CFAP20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1guanosine-containing compound biosynthetic process (GO:1901070)4.34543189
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.30697183
3deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.12419354
4purine nucleobase biosynthetic process (GO:0009113)4.10214022
5intraciliary transport (GO:0042073)4.03696500
6viral mRNA export from host cell nucleus (GO:0046784)3.97377751
7RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.94464015
8tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.94464015
9nucleobase biosynthetic process (GO:0046112)3.94461894
10cullin deneddylation (GO:0010388)3.93819034
11GTP biosynthetic process (GO:0006183)3.92220339
12DNA deamination (GO:0045006)3.91765801
13establishment of protein localization to mitochondrial membrane (GO:0090151)3.87764148
14protein deneddylation (GO:0000338)3.82288173
15ATP synthesis coupled proton transport (GO:0015986)3.71313990
16energy coupled proton transport, down electrochemical gradient (GO:0015985)3.71313990
17proteasome assembly (GO:0043248)3.62960971
18pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.62482043
19DNA replication initiation (GO:0006270)3.61281516
20UTP biosynthetic process (GO:0006228)3.59702254
21telomere maintenance via semi-conservative replication (GO:0032201)3.56056422
22DNA strand elongation involved in DNA replication (GO:0006271)3.56013968
23rRNA modification (GO:0000154)3.52383795
24DNA strand elongation (GO:0022616)3.52126894
25pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.51313633
26tRNA methylation (GO:0030488)3.47895939
27CTP biosynthetic process (GO:0006241)3.47296000
28CTP metabolic process (GO:0046036)3.47296000
292-deoxyribonucleotide biosynthetic process (GO:0009265)3.43331897
30deoxyribose phosphate biosynthetic process (GO:0046385)3.43331897
31DNA damage response, detection of DNA damage (GO:0042769)3.40579903
32termination of RNA polymerase III transcription (GO:0006386)3.39461039
33transcription elongation from RNA polymerase III promoter (GO:0006385)3.39461039
347-methylguanosine mRNA capping (GO:0006370)3.39367399
35mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.37619583
36CENP-A containing nucleosome assembly (GO:0034080)3.36016581
37rRNA methylation (GO:0031167)3.34988253
38RNA capping (GO:0036260)3.32065848
397-methylguanosine RNA capping (GO:0009452)3.32065848
40chromatin remodeling at centromere (GO:0031055)3.28360648
41chaperone-mediated protein transport (GO:0072321)3.26905161
42pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.26444360
43nonmotile primary cilium assembly (GO:0035058)3.25187273
44DNA double-strand break processing (GO:0000729)3.24558803
45protein-cofactor linkage (GO:0018065)3.23410249
46spliceosomal complex assembly (GO:0000245)3.22926378
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.21827911
48transcription-coupled nucleotide-excision repair (GO:0006283)3.20132851
49GMP metabolic process (GO:0046037)3.19927575
50pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.17873705
51regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.17600177
52histone H2A acetylation (GO:0043968)3.17004713
53deoxyribonucleotide biosynthetic process (GO:0009263)3.15740984
54ribosomal small subunit assembly (GO:0000028)3.14868198
55positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.13754856
56pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.09487072
57UTP metabolic process (GO:0046051)3.08782233
58telomere maintenance via recombination (GO:0000722)3.08722938
59spliceosomal snRNP assembly (GO:0000387)3.07533719
60exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.04761943
61IMP biosynthetic process (GO:0006188)3.04116942
62respiratory electron transport chain (GO:0022904)3.03303233
63DNA ligation (GO:0006266)3.01426327
64nucleotide-excision repair, DNA gap filling (GO:0006297)3.01113946
65anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.01092630
66nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.01063785
67electron transport chain (GO:0022900)3.00577198
68DNA replication-independent nucleosome assembly (GO:0006336)2.98789445
69DNA replication-independent nucleosome organization (GO:0034724)2.98789445
70intra-S DNA damage checkpoint (GO:0031573)2.98080659
71signal peptide processing (GO:0006465)2.96824733
72regulation of nuclear cell cycle DNA replication (GO:0033262)2.96731576
73regulation of cellular amino acid metabolic process (GO:0006521)2.95050939
74axonemal dynein complex assembly (GO:0070286)2.94732471
75pyrimidine nucleotide biosynthetic process (GO:0006221)2.93744351
76protein K6-linked ubiquitination (GO:0085020)2.92617648
77deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.92309712
78formation of translation preinitiation complex (GO:0001731)2.91115121
79protein neddylation (GO:0045116)2.90982858
80regulation of mitochondrial translation (GO:0070129)2.90914736
81organelle disassembly (GO:1903008)2.90640233
82pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.90332963
83protein K11-linked ubiquitination (GO:0070979)2.90266812
84negative regulation of ligase activity (GO:0051352)2.90024843
85negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.90024843
86regulation of hexokinase activity (GO:1903299)2.89628944
87regulation of glucokinase activity (GO:0033131)2.89628944
88water-soluble vitamin biosynthetic process (GO:0042364)2.87653838
89cytochrome complex assembly (GO:0017004)2.86050597
90pseudouridine synthesis (GO:0001522)2.85250019
91DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.84124791
92DNA catabolic process, exonucleolytic (GO:0000738)2.83587603
93mannosylation (GO:0097502)2.83562697
94mitotic recombination (GO:0006312)2.83355346
95DNA integration (GO:0015074)2.83211596
96histone exchange (GO:0043486)2.80888482
97signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.79681853
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.79681853
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.79681853
100positive regulation of mitochondrial fission (GO:0090141)2.79397075
101pyrimidine nucleoside biosynthetic process (GO:0046134)2.79270316
102somatic hypermutation of immunoglobulin genes (GO:0016446)2.78370607
103somatic diversification of immune receptors via somatic mutation (GO:0002566)2.78370607
104pyrimidine-containing compound biosynthetic process (GO:0072528)2.78308558
105DNA replication checkpoint (GO:0000076)2.76763605
106protein targeting to mitochondrion (GO:0006626)2.76219241
107telomere maintenance via telomere lengthening (GO:0010833)2.75635925
108establishment of integrated proviral latency (GO:0075713)2.75363538
109signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.75319082
110intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.75319082
111transcription elongation from RNA polymerase II promoter (GO:0006368)2.75269808
112protein complex biogenesis (GO:0070271)2.75244460
113* regulation of cilium movement (GO:0003352)2.74618052
114nucleobase-containing small molecule interconversion (GO:0015949)2.73813119
115pyrimidine nucleotide catabolic process (GO:0006244)2.73795435
116positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.71911615
117epithelial cilium movement (GO:0003351)2.71066000
118pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.70614341
119signal transduction involved in cell cycle checkpoint (GO:0072395)2.70575610
120replication fork processing (GO:0031297)2.69623600
121regulation of mitotic spindle checkpoint (GO:1903504)2.69088219
122regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.69088219
123establishment of protein localization to mitochondrion (GO:0072655)2.68758421
124mitochondrial respiratory chain complex assembly (GO:0033108)2.68650213
125respiratory chain complex IV assembly (GO:0008535)2.68124991
126signal transduction involved in DNA integrity checkpoint (GO:0072401)2.67515592
127signal transduction involved in DNA damage checkpoint (GO:0072422)2.67515592
128mitochondrial respiratory chain complex I assembly (GO:0032981)2.67477427
129NADH dehydrogenase complex assembly (GO:0010257)2.67477427
130mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.67477427
131RNA methylation (GO:0001510)2.67397735
132establishment of viral latency (GO:0019043)2.67114886
133protein localization to mitochondrion (GO:0070585)2.65974969
134nucleoside diphosphate phosphorylation (GO:0006165)2.65846042
135positive regulation of ligase activity (GO:0051351)2.64640246
136pyrimidine nucleobase catabolic process (GO:0006208)2.64393704
137negative regulation of mitotic sister chromatid separation (GO:2000816)2.63808395
138negative regulation of mitotic sister chromatid segregation (GO:0033048)2.63808395
139negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.63808395
140negative regulation of sister chromatid segregation (GO:0033046)2.63808395
141ribosome biogenesis (GO:0042254)2.63740356
142axoneme assembly (GO:0035082)2.63732395
143L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.56290554
144ubiquinone metabolic process (GO:0006743)2.53861352
145ribonucleoprotein complex disassembly (GO:0032988)2.53103450
146ubiquinone biosynthetic process (GO:0006744)2.52590370
147negative regulation of transcription regulatory region DNA binding (GO:2000678)2.51610954
148microtubule depolymerization (GO:0007019)2.50758263
149DNA replication-dependent nucleosome organization (GO:0034723)2.49249289
150DNA replication-dependent nucleosome assembly (GO:0006335)2.49249289
151intracellular protein transmembrane import (GO:0044743)2.44657164
152regulation of ubiquitin-protein transferase activity (GO:0051438)2.44317222
153platelet dense granule organization (GO:0060155)2.40134557
154lactate metabolic process (GO:0006089)2.39207354
155histone mRNA metabolic process (GO:0008334)2.38473637

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.62098884
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.58041497
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.03025370
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.90330396
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.76783932
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.72458993
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.70130246
8RBPJ_22232070_ChIP-Seq_NCS_Mouse3.57439775
9ELF1_17652178_ChIP-ChIP_JURKAT_Human3.14941942
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.06168618
