CFDP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)4.78991460
2mitotic metaphase plate congression (GO:0007080)4.70820240
3nucleobase biosynthetic process (GO:0046112)4.70108892
4formation of translation preinitiation complex (GO:0001731)4.67026628
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.55601491
6maturation of SSU-rRNA (GO:0030490)4.35363028
7ribosome assembly (GO:0042255)4.25687777
8DNA replication checkpoint (GO:0000076)4.25223465
9DNA strand elongation involved in DNA replication (GO:0006271)4.19376083
10DNA replication initiation (GO:0006270)4.19037985
11ribosome biogenesis (GO:0042254)4.15931905
12ribosomal small subunit assembly (GO:0000028)4.08318308
13metaphase plate congression (GO:0051310)4.02554692
14proteasome assembly (GO:0043248)4.02270122
15DNA strand elongation (GO:0022616)3.97260574
16protein localization to kinetochore (GO:0034501)3.97159252
17ribosomal large subunit biogenesis (GO:0042273)3.95365153
18ATP synthesis coupled proton transport (GO:0015986)3.93417066
19energy coupled proton transport, down electrochemical gradient (GO:0015985)3.93417066
20ribonucleoprotein complex biogenesis (GO:0022613)3.91790635
21telomere maintenance via semi-conservative replication (GO:0032201)3.87537902
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.78305544
23CENP-A containing nucleosome assembly (GO:0034080)3.76932277
24positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.76051474
25anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.75810701
26chromatin remodeling at centromere (GO:0031055)3.74867669
27spliceosomal snRNP assembly (GO:0000387)3.73908103
28IMP biosynthetic process (GO:0006188)3.73465691
29cullin deneddylation (GO:0010388)3.73254670
30regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.72158215
31pyrimidine nucleobase catabolic process (GO:0006208)3.70281902
32kinetochore organization (GO:0051383)3.68567651
33nuclear pore organization (GO:0006999)3.61677721
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.61085992
35kinetochore assembly (GO:0051382)3.56828608
36mitotic nuclear envelope disassembly (GO:0007077)3.56381127
37rRNA processing (GO:0006364)3.56109879
38telomere maintenance via recombination (GO:0000722)3.55414239
39transcription elongation from RNA polymerase III promoter (GO:0006385)3.55387781
40termination of RNA polymerase III transcription (GO:0006386)3.55387781
41presynaptic membrane assembly (GO:0097105)3.54706614
42DNA unwinding involved in DNA replication (GO:0006268)3.54278287
437-methylguanosine mRNA capping (GO:0006370)3.53948515
44establishment of chromosome localization (GO:0051303)3.52656060
45DNA replication-dependent nucleosome organization (GO:0034723)3.49980881
46DNA replication-dependent nucleosome assembly (GO:0006335)3.49980881
47RNA capping (GO:0036260)3.48155249
487-methylguanosine RNA capping (GO:0009452)3.48155249
49protein deneddylation (GO:0000338)3.47546469
50ribosomal small subunit biogenesis (GO:0042274)3.43660074
51rRNA metabolic process (GO:0016072)3.43583776
52negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.43272208
53negative regulation of ligase activity (GO:0051352)3.43272208
54mitotic recombination (GO:0006312)3.42903515
55DNA replication-independent nucleosome organization (GO:0034724)3.40475827
56DNA replication-independent nucleosome assembly (GO:0006336)3.40475827
57transcription-coupled nucleotide-excision repair (GO:0006283)3.39285981
58rRNA modification (GO:0000154)3.37953535
59transcription elongation from RNA polymerase I promoter (GO:0006362)3.37902318
60termination of RNA polymerase I transcription (GO:0006363)3.36703999
61positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.36257552
62establishment of integrated proviral latency (GO:0075713)3.35690130
63translational initiation (GO:0006413)3.34606090
64translational termination (GO:0006415)3.32960928
65chaperone-mediated protein transport (GO:0072321)3.32510663
66nonmotile primary cilium assembly (GO:0035058)3.31594532
67regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.31424196
68telomere maintenance via telomere lengthening (GO:0010833)3.30834976
69viral transcription (GO:0019083)3.30162396
70intraciliary transport (GO:0042073)3.29994129
71protein complex biogenesis (GO:0070271)3.29639841
72maturation of 5.8S rRNA (GO:0000460)3.28892173
73transcription from RNA polymerase I promoter (GO:0006360)3.28544401
74nuclear envelope disassembly (GO:0051081)3.28383930
75membrane disassembly (GO:0030397)3.28383930
76protein localization to chromosome, centromeric region (GO:0071459)3.27118647
77mitotic sister chromatid segregation (GO:0000070)3.26866403
78G1/S transition of mitotic cell cycle (GO:0000082)3.26505253
79cell cycle G1/S phase transition (GO:0044843)3.26505253
80nuclear pore complex assembly (GO:0051292)3.24561005
81respiratory electron transport chain (GO:0022904)3.23256347
82histone exchange (GO:0043486)3.22705704
83spliceosomal complex assembly (GO:0000245)3.21918370
84presynaptic membrane organization (GO:0097090)3.21491485
85nucleotide-excision repair, DNA gap filling (GO:0006297)3.20676348
86epithelial cilium movement (GO:0003351)3.20198757
87DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.19788478
88electron transport chain (GO:0022900)3.19261152
89establishment of protein localization to mitochondrial membrane (GO:0090151)3.18791690
90folic acid-containing compound biosynthetic process (GO:0009396)3.17883003
91spindle checkpoint (GO:0031577)3.17437818
92signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.15740418
93intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.15740418
94positive regulation of ligase activity (GO:0051351)3.14905221
95DNA deamination (GO:0045006)3.14607420
96signal transduction involved in DNA damage checkpoint (GO:0072422)3.14351262
97signal transduction involved in DNA integrity checkpoint (GO:0072401)3.14351262
98signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.14305822
99signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.14305822
100signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.14305822
101pseudouridine synthesis (GO:0001522)3.13321475
102viral mRNA export from host cell nucleus (GO:0046784)3.12797346
103negative regulation of mitotic sister chromatid separation (GO:2000816)3.12733724
104negative regulation of mitotic sister chromatid segregation (GO:0033048)3.12733724
105negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.12733724
106negative regulation of sister chromatid segregation (GO:0033046)3.12733724
107cellular component biogenesis (GO:0044085)3.12705891
108negative regulation of chromosome segregation (GO:0051985)3.12267548
109translational elongation (GO:0006414)3.10992947
110signal transduction involved in cell cycle checkpoint (GO:0072395)3.09779373
111regulation of spindle organization (GO:0090224)3.09199333
112regulation of centrosome cycle (GO:0046605)3.09195161
113mitotic spindle assembly checkpoint (GO:0007094)3.08924913
114regulation of cellular amino acid metabolic process (GO:0006521)3.08611417
115mitochondrial respiratory chain complex assembly (GO:0033108)3.07325424
116epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.05703934
117nucleobase catabolic process (GO:0046113)3.00484525
118behavioral response to nicotine (GO:0035095)2.98780581
119mitochondrial respiratory chain complex I assembly (GO:0032981)2.97464968
120NADH dehydrogenase complex assembly (GO:0010257)2.97464968
121mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.97464968
122DNA damage response, detection of DNA damage (GO:0042769)2.97219169
123cotranslational protein targeting to membrane (GO:0006613)2.92329050
124postsynaptic membrane organization (GO:0001941)2.91208313
125protein neddylation (GO:0045116)2.90701647
126SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.88878523
127limb bud formation (GO:0060174)2.86590090
128protein targeting to ER (GO:0045047)2.85653195
129cilium movement (GO:0003341)2.75893831
130establishment of protein localization to endoplasmic reticulum (GO:0072599)2.75801339
131protein localization to endoplasmic reticulum (GO:0070972)2.67615663
132regulation of cilium movement (GO:0003352)2.63142161
133negative regulation of DNA-dependent DNA replication (GO:2000104)2.62857600
134sequestering of actin monomers (GO:0042989)2.61782765
135retinal ganglion cell axon guidance (GO:0031290)2.61454669
136protein-cofactor linkage (GO:0018065)2.60250547
137regulation of mitochondrial translation (GO:0070129)2.56094305
138kidney morphogenesis (GO:0060993)2.54098735
139neuron cell-cell adhesion (GO:0007158)2.53359598
140axonemal dynein complex assembly (GO:0070286)2.48370731
141otic vesicle formation (GO:0030916)2.46088645
142nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.45805873
143nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.41532242
144neuron recognition (GO:0008038)2.41490329
145establishment of viral latency (GO:0019043)2.40775440
146protein localization to cilium (GO:0061512)2.38951520
147cilium morphogenesis (GO:0060271)2.38858071
148cellular protein complex disassembly (GO:0043624)2.37778755
149transmission of nerve impulse (GO:0019226)2.37409970
150lateral sprouting from an epithelium (GO:0060601)2.36711308
151axonal fasciculation (GO:0007413)2.35817058
152exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.35696165
153organelle disassembly (GO:1903008)2.35417495
154cilium organization (GO:0044782)2.35103216
155viral life cycle (GO:0019058)2.34274349
156cilium assembly (GO:0042384)2.33916113
157DNA ligation (GO:0006266)2.33839723
158spinal cord development (GO:0021510)2.31942461
159regulation of DNA endoreduplication (GO:0032875)2.30652225
160somite development (GO:0061053)2.25194116
161establishment of mitochondrion localization (GO:0051654)2.25169100
162anterograde axon cargo transport (GO:0008089)2.24605589
163resolution of meiotic recombination intermediates (GO:0000712)2.24240021
164short-term memory (GO:0007614)2.24046954
165respiratory chain complex IV assembly (GO:0008535)2.23325725
166translation (GO:0006412)2.23113495
167negative regulation of transcription regulatory region DNA binding (GO:2000678)2.22893261
168intracellular protein transmembrane import (GO:0044743)2.18742926
169cytochrome complex assembly (GO:0017004)2.17515855
170protein complex disassembly (GO:0043241)2.17501311
171macromolecular complex disassembly (GO:0032984)2.16208290
172hindbrain development (GO:0030902)2.14711331
173ATP biosynthetic process (GO:0006754)2.14176876
174purine nucleoside triphosphate biosynthetic process (GO:0009145)2.14124521
175purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.13096389
176hydrogen ion transmembrane transport (GO:1902600)2.11454230
177centriole replication (GO:0007099)2.11400488
178water-soluble vitamin biosynthetic process (GO:0042364)2.10409775

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.65767814
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.70537256
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.99003361
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.69395252
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.57353046
6* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.56144176
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.45841954
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.31708109
9FOXM1_23109430_ChIP-Seq_U2OS_Human3.29102170
10* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.25856697
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.21669260
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.10814152
13MYC_19030024_ChIP-ChIP_MESCs_Mouse3.09286903
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.01892932
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97719956
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.78881730
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.77816211
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.74348389
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.64888314
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.64437327
21XRN2_22483619_ChIP-Seq_HELA_Human2.50390824
22ZNF274_21170338_ChIP-Seq_K562_Hela2.48775769
23* VDR_23849224_ChIP-Seq_CD4+_Human2.38167563
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.32275099
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.31887910
26FUS_26573619_Chip-Seq_HEK293_Human2.29131298
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.28848314
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.28584071
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.27388766
30AR_21909140_ChIP-Seq_LNCAP_Human2.24166520
31VDR_22108803_ChIP-Seq_LS180_Human2.22308379
32DCP1A_22483619_ChIP-Seq_HELA_Human2.20814543
33RBPJ_22232070_ChIP-Seq_NCS_Mouse2.18127460
34EWS_26573619_Chip-Seq_HEK293_Human2.13914228
35THAP11_20581084_ChIP-Seq_MESCs_Mouse2.12357606
36EZH2_22144423_ChIP-Seq_EOC_Human2.11510990
37* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.10364683
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.08005249
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.07926925
40GBX2_23144817_ChIP-Seq_PC3_Human2.06330548
41TTF2_22483619_ChIP-Seq_HELA_Human2.06044089
42FOXP3_21729870_ChIP-Seq_TREG_Human2.02676906
43* MYCN_18555785_ChIP-Seq_MESCs_Mouse2.02227927
44ELK1_19687146_ChIP-ChIP_HELA_Human2.02208418
45* GABP_19822575_ChIP-Seq_HepG2_Human2.01175576
46ELF1_17652178_ChIP-ChIP_JURKAT_Human1.99419383
47ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97288051
48* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.97091846
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.94017102
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.93084588
51TAF15_26573619_Chip-Seq_HEK293_Human1.88770963
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85377663
53E2F1_21310950_ChIP-Seq_MCF-7_Human1.85149704
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.80711065
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.79599669
56CTBP1_25329375_ChIP-Seq_LNCAP_Human1.77680387
57TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.76859060
58ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.75961323
59P300_19829295_ChIP-Seq_ESCs_Human1.75302271
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.75276459
61CTBP2_25329375_ChIP-Seq_LNCAP_Human1.73496947
62CBX2_27304074_Chip-Seq_ESCs_Mouse1.65979874
63FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64537988
64SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.63327770
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.62664856
66IGF1R_20145208_ChIP-Seq_DFB_Human1.59845069
67* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.59606322
68SRF_21415370_ChIP-Seq_HL-1_Mouse1.58509273
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.58075114
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56169598
71RNF2_27304074_Chip-Seq_NSC_Mouse1.55632330
72CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.53938140
73CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.52517626
74SALL1_21062744_ChIP-ChIP_HESCs_Human1.51104988
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.50810140
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46539876
77CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42353088
78KDM5A_27292631_Chip-Seq_BREAST_Human1.42135065
79PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.42086620
80SOX2_18555785_ChIP-Seq_MESCs_Mouse1.41816718
81* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.39463943
82SOX2_16153702_ChIP-ChIP_HESCs_Human1.39344872
83HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38818089
84TP63_19390658_ChIP-ChIP_HaCaT_Human1.34866432
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29170820
86EGR1_19374776_ChIP-ChIP_THP-1_Human1.28971727
87KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.27701043
88SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.27335668
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24974122
90CIITA_25753668_ChIP-Seq_RAJI_Human1.23838090
91SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22108398
92STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22091489
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20100263
94TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19844667
95ELK1_22589737_ChIP-Seq_MCF10A_Human1.18389500
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.18294442
97KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18241454
98FLI1_27457419_Chip-Seq_LIVER_Mouse1.18221656
99* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16747732
100* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14826665
101NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.13698625
102EZH2_27304074_Chip-Seq_ESCs_Mouse1.12734990
103PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12671950
104PIAS1_25552417_ChIP-Seq_VCAP_Human1.12200032
105HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11775520
106REST_21632747_ChIP-Seq_MESCs_Mouse1.11636996
107SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10207088
108GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10039755
109MYC_18940864_ChIP-ChIP_HL60_Human1.09597335
110KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08957408
111TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.08494467
112TCF3_18692474_ChIP-Seq_MEFs_Mouse1.07833569
113NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.07789271
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06965258
115RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06274499
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04138451
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03497208
118POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03282094
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03282094
120* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03175434
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02970299
122SMAD4_21799915_ChIP-Seq_A2780_Human1.02570104
123PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01241917
