CFAP36

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)6.17096529
2axonemal dynein complex assembly (GO:0070286)5.49583601
3cilium movement (GO:0003341)5.16668155
4epithelial cilium movement (GO:0003351)5.00583409
5acrosome reaction (GO:0007340)4.47715136
6fusion of sperm to egg plasma membrane (GO:0007342)4.46837122
7neuron cell-cell adhesion (GO:0007158)4.31803281
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.31122349
9motile cilium assembly (GO:0044458)4.27008353
10sperm motility (GO:0030317)4.19718203
11mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.11439425
12protein localization to cilium (GO:0061512)4.04079022
13synaptic vesicle exocytosis (GO:0016079)4.02868767
14acrosome assembly (GO:0001675)3.99357740
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.83210744
16axoneme assembly (GO:0035082)3.76223333
17protein localization to synapse (GO:0035418)3.73153606
18vocalization behavior (GO:0071625)3.72481136
19energy coupled proton transport, down electrochemical gradient (GO:0015985)3.72013319
20ATP synthesis coupled proton transport (GO:0015986)3.72013319
21plasma membrane fusion (GO:0045026)3.71762290
22intraciliary transport (GO:0042073)3.71287483
23calcium ion-dependent exocytosis (GO:0017156)3.71271436
24regulation of short-term neuronal synaptic plasticity (GO:0048172)3.67067904
25regulation of cilium movement (GO:0003352)3.64923136
26cell wall macromolecule metabolic process (GO:0044036)3.55483765
27cell wall macromolecule catabolic process (GO:0016998)3.55483765
28protein complex biogenesis (GO:0070271)3.52630738
29regulation of synaptic vesicle exocytosis (GO:2000300)3.49566685
30multicellular organism reproduction (GO:0032504)3.48232439
31transmission of nerve impulse (GO:0019226)3.45767357
32ventricular system development (GO:0021591)3.39591703
33presynaptic membrane assembly (GO:0097105)3.39266253
34negative regulation of inclusion body assembly (GO:0090084)3.36805953
35central nervous system myelination (GO:0022010)3.32835808
36axon ensheathment in central nervous system (GO:0032291)3.32835808
37neuronal action potential propagation (GO:0019227)3.31377969
38positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.29583337
39glutamate secretion (GO:0014047)3.28200597
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.27499594
41mitochondrial respiratory chain complex I assembly (GO:0032981)3.27325838
42NADH dehydrogenase complex assembly (GO:0010257)3.27325838
43mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.27325838
44electron transport chain (GO:0022900)3.27320488
45negative regulation of neurotransmitter transport (GO:0051589)3.26050480
46respiratory electron transport chain (GO:0022904)3.25503038
47neuron recognition (GO:0008038)3.21724427
48sperm-egg recognition (GO:0035036)3.18219116
49left/right pattern formation (GO:0060972)3.17930742
50locomotory exploration behavior (GO:0035641)3.16363652
51protein neddylation (GO:0045116)3.16203513
52ionotropic glutamate receptor signaling pathway (GO:0035235)3.15280591
53detection of calcium ion (GO:0005513)3.14762003
54spermatid development (GO:0007286)3.13216210
55mitochondrial respiratory chain complex assembly (GO:0033108)3.12857148
56piRNA metabolic process (GO:0034587)3.12309020
57establishment of protein localization to mitochondrial membrane (GO:0090151)3.12257683
58nonmotile primary cilium assembly (GO:0035058)3.11569380
59glutamate receptor signaling pathway (GO:0007215)3.10554378
60presynaptic membrane organization (GO:0097090)3.09802942
61pyrimidine nucleobase catabolic process (GO:0006208)3.08502365
62gamma-aminobutyric acid signaling pathway (GO:0007214)3.08421575
63synaptic vesicle maturation (GO:0016188)3.08107500
64chaperone-mediated protein transport (GO:0072321)3.06605452
65neuron-neuron synaptic transmission (GO:0007270)3.05868755
66regulation of synaptic vesicle transport (GO:1902803)3.05527650
67behavioral response to nicotine (GO:0035095)3.05187027
68neuron fate determination (GO:0048664)3.01666507
69exploration behavior (GO:0035640)2.99156835
70ATP hydrolysis coupled proton transport (GO:0015991)2.96922109
71energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.96922109
72regulation of glutamate receptor signaling pathway (GO:1900449)2.96171595
73synaptic transmission, glutamatergic (GO:0035249)2.95763839
74regulation of microtubule-based movement (GO:0060632)2.93970169
75male meiosis (GO:0007140)2.91589892
76regulation of long-term neuronal synaptic plasticity (GO:0048169)2.86833350
77cilium morphogenesis (GO:0060271)2.82645769
78negative regulation of synaptic transmission, GABAergic (GO:0032229)2.82252546
79regulation of vesicle fusion (GO:0031338)2.82061771
80postsynaptic membrane organization (GO:0001941)2.81084368
81regulation of neuronal synaptic plasticity (GO:0048168)2.80078177
82negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.79866537
83retinal ganglion cell axon guidance (GO:0031290)2.79687142
84neurotransmitter secretion (GO:0007269)2.77790424
85mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.77736721
86binding of sperm to zona pellucida (GO:0007339)2.76458274
87negative regulation of neurotransmitter secretion (GO:0046929)2.75846959
88protein-cofactor linkage (GO:0018065)2.75483784
89long-term synaptic potentiation (GO:0060291)2.75106411
90reproduction (GO:0000003)2.74721001
91nucleobase catabolic process (GO:0046113)2.74382557
92microtubule bundle formation (GO:0001578)2.74313836
93cilium organization (GO:0044782)2.74009381
94startle response (GO:0001964)2.72737071
95regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.72530377
96single fertilization (GO:0007338)2.72301858
97dendritic spine morphogenesis (GO:0060997)2.72164919
98cell-cell recognition (GO:0009988)2.71932536
99cilium assembly (GO:0042384)2.71001812
100sperm capacitation (GO:0048240)2.68568217
101neuronal ion channel clustering (GO:0045161)2.67988378
102long-chain fatty acid biosynthetic process (GO:0042759)2.67268258
103axonal fasciculation (GO:0007413)2.67242310
104microtubule-based movement (GO:0007018)2.66448251
105membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.64881485
106mating behavior (GO:0007617)2.64793772
107regulation of protein kinase A signaling (GO:0010738)2.64646643
108neurotransmitter transport (GO:0006836)2.64015525
109protein polyglutamylation (GO:0018095)2.63062114
110G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.62504147
111substantia nigra development (GO:0021762)2.61670519
112regulation of excitatory postsynaptic membrane potential (GO:0060079)2.60684400
113cellular component assembly involved in morphogenesis (GO:0010927)2.60090293
114positive regulation of membrane potential (GO:0045838)2.59300819
115regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.58622615
116smoothened signaling pathway (GO:0007224)2.58427785
117regulation of dopamine metabolic process (GO:0042053)2.58256948
118regulation of catecholamine metabolic process (GO:0042069)2.58256948
119innervation (GO:0060384)2.57464243
120auditory behavior (GO:0031223)2.57089271
121regulation of neurotransmitter secretion (GO:0046928)2.54520827
122regulation of inclusion body assembly (GO:0090083)2.54451053
123positive regulation of synapse assembly (GO:0051965)2.52646100
124microtubule severing (GO:0051013)2.52404004
125gamma-aminobutyric acid transport (GO:0015812)2.52087580
126membrane depolarization during action potential (GO:0086010)2.51663799
127positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.51453731
128regulation of postsynaptic membrane potential (GO:0060078)2.51093913
129retinal cone cell development (GO:0046549)2.50802062
130respiratory chain complex IV assembly (GO:0008535)2.50138184
131hydrogen ion transmembrane transport (GO:1902600)2.47555358
132neurofilament cytoskeleton organization (GO:0060052)2.42195674
133behavioral response to cocaine (GO:0048148)2.42098046
134centriole replication (GO:0007099)2.40725615
135left/right axis specification (GO:0070986)2.40439015
136negative regulation of transcription regulatory region DNA binding (GO:2000678)2.40293997
137ATP biosynthetic process (GO:0006754)2.39125177
138sequestering of actin monomers (GO:0042989)2.37213573
139behavioral defense response (GO:0002209)2.36751959
140behavioral fear response (GO:0001662)2.36751959
141substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.35489203
142substrate-independent telencephalic tangential migration (GO:0021826)2.35489203
143proton transport (GO:0015992)2.35354749
144regulation of neurotransmitter uptake (GO:0051580)2.35155845
145purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.34138699
146regulation of glucokinase activity (GO:0033131)2.33752340
147regulation of hexokinase activity (GO:1903299)2.33752340
148purine nucleoside triphosphate biosynthetic process (GO:0009145)2.33132671
149positive regulation of meiosis (GO:0045836)2.32683943
150mechanosensory behavior (GO:0007638)2.32064053
151hydrogen transport (GO:0006818)2.31549580
152dopamine transport (GO:0015872)2.30770065
153photoreceptor cell development (GO:0042461)2.30491064
154negative regulation of appetite (GO:0032099)2.30431080
155negative regulation of response to food (GO:0032096)2.30431080
156inner ear receptor stereocilium organization (GO:0060122)2.30283765
157negative regulation of cytosolic calcium ion concentration (GO:0051481)2.28398557
158limb development (GO:0060173)2.27895881
159appendage development (GO:0048736)2.27895881
160response to pheromone (GO:0019236)2.26795837

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.31089687
2GBX2_23144817_ChIP-Seq_PC3_Human3.38625405
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.84862137
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.56573751
5TAF15_26573619_Chip-Seq_HEK293_Human2.41267354
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.33031613
7REST_21632747_ChIP-Seq_MESCs_Mouse2.31437961
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18553128
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.18177960
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.16077412
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.15578685
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.09064578
13VDR_22108803_ChIP-Seq_LS180_Human2.05690641
14EWS_26573619_Chip-Seq_HEK293_Human2.04871961
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.98450377
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.97104104
17EZH2_27304074_Chip-Seq_ESCs_Mouse1.95628197
18CTBP1_25329375_ChIP-Seq_LNCAP_Human1.94171520
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.91643972
20POU3F2_20337985_ChIP-ChIP_501MEL_Human1.89273210
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.88250012
22MTF2_20144788_ChIP-Seq_MESCs_Mouse1.87366345
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.86006375
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.84933595
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.83098322
26ZNF274_21170338_ChIP-Seq_K562_Hela1.81679829
27JARID2_20075857_ChIP-Seq_MESCs_Mouse1.81027556
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79646194
29RNF2_18974828_ChIP-Seq_MESCs_Mouse1.78853834
30EZH2_18974828_ChIP-Seq_MESCs_Mouse1.78853834
31FUS_26573619_Chip-Seq_HEK293_Human1.76683368
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.76578826
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.75441109
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75222301
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.73187329
36SMAD4_21799915_ChIP-Seq_A2780_Human1.72819518
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71438948
38GABP_17652178_ChIP-ChIP_JURKAT_Human1.71353040
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69220433
40P300_19829295_ChIP-Seq_ESCs_Human1.68878614
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67508843
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.66638047
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.64803599
44RNF2_27304074_Chip-Seq_ESCs_Mouse1.58825082
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56014304
46ER_23166858_ChIP-Seq_MCF-7_Human1.55977038
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.53741299
48RNF2_27304074_Chip-Seq_NSC_Mouse1.53676517
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.53165191
50RARB_27405468_Chip-Seq_BRAIN_Mouse1.52832547
51CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50141090
52DROSHA_22980978_ChIP-Seq_HELA_Human1.48230637
53PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.47493265
54PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47445515
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43886911
56IGF1R_20145208_ChIP-Seq_DFB_Human1.43775464
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.43395842
58BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39458424
59KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.38834096
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.36298541
61FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.36255974
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34819999
63RBPJ_22232070_ChIP-Seq_NCS_Mouse1.33952247
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.33253870
65STAT3_23295773_ChIP-Seq_U87_Human1.30668885
66NANOG_18555785_Chip-Seq_ESCs_Mouse1.29382048
67SALL1_21062744_ChIP-ChIP_HESCs_Human1.29275611
68MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29255024
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.29171445
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28206743
71AR_21572438_ChIP-Seq_LNCaP_Human1.27958814
72MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27716014
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.27263187
74RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.25248094
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24411651
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24350837
77TCF4_23295773_ChIP-Seq_U87_Human1.24256574
78CDX2_19796622_ChIP-Seq_MESCs_Mouse1.23087179
79TP53_22573176_ChIP-Seq_HFKS_Human1.20110324
80MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19642085
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19338608
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19096370
83TAL1_26923725_Chip-Seq_HPCs_Mouse1.18722972
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18561923
85RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.17837767
86PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16874640
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.16845665
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16450414
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16226499
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16226499
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15791339
92NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15714387
93AR_25329375_ChIP-Seq_VCAP_Human1.14992607
94IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13405869
95KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13330436
96CBP_20019798_ChIP-Seq_JUKART_Human1.12540155
97IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12540155
98JUN_21703547_ChIP-Seq_K562_Human1.10607565
99PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.10338395
100RUNX2_22187159_ChIP-Seq_PCA_Human1.10067985
101FLI1_21867929_ChIP-Seq_TH2_Mouse1.09995960
102KDM2B_26808549_Chip-Seq_REH_Human1.09900483
103TCF4_22108803_ChIP-Seq_LS180_Human1.09772495
104TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.08000092
105P53_22387025_ChIP-Seq_ESCs_Mouse1.07867957
106MYC_18940864_ChIP-ChIP_HL60_Human1.07601597
107SOX2_21211035_ChIP-Seq_LN229_Gbm1.07393407
108CMYC_18555785_Chip-Seq_ESCs_Mouse1.07233223
109NANOG_19829295_ChIP-Seq_ESCs_Human1.03353444
110SOX2_19829295_ChIP-Seq_ESCs_Human1.03353444
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03162903
112BCAT_22108803_ChIP-Seq_LS180_Human1.02652387
113E2F1_18555785_Chip-Seq_ESCs_Mouse1.01388146
114SOX9_26525672_Chip-Seq_HEART_Mouse1.01238586
115NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00926792
116GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98270640
117SUZ12_18555785_Chip-Seq_ESCs_Mouse0.98028890
118P300_18555785_Chip-Seq_ESCs_Mouse0.97384028
119RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96906424
120PRDM14_20953172_ChIP-Seq_ESCs_Human0.95751028
121EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.94086736

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.58395232
2MP0005410_abnormal_fertilization4.08065467
3MP0004859_abnormal_synaptic_plasticity3.98806029
4MP0004270_analgesia3.35839585
5MP0003635_abnormal_synaptic_transmissio3.10195941
6MP0009745_abnormal_behavioral_response2.68739438
7MP0009046_muscle_twitch2.68192638
8MP0002064_seizures2.60278109
9MP0002063_abnormal_learning/memory/cond2.53591940
10MP0002272_abnormal_nervous_system2.51020885
11MP0001968_abnormal_touch/_nociception2.48038149
12MP0001984_abnormal_olfaction2.43293082
13MP0002734_abnormal_mechanical_nocicepti2.40616396
14MP0002572_abnormal_emotion/affect_behav2.40457465
15MP0005423_abnormal_somatic_nervous2.25822310
16MP0001529_abnormal_vocalization2.25057125
17MP0001486_abnormal_startle_reflex2.17851221
18MP0002736_abnormal_nociception_after2.05862603
19MP0001440_abnormal_grooming_behavior2.03473556
20MP0001905_abnormal_dopamine_level2.03435759
21MP0006276_abnormal_autonomic_nervous2.00769722
22MP0002735_abnormal_chemical_nociception1.97074053
23MP0000778_abnormal_nervous_system1.96557120
24MP0002822_catalepsy1.92084663
25MP0006292_abnormal_olfactory_placode1.88393800
26MP0002067_abnormal_sensory_capabilities1.79615722
27MP0003329_amyloid_beta_deposits1.76659984
28MP0002102_abnormal_ear_morphology1.75544521
29MP0003698_abnormal_male_reproductive1.73448725
30MP0005551_abnormal_eye_electrophysiolog1.73337046
31MP0005646_abnormal_pituitary_gland1.70508312
32MP0002733_abnormal_thermal_nociception1.70466565
33MP0004133_heterotaxia1.70024240
34MP0001970_abnormal_pain_threshold1.66671625
35MP0001501_abnormal_sleep_pattern1.65463387
36MP0005645_abnormal_hypothalamus_physiol1.62700634
37MP0002184_abnormal_innervation1.59059362
38MP0003121_genomic_imprinting1.56900206
39MP0002557_abnormal_social/conspecific_i1.56094785
40MP0000013_abnormal_adipose_tissue1.54156165
41MP0008789_abnormal_olfactory_epithelium1.53173454
42MP0008877_abnormal_DNA_methylation1.50012146
43MP0005386_behavior/neurological_phenoty1.49169992
44MP0004924_abnormal_behavior1.49169992
45MP0000955_abnormal_spinal_cord1.47592714
46MP0005623_abnormal_meninges_morphology1.44982988
47MP0002938_white_spotting1.44967639
48MP0006072_abnormal_retinal_apoptosis1.44788598
49MP0002882_abnormal_neuron_morphology1.43438611
50MP0003136_yellow_coat_color1.41750338
51MP0009379_abnormal_foot_pigmentation1.40232751
52MP0000566_synostosis1.40115924
53MP0009780_abnormal_chondrocyte_physiolo1.39269539
54MP0002909_abnormal_adrenal_gland1.38912990
55MP0000920_abnormal_myelination1.37821382
56MP0001188_hyperpigmentation1.37139475
57MP0004742_abnormal_vestibular_system1.36191423
58MP0003122_maternal_imprinting1.34952722
59MP0004142_abnormal_muscle_tone1.33936961
60MP0002229_neurodegeneration1.32571163
61MP0004885_abnormal_endolymph1.31298655
62MP0002837_dystrophic_cardiac_calcinosis1.29960969
63MP0002653_abnormal_ependyma_morphology1.29486071
64MP0001502_abnormal_circadian_rhythm1.29012044
65MP0002066_abnormal_motor_capabilities/c1.27784303
66MP0004811_abnormal_neuron_physiology1.27497924
67MP0008569_lethality_at_weaning1.26973527
68MP0003634_abnormal_glial_cell1.26209745
69MP0001929_abnormal_gametogenesis1.25561112
70MP0002928_abnormal_bile_duct1.23023916
71MP0008995_early_reproductive_senescence1.21037028
72MP0010386_abnormal_urinary_bladder1.16977615
73MP0000631_abnormal_neuroendocrine_gland1.15492689
74MP0000569_abnormal_digit_pigmentation1.13623571
75MP0004858_abnormal_nervous_system1.09572760
76MP0001485_abnormal_pinna_reflex1.08758311
77MP0005409_darkened_coat_color1.08298433
78MP0002152_abnormal_brain_morphology1.08189759
79MP0003633_abnormal_nervous_system1.07816398
80MP0005084_abnormal_gallbladder_morpholo1.07697837
81MP0005253_abnormal_eye_physiology1.07516314
82MP0002752_abnormal_somatic_nervous1.06445706
83MP0003123_paternal_imprinting1.06256765
84MP0003011_delayed_dark_adaptation1.06116577
85MP0001963_abnormal_hearing_physiology1.02901516
86MP0000049_abnormal_middle_ear1.02829817
87MP0003787_abnormal_imprinting1.02579322
88MP0005171_absent_coat_pigmentation1.02057514
89MP0008875_abnormal_xenobiotic_pharmacok1.00578154
90MP0003631_nervous_system_phenotype1.00077783
91MP0002234_abnormal_pharynx_morphology0.99766252
92MP0003195_calcinosis0.97881681
93MP0004145_abnormal_muscle_electrophysio0.95688618
94MP0005187_abnormal_penis_morphology0.93979031
95MP0005379_endocrine/exocrine_gland_phen0.93794460
96MP0003879_abnormal_hair_cell0.93455705
97MP0002638_abnormal_pupillary_reflex0.91696003
98MP0004043_abnormal_pH_regulation0.90657927
99MP0003938_abnormal_ear_development0.90470891
100MP0002876_abnormal_thyroid_physiology0.89926855
101MP0001986_abnormal_taste_sensitivity0.89325401
102MP0001293_anophthalmia0.88891904
103MP0002751_abnormal_autonomic_nervous0.88443844
104MP0008872_abnormal_physiological_respon0.88407268
105MP0000372_irregular_coat_pigmentation0.88228938
106MP0002161_abnormal_fertility/fecundity0.86167360
107MP0001299_abnormal_eye_distance/0.85537876
108MP0003690_abnormal_glial_cell0.84792702
109MP0003632_abnormal_nervous_system0.84439568
110MP0003861_abnormal_nervous_system0.81048523
111MP0002160_abnormal_reproductive_system0.80544587
112MP0005391_vision/eye_phenotype0.79525006
113MP0008058_abnormal_DNA_repair0.79333981
114MP0005499_abnormal_olfactory_system0.76566172
115MP0005394_taste/olfaction_phenotype0.76566172
116MP0002069_abnormal_eating/drinking_beha0.73713189
117MP0003283_abnormal_digestive_organ0.73108852
118MP0000026_abnormal_inner_ear0.73059015
119MP0005195_abnormal_posterior_eye0.72491794
120MP0001177_atelectasis0.72261441
121MP0004134_abnormal_chest_morphology0.71893940
122MP0002210_abnormal_sex_determination0.68231289
123MP0005535_abnormal_body_temperature0.67372538
124MP0001765_abnormal_ion_homeostasis0.66143017
125MP0002090_abnormal_vision0.64991817
126MP0004085_abnormal_heartbeat0.64851555
127MP0001664_abnormal_digestion0.63703320

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.35354846
2Absent/shortened dynein arms (HP:0200106)6.78517852
3Dynein arm defect of respiratory motile cilia (HP:0012255)6.78517852
4Abnormal respiratory motile cilium physiology (HP:0012261)6.55601002
5Abnormal ciliary motility (HP:0012262)6.31915505
6Abnormal respiratory epithelium morphology (HP:0012253)5.58010586
7Abnormal respiratory motile cilium morphology (HP:0005938)5.58010586
8Rhinitis (HP:0012384)5.12974595
9Pancreatic cysts (HP:0001737)3.99045411
10Focal motor seizures (HP:0011153)3.97973674
11Medial flaring of the eyebrow (HP:0010747)3.68399982
12Chronic bronchitis (HP:0004469)3.64983273
13Gait imbalance (HP:0002141)3.43965357
14Myokymia (HP:0002411)3.32683010
15Atonic seizures (HP:0010819)3.28216118
16Congenital primary aphakia (HP:0007707)3.24236739
17Epileptic encephalopathy (HP:0200134)3.18855552
18Nephronophthisis (HP:0000090)3.12127277
19Retinal dysplasia (HP:0007973)3.11714538
20Neurofibrillary tangles (HP:0002185)3.08974372
21Infertility (HP:0000789)3.05874615
22Cystic liver disease (HP:0006706)3.03554322
23Focal seizures (HP:0007359)2.99966899
24Visual hallucinations (HP:0002367)2.98961106
25Nephrogenic diabetes insipidus (HP:0009806)2.93171154
26Genital tract atresia (HP:0001827)2.89195680
27Vaginal atresia (HP:0000148)2.87332872
28Cerebral inclusion bodies (HP:0100314)2.82639218
29Congenital stationary night blindness (HP:0007642)2.81960679
30Progressive cerebellar ataxia (HP:0002073)2.79148601
31Molar tooth sign on MRI (HP:0002419)2.72764826
32Abnormality of midbrain morphology (HP:0002418)2.72764826
33Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.69786156
34Degeneration of the lateral corticospinal tracts (HP:0002314)2.69786156
35Occipital encephalocele (HP:0002085)2.67846888
36Acute necrotizing encephalopathy (HP:0006965)2.66642756
37Increased hepatocellular lipid droplets (HP:0006565)2.64504907
38Sclerocornea (HP:0000647)2.64086182
39Supranuclear gaze palsy (HP:0000605)2.62862034
40Pheochromocytoma (HP:0002666)2.62504653
41Anencephaly (HP:0002323)2.56447798
42Hyperventilation (HP:0002883)2.55294902
43Increased CSF lactate (HP:0002490)2.53443025
44Lipid accumulation in hepatocytes (HP:0006561)2.51264842
45Bronchiectasis (HP:0002110)2.43970382
46Postaxial foot polydactyly (HP:0001830)2.43347159
47Oligodactyly (hands) (HP:0001180)2.41599557
48Neuroendocrine neoplasm (HP:0100634)2.41209415
49Progressive macrocephaly (HP:0004481)2.39549574
50Absence seizures (HP:0002121)2.37089100
51Polyphagia (HP:0002591)2.35512019
52Male pseudohermaphroditism (HP:0000037)2.34155333
53Limb dystonia (HP:0002451)2.31739909
54Abnormal mitochondria in muscle tissue (HP:0008316)2.29416608
55Abnormality of the renal medulla (HP:0100957)2.29086258
56Type II lissencephaly (HP:0007260)2.28483296
57Congenital hepatic fibrosis (HP:0002612)2.25270910
58Aplasia/Hypoplasia of the lens (HP:0008063)2.23751319
59Abnormality of the corticospinal tract (HP:0002492)2.23675954
60Dialeptic seizures (HP:0011146)2.23037579
61Abnormal rod and cone electroretinograms (HP:0008323)2.22687947
62Poor coordination (HP:0002370)2.20651630
63Hepatic necrosis (HP:0002605)2.18019524
64Hepatocellular necrosis (HP:0001404)2.16704535
65Renal Fanconi syndrome (HP:0001994)2.15628980
66Tubulointerstitial nephritis (HP:0001970)2.14269938
67Furrowed tongue (HP:0000221)2.13619262
68Febrile seizures (HP:0002373)2.13517613
69Hemiparesis (HP:0001269)2.13420500
70Chronic hepatic failure (HP:0100626)2.12756155
713-Methylglutaconic aciduria (HP:0003535)2.11984426
72Gaze-evoked nystagmus (HP:0000640)2.08982155
73Abnormality of the renal cortex (HP:0011035)2.08100639
74Pancreatic fibrosis (HP:0100732)2.07144999
75Abnormality of the labia minora (HP:0012880)2.00964179
76Preaxial hand polydactyly (HP:0001177)1.97447813
77Dysmetria (HP:0001310)1.97148214
78Generalized tonic-clonic seizures (HP:0002069)1.96808006
79Sensory axonal neuropathy (HP:0003390)1.96371901
80Hypothermia (HP:0002045)1.96091593
81Peripheral hypomyelination (HP:0007182)1.94705174
82Truncal ataxia (HP:0002078)1.94264705
83Intestinal atresia (HP:0011100)1.92632044
84Progressive inability to walk (HP:0002505)1.92359278
85Mitochondrial inheritance (HP:0001427)1.92119384
86Amblyopia (HP:0000646)1.91692256
87Acute encephalopathy (HP:0006846)1.91679913
88Postaxial hand polydactyly (HP:0001162)1.91391510
89Narrow forehead (HP:0000341)1.90872942
90True hermaphroditism (HP:0010459)1.90624713
91Tubular atrophy (HP:0000092)1.90355528
92Specific learning disability (HP:0001328)1.90064367
93Abnormality of macular pigmentation (HP:0008002)1.88983024
94Anxiety (HP:0000739)1.88938254
95Optic nerve hypoplasia (HP:0000609)1.87582687
96Optic disc pallor (HP:0000543)1.87529566
97Delusions (HP:0000746)1.87424245
98Broad-based gait (HP:0002136)1.85166396
99Action tremor (HP:0002345)1.84807861
100Epileptiform EEG discharges (HP:0011182)1.81757946
101Cerebral edema (HP:0002181)1.80349556
102Anophthalmia (HP:0000528)1.79438879
103Scanning speech (HP:0002168)1.78285037
104EEG with generalized epileptiform discharges (HP:0011198)1.76155936
105Bifid tongue (HP:0010297)1.74780989
106Dysdiadochokinesis (HP:0002075)1.74529804
107Leukodystrophy (HP:0002415)1.73736766
108Ankle clonus (HP:0011448)1.71844823
109Oculomotor apraxia (HP:0000657)1.70581979
110Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.70206878
111Decreased activity of mitochondrial respiratory chain (HP:0008972)1.70206878
112Spastic gait (HP:0002064)1.70131568
113Abnormality of renal resorption (HP:0011038)1.69832684
114Agitation (HP:0000713)1.69492466
115Megalencephaly (HP:0001355)1.68696893
116Absent rod-and cone-mediated responses on ERG (HP:0007688)1.66170347
117Absent speech (HP:0001344)1.65960633
118Oligodactyly (HP:0012165)1.65832826
119Exertional dyspnea (HP:0002875)1.65741276
120Drooling (HP:0002307)1.65713100
121Increased circulating renin level (HP:0000848)1.65349062
122Aganglionic megacolon (HP:0002251)1.65170882
123Insidious onset (HP:0003587)1.64964715
124Termporal pattern (HP:0011008)1.64964715
125Prominent nasal bridge (HP:0000426)1.64651130
126Intention tremor (HP:0002080)1.64624732
127Hypsarrhythmia (HP:0002521)1.64430567
128Median cleft lip (HP:0000161)1.62028339
129Hypoplasia of the brainstem (HP:0002365)1.61804100
130Aplasia/Hypoplasia of the brainstem (HP:0007362)1.61804100
131Abnormality of dentin (HP:0010299)1.60883428
132Delayed gross motor development (HP:0002194)1.58694974
133Aplasia/Hypoplasia of the tongue (HP:0010295)1.57644516
134Amyotrophic lateral sclerosis (HP:0007354)1.56909605
135Polydipsia (HP:0001959)1.56679582
136Abnormal drinking behavior (HP:0030082)1.56679582
137Nasal polyposis (HP:0100582)1.55835964
138Widely spaced teeth (HP:0000687)1.55538831
139Abnormal eating behavior (HP:0100738)1.55180986
140Taurodontia (HP:0000679)1.54238104
141Abnormality of permanent molar morphology (HP:0011071)1.54238104

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK3.74157521
2FRK3.26066959
3NTRK33.10573185
4STK393.04360887
5EPHA42.94018590
6PDK42.87777887
7PDK32.87777887
8MAP4K22.72311128
9CASK2.66229024
10MAP3K42.45430408
11WNK42.34809650
12TNIK2.33816337
13MAP2K72.33385922
14PRKD32.18836779
15MINK12.04698699
16MARK12.03802839
17GRK11.95710719
18OXSR11.95532164
19ARAF1.83178719
20MAP3K91.81889649
21PLK21.77477614
22MAP3K121.76018160
23PTK2B1.68885165
24PDK21.68081604
25TRIM281.65697947
26NTRK11.61894664
27BCR1.57989404
28NTRK21.53730619
29ERBB31.48595476
30TESK11.46759530
31PAK61.43265618
32GRK51.42885935
33PRPF4B1.41581063
34MST41.39777513
35UHMK11.38247533
36MAPK151.37090089
37MAPK131.25323694
38WNK11.23679357
39NUAK11.21679397
40RIPK41.19059966
41NME11.16834740
42WNK31.16411086
43CDK191.15940712
44CDK51.13995882
45CAMK2A1.13589681
46PRKCG1.13254736
47MAP2K41.11732394
48CAMK2B1.11059531
49PAK31.04859224
50MAPKAPK51.04204990
51BMPR20.96223195
52CDK140.93590814
53TYRO30.92118857
54CAMKK20.92028596
55CAMK2D0.91108355
56SGK2230.88906656
57SGK4940.88906656
58CSNK1G20.85418940
59KSR20.83473113
60BRAF0.81782353
61FGR0.80564830
62GRK70.80480298
63CDK180.80076143
64ICK0.79508871
65PLK30.78917717
66CCNB10.78750788
67FES0.77043868
68CDK150.76798415
69MKNK20.76647494
70PRKCE0.75833381
71DYRK30.75308721
72VRK10.74748447
73PASK0.74531170
74NEK60.74293495
75EPHB20.74184255
76LIMK10.74083402
77DAPK20.73515749
78TLK10.72501469
79TSSK60.71829901
80PKN10.71562930
81DYRK1A0.71242160
82CSNK1G30.70571336
83MAP3K20.69792313
84STK38L0.69667027
85KSR10.68069175
86ZAK0.68008863
87CDK30.67974475
88CDK11A0.66425307
89TGFBR10.64820267
90BCKDK0.64544075
91PHKG20.63869896
92PHKG10.63869896
93ROCK20.63115686
94CAMK2G0.62991391
95PLK40.61285635
96CAMKK10.61119082
97IRAK10.59210524
98BMPR1B0.58802323
99AKT30.58774553
100STK160.57556676
101CAMK10.55659030
102ADRBK20.55215217
103DAPK10.54541262
104CDK80.53925312
105CSNK1E0.53839312
106MKNK10.52891083
107INSRR0.52653294
108PINK10.52554418
109IRAK20.52384524
110CSNK1A1L0.50280561
111ADRBK10.49161709
112CSNK1A10.49069528
113WEE10.47864501
114SGK20.47415402
115STK30.45356899
116CAMK1G0.44198678
117DYRK20.43687527
118VRK20.42721848
119STK110.42573555
120PRKACA0.42023798
121MUSK0.41260623
122PLK10.40805674
123FGFR20.40535180
124PRKG10.39956091
125PDK10.39291407
126PDPK10.39237049
127SIK20.38899097
128PRKACB0.38729796
129FER0.38509346
130STK380.37360886
131TAOK30.35966198
132PRKCZ0.35280948
133EPHA30.34642036
134MAPK100.34202613
135SGK10.33575471
136CSNK1G10.32824576
137PRKCQ0.31818250
138MARK20.31494919

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.18919239
2Synaptic vesicle cycle_Homo sapiens_hsa047212.95968301
3Oxidative phosphorylation_Homo sapiens_hsa001902.79777296
4Collecting duct acid secretion_Homo sapiens_hsa049662.51352712
5Ribosome_Homo sapiens_hsa030102.44920218
6Amphetamine addiction_Homo sapiens_hsa050312.43437381
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36344570
8GABAergic synapse_Homo sapiens_hsa047272.31969698
9Long-term potentiation_Homo sapiens_hsa047202.27172776
10Olfactory transduction_Homo sapiens_hsa047402.24629173
11Circadian entrainment_Homo sapiens_hsa047132.22031062
12Glutamatergic synapse_Homo sapiens_hsa047242.18264018
13Parkinsons disease_Homo sapiens_hsa050122.14978099
14Morphine addiction_Homo sapiens_hsa050322.07445977
15Alzheimers disease_Homo sapiens_hsa050102.06109505
16Dopaminergic synapse_Homo sapiens_hsa047282.05567298
17Huntingtons disease_Homo sapiens_hsa050161.97310779
18Taste transduction_Homo sapiens_hsa047421.96807676
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.90083873
20Insulin secretion_Homo sapiens_hsa049111.88719023
21Serotonergic synapse_Homo sapiens_hsa047261.88457144
22Vibrio cholerae infection_Homo sapiens_hsa051101.88456444
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77483466
24Cardiac muscle contraction_Homo sapiens_hsa042601.74753648
25Renin secretion_Homo sapiens_hsa049241.73450365
26Phototransduction_Homo sapiens_hsa047441.72783085
27Cocaine addiction_Homo sapiens_hsa050301.65254281
28Salivary secretion_Homo sapiens_hsa049701.65129963
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53252929
30Long-term depression_Homo sapiens_hsa047301.52594733
31Cholinergic synapse_Homo sapiens_hsa047251.46476338
32Protein export_Homo sapiens_hsa030601.43378752
33Gastric acid secretion_Homo sapiens_hsa049711.40709063
34Propanoate metabolism_Homo sapiens_hsa006401.35095786
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.34462230
36Calcium signaling pathway_Homo sapiens_hsa040201.33214218
37RNA polymerase_Homo sapiens_hsa030201.32951318
38Basal transcription factors_Homo sapiens_hsa030221.27068776
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23964045
40Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20945648
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.20878734
42Axon guidance_Homo sapiens_hsa043601.19800624
43Oxytocin signaling pathway_Homo sapiens_hsa049211.19396138
44Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.18524964
45Sulfur metabolism_Homo sapiens_hsa009201.14905509
46Ether lipid metabolism_Homo sapiens_hsa005651.06934369
47Nitrogen metabolism_Homo sapiens_hsa009101.03968430
48Gap junction_Homo sapiens_hsa045401.02363490
49beta-Alanine metabolism_Homo sapiens_hsa004101.01453694
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.99589900
51Oocyte meiosis_Homo sapiens_hsa041140.96537791
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.96501295
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.96323763
54cAMP signaling pathway_Homo sapiens_hsa040240.96091745
55RNA degradation_Homo sapiens_hsa030180.95761070
56Estrogen signaling pathway_Homo sapiens_hsa049150.94825014
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.93347527
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.92139797
59Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.91111274
60Homologous recombination_Homo sapiens_hsa034400.90905359
61Primary bile acid biosynthesis_Homo sapiens_hsa001200.90563777
62Peroxisome_Homo sapiens_hsa041460.90313622
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89570105
64GnRH signaling pathway_Homo sapiens_hsa049120.88820631
65Dorso-ventral axis formation_Homo sapiens_hsa043200.88697792
66Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88508945
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86036777
68cGMP-PKG signaling pathway_Homo sapiens_hsa040220.85803432
69Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.85053039
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84926857
71Proteasome_Homo sapiens_hsa030500.84829008
72Regulation of autophagy_Homo sapiens_hsa041400.83421013
73Pyruvate metabolism_Homo sapiens_hsa006200.83337513
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82125884
75Folate biosynthesis_Homo sapiens_hsa007900.82002079
76Chemical carcinogenesis_Homo sapiens_hsa052040.80945485
77Pancreatic secretion_Homo sapiens_hsa049720.80751176
78Thyroid hormone synthesis_Homo sapiens_hsa049180.79700998
79Glucagon signaling pathway_Homo sapiens_hsa049220.78769542
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76703880
81Alcoholism_Homo sapiens_hsa050340.74280599
82Melanogenesis_Homo sapiens_hsa049160.74262446
83Tryptophan metabolism_Homo sapiens_hsa003800.74138873
84Fanconi anemia pathway_Homo sapiens_hsa034600.72940564
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.68704332
86Selenocompound metabolism_Homo sapiens_hsa004500.68644774
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66565531
88Vitamin B6 metabolism_Homo sapiens_hsa007500.64400829
89Metabolic pathways_Homo sapiens_hsa011000.63359275
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62530297
91Fatty acid elongation_Homo sapiens_hsa000620.61836585
92Purine metabolism_Homo sapiens_hsa002300.61217576
93Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60724240
94Basal cell carcinoma_Homo sapiens_hsa052170.60601999
95Rheumatoid arthritis_Homo sapiens_hsa053230.59541176
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58860325
97Sphingolipid metabolism_Homo sapiens_hsa006000.58774612
98Type II diabetes mellitus_Homo sapiens_hsa049300.58493348
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58485684
100ErbB signaling pathway_Homo sapiens_hsa040120.57107077
101Retinol metabolism_Homo sapiens_hsa008300.54571103
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54040308
103Ras signaling pathway_Homo sapiens_hsa040140.52461809
104Linoleic acid metabolism_Homo sapiens_hsa005910.50979040
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50550990
106Tyrosine metabolism_Homo sapiens_hsa003500.50470493
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50161597
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.49187143
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.48872073
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.48242961
111Phagosome_Homo sapiens_hsa041450.47822029
112Glutathione metabolism_Homo sapiens_hsa004800.47382099
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46890688
114Glioma_Homo sapiens_hsa052140.46704190
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46399772
116Type I diabetes mellitus_Homo sapiens_hsa049400.45246816
117Steroid biosynthesis_Homo sapiens_hsa001000.45170363
118Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44818732
119Choline metabolism in cancer_Homo sapiens_hsa052310.44654996
120Histidine metabolism_Homo sapiens_hsa003400.44371650
121Sulfur relay system_Homo sapiens_hsa041220.42970291
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42132013
123Hippo signaling pathway_Homo sapiens_hsa043900.41580830
124Wnt signaling pathway_Homo sapiens_hsa043100.41459289
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41349393
126Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.40270122
127Cysteine and methionine metabolism_Homo sapiens_hsa002700.39583552
128MAPK signaling pathway_Homo sapiens_hsa040100.39433845
129Ovarian steroidogenesis_Homo sapiens_hsa049130.38784289
130Spliceosome_Homo sapiens_hsa030400.38464456
131Glycerophospholipid metabolism_Homo sapiens_hsa005640.38421524
132Sphingolipid signaling pathway_Homo sapiens_hsa040710.38298127
133Non-homologous end-joining_Homo sapiens_hsa034500.37982829
134Endocytosis_Homo sapiens_hsa041440.36893234
135Caffeine metabolism_Homo sapiens_hsa002320.36503587
136Mineral absorption_Homo sapiens_hsa049780.36369485
137Renal cell carcinoma_Homo sapiens_hsa052110.35635349
138Hedgehog signaling pathway_Homo sapiens_hsa043400.35504155
139Butanoate metabolism_Homo sapiens_hsa006500.35141579
140Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35066751
141Inositol phosphate metabolism_Homo sapiens_hsa005620.34774895
142Dilated cardiomyopathy_Homo sapiens_hsa054140.29649050
143Circadian rhythm_Homo sapiens_hsa047100.29473370

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