

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.41244132 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.29289225 |
| 3 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.63272341 |
| 4 | sequestering of actin monomers (GO:0042989) | 5.40297587 |
| 5 | purine deoxyribonucleotide catabolic process (GO:0009155) | 5.36503248 |
| 6 | L-fucose catabolic process (GO:0042355) | 5.31924517 |
| 7 | fucose catabolic process (GO:0019317) | 5.31924517 |
| 8 | L-fucose metabolic process (GO:0042354) | 5.31924517 |
| 9 | actin nucleation (GO:0045010) | 5.07367317 |
| 10 | cytidine deamination (GO:0009972) | 4.93146876 |
| 11 | cytidine metabolic process (GO:0046087) | 4.93146876 |
| 12 | cytidine catabolic process (GO:0006216) | 4.93146876 |
| 13 | platelet dense granule organization (GO:0060155) | 4.85163253 |
| 14 | response to pheromone (GO:0019236) | 4.61393868 |
| 15 | negative regulation of telomere maintenance (GO:0032205) | 4.55244089 |
| 16 | negative regulation of mast cell activation (GO:0033004) | 4.47488913 |
| 17 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.30733183 |
| 18 | base-excision repair, AP site formation (GO:0006285) | 4.22782268 |
| 19 | mast cell degranulation (GO:0043303) | 4.20961170 |
| 20 | mast cell activation involved in immune response (GO:0002279) | 4.20961170 |
| 21 | immunoglobulin mediated immune response (GO:0016064) | 3.89180675 |
| 22 | cullin deneddylation (GO:0010388) | 3.79606906 |
| 23 | protein neddylation (GO:0045116) | 3.71943359 |
| 24 | negative T cell selection (GO:0043383) | 3.65984124 |
| 25 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.63178429 |
| 26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.53123988 |
| 27 | cellular response to interleukin-15 (GO:0071350) | 3.53015992 |
| 28 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.47804941 |
| 29 | ATP synthesis coupled proton transport (GO:0015986) | 3.47112886 |
| 30 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.47112886 |
| 31 | mast cell activation (GO:0045576) | 3.42809361 |
| 32 | protein deneddylation (GO:0000338) | 3.42758262 |
| 33 | S-adenosylmethionine metabolic process (GO:0046500) | 3.38516934 |
| 34 | deoxyribonucleotide catabolic process (GO:0009264) | 3.35444733 |
| 35 | neuronal action potential propagation (GO:0019227) | 3.30282734 |
| 36 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.29981123 |
| 37 | negative thymic T cell selection (GO:0045060) | 3.28048412 |
| 38 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.24382958 |
| 39 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.23586495 |
| 40 | positive thymic T cell selection (GO:0045059) | 3.22007326 |
| 41 | mannosylation (GO:0097502) | 3.16997525 |
| 42 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.16113121 |
| 43 | tyrosine phosphorylation of STAT protein (GO:0007260) | 3.14786282 |
| 44 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.06131218 |
| 45 | deoxyribose phosphate catabolic process (GO:0046386) | 3.06030222 |
| 46 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.05150633 |
| 47 | GPI anchor biosynthetic process (GO:0006506) | 3.04746157 |
| 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.03261737 |
| 49 | glutathione biosynthetic process (GO:0006750) | 3.02390260 |
| 50 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.00455231 |
| 51 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.99715100 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.99715100 |
| 53 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.99460101 |
| 54 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.99323142 |
| 55 | inositol phosphate dephosphorylation (GO:0046855) | 2.99323142 |
| 56 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 2.98148239 |
| 57 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.97993514 |
| 58 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.97993514 |
| 59 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.97993514 |
| 60 | plasma membrane fusion (GO:0045026) | 2.94227568 |
| 61 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.93383024 |
| 62 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.92611818 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.92302166 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.92302166 |