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.95144785
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.94416396
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.94112390
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.86989408
15ZNF274_21170338_ChIP-Seq_K562_Hela2.85727722
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78376424
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77450733
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.74499682
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.67940582
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.53879830
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.50411828
22VDR_23849224_ChIP-Seq_CD4+_Human2.49861701
23VDR_22108803_ChIP-Seq_LS180_Human2.43400125
24PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.41162640
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.36762824
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.34994729
27FOXP3_21729870_ChIP-Seq_TREG_Human2.34799444
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.31020441
29FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.29694795
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27718689
31XRN2_22483619_ChIP-Seq_HELA_Human2.26526721
32GABP_19822575_ChIP-Seq_HepG2_Human2.25467805
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.25034000
34MYC_19079543_ChIP-ChIP_MESCs_Mouse2.23948209
35DCP1A_22483619_ChIP-Seq_HELA_Human2.15676924
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.08675028
37YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.04099756
38FUS_26573619_Chip-Seq_HEK293_Human2.00023481
39TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.93096702
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92847502
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91163764
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.90815943
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.88520221
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86204159
45IGF1R_20145208_ChIP-Seq_DFB_Human1.86141252
46TP63_19390658_ChIP-ChIP_HaCaT_Human1.86015356
47NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.85633572
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85328590
49FOXM1_23109430_ChIP-Seq_U2OS_Human1.85088950
50ELK1_19687146_ChIP-ChIP_HELA_Human1.81600202
51E2F1_21310950_ChIP-Seq_MCF-7_Human1.80510415
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.79685861
53DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.79595637
54EWS_26573619_Chip-Seq_HEK293_Human1.79114913
55TTF2_22483619_ChIP-Seq_HELA_Human1.78567082
56CIITA_25753668_ChIP-Seq_RAJI_Human1.74592503
57HOXB4_20404135_ChIP-ChIP_EML_Mouse1.71832308
58ZFX_18555785_ChIP-Seq_MESCs_Mouse1.70841234
59CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.61232804
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59876523
61SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57500608
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.57133138
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.50487201
64ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49941189
65KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.44951101
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.44894730
67CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42512164
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.41779568
69TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41435197
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.38832966
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.35387696
72CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.33602951
73P300_19829295_ChIP-Seq_ESCs_Human1.31974027
74POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.31839899
75CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30602672
76MYC_18940864_ChIP-ChIP_HL60_Human1.29903036
77FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.27464089
78SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26863687
79SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.26765489
80KDM5A_27292631_Chip-Seq_BREAST_Human1.24383777
81GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24341129
82TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24052699
83IRF1_19129219_ChIP-ChIP_H3396_Human1.21719262
84BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.20175670
85MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18813370
86GBX2_23144817_ChIP-Seq_PC3_Human1.17598577
87CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.15164108
88ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.15094346
89TAF15_26573619_Chip-Seq_HEK293_Human1.12438377
90CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09999543
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09924582
92SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.09074799
93GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.07981321
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07401228
95CBX2_27304074_Chip-Seq_ESCs_Mouse1.06855757
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05068377
97RNF2_27304074_Chip-Seq_NSC_Mouse1.04334697
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04294534
99FLI1_27457419_Chip-Seq_LIVER_Mouse1.03457506
