CFAP74

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.06002341
2cilium movement (GO:0003341)7.71982971
3motile cilium assembly (GO:0044458)7.57324288
4epithelial cilium movement (GO:0003351)7.35995594
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.25440044
6piRNA metabolic process (GO:0034587)7.11374367
7acrosome reaction (GO:0007340)6.09980826
8sperm motility (GO:0030317)5.92810982
9fusion of sperm to egg plasma membrane (GO:0007342)5.81383851
10regulation of cilium movement (GO:0003352)5.78141267
11multicellular organism reproduction (GO:0032504)5.40056361
12male meiosis (GO:0007140)5.21936790
13axoneme assembly (GO:0035082)5.17494099
14DNA methylation involved in gamete generation (GO:0043046)5.02915820
15spermatid development (GO:0007286)4.92157096
16L-fucose catabolic process (GO:0042355)4.84306462
17fucose catabolic process (GO:0019317)4.84306462
18L-fucose metabolic process (GO:0042354)4.84306462
19sperm-egg recognition (GO:0035036)4.84231132
20protein localization to cilium (GO:0061512)4.79114094
21ventricular system development (GO:0021591)4.76150354
22acrosome assembly (GO:0001675)4.70479937
23plasma membrane fusion (GO:0045026)4.66577062
24behavioral response to nicotine (GO:0035095)4.57490658
25cell-cell recognition (GO:0009988)4.40746970
26intraciliary transport (GO:0042073)4.35921860
27binding of sperm to zona pellucida (GO:0007339)4.27115782
28synaptonemal complex organization (GO:0070193)4.10482075
29male meiosis I (GO:0007141)4.08439500
30reproduction (GO:0000003)3.98271385
31calcium ion-dependent exocytosis (GO:0017156)3.87534119
32cilium organization (GO:0044782)3.86305903
33single fertilization (GO:0007338)3.84697768
34cilium assembly (GO:0042384)3.81829949
35synaptonemal complex assembly (GO:0007130)3.74659115
36DNA deamination (GO:0045006)3.69030862
37microtubule depolymerization (GO:0007019)3.62985639
38negative regulation of inclusion body assembly (GO:0090084)3.62949292
39cellular ketone body metabolic process (GO:0046950)3.48266378
40meiotic cell cycle (GO:0051321)3.43294295
41indolalkylamine metabolic process (GO:0006586)3.33202018
42kynurenine metabolic process (GO:0070189)3.32613316
43tryptophan catabolic process (GO:0006569)3.32440160
44indole-containing compound catabolic process (GO:0042436)3.32440160
45indolalkylamine catabolic process (GO:0046218)3.32440160
46centriole assembly (GO:0098534)3.29688070
47negative regulation of T cell differentiation in thymus (GO:0033085)3.27660915
48cilium morphogenesis (GO:0060271)3.27381153
49chromosome organization involved in meiosis (GO:0070192)3.26341207
50left/right axis specification (GO:0070986)3.25684249
51cornea development in camera-type eye (GO:0061303)3.25314164
52fertilization (GO:0009566)3.22191499
53protein polyglutamylation (GO:0018095)3.22163972
54detection of light stimulus involved in sensory perception (GO:0050962)3.21401845
55detection of light stimulus involved in visual perception (GO:0050908)3.21401845
56cell wall macromolecule catabolic process (GO:0016998)3.20164660
57cell wall macromolecule metabolic process (GO:0044036)3.20164660
58sperm capacitation (GO:0048240)3.18462641
59spermatogenesis (GO:0007283)3.15021754
60ketone body metabolic process (GO:1902224)3.14041559
61male gamete generation (GO:0048232)3.13857697
62meiotic nuclear division (GO:0007126)3.13161265
63exogenous drug catabolic process (GO:0042738)3.11912501
64left/right pattern formation (GO:0060972)3.10463774
65cellular component assembly involved in morphogenesis (GO:0010927)3.10396209
66photoreceptor cell maintenance (GO:0045494)3.08841101
67regulation of microtubule-based movement (GO:0060632)3.02955187
68meiosis I (GO:0007127)3.02554921
69microtubule-based movement (GO:0007018)3.02083438
70G-protein coupled receptor internalization (GO:0002031)3.00832248
71retinal cone cell development (GO:0046549)2.99338297
72detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.99297022
73germ cell development (GO:0007281)2.98365433
74platelet dense granule organization (GO:0060155)2.97987878
75gamete generation (GO:0007276)2.94990272
76ionotropic glutamate receptor signaling pathway (GO:0035235)2.94560499
77synapsis (GO:0007129)2.93936637
78startle response (GO:0001964)2.92358556
79drug catabolic process (GO:0042737)2.91708988
80adaptation of signaling pathway (GO:0023058)2.89620764
81negative regulation of synaptic transmission, GABAergic (GO:0032229)2.88007769
82tryptophan metabolic process (GO:0006568)2.87553771
83response to xenobiotic stimulus (GO:0009410)2.87023603
84microtubule severing (GO:0051013)2.84918908
85polyketide metabolic process (GO:0030638)2.81554418
86doxorubicin metabolic process (GO:0044598)2.81554418
87daunorubicin metabolic process (GO:0044597)2.81554418
88neural tube formation (GO:0001841)2.80431684
89negative regulation of telomere maintenance (GO:0032205)2.79822228
90cellular process involved in reproduction in multicellular organism (GO:0022412)2.78538127
91water-soluble vitamin biosynthetic process (GO:0042364)2.75022867
92respiratory chain complex IV assembly (GO:0008535)2.74201027
93regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.74149986
94regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.74036538
95organic cation transport (GO:0015695)2.73827280
96regulation of translation, ncRNA-mediated (GO:0045974)2.73517250
97negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.73517250