124CBP_20019798_ChIP-Seq_JUKART_Human1.01235864
125IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01235864
126BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00855228
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98892778
128AR_25329375_ChIP-Seq_VCAP_Human0.98786239
129IRF1_19129219_ChIP-ChIP_H3396_Human0.98592861
130TFEB_21752829_ChIP-Seq_HELA_Human0.98248901
131NANOG_21062744_ChIP-ChIP_HESCs_Human0.97378967
132* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97161660
133NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.96716368
134TP53_22573176_ChIP-Seq_HFKS_Human0.96551765
135SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.96313760
136ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95535526
137CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95388294
138* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.95236831
139ER_23166858_ChIP-Seq_MCF-7_Human0.94972564
140SOX17_20123909_ChIP-Seq_XEN_Mouse0.94613087
141SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.94375633
142SOX9_26525672_Chip-Seq_HEART_Mouse0.94026238
143BCAT_22108803_ChIP-Seq_LS180_Human0.93646027
144HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.92996708
145ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92533691
146CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92509072
147SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.91973298
148KLF5_20875108_ChIP-Seq_MESCs_Mouse0.91619887
149EED_16625203_ChIP-ChIP_MESCs_Mouse0.91288755
150PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.90245432
151RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.90209293
152SOX2_18692474_ChIP-Seq_MEFs_Mouse0.90155726
153RUNX2_22187159_ChIP-Seq_PCA_Human0.89971341
154OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89448758
155KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.89110996
156KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.89110996
157KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.89110996
158ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.87456355
159DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85366963
160ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.84812478
161NANOG_16153702_ChIP-ChIP_HESCs_Human0.84788284
162FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84218710

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.68782584
2MP0004957_abnormal_blastocyst_morpholog4.68074408
3MP0010094_abnormal_chromosome_stability4.47796742
4MP0003111_abnormal_nucleus_morphology4.25617815
5MP0003123_paternal_imprinting4.16294211
6MP0003077_abnormal_cell_cycle3.93645465
7MP0008058_abnormal_DNA_repair3.62452531
8MP0008057_abnormal_DNA_replication3.61263848
9MP0008932_abnormal_embryonic_tissue2.97254511
10MP0008007_abnormal_cellular_replicative2.97180826
11MP0003121_genomic_imprinting2.56073378
12MP0001730_embryonic_growth_arrest2.50320050
13MP0008877_abnormal_DNA_methylation2.41947826
14MP0003718_maternal_effect2.21090440
15MP0000350_abnormal_cell_proliferation2.20692863
16MP0000778_abnormal_nervous_system2.09425335
17MP0003786_premature_aging1.99618547
18MP0003122_maternal_imprinting1.92282712
19MP0003880_abnormal_central_pattern1.90476757
20MP0000566_synostosis1.86788008
21MP0010030_abnormal_orbit_morphology1.86025358
22MP0001697_abnormal_embryo_size1.84818274
23MP0001672_abnormal_embryogenesis/_devel1.84471269
24MP0005380_embryogenesis_phenotype1.84471269
25MP0001984_abnormal_olfaction1.72732710
26MP0002736_abnormal_nociception_after1.71845905
27MP0003984_embryonic_growth_retardation1.63630528
28MP0002085_abnormal_embryonic_tissue1.62897724
29MP0002088_abnormal_embryonic_growth/wei1.60593063
30MP0002080_prenatal_lethality1.58639631
31MP0003806_abnormal_nucleotide_metabolis1.56543566
32MP0002084_abnormal_developmental_patter1.55300399
33MP0010352_gastrointestinal_tract_polyps1.54406884
34MP0006292_abnormal_olfactory_placode1.52853194
35MP0005394_taste/olfaction_phenotype1.51591162
36MP0005499_abnormal_olfactory_system1.51591162
37MP0000631_abnormal_neuroendocrine_gland1.51226920
38MP0004885_abnormal_endolymph1.49666020
39MP0003567_abnormal_fetal_cardiomyocyte1.48878188
40MP0003315_abnormal_perineum_morphology1.48859529
41MP0003119_abnormal_digestive_system1.47928349
42MP0004197_abnormal_fetal_growth/weight/1.43545504
43MP0002233_abnormal_nose_morphology1.42643488
44MP0003890_abnormal_embryonic-extraembry1.42030114
45MP0004859_abnormal_synaptic_plasticity1.39586030
46MP0006276_abnormal_autonomic_nervous1.38390151
47MP0002086_abnormal_extraembryonic_tissu1.37746646
48MP0001293_anophthalmia1.36290746
49MP0010307_abnormal_tumor_latency1.36097508
50MP0002210_abnormal_sex_determination1.27765091
51MP0002160_abnormal_reproductive_system1.25828052
52MP0004270_analgesia1.25708135
53MP0003941_abnormal_skin_development1.24769652
54MP0002735_abnormal_chemical_nociception1.24236791
55MP0002734_abnormal_mechanical_nocicepti1.24083828
56MP0005084_abnormal_gallbladder_morpholo1.23992379
57MP0000537_abnormal_urethra_morphology1.23903171
58MP0002697_abnormal_eye_size1.23874773
59MP0002557_abnormal_social/conspecific_i1.23850149
60MP0000313_abnormal_cell_death1.23457102
61MP0001968_abnormal_touch/_nociception1.22917504
62MP0004142_abnormal_muscle_tone1.21614058
63MP0005551_abnormal_eye_electrophysiolog1.21198282
64MP0003787_abnormal_imprinting1.21150704
65MP0002184_abnormal_innervation1.20888229
66MP0009053_abnormal_anal_canal1.20186011
67MP0002909_abnormal_adrenal_gland1.17270660
68MP0002938_white_spotting1.17158101
69MP0001485_abnormal_pinna_reflex1.17053726
70MP0001486_abnormal_startle_reflex1.16521054
71MP0005253_abnormal_eye_physiology1.16333525
72MP0004133_heterotaxia1.16180548
73MP0001529_abnormal_vocalization1.15451520
74MP0000955_abnormal_spinal_cord1.12609465
75MP0002396_abnormal_hematopoietic_system1.12225750
76MP0009046_muscle_twitch1.12126212
77MP0002272_abnormal_nervous_system1.11101242
78MP0003635_abnormal_synaptic_transmissio1.09771451
79MP0003937_abnormal_limbs/digits/tail_de1.08651951
80MP0009745_abnormal_behavioral_response1.08542978
81MP0002653_abnormal_ependyma_morphology1.08370386
82MP0009379_abnormal_foot_pigmentation1.07802548
83MP0001145_abnormal_male_reproductive1.06959113
84MP0002572_abnormal_emotion/affect_behav1.06526804
85MP0005187_abnormal_penis_morphology1.06376539
86MP0002752_abnormal_somatic_nervous1.03729800
87MP0002163_abnormal_gland_morphology1.01465024
88MP0004147_increased_porphyrin_level1.01360082
89MP0000358_abnormal_cell_content/1.00858478
90MP0003186_abnormal_redox_activity1.00669298
91MP0005423_abnormal_somatic_nervous1.00061911
92MP0000026_abnormal_inner_ear0.99361747
93MP0001299_abnormal_eye_distance/0.99177452
94MP0002152_abnormal_brain_morphology0.99091377
95MP0005391_vision/eye_phenotype0.98828164
96MP0003221_abnormal_cardiomyocyte_apopto0.97778564
97MP0003283_abnormal_digestive_organ0.96515964
98MP0000653_abnormal_sex_gland0.95060890
99MP0002063_abnormal_learning/memory/cond0.94701719
100MP0009697_abnormal_copulation0.94657347
101MP0008995_early_reproductive_senescence0.94290862
102MP0002882_abnormal_neuron_morphology0.94162589
103MP0005389_reproductive_system_phenotype0.93686541
104MP0001286_abnormal_eye_development0.93633664
105MP0005195_abnormal_posterior_eye0.93174572
106MP0000647_abnormal_sebaceous_gland0.92371995
107MP0002234_abnormal_pharynx_morphology0.91789938
108MP0002102_abnormal_ear_morphology0.91226438
109MP0002019_abnormal_tumor_incidence0.90209746
110MP0005377_hearing/vestibular/ear_phenot0.89738847
111MP0003878_abnormal_ear_physiology0.89738847
112MP0000490_abnormal_crypts_of0.88198547
113MP0002111_abnormal_tail_morphology0.87828254
114MP0001929_abnormal_gametogenesis0.87670118
115MP0001119_abnormal_female_reproductive0.85831088
116MP0005646_abnormal_pituitary_gland0.85057380
117MP0002067_abnormal_sensory_capabilities0.85015025
118MP0009672_abnormal_birth_weight0.84260573
119MP0005384_cellular_phenotype0.84204318
120MP0002751_abnormal_autonomic_nervous0.83435627
121MP0004811_abnormal_neuron_physiology0.82607584
122MP0003011_delayed_dark_adaptation0.82268126
123MP0002064_seizures0.81034795
124MP0001324_abnormal_eye_pigmentation0.79949809
125MP0004742_abnormal_vestibular_system0.79480037
126MP0008789_abnormal_olfactory_epithelium0.79297766
127MP0006035_abnormal_mitochondrial_morpho0.77228954
128MP0004808_abnormal_hematopoietic_stem0.73301050
129MP0003755_abnormal_palate_morphology0.71315576
130MP0000049_abnormal_middle_ear0.70590221
131MP0001188_hyperpigmentation0.70339407
132MP0002282_abnormal_trachea_morphology0.70218073
133MP0009333_abnormal_splenocyte_physiolog0.70065621
134MP0000516_abnormal_urinary_system0.69947430
135MP0005367_renal/urinary_system_phenotyp0.69947430
136MP0003861_abnormal_nervous_system0.69626193
137MP0002127_abnormal_cardiovascular_syste0.69384783
138MP0009703_decreased_birth_body0.69351890
139MP0003942_abnormal_urinary_system0.68926733
140MP0001542_abnormal_bone_strength0.67266526
141MP0001727_abnormal_embryo_implantation0.67188096
142MP0005621_abnormal_cell_physiology0.63629399
143MP0000428_abnormal_craniofacial_morphol0.63574799
144MP0006072_abnormal_retinal_apoptosis0.63096177
145MP0003938_abnormal_ear_development0.60662000
146MP0002638_abnormal_pupillary_reflex0.60524749
147MP0005076_abnormal_cell_differentiation0.60352707
148MP0005395_other_phenotype0.60002491
149MP0000432_abnormal_head_morphology0.59690156
150MP0005266_abnormal_metabolism0.58852392
151MP0006054_spinal_hemorrhage0.58504663
152MP0003385_abnormal_body_wall0.58126436
153MP0003115_abnormal_respiratory_system0.57767383
154MP0003936_abnormal_reproductive_system0.57685469
155MP0002114_abnormal_axial_skeleton0.56394797
156MP0003136_yellow_coat_color0.56231418

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.32274946
2Breast hypoplasia (HP:0003187)4.49856138
3Carpal bone hypoplasia (HP:0001498)3.60231289
4Patellar aplasia (HP:0006443)3.58794999
5Abnormality of the labia minora (HP:0012880)3.58032893
6True hermaphroditism (HP:0010459)3.57506125
7Cerebral hypomyelination (HP:0006808)3.52947801
8Reticulocytopenia (HP:0001896)3.50238682
9Pancreatic fibrosis (HP:0100732)3.49742814
10Abnormality of cells of the erythroid lineage (HP:0012130)3.42474848
11Aplasia/Hypoplasia of the patella (HP:0006498)3.42078309
12Degeneration of anterior horn cells (HP:0002398)3.35504521
13Abnormality of the anterior horn cell (HP:0006802)3.35504521
14Oral leukoplakia (HP:0002745)3.28007952
15Rough bone trabeculation (HP:0100670)3.26076680
16Pancreatic cysts (HP:0001737)3.20531178
17Abnormal number of erythroid precursors (HP:0012131)3.11782185
18Molar tooth sign on MRI (HP:0002419)3.10834546
19Abnormality of midbrain morphology (HP:0002418)3.10834546
20Selective tooth agenesis (HP:0001592)3.01829832
21Colon cancer (HP:0003003)3.01177701
22Septo-optic dysplasia (HP:0100842)2.98689074
23Acute encephalopathy (HP:0006846)2.96824895
24Chromsome breakage (HP:0040012)2.92354805
25Absent radius (HP:0003974)2.91410493
26Medial flaring of the eyebrow (HP:0010747)2.90409906
27Increased hepatocellular lipid droplets (HP:0006565)2.88169256
28Nephronophthisis (HP:0000090)2.86946927
29Irregular epiphyses (HP:0010582)2.85244467
30Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.81007615
31Meckel diverticulum (HP:0002245)2.79933858
32Gait imbalance (HP:0002141)2.78858480
33Impulsivity (HP:0100710)2.76019744
34Chromosomal breakage induced by crosslinking agents (HP:0003221)2.75393556
35Aplasia involving forearm bones (HP:0009822)2.72400187
36Absent forearm bone (HP:0003953)2.72400187
37Supernumerary spleens (HP:0009799)2.70552711
38Abnormality of the ileum (HP:0001549)2.69850401
39Volvulus (HP:0002580)2.67470018
40Hypoplasia of the capital femoral epiphysis (HP:0003090)2.63586222
41Congenital primary aphakia (HP:0007707)2.62382842
42Ependymoma (HP:0002888)2.55532553
43Lipid accumulation in hepatocytes (HP:0006561)2.55029669
44Abnormality of the preputium (HP:0100587)2.49438585
45Abnormality of chromosome stability (HP:0003220)2.48733154
46Abnormal trabecular bone morphology (HP:0100671)2.48092586
47Macrocytic anemia (HP:0001972)2.48030252
48Nephrogenic diabetes insipidus (HP:0009806)2.46952896
49Absent thumb (HP:0009777)2.44751257
50Sclerocornea (HP:0000647)2.44523550
51Genital tract atresia (HP:0001827)2.43446546
52Premature graying of hair (HP:0002216)2.42807885
53Medulloblastoma (HP:0002885)2.42165496
54Vaginal atresia (HP:0000148)2.40844136
55Glossoptosis (HP:0000162)2.39355427
56Trismus (HP:0000211)2.39274149
57Aplastic anemia (HP:0001915)2.38928609
58Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.38140876
59Agnosia (HP:0010524)2.38118715
60Abnormal number of incisors (HP:0011064)2.37342520
61Facial cleft (HP:0002006)2.36106131
62Anencephaly (HP:0002323)2.35502684
63Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.32462360
64Absent epiphyses (HP:0010577)2.32462360
65Acute necrotizing encephalopathy (HP:0006965)2.31860984
66Abnormality of the renal medulla (HP:0100957)2.30165808
67Hyperglycinemia (HP:0002154)2.29300878
68Neoplasm of the pancreas (HP:0002894)2.29248561
69Multiple enchondromatosis (HP:0005701)2.28009517
70Increased serum pyruvate (HP:0003542)2.27874936
71Abnormality of glycolysis (HP:0004366)2.27874936
72Anophthalmia (HP:0000528)2.26140954
73Renal Fanconi syndrome (HP:0001994)2.25754909
74Aplasia/Hypoplasia of the tongue (HP:0010295)2.25351354
75Cystic liver disease (HP:0006706)2.23459091
76Aplasia/Hypoplasia of the uvula (HP:0010293)2.22763118
77Horseshoe kidney (HP:0000085)2.21754523
78Microretrognathia (HP:0000308)2.18535967
79Atresia of the external auditory canal (HP:0000413)2.18151474
80Abnormal respiratory motile cilium physiology (HP:0012261)2.17554145
81Premature ovarian failure (HP:0008209)2.17522147
82Secondary amenorrhea (HP:0000869)2.17180166
83Small intestinal stenosis (HP:0012848)2.16255674
84Duodenal stenosis (HP:0100867)2.16255674
85Nephroblastoma (Wilms tumor) (HP:0002667)2.13605480
86Rhabdomyosarcoma (HP:0002859)2.13569746
87Abnormal ciliary motility (HP:0012262)2.13009276
88Cerebral edema (HP:0002181)2.12957960
89Abnormal lung lobation (HP:0002101)2.12626455
90Breast aplasia (HP:0100783)2.12251831
91Hepatocellular necrosis (HP:0001404)2.12038255
92Male pseudohermaphroditism (HP:0000037)2.10065142
93Pallor (HP:0000980)2.07122111
94Abnormal respiratory epithelium morphology (HP:0012253)2.06769695
95Abnormal respiratory motile cilium morphology (HP:0005938)2.06769695
96Absent septum pellucidum (HP:0001331)2.06570306
97Occipital encephalocele (HP:0002085)2.06250427
98Shoulder girdle muscle weakness (HP:0003547)2.05326077
99Cellular immunodeficiency (HP:0005374)2.04592324
100Aplasia/hypoplasia of the humerus (HP:0006507)2.04417126
101Postaxial hand polydactyly (HP:0001162)2.02847036
10211 pairs of ribs (HP:0000878)2.02698410
103Embryonal renal neoplasm (HP:0011794)2.02133083
104Optic nerve hypoplasia (HP:0000609)2.02121273
105Cleft eyelid (HP:0000625)2.01777552
106Postaxial foot polydactyly (HP:0001830)2.01769483
107Abnormal mitochondria in muscle tissue (HP:0008316)2.01368115
108Aplasia/Hypoplasia of the breasts (HP:0010311)2.00308064
109Limb dystonia (HP:0002451)1.99410098
110Triphalangeal thumb (HP:0001199)1.98632990
111Diastasis recti (HP:0001540)1.97952032
112Atrophy/Degeneration involving motor neurons (HP:0007373)1.96783036
113CNS hypomyelination (HP:0003429)1.96276338
114Hepatic necrosis (HP:0002605)1.96181940
115Stenosis of the external auditory canal (HP:0000402)1.95313144
116Intestinal atresia (HP:0011100)1.93701211
117Increased CSF lactate (HP:0002490)1.93699299
118Bile duct proliferation (HP:0001408)1.93396080
119Abnormal biliary tract physiology (HP:0012439)1.93396080
120Deviation of the thumb (HP:0009603)1.93214088
121Myelodysplasia (HP:0002863)1.92769092
122Aplasia/Hypoplasia of the sternum (HP:0006714)1.92285648
123Chronic hepatic failure (HP:0100626)1.91755988
124Preaxial hand polydactyly (HP:0001177)1.91111176
125Sloping forehead (HP:0000340)1.91067817
126Hepatoblastoma (HP:0002884)1.90695700
127Tracheoesophageal fistula (HP:0002575)1.90576838
128Rhinitis (HP:0012384)1.90411171
129Bifid tongue (HP:0010297)1.90318793
130Renal hypoplasia (HP:0000089)1.89391746
131Postnatal microcephaly (HP:0005484)1.88725902
132Proximal placement of thumb (HP:0009623)1.88499073
133Poor coordination (HP:0002370)1.88479695
134Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.87769130
135Rib fusion (HP:0000902)1.85970323
136Bone marrow hypocellularity (HP:0005528)1.85797096
137Mitochondrial inheritance (HP:0001427)1.84292453
138Pelvic girdle muscle weakness (HP:0003749)1.82189110
139Leukodystrophy (HP:0002415)1.81476725
140Myokymia (HP:0002411)1.80326874
141Increased serum lactate (HP:0002151)1.79616585
142Slender long bone (HP:0003100)1.79331736
143Oligodactyly (hands) (HP:0001180)1.77864554
144Progressive macrocephaly (HP:0004481)1.77660117
145Abnormality of renal resorption (HP:0011038)1.76903422
146Abnormality of the duodenum (HP:0002246)1.76241272
147Abnormality of the septum pellucidum (HP:0007375)1.75839681
148Abnormality of the proximal phalanges of the hand (HP:0009834)1.75779104
149Microvesicular hepatic steatosis (HP:0001414)1.75658193
150Decreased testicular size (HP:0008734)1.75618404
151Ectopic kidney (HP:0000086)1.71755810
152Short thumb (HP:0009778)1.71458486
153Abnormality of the fetal cardiovascular system (HP:0010948)1.71126812
154Abnormal umbilical cord blood vessels (HP:0011403)1.71126812
155Single umbilical artery (HP:0001195)1.71126812
156Hypoplasia of the radius (HP:0002984)1.71045618
157Broad foot (HP:0001769)1.70578662
158Glioma (HP:0009733)1.68788556
159Abnormality of abdominal situs (HP:0011620)1.68515328
160Focal motor seizures (HP:0011153)1.67568320
161Bilateral microphthalmos (HP:0007633)1.66718971
162Lissencephaly (HP:0001339)1.66058723
163Short tibia (HP:0005736)1.65480721
164Narrow forehead (HP:0000341)1.64644987
165Optic disc pallor (HP:0000543)1.64245530
166Pendular nystagmus (HP:0012043)1.63979630