100TP53_22573176_ChIP-Seq_HFKS_Human1.02560794
101PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01822249
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01662367
103BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98164200
104EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97744564
105CBP_20019798_ChIP-Seq_JUKART_Human0.96806571
106IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96806571
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95888314
108TFEB_21752829_ChIP-Seq_HELA_Human0.94965592
109E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.91431252
110CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91057914
111CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.90594886
112AR_21909140_ChIP-Seq_LNCAP_Human0.90483403
113UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89033206
114POU5F1_16153702_ChIP-ChIP_HESCs_Human0.88431423
115SOX17_20123909_ChIP-Seq_XEN_Mouse0.88071968
116SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.87880210
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.87416174
118TBX5_21415370_ChIP-Seq_HL-1_Mouse0.84851515
119NOTCH1_21737748_ChIP-Seq_TLL_Human0.84739323
120CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84380610
121KLF5_20875108_ChIP-Seq_MESCs_Mouse0.83929592
122ELK1_22589737_ChIP-Seq_MCF10A_Human0.83293991
123BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.82569537
124CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81859004
125CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.79992825
126SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79006140
127TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.77923233
128ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.76887721
129FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.76813404
130SOX2_16153702_ChIP-ChIP_HESCs_Human0.75491610

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.99837170
2MP0008058_abnormal_DNA_repair3.15402666
3MP0006292_abnormal_olfactory_placode2.95110327
4MP0010094_abnormal_chromosome_stability2.88270922
5MP0004957_abnormal_blastocyst_morpholog2.74126543
6MP0003121_genomic_imprinting2.73447005
7MP0008007_abnormal_cellular_replicative2.70218808
8MP0003123_paternal_imprinting2.62401565
9MP0002938_white_spotting2.60723744
10MP0001188_hyperpigmentation2.41640758
11MP0003122_maternal_imprinting2.39464687
12MP0003077_abnormal_cell_cycle2.36071920
13MP0005646_abnormal_pituitary_gland2.34548062
14MP0002102_abnormal_ear_morphology2.33032396
15MP0008877_abnormal_DNA_methylation2.32373866
16MP0003111_abnormal_nucleus_morphology2.29614103
17MP0003880_abnormal_central_pattern2.23613265
18MP0002638_abnormal_pupillary_reflex2.17859530
19MP0001984_abnormal_olfaction2.17447114
20MP0002160_abnormal_reproductive_system2.05065952
21MP0003787_abnormal_imprinting2.04710850
22MP0003136_yellow_coat_color1.98976955
23MP0008789_abnormal_olfactory_epithelium1.90925254
24MP0002736_abnormal_nociception_after1.84754102
25MP0000678_abnormal_parathyroid_gland1.82893041
26MP0009697_abnormal_copulation1.82223200
27MP0008932_abnormal_embryonic_tissue1.79615281
28MP0008057_abnormal_DNA_replication1.76530695
29MP0008995_early_reproductive_senescence1.69506862
30MP0003786_premature_aging1.67478489
31MP0004133_heterotaxia1.66710530
32MP0005220_abnormal_exocrine_pancreas1.63557745
33MP0009046_muscle_twitch1.59008572
34MP0003943_abnormal_hepatobiliary_system1.56632120
35MP0003806_abnormal_nucleotide_metabolis1.52660971
36MP0001968_abnormal_touch/_nociception1.50123930
37MP0005551_abnormal_eye_electrophysiolog1.49171839
38MP0000049_abnormal_middle_ear1.48474290
39MP0003718_maternal_effect1.45708996
40MP0000566_synostosis1.45465637
41MP0003942_abnormal_urinary_system1.45412892
42MP0005389_reproductive_system_phenotype1.44074089
43MP0010030_abnormal_orbit_morphology1.41203697
44MP0000537_abnormal_urethra_morphology1.39056404
45MP0005394_taste/olfaction_phenotype1.38422455
46MP0005499_abnormal_olfactory_system1.38422455
47MP0002210_abnormal_sex_determination1.37811775
48MP0002132_abnormal_respiratory_system1.37533219
49MP0005379_endocrine/exocrine_gland_phen1.36350428
50MP0006054_spinal_hemorrhage1.36271111
51MP0010386_abnormal_urinary_bladder1.32458789
52MP0003937_abnormal_limbs/digits/tail_de1.31236913
53MP0000631_abnormal_neuroendocrine_gland1.31092832
54MP0006035_abnormal_mitochondrial_morpho1.29466857
55MP0003890_abnormal_embryonic-extraembry1.27242050
56MP0003119_abnormal_digestive_system1.27087139
57MP0001529_abnormal_vocalization1.26562972
58MP0005187_abnormal_penis_morphology1.24515141
59MP0002653_abnormal_ependyma_morphology1.23252786
60MP0001293_anophthalmia1.22921881
61MP0002127_abnormal_cardiovascular_syste1.22264727
62MP0004782_abnormal_surfactant_physiolog1.20344848
63MP0000778_abnormal_nervous_system1.19787383
64MP0002751_abnormal_autonomic_nervous1.18600242
65MP0001944_abnormal_pancreas_morphology1.17403477
66MP0002272_abnormal_nervous_system1.16470268
67MP0002234_abnormal_pharynx_morphology1.16388004
68MP0000372_irregular_coat_pigmentation1.16313216
69MP0004142_abnormal_muscle_tone1.13329216
70MP0003283_abnormal_digestive_organ1.12782036
71MP0001929_abnormal_gametogenesis1.12106974
72MP0009745_abnormal_behavioral_response1.11969830
