CFAP69

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.80914333
2fusion of sperm to egg plasma membrane (GO:0007342)8.94779651
3sperm motility (GO:0030317)8.78321382
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.59591617
5sensory perception of smell (GO:0007608)8.08712533
6motile cilium assembly (GO:0044458)7.99635167
7regulation of cilium movement (GO:0003352)7.74419668
8acrosome assembly (GO:0001675)7.66469642
9acrosome reaction (GO:0007340)7.54547259
10multicellular organism reproduction (GO:0032504)7.33221083
11sperm-egg recognition (GO:0035036)7.31720161
12protein localization to cilium (GO:0061512)6.98492425
13plasma membrane fusion (GO:0045026)6.96553031
14cell wall macromolecule metabolic process (GO:0044036)6.82886132
15cell wall macromolecule catabolic process (GO:0016998)6.82886132
16binding of sperm to zona pellucida (GO:0007339)6.76608669
17ventricular system development (GO:0021591)6.65347119
18cell-cell recognition (GO:0009988)6.51024214
19piRNA metabolic process (GO:0034587)6.39593553
20spermatid development (GO:0007286)6.28906396
21reproduction (GO:0000003)6.04146684
22axoneme assembly (GO:0035082)6.01348355
23male meiosis (GO:0007140)5.87417279
24single fertilization (GO:0007338)5.85376346
25intraciliary transport (GO:0042073)5.51778828
26synaptonemal complex organization (GO:0070193)5.25895556
27sensory perception of chemical stimulus (GO:0007606)5.02405182
28negative regulation of inclusion body assembly (GO:0090084)4.95411878
29sperm capacitation (GO:0048240)4.89854875
30regulation of microtubule-based movement (GO:0060632)4.85183652
31fertilization (GO:0009566)4.83641556
32protein insertion into membrane (GO:0051205)4.78387995
33tryptophan catabolic process (GO:0006569)4.74715582
34indole-containing compound catabolic process (GO:0042436)4.74715582
35indolalkylamine catabolic process (GO:0046218)4.74715582
36calcium ion-dependent exocytosis (GO:0017156)4.73164150
37synaptonemal complex assembly (GO:0007130)4.70405513
38indolalkylamine metabolic process (GO:0006586)4.70210374
39protein polyglutamylation (GO:0018095)4.67949938
40microtubule severing (GO:0051013)4.66456142
41cilium morphogenesis (GO:0060271)4.58036741
42kynurenine metabolic process (GO:0070189)4.38562264
43signal peptide processing (GO:0006465)4.35812237
44detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.32379461
45nucleoside diphosphate phosphorylation (GO:0006165)4.26986462
46cilium organization (GO:0044782)4.26010830
47spermatogenesis (GO:0007283)4.23693098
48male gamete generation (GO:0048232)4.21596846
49cilium assembly (GO:0042384)4.17919873
50neural tube formation (GO:0001841)4.16600332
51left/right axis specification (GO:0070986)4.03622680
52tryptophan metabolic process (GO:0006568)4.01301334
53DNA methylation involved in gamete generation (GO:0043046)3.97697465
54microtubule-based movement (GO:0007018)3.92427494
55gamete generation (GO:0007276)3.89599715
56male meiosis I (GO:0007141)3.86118917
57cell recognition (GO:0008037)3.79260801
58left/right pattern formation (GO:0060972)3.76472741
59spermatid nucleus differentiation (GO:0007289)3.75049999
60detection of light stimulus involved in sensory perception (GO:0050962)3.73216063
61detection of light stimulus involved in visual perception (GO:0050908)3.73216063
62regulation of inclusion body assembly (GO:0090083)3.71360913
63behavioral response to nicotine (GO:0035095)3.68406286
64cellular component assembly involved in morphogenesis (GO:0010927)3.66645570
65monoubiquitinated protein deubiquitination (GO:0035520)3.65264386
66regulation of hippo signaling (GO:0035330)3.64404424
67cellular process involved in reproduction in multicellular organism (GO:0022412)3.57037272
68negative regulation of cytosolic calcium ion concentration (GO:0051481)3.56619931
69germ cell development (GO:0007281)3.50632678
70cellular ketone body metabolic process (GO:0046950)3.50304145
71protein K11-linked deubiquitination (GO:0035871)3.47119048
72regulation of chromatin binding (GO:0035561)3.46946055
73GTP biosynthetic process (GO:0006183)3.46214535
74indole-containing compound metabolic process (GO:0042430)3.42403686
75behavioral response to ethanol (GO:0048149)3.40588313
76L-fucose catabolic process (GO:0042355)3.39015484
77fucose catabolic process (GO:0019317)3.39015484
78L-fucose metabolic process (GO:0042354)3.39015484
79regulation of pigment cell differentiation (GO:0050932)3.37671672
80microtubule bundle formation (GO:0001578)3.36768815
81establishment of protein localization to Golgi (GO:0072600)3.36400701
82reflex (GO:0060004)3.33466237
83positive regulation of developmental pigmentation (GO:0048087)3.29408072
84organic cation transport (GO:0015695)3.24573505
85response to pheromone (GO:0019236)3.24341339
86multicellular organismal reproductive process (GO:0048609)3.15618534
87lactate metabolic process (GO:0006089)3.14918363
88microtubule depolymerization (GO:0007019)3.14764811
89tachykinin receptor signaling pathway (GO:0007217)3.14167171
90ketone body metabolic process (GO:1902224)3.13750937
91interkinetic nuclear migration (GO:0022027)3.13016271
92retinal cone cell development (GO:0046549)3.12426121
93benzene-containing compound metabolic process (GO:0042537)3.10832052
94serotonin metabolic process (GO:0042428)3.07494059
95chromosome organization involved in meiosis (GO:0070192)3.04341062
96thyroid hormone metabolic process (GO:0042403)3.03705011
97meiotic nuclear division (GO:0007126)3.01883794
98regulation of sarcomere organization (GO:0060297)3.01151362
99amine catabolic process (GO:0009310)3.00203549
100cellular biogenic amine catabolic process (GO:0042402)3.00203549
101regulation of posttranscriptional gene silencing (GO:0060147)3.00201913
102regulation of gene silencing by miRNA (GO:0060964)3.00201913
103regulation of gene silencing by RNA (GO:0060966)3.00201913
104snRNA transcription (GO:0009301)2.99311816
105protein K48-linked deubiquitination (GO:0071108)2.99065591
106centriole replication (GO:0007099)2.98431829
107gamma-aminobutyric acid transport (GO:0015812)2.98343688
108UTP biosynthetic process (GO:0006228)2.94524842
109meiosis I (GO:0007127)2.93863854
110oxidative demethylation (GO:0070989)2.93139577
111negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89181785
112negative regulation of translation, ncRNA-mediated (GO:0040033)2.89181785
113regulation of translation, ncRNA-mediated (GO:0045974)2.89181785
114cellular response to sterol (GO:0036315)2.88887725
115detection of mechanical stimulus involved in sensory perception (GO:0050974)2.85033964
116neuron cell-cell adhesion (GO:0007158)2.84238774
117auditory receptor cell stereocilium organization (GO:0060088)2.82837711
118primary amino compound metabolic process (GO:1901160)2.82343373
119membrane depolarization during action potential (GO:0086010)2.81046916
120centriole assembly (GO:0098534)2.80804839
121G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.79761230
122detection of calcium ion (GO:0005513)2.78382993
123negative regulation of organelle assembly (GO:1902116)2.77934568
124neuronal action potential (GO:0019228)2.77596632
125NAD biosynthetic process (GO:0009435)2.73609500
126sulfation (GO:0051923)2.72424330
127inner ear receptor stereocilium organization (GO:0060122)2.71970354
128regulation of establishment of cell polarity (GO:2000114)2.70618461
129cell projection assembly (GO:0030031)2.69376702
130UTP metabolic process (GO:0046051)2.68139418
131polyol catabolic process (GO:0046174)2.67438307
132drug catabolic process (GO:0042737)2.67025900
133central nervous system neuron axonogenesis (GO:0021955)2.65873931
134negative regulation of systemic arterial blood pressure (GO:0003085)2.64043874
135guanosine-containing compound biosynthetic process (GO:1901070)2.63704336
136meiotic cell cycle (GO:0051321)2.63582525
137protein K63-linked deubiquitination (GO:0070536)2.62402586
138negative regulation of sodium ion transport (GO:0010766)2.61502581
139UDP-N-acetylglucosamine metabolic process (GO:0006047)2.61322942
140lipid translocation (GO:0034204)2.60752069
141phospholipid translocation (GO:0045332)2.60752069
142regulation of collateral sprouting (GO:0048670)2.59576242
143negative regulation of mast cell activation (GO:0033004)2.58834954
144cAMP biosynthetic process (GO:0006171)2.57560932
145aromatic amino acid family catabolic process (GO:0009074)2.56747542
146spinal cord motor neuron differentiation (GO:0021522)2.55008626
147glycerol ether metabolic process (GO:0006662)2.54821009
148transmission of nerve impulse (GO:0019226)2.53100012
149positive regulation of oligodendrocyte differentiation (GO:0048714)2.52595945
150limb development (GO:0060173)2.52407193
151appendage development (GO:0048736)2.52407193
152peptidyl-glutamic acid modification (GO:0018200)2.51454408
153positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.51182847
154smoothened signaling pathway (GO:0007224)2.49700273
155glutamate secretion (GO:0014047)2.49603140
156adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.49544960
157protein prenylation (GO:0018342)2.46962400
158prenylation (GO:0097354)2.46962400
159flavonoid metabolic process (GO:0009812)2.46397064
160activation of protein kinase A activity (GO:0034199)2.45823576
161positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.45599270
162proline transport (GO:0015824)2.45568707
163seminiferous tubule development (GO:0072520)2.45396877
164regulation of meiosis I (GO:0060631)2.45060862
165regulation of establishment or maintenance of cell polarity (GO:0032878)2.44225227
166multicellular organismal development (GO:0007275)2.44014309
167sphingoid metabolic process (GO:0046519)2.43984268
168photoreceptor cell maintenance (GO:0045494)2.42617544
169regulation of protein kinase A signaling (GO:0010738)2.40400644
170ether metabolic process (GO:0018904)2.39788199
171calcium ion import (GO:0070509)2.39238880
172genitalia morphogenesis (GO:0035112)2.38221389
173regulation of female gonad development (GO:2000194)2.35927056
174nonmotile primary cilium assembly (GO:0035058)2.31060966
175nucleotide phosphorylation (GO:0046939)2.30128167
176microtubule-based transport (GO:0010970)2.27713627
177synaptic vesicle docking involved in exocytosis (GO:0016081)2.23563049
178cilium or flagellum-dependent cell motility (GO:0001539)11.8082521
179axonemal dynein complex assembly (GO:0070286)11.3783266
180cilium movement (GO:0003341)10.1732998

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.48493843
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.50299719
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.14947784
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.87442434
5IGF1R_20145208_ChIP-Seq_DFB_Human2.50092520
6GBX2_23144817_ChIP-Seq_PC3_Human2.29910106
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.08350866
8PIAS1_25552417_ChIP-Seq_VCAP_Human2.07310527
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.04664086
10TAF15_26573619_Chip-Seq_HEK293_Human2.04182869
11SALL1_21062744_ChIP-ChIP_HESCs_Human1.99799687
12FUS_26573619_Chip-Seq_HEK293_Human1.99729083
13EWS_26573619_Chip-Seq_HEK293_Human1.97144097
14REST_21632747_ChIP-Seq_MESCs_Mouse1.86616432
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86558186
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.81172827
17VDR_22108803_ChIP-Seq_LS180_Human1.78496671
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.72599950
19DROSHA_22980978_ChIP-Seq_HELA_Human1.69407284
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68482823
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.67409096
22RNF2_27304074_Chip-Seq_NSC_Mouse1.66033561
23AR_21572438_ChIP-Seq_LNCaP_Human1.61354077
24RBPJ_22232070_ChIP-Seq_NCS_Mouse1.59757652
25AR_25329375_ChIP-Seq_VCAP_Human1.59347374
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57261428
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.56548605
28SMAD4_21799915_ChIP-Seq_A2780_Human1.55704582
29ZNF274_21170338_ChIP-Seq_K562_Hela1.54949184
30GATA1_26923725_Chip-Seq_HPCs_Mouse1.54787158
31KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.51599217
32PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51073695
33MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47088744
34POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.45142987
35TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45142987
36SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.44047859
37EZH2_27294783_Chip-Seq_NPCs_Mouse1.40634083
38SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40555546
39TP53_16413492_ChIP-PET_HCT116_Human1.40174239
40TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.39794469
41OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35586096
42EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.34467811
43ELK4_26923725_Chip-Seq_MESODERM_Mouse1.34149765
44RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33785922
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33232583
46PRDM14_20953172_ChIP-Seq_ESCs_Human1.33002921
47EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32389322
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31265199
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31023139
50AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29828254
51TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29091339
52SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28958341
53KDM2B_26808549_Chip-Seq_REH_Human1.28852294
54TAL1_26923725_Chip-Seq_HPCs_Mouse1.27999488
55KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27109012
56CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25844756
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.25567743
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.25408208
59CBP_20019798_ChIP-Seq_JUKART_Human1.24715835
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24715835
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.23869303
62P300_19829295_ChIP-Seq_ESCs_Human1.23600337
63NANOG_19829295_ChIP-Seq_ESCs_Human1.23534271
64SOX2_19829295_ChIP-Seq_ESCs_Human1.23534271
65EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23102291
66BMI1_23680149_ChIP-Seq_NPCS_Mouse1.22888450
67TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.22780164
68BCAT_22108803_ChIP-Seq_LS180_Human1.22080888
69SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21636104
70CDX2_22108803_ChIP-Seq_LS180_Human1.21578086
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20819426
72RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.20325441
73WDR5_24793694_ChIP-Seq_LNCAP_Human1.19744156
74ARNT_22903824_ChIP-Seq_MCF-7_Human1.19584723
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.19409820
76ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19151497
77NR3C1_21868756_ChIP-Seq_MCF10A_Human1.18240366
78TCF4_23295773_ChIP-Seq_U87_Human1.18165686
79ER_23166858_ChIP-Seq_MCF-7_Human1.17804945
80EZH2_27294783_Chip-Seq_ESCs_Mouse1.17265972
81CRX_20693478_ChIP-Seq_RETINA_Mouse1.16490696
82FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16329731
83FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16312592
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16305119
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16292324
86SMAD4_21741376_ChIP-Seq_EPCs_Human1.16114279
87PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16095934
88P53_22387025_ChIP-Seq_ESCs_Mouse1.16046656
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.15542239
90SOX2_21211035_ChIP-Seq_LN229_Gbm1.13087411
91BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.13057956
92SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.12809269
93MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12286572
94AHR_22903824_ChIP-Seq_MCF-7_Human1.11819507
95STAT3_23295773_ChIP-Seq_U87_Human1.11649098
96CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11202523
97PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10343876
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.09512172
99FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09165766
100TP53_22573176_ChIP-Seq_HFKS_Human1.09061840
101STAT6_21828071_ChIP-Seq_BEAS2B_Human1.08732327
102FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08167660
103IRF1_19129219_ChIP-ChIP_H3396_Human1.08155464
104CMYC_18555785_Chip-Seq_ESCs_Mouse1.07400956
105SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07350355
106CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.06791742
107OCT4_21477851_ChIP-Seq_ESCs_Mouse1.06528436
108NFE2_27457419_Chip-Seq_LIVER_Mouse1.06379342
109SMAD3_21741376_ChIP-Seq_ESCs_Human1.06028502
110SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.05438169
111SMAD_19615063_ChIP-ChIP_OVARY_Human1.05239907
112RXR_22108803_ChIP-Seq_LS180_Human1.05112306
113STAT1_17558387_ChIP-Seq_HELA_Human1.03775740
114RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03266985
115EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.02323026
116TP53_18474530_ChIP-ChIP_U2OS_Human1.01666369
117REST_18959480_ChIP-ChIP_MESCs_Mouse1.01153792
118SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00802656
119RNF2_27304074_Chip-Seq_ESCs_Mouse1.00310416
120UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00246543
121CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99658964
122E2F1_18555785_Chip-Seq_ESCs_Mouse0.99264081
123GF1_26923725_Chip-Seq_HPCs_Mouse0.98179293
124CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96673004
125SOX2_18555785_Chip-Seq_ESCs_Mouse0.96583111
126P300_18555785_Chip-Seq_ESCs_Mouse0.94866668
127OCT4_18555785_Chip-Seq_ESCs_Mouse0.93942171
128SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.93897419
129STAT3_18555785_Chip-Seq_ESCs_Mouse0.93652717
130SOX9_26525672_Chip-Seq_HEART_Mouse0.93620939
131TCF4_22108803_ChIP-Seq_LS180_Human0.93581186
132PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93223564
133RUNX2_22187159_ChIP-Seq_PCA_Human0.93209343
134SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92846254
135CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92683143
136GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.92673723

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.35287702
2MP0001984_abnormal_olfaction8.67429805
3MP0003698_abnormal_male_reproductive3.69344870
4MP0003195_calcinosis3.52403256
5MP0002653_abnormal_ependyma_morphology3.36552691
6MP0001929_abnormal_gametogenesis3.05085188
7MP0008057_abnormal_DNA_replication2.95285875
8MP0008877_abnormal_DNA_methylation2.58397156
9MP0005623_abnormal_meninges_morphology2.30875844
10MP0002210_abnormal_sex_determination2.19398022
11MP0005499_abnormal_olfactory_system2.18075996
12MP0005394_taste/olfaction_phenotype2.18075996
13MP0009046_muscle_twitch2.15416117
14MP0002160_abnormal_reproductive_system2.12762217
15MP0004859_abnormal_synaptic_plasticity2.06654515
16MP0008789_abnormal_olfactory_epithelium2.03120596
17MP0000427_abnormal_hair_cycle2.01503553
18MP0002161_abnormal_fertility/fecundity1.97384198
19MP0003635_abnormal_synaptic_transmissio1.84397576
20MP0000383_abnormal_hair_follicle1.82549598
21MP0004270_analgesia1.79413502
22MP0002837_dystrophic_cardiac_calcinosis1.78932394
23MP0005645_abnormal_hypothalamus_physiol1.77939448
24MP0002734_abnormal_mechanical_nocicepti1.74914691
25MP0001145_abnormal_male_reproductive1.72959981
26MP0003950_abnormal_plasma_membrane1.68480112
27MP0002876_abnormal_thyroid_physiology1.67578978
28MP0002184_abnormal_innervation1.65934075
29MP0003880_abnormal_central_pattern1.65920703
30MP0005551_abnormal_eye_electrophysiolog1.59845635
31MP0008872_abnormal_physiological_respon1.58510745
32MP0001485_abnormal_pinna_reflex1.57281605
33MP0000653_abnormal_sex_gland1.55122149
34MP0002272_abnormal_nervous_system1.54562743
35MP0002638_abnormal_pupillary_reflex1.52542705
36MP0004145_abnormal_muscle_electrophysio1.50378449
37MP0004142_abnormal_muscle_tone1.49200676
38MP0001486_abnormal_startle_reflex1.47390444
39MP0002063_abnormal_learning/memory/cond1.46491206
40MP0005174_abnormal_tail_pigmentation1.46395865
41MP0005423_abnormal_somatic_nervous1.46127105
42MP0009745_abnormal_behavioral_response1.43471782
43MP0002572_abnormal_emotion/affect_behav1.40106745
44MP0010386_abnormal_urinary_bladder1.40022332
45MP0003045_fibrosis1.38808619
46MP0002557_abnormal_social/conspecific_i1.38520306
47MP0002064_seizures1.35599894
48MP0002938_white_spotting1.34785239
49MP0003252_abnormal_bile_duct1.34269492
50MP0001968_abnormal_touch/_nociception1.33791095
51MP0003787_abnormal_imprinting1.33312034
52MP0004147_increased_porphyrin_level1.32630501
53MP0005310_abnormal_salivary_gland1.31119640
54MP0000778_abnormal_nervous_system1.27260314
55MP0003890_abnormal_embryonic-extraembry1.25925864
56MP0005377_hearing/vestibular/ear_phenot1.25149888
57MP0003878_abnormal_ear_physiology1.25149888
58MP0001986_abnormal_taste_sensitivity1.23530121
59MP0008875_abnormal_xenobiotic_pharmacok1.23370813
60MP0002168_other_aberrant_phenotype1.23350003
61MP0002928_abnormal_bile_duct1.21870233
62MP0005085_abnormal_gallbladder_physiolo1.18901793
63MP0005646_abnormal_pituitary_gland1.18588103
64MP0002882_abnormal_neuron_morphology1.15555899
65MP0002752_abnormal_somatic_nervous1.15479805
66MP0004215_abnormal_myocardial_fiber1.12938085
67MP0000230_abnormal_systemic_arterial1.11327713
68MP0004742_abnormal_vestibular_system1.11099086
69MP0002234_abnormal_pharynx_morphology1.10002293
70MP0002067_abnormal_sensory_capabilities1.08589257
71MP0002138_abnormal_hepatobiliary_system1.06656027
72MP0005389_reproductive_system_phenotype1.06362141
73MP0004811_abnormal_neuron_physiology1.05977269
74MP0003879_abnormal_hair_cell1.05880912
75MP0005171_absent_coat_pigmentation1.05637236
76MP0002735_abnormal_chemical_nociception1.03712775
77MP0002736_abnormal_nociception_after1.03635355
78MP0005670_abnormal_white_adipose1.02986594
79MP0002822_catalepsy1.01455674
80MP0004133_heterotaxia1.00189313