167Aganglionic megacolon (HP:0002251)1.63246162
168Micropenis (HP:0000054)1.61365465
169Specific learning disability (HP:0001328)1.60813048
170Scrotal hypoplasia (HP:0000046)1.59576262
171Aplasia/Hypoplasia of the tibia (HP:0005772)1.59188488
172Dandy-Walker malformation (HP:0001305)1.59111980
173Hemivertebrae (HP:0002937)1.58858985
174Small hand (HP:0200055)1.58778865
175Chronic bronchitis (HP:0004469)1.58085675
176Drooling (HP:0002307)1.57263067
177Median cleft lip (HP:0000161)1.56378770
178Holoprosencephaly (HP:0001360)1.56287732
179Oligodactyly (HP:0012165)1.56179710
180Hyperphosphaturia (HP:0003109)1.55986428
181Hypoplastic pelvis (HP:0008839)1.54658969
182Multicystic kidney dysplasia (HP:0000003)1.54195283

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.53046254
2WEE14.38273391
3CDC73.76347111
4TNIK3.51319148
5EIF2AK13.33713782
6CASK3.22968003
7TSSK63.20076131
8SRPK13.03921557
9PLK42.64790038
10NEK12.61577685
11VRK22.61473475
12BRSK22.58899301
13MARK12.50255387
14PLK32.43744228
15STK162.27115825
16NEK22.11223157
17PLK12.09563060
18NME22.04409518
19MKNK11.97926108
20TTK1.97510739
21EIF2AK31.97437184
22PASK1.94874968
23ACVR1B1.91972456
24MAP3K41.88749918
25VRK11.81941346
26CCNB11.79195744
27BRSK11.76984857
28MAP4K21.74776336
29EPHB21.72943955
30CDK191.59367886
31STK38L1.55936437
32PNCK1.55802505
33MKNK21.53602647
34TRIM281.51957760
35AURKB1.51822159
36AKT31.44934090
37TAF11.43053535
38EPHA21.41860463
39CHEK21.41482826
40ATR1.39966784
41MAP2K71.39754587
42DYRK31.38787194
43AURKA1.38284913
44CDK71.37807813
45NTRK21.33653205
46NUAK11.32353368
47TGFBR11.24219052
48CSNK1G21.23942259
49RPS6KB21.22853399
50ZAK1.22547283
51PBK1.17799340
52CDK81.17325479
53EPHA41.16639739
54MAPK131.15530133
55CHEK11.12218703
56WNK41.12047210
57FRK1.11536590
58LATS21.06367782
59PRKCG1.05870070
60NME11.03896071
61STK391.02965328
62BRAF1.02056279
63TESK21.01804047
64UHMK11.00975596
65RPS6KA40.98082368
66MINK10.97012709
67MST40.95966263
68FGFR20.95799950
69OXSR10.94019599
70TESK10.93815492
71PAK40.92046634
72LIMK10.90713818
73MAPK150.90618522
74NTRK10.90350293
75TLK10.89283449
76NTRK30.88954507
77CSNK1G10.88290534
78DYRK20.87829222
79EIF2AK20.84302143
80PIM20.83965756
81PLK20.82638711
82CSNK2A10.82214889
83MAP3K80.81476954
84CSNK2A20.81044994
85CDK20.79385936
86ATM0.76623531
87PRKCI0.75568516
88CDK40.70537770
89BCR0.69482229
90ALK0.68303660
91PAK30.67422973
92INSRR0.64855442
93PAK10.64396557
94CDK10.62570309
95PRKCE0.62199504
96ADRBK20.62193301
97PDK30.62181340
98PDK40.62181340
99ERBB30.61640240
100PDK20.59407252
101SCYL20.58581408
102CDK30.58403042
103STK30.57962159
104CSNK1A1L0.55570685
105DYRK1A0.54936658
106CSNK1E0.52690247
107GRK10.52585222
108FGFR10.51985883
109PINK10.50358392
110MAPKAPK50.49449467
111STK40.48372272
112CAMK1G0.47904434
113YES10.47711906
114CAMK2A0.46713465
115KDR0.46183707
116CDK120.46061887
117PRKACB0.45511131
118STK240.44757647
119ARAF0.44543394
120WNK30.44195336
121CDK50.44067816
122CSNK1A10.42752271
123TAOK20.42556288
124PIM10.41695564
125DAPK10.39463254
126SIK20.38711057
127BMPR1B0.35729995
128MELK0.35264261
129RPS6KA50.33997105
130MAP3K120.33766462
131AKT20.32407095
132ILK0.32086368
133MAP3K30.30433619
134MAP3K110.30113165
135MARK30.29751976
136CDK140.28514448
137PRKDC0.27805309
138ABL20.27579863
139BRD40.26890648
140CDK180.25927582
141CDK11A0.24896187
142STK100.22371413
143CDK150.22161769
144CSNK1G30.21014634
145SIK30.19158591
146MAPK140.18515390

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.43704316
2DNA replication_Homo sapiens_hsa030304.39871520
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.16680253
4RNA polymerase_Homo sapiens_hsa030204.11415625
5Mismatch repair_Homo sapiens_hsa034303.93282255
6Ribosome_Homo sapiens_hsa030103.64143230
7Spliceosome_Homo sapiens_hsa030403.47072782
8RNA transport_Homo sapiens_hsa030133.43095704
9Nucleotide excision repair_Homo sapiens_hsa034202.95468755
10Cell cycle_Homo sapiens_hsa041102.67720595
11Homologous recombination_Homo sapiens_hsa034402.66602141
12Pyrimidine metabolism_Homo sapiens_hsa002402.63798963
13Base excision repair_Homo sapiens_hsa034102.63602935
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.59024647
15Basal transcription factors_Homo sapiens_hsa030222.34234078
16One carbon pool by folate_Homo sapiens_hsa006702.31531637
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.27535865
18Non-homologous end-joining_Homo sapiens_hsa034501.99278783
19Fanconi anemia pathway_Homo sapiens_hsa034601.94506561
20RNA degradation_Homo sapiens_hsa030181.94233126
21Nicotine addiction_Homo sapiens_hsa050331.93916927
22mRNA surveillance pathway_Homo sapiens_hsa030151.82088147
23Steroid biosynthesis_Homo sapiens_hsa001001.66693482
24Purine metabolism_Homo sapiens_hsa002301.55486166
25Propanoate metabolism_Homo sapiens_hsa006401.51994253
26p53 signaling pathway_Homo sapiens_hsa041151.40030465
27Butanoate metabolism_Homo sapiens_hsa006501.39510046
28Huntingtons disease_Homo sapiens_hsa050161.31156484
29Epstein-Barr virus infection_Homo sapiens_hsa051691.28202194
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28031640
31Parkinsons disease_Homo sapiens_hsa050121.26328691
32Protein export_Homo sapiens_hsa030601.24532030
33Oxidative phosphorylation_Homo sapiens_hsa001901.21418662
34Oocyte meiosis_Homo sapiens_hsa041141.18686772
35Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18258788
36Maturity onset diabetes of the young_Homo sapiens_hsa049501.10995614
37Phototransduction_Homo sapiens_hsa047441.10544913
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.04705774
39Vitamin B6 metabolism_Homo sapiens_hsa007500.98465863
40Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97389164
41Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.94113512
42Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93542667
43Cysteine and methionine metabolism_Homo sapiens_hsa002700.92088345
44Fatty acid elongation_Homo sapiens_hsa000620.88932168
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86554428
