037
136Metabolic pathways_Homo sapiens_hsa011000.28071510
137Vitamin digestion and absorption_Homo sapiens_hsa049770.25411200
138Amoebiasis_Homo sapiens_hsa051460.24335007
139Type I diabetes mellitus_Homo sapiens_hsa049400.23050696
140Endocytosis_Homo sapiens_hsa041440.19529035
141Autoimmune thyroid disease_Homo sapiens_hsa053200.17595007
142Insulin resistance_Homo sapiens_hsa049310.17103496
143Allograft rejection_Homo sapiens_hsa053300.16635727
144Jak-STAT signaling pathway_Homo sapiens_hsa046300.16190679
145Arginine biosynthesis_Homo sapiens_hsa002200.14644709
146Lysosome_Homo sapiens_hsa041420.12905829
147Tryptophan metabolism_Homo sapiens_hsa003800.11906762
148Graft-versus-host disease_Homo sapiens_hsa053320.11691398
149Sphingolipid signaling pathway_Homo sapiens_hsa040710.09812548
150Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.07359847
151alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.07120053
152Prostate cancer_Homo sapiens_hsa052150.06228219

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »