CFAP206

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1binding of sperm to zona pellucida (GO:0007339)9.89903135
2cell-cell recognition (GO:0009988)9.80709542
3acrosome reaction (GO:0007340)9.74709886
4motile cilium assembly (GO:0044458)9.40404378
5cilium movement (GO:0003341)9.24435131
6reproduction (GO:0000003)9.22886286
7piRNA metabolic process (GO:0034587)9.15627085
8spermatid development (GO:0007286)8.74360745
9regulation of cilium movement (GO:0003352)8.68759362
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.68642126
11male meiosis (GO:0007140)8.48499249
12synaptonemal complex organization (GO:0070193)7.66842538
13single fertilization (GO:0007338)7.55576006
14synaptonemal complex assembly (GO:0007130)7.42091258
15sperm capacitation (GO:0048240)6.67576604
16fertilization (GO:0009566)6.36467385
17ventricular system development (GO:0021591)6.36276548
18microtubule bundle formation (GO:0001578)5.93209614
19DNA methylation involved in gamete generation (GO:0043046)5.77626570
20spermatogenesis (GO:0007283)5.72480196
21male gamete generation (GO:0048232)5.70385430
22negative regulation of inclusion body assembly (GO:0090084)5.52834029
23male meiosis I (GO:0007141)5.49184007
24microtubule severing (GO:0051013)5.41411408
25gamete generation (GO:0007276)5.24888926
26chromosome organization involved in meiosis (GO:0070192)5.22883516
27organic cation transport (GO:0015695)5.19561975
28regulation of microtubule-based movement (GO:0060632)5.13770883
29cellular process involved in reproduction in multicellular organism (GO:0022412)5.10975661
30microtubule depolymerization (GO:0007019)5.07579095
31germ cell development (GO:0007281)5.02193428
32meiotic nuclear division (GO:0007126)4.86923821
33cell recognition (GO:0008037)4.76532142
34protein localization to cilium (GO:0061512)4.73544918
35primary alcohol catabolic process (GO:0034310)4.71768177
36seminiferous tubule development (GO:0072520)4.62742087
37regulation of inclusion body assembly (GO:0090083)4.56826171
38protein polyglutamylation (GO:0018095)4.54097627
39calcium ion-dependent exocytosis (GO:0017156)4.50227561
40retinal cone cell development (GO:0046549)4.48508916
41meiosis I (GO:0007127)4.40900883
42cell projection assembly (GO:0030031)4.34775284
43vitamin transmembrane transport (GO:0035461)4.17277908
44meiotic cell cycle (GO:0051321)4.16069412
45retinal rod cell development (GO:0046548)4.15923287
46multicellular organismal reproductive process (GO:0048609)4.13582665
47spermatid nucleus differentiation (GO:0007289)4.13261430
48diterpenoid biosynthetic process (GO:0016102)4.08513670
49genitalia morphogenesis (GO:0035112)4.03617442
50intraciliary transport (GO:0042073)4.02908021
51left/right pattern formation (GO:0060972)4.02337612
52monoubiquitinated protein deubiquitination (GO:0035520)4.01012638
53axoneme assembly (GO:0035082)3.87587613
54response to xenobiotic stimulus (GO:0009410)3.83410184
55ethanol metabolic process (GO:0006067)3.82811118
56photoreceptor cell maintenance (GO:0045494)3.81840731
57nonmotile primary cilium assembly (GO:0035058)3.75526963
58determination of left/right symmetry (GO:0007368)3.69593663
59smoothened signaling pathway (GO:0007224)3.55898038
60determination of bilateral symmetry (GO:0009855)3.54924328
61cilium organization (GO:0044782)3.46197775
62specification of symmetry (GO:0009799)3.45753074
63gene silencing by RNA (GO:0031047)3.44247273
64microtubule-based movement (GO:0007018)3.43807416
65nucleoside diphosphate phosphorylation (GO:0006165)3.42790070
66one-carbon compound transport (GO:0019755)3.40193410
67chaperone-mediated protein complex assembly (GO:0051131)3.38751687
68multicellular organismal development (GO:0007275)3.35653789
69pyrimidine-containing compound transmembrane transport (GO:0072531)3.34985240
70glycerol ether metabolic process (GO:0006662)3.34974301
71lateral ventricle development (GO:0021670)3.30666236
72cilium assembly (GO:0042384)3.30249323
73negative regulation of T cell differentiation in thymus (GO:0033085)3.28520469
74nuclear pore complex assembly (GO:0051292)3.28406954
75synapsis (GO:0007129)3.22384198
76chromosome condensation (GO:0030261)3.20470073
77cellular component assembly involved in morphogenesis (GO:0010927)3.20290989
78negative regulation of organelle assembly (GO:1902116)3.20198482
79centriole assembly (GO:0098534)3.19911213
80cilium morphogenesis (GO:0060271)3.16487861
81exogenous drug catabolic process (GO:0042738)3.15777402
82terpenoid biosynthetic process (GO:0016114)3.15505463
83neural tube formation (GO:0001841)3.12296414
84GTP biosynthetic process (GO:0006183)3.09779450
85lactate metabolic process (GO:0006089)3.09192897
86retinoic acid metabolic process (GO:0042573)3.09169051
87regulation of response to osmotic stress (GO:0047484)3.09105148
88ether metabolic process (GO:0018904)3.08660934
89meiotic cell cycle process (GO:1903046)3.08559632
90DNA packaging (GO:0006323)3.05368970
91centriole replication (GO:0007099)3.03695349
92lung epithelium development (GO:0060428)3.02983920
93regulation of centriole replication (GO:0046599)3.01439732
94cytoplasmic microtubule organization (GO:0031122)2.95391891
95negative regulation of humoral immune response (GO:0002921)2.93903459
96cornea development in camera-type eye (GO:0061303)2.92742040
97protein K11-linked deubiquitination (GO:0035871)2.92215054
98carnitine transport (GO:0015879)2.89816337
99amino-acid betaine transport (GO:0015838)2.89816337
100lateral sprouting from an epithelium (GO:0060601)2.88829182
101glomerular epithelial cell development (GO:0072310)2.87546556
102carnitine transmembrane transport (GO:1902603)2.86552673
103regulation of interleukin-5 production (GO:0032674)2.86132001
104glutathione derivative biosynthetic process (GO:1901687)2.85637927
105glutathione derivative metabolic process (GO:1901685)2.85637927
106ethanol oxidation (GO:0006069)2.83809811
107negative regulation of immunoglobulin mediated immune response (GO:0002890)2.82215519
108negative regulation of B cell mediated immunity (GO:0002713)2.82215519
109drug catabolic process (GO:0042737)2.79968871
110UTP biosynthetic process (GO:0006228)2.79842688
111glycolytic process (GO:0006096)2.79581723
112alditol metabolic process (GO:0019400)2.78910326
113regulation of collateral sprouting (GO:0048670)2.78496548
114organelle assembly (GO:0070925)2.77662456
115polyol catabolic process (GO:0046174)2.75778737
116tolerance induction (GO:0002507)2.75751254
117peptidyl-glutamic acid modification (GO:0018200)2.74099942
118sequestering of actin monomers (GO:0042989)2.70045182
119nucleus organization (GO:0006997)2.69720379
120microtubule-based process (GO:0007017)2.69257260
121regulation of spindle checkpoint (GO:0090231)2.69029048
122fucose catabolic process (GO:0019317)2.65875532
123L-fucose metabolic process (GO:0042354)2.65875532
124L-fucose catabolic process (GO:0042355)2.65875532
125spinal cord motor neuron differentiation (GO:0021522)2.65780278
126regulation of meiosis I (GO:0060631)2.65654712
127regulation of protein polyubiquitination (GO:1902914)2.65401531
128protein refolding (GO:0042026)2.64765885
129establishment of planar polarity (GO:0001736)2.62089444
130establishment of tissue polarity (GO:0007164)2.62089444
131photoreceptor cell development (GO:0042461)2.60053925
132establishment or maintenance of monopolar cell polarity (GO:0061339)2.55738942
133establishment of monopolar cell polarity (GO:0061162)2.55738942
134microtubule polymerization or depolymerization (GO:0031109)2.55229122
135pore complex assembly (GO:0046931)2.55014480
136nuclear pore organization (GO:0006999)2.54782126
137left/right axis specification (GO:0070986)2.53989881
138mitotic sister chromatid cohesion (GO:0007064)2.51483297
139eye photoreceptor cell development (GO:0042462)2.45269823
140aldehyde catabolic process (GO:0046185)2.43629616
141positive regulation of oligodendrocyte differentiation (GO:0048714)2.42497692
142retinol metabolic process (GO:0042572)2.42157779
143brain morphogenesis (GO:0048854)2.40762698
144positive regulation of smoothened signaling pathway (GO:0045880)2.35774348
145regulation of germinal center formation (GO:0002634)2.35283073
146benzene-containing compound metabolic process (GO:0042537)2.31695699
147establishment of apical/basal cell polarity (GO:0035089)2.31446853
148primary alcohol metabolic process (GO:0034308)2.31180526
149intra-S DNA damage checkpoint (GO:0031573)2.30751410
150heart looping (GO:0001947)2.24775639
151apical protein localization (GO:0045176)2.23736086
152carnitine metabolic process (GO:0009437)2.22269748
153limb development (GO:0060173)2.18518430
154appendage development (GO:0048736)2.18518430
155sialylation (GO:0097503)2.18157785
156response to pheromone (GO:0019236)2.17437172
157excretion (GO:0007588)2.17314439
158regulation of autophagic vacuole assembly (GO:2000785)2.14332171
159regulation of interleukin-13 production (GO:0032656)2.13657814
160cilium or flagellum-dependent cell motility (GO:0001539)14.1349829
161fusion of sperm to egg plasma membrane (GO:0007342)13.8486555
162acrosome assembly (GO:0001675)11.9201494
163sperm motility (GO:0030317)11.6897046
164multicellular organism reproduction (GO:0032504)11.3087857
165cell wall macromolecule metabolic process (GO:0044036)11.1082373
166cell wall macromolecule catabolic process (GO:0016998)11.1082373
167axonemal dynein complex assembly (GO:0070286)11.0991265
168sperm-egg recognition (GO:0035036)10.9841093
169plasma membrane fusion (GO:0045026)10.5204693
170epithelial cilium movement (GO:0003351)10.1239463

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.95852172
2EZH2_22144423_ChIP-Seq_EOC_Human4.62698954
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.46560633
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.31012564
5ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.66191366
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.64546696
7GBX2_23144817_ChIP-Seq_PC3_Human2.56589713
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.55430476
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.50347867
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.29360441
11PIAS1_25552417_ChIP-Seq_VCAP_Human2.22995841
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.20636380
13IGF1R_20145208_ChIP-Seq_DFB_Human2.14748436
14CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.07997106
15FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.05584048
16NR3C1_21868756_ChIP-Seq_MCF10A_Human2.03426722
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.00867999
18MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse11.0465535
19STAT6_21828071_ChIP-Seq_BEAS2B_Human1.99489778
20FUS_26573619_Chip-Seq_HEK293_Human1.96468981
21GATA1_26923725_Chip-Seq_HPCs_Mouse1.95854407
22TAF15_26573619_Chip-Seq_HEK293_Human1.94816811
23ELK4_26923725_Chip-Seq_MESODERM_Mouse1.91234307
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.89689199
25KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.89649925
26EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.89330953
27VDR_22108803_ChIP-Seq_LS180_Human1.89056173
28ZNF274_21170338_ChIP-Seq_K562_Hela1.87552988
29SMAD4_21799915_ChIP-Seq_A2780_Human1.86978799
30DROSHA_22980978_ChIP-Seq_HELA_Human1.84962465
31EWS_26573619_Chip-Seq_HEK293_Human1.83754012
32AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.78143263
33PCGF2_27294783_Chip-Seq_NPCs_Mouse1.76822611
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.75487026