46Peroxisome_Homo sapiens_hsa041460.84396014
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83331848
48Systemic lupus erythematosus_Homo sapiens_hsa053220.81663543
49Nitrogen metabolism_Homo sapiens_hsa009100.81461912
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78794768
51Biosynthesis of amino acids_Homo sapiens_hsa012300.77636768
52Chemical carcinogenesis_Homo sapiens_hsa052040.76977586
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74195610
54Viral carcinogenesis_Homo sapiens_hsa052030.72562861
55Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71878064
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.70262331
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.69408345
58beta-Alanine metabolism_Homo sapiens_hsa004100.68913011
59Primary bile acid biosynthesis_Homo sapiens_hsa001200.68228029
60Tryptophan metabolism_Homo sapiens_hsa003800.67227309
61Folate biosynthesis_Homo sapiens_hsa007900.66559045
62Taste transduction_Homo sapiens_hsa047420.65599506
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65544074
64GABAergic synapse_Homo sapiens_hsa047270.64414880
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64266974
66Glutamatergic synapse_Homo sapiens_hsa047240.63518074
67Axon guidance_Homo sapiens_hsa043600.62953444
68Hippo signaling pathway_Homo sapiens_hsa043900.61964429
69Collecting duct acid secretion_Homo sapiens_hsa049660.61795777
70Retinol metabolism_Homo sapiens_hsa008300.60319597
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59394741
72Dopaminergic synapse_Homo sapiens_hsa047280.59078941
73Cocaine addiction_Homo sapiens_hsa050300.58768741
74Fatty acid degradation_Homo sapiens_hsa000710.58204919
75Fatty acid metabolism_Homo sapiens_hsa012120.57241183
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55169005
77Fat digestion and absorption_Homo sapiens_hsa049750.55076267
78Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.54955828
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.54257525
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53940246
81Pentose phosphate pathway_Homo sapiens_hsa000300.53025384
82Glutathione metabolism_Homo sapiens_hsa004800.52722905
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52591234
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.52551584
85Circadian entrainment_Homo sapiens_hsa047130.52056467
86Linoleic acid metabolism_Homo sapiens_hsa005910.51728989
87Alzheimers disease_Homo sapiens_hsa050100.51607661
88HTLV-I infection_Homo sapiens_hsa051660.51019335
89Thyroid cancer_Homo sapiens_hsa052160.50347652
90Herpes simplex infection_Homo sapiens_hsa051680.49482077
91Antigen processing and presentation_Homo sapiens_hsa046120.49154853
92TGF-beta signaling pathway_Homo sapiens_hsa043500.48538854
93Amphetamine addiction_Homo sapiens_hsa050310.46417398
94Olfactory transduction_Homo sapiens_hsa047400.45991608
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45837650
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45143419
97Vitamin digestion and absorption_Homo sapiens_hsa049770.44277771
98Ether lipid metabolism_Homo sapiens_hsa005650.43472164
99Selenocompound metabolism_Homo sapiens_hsa004500.43429628
100Morphine addiction_Homo sapiens_hsa050320.42954353
101Carbon metabolism_Homo sapiens_hsa012000.42740498
102Fructose and mannose metabolism_Homo sapiens_hsa000510.41523175
103Alcoholism_Homo sapiens_hsa050340.41398895
104Insulin secretion_Homo sapiens_hsa049110.40780891
105Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40598065
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39733716
107Legionellosis_Homo sapiens_hsa051340.37552241
108Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.37361927
109Basal cell carcinoma_Homo sapiens_hsa052170.36567413
110Hedgehog signaling pathway_Homo sapiens_hsa043400.36315193
111Cyanoamino acid metabolism_Homo sapiens_hsa004600.36196281
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.35785274
113MicroRNAs in cancer_Homo sapiens_hsa052060.33299507
114Metabolic pathways_Homo sapiens_hsa011000.33121274
115Regulation of autophagy_Homo sapiens_hsa041400.28846883
116Galactose metabolism_Homo sapiens_hsa000520.26591519
117N-Glycan biosynthesis_Homo sapiens_hsa005100.26467179
118Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25828433
119Small cell lung cancer_Homo sapiens_hsa052220.25538879
120Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23251274
121Colorectal cancer_Homo sapiens_hsa052100.22414569
122Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.22180811
123HIF-1 signaling pathway_Homo sapiens_hsa040660.20610476
124Arachidonic acid metabolism_Homo sapiens_hsa005900.20262439
125Tight junction_Homo sapiens_hsa045300.19617596
126Wnt signaling pathway_Homo sapiens_hsa043100.18127898
127Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.17317833
128Cardiac muscle contraction_Homo sapiens_hsa042600.16632819
129Vibrio cholerae infection_Homo sapiens_hsa051100.15091887
130Pathways in cancer_Homo sapiens_hsa052000.14870831
131Adherens junction_Homo sapiens_hsa045200.12405761
132Arginine and proline metabolism_Homo sapiens_hsa003300.11609859
133Bladder cancer_Homo sapiens_hsa052190.10917161
134Melanoma_Homo sapiens_hsa052180.10263317
135Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.09809245
136Apoptosis_Homo sapiens_hsa042100.08870706
137Sulfur relay system_Homo sapiens_hsa041220.08300376
138Shigellosis_Homo sapiens_hsa051310.07345338
139Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.06364183
140SNARE interactions in vesicular transport_Homo sapiens_hsa041300.06082693
141PI3K-Akt signaling pathway_Homo sapiens_hsa041510.05251914
142Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.04975760
143Central carbon metabolism in cancer_Homo sapiens_hsa052300.03836354
144Prostate cancer_Homo sapiens_hsa052150.02070792
145Renin-angiotensin system_Homo sapiens_hsa046140.02014256
146Pyruvate metabolism_Homo sapiens_hsa006200.01931194

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »