

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sequestering of actin monomers (GO:0042989) | 5.91741972 |
| 2 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.45789930 |
| 3 | protein maturation by protein folding (GO:0022417) | 5.30118662 |
| 4 | DNA deamination (GO:0045006) | 4.75718387 |
| 5 | actin nucleation (GO:0045010) | 4.66141966 |
| 6 | response to interferon-beta (GO:0035456) | 4.48311672 |
| 7 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.45578692 |
| 8 | positive regulation of actin filament depolymerization (GO:0030836) | 4.37763174 |
| 9 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.25927332 |
| 10 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.20392553 |
| 11 | viral mRNA export from host cell nucleus (GO:0046784) | 4.19160519 |
| 12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.17978360 |
| 13 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 4.15901924 |
| 14 | protein neddylation (GO:0045116) | 4.12256636 |
| 15 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.11021908 |
| 16 | platelet dense granule organization (GO:0060155) | 4.09630015 |
| 17 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.07239626 |
| 18 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.07239626 |
| 19 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.04443680 |
| 20 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.04443680 |
| 21 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.04443680 |
| 22 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.04100971 |
| 23 | establishment of integrated proviral latency (GO:0075713) | 3.98251924 |
| 24 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.92053492 |
| 25 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.92053492 |
| 26 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.91555405 |
| 27 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.86379174 |
| 28 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.81855963 |
| 29 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.80980687 |
| 30 | ATP synthesis coupled proton transport (GO:0015986) | 3.80980687 |
| 31 | regulation of interleukin-8 secretion (GO:2000482) | 3.80281209 |
| 32 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.79353078 |
| 33 | proteasome assembly (GO:0043248) | 3.78711949 |
| 34 | establishment of viral latency (GO:0019043) | 3.77463254 |
| 35 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.71726868 |
| 36 | negative regulation of ligase activity (GO:0051352) | 3.71726868 |
| 37 | cellular response to interferon-beta (GO:0035458) | 3.61901400 |
| 38 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.56825367 |
| 39 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.53716059 |
| 40 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.53415208 |
| 41 | protein deneddylation (GO:0000338) | 3.43950335 |
| 42 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.40577920 |
| 43 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.34953862 |
| 44 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.34953862 |
| 45 | cytidine metabolic process (GO:0046087) | 3.34240569 |
| 46 | cytidine catabolic process (GO:0006216) | 3.34240569 |
| 47 | cytidine deamination (GO:0009972) | 3.34240569 |
| 48 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.31793018 |
| 49 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.30277152 |
| 50 | response to gravity (GO:0009629) | 3.29268427 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.28111360 |
| 52 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.27838336 |
| 53 | electron transport chain (GO:0022900) | 3.27318912 |
| 54 | respiratory electron transport chain (GO:0022904) | 3.26971225 |
| 55 | cullin deneddylation (GO:0010388) | 3.22852162 |
| 56 | positive regulation of ligase activity (GO:0051351) | 3.20088269 |
| 57 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.17715526 |
| 58 | regulation of cellular amine metabolic process (GO:0033238) | 3.16198059 |
| 59 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.13614226 |
| 60 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.04956658 |
| 61 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.03894859 |
| 62 | adenosine metabolic process (GO:0046085) | 3.01982879 |
| 63 | positive regulation of cell cycle arrest (GO:0071158) | 3.00999997 |
| 64 | interferon-gamma secretion (GO:0072643) | 2.99169696 |
| 65 | positive regulation of defense response to virus by host (GO:0002230) | 2.97805865 |
| 66 | protein complex biogenesis (GO:0070271) | 2.94845687 |
| 67 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 2.92286613 |
| 68 | nucleotide transmembrane transport (GO:1901679) | 2.88930272 |
| 69 | positive regulation of mitochondrial fission (GO:0090141) | 2.88062449 |
| 70 | ubiquinone biosynthetic process (GO:0006744) | 2.84744270 |
| 71 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.80573499 |
| 72 | iron-sulfur cluster assembly (GO:0016226) | 2.77896276 |
| 73 | metallo-sulfur cluster assembly (GO:0031163) | 2.77896276 |
| 74 | positive regulation of lamellipodium assembly (GO:0010592) | 2.76297586 |
| 75 | signal transduction in response to DNA damage (GO:0042770) | 2.75295666 |
| 76 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.72937149 |
| 77 | GPI anchor biosynthetic process (GO:0006506) | 2.70909072 |
| 78 | chaperone-mediated protein transport (GO:0072321) | 2.68430262 |
| 79 | negative regulation of cation channel activity (GO:2001258) | 2.68039994 |
| 80 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.67404912 |
| 81 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.67404912 |
| 82 | NADH dehydrogenase complex assembly (GO:0010257) | 2.67404912 |
| 83 | response to xenobiotic stimulus (GO:0009410) | 2.66767189 |
| 84 | negative regulation of protein ubiquitination (GO:0031397) | 2.64261884 |
| 85 | regulation of cell cycle arrest (GO:0071156) | 2.63731977 |
| 86 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.63076384 |
| 87 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.63063554 |
| 88 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.62571509 |
| 89 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.61462628 |
| 90 | sulfation (GO:0051923) | 2.60964229 |
| 91 | protein targeting to mitochondrion (GO:0006626) | 2.60018419 |
| 92 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.59970646 |
| 93 | regulation of protein kinase A signaling (GO:0010738) | 2.58571199 |
| 94 | ubiquinone metabolic process (GO:0006743) | 2.57822676 |
| 95 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.57731697 |
| 96 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.57724549 |
| 97 | regulation of ligase activity (GO:0051340) | 2.56331416 |
| 98 | cellular response to exogenous dsRNA (GO:0071360) | 2.54437957 |
| 99 | positive regulation of TOR signaling (GO:0032008) | 2.53337854 |
| 100 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.52851537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 5.87487113 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.24582507 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.20111955 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.81021465 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.49321546 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.41690500 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.17411691 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.97238109 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.71953538 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.70745439 |
| 11 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.69261823 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.68262118 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.64318259 |
| 14 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.58597274 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.55346294 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.43828337 |
| 17 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.38445438 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.35055289 |
| 19 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.29491464 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.25135301 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.14196587 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11200386 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.02969460 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.01749427 |
| 25 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.97484616 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.95312227 |
| 27 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.89031348 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.88115295 |