98negative regulation of translation, ncRNA-mediated (GO:0040033)2.73517250
99synaptic transmission, glutamatergic (GO:0035249)2.73304778
100centriole replication (GO:0007099)2.72550695
101regulation of meiosis I (GO:0060631)2.72043925
102regulation of short-term neuronal synaptic plasticity (GO:0048172)2.71859497
103positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.71737233
104regulation of inclusion body assembly (GO:0090083)2.70757050
105gamma-aminobutyric acid transport (GO:0015812)2.65791433
106membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.64438158
107phosphorelay signal transduction system (GO:0000160)2.63922393
108membrane depolarization during action potential (GO:0086010)2.63836610
109negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.62626122
110rRNA catabolic process (GO:0016075)2.62371428
111cellular biogenic amine catabolic process (GO:0042402)2.59654619
112amine catabolic process (GO:0009310)2.59654619
113reflex (GO:0060004)2.59586431
114vitamin transmembrane transport (GO:0035461)2.59554980
115preassembly of GPI anchor in ER membrane (GO:0016254)2.59041238
116protein complex biogenesis (GO:0070271)2.58210133
117indole-containing compound metabolic process (GO:0042430)2.57170937
118negative regulation of mast cell activation (GO:0033004)2.56663310
119fucosylation (GO:0036065)2.55536666
120synaptic vesicle docking involved in exocytosis (GO:0016081)2.55248262
121neuronal action potential (GO:0019228)2.54785857
122mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.53760570
123mitochondrial respiratory chain complex I assembly (GO:0032981)2.53760570
124NADH dehydrogenase complex assembly (GO:0010257)2.53760570
125calcium ion import (GO:0070509)2.51503728
126response to auditory stimulus (GO:0010996)2.51402884
127glutamate receptor signaling pathway (GO:0007215)2.51254394
128benzene-containing compound metabolic process (GO:0042537)2.50085252
129regulation of action potential (GO:0098900)2.49297235
130behavioral response to ethanol (GO:0048149)2.47258147
131cell recognition (GO:0008037)2.47124738
132nucleoside diphosphate catabolic process (GO:0009134)2.47088181
133primary amino compound metabolic process (GO:1901160)2.46847568
134response to pheromone (GO:0019236)2.46577916
135protein-cofactor linkage (GO:0018065)2.45617039
136urinary tract smooth muscle contraction (GO:0014848)2.45068821
137regulation of glutamate receptor signaling pathway (GO:1900449)2.44761944
138cell projection assembly (GO:0030031)2.44757183
139regulation of rhodopsin mediated signaling pathway (GO:0022400)2.44138847
140cellular response to ATP (GO:0071318)2.43862117
141photoreceptor cell development (GO:0042461)2.43810895
142nucleoside diphosphate phosphorylation (GO:0006165)2.43162657
143microtubule bundle formation (GO:0001578)2.43015471
144rhodopsin mediated signaling pathway (GO:0016056)2.41880145
145G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.41644907
146one-carbon compound transport (GO:0019755)2.41341403
147cytochrome complex assembly (GO:0017004)2.40746636
148determination of left/right symmetry (GO:0007368)2.40120524
149spinal cord motor neuron differentiation (GO:0021522)2.40027955
150regulation of chromatin binding (GO:0035561)2.39620307
151nonmotile primary cilium assembly (GO:0035058)2.38916766
152positive regulation of protein sumoylation (GO:0033235)2.37163861
153ubiquinone biosynthetic process (GO:0006744)2.36284474
154neuron-neuron synaptic transmission (GO:0007270)2.35743902
155regulation of collateral sprouting (GO:0048670)2.35376778
156positive regulation of fatty acid transport (GO:2000193)2.34737460
157neurotransmitter metabolic process (GO:0042133)2.34088423
158sulfation (GO:0051923)2.33526156
159smoothened signaling pathway (GO:0007224)2.32300615
160GPI anchor metabolic process (GO:0006505)2.32208355
161mitochondrial respiratory chain complex assembly (GO:0033108)2.31619559
162regulation of mesoderm development (GO:2000380)2.31037241
163vocalization behavior (GO:0071625)2.30164850
164cerebellar Purkinje cell differentiation (GO:0021702)2.29913705
165microglial cell activation (GO:0001774)2.28932261
166multicellular organismal reproductive process (GO:0048609)2.28537883
167cilium or flagellum-dependent cell motility (GO:0001539)11.7342089

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.65825777
2GBX2_23144817_ChIP-Seq_PC3_Human3.53016239
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.47504237
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.14294395
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.11372162
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.36084633
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.30030457
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.22799095
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.15831477
10REST_21632747_ChIP-Seq_MESCs_Mouse1.99797531
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.94221387
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94167102
13SUZ12_27294783_Chip-Seq_NPCs_Mouse1.91859676
14SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.88686908
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.88396510
16NFE2_27457419_Chip-Seq_LIVER_Mouse1.86301637
17PCGF2_27294783_Chip-Seq_NPCs_Mouse1.76738941
18DROSHA_22980978_ChIP-Seq_HELA_Human1.73507940
19EWS_26573619_Chip-Seq_HEK293_Human1.71912212
20TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.71343385
21POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.70683138
22TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.70683138
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.63818251
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.63684968
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.59630128
26NANOG_18555785_Chip-Seq_ESCs_Mouse1.59432454
27SMAD4_21799915_ChIP-Seq_A2780_Human1.58906249
28RNF2_27304074_Chip-Seq_NSC_Mouse1.58515364
29EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.56901592
30VDR_22108803_ChIP-Seq_LS180_Human1.56792900
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.55384181
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.55359656
33CBP_20019798_ChIP-Seq_JUKART_Human1.55359656
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55334242
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.54436417
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.52887820
37STAT3_18555785_Chip-Seq_ESCs_Mouse1.51463535
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50116593
39E2F1_18555785_Chip-Seq_ESCs_Mouse1.49231487
40NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48795409
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.48700481
42P53_22387025_ChIP-Seq_ESCs_Mouse1.48277647
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.45389613
44TAF15_26573619_Chip-Seq_HEK293_Human1.44654768
45SUZ12_18555785_Chip-Seq_ESCs_Mouse1.44489206
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42389097
47TP53_22573176_ChIP-Seq_HFKS_Human1.41538501
48P300_19829295_ChIP-Seq_ESCs_Human1.41262590
49UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40294984
50SALL1_21062744_ChIP-ChIP_HESCs_Human1.40144080
51EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.39253258
52RUNX1_27457419_Chip-Seq_LIVER_Mouse1.38901780
53TCF4_23295773_ChIP-Seq_U87_Human1.38198894
54P300_18555785_Chip-Seq_ESCs_Mouse1.38018545
55FOXA1_27270436_Chip-Seq_PROSTATE_Human1.37004379
56FOXA1_25329375_ChIP-Seq_VCAP_Human1.37004379
57SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.36230093
58NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.36099174
59TCF4_22108803_ChIP-Seq_LS180_Human1.35924579
60CMYC_18555785_Chip-Seq_ESCs_Mouse1.35823873
61OCT4_18555785_Chip-Seq_ESCs_Mouse1.35613586
62PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35531831
63GATA3_21878914_ChIP-Seq_MCF-7_Human1.32469624
64NANOG_19829295_ChIP-Seq_ESCs_Human1.31882861
65SOX2_19829295_ChIP-Seq_ESCs_Human1.31882861
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31758360
67IRF1_19129219_ChIP-ChIP_H3396_Human1.31666146
68NMYC_18555785_Chip-Seq_ESCs_Mouse1.31321455
69ETV2_25802403_ChIP-Seq_MESCs_Mouse1.30834413
70TAL1_26923725_Chip-Seq_HPCs_Mouse1.30254630
71SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.29798728
72NCOR_22424771_ChIP-Seq_293T_Human1.29189279
73STAT3_23295773_ChIP-Seq_U87_Human1.28334199
74SOX2_18555785_Chip-Seq_ESCs_Mouse1.28304571
75ESRRB_18555785_Chip-Seq_ESCs_Mouse1.27023083
76JARID2_20064375_ChIP-Seq_MESCs_Mouse1.26839911
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.26428729
78SMAD4_21741376_ChIP-Seq_EPCs_Human1.26348597
79KLF4_18555785_Chip-Seq_ESCs_Mouse1.26198058
80EZH2_27294783_Chip-Seq_ESCs_Mouse1.25891674
81PU1_27457419_Chip-Seq_LIVER_Mouse1.25097236
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24114572
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23963958
84ZFX_18555785_Chip-Seq_ESCs_Mouse1.23039694
85AR_20517297_ChIP-Seq_VCAP_Human1.22677193
86IKZF1_21737484_ChIP-ChIP_HCT116_Human1.22660076
87KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22637914
88AR_21572438_ChIP-Seq_LNCaP_Human1.22222706
89ELK4_26923725_Chip-Seq_MESODERM_Mouse1.21490116
90RNF2_27304074_Chip-Seq_ESCs_Mouse1.21054103
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20809535
92SMAD3_21741376_ChIP-Seq_EPCs_Human1.20784694
93EZH2_27304074_Chip-Seq_ESCs_Mouse1.18246432
94CTCF_18555785_Chip-Seq_ESCs_Mouse1.17527100
95EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.17505554
96SUZ12_27294783_Chip-Seq_ESCs_Mouse1.17062747
97HOXB7_26014856_ChIP-Seq_BT474_Human1.16266592
98OCT4_21477851_ChIP-Seq_ESCs_Mouse1.15319471
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15108353
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14914014
101HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.14521577
102FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14115852
103CRX_20693478_ChIP-Seq_RETINA_Mouse1.13540250
104PRDM14_20953172_ChIP-Seq_ESCs_Human1.13421624
105RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12912565
106TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12521786
107CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.12316629
108NOTCH1_21737748_ChIP-Seq_TLL_Human1.12201094
109KDM2B_26808549_Chip-Seq_REH_Human1.12037365
110ZNF274_21170338_ChIP-Seq_K562_Hela1.11251923
111TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11213763
112SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11178650
113LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10957998
114ETV1_20927104_ChIP-Seq_GIST48_Human1.09806392
115REST_18959480_ChIP-ChIP_MESCs_Mouse1.09634837
116FUS_26573619_Chip-Seq_HEK293_Human1.09577873
117MTF2_20144788_ChIP-Seq_MESCs_Mouse1.08842660
118FLI1_21867929_ChIP-Seq_TH2_Mouse1.08467917
119MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08347883
120MYC_19829295_ChIP-Seq_ESCs_Human1.07707821
121MYC_18940864_ChIP-ChIP_HL60_Human1.07094870
122IGF1R_20145208_ChIP-Seq_DFB_Human1.06966621
123SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06451214
124ERA_21632823_ChIP-Seq_H3396_Human1.06427877
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05903375
126ER_23166858_ChIP-Seq_MCF-7_Human1.05650280
127BCAT_22108803_ChIP-Seq_LS180_Human1.05568129
128AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04184542
129TAF2_19829295_ChIP-Seq_ESCs_Human1.04114400
130SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.04108711
131FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03830711
132PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.03463250
133SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.03328383
134RUNX2_22187159_ChIP-Seq_PCA_Human1.03252913
135STAT1_17558387_ChIP-Seq_HELA_Human1.03189906
136AR_25329375_ChIP-Seq_VCAP_Human1.03159478
137P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02559529
138E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02096293
139PHF8_20622853_ChIP-Seq_HELA_Human1.01652239
140CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01559459
141RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01144623
142SMAD_19615063_ChIP-ChIP_OVARY_Human0.99528701
143CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.99437728
144EGR1_23403033_ChIP-Seq_LIVER_Mouse0.99275588
145TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98134324
146AUTS2_25519132_ChIP-Seq_293T-REX_Human0.97827823
147TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.97096827
148GATA1_26923725_Chip-Seq_HPCs_Mouse0.96640934
149TDRD3_21172665_ChIP-Seq_MCF-7_Human0.96355551
150FOXH1_21741376_ChIP-Seq_EPCs_Human0.95431842
151RBPJ_21746931_ChIP-Seq_IB4_Human0.95025167

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.57457858
2MP0008875_abnormal_xenobiotic_pharmacok3.49331037
3MP0008877_abnormal_DNA_methylation3.04155713
4MP0003195_calcinosis2.96800550
5MP0001984_abnormal_olfaction2.83971373
6MP0009046_muscle_twitch2.77336426
7MP0006292_abnormal_olfactory_placode2.77302992
8MP0003698_abnormal_male_reproductive2.70160081
9MP0004859_abnormal_synaptic_plasticity2.61340295
10MP0001188_hyperpigmentation2.51993765
11MP0005645_abnormal_hypothalamus_physiol2.49025074
12MP0001929_abnormal_gametogenesis2.41559640
13MP0002653_abnormal_ependyma_morphology2.37775558
14MP0005646_abnormal_pituitary_gland2.36121834
15MP0004043_abnormal_pH_regulation2.34442470
16MP0005409_darkened_coat_color2.32600268
17MP0003880_abnormal_central_pattern2.19190778
18MP0001986_abnormal_taste_sensitivity2.18450525
19MP0003136_yellow_coat_color2.16615916
20MP0000015_abnormal_ear_pigmentation2.09681040
21MP0005174_abnormal_tail_pigmentation2.08891781
22MP0003635_abnormal_synaptic_transmissio2.03523799
23MP0004133_heterotaxia2.00587399
24MP0001486_abnormal_startle_reflex1.97472210
25MP0009745_abnormal_behavioral_response1.94347052
26MP0008872_abnormal_physiological_respon1.92921351
27MP0001968_abnormal_touch/_nociception1.89991014
28MP0002210_abnormal_sex_determination1.83179313
29MP0008058_abnormal_DNA_repair1.81351726
30MP0003878_abnormal_ear_physiology1.79353046
31MP0005377_hearing/vestibular/ear_phenot1.79353046
32MP0002572_abnormal_emotion/affect_behav1.79063522
33MP0002736_abnormal_nociception_after1.72152382
34MP0002837_dystrophic_cardiac_calcinosis1.68751884
35MP0002064_seizures1.68737389
36MP0003646_muscle_fatigue1.66435922
37MP0003787_abnormal_imprinting1.64396937
38MP0002063_abnormal_learning/memory/cond1.63934333
39MP0000383_abnormal_hair_follicle1.62164201
40MP0002102_abnormal_ear_morphology1.61259209
41MP0002160_abnormal_reproductive_system1.60306636
42MP0005423_abnormal_somatic_nervous1.58491724
43MP0002638_abnormal_pupillary_reflex1.57828897
44MP0002557_abnormal_social/conspecific_i1.54858085
45MP0001501_abnormal_sleep_pattern1.53245159
46MP0002272_abnormal_nervous_system1.52159291
47MP0000566_synostosis1.49811231
48MP0002067_abnormal_sensory_capabilities1.46064920
49MP0002735_abnormal_chemical_nociception1.44126305
50MP0001145_abnormal_male_reproductive1.42174847
51MP0004885_abnormal_endolymph1.41995434
52MP0001502_abnormal_circadian_rhythm1.41644168
53MP0003879_abnormal_hair_cell1.38329446
54MP0005670_abnormal_white_adipose1.37332114
55MP0004147_increased_porphyrin_level1.37158709
56MP0005171_absent_coat_pigmentation1.35894604
57MP0005551_abnormal_eye_electrophysiolog1.35163086
58MP0002161_abnormal_fertility/fecundity1.32698664
59MP0002234_abnormal_pharynx_morphology1.31690986
60MP0000653_abnormal_sex_gland1.30808623
61MP0002822_catalepsy1.28826844
62MP0003011_delayed_dark_adaptation1.27624945
63MP0002095_abnormal_skin_pigmentation1.26704964
64MP0008995_early_reproductive_senescence1.25767957
65MP0005084_abnormal_gallbladder_morpholo1.23709302
66MP0002734_abnormal_mechanical_nocicepti1.22745781
67MP0001905_abnormal_dopamine_level1.22386819
68MP0000569_abnormal_digit_pigmentation1.21794034
69MP0000427_abnormal_hair_cycle1.21567238
70MP0004742_abnormal_vestibular_system1.17547862
71MP0004270_analgesia1.16640130
72MP0002733_abnormal_thermal_nociception1.16135574
73MP0008569_lethality_at_weaning1.13607151
74MP0003718_maternal_effect1.13445275
75MP0001440_abnormal_grooming_behavior1.11150619
76MP0001963_abnormal_hearing_physiology1.06812941
77MP0005195_abnormal_posterior_eye1.05134735
78MP0005394_taste/olfaction_phenotype1.02824491
79MP0005499_abnormal_olfactory_system1.02824491
80MP0002909_abnormal_adrenal_gland1.01560101
81MP0005085_abnormal_gallbladder_physiolo1.01409477
82MP0002184_abnormal_innervation1.01156148
83MP0002928_abnormal_bile_duct0.99760768
84MP0004808_abnormal_hematopoietic_stem0.98422716
85MP0000372_irregular_coat_pigmentation0.97514182
86MP0004145_abnormal_muscle_electrophysio0.97244855
87MP0004142_abnormal_muscle_tone0.97229883
88MP0002138_abnormal_hepatobiliary_system0.95558617
89MP0008004_abnormal_stomach_pH0.95307968
90MP0005671_abnormal_response_to0.95070619
91MP0000631_abnormal_neuroendocrine_gland0.94719371
92MP0005389_reproductive_system_phenotype0.91221045
93MP0005379_endocrine/exocrine_gland_phen0.90952853
94MP0001765_abnormal_ion_homeostasis0.89713368
95MP0001529_abnormal_vocalization0.88917842
96MP0001970_abnormal_pain_threshold0.87996674
97MP0000026_abnormal_inner_ear0.87989422
98MP0001485_abnormal_pinna_reflex0.86460023
99MP0002277_abnormal_respiratory_mucosa0.85299914
100MP0005253_abnormal_eye_physiology0.84370247
101MP0009780_abnormal_chondrocyte_physiolo0.83897873
102MP0005075_abnormal_melanosome_morpholog0.83522931
103MP0000778_abnormal_nervous_system0.82736246
104MP0003252_abnormal_bile_duct0.82500987
105MP0002876_abnormal_thyroid_physiology0.82075985
106MP0005636_abnormal_mineral_homeostasis0.81288657
107MP0006276_abnormal_autonomic_nervous0.81190328
108MP0002882_abnormal_neuron_morphology0.80528117
109MP0010678_abnormal_skin_adnexa0.79802604
110MP0004019_abnormal_vitamin_homeostasis0.79198133
111MP0001324_abnormal_eye_pigmentation0.79026028
112MP0000230_abnormal_systemic_arterial0.76838661
113MP0010386_abnormal_urinary_bladder0.75642516
114MP0004924_abnormal_behavior0.75431181
115MP0005386_behavior/neurological_phenoty0.75431181
116MP0008789_abnormal_olfactory_epithelium0.75288800
117MP0008775_abnormal_heart_ventricle0.74681866
118MP0005167_abnormal_blood-brain_barrier0.74507261
119MP0005083_abnormal_biliary_tract0.74182095
120MP0003122_maternal_imprinting0.73947446
121MP0004811_abnormal_neuron_physiology0.72253602
122MP0000955_abnormal_spinal_cord0.71871064
123MP0005332_abnormal_amino_acid0.71842590
124MP0002693_abnormal_pancreas_physiology0.71726692
125MP0010094_abnormal_chromosome_stability0.71604860
126MP0002752_abnormal_somatic_nervous0.70878208
127MP0005310_abnormal_salivary_gland0.70231799
128MP0002152_abnormal_brain_morphology0.68877474
129MP0006072_abnormal_retinal_apoptosis0.67530465
130MP0002229_neurodegeneration0.67083439
131MP0002132_abnormal_respiratory_system0.66718296
132MP0003183_abnormal_peptide_metabolism0.66549011
133MP0002075_abnormal_coat/hair_pigmentati0.66545574
134MP0008961_abnormal_basal_metabolism0.64461018
135MP0002938_white_spotting0.64222684
136MP0003045_fibrosis0.63236661

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.65773712
2Dynein arm defect of respiratory motile cilia (HP:0012255)9.18866612
3Absent/shortened dynein arms (HP:0200106)9.18866612
4Abnormal respiratory motile cilium physiology (HP:0012261)8.08067147
5Abnormal ciliary motility (HP:0012262)7.44634242
6Abnormal respiratory motile cilium morphology (HP:0005938)7.33320759
7Abnormal respiratory epithelium morphology (HP:0012253)7.33320759
8Rhinitis (HP:0012384)6.35413243
9Chronic bronchitis (HP:0004469)4.58044249
10Nephronophthisis (HP:0000090)4.17571362
11Bronchiectasis (HP:0002110)3.90431762
12Nasal polyposis (HP:0100582)3.45693431
13Abnormality of the renal medulla (HP:0100957)3.31163722
14Infertility (HP:0000789)3.30808107
15Medial flaring of the eyebrow (HP:0010747)3.30166425
16Molar tooth sign on MRI (HP:0002419)3.20234143
17Abnormality of midbrain morphology (HP:0002418)3.20234143
18Pancreatic fibrosis (HP:0100732)3.19079642
19Congenital stationary night blindness (HP:0007642)3.13099036
20True hermaphroditism (HP:0010459)3.08406098
21Chronic hepatic failure (HP:0100626)2.75017955
22Median cleft lip (HP:0000161)2.73222887
23Tubulointerstitial nephritis (HP:0001970)2.68698357
24Type II lissencephaly (HP:0007260)2.67165084
25Sclerocornea (HP:0000647)2.67119886
26Bronchitis (HP:0012387)2.66426846
27Pancreatic cysts (HP:0001737)2.65708154
28Abnormality of the nasal mucosa (HP:0000433)2.65343720
29Postaxial foot polydactyly (HP:0001830)2.61489264
30Recurrent sinusitis (HP:0011108)2.59132869
31Focal motor seizures (HP:0011153)2.55489788
32Febrile seizures (HP:0002373)2.50574281
33Congenital primary aphakia (HP:0007707)2.47748258
34Congenital hepatic fibrosis (HP:0002612)2.44923194
35Chronic sinusitis (HP:0011109)2.44768314
36Gait imbalance (HP:0002141)2.44538127
37Abnormal rod and cone electroretinograms (HP:0008323)2.42467430
38Nephrogenic diabetes insipidus (HP:0009806)2.40218512
39Abolished electroretinogram (ERG) (HP:0000550)2.38408285
40Furrowed tongue (HP:0000221)2.37574508
41Decreased circulating renin level (HP:0003351)2.35078333
42Recurrent otitis media (HP:0000403)2.29898826
43Attenuation of retinal blood vessels (HP:0007843)2.28512809
44Elfin facies (HP:0004428)2.27668054
45Absent rod-and cone-mediated responses on ERG (HP:0007688)2.26447765
46Gaze-evoked nystagmus (HP:0000640)2.25015979
47Cystic liver disease (HP:0006706)2.18477479
48Epileptic encephalopathy (HP:0200134)2.12858562
49Hyperventilation (HP:0002883)2.12286958
50Abnormal hair whorl (HP:0010721)2.11880043
51Postaxial hand polydactyly (HP:0001162)2.10643947
52Pendular nystagmus (HP:0012043)2.08478244
53Renovascular hypertension (HP:0100817)2.08203390
54Chromosomal breakage induced by crosslinking agents (HP:0003221)2.07661865
55Supernumerary spleens (HP:0009799)2.06133053
56Hyperacusis (HP:0010780)2.04805319
57Progressive cerebellar ataxia (HP:0002073)2.03565544
58Aplasia/Hypoplasia of the tongue (HP:0010295)1.98162124
59Facial cleft (HP:0002006)1.97485046
60Aplasia/Hypoplasia of the tibia (HP:0005772)1.95386558
61Oculomotor apraxia (HP:0000657)1.95140083
62Aplasia/Hypoplasia of the spleen (HP:0010451)1.94479329
63Polyuria (HP:0000103)1.93620329
64Abnormality of the renal cortex (HP:0011035)1.93154695
65Preaxial hand polydactyly (HP:0001177)1.92691249
66Cerebellar dysplasia (HP:0007033)1.90668403
67Occipital encephalocele (HP:0002085)1.89318882
68Poor coordination (HP:0002370)1.89152379
69Broad-based gait (HP:0002136)1.87339868
70Renal dysplasia (HP:0000110)1.84057283
71Overriding aorta (HP:0002623)1.82338830
72Asplenia (HP:0001746)1.81489141
73Flat cornea (HP:0007720)1.80629918
74Genital tract atresia (HP:0001827)1.78536507
75Abnormality of the carotid arteries (HP:0005344)1.77381047
76Bony spicule pigmentary retinopathy (HP:0007737)1.75600778
77Keratoconus (HP:0000563)1.74053767
78Increased corneal curvature (HP:0100692)1.74053767
79Tubular atrophy (HP:0000092)1.73887953
80Inability to walk (HP:0002540)1.73450378
81Abnormality of macular pigmentation (HP:0008002)1.73111979
82Vaginal atresia (HP:0000148)1.72724312
83Lissencephaly (HP:0001339)1.71722069
84Dyschromatopsia (HP:0007641)1.69627598
85Genetic anticipation (HP:0003743)1.69112454
86Decreased electroretinogram (ERG) amplitude (HP:0000654)1.68748520
87Abnormality of molar (HP:0011077)1.67892587
88Abnormality of molar morphology (HP:0011070)1.67892587
89Absent speech (HP:0001344)1.67481570
90Abnormality of the dental root (HP:0006486)1.66084672
91Taurodontia (HP:0000679)1.66084672
92Abnormality of permanent molar morphology (HP:0011071)1.66084672
93Renal cortical cysts (HP:0000803)1.65975127
94Aplasia/Hypoplasia of the lens (HP:0008063)1.64415414
95Chronic otitis media (HP:0000389)1.64132884
96Abnormal biliary tract physiology (HP:0012439)1.63326328
97Bile duct proliferation (HP:0001408)1.63326328
98Chromsome breakage (HP:0040012)1.62694184
99Renal duplication (HP:0000075)1.61292452
100Male pseudohermaphroditism (HP:0000037)1.60742573
101Bifid tongue (HP:0010297)1.60540161
102Polydipsia (HP:0001959)1.60346408
103Abnormal drinking behavior (HP:0030082)1.60346408
104Decreased central vision (HP:0007663)1.60131100
105Large for gestational age (HP:0001520)1.59674231
106Stage 5 chronic kidney disease (HP:0003774)1.58723869
107Abnormality of renin-angiotensin system (HP:0000847)1.57152105
108Abnormal urine output (HP:0012590)1.56511595
109Short tibia (HP:0005736)1.56289181
110Insomnia (HP:0100785)1.55405001
111Acute necrotizing encephalopathy (HP:0006965)1.54498634
112Narrow forehead (HP:0000341)1.53991173
113Intestinal atresia (HP:0011100)1.53754036
114Absent eyebrow (HP:0002223)1.53586409
115Astigmatism (HP:0000483)1.52687313
116Aganglionic megacolon (HP:0002251)1.51666638
117Fibular hypoplasia (HP:0003038)1.51614927
118Aplasia/Hypoplasia of the uvula (HP:0010293)1.51246800
119Abnormality of the pons (HP:0007361)1.50447954
120Hypoplasia of the pons (HP:0012110)1.49425491
121Polycystic kidney dysplasia (HP:0000113)1.48917603
122Retinal dysplasia (HP:0007973)1.48629671
123Abnormality of the dental pulp (HP:0006479)1.48151621
124Mitochondrial inheritance (HP:0001427)1.47623468
125Stomach cancer (HP:0012126)1.47534790
126Hemiparesis (HP:0001269)1.46806408
127Abnormality of ocular smooth pursuit (HP:0000617)1.46267117
128Abnormality of renal excretion (HP:0011036)1.46128788
129Hyperactive renin-angiotensin system (HP:0000841)1.46098588
1303-Methylglutaconic aciduria (HP:0003535)1.45334496
131Congenital, generalized hypertrichosis (HP:0004540)1.44695188
132Chorioretinal atrophy (HP:0000533)1.44476577
133Nephropathy (HP:0000112)1.41644429
134Focal seizures (HP:0007359)1.39661186
135Recurrent bronchitis (HP:0002837)1.38681910
136Tubulointerstitial abnormality (HP:0001969)1.38542255
137Clubbing of toes (HP:0100760)1.37291268
138Anencephaly (HP:0002323)1.36622196
139Short thorax (HP:0010306)1.36458043
140Truncal ataxia (HP:0002078)1.35808788
141Optic nerve coloboma (HP:0000588)1.33314035
142Abnormality of the diencephalon (HP:0010662)1.31776250
143Retinitis pigmentosa (HP:0000510)1.31744743
144Gonadotropin excess (HP:0000837)1.31223913

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.19268287
2MAPK153.69532407
3PDK43.63755858
4PDK33.63755858
5TLK13.51665889
6SIK33.30273263
7CASK2.78599424
8MAP4K22.77471082
9TNIK2.67271597
10NTRK32.58246868
11MAP2K72.32938551
12TXK2.31959491
13WNK32.26848954
14PDK22.26011987
15PRKD32.22655547
16MST42.12702398
17PNCK2.02892311
18ACVR1B2.02164051
19TAOK31.94089051
20INSRR1.90740151
21PRPF4B1.89227010
22NUAK11.88373437
23YES11.81189337
24OXSR11.75920536
25EPHA41.73559663
26NTRK21.64087349
27GRK71.60401719
28MUSK1.58402011
29SIK21.56102945
30NEK61.51884752
31CDK31.49570102
32BMPR1B1.47893221
33RIPK41.47187550
34STK391.46769771
35SGK21.37371901
36GRK11.34671728
37TNK21.34562628
38ADRBK21.33783064
39PIK3CA1.31084805
40STK161.28197361
41CAMKK21.27208427
42MAPK131.26850854
43AKT31.22121933
44ADRBK11.19264581
45ZAK1.17466810
46MAPKAPK31.17333424
47VRK11.14327994
48PINK11.13940128
49MAP3K91.13551978
50WNK11.11182884
51ICK1.09831917
52STK381.05960313
53PTK2B1.05571453
54BMPR21.04353072
55CAMK11.03334131
56NME11.01464149
57CCNB11.00359329
58TGFBR20.99506156
59TGFBR10.98783464
60DYRK20.98579219
61IRAK30.97466319
62BCKDK0.97152011
63PAK30.96030348
64TESK10.95061703
65MAP3K40.88278049
66CAMK1G0.87712662
67BCR0.86594023
68CAMKK10.83054692
69FES0.82177968
70SGK4940.79846041
71SGK2230.79846041
72TIE10.77553716
73PHKG20.77236196
74PHKG10.77236196
75BRD40.76423404
76HCK0.73750083
77PRKCQ0.73106297
78STK38L0.72901313
79MKNK20.72331007
80MAPK70.72265545
81WNK40.71393684
82TRIM280.71198799
83PRKCG0.70994461
84SGK30.70479706
85MAP3K120.69818367
86CSNK1G20.68413790
87MARK20.66765446
88ITK0.61656646
89CSNK1G30.60915727
90CAMK40.60756234
91PLK40.60673897
92CDK190.59455783
93IKBKB0.58728088
94KIT0.58718293
95CSNK1G10.57632601
96SYK0.57413664
97CLK10.57201623
98MINK10.55368869
99RPS6KA50.55177592
100PRKCI0.54423183
101CDC42BPA0.54134334
102ATR0.53717010
103CSNK1A1L0.53330348
104TEC0.53124855
105MAP2K60.51935485
106PRKACA0.51770282
107NEK20.50722129
108NLK0.50403327
109BRSK20.50004714
110ZAP700.49959233
111EIF2AK20.49446008
112PASK0.48845611
113IRAK10.48508160
114PLK20.48349052
115DAPK20.48269779
116CAMK2A0.46290063
117PRKG10.45233258
118PRKD20.44938454
119MAPKAPK50.44367970
120MAP3K130.43779182
121MAP4K10.43632596
122PRKAA20.41641586
123PRKAA10.41531170
124GRK50.40946204
125STK110.40904953
126PKN10.40744391
127ERBB20.40203087
128PRKCZ0.39774805
129PRKCA0.39774355
130ERBB30.37219660
131SGK10.36916067
132FGFR20.36902505
133LYN0.35146167
134BTK0.34527627
135CSNK1D0.34405111
136PDK10.33918876
137CHUK0.33099893
138DYRK1A0.33017805
139LCK0.32861451
140CDK90.31997034
141FER0.31882284
142IRAK20.31850873
143RPS6KB10.31334354
144DAPK10.30717117
145MARK30.30220973
146PRKCE0.30176294
147EPHA30.28858006
148MARK10.28190720
149PLK10.27593156
150CSNK1A10.27579342
151IRAK40.27342043
152CDK50.27036538
153TRPM70.26457225
154ABL10.26132223
155CHEK20.25635814
156MAP2K10.24956916

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.00654303
2Olfactory transduction_Homo sapiens_hsa047402.70923575
3Caffeine metabolism_Homo sapiens_hsa002322.33361334
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.23650257
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.20240531
6Morphine addiction_Homo sapiens_hsa050322.19084903
7Nitrogen metabolism_Homo sapiens_hsa009102.17840466
8Amphetamine addiction_Homo sapiens_hsa050312.17591731
9Taste transduction_Homo sapiens_hsa047422.09654825
10Circadian entrainment_Homo sapiens_hsa047132.08506195
11Butanoate metabolism_Homo sapiens_hsa006502.08101376
12Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.07242579
13Glutamatergic synapse_Homo sapiens_hsa047242.03759732
14Fanconi anemia pathway_Homo sapiens_hsa034601.97375338
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.96094164
16Chemical carcinogenesis_Homo sapiens_hsa052041.94863083
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.88910619
18Oxidative phosphorylation_Homo sapiens_hsa001901.88480359
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.85253818
20Synaptic vesicle cycle_Homo sapiens_hsa047211.79134110
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.78404330
22Insulin secretion_Homo sapiens_hsa049111.76209534
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.76064409
24Tryptophan metabolism_Homo sapiens_hsa003801.74458904
25Long-term potentiation_Homo sapiens_hsa047201.74285347
26Selenocompound metabolism_Homo sapiens_hsa004501.74070686
27Calcium signaling pathway_Homo sapiens_hsa040201.67501160
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.58930119
29Basal transcription factors_Homo sapiens_hsa030221.58239410
30Phosphatidylinositol signaling system_Homo sapiens_hsa040701.57528404
31Histidine metabolism_Homo sapiens_hsa003401.53985817
32Phototransduction_Homo sapiens_hsa047441.51933541
33beta-Alanine metabolism_Homo sapiens_hsa004101.50747602
34Renin secretion_Homo sapiens_hsa049241.50393488
35Serotonergic synapse_Homo sapiens_hsa047261.50274345
36GABAergic synapse_Homo sapiens_hsa047271.49055362
37Retinol metabolism_Homo sapiens_hsa008301.43043893
38Parkinsons disease_Homo sapiens_hsa050121.32950274
39Cocaine addiction_Homo sapiens_hsa050301.29888494
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.28574165
41Salivary secretion_Homo sapiens_hsa049701.27887911
42Aldosterone synthesis and secretion_Homo sapiens_hsa049251.27467709
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.26228160
44RNA polymerase_Homo sapiens_hsa030201.25808415
45Dopaminergic synapse_Homo sapiens_hsa047281.21938504
46Protein export_Homo sapiens_hsa030601.21625979
47Peroxisome_Homo sapiens_hsa041461.20364559
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.17792312
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.17362289
50Primary bile acid biosynthesis_Homo sapiens_hsa001201.15673919
51Homologous recombination_Homo sapiens_hsa034401.13096875
52Gastric acid secretion_Homo sapiens_hsa049711.12355697
53Propanoate metabolism_Homo sapiens_hsa006401.12060734
54Dorso-ventral axis formation_Homo sapiens_hsa043201.11573252
55Asthma_Homo sapiens_hsa053101.10124711
56Collecting duct acid secretion_Homo sapiens_hsa049661.09983901
57cAMP signaling pathway_Homo sapiens_hsa040241.09656975
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.08669568
59Primary immunodeficiency_Homo sapiens_hsa053401.08279153
60Sphingolipid metabolism_Homo sapiens_hsa006001.08197003
61Cholinergic synapse_Homo sapiens_hsa047251.04783976
62Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.02583956
63Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01919178
64Cardiac muscle contraction_Homo sapiens_hsa042601.01370019
65Inositol phosphate metabolism_Homo sapiens_hsa005620.99293084
66Circadian rhythm_Homo sapiens_hsa047100.98049557
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97953414
68Oxytocin signaling pathway_Homo sapiens_hsa049210.95694801
69Tyrosine metabolism_Homo sapiens_hsa003500.92517272
70Long-term depression_Homo sapiens_hsa047300.90730041
71Regulation of autophagy_Homo sapiens_hsa041400.90672829
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.87514844
73Phenylalanine metabolism_Homo sapiens_hsa003600.87468667
74Glucagon signaling pathway_Homo sapiens_hsa049220.86395707
75cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86364906
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.85791364
77One carbon pool by folate_Homo sapiens_hsa006700.84799058
78Type I diabetes mellitus_Homo sapiens_hsa049400.83753676
79Alzheimers disease_Homo sapiens_hsa050100.83508490
80Type II diabetes mellitus_Homo sapiens_hsa049300.83155801
81Ether lipid metabolism_Homo sapiens_hsa005650.82580484
82Other glycan degradation_Homo sapiens_hsa005110.80925653
83Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.79391043
84RNA degradation_Homo sapiens_hsa030180.75855439
85ABC transporters_Homo sapiens_hsa020100.75738369
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75621824
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.75270882
88Rheumatoid arthritis_Homo sapiens_hsa053230.74635855
89Hematopoietic cell lineage_Homo sapiens_hsa046400.73441959
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73241023
91Fat digestion and absorption_Homo sapiens_hsa049750.73072237
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72056012
93Autoimmune thyroid disease_Homo sapiens_hsa053200.70476761
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.70249135
95Intestinal immune network for IgA production_Homo sapiens_hsa046720.70175071
96Estrogen signaling pathway_Homo sapiens_hsa049150.68964447
97Huntingtons disease_Homo sapiens_hsa050160.68608822
98Purine metabolism_Homo sapiens_hsa002300.67881988
99T cell receptor signaling pathway_Homo sapiens_hsa046600.67726268
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.67487380
101MAPK signaling pathway_Homo sapiens_hsa040100.65640432
102alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65071541
103Fatty acid degradation_Homo sapiens_hsa000710.64856506
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64779878
105Oocyte meiosis_Homo sapiens_hsa041140.63804164
106Measles_Homo sapiens_hsa051620.63719636
107Arachidonic acid metabolism_Homo sapiens_hsa005900.63275738
108Glycerolipid metabolism_Homo sapiens_hsa005610.63190922
109Wnt signaling pathway_Homo sapiens_hsa043100.62967507
110Metabolic pathways_Homo sapiens_hsa011000.62661838
111N-Glycan biosynthesis_Homo sapiens_hsa005100.62487220
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62460728
113Osteoclast differentiation_Homo sapiens_hsa043800.61202393
114mRNA surveillance pathway_Homo sapiens_hsa030150.60327042
115Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59737364
116Allograft rejection_Homo sapiens_hsa053300.59257256
117African trypanosomiasis_Homo sapiens_hsa051430.58708171
118Alcoholism_Homo sapiens_hsa050340.58074125
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57659742
120GnRH signaling pathway_Homo sapiens_hsa049120.57454162
121ErbB signaling pathway_Homo sapiens_hsa040120.56674099
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55845455
123Linoleic acid metabolism_Homo sapiens_hsa005910.55103273
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.53980843
125Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.52450785
126Toll-like receptor signaling pathway_Homo sapiens_hsa046200.50765947
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50252280
128Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50028135
129Graft-versus-host disease_Homo sapiens_hsa053320.49459028
130Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48799246
131B cell receptor signaling pathway_Homo sapiens_hsa046620.48729969
132Vitamin B6 metabolism_Homo sapiens_hsa007500.48725220
133Pancreatic secretion_Homo sapiens_hsa049720.47142512
134Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46276483
135Glutathione metabolism_Homo sapiens_hsa004800.45440006
136Influenza A_Homo sapiens_hsa051640.45435585
137Vitamin digestion and absorption_Homo sapiens_hsa049770.44762467
138Chemokine signaling pathway_Homo sapiens_hsa040620.44540024
139Ras signaling pathway_Homo sapiens_hsa040140.44511378
140Phospholipase D signaling pathway_Homo sapiens_hsa040720.44332923
141Mineral absorption_Homo sapiens_hsa049780.43918414
142Melanogenesis_Homo sapiens_hsa049160.43836893
143Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.43792717
144Ovarian steroidogenesis_Homo sapiens_hsa049130.43551951
145Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.43319923
146Sulfur relay system_Homo sapiens_hsa041220.41368991
147Drug metabolism - other enzymes_Homo sapiens_hsa009830.38781342
148Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37391208
149Pyrimidine metabolism_Homo sapiens_hsa002400.36295417
150Fatty acid biosynthesis_Homo sapiens_hsa000610.35645617
151Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35398473
152Cyanoamino acid metabolism_Homo sapiens_hsa004600.34726099
153Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.31760240

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