73MP0001145_abnormal_male_reproductive1.11687819
74MP0002233_abnormal_nose_morphology1.11243820
75MP0005075_abnormal_melanosome_morpholog1.09402766
76MP0004215_abnormal_myocardial_fiber1.08433800
77MP0005423_abnormal_somatic_nervous1.08392864
78MP0000647_abnormal_sebaceous_gland1.07391609
79MP0001486_abnormal_startle_reflex1.07109524
80MP0001764_abnormal_homeostasis1.06684254
81MP0001905_abnormal_dopamine_level1.05664494
82MP0005645_abnormal_hypothalamus_physiol1.03795002
83MP0005367_renal/urinary_system_phenotyp1.03390493
84MP0000516_abnormal_urinary_system1.03390493
85MP0002163_abnormal_gland_morphology1.03251970
86MP0000653_abnormal_sex_gland1.03164594
87MP0003567_abnormal_fetal_cardiomyocyte1.03144440
88MP0005391_vision/eye_phenotype1.01348808
89MP0002557_abnormal_social/conspecific_i1.00918814
90MP0009379_abnormal_foot_pigmentation0.99287576
91MP0002572_abnormal_emotion/affect_behav0.98770255
92MP0002877_abnormal_melanocyte_morpholog0.98339464
93MP0000350_abnormal_cell_proliferation0.97621178
94MP0001730_embryonic_growth_arrest0.97160138
95MP0001119_abnormal_female_reproductive0.96608842
96MP0000681_abnormal_thyroid_gland0.95636362
97MP0002734_abnormal_mechanical_nocicepti0.94593054
98MP0006072_abnormal_retinal_apoptosis0.94552874
99MP0003195_calcinosis0.93084035
100MP0006036_abnormal_mitochondrial_physio0.92721648
101MP0003011_delayed_dark_adaptation0.92123359
102MP0001485_abnormal_pinna_reflex0.91999925
103MP0002752_abnormal_somatic_nervous0.90920132
104MP0001697_abnormal_embryo_size0.90891918
105MP0002282_abnormal_trachea_morphology0.90168368
106MP0005084_abnormal_gallbladder_morpholo0.90061461
107MP0002095_abnormal_skin_pigmentation0.87377018
108MP0001286_abnormal_eye_development0.87361117
109MP0003755_abnormal_palate_morphology0.86475541
110MP0003698_abnormal_male_reproductive0.86208317
111MP0001986_abnormal_taste_sensitivity0.85725839
112MP0000955_abnormal_spinal_cord0.85713662
113MP0008875_abnormal_xenobiotic_pharmacok0.84767298
114MP0002184_abnormal_innervation0.84568988
115MP0003315_abnormal_perineum_morphology0.84538147
116MP0002085_abnormal_embryonic_tissue0.83793045
117MP0002735_abnormal_chemical_nociception0.83669064
118MP0001186_pigmentation_phenotype0.83375400
119MP0003861_abnormal_nervous_system0.83111131
120MP0003938_abnormal_ear_development0.83100372
121MP0003635_abnormal_synaptic_transmissio0.82774973
122MP0002693_abnormal_pancreas_physiology0.82637611
123MP0005195_abnormal_posterior_eye0.81754401
124MP0000026_abnormal_inner_ear0.80551930
125MP0002080_prenatal_lethality0.79877125
126MP0008872_abnormal_physiological_respon0.79740646
127MP0009672_abnormal_birth_weight0.78761247
128MP0004147_increased_porphyrin_level0.78523326
129MP0002067_abnormal_sensory_capabilities0.78393475
130MP0005380_embryogenesis_phenotype0.76616732
131MP0001672_abnormal_embryogenesis/_devel0.76616732
132MP0006276_abnormal_autonomic_nervous0.76376149
133MP0001919_abnormal_reproductive_system0.74308982
134MP0004264_abnormal_extraembryonic_tissu0.73957718
135MP0000313_abnormal_cell_death0.73616398
136MP0002396_abnormal_hematopoietic_system0.72361503
137MP0000358_abnormal_cell_content/0.71834022
138MP0005410_abnormal_fertilization0.66563380
139MP0002249_abnormal_larynx_morphology0.66312391
140MP0003186_abnormal_redox_activity0.66210619
141MP0005253_abnormal_eye_physiology0.66119120
142MP0001270_distended_abdomen0.65970056

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic fibrosis (HP:0100732)3.94707200
2True hermaphroditism (HP:0010459)3.86584559
3Chronic bronchitis (HP:0004469)3.62779326
4Pancreatic cysts (HP:0001737)3.45771947
5Birth length less than 3rd percentile (HP:0003561)3.42977580
6Abnormal respiratory motile cilium physiology (HP:0012261)3.33234102
7Type I transferrin isoform profile (HP:0003642)3.31775575
8Abnormal respiratory epithelium morphology (HP:0012253)3.11561276
9Abnormal respiratory motile cilium morphology (HP:0005938)3.11561276
10Abnormal ciliary motility (HP:0012262)3.09230346
11Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.08775173
12Supernumerary spleens (HP:0009799)3.04771971
13Occipital encephalocele (HP:0002085)3.02269237
14Hepatocellular necrosis (HP:0001404)3.01408845
15Facial cleft (HP:0002006)2.98171417
16Molar tooth sign on MRI (HP:0002419)2.97571846
17Abnormality of midbrain morphology (HP:0002418)2.97571846
18Median cleft lip (HP:0000161)2.91534406
19Rhinitis (HP:0012384)2.88447012
20Abnormality of the labia minora (HP:0012880)2.80700459
21Methylmalonic acidemia (HP:0002912)2.69021692
22Hypothermia (HP:0002045)2.68730071
23Abnormal glycosylation (HP:0012345)2.66371490
24Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.66371490
25Abnormal protein N-linked glycosylation (HP:0012347)2.66371490
26Abnormal protein glycosylation (HP:0012346)2.66371490
27Acute necrotizing encephalopathy (HP:0006965)2.66093814
28Medial flaring of the eyebrow (HP:0010747)2.64325080
29Increased hepatocellular lipid droplets (HP:0006565)2.62288036
30Chronic hepatic failure (HP:0100626)2.61388826
3111 pairs of ribs (HP:0000878)2.61226008
32Degeneration of anterior horn cells (HP:0002398)2.55506638
33Abnormality of the anterior horn cell (HP:0006802)2.55506638
34Nephrogenic diabetes insipidus (HP:0009806)2.54915386