35TOP2B_26459242_ChIP-Seq_MCF-7_Human1.74165213
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73988444
37P300_19829295_ChIP-Seq_ESCs_Human1.73882381
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.72315764
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66887459
40STAT3_23295773_ChIP-Seq_U87_Human1.66309832
41TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65431871
42AR_21572438_ChIP-Seq_LNCaP_Human1.64854522
43BCAT_22108803_ChIP-Seq_LS180_Human1.63868002
44KAP1_22055183_ChIP-Seq_ESCs_Mouse1.63606208
45RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.61941373
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.61596006
47SALL1_21062744_ChIP-ChIP_HESCs_Human1.61514055
48ER_23166858_ChIP-Seq_MCF-7_Human1.57267877
49FOXM1_26456572_ChIP-Seq_MCF-7_Human1.56921504
50AHR_22903824_ChIP-Seq_MCF-7_Human1.56123225
51RNF2_27304074_Chip-Seq_NSC_Mouse1.53059805
52SMAD3_21741376_ChIP-Seq_EPCs_Human1.51202693
53WDR5_24793694_ChIP-Seq_LNCAP_Human1.48787578
54STAT1_17558387_ChIP-Seq_HELA_Human1.46433714
55GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.46383855
56FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45971096
57TCF4_22108803_ChIP-Seq_LS180_Human1.45506916
58TCF4_23295773_ChIP-Seq_U87_Human1.44886413
59ARNT_22903824_ChIP-Seq_MCF-7_Human1.44248734
60TAL1_26923725_Chip-Seq_HPCs_Mouse1.43599056
61SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40532908
62GATA3_21867929_ChIP-Seq_CD8_Mouse1.39658991
63MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.39370891
64AR_25329375_ChIP-Seq_VCAP_Human1.37471935
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36530341
66CBP_20019798_ChIP-Seq_JUKART_Human1.36530341
67NFE2_27457419_Chip-Seq_LIVER_Mouse1.35329826
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.34850811
69BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33652869
70SUZ12_27294783_Chip-Seq_NPCs_Mouse1.30850070
71RUNX2_22187159_ChIP-Seq_PCA_Human1.30682115
72SOX2_22085726_ChIP-Seq_NPCs_Mouse1.30376586
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29282712
74SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.28187024
75SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.28111244
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27822059
77SMAD4_21741376_ChIP-Seq_EPCs_Human1.27633361
78FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26625659
79FOXA1_25329375_ChIP-Seq_VCAP_Human1.26625659
80KDM2B_26808549_Chip-Seq_REH_Human1.25685058
81ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.25672451
82ESR1_20079471_ChIP-ChIP_T-47D_Human1.24931454
83TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21878654
84GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20435661
85KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20181153
86REST_21632747_ChIP-Seq_MESCs_Mouse1.18989615
87NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18818407
88LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.18633278
89ETV1_20927104_ChIP-Seq_GIST48_Human1.18617073
90SOX2_19829295_ChIP-Seq_ESCs_Human1.17501411
91NANOG_19829295_ChIP-Seq_ESCs_Human1.17501411
92GATA3_21867929_ChIP-Seq_TH1_Mouse1.17446914
93ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17445370
94FLI1_21867929_ChIP-Seq_TH2_Mouse1.16863374
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16268428
96RUNX1_26923725_Chip-Seq_HPCs_Mouse1.16182894
97PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.15346400
98AR_20517297_ChIP-Seq_VCAP_Human1.14588519
99CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13833445
100OCT4_18555785_Chip-Seq_ESCs_Mouse1.13072869
101MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.13033363
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12278185
103TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.12211257
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11969249
105TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11969249
106TP53_18474530_ChIP-ChIP_U2OS_Human1.11866128
107PHF8_20622853_ChIP-Seq_HELA_Human1.11257086
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.10826522
109GF1_26923725_Chip-Seq_HPCs_Mouse1.10167674
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.09072134
111CDX2_22108803_ChIP-Seq_LS180_Human1.09053087
112TBL1_22424771_ChIP-Seq_293T_Human1.08616396
113NANOG_18555785_Chip-Seq_ESCs_Mouse1.07832430
114FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07320955
115PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06468825
116ESET_19884257_ChIP-Seq_ESCs_Mouse1.06405878
117EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06247186
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05440848
119OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05333438
120FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05064195
121SPI1_26923725_Chip-Seq_HPCs_Mouse1.04935974
122P53_21459846_ChIP-Seq_SAOS-2_Human1.04683673
123TP63_23658742_ChIP-Seq_EP156T_Human1.04132633
124TP53_16413492_ChIP-PET_HCT116_Human1.02953010
125NFYB_21822215_ChIP-Seq_K562_Human1.02843362
126CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.02776418
127KLF4_18555785_Chip-Seq_ESCs_Mouse1.02749616
128GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02580325
129PRDM14_20953172_ChIP-Seq_ESCs_Human1.02387430
130ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01387668
131NFYA_21822215_ChIP-Seq_K562_Human1.01349629
132ZFP57_27257070_Chip-Seq_ESCs_Mouse1.01142035
133P300_18555785_Chip-Seq_ESCs_Mouse1.00399026
134FOXA1_25552417_ChIP-Seq_VCAP_Human1.00312968
135CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00293765
136RBPJ_21746931_ChIP-Seq_IB4_Human0.99948232
137AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.99824026
138CRX_20693478_ChIP-Seq_RETINA_Mouse0.99565094
139SMRT_27268052_Chip-Seq_Bcells_Human0.99418623
140YY1_22570637_ChIP-Seq_MALME-3M_Human0.99071365
141ERG_20517297_ChIP-Seq_VCAP_Human0.98980569
142STAT3_18555785_ChIP-Seq_MESCs_Mouse0.98547782
143CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97800752
144CMYC_18555785_Chip-Seq_ESCs_Mouse0.97755772
145P53_22387025_ChIP-Seq_ESCs_Mouse0.96897072
146MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96890498
147EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95786587
148EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95691368
149PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95356545
150RAD21_21589869_ChIP-Seq_MESCs_Mouse0.95137179
151RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95023126
152PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93640635
153STAT3_18555785_Chip-Seq_ESCs_Mouse0.92830692
154CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92333505
155NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.90176747
156SUZ12_18555785_Chip-Seq_ESCs_Mouse0.89987573
157SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89821639
158CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.87926047
159CTCF_18555785_Chip-Seq_ESCs_Mouse0.87838201
160GF1B_26923725_Chip-Seq_HPCs_Mouse0.87784234
161RUNX1_27457419_Chip-Seq_LIVER_Mouse0.87705282
162OCT4_21477851_ChIP-Seq_ESCs_Mouse0.87560342
163EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.87473184
164RARA_24833708_ChIP-Seq_LIVER_Mouse0.87370391
165EZH2_27294783_Chip-Seq_NPCs_Mouse0.86876830
166LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.86393485
167MYC_27129775_Chip-Seq_CORNEA_Mouse0.86167889
168RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86032838

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.85929396
2MP0001929_abnormal_gametogenesis5.37073579
3MP0008877_abnormal_DNA_methylation4.77237488
4MP0008875_abnormal_xenobiotic_pharmacok4.73792168
5MP0002653_abnormal_ependyma_morphology4.09322971
6MP0002210_abnormal_sex_determination3.67365619
7MP0002161_abnormal_fertility/fecundity3.14722300
8MP0001145_abnormal_male_reproductive3.14499609
9MP0000653_abnormal_sex_gland2.69222173
10MP0005623_abnormal_meninges_morphology2.44259861
11MP0000383_abnormal_hair_follicle2.44248638
12MP0002277_abnormal_respiratory_mucosa2.32642528
13MP0009780_abnormal_chondrocyte_physiolo2.27035081
14MP0008057_abnormal_DNA_replication2.15771964
15MP0000566_synostosis2.06029722
16MP0005410_abnormal_fertilization14.8325988
17MP0002160_abnormal_reproductive_system1.98007851
18MP0003011_delayed_dark_adaptation1.89782244
19MP0010678_abnormal_skin_adnexa1.89726572
20MP0003136_yellow_coat_color1.88579090
21MP0001984_abnormal_olfaction1.85159511
22MP0002638_abnormal_pupillary_reflex1.76031541
23MP0002909_abnormal_adrenal_gland1.67521057
24MP0005645_abnormal_hypothalamus_physiol1.61163833
25MP0003195_calcinosis1.54588118
26MP0002734_abnormal_mechanical_nocicepti1.53209483
27MP0002735_abnormal_chemical_nociception1.52121903
28MP0005670_abnormal_white_adipose1.50594948
29MP0005646_abnormal_pituitary_gland1.43138885
30MP0009046_muscle_twitch1.43137917
31MP0002282_abnormal_trachea_morphology1.40972566
32MP0002876_abnormal_thyroid_physiology1.40826772
33MP0001485_abnormal_pinna_reflex1.37200673
34MP0000631_abnormal_neuroendocrine_gland1.36245517
35MP0003880_abnormal_central_pattern1.35350025
36MP0008058_abnormal_DNA_repair1.33557757
37MP0005248_abnormal_Harderian_gland1.27562402
38MP0009745_abnormal_behavioral_response1.22300487
39MP0006276_abnormal_autonomic_nervous1.19718991
40MP0001346_abnormal_lacrimal_gland1.18915211
41MP0002168_other_aberrant_phenotype1.16689298
42MP0001502_abnormal_circadian_rhythm1.13715250
43MP0005083_abnormal_biliary_tract1.13377183
44MP0002557_abnormal_social/conspecific_i1.12630228
45MP0001529_abnormal_vocalization1.12409154
46MP0005647_abnormal_sex_gland1.11920350
47MP0000026_abnormal_inner_ear1.09361831
48MP0002272_abnormal_nervous_system1.06474443
49MP0001970_abnormal_pain_threshold1.06248935
50MP0003937_abnormal_limbs/digits/tail_de1.06109291
51MP0008872_abnormal_physiological_respon1.05460438
52MP0001486_abnormal_startle_reflex1.04993615
53MP0003646_muscle_fatigue1.04976688
54MP0005389_reproductive_system_phenotype1.04276431
55MP0010386_abnormal_urinary_bladder1.03876237
56MP0005395_other_phenotype1.02942315
57MP0002572_abnormal_emotion/affect_behav1.00934320
58MP0003718_maternal_effect1.00874156
59MP0010094_abnormal_chromosome_stability1.00573283
60MP0008995_early_reproductive_senescence0.97269605
61MP0004142_abnormal_muscle_tone0.95739844
62MP0001765_abnormal_ion_homeostasis0.93347390
63MP0003786_premature_aging0.93124460
64MP0001968_abnormal_touch/_nociception0.90738371
65MP0004885_abnormal_endolymph0.90326290
66MP0000049_abnormal_middle_ear0.89038188
67MP0004233_abnormal_muscle_weight0.88959436
68MP0002229_neurodegeneration0.86251576
69MP0001293_anophthalmia0.86063215
70MP0001963_abnormal_hearing_physiology0.84322056
71MP0000372_irregular_coat_pigmentation0.84283739
72MP0003938_abnormal_ear_development0.83783856
73MP0010030_abnormal_orbit_morphology0.83297074
74MP0000955_abnormal_spinal_cord0.82421358
75MP0005187_abnormal_penis_morphology0.79140409
76MP0005394_taste/olfaction_phenotype0.78148958
77MP0005499_abnormal_olfactory_system0.78148958
78MP0004264_abnormal_extraembryonic_tissu0.78017096
79MP0003656_abnormal_erythrocyte_physiolo0.75299754
80MP0005365_abnormal_bile_salt0.73217265
81MP0008007_abnormal_cellular_replicative0.72690555
82MP0005408_hypopigmentation0.72622745
83MP0003890_abnormal_embryonic-extraembry0.71099565
84MP0005220_abnormal_exocrine_pancreas0.71046278
85MP0005085_abnormal_gallbladder_physiolo0.70788072
86MP0002928_abnormal_bile_duct0.69987469
87MP0002736_abnormal_nociception_after0.69697739
88MP0001919_abnormal_reproductive_system0.69522671
89MP0000778_abnormal_nervous_system0.69270568
90MP0001905_abnormal_dopamine_level0.68928608
91MP0000358_abnormal_cell_content/0.68740509
92MP0002882_abnormal_neuron_morphology0.68435771
93MP0002067_abnormal_sensory_capabilities0.67906415
94MP0002184_abnormal_innervation0.67866909
95MP0004147_increased_porphyrin_level0.67858526
96MP0004133_heterotaxia0.65131237
97MP0005253_abnormal_eye_physiology0.61030392
98MP0001324_abnormal_eye_pigmentation0.58003708
99MP0005391_vision/eye_phenotype0.57988468
100MP0003950_abnormal_plasma_membrane0.57628293
101MP0006035_abnormal_mitochondrial_morpho0.57490126
102MP0002234_abnormal_pharynx_morphology0.57080849
103MP0003878_abnormal_ear_physiology0.56131906
104MP0005377_hearing/vestibular/ear_phenot0.56131906
105MP0002132_abnormal_respiratory_system0.53942620
106MP0002102_abnormal_ear_morphology0.51721157
107MP0002092_abnormal_eye_morphology0.50159880
108MP0005551_abnormal_eye_electrophysiolog0.49950145
109MP0004134_abnormal_chest_morphology0.49500895
110MP0001545_abnormal_hematopoietic_system0.46987328
111MP0005397_hematopoietic_system_phenotyp0.46987328
112MP0003699_abnormal_female_reproductive0.46927683
113MP0001119_abnormal_female_reproductive0.43761018
114MP0003115_abnormal_respiratory_system0.43215292
115MP0003861_abnormal_nervous_system0.42343019
116MP0008961_abnormal_basal_metabolism0.41778635
117MP0001672_abnormal_embryogenesis/_devel0.41620441
118MP0005380_embryogenesis_phenotype0.41620441
119MP0003111_abnormal_nucleus_morphology0.41609994
120MP0002084_abnormal_developmental_patter0.40559958
121MP0005075_abnormal_melanosome_morpholog0.40253567
122MP0005636_abnormal_mineral_homeostasis0.38436441
123MP0001730_embryonic_growth_arrest0.37518125
124MP0000432_abnormal_head_morphology0.37132751
125MP0000427_abnormal_hair_cycle0.36922919
126MP0000313_abnormal_cell_death0.36896811
127MP0002233_abnormal_nose_morphology0.36500405
128MP0000569_abnormal_digit_pigmentation0.36189867
129MP0006036_abnormal_mitochondrial_physio0.36042649
130MP0003984_embryonic_growth_retardation0.35539793
131MP0003183_abnormal_peptide_metabolism0.35178638
132MP0002254_reproductive_system_inflammat0.34609811
133MP0004019_abnormal_vitamin_homeostasis0.34087069
134MP0002088_abnormal_embryonic_growth/wei0.33929450
135MP0003077_abnormal_cell_cycle0.33656938
136MP0009115_abnormal_fat_cell0.32832754
137MP0004808_abnormal_hematopoietic_stem0.32751884
138MP0002269_muscular_atrophy0.32534776
139MP0004858_abnormal_nervous_system0.32072156
140MP0001849_ear_inflammation0.31532935
141MP0005266_abnormal_metabolism0.31277964
142MP0004043_abnormal_pH_regulation0.30684836
143MP0002085_abnormal_embryonic_tissue0.30548297
144MP0003942_abnormal_urinary_system0.27974183
145MP0002152_abnormal_brain_morphology0.27559849
146MP0002970_abnormal_white_adipose0.26092614
147MP0002114_abnormal_axial_skeleton0.26086623
148MP0006072_abnormal_retinal_apoptosis0.25653715
149MP0010307_abnormal_tumor_latency0.25402408
150MP0005666_abnormal_adipose_tissue0.25386664
151MP0005195_abnormal_posterior_eye0.25181459
152MP0001727_abnormal_embryo_implantation0.25106857
153MP0000534_abnormal_ureter_morphology0.24925755
154MP0000647_abnormal_sebaceous_gland0.24622895
155MP0003787_abnormal_imprinting0.24281042
156MP0002116_abnormal_craniofacial_bone0.23570777
157MP0008789_abnormal_olfactory_epithelium0.23040921
158MP0002332_abnormal_exercise_endurance0.22900804
159MP0002752_abnormal_somatic_nervous0.22506524
160MP0004036_abnormal_muscle_relaxation0.22036074
161MP0003633_abnormal_nervous_system0.21792926

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.93300896
2Abnormal respiratory epithelium morphology (HP:0012253)8.75709050
3Abnormal respiratory motile cilium morphology (HP:0005938)8.75709050
4Abnormal ciliary motility (HP:0012262)8.39506520
5Rhinitis (HP:0012384)8.16958031
6Chronic bronchitis (HP:0004469)7.52791040
7Nasal polyposis (HP:0100582)6.58466675
8Infertility (HP:0000789)5.87450240
9Abnormality of the nasal mucosa (HP:0000433)5.42264434
10Bronchiectasis (HP:0002110)4.76009158
11Bronchitis (HP:0012387)4.49162706
12Nephronophthisis (HP:0000090)4.23844968
13Pancreatic cysts (HP:0001737)3.86073983
14Chronic hepatic failure (HP:0100626)3.74833592
15Abnormality of the lower motor neuron (HP:0002366)3.60280882
16Recurrent sinusitis (HP:0011108)3.47141764
17Male infertility (HP:0003251)3.23989762
18Abnormality of the renal medulla (HP:0100957)3.21953177
19Recurrent otitis media (HP:0000403)3.19591400
20Molar tooth sign on MRI (HP:0002419)3.07595981
21Abnormality of midbrain morphology (HP:0002418)3.07595981
22Medial flaring of the eyebrow (HP:0010747)2.86893317
23Tubulointerstitial nephritis (HP:0001970)2.74998061
24Absent rod-and cone-mediated responses on ERG (HP:0007688)2.71660122
25Amyotrophic lateral sclerosis (HP:0007354)2.68266605
26Abnormal spermatogenesis (HP:0008669)2.62227058
27Hyperactive renin-angiotensin system (HP:0000841)2.51755812
28Impulsivity (HP:0100710)2.49787605
29Recurrent bronchitis (HP:0002837)2.46743817
30Anencephaly (HP:0002323)2.42185680
31Tubular atrophy (HP:0000092)2.40157687
32Tubulointerstitial abnormality (HP:0001969)2.29935579
33Fibular hypoplasia (HP:0003038)2.28752057
34Gonadotropin excess (HP:0000837)2.28652887
35Chronic otitis media (HP:0000389)2.28174991
36Male pseudohermaphroditism (HP:0000037)2.26275985
37Postaxial foot polydactyly (HP:0001830)2.23053726
38Sclerocornea (HP:0000647)2.19118254
39Decreased circulating renin level (HP:0003351)2.15720333
40Congenital hepatic fibrosis (HP:0002612)2.08823701
41Abnormal rod and cone electroretinograms (HP:0008323)2.08610522
42Atelectasis (HP:0100750)2.05178943
43Facial cleft (HP:0002006)2.04807433
44Furrowed tongue (HP:0000221)2.04527181
45Supernumerary spleens (HP:0009799)2.01798362
46Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.8517073
47Dynein arm defect of respiratory motile cilia (HP:0012255)12.1252027
48Absent/shortened dynein arms (HP:0200106)12.1252027
49Impaired proprioception (HP:0010831)1.96754384
50Azoospermia (HP:0000027)1.95665124
51Absent frontal sinuses (HP:0002688)1.91227343
52Oculomotor apraxia (HP:0000657)1.88391770
53Congenital primary aphakia (HP:0007707)1.87560623
54Gait imbalance (HP:0002141)1.87470232
55Upper motor neuron abnormality (HP:0002127)1.87380879
56Tubulointerstitial fibrosis (HP:0005576)1.84482621
57Postaxial hand polydactyly (HP:0001162)1.82898308
58Abnormality of permanent molar morphology (HP:0011071)1.82501043
59Abnormality of the dental root (HP:0006486)1.82501043
60Taurodontia (HP:0000679)1.82501043
61Abnormal biliary tract physiology (HP:0012439)1.82497333
62Bile duct proliferation (HP:0001408)1.82497333
63Pancreatic fibrosis (HP:0100732)1.79719060
64Preaxial hand polydactyly (HP:0001177)1.79685688
65Stage 5 chronic kidney disease (HP:0003774)1.77843464
66Chronic sinusitis (HP:0011109)1.77711082
67Abnormality of dentin (HP:0010299)1.75050786
68Aplasia/Hypoplasia of the spleen (HP:0010451)1.74453332
69Short ribs (HP:0000773)1.72957217
70Abnormality of molar (HP:0011077)1.69590979
71Abnormality of molar morphology (HP:0011070)1.69590979
72Asplenia (HP:0001746)1.67311477
73Hypoplasia of the capital femoral epiphysis (HP:0003090)1.66865999
74Renal salt wasting (HP:0000127)1.66125056
75Microglossia (HP:0000171)1.65792685
76Cystic liver disease (HP:0006706)1.65509556
77Abnormality of the dental pulp (HP:0006479)1.64535179
78Dyschromatopsia (HP:0007641)1.62455026
79Abnormality of the renal cortex (HP:0011035)1.61093700
80Renal dysplasia (HP:0000110)1.60011743
81Nephrogenic diabetes insipidus (HP:0009806)1.59794430
82Aplasia/Hypoplasia of the tongue (HP:0010295)1.59319205
83Spastic tetraparesis (HP:0001285)1.59216840
84Median cleft lip (HP:0000161)1.58518280
85Hyperaldosteronism (HP:0000859)1.58316521
86Abnormal drinking behavior (HP:0030082)1.57648278
87Polydipsia (HP:0001959)1.57648278
88Narrow forehead (HP:0000341)1.53392106
89Nephroblastoma (Wilms tumor) (HP:0002667)1.53235905
90J-shaped sella turcica (HP:0002680)1.52266872
91Bifid tongue (HP:0010297)1.51242051
92Bony spicule pigmentary retinopathy (HP:0007737)1.50854010
93True hermaphroditism (HP:0010459)1.49634250
94Hyperkalemia (HP:0002153)1.47073739
95Abnormality of the anterior horn cell (HP:0006802)1.46919878
96Degeneration of anterior horn cells (HP:0002398)1.46919878
97Heterotopia (HP:0002282)1.45572232
98Retinitis pigmentosa (HP:0000510)1.45463413
99Aplasia/Hypoplasia of the fibula (HP:0006492)1.41593522
100Poor coordination (HP:0002370)1.41500330
101Embryonal renal neoplasm (HP:0011794)1.41254014
102Abnormality of renal excretion (HP:0011036)1.41249179
103Absent speech (HP:0001344)1.41145222
104Short thorax (HP:0010306)1.40249625
105Genital tract atresia (HP:0001827)1.40007414
106Aplasia/Hypoplasia of the lens (HP:0008063)1.39959477
107Prominent nasal bridge (HP:0000426)1.38720232
108Abnormality of renin-angiotensin system (HP:0000847)1.38263240
109Polyuria (HP:0000103)1.37775965
110Vaginal atresia (HP:0000148)1.35797109
11111 pairs of ribs (HP:0000878)1.35723923
112Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.35391796
113Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.35383529
114Aganglionic megacolon (HP:0002251)1.34968348
115Hypokalemic alkalosis (HP:0001949)1.34529122
116Abnormality of macular pigmentation (HP:0008002)1.33045897
117Tongue fasciculations (HP:0001308)1.32574293
118Cone-rod dystrophy (HP:0000548)1.31082625
119Constricted visual fields (HP:0001133)1.30068928
120Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.29479420
121Absent epiphyses (HP:0010577)1.29479420
122Highly arched eyebrow (HP:0002553)1.29463073
123Multicystic kidney dysplasia (HP:0000003)1.29092884
124Bell-shaped thorax (HP:0001591)1.28137833
125Abnormality of ocular smooth pursuit (HP:0000617)1.27986830
126Broad foot (HP:0001769)1.24853672
127Nephropathy (HP:0000112)1.23856947
128Abnormality of chloride homeostasis (HP:0011422)1.23738129
129Sloping forehead (HP:0000340)1.21656051
130Decreased central vision (HP:0007663)1.20317923
131Occipital encephalocele (HP:0002085)1.19910582
132Deformed sella turcica (HP:0002681)1.19279297
133Cholecystitis (HP:0001082)1.19171520
134Abnormal gallbladder physiology (HP:0012438)1.19171520
135Hip dysplasia (HP:0001385)1.16637352
136Decreased testicular size (HP:0008734)1.15708084
137Type II lissencephaly (HP:0007260)1.15506700
138Specific learning disability (HP:0001328)1.15353782
139Abolished electroretinogram (ERG) (HP:0000550)1.11388710
140Chorioretinal coloboma (HP:0000567)1.09247376
141Abnormal urine output (HP:0012590)1.08654106
142Intellectual disability, moderate (HP:0002342)1.06884931

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.89862263
2PDK38.89862263
3PDK25.76360261
4MST44.22655079
5TESK14.18776617
6FRK3.41889418
7PRKD33.36192694
8ICK2.94584088
9BCR2.78713108
10MAP4K22.49617079
11TRIM282.45659707
12CASK2.38241335
13WNK42.35307511
14PTK2B2.35224974
15STK392.30995401
16PNCK2.27395335
17MARK11.98798043
18EPHA21.85744018
19NEK21.83387877
20CDK121.81567177
21INSRR1.66693894
22TNIK1.66542628
23MAPK131.66252730
24BMPR1B1.52340108
25MAPKAPK31.49275829
26STK381.42044501
27WNK11.40714381
28TYRO31.37942888
29TLK11.33247560
30STK161.32116307
31MAP3K21.18028856
32MAPK151.15423846
33TTK1.13479229
34ERBB31.11212068
35ACVR1B1.08428027
36EPHA41.07407848
37GRK51.02798638
38FER0.97577625
39EPHA30.97319985
40DYRK1B0.96169273
41STK240.94701451
42NME10.92350768
43MAP3K120.92247571
44PDK10.90608032
45PRKCI0.88564305
46NTRK30.86661209
47STK30.83790845
48PRKCE0.80160132
49MAP3K90.79407987
50DYRK30.78828893
51OXSR10.78573583
52LMTK20.75930524
53CHEK20.74162736
54NLK0.73806932
55PAK30.73551584
56CAMKK20.71475163
57CSNK1G20.70989917
58DYRK20.70104724
59WEE10.69929496
60GRK10.68412311
61CCNB10.67386163
62CDC70.66627876
63ERBB20.63696131
64STK38L0.59600888
65PASK0.59264231
66CHEK10.59250680
67CSNK1A1L0.58624289
68LIMK10.57528591
69IRAK10.57292102
70PLK20.56691956
71GRK60.53635062
72CAMK2A0.53100504
73WNK30.52718494
74DYRK1A0.52437552
75ZAK0.52111629
76MAP2K60.50138007
77CSF1R0.49665716
78KSR10.49521488
79PINK10.47609757
80NUAK10.47485381
81CSNK1G10.47246813
82MKNK20.47161527
83ERN10.47088387
84ADRBK20.47056637
85STK100.46691539
86CSNK1G30.46475814
87VRK10.46396520
88CAMK1G0.46091886
89FGFR20.45622505
90PLK40.44424800
91MINK10.43889424
92PRKACA0.43851128
93BCKDK0.43485583
94PLK10.42153272
95MARK20.41620485
96ATR0.40314068
97SGK20.38088279
98ATM0.38009307
99NTRK20.37178624
100TESK20.36885437
101TRPM70.36080204
102TGFBR20.35947434
103GRK70.34525056
104DAPK20.34185540
105EIF2AK30.32331666
106PRKCG0.32060522
107MTOR0.31187175
108PAK10.30342176
109PRKG20.29848142
110ABL10.29493778
111EEF2K0.28598474
112MAP3K70.28417691
113PRKCA0.27978789
114PDPK10.27860869
115MAP3K100.26955335
116SIK30.26918521
117SGK2230.26337661
118SGK4940.26337661
119BRSK20.24777807
120TAF10.24333313
121PRKAA10.23266609
122RPS6KA50.23261915
123PKN10.22382869
124CSNK1A10.21899659
125SGK10.21890641
126MAPK70.21165754
127PAK40.19590269
128IRAK20.15436675
129CAMKK10.13576429
130MATK0.13345152
131PAK20.12964062
132RPS6KB10.11762383
133RIPK10.10478006
134CDK20.09851141
135MOS0.09756884
136PRKACG0.08945287
137AURKA0.08893705
138CDK10.08809918
139GSK3B0.07605017
140MUSK0.07470632
141CDK150.07263497
142NEK60.07103443
143MAPKAPK50.05879413
144MAP3K40.05485467
145PRKCQ0.05449882
146BRSK10.05157572
147CDK70.05040744
148MAPK100.05009120
149CDK180.04950828
150MAPK80.04775988
151CSK0.04652097
152PRKG10.04448408
153MAP2K40.04284463
154CSNK1D0.04061714
155CSNK2A10.04021135
156CDK11A0.03678120
157PRKACB0.03651623
158MAP2K70.03421410
159MARK30.03300177
160BRAF0.02399904
161PRKCZ0.01950683
162ADRBK10.01831843
163RIPK40.01229865
164AKT30.01166094
165ZAP700.00590935
166CDK140.00533562

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007506.11223536
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.07674394
3Pyruvate metabolism_Homo sapiens_hsa006203.93012116
4Histidine metabolism_Homo sapiens_hsa003403.24754439
5Propanoate metabolism_Homo sapiens_hsa006402.99922446
6Fatty acid biosynthesis_Homo sapiens_hsa000612.88979700
7Basal transcription factors_Homo sapiens_hsa030222.78913697
8Pentose phosphate pathway_Homo sapiens_hsa000302.67697688
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.67427479
10Linoleic acid metabolism_Homo sapiens_hsa005912.62223913
11Glucagon signaling pathway_Homo sapiens_hsa049222.61988814
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.55578907
13beta-Alanine metabolism_Homo sapiens_hsa004102.54454989
14Fanconi anemia pathway_Homo sapiens_hsa034602.47561609
15Phenylalanine metabolism_Homo sapiens_hsa003602.42426929
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.25415879
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.24876407
18Caffeine metabolism_Homo sapiens_hsa002322.22584447
19Tyrosine metabolism_Homo sapiens_hsa003502.19206249
20Dorso-ventral axis formation_Homo sapiens_hsa043202.12190176
21Selenocompound metabolism_Homo sapiens_hsa004502.08476976
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.92049664
23Oocyte meiosis_Homo sapiens_hsa041141.91288032
24Fructose and mannose metabolism_Homo sapiens_hsa000511.89373263
25Butanoate metabolism_Homo sapiens_hsa006501.84133001
26Glycerolipid metabolism_Homo sapiens_hsa005611.82081672
27Huntingtons disease_Homo sapiens_hsa050161.72630948
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.70322074
29Steroid hormone biosynthesis_Homo sapiens_hsa001401.69921806
30Nitrogen metabolism_Homo sapiens_hsa009101.66833938
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.66439007
32Nicotine addiction_Homo sapiens_hsa050331.64221357
33Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.62922405
34Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.61510848
35Phototransduction_Homo sapiens_hsa047441.59712393
36Peroxisome_Homo sapiens_hsa041461.56788778
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.44373946
38PPAR signaling pathway_Homo sapiens_hsa033201.43968803
39Glycerophospholipid metabolism_Homo sapiens_hsa005641.42311581
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.41120043
41mRNA surveillance pathway_Homo sapiens_hsa030151.39812743
42Amphetamine addiction_Homo sapiens_hsa050311.37635238
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.37247553
44Tryptophan metabolism_Homo sapiens_hsa003801.35117609
45Carbohydrate digestion and absorption_Homo sapiens_hsa049731.34247153
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.33964853
47Carbon metabolism_Homo sapiens_hsa012001.33347268
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.30088385
49Renin secretion_Homo sapiens_hsa049241.27258446
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27142992
51RNA transport_Homo sapiens_hsa030131.25752494
52Maturity onset diabetes of the young_Homo sapiens_hsa049501.25379739
53Oxidative phosphorylation_Homo sapiens_hsa001901.25098281
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23657914
55Ether lipid metabolism_Homo sapiens_hsa005651.23179722
56Circadian rhythm_Homo sapiens_hsa047101.22891738
57Sphingolipid metabolism_Homo sapiens_hsa006001.21984756
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19863520
59Arachidonic acid metabolism_Homo sapiens_hsa005901.15651850
60Cardiac muscle contraction_Homo sapiens_hsa042601.15061417
61Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.11066491
62Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10956107
63Protein export_Homo sapiens_hsa030601.09353684
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.08247857
65Steroid biosynthesis_Homo sapiens_hsa001001.04222957
66Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.02863846
67Mineral absorption_Homo sapiens_hsa049780.95856112
68Regulation of autophagy_Homo sapiens_hsa041400.94913894
69Purine metabolism_Homo sapiens_hsa002300.92979048
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.92151498
71Biosynthesis of amino acids_Homo sapiens_hsa012300.86041122
72Chemical carcinogenesis_Homo sapiens_hsa052040.85057545
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.82293885
74Renin-angiotensin system_Homo sapiens_hsa046140.82022460
75Tight junction_Homo sapiens_hsa045300.81625122
76Fat digestion and absorption_Homo sapiens_hsa049750.80708457
77Antigen processing and presentation_Homo sapiens_hsa046120.79587830
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78891879
79Long-term potentiation_Homo sapiens_hsa047200.76560277
80Parkinsons disease_Homo sapiens_hsa050120.74233145
81Olfactory transduction_Homo sapiens_hsa047400.72597412
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.71811571
83Serotonergic synapse_Homo sapiens_hsa047260.71022476
84Taste transduction_Homo sapiens_hsa047420.70294540
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69556882
86Glutathione metabolism_Homo sapiens_hsa004800.67437434
87ABC transporters_Homo sapiens_hsa020100.66613553
88Calcium signaling pathway_Homo sapiens_hsa040200.66574160
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66312374
90Inositol phosphate metabolism_Homo sapiens_hsa005620.65760420
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.65135258
92Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.63851097
93Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.61470837
94Cocaine addiction_Homo sapiens_hsa050300.61262287
95Fatty acid metabolism_Homo sapiens_hsa012120.60271518
96AMPK signaling pathway_Homo sapiens_hsa041520.58690590
97Hedgehog signaling pathway_Homo sapiens_hsa043400.58127399
98Pentose and glucuronate interconversions_Homo sapiens_hsa000400.57840527
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57478439
100Estrogen signaling pathway_Homo sapiens_hsa049150.57217916
101Fatty acid degradation_Homo sapiens_hsa000710.55846939
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55428608
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54962879
104Alzheimers disease_Homo sapiens_hsa050100.54316969
105GABAergic synapse_Homo sapiens_hsa047270.54243964
106Morphine addiction_Homo sapiens_hsa050320.53701720
107Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.53391138
108Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53300888
109Starch and sucrose metabolism_Homo sapiens_hsa005000.47725701
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.47661827
111VEGF signaling pathway_Homo sapiens_hsa043700.44061227
112Axon guidance_Homo sapiens_hsa043600.43673709
113Adipocytokine signaling pathway_Homo sapiens_hsa049200.43273294
114Insulin secretion_Homo sapiens_hsa049110.43063765
115Collecting duct acid secretion_Homo sapiens_hsa049660.41268386
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39586953
117Bile secretion_Homo sapiens_hsa049760.39097420
118Thyroid hormone synthesis_Homo sapiens_hsa049180.38562262
119Cell cycle_Homo sapiens_hsa041100.38094473
120Homologous recombination_Homo sapiens_hsa034400.37720927
121Metabolic pathways_Homo sapiens_hsa011000.37325762
122Arginine and proline metabolism_Homo sapiens_hsa003300.37310390
123RNA degradation_Homo sapiens_hsa030180.36853722
124Endocytosis_Homo sapiens_hsa041440.36722516
125Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.36488267
126Hippo signaling pathway_Homo sapiens_hsa043900.36419753
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33501935
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33273733
129Vascular smooth muscle contraction_Homo sapiens_hsa042700.32518374
130Protein digestion and absorption_Homo sapiens_hsa049740.32278618
131cAMP signaling pathway_Homo sapiens_hsa040240.31803585
132Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31438780
133N-Glycan biosynthesis_Homo sapiens_hsa005100.30130238
134Systemic lupus erythematosus_Homo sapiens_hsa053220.29675293
135Dopaminergic synapse_Homo sapiens_hsa047280.28654463
136Retinol metabolism_Homo sapiens_hsa008300.26518201
137Wnt signaling pathway_Homo sapiens_hsa043100.26349688
138Salivary secretion_Homo sapiens_hsa049700.26183686
139Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.25235573
140Ovarian steroidogenesis_Homo sapiens_hsa049130.24781577
141Synaptic vesicle cycle_Homo sapiens_hsa047210.22635203
142Nucleotide excision repair_Homo sapiens_hsa034200.22107712
143Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.21882072
144Glutamatergic synapse_Homo sapiens_hsa047240.21772798
145Legionellosis_Homo sapiens_hsa051340.20519110
146Circadian entrainment_Homo sapiens_hsa047130.19089225
147SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19071070
148Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.18528359
149Longevity regulating pathway - mammal_Homo sapiens_hsa042110.17930825
150Viral carcinogenesis_Homo sapiens_hsa052030.17365320
151Gastric acid secretion_Homo sapiens_hsa049710.16801677
152Basal cell carcinoma_Homo sapiens_hsa052170.12818523

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