CFAP70

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.88549538
2cell wall macromolecule catabolic process (GO:0016998)9.81315022
3cell wall macromolecule metabolic process (GO:0044036)9.81315022
4piRNA metabolic process (GO:0034587)9.67028579
5motile cilium assembly (GO:0044458)9.59366678
6binding of sperm to zona pellucida (GO:0007339)9.57105566
7cell-cell recognition (GO:0009988)9.53812898
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.53029767
9acrosome reaction (GO:0007340)9.39888346
10reproduction (GO:0000003)8.82990497
11male meiosis (GO:0007140)8.63622177
12spermatid development (GO:0007286)8.32944956
13regulation of cilium movement (GO:0003352)8.13860748
14synaptonemal complex organization (GO:0070193)7.71835888
15single fertilization (GO:0007338)7.32891323
16synaptonemal complex assembly (GO:0007130)7.24577066
17ventricular system development (GO:0021591)6.77002334
18sperm capacitation (GO:0048240)6.60845185
19fertilization (GO:0009566)6.19401061
20DNA methylation involved in gamete generation (GO:0043046)6.13021796
21axoneme assembly (GO:0035082)5.90185844
22male meiosis I (GO:0007141)5.75959582
23vitamin transmembrane transport (GO:0035461)5.63978627
24spermatogenesis (GO:0007283)5.54020094
25male gamete generation (GO:0048232)5.52004434
26negative regulation of inclusion body assembly (GO:0090084)5.39427528
27primary alcohol catabolic process (GO:0034310)5.36653223
28chromosome organization involved in meiosis (GO:0070192)5.16403370
29diterpenoid biosynthetic process (GO:0016102)5.10627067
30gamete generation (GO:0007276)5.08414177
31GTP biosynthetic process (GO:0006183)5.04890377
32microtubule severing (GO:0051013)5.04606101
33intraciliary transport (GO:0042073)4.92755608
34cellular process involved in reproduction in multicellular organism (GO:0022412)4.92543241
35meiotic nuclear division (GO:0007126)4.90146445
36ethanol metabolic process (GO:0006067)4.84771795
37nucleoside diphosphate phosphorylation (GO:0006165)4.83394545
38germ cell development (GO:0007281)4.81745813
39regulation of microtubule-based movement (GO:0060632)4.72593282
40cell recognition (GO:0008037)4.71230840
41microtubule depolymerization (GO:0007019)4.65415685
42protein localization to cilium (GO:0061512)4.64677269
43meiosis I (GO:0007127)4.58968449
44UTP biosynthetic process (GO:0006228)4.51210267
45meiotic cell cycle (GO:0051321)4.43947827
46seminiferous tubule development (GO:0072520)4.43376735
47cell projection assembly (GO:0030031)4.42689355
48organic cation transport (GO:0015695)4.42479583
49calcium ion-dependent exocytosis (GO:0017156)4.40096363
50regulation of inclusion body assembly (GO:0090083)4.40034403
51protein polyglutamylation (GO:0018095)4.35502109
52response to xenobiotic stimulus (GO:0009410)4.31425172
53lateral ventricle development (GO:0021670)4.20733673
54left/right pattern formation (GO:0060972)4.11645660
55pyrimidine-containing compound transmembrane transport (GO:0072531)4.10636463
56regulation of interleukin-5 production (GO:0032674)4.09942662
57spermatid nucleus differentiation (GO:0007289)4.07668187
58UTP metabolic process (GO:0046051)4.07276879
59cilium organization (GO:0044782)4.04184845
60multicellular organismal reproductive process (GO:0048609)4.00079350
61microtubule-based movement (GO:0007018)3.99195143
62one-carbon compound transport (GO:0019755)3.99097247
63monoubiquitinated protein deubiquitination (GO:0035520)3.87570809
64cilium assembly (GO:0042384)3.81759050
65lung epithelium development (GO:0060428)3.79981625
66negative regulation of humoral immune response (GO:0002921)3.76569597
67negative regulation of B cell mediated immunity (GO:0002713)3.71328674
68negative regulation of immunoglobulin mediated immune response (GO:0002890)3.71328674
69cilium morphogenesis (GO:0060271)3.68604260
70left/right axis specification (GO:0070986)3.68082847
71cellular component assembly involved in morphogenesis (GO:0010927)3.66118549
72cytoplasmic microtubule organization (GO:0031122)3.63738861
73genitalia morphogenesis (GO:0035112)3.61594784
74negative regulation of T cell differentiation in thymus (GO:0033085)3.59502045
75determination of left/right symmetry (GO:0007368)3.54108747
76glomerular epithelial cell development (GO:0072310)3.53036124
77terpenoid biosynthetic process (GO:0016114)3.52914630
78tolerance induction (GO:0002507)3.52362730
79gene silencing by RNA (GO:0031047)3.52312827
80guanosine-containing compound biosynthetic process (GO:1901070)3.51628929
81retinoic acid metabolic process (GO:0042573)3.47853405
82ethanol oxidation (GO:0006069)3.47368187
83chaperone-mediated protein complex assembly (GO:0051131)3.46683007
84centriole assembly (GO:0098534)3.46186331
85centriole replication (GO:0007099)3.44950071
86regulation of centriole replication (GO:0046599)3.44493270
87regulation of interleukin-13 production (GO:0032656)3.42703496
88determination of bilateral symmetry (GO:0009855)3.41388168
89regulation of germinal center formation (GO:0002634)3.36493939
90CTP biosynthetic process (GO:0006241)3.35090511
91CTP metabolic process (GO:0046036)3.35090511
92specification of symmetry (GO:0009799)3.33639253
93negative regulation of organelle assembly (GO:1902116)3.31324462
94microtubule polymerization or depolymerization (GO:0031109)3.29421429
95establishment of apical/basal cell polarity (GO:0035089)3.29126179
96exogenous drug catabolic process (GO:0042738)3.28976509
97smoothened signaling pathway (GO:0007224)3.22981834
98multicellular organismal development (GO:0007275)3.18180692
99pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.17685771
100synapsis (GO:0007129)3.15666156
101photoreceptor cell maintenance (GO:0045494)3.14464381
102pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.07045088
103meiotic cell cycle process (GO:1903046)3.06302183
104regulation of meiosis I (GO:0060631)3.03165793
105retinal rod cell development (GO:0046548)3.03149830
106lactate metabolic process (GO:0006089)3.02945431
107microtubule bundle formation (GO:0001578)2.99868678
108establishment or maintenance of monopolar cell polarity (GO:0061339)2.99475607
109establishment of monopolar cell polarity (GO:0061162)2.99475607
110alditol metabolic process (GO:0019400)2.93095911
111microtubule-based process (GO:0007017)2.91693568
112positive regulation of smoothened signaling pathway (GO:0045880)2.89963978
113glutathione derivative metabolic process (GO:1901685)2.89596675
114glutathione derivative biosynthetic process (GO:1901687)2.89596675
115organelle assembly (GO:0070925)2.89115888
116regulation of protein polyubiquitination (GO:1902914)2.86055651
117nonmotile primary cilium assembly (GO:0035058)2.85106949
118retinol metabolic process (GO:0042572)2.84292264
119pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.83105371
120regulation of chromatin binding (GO:0035561)2.82787129
121O-glycan processing (GO:0016266)2.82061790
122carnitine transport (GO:0015879)2.82005082
123amino-acid betaine transport (GO:0015838)2.82005082
124carnitine transmembrane transport (GO:1902603)2.81845641
125drug catabolic process (GO:0042737)2.81338130
126polyol catabolic process (GO:0046174)2.79453607
127primary alcohol metabolic process (GO:0034308)2.79438206
128glycerol ether metabolic process (GO:0006662)2.78639504
129retinal cone cell development (GO:0046549)2.76604070
130pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.75501009
131establishment of tissue polarity (GO:0007164)2.74356556
132establishment of planar polarity (GO:0001736)2.74356556
133positive regulation of tolerance induction (GO:0002645)2.73454673
134regulation of spindle checkpoint (GO:0090231)2.73097169
135carnitine metabolic process (GO:0009437)2.71578557
136glycerol metabolic process (GO:0006071)2.66346618
137peptidyl-glutamic acid modification (GO:0018200)2.64486608
138ether metabolic process (GO:0018904)2.58680432
139protein K11-linked deubiquitination (GO:0035871)2.56246057
140nucleotide phosphorylation (GO:0046939)2.55862889
141negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.53959009
142phosphatidylcholine biosynthetic process (GO:0006656)2.53123687
143quaternary ammonium group transport (GO:0015697)2.52835645
144heart looping (GO:0001947)2.51530307
145aldehyde catabolic process (GO:0046185)2.51164990
146regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.49282829
147phosphatidylethanolamine biosynthetic process (GO:0006646)2.49192575
148intra-S DNA damage checkpoint (GO:0031573)2.46464125
149hydrogen peroxide biosynthetic process (GO:0050665)2.46065108
150CDP-diacylglycerol biosynthetic process (GO:0016024)2.45998227
151iron ion import (GO:0097286)2.45156651
152regulation of autophagic vacuole assembly (GO:2000785)2.42843675
153lateral sprouting from an epithelium (GO:0060601)2.42783062
154apical protein localization (GO:0045176)2.42262862
155excretion (GO:0007588)2.40520302
156phosphatidylethanolamine metabolic process (GO:0046337)2.34603780
157regulation of microtubule depolymerization (GO:0031114)2.29281688
158regulation of smoothened signaling pathway (GO:0008589)2.28514296
159cilium or flagellum-dependent cell motility (GO:0001539)17.0314508
160fusion of sperm to egg plasma membrane (GO:0007342)12.9928618
161axonemal dynein complex assembly (GO:0070286)12.3537630
162acrosome assembly (GO:0001675)11.5253890
163sperm motility (GO:0030317)11.0759234
164multicellular organism reproduction (GO:0032504)11.0450715
165cilium movement (GO:0003341)10.9683844
166epithelial cilium movement (GO:0003351)10.7952778
167sperm-egg recognition (GO:0035036)10.6741472

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.67269887
2EZH2_22144423_ChIP-Seq_EOC_Human5.27134206
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.89497035
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.92071953
5DROSHA_22980978_ChIP-Seq_HELA_Human3.10918072
6FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.84608960
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.73221750
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.62266937
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.55129657
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.53886574
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.49143876
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.38141299
13PIAS1_25552417_ChIP-Seq_VCAP_Human2.35465933
14PCGF2_27294783_Chip-Seq_NPCs_Mouse2.07253189
15EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.05663512
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.98584649
17AHR_22903824_ChIP-Seq_MCF-7_Human1.97192983
18ESR1_20079471_ChIP-ChIP_T-47D_Human1.95626463
19FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90394003
20GATA1_26923725_Chip-Seq_HPCs_Mouse1.89766449
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.89533086
22ZNF274_21170338_ChIP-Seq_K562_Hela1.88806861
23SUZ12_27294783_Chip-Seq_NPCs_Mouse1.83015000
24VDR_22108803_ChIP-Seq_LS180_Human1.82497195
25NR3C1_21868756_ChIP-Seq_MCF10A_Human1.82407289
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.82152145
27ARNT_22903824_ChIP-Seq_MCF-7_Human1.78418487
28SMAD4_21799915_ChIP-Seq_A2780_Human1.76693944
29FOXM1_26456572_ChIP-Seq_MCF-7_Human1.75100964
30TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.71931395
31CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.70420161
32KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.69269191
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67389082
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.64527536
35RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.64174609
36ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.62655550
37KAP1_22055183_ChIP-Seq_ESCs_Mouse1.61725298
38ZNF217_24962896_ChIP-Seq_MCF-7_Human1.61324216
39STAT3_23295773_ChIP-Seq_U87_Human1.59181324
40TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.59114128
41FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.58585014
42WDR5_24793694_ChIP-Seq_LNCAP_Human1.57135502
43AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.56811478
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.55896891
45TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54564093
46STAT1_17558387_ChIP-Seq_HELA_Human1.54516905
47RNF2_27304074_Chip-Seq_NSC_Mouse1.53891664
48TP63_23658742_ChIP-Seq_EP156T_Human1.53319729
49AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.52725948
50AR_21572438_ChIP-Seq_LNCaP_Human1.51911010
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50956383
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.50314079
53TP53_18474530_ChIP-ChIP_U2OS_Human1.49611319
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46870387
55CBP_20019798_ChIP-Seq_JUKART_Human1.46870387
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.45640075
57POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44225023
58GBX2_23144817_ChIP-Seq_PC3_Human1.42728526
59TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.42662073
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.41863285
61PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40719530
62ETV1_20927104_ChIP-Seq_GIST48_Human1.40527802
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40292180
64PHF8_20622853_ChIP-Seq_HELA_Human1.40136035
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.39382669
66CRX_20693478_ChIP-Seq_RETINA_Mouse1.39328687
67GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39269704
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.38428341
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.37803936
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.37729575
71OCT4_18555785_Chip-Seq_ESCs_Mouse1.36992500
72FOXA1_25552417_ChIP-Seq_VCAP_Human1.36859108
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.36074012
74CTBP2_25329375_ChIP-Seq_LNCAP_Human1.35128347
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35099671
76KDM2B_26808549_Chip-Seq_REH_Human1.35065781
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.34317823
78MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32934068
79PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.32238549
80STAT1_20625510_ChIP-Seq_HELA_Human1.32153703
81HNFA_21074721_ChIP-Seq_CACO-2_Human1.31769619
82SMRT_27268052_Chip-Seq_Bcells_Human1.31077462
83TCF4_22108803_ChIP-Seq_LS180_Human1.30555528
84TBL1_22424771_ChIP-Seq_293T_Human1.29291622
85CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.29285460
86EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.28953139
87P300_18555785_Chip-Seq_ESCs_Mouse1.28326934
88P53_22387025_ChIP-Seq_ESCs_Mouse1.27821450
89ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.24800234
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.23515015
91GATA3_21867929_ChIP-Seq_CD8_Mouse1.23428282
92SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.23106806
93ESRRB_18555785_Chip-Seq_ESCs_Mouse1.22796159
94NFYA_21822215_ChIP-Seq_K562_Human1.22712857
95KLF4_18555785_Chip-Seq_ESCs_Mouse1.21866760
96STAT3_18555785_Chip-Seq_ESCs_Mouse1.21205096
97REST_21632747_ChIP-Seq_MESCs_Mouse1.20881211
98SOX2_22085726_ChIP-Seq_NPCs_Mouse1.20632323
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19890241
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19890241
101CMYC_18555785_Chip-Seq_ESCs_Mouse1.19806129
102OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19608576
103TP53_16413492_ChIP-PET_HCT116_Human1.19108080
104FUS_26573619_Chip-Seq_HEK293_Human1.17456471
105MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16981747
106SUZ12_18555785_Chip-Seq_ESCs_Mouse1.16293477
107RBPJ_21746931_ChIP-Seq_IB4_Human1.16171719
108RUNX2_22187159_ChIP-Seq_PCA_Human1.16016260
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15297205
110AR_25329375_ChIP-Seq_VCAP_Human1.14938716
111SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14376707
112RUNX1_27457419_Chip-Seq_LIVER_Mouse1.13938126
113SMAD3_21741376_ChIP-Seq_HESCs_Human1.13858546
114LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.13625782
115TDRD3_21172665_ChIP-Seq_MCF-7_Human1.13520181
116FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13507241
117CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13156231
118SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12017810
119CBX2_22325352_ChIP-Seq_293T-Rex_Human1.11633885
120P300_19829295_ChIP-Seq_ESCs_Human1.11576449
121TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10675407
122CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10648168
123ER_23166858_ChIP-Seq_MCF-7_Human1.10635493
124ZFX_18555785_Chip-Seq_ESCs_Mouse1.09698292
125PRDM14_20953172_ChIP-Seq_ESCs_Human1.09083274
126BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.09008297
127CDX2_22108803_ChIP-Seq_LS180_Human1.08463278
128GATA3_21867929_ChIP-Seq_TH1_Mouse1.08002292
129GF1_26923725_Chip-Seq_HPCs_Mouse1.07542272
130E2F1_18555785_Chip-Seq_ESCs_Mouse1.07527188
131CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07320682
132TAF15_26573619_Chip-Seq_HEK293_Human1.07105408
133CTCF_18555785_Chip-Seq_ESCs_Mouse1.06717302
134SOX2_18555785_Chip-Seq_ESCs_Mouse1.06333236
135PU1_27457419_Chip-Seq_LIVER_Mouse1.06087201
136CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05349173
137CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.05294761
138GATA6_21074721_ChIP-Seq_CACO-2_Human1.04682636
139RUNX1_27514584_Chip-Seq_MCF-7_Human1.03005294
140EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.02483246
141CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02240920
142PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01684918
143SMAD4_21741376_ChIP-Seq_HESCs_Human1.00888615
144IGF1R_20145208_ChIP-Seq_DFB_Human0.99111682
145BCAT_22108803_ChIP-Seq_LS180_Human0.98846203
146GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98166959
147RUNX1_26923725_Chip-Seq_HPCs_Mouse0.98006814
148KLF5_25053715_ChIP-Seq_YYC3_Human0.97715321
149RAD21_21589869_ChIP-Seq_MESCs_Mouse0.97456745
150CBP_21632823_ChIP-Seq_H3396_Human0.97160329
151FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.97086409
152AR_20517297_ChIP-Seq_VCAP_Human0.96753410
153FOXA2_19822575_ChIP-Seq_HepG2_Human0.96548413
154SMAD1_18555785_Chip-Seq_ESCs_Mouse0.96282948
155TCF4_23295773_ChIP-Seq_U87_Human0.96259039
156P53_21459846_ChIP-Seq_SAOS-2_Human0.95793057
157PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95737955
158ESR1_21235772_ChIP-Seq_MCF-7_Human0.95596083
159SALL1_21062744_ChIP-ChIP_HESCs_Human0.94951451
160GF1B_26923725_Chip-Seq_HPCs_Mouse0.94835944
161KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94209183
162SMC4_20622854_ChIP-Seq_HELA_Human0.93691529
163NMYC_18555785_Chip-Seq_ESCs_Mouse0.92970470
164MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.92837962
165SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.91677075
166RBPJ_22232070_ChIP-Seq_NCS_Mouse0.90274785
167FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89270075
168FOXA1_25329375_ChIP-Seq_VCAP_Human0.89270075
169SMAD4_21741376_ChIP-Seq_EPCs_Human0.88701756
170SPI1_26923725_Chip-Seq_HPCs_Mouse0.88498463
171NFYB_21822215_ChIP-Seq_K562_Human0.87666424
172ERG_20517297_ChIP-Seq_VCAP_Human0.86860376
173PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.86374942

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.80778958
2MP0008875_abnormal_xenobiotic_pharmacok5.33286877
3MP0001929_abnormal_gametogenesis5.33216253
4MP0008877_abnormal_DNA_methylation5.17068043
5MP0002653_abnormal_ependyma_morphology4.76576389
6MP0004043_abnormal_pH_regulation4.00153312
7MP0002210_abnormal_sex_determination3.77803874
8MP0005623_abnormal_meninges_morphology3.58554550
9MP0009780_abnormal_chondrocyte_physiolo3.55793960
10MP0002277_abnormal_respiratory_mucosa3.32139968
11MP0001145_abnormal_male_reproductive3.13236173
12MP0002161_abnormal_fertility/fecundity3.08056145
13MP0000653_abnormal_sex_gland2.76547478
14MP0000383_abnormal_hair_follicle2.43462651
15MP0002160_abnormal_reproductive_system2.36690789
16MP0002168_other_aberrant_phenotype2.01989407
17MP0010678_abnormal_skin_adnexa2.00353245
18MP0005410_abnormal_fertilization14.1702354
19MP0003195_calcinosis1.96338493
20MP0002282_abnormal_trachea_morphology1.87255951
21MP0002909_abnormal_adrenal_gland1.85432988
22MP0005670_abnormal_white_adipose1.85066061
23MP0009046_muscle_twitch1.77844024
24MP0000566_synostosis1.77274796
25MP0008057_abnormal_DNA_replication1.70545309
26MP0003656_abnormal_erythrocyte_physiolo1.70464574
27MP0002876_abnormal_thyroid_physiology1.69620490
28MP0002638_abnormal_pupillary_reflex1.59663428
29MP0002735_abnormal_chemical_nociception1.55131892
30MP0001984_abnormal_olfaction1.52952794
31MP0008058_abnormal_DNA_repair1.42569261
32MP0005395_other_phenotype1.36854506
33MP0001485_abnormal_pinna_reflex1.32319387
34MP0005220_abnormal_exocrine_pancreas1.27652351
35MP0002734_abnormal_mechanical_nocicepti1.26827121
36MP0005647_abnormal_sex_gland1.26286352
37MP0005389_reproductive_system_phenotype1.23595246
38MP0003011_delayed_dark_adaptation1.22156378
39MP0008995_early_reproductive_senescence1.21599976
40MP0003136_yellow_coat_color1.17078402
41MP0003646_muscle_fatigue1.15341045
42MP0005083_abnormal_biliary_tract1.13998733
43MP0000678_abnormal_parathyroid_gland1.11878854
44MP0002234_abnormal_pharynx_morphology1.11468058
45MP0002249_abnormal_larynx_morphology1.03256826
46MP0002102_abnormal_ear_morphology0.98549511
47MP0005248_abnormal_Harderian_gland0.97225021
48MP0001346_abnormal_lacrimal_gland0.94755901
49MP0001765_abnormal_ion_homeostasis0.93359621
50MP0000631_abnormal_neuroendocrine_gland0.93242589
51MP0001944_abnormal_pancreas_morphology0.93007055
52MP0010094_abnormal_chromosome_stability0.92260802
53MP0001270_distended_abdomen0.88348014
54MP0003786_premature_aging0.87470936
55MP0005551_abnormal_eye_electrophysiolog0.85546775
56MP0003950_abnormal_plasma_membrane0.84669049
57MP0001486_abnormal_startle_reflex0.84543012
58MP0000026_abnormal_inner_ear0.82904979
59MP0001970_abnormal_pain_threshold0.82812046
60MP0002837_dystrophic_cardiac_calcinosis0.81157140
61MP0009745_abnormal_behavioral_response0.79992093
62MP0004233_abnormal_muscle_weight0.79843623
63MP0008872_abnormal_physiological_respon0.79741327
64MP0004134_abnormal_chest_morphology0.78797672
65MP0005365_abnormal_bile_salt0.78149847
66MP0003890_abnormal_embryonic-extraembry0.76328320
67MP0001501_abnormal_sleep_pattern0.75151443
68MP0009643_abnormal_urine_homeostasis0.74606358
69MP0005645_abnormal_hypothalamus_physiol0.73813457
70MP0005085_abnormal_gallbladder_physiolo0.73284661
71MP0000681_abnormal_thyroid_gland0.72822311
72MP0005253_abnormal_eye_physiology0.72738282
73MP0002928_abnormal_bile_duct0.72198842
74MP0002136_abnormal_kidney_physiology0.68762571
75MP0010386_abnormal_urinary_bladder0.68528284
76MP0001727_abnormal_embryo_implantation0.68394405
77MP0003283_abnormal_digestive_organ0.68298140
78MP0003943_abnormal_hepatobiliary_system0.68159291
79MP0005377_hearing/vestibular/ear_phenot0.68043230
80MP0003878_abnormal_ear_physiology0.68043230
81MP0002132_abnormal_respiratory_system0.68032981
82MP0003252_abnormal_bile_duct0.67853609
83MP0008007_abnormal_cellular_replicative0.67793157
84MP0001502_abnormal_circadian_rhythm0.67609913
85MP0001293_anophthalmia0.67230677
86MP0004133_heterotaxia0.66601086
87MP0005310_abnormal_salivary_gland0.66436681
88MP0008961_abnormal_basal_metabolism0.64096522
89MP0002822_catalepsy0.63770126
90MP0003937_abnormal_limbs/digits/tail_de0.62049914
91MP0000955_abnormal_spinal_cord0.59242519
92MP0001664_abnormal_digestion0.59031782
93MP0005646_abnormal_pituitary_gland0.59010440
94MP0004085_abnormal_heartbeat0.57764333
95MP0005391_vision/eye_phenotype0.55866781
96MP0002233_abnormal_nose_morphology0.55206773
97MP0004885_abnormal_endolymph0.52644160
98MP0003953_abnormal_hormone_level0.52445186
99MP0009703_decreased_birth_body0.51548785
100MP0001756_abnormal_urination0.51073075
101MP0003115_abnormal_respiratory_system0.50415719
102MP0001119_abnormal_female_reproductive0.48166387
103MP0003861_abnormal_nervous_system0.46383631
104MP0001324_abnormal_eye_pigmentation0.45659574
105MP0003699_abnormal_female_reproductive0.43597744
106MP0006072_abnormal_retinal_apoptosis0.42471702
107MP0000432_abnormal_head_morphology0.41220686
108MP0000427_abnormal_hair_cycle0.40456975
109MP0002152_abnormal_brain_morphology0.39723093
110MP0001440_abnormal_grooming_behavior0.39307923
111MP0002133_abnormal_respiratory_system0.37138033
112MP0005388_respiratory_system_phenotype0.37138033
113MP0005397_hematopoietic_system_phenotyp0.35207848
114MP0001545_abnormal_hematopoietic_system0.35207848
115MP0004019_abnormal_vitamin_homeostasis0.35166432
116MP0009250_abnormal_appendicular_skeleto0.34454430
117MP0002971_abnormal_brown_adipose0.33611241
118MP0005195_abnormal_posterior_eye0.33570130
119MP0005636_abnormal_mineral_homeostasis0.32399204
120MP0003633_abnormal_nervous_system0.32190227
121MP0002092_abnormal_eye_morphology0.32063860
122MP0000647_abnormal_sebaceous_gland0.30471114
123MP0000358_abnormal_cell_content/0.29606155
124MP0001919_abnormal_reproductive_system0.29171168
125MP0009115_abnormal_fat_cell0.29114217
126MP0005394_taste/olfaction_phenotype0.27902338
127MP0005499_abnormal_olfactory_system0.27902338
128MP0003787_abnormal_imprinting0.27857832
129MP0000778_abnormal_nervous_system0.27530654
130MP0004808_abnormal_hematopoietic_stem0.26986605
131MP0002557_abnormal_social/conspecific_i0.26412597
132MP0004036_abnormal_muscle_relaxation0.26373522
133MP0002116_abnormal_craniofacial_bone0.26120905
134MP0002229_neurodegeneration0.25921003
135MP0001851_eye_inflammation0.25868636
136MP0003879_abnormal_hair_cell0.25089275
137MP0004145_abnormal_muscle_electrophysio0.25073131
138MP0003634_abnormal_glial_cell0.24668282
139MP0002109_abnormal_limb_morphology0.24644262
140MP0000462_abnormal_digestive_system0.24621093
141MP0005666_abnormal_adipose_tissue0.23761547
142MP0002752_abnormal_somatic_nervous0.23462283
143MP0001963_abnormal_hearing_physiology0.23303139
144MP0003942_abnormal_urinary_system0.23301481
145MP0004811_abnormal_neuron_physiology0.23284500
146MP0003111_abnormal_nucleus_morphology0.23194365
147MP0005379_endocrine/exocrine_gland_phen0.22939889
148MP0008789_abnormal_olfactory_epithelium0.22387761
149MP0002572_abnormal_emotion/affect_behav0.22285440
150MP0004270_analgesia0.21381408
151MP0005167_abnormal_blood-brain_barrier0.21095248
152MP0009697_abnormal_copulation0.21087581
153MP0002405_respiratory_system_inflammati0.20903959
154MP0003045_fibrosis0.20823224
155MP0000313_abnormal_cell_death0.19822861
156MP0010307_abnormal_tumor_latency0.19532697

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.67743578
2Abnormal respiratory epithelium morphology (HP:0012253)9.34011338
3Abnormal respiratory motile cilium morphology (HP:0005938)9.34011338
4Rhinitis (HP:0012384)8.92941981
5Chronic bronchitis (HP:0004469)7.14002648
6Nasal polyposis (HP:0100582)5.97137950
7Infertility (HP:0000789)5.36436876
8Bronchiectasis (HP:0002110)5.15880740
9Abnormality of the nasal mucosa (HP:0000433)4.93137260
10Nephronophthisis (HP:0000090)4.66015131
11Bronchitis (HP:0012387)4.36022768
12Recurrent sinusitis (HP:0011108)4.03632336
13Abnormality of the renal medulla (HP:0100957)3.63522855
14Recurrent otitis media (HP:0000403)3.28338245
15Male infertility (HP:0003251)3.13276484
16Medial flaring of the eyebrow (HP:0010747)3.03503030
17Chronic otitis media (HP:0000389)3.00339523
18Tubulointerstitial nephritis (HP:0001970)2.93076751
19Molar tooth sign on MRI (HP:0002419)2.81986219
20Abnormality of midbrain morphology (HP:0002418)2.81986219
21Abnormality of the lower motor neuron (HP:0002366)2.75898777
22Hyperactive renin-angiotensin system (HP:0000841)2.68391957
23Atelectasis (HP:0100750)2.62512134
24Pancreatic fibrosis (HP:0100732)2.62019171
25Recurrent bronchitis (HP:0002837)2.50702848
26Fibular hypoplasia (HP:0003038)2.50044941
27Postaxial foot polydactyly (HP:0001830)2.48886309
28Tubular atrophy (HP:0000092)2.46974279
29Tubulointerstitial abnormality (HP:0001969)2.42705126
30Congenital hepatic fibrosis (HP:0002612)2.41479332
31Abnormal spermatogenesis (HP:0008669)2.39443288
32Chronic sinusitis (HP:0011109)2.21618446
33Median cleft lip (HP:0000161)2.20255013
34Amyotrophic lateral sclerosis (HP:0007354)2.17621646
35Gonadotropin excess (HP:0000837)2.17070059
36Gait imbalance (HP:0002141)2.10649141
37Congenital primary aphakia (HP:0007707)2.10632302
38Stage 5 chronic kidney disease (HP:0003774)2.09557330
39True hermaphroditism (HP:0010459)2.07917755
40Abnormality of dentin (HP:0010299)2.03907970
41Facial cleft (HP:0002006)2.03734586
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.9675962
43Dynein arm defect of respiratory motile cilia (HP:0012255)11.8206389
44Absent/shortened dynein arms (HP:0200106)11.8206389
45Abnormal respiratory motile cilium physiology (HP:0012261)10.8314433
46Abnormality of the renal cortex (HP:0011035)1.97010011
47Tubulointerstitial fibrosis (HP:0005576)1.95810689
48Aplasia/Hypoplasia of the tongue (HP:0010295)1.95068867
49Microglossia (HP:0000171)1.92836892
50Abnormality of the dental root (HP:0006486)1.92613098
51Taurodontia (HP:0000679)1.92613098
52Abnormality of permanent molar morphology (HP:0011071)1.92613098
53Postaxial hand polydactyly (HP:0001162)1.89527864
54Furrowed tongue (HP:0000221)1.88475441
55Azoospermia (HP:0000027)1.88379761
56Short ribs (HP:0000773)1.87774099
57Supernumerary spleens (HP:0009799)1.86634978
58Decreased circulating renin level (HP:0003351)1.86633883
59Cystic liver disease (HP:0006706)1.85970040
60Nephrogenic diabetes insipidus (HP:0009806)1.83360062
61Abnormality of molar morphology (HP:0011070)1.81428547
62Abnormality of molar (HP:0011077)1.81428547
63Asplenia (HP:0001746)1.76853044
64Abnormality of the dental pulp (HP:0006479)1.74610614
65Aplasia/Hypoplasia of the spleen (HP:0010451)1.74140392
66Oculomotor apraxia (HP:0000657)1.73245281
67Absent frontal sinuses (HP:0002688)1.73218977
68Renal salt wasting (HP:0000127)1.69633887
69Polydipsia (HP:0001959)1.69281444
70Abnormal drinking behavior (HP:0030082)1.69281444
71Impulsivity (HP:0100710)1.65776940
72Hyperkalemia (HP:0002153)1.64740114
73Impaired proprioception (HP:0010831)1.63659127
74Renal dysplasia (HP:0000110)1.62164818
75Abnormal biliary tract physiology (HP:0012439)1.61857050
76Bile duct proliferation (HP:0001408)1.61857050
77Genital tract atresia (HP:0001827)1.60885221
78Pancreatic cysts (HP:0001737)1.59486217
79Aplasia/Hypoplasia of the fibula (HP:0006492)1.59316185
80Poor coordination (HP:0002370)1.58938189
81Hyperaldosteronism (HP:0000859)1.56986898
82Hypoplasia of the capital femoral epiphysis (HP:0003090)1.56346261
83Aplasia/Hypoplasia of the lens (HP:0008063)1.53551335
84Absent rod-and cone-mediated responses on ERG (HP:0007688)1.52107270
85Abnormality of renin-angiotensin system (HP:0000847)1.51835355
86Vaginal atresia (HP:0000148)1.51078226
8711 pairs of ribs (HP:0000878)1.49986622
88Occipital encephalocele (HP:0002085)1.49201045
89Abnormality of chloride homeostasis (HP:0011422)1.48770146
90Short thorax (HP:0010306)1.47783314
91Chronic hepatic failure (HP:0100626)1.47438882
92Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.47389645
93J-shaped sella turcica (HP:0002680)1.44398883
94Abnormality of macular pigmentation (HP:0008002)1.41967885
95Abnormality of renal excretion (HP:0011036)1.41709096
96Upper motor neuron abnormality (HP:0002127)1.41550064
97Hypokalemic alkalosis (HP:0001949)1.36936487
98Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.34661764
99Absent epiphyses (HP:0010577)1.34661764
100Cone-rod dystrophy (HP:0000548)1.33158099
101Bell-shaped thorax (HP:0001591)1.31850563
102Abnormal rod and cone electroretinograms (HP:0008323)1.31520939
103Nephropathy (HP:0000112)1.30719253
104Decreased central vision (HP:0007663)1.28649105
105Degeneration of anterior horn cells (HP:0002398)1.27665429
106Abnormality of the anterior horn cell (HP:0006802)1.27665429
107Short nail (HP:0001799)1.27402838
108Nephroblastoma (Wilms tumor) (HP:0002667)1.27166604
109Preaxial hand polydactyly (HP:0001177)1.26652145
110Abnormality of ocular smooth pursuit (HP:0000617)1.26267567
111Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.22381517
112Absent speech (HP:0001344)1.20785209
113Anencephaly (HP:0002323)1.19423551
114Polycystic kidney dysplasia (HP:0000113)1.18912736
115Retinitis pigmentosa (HP:0000510)1.18091764
116Male pseudohermaphroditism (HP:0000037)1.16595493
117Embryonal renal neoplasm (HP:0011794)1.16398343
118Polyuria (HP:0000103)1.15475980
119Sclerocornea (HP:0000647)1.12786670
120Abnormal urine output (HP:0012590)1.12618695
121Abnormality of the frontal sinuses (HP:0002687)1.11645484
122Central scotoma (HP:0000603)1.10282287
123Fetal akinesia sequence (HP:0001989)1.09741823
124Prominent nasal bridge (HP:0000426)1.08682405
125Lip pit (HP:0100267)1.07342318
126Narrow forehead (HP:0000341)1.06183159
127Bifid scrotum (HP:0000048)1.04366576
128Glucose intolerance (HP:0000833)1.02213844
129Highly arched eyebrow (HP:0002553)1.01206203

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.93878475
2PDK48.93878475
3PDK25.82091846
4MST45.26750734
5TESK13.95635045
6FRK3.68014598
7PRKD33.27721868
8EPHA23.04858865
9PNCK2.97751537
10PTK2B2.67478052
11ICK2.61770614
12WNK42.60635868
13STK392.58853287
14MAPK152.33044361
15MAPKAPK32.19797285
16NME12.03894054
17MAP3K21.95886829
18LATS11.73280202
19STK241.58798639
20NEK21.56881359
21BCR1.56530305
22ACVR1B1.49010970
23MAP3K71.45861683
24INSRR1.43826257
25STK381.26307303
26TLK11.25363488
27WNK11.04998379
28TRPM71.02830682
29NLK0.98593839
30LMTK20.97692607
31WEE10.95138102
32IRAK10.94492010
33ERBB30.88508390
34STK30.87911474
35ADRBK20.87586171
36MAP4K20.85702291
37PDK10.85062007
38STK100.83166585
39GRK10.82482716
40CSK0.82134442
41TYRO30.81807479
42PRKAA20.80813624
43EPHA30.80145165
44DYRK30.78023034
45TTK0.77719485
46FER0.74898552
47PASK0.74348481
48MST1R0.73902786
49PRKCI0.73529368
50CCNB10.72432454
51CDC70.69562951
52PLK40.67228548
53PINK10.65290192
54DYRK1B0.65179396
55MAP3K30.61952590
56NTRK30.61906509
57MAP2K70.59653544
58MAPK130.59141300
59STK38L0.59010621
60ERBB20.58332317
61SGK10.58070292
62SGK20.57148034
63MUSK0.56790277
64NTRK20.55819330
65CASK0.55289777
66CHEK20.53893280
67CAMK1G0.53677007
68ADRBK10.50864829
69FGFR20.50277924
70EPHB10.48446105
71ATR0.47050477
72CHEK10.46180473
73HIPK20.43742285
74SGK2230.43537938
75SGK4940.43537938
76PRKCE0.42931506
77LRRK20.41085482
78MAP3K90.40837943
79PAK20.40033949
80BRSK20.39197028
81PRKCG0.38727695
82ATM0.36909453
83MET0.35508465
84CDK30.34638441
85MAP3K120.34398714
86MAP3K40.33152191
87ROCK10.33082082
88PLK10.32431097
89NEK60.31609481
90PAK30.31546131
91RIPK40.31279005
92MARK30.30668223
93PDPK10.29838075
94FGFR30.29640835
95ABL10.29221836
96TNK20.29077109
97CDK120.28055223
98DYRK1A0.26974848
99TBK10.26534695
100IRAK20.26231449
101CDC42BPA0.24800499
102MKNK20.23592252
103BRAF0.23520662
104EPHA40.23506449
105SRPK10.23220640
106PRKCD0.22889858
107CAMKK10.22730597
108PAK10.22400921
109MAP2K20.21636197
110NEK90.21466696
111MELK0.21079220
112PRKAA10.20919790
113MAP2K40.19804233
114MTOR0.19679942
115PRKG20.18507359
116OBSCN0.17815205
117MAP2K60.17475118
118BMPR1B0.17309728
119CAMK2G0.16889339
120RPS6KB10.15707415
121PRKG10.14418376
122WNK30.14267522
123AKT30.13707197
124EEF2K0.13315221
125MARK10.11350899
126PRKACG0.09551810
127PRKDC0.08946434
128AURKA0.08538091
129GSK3B0.08449717
130PRKCQ0.08319443
131MAPK100.08004341
132MAPKAPK50.07825412
133MARK20.07740108
134PRKCZ0.07667958
135PDGFRB0.07514708
136CSNK2A10.07462010
137BRSK10.07416948
138CDK10.07204519
139MAPK80.06368696
140CSNK1D0.06176685
141GSK3A0.05857267
142CAMK2A0.05505039
143CDK20.02904440
144STK110.02832930
145CSNK2A20.02779055
146PRKCB0.02667622
147PRKACA0.02259111
148TESK20.00415751
149PRKACB0.00323756
150CDK15-0.0287376
151RPS6KA1-0.0284867
152EGFR-0.0236790
153MAPK14-0.0224897
154RPS6KA3-0.0222999
155MAPK1-0.0194463
156OXSR1-0.0139722
157PRKCA-0.0106867
158CSNK1E-0.0103991
159STK16-0.0062438

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.75785739
2Histidine metabolism_Homo sapiens_hsa003403.90366594
3Phenylalanine metabolism_Homo sapiens_hsa003603.88849980
4Pyruvate metabolism_Homo sapiens_hsa006203.88588962
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.47873945
6Propanoate metabolism_Homo sapiens_hsa006403.46805151
7Basal transcription factors_Homo sapiens_hsa030223.13579442
8beta-Alanine metabolism_Homo sapiens_hsa004103.00449821
9Fatty acid biosynthesis_Homo sapiens_hsa000612.91642984
10Tyrosine metabolism_Homo sapiens_hsa003502.87203740
11Fanconi anemia pathway_Homo sapiens_hsa034602.84002359
12Glucagon signaling pathway_Homo sapiens_hsa049222.69900629
13Pentose phosphate pathway_Homo sapiens_hsa000302.67806827
14Huntingtons disease_Homo sapiens_hsa050162.53754075
15Dorso-ventral axis formation_Homo sapiens_hsa043202.47460344
16Caffeine metabolism_Homo sapiens_hsa002322.46880565
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.17685389
18Linoleic acid metabolism_Homo sapiens_hsa005912.08402924
19Selenocompound metabolism_Homo sapiens_hsa004502.02024195
20Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.97891233
21Oocyte meiosis_Homo sapiens_hsa041141.93384180
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.82327957
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.81530530
24Amphetamine addiction_Homo sapiens_hsa050311.74099059
25Glycerolipid metabolism_Homo sapiens_hsa005611.72755116
26Circadian rhythm_Homo sapiens_hsa047101.62703913
27PPAR signaling pathway_Homo sapiens_hsa033201.57166018
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.56643092
29Butanoate metabolism_Homo sapiens_hsa006501.53396445
30Steroid hormone biosynthesis_Homo sapiens_hsa001401.50985365
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.45937047
32Renin secretion_Homo sapiens_hsa049241.45688727
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.44597995
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.42508634
35Peroxisome_Homo sapiens_hsa041461.39375113
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.37932275
37Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.37865007
38Carbohydrate digestion and absorption_Homo sapiens_hsa049731.31978937
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.31099310
40mRNA surveillance pathway_Homo sapiens_hsa030151.30913177
41Glycerophospholipid metabolism_Homo sapiens_hsa005641.26068570
42Purine metabolism_Homo sapiens_hsa002301.24526782
43Phototransduction_Homo sapiens_hsa047441.23700179
44Tight junction_Homo sapiens_hsa045301.23453778
45Ether lipid metabolism_Homo sapiens_hsa005651.22055322
46Cardiac muscle contraction_Homo sapiens_hsa042601.18015968
47Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.12343186
48Fructose and mannose metabolism_Homo sapiens_hsa000511.09846317
49Nicotine addiction_Homo sapiens_hsa050331.09077051
50Carbon metabolism_Homo sapiens_hsa012001.08730871
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08717880
52RNA transport_Homo sapiens_hsa030131.08238236
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05391031
54Primary bile acid biosynthesis_Homo sapiens_hsa001201.04034556
55Tryptophan metabolism_Homo sapiens_hsa003800.99246386
56Mineral absorption_Homo sapiens_hsa049780.98880575
57Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.93374975
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.92137477
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90371354
60ABC transporters_Homo sapiens_hsa020100.90366846
61Long-term potentiation_Homo sapiens_hsa047200.88880281
62Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85570609
63Taste transduction_Homo sapiens_hsa047420.85308054
64Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85030103
65Starch and sucrose metabolism_Homo sapiens_hsa005000.82744361
66Calcium signaling pathway_Homo sapiens_hsa040200.82127199
67Olfactory transduction_Homo sapiens_hsa047400.81997921
68Renin-angiotensin system_Homo sapiens_hsa046140.81088591
69Regulation of autophagy_Homo sapiens_hsa041400.79497879
70Antigen processing and presentation_Homo sapiens_hsa046120.78764260
71Biosynthesis of amino acids_Homo sapiens_hsa012300.76849235
72Serotonergic synapse_Homo sapiens_hsa047260.75770769
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.73025581
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72156302
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72085656
76Homologous recombination_Homo sapiens_hsa034400.72027600
77Estrogen signaling pathway_Homo sapiens_hsa049150.71756056
78cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71154594
79Glutathione metabolism_Homo sapiens_hsa004800.70969650
80Nitrogen metabolism_Homo sapiens_hsa009100.70502670
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68072410
82Insulin secretion_Homo sapiens_hsa049110.65659842
83Arachidonic acid metabolism_Homo sapiens_hsa005900.62607220
84Fatty acid metabolism_Homo sapiens_hsa012120.62405314
85Choline metabolism in cancer_Homo sapiens_hsa052310.62133822
86Circadian entrainment_Homo sapiens_hsa047130.61850728
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60656982
88Fat digestion and absorption_Homo sapiens_hsa049750.60240145
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59542717
90Collecting duct acid secretion_Homo sapiens_hsa049660.59416942
91Chemical carcinogenesis_Homo sapiens_hsa052040.54594465
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53997687
93RNA degradation_Homo sapiens_hsa030180.53012327
94Fatty acid degradation_Homo sapiens_hsa000710.52986420
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52234065
96Thyroid hormone synthesis_Homo sapiens_hsa049180.51231084
97Hedgehog signaling pathway_Homo sapiens_hsa043400.50400202
98Ovarian steroidogenesis_Homo sapiens_hsa049130.48454304
99Glutamatergic synapse_Homo sapiens_hsa047240.47237063
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46877192
101Sphingolipid metabolism_Homo sapiens_hsa006000.46253947
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46099105
103Protein digestion and absorption_Homo sapiens_hsa049740.45337457
104Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45054459
105Drug metabolism - other enzymes_Homo sapiens_hsa009830.44484954
106N-Glycan biosynthesis_Homo sapiens_hsa005100.42339520
107Bile secretion_Homo sapiens_hsa049760.42053351
108Metabolic pathways_Homo sapiens_hsa011000.41248528
109Synaptic vesicle cycle_Homo sapiens_hsa047210.40739353
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.39960753
111Gastric acid secretion_Homo sapiens_hsa049710.39774154
112Inositol phosphate metabolism_Homo sapiens_hsa005620.37577980
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36773101
114Wnt signaling pathway_Homo sapiens_hsa043100.36364910
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.36180568
116Salivary secretion_Homo sapiens_hsa049700.36082762
117Type II diabetes mellitus_Homo sapiens_hsa049300.35149628
118cAMP signaling pathway_Homo sapiens_hsa040240.34658148
119Vitamin digestion and absorption_Homo sapiens_hsa049770.33930680
120Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33488143
121Complement and coagulation cascades_Homo sapiens_hsa046100.33442701
122Pyrimidine metabolism_Homo sapiens_hsa002400.33422870
123Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32441141
124Vascular smooth muscle contraction_Homo sapiens_hsa042700.30082607
125Endocytosis_Homo sapiens_hsa041440.29931494
126Adherens junction_Homo sapiens_hsa045200.29153300
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27601350
128Notch signaling pathway_Homo sapiens_hsa043300.26104990
129Hepatitis C_Homo sapiens_hsa051600.25969509
130Pancreatic secretion_Homo sapiens_hsa049720.25828845
131B cell receptor signaling pathway_Homo sapiens_hsa046620.25633065
132VEGF signaling pathway_Homo sapiens_hsa043700.25611221
133Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.25306669
134AMPK signaling pathway_Homo sapiens_hsa041520.25060120
135Dopaminergic synapse_Homo sapiens_hsa047280.24709525
136Insulin resistance_Homo sapiens_hsa049310.24449589
137Systemic lupus erythematosus_Homo sapiens_hsa053220.24203723
138Arginine and proline metabolism_Homo sapiens_hsa003300.23635336
139Morphine addiction_Homo sapiens_hsa050320.23380164
140Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23245064
141Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.21493106
142SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21402484
143Aldosterone synthesis and secretion_Homo sapiens_hsa049250.21372238
144Type I diabetes mellitus_Homo sapiens_hsa049400.21310965
145Cocaine addiction_Homo sapiens_hsa050300.21212244
146Retinol metabolism_Homo sapiens_hsa008300.20860602
147Basal cell carcinoma_Homo sapiens_hsa052170.19154086
148Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.18646610
149GABAergic synapse_Homo sapiens_hsa047270.17705457
150Jak-STAT signaling pathway_Homo sapiens_hsa046300.17397689
151Oxytocin signaling pathway_Homo sapiens_hsa049210.15824969

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