35Bifid tongue (HP:0010297)2.53802950
36Hyperglycinemia (HP:0002154)2.51494296
37Congenital primary aphakia (HP:0007707)2.44858735
38Microvesicular hepatic steatosis (HP:0001414)2.40842560
39Lipid accumulation in hepatocytes (HP:0006561)2.40682424
40Nephronophthisis (HP:0000090)2.39602433
41Abnormal mitochondria in muscle tissue (HP:0008316)2.34780782
42Renal Fanconi syndrome (HP:0001994)2.33842937
43Cerebral edema (HP:0002181)2.33427259
44Gait imbalance (HP:0002141)2.32944072
45Aplastic anemia (HP:0001915)2.32579008
46Genital tract atresia (HP:0001827)2.31236962
47Meckel diverticulum (HP:0002245)2.29060881
48Preaxial hand polydactyly (HP:0001177)2.29054658
49Methylmalonic aciduria (HP:0012120)2.28551367
50Postaxial foot polydactyly (HP:0001830)2.27646481
51Patellar aplasia (HP:0006443)2.25951316
52Colon cancer (HP:0003003)2.25366248
53Sclerocornea (HP:0000647)2.22230752
54Optic nerve coloboma (HP:0000588)2.21414369
55Increased serum pyruvate (HP:0003542)2.21196103
56Progressive macrocephaly (HP:0004481)2.19987398
57Lactic acidosis (HP:0003128)2.17742595
58Cystic liver disease (HP:0006706)2.15181258
59Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15155728
60Abnormal lung lobation (HP:0002101)2.13932210
61Abnormality of the ileum (HP:0001549)2.13492099
62Selective tooth agenesis (HP:0001592)2.12118381
63Aplasia/Hypoplasia of the uvula (HP:0010293)2.11410832
64Nephroblastoma (Wilms tumor) (HP:0002667)2.10993889
65Aplasia/Hypoplasia of the tongue (HP:0010295)2.09686733
66Absent thumb (HP:0009777)2.08980763
67Mitochondrial inheritance (HP:0001427)2.08955366
683-Methylglutaconic aciduria (HP:0003535)2.08552246
69Aplasia/Hypoplasia of the patella (HP:0006498)2.06344972
70Optic disc pallor (HP:0000543)2.05278770
71Anencephaly (HP:0002323)2.03870690
72Reticulocytopenia (HP:0001896)2.03575424
73Poor suck (HP:0002033)2.03199035
74Aplasia/Hypoplasia of the sternum (HP:0006714)2.02304908
75Carpal bone hypoplasia (HP:0001498)2.01757279
76Embryonal renal neoplasm (HP:0011794)2.00167103
77Abnormal pancreas size (HP:0012094)1.99893017
78Abnormality of glycolysis (HP:0004366)1.99605136
79Microretrognathia (HP:0000308)1.99442041
80Increased CSF lactate (HP:0002490)1.98442571
81Abnormality of the preputium (HP:0100587)1.97926039
82Acute encephalopathy (HP:0006846)1.93892381
83Hypoglycemic seizures (HP:0002173)1.93660857
84Male pseudohermaphroditism (HP:0000037)1.93579098
85Congenital hepatic fibrosis (HP:0002612)1.91994685
86Medulloblastoma (HP:0002885)1.91228528
87Decreased activity of mitochondrial respiratory chain (HP:0008972)1.90798167
88Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.90798167
89Pendular nystagmus (HP:0012043)1.90640474
90Aganglionic megacolon (HP:0002251)1.89577156
91Broad foot (HP:0001769)1.88909570
92Lissencephaly (HP:0001339)1.88852001
93Chromsome breakage (HP:0040012)1.86286746
94Abnormal biliary tract physiology (HP:0012439)1.86273673
95Bile duct proliferation (HP:0001408)1.86273673
96Generalized aminoaciduria (HP:0002909)1.86072397
97Severe visual impairment (HP:0001141)1.83085242
98Aplasia/Hypoplasia of the fovea (HP:0008060)1.82509019
99Hypoplasia of the fovea (HP:0007750)1.82509019
100Abnormality of alanine metabolism (HP:0010916)1.82490261
101Hyperalaninemia (HP:0003348)1.82490261
102Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82490261
103Symptomatic seizures (HP:0011145)1.82365441
104Poor coordination (HP:0002370)1.81204336
105Cerebral hypomyelination (HP:0006808)1.80056453
106Dynein arm defect of respiratory motile cilia (HP:0012255)1.79502872
107Absent/shortened dynein arms (HP:0200106)1.79502872
108Bone marrow hypocellularity (HP:0005528)1.78593839
109Increased intramyocellular lipid droplets (HP:0012240)1.78282425
110Retinal dysplasia (HP:0007973)1.77819226
111Tubulointerstitial nephritis (HP:0001970)1.77726056
112Aplasia/hypoplasia of the uterus (HP:0008684)1.77177173
113Respiratory failure (HP:0002878)1.77061084
114Specific learning disability (HP:0001328)1.76828865
115Exercise intolerance (HP:0003546)1.76609941
116Abnormality of the renal medulla (HP:0100957)1.74937840
117Short middle phalanx of the 5th finger (HP:0004220)1.74256694
118Prominent metopic ridge (HP:0005487)1.74240671
119Type II lissencephaly (HP:0007260)1.73606618
120Hepatic necrosis (HP:0002605)1.72893257
121Postaxial hand polydactyly (HP:0001162)1.72311850
122Limb dystonia (HP:0002451)1.71707666
123Aplasia/Hypoplasia of the sacrum (HP:0008517)1.70926909
124Postnatal microcephaly (HP:0005484)1.70091525
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.69581044
126Reduced antithrombin III activity (HP:0001976)1.69110740
127Intestinal atresia (HP:0011100)1.67277798
128Vaginal atresia (HP:0000148)1.67216193
129Bronchiectasis (HP:0002110)1.66969876
130Increased serum lactate (HP:0002151)1.66901706
131Leukodystrophy (HP:0002415)1.66859510
132Abnormality of serine family amino acid metabolism (HP:0010894)1.66736361
133Abnormality of glycine metabolism (HP:0010895)1.66736361
134Dandy-Walker malformation (HP:0001305)1.66687030
135Ependymoma (HP:0002888)1.66602330
136Abnormality of cells of the erythroid lineage (HP:0012130)1.66000001
137Horseshoe kidney (HP:0000085)1.65842562
138Decreased testicular size (HP:0008734)1.64138592

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.90252423
2ACVR1B3.60003444
3PASK3.27552512
4BUB13.16772158
5STK38L2.98771001
6WEE12.82825165
7EIF2AK32.72115474
8SRPK12.61347311
9MAPK152.57142334
10PLK42.51090336
11TRIM282.35357829
12MAP4K22.32920993
13VRK12.28189085
14VRK22.23760499
15CDC72.22909562
16STK242.19116005
17MST42.13198130
18ERBB32.09920454
19PIK3CG1.97110107
20AKT31.91976413
21NEK11.82807439
22NUAK11.79423342
23BRSK21.75968588
24BRAF1.74647089
25ZAK1.70359151
26MAP3K41.68255692
27CSNK1G31.67793111
28CDK81.67037888
29PDK21.63161336
30CCNB11.62692290
31TSSK61.58021001
32DYRK31.54862168
33TLK11.54153324
34PLK31.52096872
35CSNK1G21.50784847
36CSNK1G11.50604163
37PLK11.47507973
38EIF2AK11.43786816
39CSNK1A1L1.39410312
40NEK21.37249927
41PBK1.37002418
42EPHA41.36590895
43BCKDK1.33298411
44MKNK21.28824238
45PNCK1.28775583
46MKNK11.25115376
47MARK11.23408613
48TTK1.22036545
49ATR1.17960486
50BRSK11.10763863
51MAPKAPK31.10640976
52WNK31.09550106
53FLT31.06866846
54RPS6KA41.04847650
55AURKA1.04662997
56MAP3K121.03859899
57TIE11.03088661
58CHEK21.01149789
59AURKB1.00445623
60NEK60.99974868
61CDK70.99671859
62BRD40.98921938
63SIK30.98225539
64BMPR1B0.97628284
65INSRR0.96699976
66MAP3K30.93064632
67DYRK20.92494030
68YES10.88720462
69MUSK0.88222416
70FRK0.86671260
71TGFBR10.85983345
72PIM20.84873241
73NME20.84765951
74MINK10.84107296
75TESK10.75375699
76TAOK20.74892046
77BMPR20.74211530
78DAPK10.74151782
79TNIK0.73351751
80STK390.69470143
81MAP2K70.68515123
82EIF2AK20.68343268
83CSNK2A10.68258451
84RPS6KB20.67277767
85MAPK130.65370153
86PAK30.63872366
87ARAF0.62601609
88ATM0.61545919
89TEC0.61172162
90CHEK10.58464177
91RPS6KB10.58311159
92OXSR10.56904733
93CSNK2A20.55691401
94MYLK0.55615039
95KIT0.54551552
96CASK0.54106031
97PRKCE0.53254315
98RPS6KA50.53222472
99ADRBK20.51096363
100EPHA30.48429769
101PLK20.48345839
102CSNK1A10.47455956
103CDK190.43764474
104PINK10.43750192
105BCR0.42898075
106CDK140.42881339
107LIMK10.42615964
108PKN10.42357819
109EPHA20.40183244
110GRK10.39385507
111CSNK1E0.39099489
112FGFR20.39063623
113CDK20.37235051
114DYRK1A0.37046121
115EPHB20.35655264
116NME10.35520936
117CDK10.35282078
118CDK30.34938100
119CDK180.34489757
120PRKD30.34420835
121SGK20.33350203
122ERBB40.32038984
123ADRBK10.31445787
124PRKCI0.31051676
125CSNK1D0.30931567
126UHMK10.29164880
127PRPF4B0.27743150
128RPS6KA60.27084475
129AKT20.27056225
130PRKG20.25482969
131PRKCG0.24890434
132DYRK1B0.24568149
133NLK0.24092248
134NTRK20.23680773
135MATK0.23426702

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.07453558
2Mismatch repair_Homo sapiens_hsa034303.83934844
3RNA polymerase_Homo sapiens_hsa030203.62962379
4Protein export_Homo sapiens_hsa030603.46591842
5Proteasome_Homo sapiens_hsa030503.27939652
6Base excision repair_Homo sapiens_hsa034103.06286239
7Pyrimidine metabolism_Homo sapiens_hsa002402.96843752
8Spliceosome_Homo sapiens_hsa030402.95713923
9Nucleotide excision repair_Homo sapiens_hsa034202.72426765
10Ribosome_Homo sapiens_hsa030102.67520477
11Maturity onset diabetes of the young_Homo sapiens_hsa049502.63677792
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.60251860
13Homologous recombination_Homo sapiens_hsa034402.48182477
14Basal transcription factors_Homo sapiens_hsa030222.45834892
15RNA transport_Homo sapiens_hsa030132.29618999
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.25957297
17Fanconi anemia pathway_Homo sapiens_hsa034602.23962956
18Cell cycle_Homo sapiens_hsa041102.20244544
19RNA degradation_Homo sapiens_hsa030182.06188834
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.04078386
21One carbon pool by folate_Homo sapiens_hsa006702.03682421
22Purine metabolism_Homo sapiens_hsa002301.97336986
23Steroid biosynthesis_Homo sapiens_hsa001001.81503979
24Parkinsons disease_Homo sapiens_hsa050121.77676378
25Huntingtons disease_Homo sapiens_hsa050161.69414452
26Butanoate metabolism_Homo sapiens_hsa006501.66671978
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.66078946
28Propanoate metabolism_Homo sapiens_hsa006401.66046325
29Oxidative phosphorylation_Homo sapiens_hsa001901.64560120
30Fatty acid elongation_Homo sapiens_hsa000621.57965800
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.57591041
32N-Glycan biosynthesis_Homo sapiens_hsa005101.57381553
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.55433799
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50780981
35Non-homologous end-joining_Homo sapiens_hsa034501.49157392
36Folate biosynthesis_Homo sapiens_hsa007901.43769990
37mRNA surveillance pathway_Homo sapiens_hsa030151.40582804
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.32163735
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.30749902
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18962381
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.15324397
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.08702553
43Nicotine addiction_Homo sapiens_hsa050331.04492946
44Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.02754719
45Drug metabolism - other enzymes_Homo sapiens_hsa009830.99978560
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.99569350
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.92833400
48Alzheimers disease_Homo sapiens_hsa050100.90358267
49Peroxisome_Homo sapiens_hsa041460.86792293
50Oocyte meiosis_Homo sapiens_hsa041140.85965595
51Collecting duct acid secretion_Homo sapiens_hsa049660.84334984
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84213620
53SNARE interactions in vesicular transport_Homo sapiens_hsa041300.83366921
54Selenocompound metabolism_Homo sapiens_hsa004500.82415097
55Epstein-Barr virus infection_Homo sapiens_hsa051690.81340964
56Thyroid cancer_Homo sapiens_hsa052160.81239655
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73735636
58p53 signaling pathway_Homo sapiens_hsa041150.72318842
59Regulation of autophagy_Homo sapiens_hsa041400.71930974
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70821910
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69802193
62Vibrio cholerae infection_Homo sapiens_hsa051100.64591972
63Arachidonic acid metabolism_Homo sapiens_hsa005900.63521723
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.62859011
65Tryptophan metabolism_Homo sapiens_hsa003800.60487751
66Fatty acid metabolism_Homo sapiens_hsa012120.59920737
67Sulfur metabolism_Homo sapiens_hsa009200.59430636
68Metabolic pathways_Homo sapiens_hsa011000.59273590
69Olfactory transduction_Homo sapiens_hsa047400.58686686
70Sulfur relay system_Homo sapiens_hsa041220.57592257
71beta-Alanine metabolism_Homo sapiens_hsa004100.56629916
72Galactose metabolism_Homo sapiens_hsa000520.55931101
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.55161366
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.52657976
75Alcoholism_Homo sapiens_hsa050340.52402711
76Insulin secretion_Homo sapiens_hsa049110.51827730
77Fructose and mannose metabolism_Homo sapiens_hsa000510.51774610
78Circadian rhythm_Homo sapiens_hsa047100.51410626
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49359770
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48128563
81Arginine and proline metabolism_Homo sapiens_hsa003300.46941422
82Chemical carcinogenesis_Homo sapiens_hsa052040.46778997
83Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46095011
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44632674
85Nitrogen metabolism_Homo sapiens_hsa009100.44483893
86GABAergic synapse_Homo sapiens_hsa047270.43986620
87Glutathione metabolism_Homo sapiens_hsa004800.43882678
88Phototransduction_Homo sapiens_hsa047440.42487915
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.42310907
90Caffeine metabolism_Homo sapiens_hsa002320.40934026
91HTLV-I infection_Homo sapiens_hsa051660.39892807
92Herpes simplex infection_Homo sapiens_hsa051680.39020504
93Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37458137
94Cardiac muscle contraction_Homo sapiens_hsa042600.36875837
95Synaptic vesicle cycle_Homo sapiens_hsa047210.35715983
96Legionellosis_Homo sapiens_hsa051340.35496478
97Vitamin B6 metabolism_Homo sapiens_hsa007500.34910082
98Basal cell carcinoma_Homo sapiens_hsa052170.34294001
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32673400
100Taste transduction_Homo sapiens_hsa047420.30809989
101Biosynthesis of amino acids_Homo sapiens_hsa012300.30408652
102Fatty acid degradation_Homo sapiens_hsa000710.29549620
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29272077
104Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.28597742
105Pentose phosphate pathway_Homo sapiens_hsa000300.26765382
106Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26604783
107Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.26195432
108Retinol metabolism_Homo sapiens_hsa008300.26055960
109Ether lipid metabolism_Homo sapiens_hsa005650.25815400
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.25309269
111Linoleic acid metabolism_Homo sapiens_hsa005910.24123423
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.23803060
113Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22938626
114Viral carcinogenesis_Homo sapiens_hsa052030.22710263
115Systemic lupus erythematosus_Homo sapiens_hsa053220.21168058
116Carbon metabolism_Homo sapiens_hsa012000.20367547
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.19370969
118Wnt signaling pathway_Homo sapiens_hsa043100.18615762
119Hedgehog signaling pathway_Homo sapiens_hsa043400.15427393
120alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12733786
121Serotonergic synapse_Homo sapiens_hsa047260.12633320
122Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.11989794
123Colorectal cancer_Homo sapiens_hsa052100.11797475
124Endometrial cancer_Homo sapiens_hsa052130.11340413
125Glucagon signaling pathway_Homo sapiens_hsa049220.10917806
126Glycosaminoglycan degradation_Homo sapiens_hsa005310.10579688
127Sphingolipid metabolism_Homo sapiens_hsa006000.10295984
128Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.10282075
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.10070711
130Cocaine addiction_Homo sapiens_hsa050300.09514505
131TGF-beta signaling pathway_Homo sapiens_hsa043500.07487492
132Pyruvate metabolism_Homo sapiens_hsa006200.07126381
133Prostate cancer_Homo sapiens_hsa052150.06163145
134Hippo signaling pathway_Homo sapiens_hsa043900.05308374

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