CFAP77

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right pattern formation (GO:0060972)8.99307725
2ventricular system development (GO:0021591)6.81878136
3cilium organization (GO:0044782)6.33400504
4left/right axis specification (GO:0070986)6.32309370
5cilium assembly (GO:0042384)6.20514795
6microtubule bundle formation (GO:0001578)6.12962709
7presynaptic membrane assembly (GO:0097105)5.87765336
8primary alcohol catabolic process (GO:0034310)5.66472784
9omega-hydroxylase P450 pathway (GO:0097267)5.59086009
10postsynaptic membrane organization (GO:0001941)5.10651450
11vitamin transmembrane transport (GO:0035461)4.95160091
12cellular component assembly involved in morphogenesis (GO:0010927)4.86917135
13ethanol metabolic process (GO:0006067)4.83604671
14presynaptic membrane organization (GO:0097090)4.82306823
15cilium morphogenesis (GO:0060271)4.81705391
16protein K11-linked deubiquitination (GO:0035871)4.69175956
17protein heterotetramerization (GO:0051290)4.68074472
18axonemal dynein complex assembly (GO:0070286)4.63532465
19microtubule-based movement (GO:0007018)4.56247967
20cell projection assembly (GO:0030031)4.55402790
21cilium movement (GO:0003341)4.44496185
22regulation of microtubule-based movement (GO:0060632)4.43809367
23diterpenoid biosynthetic process (GO:0016102)4.41229700
24lung epithelium development (GO:0060428)4.28729652
25sperm capacitation (GO:0048240)4.28473721
26establishment of apical/basal cell polarity (GO:0035089)4.07326059
27ribosomal small subunit biogenesis (GO:0042274)4.07195282
28proteasome assembly (GO:0043248)4.05898892
29sperm motility (GO:0030317)4.04703433
30generation of neurons (GO:0048699)3.98561626
31response to xenobiotic stimulus (GO:0009410)3.98447082
32epithelial cilium movement (GO:0003351)3.94415191
33microtubule depolymerization (GO:0007019)3.90314092
34carnitine metabolic process (GO:0009437)3.88738885
35glomerular epithelial cell development (GO:0072310)3.88643272
36GTP biosynthetic process (GO:0006183)3.88459820
37tolerance induction (GO:0002507)3.85727980
38one-carbon compound transport (GO:0019755)3.83278567
39axoneme assembly (GO:0035082)3.81650104
40establishment or maintenance of monopolar cell polarity (GO:0061339)3.81154770
41establishment of monopolar cell polarity (GO:0061162)3.81154770
42pyrimidine-containing compound transmembrane transport (GO:0072531)3.73932537
43negative regulation of T cell differentiation in thymus (GO:0033085)3.71995787
44viral transcription (GO:0019083)3.67751611
45interferon-gamma production (GO:0032609)3.66313594
46regulation of histone H3-K27 methylation (GO:0061085)3.66173878
47ethanol oxidation (GO:0006069)3.65665020
48microtubule polymerization or depolymerization (GO:0031109)3.63333735
49lateral ventricle development (GO:0021670)3.57601074
50retinoic acid metabolic process (GO:0042573)3.50829138
51DNA deamination (GO:0045006)3.49817273
52ribosomal large subunit biogenesis (GO:0042273)3.47490684
53smoothened signaling pathway (GO:0007224)3.41822517
54negative regulation of circadian rhythm (GO:0042754)3.38798425
55regulation of pigment cell differentiation (GO:0050932)3.38555944
56translational termination (GO:0006415)3.37781101
57DNA ligation (GO:0006266)3.37573246
58negative regulation of immunoglobulin mediated immune response (GO:0002890)3.37507787
59negative regulation of B cell mediated immunity (GO:0002713)3.37507787
60epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.34971674
61negative regulation of humoral immune response (GO:0002921)3.33293601
62regulation of interleukin-5 production (GO:0032674)3.31057842
63regulation of germinal center formation (GO:0002634)3.28597642
64establishment of planar polarity (GO:0001736)3.24861057
65establishment of tissue polarity (GO:0007164)3.24861057
66DNA damage response, detection of DNA damage (GO:0042769)3.23984184
67negative regulation of execution phase of apoptosis (GO:1900118)3.23045485
68nonmotile primary cilium assembly (GO:0035058)3.22938615
69regulation of T-helper 1 cell differentiation (GO:0045625)3.21493441
70nucleoside diphosphate phosphorylation (GO:0006165)3.21222877
71retinal cone cell development (GO:0046549)3.20621638
72ribosomal small subunit assembly (GO:0000028)3.19434824
73determination of left/right symmetry (GO:0007368)3.18862235
74cytoplasmic microtubule organization (GO:0031122)3.17874847
75positive regulation of hair follicle development (GO:0051798)3.16295541
76positive regulation of hair cycle (GO:0042635)3.16295541
77SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.15838779
78positive regulation of smoothened signaling pathway (GO:0045880)3.14271170
79centriole assembly (GO:0098534)3.13804995
80UTP biosynthetic process (GO:0006228)3.12146671
81cotranslational protein targeting to membrane (GO:0006613)3.10940888
82terpenoid biosynthetic process (GO:0016114)3.10187357
83carnitine transmembrane transport (GO:1902603)3.09819252
84regulation of collateral sprouting (GO:0048670)3.09526224
85protein targeting to ER (GO:0045047)3.09216572
86response to folic acid (GO:0051593)3.08298498
87regulation of metalloenzyme activity (GO:0048552)3.08184824
88determination of bilateral symmetry (GO:0009855)3.05215275
89negative regulation of leukocyte chemotaxis (GO:0002689)3.02677515
90amino-acid betaine metabolic process (GO:0006577)3.02037936
91specification of symmetry (GO:0009799)2.99861252
92cysteine metabolic process (GO:0006534)2.97587167
93protein localization to endoplasmic reticulum (GO:0070972)2.92252223
94amino sugar catabolic process (GO:0046348)2.92103906
95cilium or flagellum-dependent cell motility (GO:0001539)2.91445247
96melanin metabolic process (GO:0006582)2.89593453
97hematopoietic stem cell proliferation (GO:0071425)2.89340696
98regulation of interleukin-13 production (GO:0032656)2.87541431
99intra-S DNA damage checkpoint (GO:0031573)2.87294335
100retinal rod cell development (GO:0046548)2.86997187
101establishment of protein localization to endoplasmic reticulum (GO:0072599)2.86881277
102facial nerve structural organization (GO:0021612)2.86731320
103regulation of appetite (GO:0032098)2.86721431
104negative regulation of alpha-beta T cell differentiation (GO:0046639)2.84860414
105exogenous drug catabolic process (GO:0042738)2.84507463
106guanosine-containing compound biosynthetic process (GO:1901070)2.84450425
107organic cation transport (GO:0015695)2.83828606
108positive regulation of tolerance induction (GO:0002645)2.83671138
109organelle assembly (GO:0070925)2.83206127
110mesenchymal cell differentiation involved in kidney development (GO:0072161)2.82593078
111mesenchymal cell differentiation involved in renal system development (GO:2001012)2.82593078
112mesonephros development (GO:0001823)2.82562763
113negative regulation of inclusion body assembly (GO:0090084)2.80845828
114negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.79651818
115negative regulation of T-helper cell differentiation (GO:0045623)2.79651818
116amino-acid betaine transport (GO:0015838)2.78628584
117carnitine transport (GO:0015879)2.78628584
118filopodium assembly (GO:0046847)2.77196093
119serotonin receptor signaling pathway (GO:0007210)2.76441698
120negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.76195207
121microtubule-based process (GO:0007017)2.75916155
122regulation of microtubule depolymerization (GO:0031114)2.75575697
123photoreceptor cell maintenance (GO:0045494)2.74663411
124lateral sprouting from an epithelium (GO:0060601)2.72437662
125regulation of autophagic vacuole assembly (GO:2000785)2.71630742
126motile cilium assembly (GO:0044458)2.70479681
127superoxide anion generation (GO:0042554)2.69453398
128regulation of T-helper 2 cell differentiation (GO:0045628)2.68827613
129regulation of timing of cell differentiation (GO:0048505)2.65473922
130response to peptidoglycan (GO:0032494)2.65465966
131N-acetylneuraminate metabolic process (GO:0006054)2.63513164
132glutathione derivative metabolic process (GO:1901685)2.63249047
133glutathione derivative biosynthetic process (GO:1901687)2.63249047
134regulation of development, heterochronic (GO:0040034)2.63188990
135cranial nerve morphogenesis (GO:0021602)2.62960771
136regulation of male gonad development (GO:2000018)2.61919323
137translational elongation (GO:0006414)2.61914436
138thyroid hormone metabolic process (GO:0042403)2.61344861
139intraciliary transport (GO:0042073)2.61265822
140regulation of cilium movement (GO:0003352)2.60196001
141deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.57075386
142tRNA modification (GO:0006400)2.57000222
143centriole replication (GO:0007099)2.56786435
144myoblast migration (GO:0051451)2.56629253
145mature B cell differentiation (GO:0002335)2.56308152
146quaternary ammonium group transport (GO:0015697)2.55620607
147CTP metabolic process (GO:0046036)2.54949600
148CTP biosynthetic process (GO:0006241)2.54949600
149viral life cycle (GO:0019058)2.54705452
150positive regulation of T-helper 1 type immune response (GO:0002827)2.54254519
151regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.53905824
152regulation of smoothened signaling pathway (GO:0008589)2.53535114
153regulation of double-strand break repair via homologous recombination (GO:0010569)2.51496462
154termination of RNA polymerase III transcription (GO:0006386)2.50935626
155transcription elongation from RNA polymerase III promoter (GO:0006385)2.50935626
156retinol metabolic process (GO:0042572)2.50858752
157negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.49886464
158negative regulation of interleukin-8 production (GO:0032717)2.49305374
159viral genome replication (GO:0019079)2.49124966
160regulation of interleukin-6 biosynthetic process (GO:0045408)2.48721262
161microtubule severing (GO:0051013)2.48518284
162primary alcohol metabolic process (GO:0034308)2.48334116
163cellular protein complex disassembly (GO:0043624)2.47506187
164positive regulation of protein kinase C signaling (GO:0090037)2.47066915
165respiratory chain complex IV assembly (GO:0008535)2.44999071
166spermatid nucleus differentiation (GO:0007289)2.41903867
167cellular response to exogenous dsRNA (GO:0071360)2.39237052
168pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.38727261
169androgen biosynthetic process (GO:0006702)2.38644890
170UTP metabolic process (GO:0046051)2.37382675
171neurotransmitter-gated ion channel clustering (GO:0072578)2.36490973
172regulation of interleukin-8 secretion (GO:2000482)2.35963510
173dendritic cell chemotaxis (GO:0002407)2.35486939
174sequestering of actin monomers (GO:0042989)2.35136080
175GMP metabolic process (GO:0046037)2.34339498
176protein localization to cilium (GO:0061512)2.33628328
177response to increased oxygen levels (GO:0036296)2.33446112
178response to hyperoxia (GO:0055093)2.33446112
179positive regulation of developmental pigmentation (GO:0048087)2.32862797
180negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.31693107
181negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.30176137
182membrane assembly (GO:0071709)2.29640143
183regulation of stem cell maintenance (GO:2000036)2.28469764
184telomere maintenance via semi-conservative replication (GO:0032201)2.26117653
185nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.26034441
186positive regulation of T-helper cell differentiation (GO:0045624)2.25653697
187cell differentiation involved in metanephros development (GO:0072202)2.23887545

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.01453827
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.80047318
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.03942574
4IRF1_19129219_ChIP-ChIP_H3396_Human3.69386148
5DROSHA_22980978_ChIP-Seq_HELA_Human3.62038296
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse3.34913867
7FLI1_27457419_Chip-Seq_LIVER_Mouse3.27323101
8EZH2_22144423_ChIP-Seq_EOC_Human3.26855158
9PCGF2_27294783_Chip-Seq_ESCs_Mouse3.22385059
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.99245816
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.91000652
12ESR1_20079471_ChIP-ChIP_T-47D_Human2.49810429
13FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.40215337
14KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.38465998
15KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.38465998
16KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.38465998
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.32775427
18SUZ12_27294783_Chip-Seq_NPCs_Mouse2.28470851
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.22577573
20BMI1_23680149_ChIP-Seq_NPCS_Mouse2.17536727
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.13209070
22NFE2_27457419_Chip-Seq_LIVER_Mouse2.12657674
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.06747062
24ZFP57_27257070_Chip-Seq_ESCs_Mouse2.00004038
25GBX2_23144817_ChIP-Seq_PC3_Human1.93083552
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.91997857
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.86868514
28PIAS1_25552417_ChIP-Seq_VCAP_Human1.85565801
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.84365212
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81305181
31HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81304395
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.80796469
33RNF2_27304074_Chip-Seq_NSC_Mouse1.80305059
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.72578195
35NR3C1_21868756_ChIP-Seq_MCF10A_Human1.69953271
36EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.68373063
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.68323942
38BP1_19119308_ChIP-ChIP_Hs578T_Human1.67494814
39POU5F1_16153702_ChIP-ChIP_HESCs_Human1.66709746
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.65765529
41NMYC_18555785_Chip-Seq_ESCs_Mouse1.64716466
42EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.63191043
43SUZ12_18555785_Chip-Seq_ESCs_Mouse1.63117419
44STAT3_18555785_Chip-Seq_ESCs_Mouse1.61476758
45RUNX1_27457419_Chip-Seq_LIVER_Mouse1.59525567
46AR_21572438_ChIP-Seq_LNCaP_Human1.59095557
47P53_22387025_ChIP-Seq_ESCs_Mouse1.58286112
48P300_18555785_Chip-Seq_ESCs_Mouse1.57343276
49TP53_18474530_ChIP-ChIP_U2OS_Human1.57081325
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.56232739
51SMAD4_21799915_ChIP-Seq_A2780_Human1.56175899
52STAT1_20625510_ChIP-Seq_HELA_Human1.55406556
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.53096924
54E2F1_18555785_Chip-Seq_ESCs_Mouse1.51655689
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51611726
56VDR_22108803_ChIP-Seq_LS180_Human1.46178809
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.46167162
58EZH2_27294783_Chip-Seq_ESCs_Mouse1.45584935
59PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.44779033
60ZFX_18555785_Chip-Seq_ESCs_Mouse1.44482620
61FOXM1_26456572_ChIP-Seq_MCF-7_Human1.44431463
62TP53_16413492_ChIP-PET_HCT116_Human1.44389250
63IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.43544116
64SOX2_18555785_Chip-Seq_ESCs_Mouse1.41281248
65JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.40362220
66KLF4_18555785_Chip-Seq_ESCs_Mouse1.40021635
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39055594
68GABP_17652178_ChIP-ChIP_JURKAT_Human1.38397210
69SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.37742536
70CMYC_18555785_Chip-Seq_ESCs_Mouse1.37506293
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37268724
72JARID2_20064375_ChIP-Seq_MESCs_Mouse1.37227437
73GATA1_26923725_Chip-Seq_HPCs_Mouse1.36287398
74CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.36047217
75EZH2_27304074_Chip-Seq_ESCs_Mouse1.35591160
76OCT4_18555785_Chip-Seq_ESCs_Mouse1.35107914
77PHF8_20622853_ChIP-Seq_HELA_Human1.34012080
78YY1_21170310_ChIP-Seq_MESCs_Mouse1.32242561
79ESRRB_18555785_Chip-Seq_ESCs_Mouse1.31963450
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.31893899
81CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.30858475
82ETV1_20927104_ChIP-Seq_GIST48_Human1.29519637
83NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.29515360
84PU1_27457419_Chip-Seq_LIVER_Mouse1.29264522
85CTBP1_25329375_ChIP-Seq_LNCAP_Human1.28718360
86SMC4_20622854_ChIP-Seq_HELA_Human1.28507290
87AHR_22903824_ChIP-Seq_MCF-7_Human1.28348105
88WDR5_24793694_ChIP-Seq_LNCAP_Human1.28294726
89TP63_23658742_ChIP-Seq_EP156T_Human1.28182070
90PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.27585973
91FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.27291697
92ARNT_22903824_ChIP-Seq_MCF-7_Human1.27110352
93CTCF_18555785_Chip-Seq_ESCs_Mouse1.26216205
94CTBP2_25329375_ChIP-Seq_LNCAP_Human1.25770412
95AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.25551186
96CTCF_20526341_ChIP-Seq_ESCs_Human1.25313903
97EED_16625203_ChIP-ChIP_MESCs_Mouse1.24204825
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23578182
99CRX_20693478_ChIP-Seq_RETINA_Mouse1.22750242
100POU3F2_20337985_ChIP-ChIP_501MEL_Human1.21920180
101SMAD1_18555785_Chip-Seq_ESCs_Mouse1.21818117
102KAP1_22055183_ChIP-Seq_ESCs_Mouse1.20380159
103SMAD3_21741376_ChIP-Seq_EPCs_Human1.19515072
104AR_25329375_ChIP-Seq_VCAP_Human1.19123552
105SOX9_24532713_ChIP-Seq_HFSC_Mouse1.18589005
106MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17654350
107STAT3_23295773_ChIP-Seq_U87_Human1.17016276
108TAF15_26573619_Chip-Seq_HEK293_Human1.16031352
109TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15857757
110SMAD4_21741376_ChIP-Seq_EPCs_Human1.15616132
111TBL1_22424771_ChIP-Seq_293T_Human1.15524116
112SUZ12_27294783_Chip-Seq_ESCs_Mouse1.15279153
113HNFA_21074721_ChIP-Seq_CACO-2_Human1.15182706
114TP63_22573176_ChIP-Seq_HFKS_Human1.13083942
115IGF1R_20145208_ChIP-Seq_DFB_Human1.12971322
116IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12940532
117CBP_20019798_ChIP-Seq_JUKART_Human1.12940532
118ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12758737
119RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.12051523
120BCAT_22108803_ChIP-Seq_LS180_Human1.11985986
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11478879
122FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.11331849
123CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.10880056
124MYC_18940864_ChIP-ChIP_HL60_Human1.10088369
125RAD21_21589869_ChIP-Seq_MESCs_Mouse1.09848123
126RUNX2_22187159_ChIP-Seq_PCA_Human1.09829441
127SMRT_27268052_Chip-Seq_Bcells_Human1.09732085
128AR_19668381_ChIP-Seq_PC3_Human1.09531720
129CBX2_22325352_ChIP-Seq_293T-Rex_Human1.09527675
130TCF4_22108803_ChIP-Seq_LS180_Human1.09228741
131RBPJ_21746931_ChIP-Seq_IB4_Human1.08887042
132SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.08780369
133SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.08011225
134TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.06318480
135CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.05655658
136STAT4_19710469_ChIP-ChIP_TH1__Mouse1.05364261
137SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05225725
138VDR_23849224_ChIP-Seq_CD4+_Human1.05176815
139YY1_22570637_ChIP-Seq_MALME-3M_Human1.04235492
140TCF4_23295773_ChIP-Seq_U87_Human1.04002562
141TAL1_26923725_Chip-Seq_HPCs_Mouse1.03439351
142LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.03234406
143OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03228921
144POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.02397466
145MYC_18555785_ChIP-Seq_MESCs_Mouse1.02392320
146NFYB_21822215_ChIP-Seq_K562_Human1.01734760
147KLF5_25053715_ChIP-Seq_YYC3_Human1.01638901
148EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01558308
149CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.01531866
150FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01423032
151FOXA1_27270436_Chip-Seq_PROSTATE_Human1.01422031
152FOXA1_25329375_ChIP-Seq_VCAP_Human1.01422031
153SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.01287219
154REST_21632747_ChIP-Seq_MESCs_Mouse1.01109541
155FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.00935831
156E2F1_17053090_ChIP-ChIP_MCF-7_Human1.00931816
157ERG_20517297_ChIP-Seq_VCAP_Human1.00875909
158NFYA_21822215_ChIP-Seq_K562_Human1.00858537
159FOXA1_25552417_ChIP-Seq_VCAP_Human1.00008585
160MYC_19829295_ChIP-Seq_ESCs_Human0.98828874
161CEBPB_22108803_ChIP-Seq_LS180_Human0.96543608
162LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96526542
163P300_19829295_ChIP-Seq_ESCs_Human0.96289792
164SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.96285781
165GATA6_21074721_ChIP-Seq_CACO-2_Human0.95727245
166CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95542556
167ELF1_20517297_ChIP-Seq_JURKAT_Human0.94999030
168HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.94218000
169GATA3_21867929_ChIP-Seq_CD8_Mouse0.93891867
170TP63_19390658_ChIP-ChIP_HaCaT_Human0.93445322
171SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.92535205
172TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92096545
173ELK1_19687146_ChIP-ChIP_HELA_Human0.91980659
174CDX2_20551321_ChIP-Seq_CACO-2_Human0.91756236
175GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90287052
176TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90263948
177CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.90235149
178HOXB4_20404135_ChIP-ChIP_EML_Mouse0.88094187
179JARID2_20075857_ChIP-Seq_MESCs_Mouse0.87913807
180SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.87549644
181NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.87242201
182MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87210354
183CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.86670998
184ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85384469
185ER_23166858_ChIP-Seq_MCF-7_Human0.83911705
186TTF2_22483619_ChIP-Seq_HELA_Human0.83854887

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.86799822
2MP0008875_abnormal_xenobiotic_pharmacok6.25340142
3MP0006292_abnormal_olfactory_placode4.66777204
4MP0001188_hyperpigmentation3.89591705
5MP0009379_abnormal_foot_pigmentation3.63421802
6MP0004043_abnormal_pH_regulation3.45364093
7MP0004381_abnormal_hair_follicle3.30736020
8MP0004133_heterotaxia3.28720868
9MP0003880_abnormal_central_pattern3.25138961
10MP0005409_darkened_coat_color2.81909680
11MP0005623_abnormal_meninges_morphology2.68046523
12MP0005377_hearing/vestibular/ear_phenot2.59127437
13MP0003878_abnormal_ear_physiology2.59127437
14MP0003183_abnormal_peptide_metabolism2.58554960
15MP0000015_abnormal_ear_pigmentation2.40019521
16MP0002009_preneoplasia2.36747092
17MP0000566_synostosis2.30453678
18MP0005174_abnormal_tail_pigmentation2.30184326
19MP0000383_abnormal_hair_follicle2.10911714
20MP0002638_abnormal_pupillary_reflex2.09150956
21MP0003724_increased_susceptibility_to2.02830413
22MP0010030_abnormal_orbit_morphology2.01804264
23MP0009780_abnormal_chondrocyte_physiolo2.01732042
24MP0004019_abnormal_vitamin_homeostasis1.93766948
25MP0002277_abnormal_respiratory_mucosa1.92263007
26MP0005075_abnormal_melanosome_morpholog1.90173181
27MP0003938_abnormal_ear_development1.89922902
28MP0000372_irregular_coat_pigmentation1.89610677
29MP0002139_abnormal_hepatobiliary_system1.83393545
30MP0001986_abnormal_taste_sensitivity1.75886081
31MP0005171_absent_coat_pigmentation1.69894038
32MP0010678_abnormal_skin_adnexa1.69140393
33MP0002938_white_spotting1.68919057
34MP0002095_abnormal_skin_pigmentation1.68149565
35MP0002249_abnormal_larynx_morphology1.67840103
36MP0000049_abnormal_middle_ear1.62927049
37MP0003763_abnormal_thymus_physiology1.61412667
38MP0009785_altered_susceptibility_to1.57786435
39MP0002734_abnormal_mechanical_nocicepti1.55997106
40MP0005310_abnormal_salivary_gland1.55361901
41MP0009046_muscle_twitch1.52983708
42MP0002282_abnormal_trachea_morphology1.50680487
43MP0002735_abnormal_chemical_nociception1.50078277
44MP0005083_abnormal_biliary_tract1.49272852
45MP0008260_abnormal_autophagy1.49110816
46MP0008789_abnormal_olfactory_epithelium1.47159334
47MP0002876_abnormal_thyroid_physiology1.46415621
48MP0002928_abnormal_bile_duct1.44771090
49MP0002909_abnormal_adrenal_gland1.43296943
50MP0005084_abnormal_gallbladder_morpholo1.42157112
51MP0002148_abnormal_hypersensitivity_rea1.39250191
52MP0005671_abnormal_response_to1.38304834
53MP0002822_catalepsy1.35864116
54MP0008058_abnormal_DNA_repair1.34773007
55MP0005551_abnormal_eye_electrophysiolog1.32462583
56MP0001293_anophthalmia1.31871066
57MP0002177_abnormal_outer_ear1.30242652
58MP0002132_abnormal_respiratory_system1.29395060
59MP0003786_premature_aging1.27279835
60MP0002751_abnormal_autonomic_nervous1.26939970
61MP0000681_abnormal_thyroid_gland1.26298989
62MP0000026_abnormal_inner_ear1.25352056
63MP0005394_taste/olfaction_phenotype1.25349632
64MP0005499_abnormal_olfactory_system1.25349632
65MP0002160_abnormal_reproductive_system1.24584930
66MP0003718_maternal_effect1.24346110
67MP0002233_abnormal_nose_morphology1.23251569
68MP0009333_abnormal_splenocyte_physiolog1.21416521
69MP0003315_abnormal_perineum_morphology1.19102104
70MP0001919_abnormal_reproductive_system1.18399238
71MP0006276_abnormal_autonomic_nervous1.17756834
72MP0008007_abnormal_cellular_replicative1.17756507
73MP0002168_other_aberrant_phenotype1.15767956
74MP0005000_abnormal_immune_tolerance1.11018162
75MP0002102_abnormal_ear_morphology1.09673178
76MP0001835_abnormal_antigen_presentation1.09273432
77MP0009250_abnormal_appendicular_skeleto1.06968918
78MP0001984_abnormal_olfaction1.06009366
79MP0005395_other_phenotype1.04096781
80MP0000631_abnormal_neuroendocrine_gland1.03237699
81MP0000490_abnormal_crypts_of0.96058932
82MP0004142_abnormal_muscle_tone0.94185796
83MP0002163_abnormal_gland_morphology0.94074487
84MP0005389_reproductive_system_phenotype0.91983973
85MP0008995_early_reproductive_senescence0.91197101