81MP0000569_abnormal_digit_pigmentation0.99902506
82MP0002152_abnormal_brain_morphology0.99472227
83MP0001501_abnormal_sleep_pattern0.98115851
84MP0003718_maternal_effect0.96693196
85MP0005395_other_phenotype0.95747572
86MP0010678_abnormal_skin_adnexa0.94839971
87MP0008961_abnormal_basal_metabolism0.94677472
88MP0005167_abnormal_blood-brain_barrier0.94585786
89MP0000538_abnormal_urinary_bladder0.94419086
90MP0004885_abnormal_endolymph0.93405711
91MP0002282_abnormal_trachea_morphology0.92649230
92MP0006292_abnormal_olfactory_placode0.92628521
93MP0001970_abnormal_pain_threshold0.92610630
94MP0001440_abnormal_grooming_behavior0.92369775
95MP0002229_neurodegeneration0.91805652
96MP0006276_abnormal_autonomic_nervous0.91471847
97MP0002909_abnormal_adrenal_gland0.90392347
98MP0002095_abnormal_skin_pigmentation0.89400923
99MP0001765_abnormal_ion_homeostasis0.87572754
100MP0003937_abnormal_limbs/digits/tail_de0.86268776
101MP0000371_diluted_coat_color0.84496919
102MP0003137_abnormal_impulse_conducting0.83305006
103MP0004085_abnormal_heartbeat0.82928788
104MP0003634_abnormal_glial_cell0.81456744
105MP0006054_spinal_hemorrhage0.81382031
106MP0004233_abnormal_muscle_weight0.80301608
107MP0004130_abnormal_muscle_cell0.78808707
108MP0003633_abnormal_nervous_system0.78662589
109MP0001324_abnormal_eye_pigmentation0.77450461
110MP0000631_abnormal_neuroendocrine_gland0.76558650
111MP0000955_abnormal_spinal_cord0.75223456
112MP0005187_abnormal_penis_morphology0.74691380
113MP0002233_abnormal_nose_morphology0.72323446
114MP0005266_abnormal_metabolism0.71898716
115MP0001963_abnormal_hearing_physiology0.71062712
116MP0003861_abnormal_nervous_system0.70660474
117MP0008569_lethality_at_weaning0.69782628
118MP0005195_abnormal_posterior_eye0.69306594
119MP0005084_abnormal_gallbladder_morpholo0.69163213
120MP0003646_muscle_fatigue0.68694019
121MP0000534_abnormal_ureter_morphology0.66296614
122MP0002066_abnormal_motor_capabilities/c0.64682616
123MP0002733_abnormal_thermal_nociception0.64294352
124MP0003942_abnormal_urinary_system0.64032003
125MP0001188_hyperpigmentation0.63904860
126MP0005253_abnormal_eye_physiology0.62789506
127MP0001299_abnormal_eye_distance/0.61288363
128MP0000026_abnormal_inner_ear0.59223422
129MP0000013_abnormal_adipose_tissue0.59032761
130MP0003136_yellow_coat_color0.58528144
131MP0001502_abnormal_circadian_rhythm0.58084041
132MP0005367_renal/urinary_system_phenotyp0.57495495
133MP0000516_abnormal_urinary_system0.57495495
134MP0002102_abnormal_ear_morphology0.56935476
135MP0003631_nervous_system_phenotype0.56562561
136MP0006072_abnormal_retinal_apoptosis0.55647711
137MP0004858_abnormal_nervous_system0.54688411
138MP0001542_abnormal_bone_strength0.53066450
139MP0001293_anophthalmia0.52376093
140MP0004924_abnormal_behavior0.51576285
141MP0005386_behavior/neurological_phenoty0.51576285
142MP0003329_amyloid_beta_deposits0.51546778
143MP0009780_abnormal_chondrocyte_physiolo0.50816804
144MP0001177_atelectasis0.49844387
145MP0005391_vision/eye_phenotype0.48711002
146MP0008995_early_reproductive_senescence0.45572202
147MP0000372_irregular_coat_pigmentation0.45345721
148MP0004043_abnormal_pH_regulation0.44884202

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)9.90652080
2Absent/shortened dynein arms (HP:0200106)9.90652080
3Abnormal ciliary motility (HP:0012262)8.74071053
4Abnormal respiratory motile cilium morphology (HP:0005938)8.51640077
5Abnormal respiratory epithelium morphology (HP:0012253)8.51640077
6Rhinitis (HP:0012384)8.31497032
7Chronic bronchitis (HP:0004469)7.02510047
8Bronchiectasis (HP:0002110)4.60886879
9Nasal polyposis (HP:0100582)4.50088801
10Infertility (HP:0000789)4.36630534
11Nephronophthisis (HP:0000090)4.28876011
12Abnormality of midbrain morphology (HP:0002418)3.86276069
13Molar tooth sign on MRI (HP:0002419)3.86276069
14Genetic anticipation (HP:0003743)3.86041776
15Medial flaring of the eyebrow (HP:0010747)3.68397190
16Abnormality of the nasal mucosa (HP:0000433)3.57986692
17Bronchitis (HP:0012387)3.49185059
18Congenital stationary night blindness (HP:0007642)3.36632760
19Abnormality of the renal medulla (HP:0100957)3.35201315
20Gait imbalance (HP:0002141)3.17994772
21Attenuation of retinal blood vessels (HP:0007843)3.15712235
22Congenital primary aphakia (HP:0007707)3.11323917
23Abnormality of macular pigmentation (HP:0008002)3.00797297
24Pancreatic fibrosis (HP:0100732)2.97518729
25Recurrent sinusitis (HP:0011108)2.86607454
26Protruding tongue (HP:0010808)2.83262973
27Tubulointerstitial nephritis (HP:0001970)2.83227540
28Nephrogenic diabetes insipidus (HP:0009806)2.82518358
29Recurrent otitis media (HP:0000403)2.80066450
30True hermaphroditism (HP:0010459)2.79010540
31Aplasia/Hypoplasia of the tibia (HP:0005772)2.76191968
32Retinal dysplasia (HP:0007973)2.72437530
33Decreased circulating renin level (HP:0003351)2.58025050
34Type II lissencephaly (HP:0007260)2.55654187
35Abnormality of dentin (HP:0010299)2.53458965
36Clumsiness (HP:0002312)2.52807198
37Genital tract atresia (HP:0001827)2.52397919
38Fair hair (HP:0002286)2.52295664
39Absent speech (HP:0001344)2.51307917
40Vaginal atresia (HP:0000148)2.46750135
41Furrowed tongue (HP:0000221)2.46498998
42Broad-based gait (HP:0002136)2.45372142
43Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.41321952
44Postaxial hand polydactyly (HP:0001162)2.40556194
45Cystic liver disease (HP:0006706)2.38704368
46Poor coordination (HP:0002370)2.36479235
47Chronic hepatic failure (HP:0100626)2.35506812