| 65 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.91506366 |
| 66 | GPI anchor metabolic process (GO:0006505) | 2.91444207 |
| 67 | B cell mediated immunity (GO:0019724) | 2.90241444 |
| 68 | proteasome assembly (GO:0043248) | 2.88274062 |
| 69 | regulation of regulatory T cell differentiation (GO:0045589) | 2.86179819 |
| 70 | positive T cell selection (GO:0043368) | 2.85272846 |
| 71 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.83821394 |
| 72 | regulation of gamma-delta T cell activation (GO:0046643) | 2.83813122 |
| 73 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.81924879 |
| 74 | response to interferon-beta (GO:0035456) | 2.80045921 |
| 75 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.79428100 |
| 76 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.79428100 |
| 77 | amino acid salvage (GO:0043102) | 2.79356201 |
| 78 | L-methionine salvage (GO:0071267) | 2.79356201 |
| 79 | L-methionine biosynthetic process (GO:0071265) | 2.79356201 |
| 80 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.79031261 |
| 81 | nonribosomal peptide biosynthetic process (GO:0019184) | 2.77490574 |
| 82 | positive regulation of antigen processing and presentation (GO:0002579) | 2.76971657 |
| 83 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.76093584 |
| 84 | lysosome localization (GO:0032418) | 2.75411479 |
| 85 | T cell receptor signaling pathway (GO:0050852) | 2.74921269 |
| 86 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.74880090 |
| 87 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.74842778 |
| 88 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.74359991 |
| 89 | positive regulation of cell killing (GO:0031343) | 2.70675673 |
| 90 | response to xenobiotic stimulus (GO:0009410) | 2.69494251 |
| 91 | response to interleukin-15 (GO:0070672) | 2.69200967 |
| 92 | sulfation (GO:0051923) | 2.68663754 |
| 93 | T cell costimulation (GO:0031295) | 2.66180884 |
| 94 | negative regulation of T cell apoptotic process (GO:0070233) | 2.65952390 |
| 95 | fucosylation (GO:0036065) | 2.63365187 |
| 96 | inositol phosphate catabolic process (GO:0071545) | 2.63104087 |
| 97 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.62931289 |
| 98 | lymphocyte costimulation (GO:0031294) | 2.62733201 |
| 99 | interferon-gamma secretion (GO:0072643) | 2.60965316 |
| 100 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.57940747 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.52639123 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.35961533 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.93416368 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.34116908 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.30322455 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.27018161 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.01455330 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.98981378 |
| 9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.54172426 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.52050514 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.42657582 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.41287955 |
| 13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.35229021 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.34876911 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.32041291 |
| 16 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.29691503 |
| 17 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.24756897 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.20567683 |
| 19 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.13954870 |
| 20 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.13048122 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.07878142 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.95181093 |
| 23 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.94063258 |
| 24 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.93536682 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.93049380 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91747882 |
| 27 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.89096187 |
| 28 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.88402430 |
| 29 | GATA3_26560356_Chip-Seq_TH2_Human | 1.88129747 |
| 30 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.86274167 |
| 31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.73296496 |
| 32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.73023469 |
| 33 | MYB_26560356_Chip-Seq_TH2_Human | 1.71127968 |
| 34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.69415391 |
| 35 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.65446671 |
| 36 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.61346694 |
| 37 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.59810480 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.55223701 |
| 39 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.51115810 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.48854253 |
| 41 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.48015886 |
| 42 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.47661791 |
| 43 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.43709626 |
| 44 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.41645310 |
| 45 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.38422343 |
| 46 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.37690126 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.36082739 |
| 48 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.33803026 |
| 49 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.31276321 |
| 50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.30121736 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30098390 |
| 52 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29964081 |
| 53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.29720000 |
| 54 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27855496 |
| 55 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.25842661 |
| 56 | ERA_21632823_ChIP-Seq_H3396_Human | 1.24114401 |
| 57 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24067856 |
| 58 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.23751040 |
| 59 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.23476222 |
| 60 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.22805175 |
| 61 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22446162 |
| 62 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.22299342 |
| 63 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.22217744 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.21138057 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20326337 |
| 66 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17049749 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16069105 |
| 68 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.14170502 |
| 69 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.12841673 |
| 70 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.12680049 |
| 71 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.09412136 |
| 72 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.08604792 |
| 73 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06547164 |
| 74 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.05784995 |
| 75 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04643345 |
| 76 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04643345 |
| 77 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.04358434 |
| 78 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.02625593 |
| 79 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.01678896 |
| 80 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01037708 |
| 81 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.00700850 |
| 82 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00211710 |
| 83 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.99022176 |
| 84 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.97516303 |
| 85 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.96989647 |
| 86 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96802174 |
| 87 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.96028339 |
| 88 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.95948180 |
| 89 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94390018 |
| 90 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.94147624 |
| 91 | P300_27268052_Chip-Seq_Bcells_Human | 0.93831591 |
| 92 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92560606 |
| 93 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.91582520 |
| 94 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90459231 |
| 95 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.90375939 |
| 96 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.89035172 |
| 97 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.87787580 |
| 98 | MYB_26560356_Chip-Seq_TH1_Human | 0.87695608 |
| 99 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.87090004 |
| 100 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86897813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.33932212 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.89408445 |
| 3 | MP0002822_catalepsy | 3.37295619 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.31365890 |
| 5 | MP0004147_increased_porphyrin_level | 2.94970977 |
| 6 | MP0009785_altered_susceptibility_to | 2.70734757 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.67342218 |
| 8 | MP0002102_abnormal_ear_morphology | 2.58339303 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.40124739 |
| 10 | MP0002166_altered_tumor_susceptibility | 2.32039783 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.25699567 |
| 12 | MP0000685_abnormal_immune_system | 2.05231033 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.04590450 |
| 14 | MP0003763_abnormal_thymus_physiology | 2.00320994 |
| 15 | MP0000465_gastrointestinal_hemorrhage | 2.00245242 |
| 16 | MP0001800_abnormal_humoral_immune | 1.95611093 |
| 17 | MP0003724_increased_susceptibility_to | 1.93399605 |
| 18 | MP0002006_tumorigenesis | 1.80443231 |
| 19 | MP0003195_calcinosis | 1.78909269 |
| 20 | MP0002723_abnormal_immune_serum | 1.78288145 |
| 21 | MP0005025_abnormal_response_to | 1.77801569 |
| 22 | MP0002420_abnormal_adaptive_immunity | 1.74658238 |
| 23 | MP0009764_decreased_sensitivity_to | 1.73848824 |
| 24 | MP0004885_abnormal_endolymph | 1.73199784 |
| 25 | MP0001819_abnormal_immune_cell | 1.71288231 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.71175185 |
| 27 | MP0000015_abnormal_ear_pigmentation | 1.70113791 |
| 28 | MP0001790_abnormal_immune_system | 1.67678111 |
| 29 | MP0005387_immune_system_phenotype | 1.67678111 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.65769085 |
| 31 | MP0002736_abnormal_nociception_after | 1.63290402 |
| 32 | MP0003866_abnormal_defecation | 1.60492736 |
| 33 | MP0003646_muscle_fatigue | 1.58475737 |
| 34 | MP0002452_abnormal_antigen_presenting | 1.55393542 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.55318424 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.50762169 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.46287475 |
| 38 | MP0001905_abnormal_dopamine_level | 1.44271277 |
| 39 | MP0005085_abnormal_gallbladder_physiolo | 1.43815850 |
| 40 | MP0008872_abnormal_physiological_respon | 1.43643222 |
| 41 | MP0004043_abnormal_pH_regulation | 1.39324885 |
| 42 | MP0005410_abnormal_fertilization | 1.35937353 |
| 43 | MP0002933_joint_inflammation | 1.29840206 |
| 44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.28896162 |
| 45 | MP0002405_respiratory_system_inflammati | 1.27213376 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.25467269 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.23658395 |
| 48 | MP0001986_abnormal_taste_sensitivity | 1.19317938 |
| 49 | MP0005174_abnormal_tail_pigmentation | 1.18941518 |
| 50 | MP0000716_abnormal_immune_system | 1.18186394 |
| 51 | MP0002398_abnormal_bone_marrow | 1.18058752 |
| 52 | MP0005464_abnormal_platelet_physiology | 1.17205859 |
| 53 | MP0006036_abnormal_mitochondrial_physio | 1.15900854 |
| 54 | MP0003436_decreased_susceptibility_to | 1.15378725 |
| 55 | MP0002095_abnormal_skin_pigmentation | 1.13448231 |
| 56 | MP0001188_hyperpigmentation | 1.13325668 |
| 57 | MP0003878_abnormal_ear_physiology | 1.11105714 |
| 58 | MP0005377_hearing/vestibular/ear_phenot | 1.11105714 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.10712536 |
| 60 | MP0002722_abnormal_immune_system | 1.09670729 |
| 61 | MP0003693_abnormal_embryo_hatching | 1.08747300 |
| 62 | MP0004145_abnormal_muscle_electrophysio | 1.08379274 |
| 63 | MP0010155_abnormal_intestine_physiology | 1.07454511 |
| 64 | MP0003786_premature_aging | 1.02295713 |
| 65 | MP0005253_abnormal_eye_physiology | 1.01848937 |
| 66 | MP0001542_abnormal_bone_strength | 1.01560580 |
| 67 | MP0005360_urolithiasis | 1.01088039 |
| 68 | MP0002419_abnormal_innate_immunity | 1.00840078 |
| 69 | MP0001919_abnormal_reproductive_system | 0.99240297 |
| 70 | MP0002272_abnormal_nervous_system | 0.97241426 |
| 71 | MP0002139_abnormal_hepatobiliary_system | 0.95988919 |
| 72 | MP0003638_abnormal_response/metabolism_ | 0.95673520 |
| 73 | MP0001764_abnormal_homeostasis | 0.94966107 |
| 74 | MP0006276_abnormal_autonomic_nervous | 0.93347633 |
| 75 | MP0005084_abnormal_gallbladder_morpholo | 0.92396350 |
| 76 | MP0003011_delayed_dark_adaptation | 0.92078545 |
| 77 | MP0002429_abnormal_blood_cell | 0.91860440 |
| 78 | MP0001533_abnormal_skeleton_physiology | 0.89646835 |
| 79 | MP0001873_stomach_inflammation | 0.89379285 |
| 80 | MP0006082_CNS_inflammation | 0.89046133 |
| 81 | MP0002837_dystrophic_cardiac_calcinosis | 0.86324443 |
| 82 | MP0009745_abnormal_behavioral_response | 0.85736457 |
| 83 | MP0001501_abnormal_sleep_pattern | 0.84842706 |
| 84 | MP0002876_abnormal_thyroid_physiology | 0.84662163 |
| 85 | MP0006054_spinal_hemorrhage | 0.84223312 |
| 86 | MP0008469_abnormal_protein_level | 0.83653978 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.82140707 |
| 88 | MP0000703_abnormal_thymus_morphology | 0.81286171 |
| 89 | MP0005646_abnormal_pituitary_gland | 0.81122232 |
| 90 | MP0005332_abnormal_amino_acid | 0.80068566 |
| 91 | MP0001243_abnormal_dermal_layer | 0.79244443 |
| 92 | MP0005166_decreased_susceptibility_to | 0.79194504 |
| 93 | MP0002234_abnormal_pharynx_morphology | 0.77696372 |
| 94 | MP0005365_abnormal_bile_salt | 0.76451047 |
| 95 | MP0009643_abnormal_urine_homeostasis | 0.75336467 |
| 96 | MP0000604_amyloidosis | 0.75326373 |
| 97 | MP0003252_abnormal_bile_duct | 0.73570479 |
| 98 | MP0004742_abnormal_vestibular_system | 0.73390125 |
| 99 | MP0005167_abnormal_blood-brain_barrier | 0.70427141 |
| 100 | MP0001765_abnormal_ion_homeostasis | 0.69876701 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IgG deficiency (HP:0004315) | 4.39818180 |
| 2 | Hypomagnesemia (HP:0002917) | 4.37604733 |
| 3 | Prostate neoplasm (HP:0100787) | 4.12552739 |
| 4 | Abnormality of midbrain morphology (HP:0002418) | 4.02621849 |
| 5 | Molar tooth sign on MRI (HP:0002419) | 4.02621849 |
| 6 | Abnormality of the prostate (HP:0008775) | 3.87891688 |
| 7 | Abnormality of magnesium homeostasis (HP:0004921) | 3.87348335 |
| 8 | Abolished electroretinogram (ERG) (HP:0000550) | 3.80576348 |
| 9 | Increased IgM level (HP:0003496) | 3.79389127 |
| 10 | Retinal dysplasia (HP:0007973) | 3.53948656 |
| 11 | Amyotrophic lateral sclerosis (HP:0007354) | 3.44362783 |
| 12 | Aplastic anemia (HP:0001915) | 3.26396426 |
| 13 | Hypoproteinemia (HP:0003075) | 3.12914208 |
| 14 | 3-Methylglutaconic aciduria (HP:0003535) | 3.12625412 |
| 15 | Abnormality of T cell number (HP:0011839) | 3.02855093 |
| 16 | Stomatitis (HP:0010280) | 3.02124730 |
| 17 | T lymphocytopenia (HP:0005403) | 3.01865520 |
| 18 | Severe combined immunodeficiency (HP:0004430) | 3.01649556 |
| 19 | Pulmonary fibrosis (HP:0002206) | 2.94040494 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 2.94025651 |
| 21 | Type 2 muscle fiber atrophy (HP:0003554) | 2.80761631 |
| 22 | Hepatocellular necrosis (HP:0001404) | 2.80706333 |
| 23 | Abnormality of T cells (HP:0002843) | 2.80533165 |
| 24 | Increased serum lactate (HP:0002151) | 2.80255962 |
| 25 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.79345877 |
| 26 | Mitochondrial inheritance (HP:0001427) | 2.75639545 |
| 27 | Muscle fiber atrophy (HP:0100295) | 2.71376924 |
| 28 | Polyuria (HP:0000103) | 2.63259803 |
| 29 | Hepatic necrosis (HP:0002605) | 2.59140414 |
| 30 | Pustule (HP:0200039) | 2.57666962 |
| 31 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.56709789 |
| 32 | Acute encephalopathy (HP:0006846) | 2.55221376 |
| 33 | Opisthotonus (HP:0002179) | 2.54324835 |
| 34 | Stomach cancer (HP:0012126) | 2.48477410 |
| 35 | Alkalosis (HP:0001948) | 2.48206859 |
| 36 | Type I transferrin isoform profile (HP:0003642) | 2.44543065 |
| 37 | Congenital stationary night blindness (HP:0007642) | 2.42018968 |
| 38 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.41543322 |
| 39 | Abnormality of eosinophils (HP:0001879) | 2.41099122 |
| 40 | Abnormality of B cell number (HP:0010975) | 2.39769551 |
| 41 | Progressive macrocephaly (HP:0004481) | 2.36997865 |
| 42 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.36950192 |
| 43 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.36950192 |
| 44 | Abnormal protein glycosylation (HP:0012346) | 2.36950192 |
| 45 | Abnormal glycosylation (HP:0012345) | 2.36950192 |
| 46 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.34857636 |
| 47 | Generalized aminoaciduria (HP:0002909) | 2.33299202 |
| 48 | Thyroiditis (HP:0100646) | 2.32826214 |
| 49 | Increased CSF lactate (HP:0002490) | 2.32513141 |
| 50 | Agitation (HP:0000713) | 2.28988814 |
| 51 | Lactic acidosis (HP:0003128) | 2.28431975 |
| 52 | Attenuation of retinal blood vessels (HP:0007843) | 2.26299728 |
| 53 | Combined immunodeficiency (HP:0005387) | 2.25284539 |
| 54 | Abnormal urine output (HP:0012590) | 2.22102173 |
| 55 | Renal salt wasting (HP:0000127) | 2.21939979 |
| 56 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.18902060 |
| 57 | Cerebral palsy (HP:0100021) | 2.16939532 |
| 58 | Parakeratosis (HP:0001036) | 2.12095256 |
| 59 | Abnormality of T cell physiology (HP:0011840) | 2.08657661 |
| 60 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.03731305 |
| 61 | Pancreatic fibrosis (HP:0100732) | 2.03649605 |
| 62 | Abnormality of the renal cortex (HP:0011035) | 2.03104091 |
| 63 | Chronic diarrhea (HP:0002028) | 2.02928177 |
| 64 | Pancreatic cysts (HP:0001737) | 2.02517871 |
| 65 | Tetany (HP:0001281) | 2.02244592 |
| 66 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.00480844 |
| 67 | Myositis (HP:0100614) | 2.00198141 |
| 68 | Chronic sinusitis (HP:0011109) | 1.99971609 |
| 69 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.99425081 |
| 70 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.99425081 |
| 71 | Encephalitis (HP:0002383) | 1.99189017 |
| 72 | Microvesicular hepatic steatosis (HP:0001414) | 1.91016701 |
| 73 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.90186583 |
| 74 | Joint swelling (HP:0001386) | 1.90185099 |
| 75 | Broad-based gait (HP:0002136) | 1.89268581 |
| 76 | Autoimmune hemolytic anemia (HP:0001890) | 1.88887666 |
| 77 | Metabolic alkalosis (HP:0200114) | 1.87831346 |
| 78 | True hermaphroditism (HP:0010459) | 1.87695253 |
| 79 | Oral leukoplakia (HP:0002745) | 1.86912516 |
| 80 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.86383673 |
| 81 | Cerebral edema (HP:0002181) | 1.86023245 |
| 82 | Hypokalemic alkalosis (HP:0001949) | 1.84569333 |
| 83 | Nephronophthisis (HP:0000090) | 1.83075489 |
| 84 | Abnormality of renal excretion (HP:0011036) | 1.82781621 |
| 85 | Increased intramyocellular lipid droplets (HP:0012240) | 1.82736315 |
| 86 | Pancytopenia (HP:0001876) | 1.81701136 |
| 87 | Infantile muscular hypotonia (HP:0008947) | 1.81246491 |
| 88 | Periorbital edema (HP:0100539) | 1.80389261 |
| 89 | Delayed CNS myelination (HP:0002188) | 1.79143721 |
| 90 | Pulmonary infiltrates (HP:0002113) | 1.78415518 |
| 91 | Optic disc pallor (HP:0000543) | 1.77666231 |
| 92 | Abnormal drinking behavior (HP:0030082) | 1.77184543 |
| 93 | Polydipsia (HP:0001959) | 1.77184543 |
| 94 | Facial edema (HP:0000282) | 1.76832852 |
| 95 | Reduced antithrombin III activity (HP:0001976) | 1.76679702 |
| 96 | Abnormality of male internal genitalia (HP:0000022) | 1.75355012 |
| 97 | Acute hepatic failure (HP:0006554) | 1.75048523 |
| 98 | Lethargy (HP:0001254) | 1.74349489 |
| 99 | Progressive neurologic deterioration (HP:0002344) | 1.72987116 |
| 100 | Cellular immunodeficiency (HP:0005374) | 1.71629686 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.77181459 |
| 2 | TESK2 | 4.54365007 |
| 3 | TAOK3 | 4.10526579 |
| 4 | TLK1 | 3.57590255 |
| 5 | ZAK | 3.20687863 |
| 6 | TESK1 | 2.89528938 |
| 7 | KIT | 2.88606600 |
| 8 | MAP3K12 | 2.74203583 |
| 9 | MAP4K1 | 2.35964462 |
| 10 | VRK2 | 2.20355349 |
| 11 | LIMK1 | 2.20015366 |
| 12 | TXK | 2.20009474 |
| 13 | TIE1 | 2.13781026 |
| 14 | GRK1 | 2.11257148 |
| 15 | GRK6 | 2.04583618 |
| 16 | MAP4K2 | 1.82765519 |
| 17 | ADRBK2 | 1.79372110 |
| 18 | BCKDK | 1.77381914 |
| 19 | SCYL2 | 1.69834919 |
| 20 | MST4 | 1.60002425 |
| 21 | SYK | 1.55817135 |
| 22 | PINK1 | 1.52964931 |
| 23 | FES | 1.52102870 |
| 24 | MYLK | 1.33327964 |
| 25 | FER | 1.28291107 |
| 26 | VRK1 | 1.21437503 |
| 27 | MAPKAPK3 | 1.19891507 |
| 28 | DAPK1 | 1.15523310 |
| 29 | CSNK1G3 | 1.15258472 |
| 30 | ITK | 1.13915343 |
| 31 | MUSK | 1.07976474 |
| 32 | TBK1 | 1.07660753 |
| 33 | CSNK1A1L | 1.05158313 |
| 34 | PHKG1 | 1.03367454 |
| 35 | PHKG2 | 1.03367454 |
| 36 | RPS6KA4 | 0.97147547 |
| 37 | NUAK1 | 0.95521385 |
| 38 | TEC | 0.94186585 |
| 39 | MATK | 0.91774114 |
| 40 | CSNK1G1 | 0.90899749 |
| 41 | CDK8 | 0.89560184 |
| 42 | STK16 | 0.87999222 |
| 43 | TRIM28 | 0.86888813 |
| 44 | LYN | 0.86879736 |
| 45 | WNK3 | 0.85586302 |
| 46 | IKBKE | 0.84285750 |
| 47 | TNK2 | 0.83837372 |
| 48 | NME1 | 0.82574257 |
| 49 | MAP2K6 | 0.82514237 |
| 50 | IKBKB | 0.80750863 |
| 51 | DYRK2 | 0.80708755 |
| 52 | CAMKK1 | 0.79835790 |
| 53 | CSNK1G2 | 0.77186251 |
| 54 | BTK | 0.76683838 |
| 55 | RPS6KA5 | 0.74534066 |
| 56 | MAP3K11 | 0.72313879 |
| 57 | ZAP70 | 0.66600958 |
| 58 | GRK5 | 0.65687412 |
| 59 | LCK | 0.64689087 |
| 60 | CSK | 0.61632829 |
| 61 | MAPK13 | 0.61010285 |
| 62 | MAP2K7 | 0.60713762 |
| 63 | PASK | 0.59455278 |
| 64 | FRK | 0.55548924 |
| 65 | PRKCQ | 0.55134678 |
| 66 | WNK4 | 0.54518020 |
| 67 | BUB1 | 0.54299451 |
| 68 | INSRR | 0.52775562 |
| 69 | CSF1R | 0.52414372 |
| 70 | SRPK1 | 0.50538696 |
| 71 | RIPK4 | 0.50056319 |
| 72 | JAK3 | 0.49365717 |
| 73 | ADRBK1 | 0.46857982 |
| 74 | CAMKK2 | 0.45981526 |
| 75 | OXSR1 | 0.44441722 |
| 76 | PTK2B | 0.44235380 |
| 77 | GRK7 | 0.43952013 |
| 78 | PRKCI | 0.43517663 |
| 79 | PIM1 | 0.41894879 |
| 80 | BMPR1B | 0.41191657 |
| 81 | AURKA | 0.40309997 |
| 82 | SIK3 | 0.39662109 |
| 83 | PLK2 | 0.39300549 |
| 84 | EIF2AK2 | 0.38665407 |
| 85 | ABL1 | 0.38535694 |
| 86 | BCR | 0.37946080 |
| 87 | DAPK3 | 0.34927746 |
| 88 | PIM2 | 0.34255735 |
| 89 | JAK1 | 0.34135688 |
| 90 | ATR | 0.33359298 |
| 91 | HCK | 0.33314435 |
| 92 | PRKCA | 0.33261819 |
| 93 | CDK3 | 0.31989549 |
| 94 | BLK | 0.31566192 |
| 95 | MAP3K5 | 0.30431101 |
| 96 | IGF1R | 0.25238340 |
| 97 | CSNK1A1 | 0.23893009 |
| 98 | MAPKAPK5 | 0.21909984 |
| 99 | PRKACA | 0.21458105 |
| 100 | MAP3K4 | 0.21350338 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.93742605 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.72312680 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.55463037 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.55296520 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.51323858 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.23995632 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.01043556 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.93235850 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.75483603 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.42737876 |
| 11 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.21346330 |
| 12 | Viral myocarditis_Homo sapiens_hsa05416 | 2.03502093 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.02481540 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.01628080 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.97699389 |
| 16 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.87384934 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.66324718 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.59794459 |
| 19 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.37778460 |
| 20 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.31784516 |
| 21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.31053547 |
| 22 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.27398837 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25393985 |
| 24 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.20733578 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.20390524 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.19941914 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.18271422 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.17568949 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.11453303 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.06753392 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.03364026 |
| 32 | Base excision repair_Homo sapiens_hsa03410 | 1.02220448 |
| 33 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.01063205 |
| 34 | Leishmaniasis_Homo sapiens_hsa05140 | 0.96788012 |
| 35 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.96198671 |
| 36 | DNA replication_Homo sapiens_hsa03030 | 0.93981338 |
| 37 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91289288 |
| 38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.87235117 |
| 39 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.86643948 |
| 40 | Shigellosis_Homo sapiens_hsa05131 | 0.86030949 |
| 41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83538215 |
| 42 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.80751279 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.80605247 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.79258448 |
| 45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79022486 |
| 46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.78984186 |
| 47 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.76740203 |
| 48 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75641047 |
| 49 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.75462955 |
| 50 | Protein export_Homo sapiens_hsa03060 | 0.74256020 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73209526 |
| 52 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.72771213 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70263854 |
| 54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70058432 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.67535462 |
| 56 | RNA degradation_Homo sapiens_hsa03018 | 0.65923392 |
| 57 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.65691089 |
| 58 | Mismatch repair_Homo sapiens_hsa03430 | 0.65364815 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.63065647 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.62804760 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62585906 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.62323078 |
| 63 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62199542 |
| 64 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.61446385 |
| 65 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.61117561 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58746746 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.58617885 |
| 68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.58538977 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57905692 |
| 70 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.56570423 |
| 71 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56524301 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54262506 |
| 73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53310825 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52503713 |
| 75 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.51368798 |
| 76 | Phagosome_Homo sapiens_hsa04145 | 0.51353826 |
| 77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47702024 |
| 78 | Legionellosis_Homo sapiens_hsa05134 | 0.47411921 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44873065 |
| 80 | Homologous recombination_Homo sapiens_hsa03440 | 0.42231742 |
| 81 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39839712 |
| 82 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39563051 |
| 83 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38975340 |
| 84 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.38333160 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37191981 |
| 86 | Tuberculosis_Homo sapiens_hsa05152 | 0.36594105 |
| 87 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.34533874 |
| 88 | Salmonella infection_Homo sapiens_hsa05132 | 0.33834782 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.33733489 |
| 90 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.32930487 |
| 91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.29990398 |
| 92 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.28480223 |
| 93 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.27999490 |
| 94 | Spliceosome_Homo sapiens_hsa03040 | 0.27705530 |
| 95 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.26716473 |
| 96 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26506084 |
| 97 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25824517 |
| 98 | Malaria_Homo sapiens_hsa05144 | 0.24652063 |
| 99 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.23994154 |
| 100 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.21131300 |