86MP0005025_abnormal_response_to0.91165817
87MP0005195_abnormal_posterior_eye0.90478405
88MP0001879_abnormal_lymphatic_vessel0.89655706
89MP0001819_abnormal_immune_cell0.86504159
90MP0003656_abnormal_erythrocyte_physiolo0.86149957
91MP0002420_abnormal_adaptive_immunity0.85755133
92MP0003806_abnormal_nucleotide_metabolis0.85430973
93MP0002723_abnormal_immune_serum0.85087281
94MP0004742_abnormal_vestibular_system0.85059171
95MP0004782_abnormal_surfactant_physiolog0.84594640
96MP0002210_abnormal_sex_determination0.83408225
97MP0005248_abnormal_Harderian_gland0.83069879
98MP0001486_abnormal_startle_reflex0.82587842
99MP0001186_pigmentation_phenotype0.82366902
100MP0001968_abnormal_touch/_nociception0.82267171
101MP0005187_abnormal_penis_morphology0.82223751
102MP0001970_abnormal_pain_threshold0.82005059
103MP0001765_abnormal_ion_homeostasis0.81808927
104MP0000613_abnormal_salivary_gland0.81373270
105MP0001346_abnormal_lacrimal_gland0.81175631
106MP0005645_abnormal_hypothalamus_physiol0.80923817
107MP0005391_vision/eye_phenotype0.80531232
108MP0001963_abnormal_hearing_physiology0.80158333
109MP0002452_abnormal_antigen_presenting0.79286056
110MP0005408_hypopigmentation0.78068154
111MP0001790_abnormal_immune_system0.77896965
112MP0005387_immune_system_phenotype0.77896965
113MP0000955_abnormal_spinal_cord0.77755721
114MP0003436_decreased_susceptibility_to0.77710615
115MP0009745_abnormal_behavioral_response0.77502253
116MP0001800_abnormal_humoral_immune0.77319169
117MP0003861_abnormal_nervous_system0.76941249
118MP0001299_abnormal_eye_distance/0.76624168
119MP0000678_abnormal_parathyroid_gland0.76135749
120MP0002572_abnormal_emotion/affect_behav0.75837270
121MP0001905_abnormal_dopamine_level0.73057288
122MP0000858_altered_metastatic_potential0.72837894
123MP0001529_abnormal_vocalization0.72686483
124MP0002116_abnormal_craniofacial_bone0.72239426
125MP0002419_abnormal_innate_immunity0.72234255
126MP0001348_abnormal_lacrimal_gland0.72042533
127MP0001485_abnormal_pinna_reflex0.71807290
128MP0002653_abnormal_ependyma_morphology0.69956244
129MP0005410_abnormal_fertilization0.69513672
130MP0005379_endocrine/exocrine_gland_phen0.67629542
131MP0002557_abnormal_social/conspecific_i0.66642639
132MP0002161_abnormal_fertility/fecundity0.66021401
133MP0005670_abnormal_white_adipose0.65914281
134MP0006082_CNS_inflammation0.65386456
135MP0002405_respiratory_system_inflammati0.65233948
136MP0002234_abnormal_pharynx_morphology0.65068097
137MP0001119_abnormal_female_reproductive0.64634463
138MP0003698_abnormal_male_reproductive0.64420726
139MP0005253_abnormal_eye_physiology0.63147293
140MP0002752_abnormal_somatic_nervous0.62546384
141MP0002272_abnormal_nervous_system0.62546332
142MP0002152_abnormal_brain_morphology0.61819430
143MP0003011_delayed_dark_adaptation0.61726036
144MP0002075_abnormal_coat/hair_pigmentati0.61482939
145MP0002229_neurodegeneration0.60652393
146MP0009643_abnormal_urine_homeostasis0.60375583
147MP0001286_abnormal_eye_development0.60278416
148MP0005647_abnormal_sex_gland0.60092652
149MP0000778_abnormal_nervous_system0.58949609
150MP0003937_abnormal_limbs/digits/tail_de0.58691822
151MP0001929_abnormal_gametogenesis0.58505836
152MP0001324_abnormal_eye_pigmentation0.58476783
153MP0002064_seizures0.58383331
154MP0002882_abnormal_neuron_morphology0.58153964
155MP0000716_abnormal_immune_system0.58002919
156MP0008932_abnormal_embryonic_tissue0.56855258
157MP0000569_abnormal_digit_pigmentation0.55457422
158MP0005636_abnormal_mineral_homeostasis0.54801321
159MP0003942_abnormal_urinary_system0.54691327
160MP0002138_abnormal_hepatobiliary_system0.54428675
161MP0000653_abnormal_sex_gland0.53441762
162MP0001145_abnormal_male_reproductive0.50120353

Predicted human phenotypes

RankGene SetZ-score
1Nasal polyposis (HP:0100582)6.47833628
2Abnormal ciliary motility (HP:0012262)5.37846451
3Abnormality of the nasal mucosa (HP:0000433)5.34409278
4Abnormal respiratory motile cilium physiology (HP:0012261)4.85196493
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.59748290
6Abnormal respiratory epithelium morphology (HP:0012253)4.26715138
7Abnormal respiratory motile cilium morphology (HP:0005938)4.26715138
8Infertility (HP:0000789)4.24711192
9Occipital encephalocele (HP:0002085)4.08898068
10Type I transferrin isoform profile (HP:0003642)4.02989355
11Bronchitis (HP:0012387)3.95500260
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.77441172
13Absent/shortened dynein arms (HP:0200106)3.77441172
14Chronic sinusitis (HP:0011109)3.65300781
15Reduced antithrombin III activity (HP:0001976)3.61277500
16Chronic hepatic failure (HP:0100626)3.56965591
17Recurrent otitis media (HP:0000403)3.51153856
18Male infertility (HP:0003251)3.40348858
19Rhinitis (HP:0012384)3.39484283
20Abnormal sex determination (HP:0012244)3.31598105
21Sex reversal (HP:0012245)3.31598105
22Cystic liver disease (HP:0006706)3.25507097
23True hermaphroditism (HP:0010459)3.18893896
24Atelectasis (HP:0100750)3.13893386
25Nephronophthisis (HP:0000090)3.11110253
26Amelogenesis imperfecta (HP:0000705)3.03799979
27Supernumerary spleens (HP:0009799)2.96967926
28Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.89440237
29Nonprogressive disorder (HP:0003680)2.78168635
30Postaxial foot polydactyly (HP:0001830)2.76640340
31Median cleft lip (HP:0000161)2.74589028
32Abnormality of the phalanges of the hallux (HP:0010057)2.67776302
33Hyperactive renin-angiotensin system (HP:0000841)2.64303244
343-Methylglutaconic aciduria (HP:0003535)2.59320220
35Optic disc pallor (HP:0000543)2.56832106
36Abnormality of the axillary hair (HP:0100134)2.55542534
37Abnormality of secondary sexual hair (HP:0009888)2.55542534
38Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.55537337
39Hypoplasia of the fovea (HP:0007750)2.53950092
40Aplasia/Hypoplasia of the fovea (HP:0008060)2.53950092
41Chronic otitis media (HP:0000389)2.53573834
42Chronic obstructive pulmonary disease (HP:0006510)2.50502021
43Obstructive lung disease (HP:0006536)2.50502021
44Chromosomal breakage induced by crosslinking agents (HP:0003221)2.50066095
45Abnormality of dental color (HP:0011073)2.49153022
46Aplasia/Hypoplasia of the sacrum (HP:0008517)2.48827402
47Abnormality of cells of the erythroid lineage (HP:0012130)2.45043494
48Reticulocytopenia (HP:0001896)2.42449890
49Abnormal number of erythroid precursors (HP:0012131)2.42037502
50Dry hair (HP:0011359)2.41793218
51Optic nerve hypoplasia (HP:0000609)2.38634841
52Anencephaly (HP:0002323)2.37484847
53Abnormality of the renal medulla (HP:0100957)2.35710138
54Pancreatic fibrosis (HP:0100732)2.33023079
55Congenital hepatic fibrosis (HP:0002612)2.32786377
56Triphalangeal thumb (HP:0001199)2.31716984
57Bronchiectasis (HP:0002110)2.31072714
58Congenital primary aphakia (HP:0007707)2.27724302
59Hypothermia (HP:0002045)2.25164650
60Gait imbalance (HP:0002141)2.25064569
61Abnormal protein glycosylation (HP:0012346)2.23349213
62Abnormal glycosylation (HP:0012345)2.23349213
63Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23349213
64Abnormal protein N-linked glycosylation (HP:0012347)2.23349213
65Meckel diverticulum (HP:0002245)2.19299425
66Increased IgM level (HP:0003496)2.17874855
67Septo-optic dysplasia (HP:0100842)2.16660096
68Renal Fanconi syndrome (HP:0001994)2.14178536
69Medial flaring of the eyebrow (HP:0010747)2.11256185
70Tubular atrophy (HP:0000092)2.10670422
71Decreased circulating renin level (HP:0003351)2.10583147
72Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.09783033
73Abnormality of the ileum (HP:0001549)2.08858514
74Absent septum pellucidum (HP:0001331)2.07640474
75Concave nail (HP:0001598)2.07634561
76Abnormality of the fovea (HP:0000493)2.06483437
77Recurrent sinusitis (HP:0011108)2.06025872
78Abnormality of the preputium (HP:0100587)2.05947317
79Aplasia/Hypoplasia of the uvula (HP:0010293)2.05808021
80Male pseudohermaphroditism (HP:0000037)2.05674037
81Pancreatic cysts (HP:0001737)2.04405252
82Thyroid-stimulating hormone excess (HP:0002925)2.02577620
83Nephrogenic diabetes insipidus (HP:0009806)2.00458362
84Sclerocornea (HP:0000647)1.98406808
85Chromsome breakage (HP:0040012)1.98043776
86Preaxial hand polydactyly (HP:0001177)1.98030191
87Macrocytic anemia (HP:0001972)1.96647281
88Absent rod-and cone-mediated responses on ERG (HP:0007688)1.96313375
89Abnormality of the septum pellucidum (HP:0007375)1.96228713
90Recurrent cutaneous fungal infections (HP:0011370)1.94988494
91Chronic mucocutaneous candidiasis (HP:0002728)1.94988494
92Attenuation of retinal blood vessels (HP:0007843)1.94442564
93Focal motor seizures (HP:0011153)1.94077831
94Clubbing of toes (HP:0100760)1.93035508
95Hypoplasia of the radius (HP:0002984)1.92882521
96Abnormal hemoglobin (HP:0011902)1.91562366
97Meningitis (HP:0001287)1.91159227
98Absent thumb (HP:0009777)1.89934357
99Capillary hemangiomas (HP:0005306)1.89341383
100Cheilitis (HP:0100825)1.87974112
101Postaxial hand polydactyly (HP:0001162)1.86434642
102Short tibia (HP:0005736)1.86360268
103Bell-shaped thorax (HP:0001591)1.86218838
104Testicular atrophy (HP:0000029)1.85701946
105Furrowed tongue (HP:0000221)1.85421958
106Abnormal biliary tract physiology (HP:0012439)1.85228490
107Bile duct proliferation (HP:0001408)1.85228490
108Aplasia/Hypoplasia of the spleen (HP:0010451)1.83847287
109Abnormal lung lobation (HP:0002101)1.83361660
110Aplasia/Hypoplasia of the tibia (HP:0005772)1.83246890
111Exertional dyspnea (HP:0002875)1.82486111
112Adrenal hypoplasia (HP:0000835)1.81411047
113Stomatitis (HP:0010280)1.81135869
114Aganglionic megacolon (HP:0002251)1.80509907
115Tubulointerstitial nephritis (HP:0001970)1.80192363
116Anhidrosis (HP:0000970)1.80077625
117Aplasia/Hypoplasia of the tongue (HP:0010295)1.78815694
118Increased hepatocellular lipid droplets (HP:0006565)1.77955530
119Oculomotor apraxia (HP:0000657)1.77052421
120Metabolic alkalosis (HP:0200114)1.76668106
121Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.75939543
122Cone-rod dystrophy (HP:0000548)1.75384893
123Vacuolated lymphocytes (HP:0001922)1.75312750
124Parakeratosis (HP:0001036)1.74931187
125Asplenia (HP:0001746)1.74881840
126Nephropathy (HP:0000112)1.72777069
127Abnormality of midbrain morphology (HP:0002418)1.72606187
128Molar tooth sign on MRI (HP:0002419)1.72606187
129Mitochondrial inheritance (HP:0001427)1.72178008
130Abnormality of renal resorption (HP:0011038)1.71093897
131Chronic bronchitis (HP:0004469)1.70875187
132Genital tract atresia (HP:0001827)1.68599422
133Poor coordination (HP:0002370)1.67781099
134Vaginal atresia (HP:0000148)1.63658304
135Abnormality of dentin (HP:0010299)1.58503809
136Stage 5 chronic kidney disease (HP:0003774)1.54090979
137Tubulointerstitial abnormality (HP:0001969)1.48189889
138Renal salt wasting (HP:0000127)1.48027937
139Recurrent bronchitis (HP:0002837)1.47735619
140Polydipsia (HP:0001959)1.47692965
141Abnormal drinking behavior (HP:0030082)1.47692965
142Hyperkalemia (HP:0002153)1.45286241
143Hyperaldosteronism (HP:0000859)1.43906729
144Absent frontal sinuses (HP:0002688)1.42354410
145Abnormality of the dental pulp (HP:0006479)1.36072931
146Abnormality of renin-angiotensin system (HP:0000847)1.30150631
147Retinitis pigmentosa (HP:0000510)1.30134100
148Bony spicule pigmentary retinopathy (HP:0007737)1.20493765
149Hand muscle atrophy (HP:0009130)1.18375562
150Chorioretinal coloboma (HP:0000567)1.18288650
151Prominent nasal bridge (HP:0000426)1.16612269
152Abnormality of chloride homeostasis (HP:0011422)1.16446888
153Short thorax (HP:0010306)1.14204384
154Abnormal rod and cone electroretinograms (HP:0008323)1.13541716
155Abnormality of permanent molar morphology (HP:0011071)1.12526972
156Abnormality of the dental root (HP:0006486)1.12526972
157Taurodontia (HP:0000679)1.12526972
158Narrow forehead (HP:0000341)1.12140945
159Glucose intolerance (HP:0000833)1.11605522
160Multicystic kidney dysplasia (HP:0000003)1.11392367
161Aplasia/Hypoplasia of the lens (HP:0008063)1.10272159
162Absent speech (HP:0001344)1.08528516
163Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.08524500
164Decreased central vision (HP:0007663)1.08382934
165Broad foot (HP:0001769)1.07819913
166Abnormality of the renal cortex (HP:0011035)1.07074166
167Short nail (HP:0001799)1.06912466
168Optic nerve coloboma (HP:0000588)1.05361801
169Tubulointerstitial fibrosis (HP:0005576)1.04206366
170Left ventricular hypertrophy (HP:0001712)1.03799708
171Broad distal phalanx of finger (HP:0009836)1.03183086
172Abnormality of molar morphology (HP:0011070)1.00961080
173Abnormality of molar (HP:0011077)1.00961080

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.28107727
2NME23.67872899
3EPHA23.57065992
4WNK33.29112769
5MKNK23.19697720
6PRKD23.03101103
7FRK2.97761429
8CLK12.72583967
9NLK2.60604099
10TLK12.60409139
11MUSK2.41653573
12MAPKAPK32.30560256
13TNIK2.29820900
14IRAK32.26999820
15IRAK42.23947337
16EEF2K2.17907544
17TXK2.08609397
18STK382.06621416
19MAPK152.05527145
20PRPF4B2.03756491
21YES12.02319759
22MKNK12.02135160
23SRPK11.91749997
24NME11.91068916
25AKT31.87167920
26BCR1.82001843
27PTK2B1.75313307
28MST41.63982424
29TTK1.58901311
30IRAK21.58176407
31IRAK11.49133142
32EIF2AK31.47942757
33VRK11.47439735
34GRK71.47251948
35STK161.47076038
36PNCK1.40109876
37PIM21.35366388
38ADRBK21.33369889
39EIF2AK21.26856036
40MAP3K41.23223100
41MAP3K141.21494922
42NEK61.21451223
43BMPR21.18579041
44TEC1.18165876
45MAP2K71.17332445
46BLK1.16065498
47STK38L1.14505213
48MAP3K71.14110410
49TSSK61.10689156
50BRAF1.08685533
51EPHA41.07102320
52PRKD31.01798550
53HIPK21.01624262
54TRPM70.99943793
55EPHA30.99848866
56FGR0.98243498
57GRK50.94733061
58CDK30.93189608
59LRRK20.91062055
60MAP3K20.90578862
61PIM10.89497418
62DYRK30.88770042
63EPHB10.86738498
64IKBKE0.86280418
65TESK10.85774263
66ZAP700.84837943
67MARK20.83671266
68PRKCZ0.83643586
69IKBKB0.83464986
70MAPK130.82325854
71GRK10.81717762
72FER0.79429156
73UHMK10.77243143
74TNK20.75616146
75CSNK1G10.72912065
76PINK10.72384582
77SGK20.70128888
78DYRK20.67145756
79ERBB20.66313406
80GRK60.63769167
81INSRR0.63665596
82MAP3K120.61117254
83STK110.59025383
84TGFBR20.58054422
85BTK0.57357226
86MOS0.56969732
87LYN0.56883612
88DYRK1A0.56229062
89ZAK0.55480252
90SMG10.54733744
91AURKA0.54306982
92CSK0.53451128
93PIK3CA0.52814901
94RIPK40.51950975
95PBK0.51941240
96MET0.51659468
97STK100.49551708
98MAP3K30.48858157
99RPS6KA50.48060893
100OXSR10.47880734
101MAP4K20.47611492
102PLK40.47130143
103SYK0.45059857
104PLK10.43708178
105CDK120.43225367
106FES0.43151345
107PRKG20.41909055
108CAMK2B0.40625303
109PRKACA0.40621355
110CSNK2A10.39411236
111MAPKAPK50.38487611
112MAP4K10.38462985
113ARAF0.37958828
114RPS6KL10.37727669
115RPS6KC10.37727669
116CAMK2G0.37545929
117PRKCI0.37367687
118MAP2K40.36637544
119CHEK20.36157459
120NTRK30.36073397
121RPS6KA60.35716504
122LCK0.35427566
123AKT20.34390904
124PRKCA0.34369552
125BUB10.34126790
126PAK10.33715083
127TAOK20.33135469
128SGK2230.33113327
129SGK4940.33113327
130DYRK1B0.33093685
131BCKDK0.31292181
132PRKCQ0.30847271
133WEE10.30786505
134TRIM280.30209302
135MST1R0.30036061
136ERBB30.29286047
137PRKG10.29073620
138PRKAA20.28841763
139CAMK2A0.28782015
140ADRBK10.28504268
141PRKCD0.27770941
142MAP2K60.27619323
143RPS6KA20.27524336
144SGK10.27265529
145MAPK120.26914060
146LIMK10.26873191
147STK390.26797970
148EIF2AK10.26694285
149CHUK0.26021094
150CDK190.24382184
151CDK70.23981996
152PASK0.23540614
153CAMKK20.21858178
154STK240.21565095
155CAMKK10.20929282
156PRKCH0.20816074
157IGF1R0.20549366
158MAP3K60.20402142
159RET0.20388657
160MINK10.19918380
161RPS6KB20.18898739
162SRC0.17982850
163FYN0.17801868
164PRKDC0.17125043
165ROCK20.16291717

Predicted pathways (KEGG)

RankGene SetZ-score
1Histidine metabolism_Homo sapiens_hsa003404.70036102
2Ribosome_Homo sapiens_hsa030104.20215358
3Phenylalanine metabolism_Homo sapiens_hsa003603.88598979
4Chemical carcinogenesis_Homo sapiens_hsa052043.80450769
5Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.57794479
6Tyrosine metabolism_Homo sapiens_hsa003503.14763623
7Graft-versus-host disease_Homo sapiens_hsa053322.58793219
8beta-Alanine metabolism_Homo sapiens_hsa004102.58459679
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.52425236
10Glycosaminoglycan degradation_Homo sapiens_hsa005312.49681179
11Homologous recombination_Homo sapiens_hsa034402.42700409
12Protein export_Homo sapiens_hsa030602.37270261
13Fanconi anemia pathway_Homo sapiens_hsa034602.33125877
14DNA replication_Homo sapiens_hsa030302.12037404
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.11387736
16RNA polymerase_Homo sapiens_hsa030202.02345934
17Basal transcription factors_Homo sapiens_hsa030221.96907568
18Arachidonic acid metabolism_Homo sapiens_hsa005901.85422376
19Allograft rejection_Homo sapiens_hsa053301.81159115
20Other glycan degradation_Homo sapiens_hsa005111.75429810
21Oxidative phosphorylation_Homo sapiens_hsa001901.70904630
22Spliceosome_Homo sapiens_hsa030401.70846012
23Caffeine metabolism_Homo sapiens_hsa002321.67188666
24Pyrimidine metabolism_Homo sapiens_hsa002401.64136680
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.60835484
26Nucleotide excision repair_Homo sapiens_hsa034201.56642780
27Ether lipid metabolism_Homo sapiens_hsa005651.56266793
28Primary immunodeficiency_Homo sapiens_hsa053401.52915059
29Base excision repair_Homo sapiens_hsa034101.51291105
30Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.51174166
31Butanoate metabolism_Homo sapiens_hsa006501.49452088
32Peroxisome_Homo sapiens_hsa041461.48360707
33Proteasome_Homo sapiens_hsa030501.45722860
34Autoimmune thyroid disease_Homo sapiens_hsa053201.44788007
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.44166206
36Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.43540172
37Asthma_Homo sapiens_hsa053101.40951908
38Phototransduction_Homo sapiens_hsa047441.40903626
39Thyroid cancer_Homo sapiens_hsa052161.40844780
40Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40831736
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.38745612
42Fatty acid degradation_Homo sapiens_hsa000711.36626382
43Huntingtons disease_Homo sapiens_hsa050161.36250420
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.35026748
45Mismatch repair_Homo sapiens_hsa034301.34457235
46ABC transporters_Homo sapiens_hsa020101.34011022
47Measles_Homo sapiens_hsa051621.33534015
48NF-kappa B signaling pathway_Homo sapiens_hsa040641.29560563
49Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28375794
50Salivary secretion_Homo sapiens_hsa049701.28180018
51SNARE interactions in vesicular transport_Homo sapiens_hsa041301.25786290
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.24683388
53Sphingolipid metabolism_Homo sapiens_hsa006001.24649315
54Purine metabolism_Homo sapiens_hsa002301.19306463
55Primary bile acid biosynthesis_Homo sapiens_hsa001201.19060008
56Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16584534
57Basal cell carcinoma_Homo sapiens_hsa052171.15645191
58Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.10973492
59Parkinsons disease_Homo sapiens_hsa050121.09938574
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.09205451
61Tight junction_Homo sapiens_hsa045301.05509912
62Hematopoietic cell lineage_Homo sapiens_hsa046401.04988764
63Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03336867
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02720410
65Propanoate metabolism_Homo sapiens_hsa006401.02684754
66RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.99824122
67Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.97477602
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.95935613
69Rheumatoid arthritis_Homo sapiens_hsa053230.91206985
70Herpes simplex infection_Homo sapiens_hsa051680.88347108
71Alzheimers disease_Homo sapiens_hsa050100.88069305
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.85880053
73Wnt signaling pathway_Homo sapiens_hsa043100.85195032
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.83791242
75Transcriptional misregulation in cancer_Homo sapiens_hsa052020.82248113
76Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.78740421
77Linoleic acid metabolism_Homo sapiens_hsa005910.78143693
78Regulation of autophagy_Homo sapiens_hsa041400.76930495
79Glycerolipid metabolism_Homo sapiens_hsa005610.76606196
80Tryptophan metabolism_Homo sapiens_hsa003800.76361682
81Antigen processing and presentation_Homo sapiens_hsa046120.75833352
82Type I diabetes mellitus_Homo sapiens_hsa049400.74812677
83Nicotine addiction_Homo sapiens_hsa050330.72711326
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72427179
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.70189453
86Leishmaniasis_Homo sapiens_hsa051400.69338349
87Malaria_Homo sapiens_hsa051440.69314649
88cAMP signaling pathway_Homo sapiens_hsa040240.69277695
89Calcium signaling pathway_Homo sapiens_hsa040200.68115339
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68058179
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67486290
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.66199013
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.64515022
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63979006
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62916658
96Arginine and proline metabolism_Homo sapiens_hsa003300.62701363
97Cardiac muscle contraction_Homo sapiens_hsa042600.62125739
98Pyruvate metabolism_Homo sapiens_hsa006200.61797704
99Acute myeloid leukemia_Homo sapiens_hsa052210.60564982
100Non-homologous end-joining_Homo sapiens_hsa034500.60157195
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.59572026
102Adherens junction_Homo sapiens_hsa045200.58346123
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.58318776
104Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58239961
105Selenocompound metabolism_Homo sapiens_hsa004500.58180568
106Hippo signaling pathway_Homo sapiens_hsa043900.57302838
107p53 signaling pathway_Homo sapiens_hsa041150.55704976
108Ovarian steroidogenesis_Homo sapiens_hsa049130.55510690
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55151010
110Steroid hormone biosynthesis_Homo sapiens_hsa001400.54756670
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52327256
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52081403
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50975790
114RNA degradation_Homo sapiens_hsa030180.50666577
115Notch signaling pathway_Homo sapiens_hsa043300.50481668
116Epstein-Barr virus infection_Homo sapiens_hsa051690.49992360
117Olfactory transduction_Homo sapiens_hsa047400.48513557
118Starch and sucrose metabolism_Homo sapiens_hsa005000.47951741
119Prostate cancer_Homo sapiens_hsa052150.47950712
120Toll-like receptor signaling pathway_Homo sapiens_hsa046200.47095397
121Circadian rhythm_Homo sapiens_hsa047100.46440899
122One carbon pool by folate_Homo sapiens_hsa006700.45216960
123Melanogenesis_Homo sapiens_hsa049160.44006453
124Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.43078388
125Taste transduction_Homo sapiens_hsa047420.42423426
126N-Glycan biosynthesis_Homo sapiens_hsa005100.42104217
127Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41691459
128Hedgehog signaling pathway_Homo sapiens_hsa043400.40295228
129Influenza A_Homo sapiens_hsa051640.39318529
130Cell cycle_Homo sapiens_hsa041100.38745780
131Maturity onset diabetes of the young_Homo sapiens_hsa049500.38278715
132Axon guidance_Homo sapiens_hsa043600.37880540
133Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37612164
134Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.36876186
135Choline metabolism in cancer_Homo sapiens_hsa052310.36714997
136Pertussis_Homo sapiens_hsa051330.36496705
137Cocaine addiction_Homo sapiens_hsa050300.36495640
138Steroid biosynthesis_Homo sapiens_hsa001000.35889908
139PPAR signaling pathway_Homo sapiens_hsa033200.35866657
140Serotonergic synapse_Homo sapiens_hsa047260.35828481
141Mineral absorption_Homo sapiens_hsa049780.35530781
142Collecting duct acid secretion_Homo sapiens_hsa049660.35453943
143Glutathione metabolism_Homo sapiens_hsa004800.35385653
144Metabolic pathways_Homo sapiens_hsa011000.34670138
145Morphine addiction_Homo sapiens_hsa050320.34485780
146Folate biosynthesis_Homo sapiens_hsa007900.34019362
147Drug metabolism - other enzymes_Homo sapiens_hsa009830.33201016
148T cell receptor signaling pathway_Homo sapiens_hsa046600.31825022
149Legionellosis_Homo sapiens_hsa051340.30851040
150Salmonella infection_Homo sapiens_hsa051320.30348102
151Fatty acid biosynthesis_Homo sapiens_hsa000610.29669677
152African trypanosomiasis_Homo sapiens_hsa051430.28533805
153Vitamin digestion and absorption_Homo sapiens_hsa049770.28408803
154Inositol phosphate metabolism_Homo sapiens_hsa005620.28369215
155Retinol metabolism_Homo sapiens_hsa008300.28059491
156Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.26670237
157Synaptic vesicle cycle_Homo sapiens_hsa047210.23251146
158Sulfur relay system_Homo sapiens_hsa041220.22105370
159Fat digestion and absorption_Homo sapiens_hsa049750.21679439
160Nitrogen metabolism_Homo sapiens_hsa009100.19290404
161Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.18552139
162Oxytocin signaling pathway_Homo sapiens_hsa049210.17022423
163Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.16249944
164Fatty acid metabolism_Homo sapiens_hsa012120.15636411
165Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.15355067
166Gastric acid secretion_Homo sapiens_hsa049710.14937485
167Leukocyte transendothelial migration_Homo sapiens_hsa046700.14792135

Most similar genes based on co-expression Upload to Enrichr

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