48Postaxial foot polydactyly (HP:0001830)2.31479985
49Congenital sensorineural hearing impairment (HP:0008527)2.30453152
50Large for gestational age (HP:0001520)2.28117231
51Inability to walk (HP:0002540)2.26410392
52Keratoconus (HP:0000563)2.24496214
53Increased corneal curvature (HP:0100692)2.24496214
54Tubular atrophy (HP:0000092)2.24173707
55Congenital hepatic fibrosis (HP:0002612)2.23001972
56Focal motor seizures (HP:0011153)2.22569541
57Dialeptic seizures (HP:0011146)2.21929333
58Bifid tongue (HP:0010297)2.21279918
59Occipital encephalocele (HP:0002085)2.19789985
60Cerebellar dysplasia (HP:0007033)2.19155392
61Aplasia/Hypoplasia of the lens (HP:0008063)2.19012937
62Progressive inability to walk (HP:0002505)2.16324289
63Aplasia/Hypoplasia of the tongue (HP:0010295)2.15409538
64Abnormal rod and cone electroretinograms (HP:0008323)2.13335060
65Oculomotor apraxia (HP:0000657)2.12778359
66Pancreatic cysts (HP:0001737)2.12346274
67Chronic sinusitis (HP:0011109)2.11316013
68Tubulointerstitial abnormality (HP:0001969)2.11292936
69Increased neuronal autofluorescent lipopigment (HP:0002074)2.11236344
70Abnormality of the dental root (HP:0006486)2.09492786
71Taurodontia (HP:0000679)2.09492786
72Abnormality of permanent molar morphology (HP:0011071)2.09492786
73Stage 5 chronic kidney disease (HP:0003774)2.07967579
74Median cleft lip (HP:0000161)2.00766904
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8403267
76Abnormal respiratory motile cilium physiology (HP:0012261)10.1129605
77Abnormality of molar morphology (HP:0011070)1.97959317
78Abnormality of molar (HP:0011077)1.97959317
79Abnormality of the dental pulp (HP:0006479)1.97334063
80Widely spaced teeth (HP:0000687)1.97262681
81Atonic seizures (HP:0010819)1.96240816
82Generalized hypopigmentation of hair (HP:0011358)1.96178025
83Renal cortical cysts (HP:0000803)1.95544586
84Polyuria (HP:0000103)1.95075035
85Abnormality of alanine metabolism (HP:0010916)1.94926357
86Hyperalaninemia (HP:0003348)1.94926357
87Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.94926357
88Male infertility (HP:0003251)1.92585705
89Abnormality of the lower motor neuron (HP:0002366)1.90502159
90Hypothermia (HP:0002045)1.90016903
91Absence seizures (HP:0002121)1.88761603
92Absent rod-and cone-mediated responses on ERG (HP:0007688)1.87902850
93Short foot (HP:0001773)1.87571198
94Bony spicule pigmentary retinopathy (HP:0007737)1.86631724
95Fibular hypoplasia (HP:0003038)1.84662704
96Abnormality of the pons (HP:0007361)1.84437725
97Preaxial foot polydactyly (HP:0001841)1.84148179
98Short nail (HP:0001799)1.83643139
99Hypoplastic ischia (HP:0003175)1.82244785
100Lissencephaly (HP:0001339)1.81544305
101Hypoplasia of the pons (HP:0012110)1.80449634
102Small hand (HP:0200055)1.78920182
103Hemiparesis (HP:0001269)1.78224957
104Thyroid-stimulating hormone excess (HP:0002925)1.77011962
105Intestinal atresia (HP:0011100)1.76480617
106Scotoma (HP:0000575)1.75873883
107Highly arched eyebrow (HP:0002553)1.75059172
108Polydipsia (HP:0001959)1.71300895
109Abnormal drinking behavior (HP:0030082)1.71300895
110Facial cleft (HP:0002006)1.66223248
111Abnormal biliary tract physiology (HP:0012439)1.64029374
112Bile duct proliferation (HP:0001408)1.64029374
113Limb dystonia (HP:0002451)1.63509556
114Central scotoma (HP:0000603)1.63123807
115Bell-shaped thorax (HP:0001591)1.58180672
116Febrile seizures (HP:0002373)1.58110181
117Myokymia (HP:0002411)1.56802607
118Dyschromatopsia (HP:0007641)1.56480341
119Retinitis pigmentosa (HP:0000510)1.56312263
120Tubulointerstitial fibrosis (HP:0005576)1.55455142
121Abolished electroretinogram (ERG) (HP:0000550)1.54349658
122Anencephaly (HP:0002323)1.52039279
123Specific learning disability (HP:0001328)1.51130446
124Abnormality of the renal cortex (HP:0011035)1.49236145
125Abnormality of renal excretion (HP:0011036)1.48688644
126Decreased central vision (HP:0007663)1.48294095
127Progressive cerebellar ataxia (HP:0002073)1.47641545
128Focal seizures (HP:0007359)1.46749456
129Epileptic encephalopathy (HP:0200134)1.45854468
130Gaze-evoked nystagmus (HP:0000640)1.42966058
131Anosmia (HP:0000458)1.41643270
132Sclerocornea (HP:0000647)1.40965810
133Supernumerary spleens (HP:0009799)1.40569382
134Absent eyebrow (HP:0002223)1.39254635
135Hyperventilation (HP:0002883)1.38214690
136Constricted visual fields (HP:0001133)1.36826239
137Sensory axonal neuropathy (HP:0003390)1.34973553
138Microglossia (HP:0000171)1.33913302
139Short ribs (HP:0000773)1.31046862
140Gonadotropin excess (HP:0000837)1.30994946
141Hypodontia (HP:0000668)1.30411572
142Male pseudohermaphroditism (HP:0000037)1.30407518
143Renal dysplasia (HP:0000110)1.30117719
144Preaxial hand polydactyly (HP:0001177)1.28286212
145Aplasia/Hypoplasia of the fibula (HP:0006492)1.26938745
146Dental crowding (HP:0000678)1.25377949

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.00759935
2PDK47.00759935
3PDK24.40881206
4PRKD33.26023093
5TESK13.19609619
6ACVR1B3.13423289
7BMPR1B2.98459232
8PNCK2.93809748
9MAPK152.89882990
10ICK2.73804489
11ADRBK22.65447702
12STK392.27783679
13PTK2B2.26603026
14WNK42.17467022
15PHKG21.94258184
16PHKG11.94258184
17MKNK21.88964573
18GRK11.87564765
19TAOK31.77504007
20STK381.68643503
21INSRR1.65273462
22ZAK1.61789266
23MAP3K41.56314428
24MAP4K21.50797531
25MAP2K71.44997848
26PAK31.29624394
27CASK1.28776072
28NTRK21.26708970
29LATS11.22420908
30WNK11.18516828
31ADRBK11.18360057
32ERBB31.17337449
33NTRK31.15134629
34PIK3CG1.12837786
35DAPK21.10729162
36MARK11.09417384
37TGFBR11.07683155
38AKT31.06441495
39MINK11.04294868
40CAMK2B1.00127828
41CAMK2D0.99877594
42DYRK1B0.99132288
43CAMK1G0.97188530
44PRKCG0.95761847
45BRSK20.95686581
46FRK0.95111125
47NLK0.91566686
48TEC0.84848994
49MKNK10.84031902
50STK38L0.83250280
51CAMK2G0.77046819
52TYRO30.76983420
53TNK20.76577318
54PAK60.75600194
55TXK0.75225478
56IRAK10.74180028
57TRPM70.74116731
58ARAF0.73172853
59NUAK10.72319574
60PLK20.71054342
61PRKAA20.68886419
62PINK10.68004311
63CAMKK10.67936565
64TLK10.67429834
65SGK4940.66700203
66SGK2230.66700203
67MAP2K40.66614641
68PDK10.66492036
69CAMK2A0.65796711
70PIK3CA0.65442423
71MAP3K70.64697303
72BRAF0.62749870
73TRIM280.62627988
74GRK50.62259166
75LMTK20.60863699
76MAPKAPK30.60182981
77FGFR20.59909543
78OBSCN0.59187763
79CSNK1A1L0.59034542
80SGK20.57357860
81MAPK130.57243031
82IRAK20.56711489
83MAP3K20.54436739
84EPHA40.54238280
85CSNK1G20.53507719
86MELK0.52965784
87TTK0.51799973
88OXSR10.51092925
89EEF2K0.50905367
90CAMK1D0.50506690
91CDK50.50299363
92BCR0.50107513
93FER0.48188879
94PKN10.47736509
95ERBB20.46907457
96PLK40.46786733
97RPS6KA20.44905824
98EIF2AK30.44210477
99WEE10.43665445
100CAMKK20.43112812
101STK110.42465510
102SGK30.42459806
103DAPK10.42072817
104MAPKAPK50.41775134
105CDK30.41471914
106MAP3K90.40004429
107CHUK0.39410734
108NEK20.38695899
109CSNK1G30.38471503
110EPHA30.37618254
111MAP2K60.36748288
112MARK20.35799091
113KIT0.35573537
114PRKCQ0.34509815
115PDPK10.33711051
116PRKAA10.33663686
117SGK10.33301756
118IKBKB0.33023695
119ITK0.32932748
120CSNK1D0.30973836
121STK30.29521570
122BRD40.29392676
123MARK30.29184542
124CAMK40.29012119
125WNK30.28890425
126TIE10.28074840
127DYRK30.27608660
128PRKCZ0.27056249
129RPS6KB10.26969880
130PRKG10.26748451
131DYRK1A0.26557752
132TNIK0.25108480
133NTRK10.23215201
134NEK60.22667538
135CCNB10.22535899
136MAPK100.20695106
137PRKCE0.20625631
138MST40.20493409
139CDK140.20463342
140PRKACA0.18064415
141PRKCB0.17572602
142CSNK1G10.17500888
143SIK20.17140295
144RPS6KA30.15455377
145CAMK10.15000640
146MUSK0.14789561
147CDK180.14571201
148PRKCA0.14256037

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047406.84595385
2Butanoate metabolism_Homo sapiens_hsa006502.80495099
3Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.64242901
4Phototransduction_Homo sapiens_hsa047442.48382577
5Tryptophan metabolism_Homo sapiens_hsa003802.35971200
6Synaptic vesicle cycle_Homo sapiens_hsa047212.28856067
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.22720690
8Nitrogen metabolism_Homo sapiens_hsa009102.20718495
9Amphetamine addiction_Homo sapiens_hsa050312.16420565
10Circadian entrainment_Homo sapiens_hsa047132.08240865
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.05482265
12Fatty acid biosynthesis_Homo sapiens_hsa000612.04892952
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.03322804
14Insulin secretion_Homo sapiens_hsa049112.01264386
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.98888583
16Taste transduction_Homo sapiens_hsa047421.96129434
17Pyruvate metabolism_Homo sapiens_hsa006201.86437631
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.86083225
19Nicotine addiction_Homo sapiens_hsa050331.77102553
20Morphine addiction_Homo sapiens_hsa050321.74982566
21Collecting duct acid secretion_Homo sapiens_hsa049661.74759997
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.74755686
23Glucagon signaling pathway_Homo sapiens_hsa049221.73338589
24Glutamatergic synapse_Homo sapiens_hsa047241.73126265
25Gastric acid secretion_Homo sapiens_hsa049711.72264076
26Long-term potentiation_Homo sapiens_hsa047201.67057903
27Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.63429236
28Salivary secretion_Homo sapiens_hsa049701.62257173
29Homologous recombination_Homo sapiens_hsa034401.61698978
30Renin secretion_Homo sapiens_hsa049241.60826707
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.60566880
32Dopaminergic synapse_Homo sapiens_hsa047281.60297224
33Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.59920310
34GABAergic synapse_Homo sapiens_hsa047271.59691113
35Histidine metabolism_Homo sapiens_hsa003401.57533933
36Chemical carcinogenesis_Homo sapiens_hsa052041.57365733
37Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.54108841
38Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49870800
39Dorso-ventral axis formation_Homo sapiens_hsa043201.47315358
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.47149525
41Retinol metabolism_Homo sapiens_hsa008301.46458924
42Fanconi anemia pathway_Homo sapiens_hsa034601.46144923
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.39666425
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.37687757
45Calcium signaling pathway_Homo sapiens_hsa040201.36992017
46Oocyte meiosis_Homo sapiens_hsa041141.35550964
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.34756828
48Caffeine metabolism_Homo sapiens_hsa002321.34476128
49Vitamin B6 metabolism_Homo sapiens_hsa007501.34202986
50Selenocompound metabolism_Homo sapiens_hsa004501.34156933
51Vibrio cholerae infection_Homo sapiens_hsa051101.33024941
52beta-Alanine metabolism_Homo sapiens_hsa004101.31756535
53Huntingtons disease_Homo sapiens_hsa050161.29899855
54cAMP signaling pathway_Homo sapiens_hsa040241.28812276
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.22427232
56cGMP-PKG signaling pathway_Homo sapiens_hsa040221.18720844
57Thyroid hormone synthesis_Homo sapiens_hsa049181.16649312
58Estrogen signaling pathway_Homo sapiens_hsa049151.16209556
59Cardiac muscle contraction_Homo sapiens_hsa042601.13940724
60Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.12889256
61Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.09729162
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09407305
63Cholinergic synapse_Homo sapiens_hsa047251.05853425
64Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.03102847
65Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01494147
66Arachidonic acid metabolism_Homo sapiens_hsa005901.00688328
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00496730
68Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00495904
69Mineral absorption_Homo sapiens_hsa049781.00460173
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96057800
71Propanoate metabolism_Homo sapiens_hsa006400.95969698
72Bile secretion_Homo sapiens_hsa049760.91692127
73Cocaine addiction_Homo sapiens_hsa050300.89824309
74Oxytocin signaling pathway_Homo sapiens_hsa049210.89684657
75Ovarian steroidogenesis_Homo sapiens_hsa049130.87222974
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.86026178
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.85690510
78Peroxisome_Homo sapiens_hsa041460.84233390
79Circadian rhythm_Homo sapiens_hsa047100.82934443
80Lysine degradation_Homo sapiens_hsa003100.82256429
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81727629
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.81700329
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.81554829
84Fatty acid degradation_Homo sapiens_hsa000710.80700326
85Melanogenesis_Homo sapiens_hsa049160.77110994
86Alcoholism_Homo sapiens_hsa050340.76813604
87Serotonergic synapse_Homo sapiens_hsa047260.76340987
88Pancreatic secretion_Homo sapiens_hsa049720.75847374
89Long-term depression_Homo sapiens_hsa047300.71425855
90GnRH signaling pathway_Homo sapiens_hsa049120.68463032
91Regulation of autophagy_Homo sapiens_hsa041400.68358651
92Axon guidance_Homo sapiens_hsa043600.64973637
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.63027810
94Glycerolipid metabolism_Homo sapiens_hsa005610.63010434
95Gap junction_Homo sapiens_hsa045400.60728859
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60271262
97Sphingolipid metabolism_Homo sapiens_hsa006000.59130306
98Non-homologous end-joining_Homo sapiens_hsa034500.59103694
99Hedgehog signaling pathway_Homo sapiens_hsa043400.55734519
100RNA polymerase_Homo sapiens_hsa030200.54953175
101Inositol phosphate metabolism_Homo sapiens_hsa005620.54376891
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52805878
103One carbon pool by folate_Homo sapiens_hsa006700.52752099
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50866426
105Linoleic acid metabolism_Homo sapiens_hsa005910.50831226
106ABC transporters_Homo sapiens_hsa020100.50732027
107Alzheimers disease_Homo sapiens_hsa050100.50531425
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49910879
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49356088
110Oxidative phosphorylation_Homo sapiens_hsa001900.48746038
111Asthma_Homo sapiens_hsa053100.48423010
112Ether lipid metabolism_Homo sapiens_hsa005650.47938128
113Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45482441
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.44006603
115Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.42134081
116Purine metabolism_Homo sapiens_hsa002300.41254254
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40786230
118Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40230049
119Graft-versus-host disease_Homo sapiens_hsa053320.39968870
120Basal transcription factors_Homo sapiens_hsa030220.39913603
121Type II diabetes mellitus_Homo sapiens_hsa049300.39488051
122Parkinsons disease_Homo sapiens_hsa050120.38727253
123Wnt signaling pathway_Homo sapiens_hsa043100.38646854
124Protein export_Homo sapiens_hsa030600.38600914
125RNA degradation_Homo sapiens_hsa030180.36410811
126Fatty acid metabolism_Homo sapiens_hsa012120.35440930
127Fat digestion and absorption_Homo sapiens_hsa049750.35139951
128PPAR signaling pathway_Homo sapiens_hsa033200.35080741
129Dilated cardiomyopathy_Homo sapiens_hsa054140.34607150
130N-Glycan biosynthesis_Homo sapiens_hsa005100.34331514
131Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.33729496
132Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.32699534
133Vitamin digestion and absorption_Homo sapiens_hsa049770.32595224
134Metabolic pathways_Homo sapiens_hsa011000.32551082
135Glioma_Homo sapiens_hsa052140.32205768
136Endocytosis_Homo sapiens_hsa041440.31233045
137Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.30948914
138Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30494555
139Sulfur metabolism_Homo sapiens_hsa009200.30240697
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30130784
141Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29287495
142TGF-beta signaling pathway_Homo sapiens_hsa043500.28594451
143MAPK signaling pathway_Homo sapiens_hsa040100.28118566
144Ras signaling pathway_Homo sapiens_hsa040140.26995081
145Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26305891
146Insulin signaling pathway_Homo sapiens_hsa049100.26072459
147Glycosaminoglycan degradation_Homo sapiens_hsa005310.25590175
148Tight junction_Homo sapiens_hsa045300.24541560
149Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24235736

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