| 29 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.86869866 |
| 30 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79533320 |
| 31 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.79137554 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.74241500 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.71410494 |
| 34 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.69928340 |
| 35 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.69111270 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68992214 |
| 37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.61151440 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.60727954 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.58313780 |
| 40 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.54264848 |
| 41 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.53848227 |
| 42 | MYB_26560356_Chip-Seq_TH2_Human | 1.50529702 |
| 43 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.49404902 |
| 44 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.49301601 |
| 45 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.43473204 |
| 46 | GATA3_26560356_Chip-Seq_TH2_Human | 1.40933522 |
| 47 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.38306945 |
| 48 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.33403350 |
| 49 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.32617430 |
| 50 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.31898970 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.29766841 |
| 52 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.27412782 |
| 53 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24800873 |
| 54 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.22316826 |
| 55 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.21676115 |
| 56 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.20010556 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19932075 |
| 58 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.18775363 |
| 59 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.17887667 |
| 60 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.17461678 |
| 61 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17014706 |
| 62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.13234676 |
| 63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12198201 |
| 64 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.09754714 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08971622 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08971622 |
| 67 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.08332861 |
| 68 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.07578749 |
| 69 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.05370222 |
| 70 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.05099068 |
| 71 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04526547 |
| 72 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03435940 |
| 73 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03054706 |
| 74 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02734096 |
| 75 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02582312 |
| 76 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.02483524 |
| 77 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01939848 |
| 78 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.01483565 |
| 79 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01183302 |
| 80 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.01002419 |
| 81 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.99579614 |
| 82 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.99011903 |
| 83 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.98012271 |
| 84 | EWS_26573619_Chip-Seq_HEK293_Human | 0.97119234 |
| 85 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.96715934 |
| 86 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.93666995 |
| 87 | ERA_21632823_ChIP-Seq_H3396_Human | 0.89001587 |
| 88 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.88789204 |
| 89 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88279473 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88279473 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88193203 |
| 92 | P300_27268052_Chip-Seq_Bcells_Human | 0.86442385 |
| 93 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85667113 |
| 94 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.85369976 |
| 95 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.84716042 |
| 96 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.84487688 |
| 97 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.83490164 |
| 98 | GATA3_26560356_Chip-Seq_TH1_Human | 0.83287872 |
| 99 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.83166104 |
| 100 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.82246129 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 3.59551088 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.50448922 |
| 3 | MP0005671_abnormal_response_to | 3.09971109 |
| 4 | MP0002166_altered_tumor_susceptibility | 2.82330039 |
| 5 | MP0002102_abnormal_ear_morphology | 2.74289162 |
| 6 | MP0001905_abnormal_dopamine_level | 2.53003207 |
| 7 | MP0009764_decreased_sensitivity_to | 2.50660792 |
| 8 | MP0002006_tumorigenesis | 2.47907941 |
| 9 | MP0000685_abnormal_immune_system | 2.39058595 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.35873689 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 2.35253643 |
| 12 | MP0003724_increased_susceptibility_to | 2.35229666 |
| 13 | MP0009785_altered_susceptibility_to | 2.27637156 |
| 14 | MP0003786_premature_aging | 2.22776709 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 2.17251084 |
| 16 | MP0008875_abnormal_xenobiotic_pharmacok | 2.05883722 |
| 17 | MP0002837_dystrophic_cardiac_calcinosis | 2.02856279 |
| 18 | MP0001542_abnormal_bone_strength | 1.95622508 |
| 19 | MP0005083_abnormal_biliary_tract | 1.86719122 |
| 20 | MP0003191_abnormal_cellular_cholesterol | 1.83800722 |
| 21 | MP0006035_abnormal_mitochondrial_morpho | 1.80451631 |
| 22 | MP0008872_abnormal_physiological_respon | 1.73356692 |
| 23 | MP0003646_muscle_fatigue | 1.70557774 |
| 24 | MP0003123_paternal_imprinting | 1.70436537 |
| 25 | MP0004885_abnormal_endolymph | 1.62026698 |
| 26 | MP0001800_abnormal_humoral_immune | 1.61204032 |
| 27 | MP0001968_abnormal_touch/_nociception | 1.55669561 |
| 28 | MP0002723_abnormal_immune_serum | 1.52580184 |
| 29 | MP0002452_abnormal_antigen_presenting | 1.52202544 |
| 30 | MP0003075_altered_response_to | 1.52073072 |
| 31 | MP0005000_abnormal_immune_tolerance | 1.47185271 |
| 32 | MP0001853_heart_inflammation | 1.43310236 |
| 33 | MP0001819_abnormal_immune_cell | 1.41777418 |
| 34 | MP0002420_abnormal_adaptive_immunity | 1.40100905 |
| 35 | MP0005025_abnormal_response_to | 1.39748480 |
| 36 | MP0002138_abnormal_hepatobiliary_system | 1.37977665 |
| 37 | MP0002736_abnormal_nociception_after | 1.37082475 |
| 38 | MP0006036_abnormal_mitochondrial_physio | 1.36683026 |
| 39 | MP0009697_abnormal_copulation | 1.32219641 |
| 40 | MP0003195_calcinosis | 1.30793312 |
| 41 | MP0003183_abnormal_peptide_metabolism | 1.30319134 |
| 42 | MP0001529_abnormal_vocalization | 1.27512826 |
| 43 | MP0005464_abnormal_platelet_physiology | 1.27460182 |
| 44 | MP0001188_hyperpigmentation | 1.21610694 |
| 45 | MP0008775_abnormal_heart_ventricle | 1.20642135 |
| 46 | MP0001790_abnormal_immune_system | 1.20098246 |
| 47 | MP0005387_immune_system_phenotype | 1.20098246 |
| 48 | MP0000343_altered_response_to | 1.18957473 |
| 49 | MP0005167_abnormal_blood-brain_barrier | 1.18897895 |
| 50 | MP0003866_abnormal_defecation | 1.12854009 |
| 51 | MP0003011_delayed_dark_adaptation | 1.12105647 |
| 52 | MP0005646_abnormal_pituitary_gland | 1.10708507 |
| 53 | MP0005165_increased_susceptibility_to | 1.09674280 |
| 54 | MP0008058_abnormal_DNA_repair | 1.09649316 |
| 55 | MP0003436_decreased_susceptibility_to | 1.09009336 |
| 56 | MP0009780_abnormal_chondrocyte_physiolo | 1.08805784 |
| 57 | MP0002095_abnormal_skin_pigmentation | 1.05651404 |
| 58 | MP0008260_abnormal_autophagy | 1.04040517 |
| 59 | MP0000858_altered_metastatic_potential | 1.03679443 |
| 60 | MP0002272_abnormal_nervous_system | 1.03521597 |
| 61 | MP0000751_myopathy | 1.02304425 |
| 62 | MP0005253_abnormal_eye_physiology | 1.02165155 |
| 63 | MP0003950_abnormal_plasma_membrane | 1.01691588 |
| 64 | MP0001243_abnormal_dermal_layer | 1.01660242 |
| 65 | MP0002419_abnormal_innate_immunity | 1.00688110 |
| 66 | MP0002332_abnormal_exercise_endurance | 1.00664692 |
| 67 | MP0004145_abnormal_muscle_electrophysio | 0.98218090 |
| 68 | MP0000749_muscle_degeneration | 0.96840812 |
| 69 | MP0002722_abnormal_immune_system | 0.96161249 |
| 70 | MP0000689_abnormal_spleen_morphology | 0.95601812 |
| 71 | MP0000358_abnormal_cell_content/ | 0.94898989 |
| 72 | MP0000716_abnormal_immune_system | 0.94801134 |
| 73 | MP0008877_abnormal_DNA_methylation | 0.94229963 |
| 74 | MP0000613_abnormal_salivary_gland | 0.93888551 |
| 75 | MP0002282_abnormal_trachea_morphology | 0.92338738 |
| 76 | MP0000516_abnormal_urinary_system | 0.91702071 |
| 77 | MP0005367_renal/urinary_system_phenotyp | 0.91702071 |
| 78 | MP0000465_gastrointestinal_hemorrhage | 0.91497418 |
| 79 | MP0005389_reproductive_system_phenotype | 0.90264029 |
| 80 | MP0003638_abnormal_response/metabolism_ | 0.87566081 |
| 81 | MP0008007_abnormal_cellular_replicative | 0.86589535 |
| 82 | MP0003186_abnormal_redox_activity | 0.85770957 |
| 83 | MP0003880_abnormal_central_pattern | 0.85676162 |
| 84 | MP0005166_decreased_susceptibility_to | 0.85629778 |
| 85 | MP0002933_joint_inflammation | 0.85144498 |
| 86 | MP0000372_irregular_coat_pigmentation | 0.84609272 |
| 87 | MP0001845_abnormal_inflammatory_respons | 0.84108680 |
| 88 | MP0003718_maternal_effect | 0.81032116 |
| 89 | MP0000639_abnormal_adrenal_gland | 0.80910292 |
| 90 | MP0002429_abnormal_blood_cell | 0.80675697 |
| 91 | MP0003806_abnormal_nucleotide_metabolis | 0.80134340 |
| 92 | MP0010155_abnormal_intestine_physiology | 0.79302201 |
| 93 | MP0009763_increased_sensitivity_to | 0.78837698 |
| 94 | MP0002398_abnormal_bone_marrow | 0.78730729 |
| 95 | MP0001533_abnormal_skeleton_physiology | 0.78395037 |
| 96 | MP0009333_abnormal_splenocyte_physiolog | 0.77329617 |
| 97 | MP0005410_abnormal_fertilization | 0.76561130 |
| 98 | MP0002177_abnormal_outer_ear | 0.76349564 |
| 99 | MP0001919_abnormal_reproductive_system | 0.75721162 |
| 100 | MP0005636_abnormal_mineral_homeostasis | 0.75642716 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.88261933 |
| 2 | Hepatocellular necrosis (HP:0001404) | 4.40158401 |
| 3 | Hepatic necrosis (HP:0002605) | 4.34694522 |
| 4 | IgG deficiency (HP:0004315) | 4.26440409 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.86781354 |
| 6 | Increased CSF lactate (HP:0002490) | 3.49907795 |
| 7 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.47292254 |
| 8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.47292254 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.46601322 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.27738074 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.26510224 |
| 12 | Hyperalaninemia (HP:0003348) | 3.15816127 |
| 13 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.15816127 |
| 14 | Abnormality of alanine metabolism (HP:0010916) | 3.15816127 |
| 15 | Short tibia (HP:0005736) | 3.03269196 |
| 16 | Type I transferrin isoform profile (HP:0003642) | 2.99195413 |
| 17 | Generalized aminoaciduria (HP:0002909) | 2.98200045 |
| 18 | Increased serum lactate (HP:0002151) | 2.96305991 |
| 19 | Acute encephalopathy (HP:0006846) | 2.95369603 |
| 20 | Abolished electroretinogram (ERG) (HP:0000550) | 2.94089628 |
| 21 | Lactic acidosis (HP:0003128) | 2.88749783 |
| 22 | Increased IgM level (HP:0003496) | 2.85789759 |
| 23 | Cerebral palsy (HP:0100021) | 2.84471004 |
| 24 | Progressive macrocephaly (HP:0004481) | 2.77759275 |
| 25 | Conjunctival hamartoma (HP:0100780) | 2.77347229 |
| 26 | Adrenal hypoplasia (HP:0000835) | 2.74586726 |
| 27 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.66663784 |
| 28 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.63964577 |
| 29 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.62973961 |
| 30 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.56370508 |
| 31 | Glucose intolerance (HP:0000833) | 2.51053716 |
| 32 | Abnormality of the prostate (HP:0008775) | 2.51050739 |
| 33 | Reduced antithrombin III activity (HP:0001976) | 2.47385020 |
| 34 | Facial diplegia (HP:0001349) | 2.40832772 |
| 35 | Stomatitis (HP:0010280) | 2.40070926 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.38688846 |
| 37 | Hypoproteinemia (HP:0003075) | 2.34241612 |
| 38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.33507296 |
| 39 | Prostate neoplasm (HP:0100787) | 2.29524113 |
| 40 | Fibular aplasia (HP:0002990) | 2.29397057 |
| 41 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.25089985 |
| 42 | Dicarboxylic aciduria (HP:0003215) | 2.25089985 |
| 43 | Respiratory failure (HP:0002878) | 2.20139241 |
| 44 | Cerebral edema (HP:0002181) | 2.19443301 |
| 45 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.18109843 |
| 46 | Decreased central vision (HP:0007663) | 2.14481357 |
| 47 | Methylmalonic acidemia (HP:0002912) | 2.11662128 |
| 48 | Microretrognathia (HP:0000308) | 2.11227900 |
| 49 | Abnormality of midbrain morphology (HP:0002418) | 2.10520726 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.10520726 |
| 51 | Pulmonary fibrosis (HP:0002206) | 2.09536256 |
| 52 | Emotional lability (HP:0000712) | 2.09103482 |
| 53 | Increased hepatocellular lipid droplets (HP:0006565) | 2.08958074 |
| 54 | Rough bone trabeculation (HP:0100670) | 2.06013728 |
| 55 | Myositis (HP:0100614) | 2.04914521 |
| 56 | Exercise intolerance (HP:0003546) | 2.03978790 |
| 57 | Oral leukoplakia (HP:0002745) | 2.02179369 |
| 58 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.01303361 |
| 59 | Abnormal protein glycosylation (HP:0012346) | 2.01303361 |
| 60 | Abnormal glycosylation (HP:0012345) | 2.01303361 |
| 61 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.01303361 |
| 62 | Attenuation of retinal blood vessels (HP:0007843) | 1.99907318 |
| 63 | Vertebral compression fractures (HP:0002953) | 1.99682903 |
| 64 | Erythema (HP:0010783) | 1.95943648 |
| 65 | Optic disc pallor (HP:0000543) | 1.95736935 |
| 66 | Acute hepatic failure (HP:0006554) | 1.95333614 |
| 67 | Nausea (HP:0002018) | 1.94038996 |
| 68 | Pancytopenia (HP:0001876) | 1.93338348 |
| 69 | CNS demyelination (HP:0007305) | 1.91396329 |
| 70 | Renal Fanconi syndrome (HP:0001994) | 1.90775966 |
| 71 | Methylmalonic aciduria (HP:0012120) | 1.89728403 |
| 72 | Severe combined immunodeficiency (HP:0004430) | 1.89342301 |
| 73 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.89067563 |
| 74 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.88554748 |
| 75 | Pustule (HP:0200039) | 1.84724458 |
| 76 | Palpitations (HP:0001962) | 1.84605891 |
| 77 | Rhabdomyolysis (HP:0003201) | 1.83592462 |
| 78 | Palpebral edema (HP:0100540) | 1.83556948 |
| 79 | Spastic paraparesis (HP:0002313) | 1.83180591 |
| 80 | Aplastic anemia (HP:0001915) | 1.82780507 |
| 81 | Hypoplastic pelvis (HP:0008839) | 1.81805974 |
| 82 | Entropion (HP:0000621) | 1.80942628 |
| 83 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.80874573 |
| 84 | Absent/shortened dynein arms (HP:0200106) | 1.80874573 |
| 85 | Congenital stationary night blindness (HP:0007642) | 1.80681660 |
| 86 | Severe visual impairment (HP:0001141) | 1.80626699 |
| 87 | Sparse eyelashes (HP:0000653) | 1.79500677 |
| 88 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.78644049 |
| 89 | Lipid accumulation in hepatocytes (HP:0006561) | 1.75870106 |
| 90 | Progressive inability to walk (HP:0002505) | 1.75060229 |
| 91 | IgM deficiency (HP:0002850) | 1.74242151 |
| 92 | Chronic sinusitis (HP:0011109) | 1.74164265 |
| 93 | Bone cyst (HP:0012062) | 1.73560685 |
| 94 | Growth hormone excess (HP:0000845) | 1.73003352 |
| 95 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.70410620 |
| 96 | Short femoral neck (HP:0100864) | 1.69279992 |
| 97 | Exertional dyspnea (HP:0002875) | 1.69090120 |
| 98 | Amyotrophic lateral sclerosis (HP:0007354) | 1.68348377 |
| 99 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.66143250 |
| 100 | Lethargy (HP:0001254) | 1.65148590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.79151762 |
| 2 | VRK2 | 4.57215146 |
| 3 | TESK1 | 4.29070871 |
| 4 | LIMK1 | 3.74180846 |
| 5 | KDR | 3.53130807 |
| 6 | TIE1 | 3.25999090 |
| 7 | TAOK3 | 2.49553613 |
| 8 | NME2 | 2.36450588 |
| 9 | MAP3K12 | 2.30922380 |
| 10 | BCKDK | 2.29789892 |
| 11 | CSNK1G3 | 2.09686023 |
| 12 | MAP4K2 | 2.01716420 |
| 13 | CSNK1A1L | 1.97424586 |
| 14 | TLK1 | 1.82729453 |
| 15 | VRK1 | 1.73540459 |
| 16 | DAPK1 | 1.72394421 |
| 17 | BCR | 1.71167271 |
| 18 | TXK | 1.70937023 |
| 19 | PIM2 | 1.66871160 |
| 20 | GRK1 | 1.65161467 |
| 21 | BUB1 | 1.60273630 |
| 22 | CSNK1G2 | 1.57601764 |
| 23 | ERBB3 | 1.55059101 |
| 24 | CSNK1G1 | 1.54296361 |
| 25 | ADRBK2 | 1.40628591 |
| 26 | NUAK1 | 1.39102981 |
| 27 | CDK8 | 1.34079451 |
| 28 | MAPKAPK3 | 1.28353614 |
| 29 | STK16 | 1.22834832 |
| 30 | CCNB1 | 1.20611059 |
| 31 | EPHA2 | 1.17401757 |
| 32 | NEK1 | 1.14599153 |
| 33 | SRPK1 | 1.13350020 |
| 34 | MYLK | 1.10632773 |
| 35 | ARAF | 1.03306789 |
| 36 | ZAK | 0.99437719 |
| 37 | MAP2K7 | 0.92820389 |
| 38 | TEC | 0.92196968 |
| 39 | TRIM28 | 0.87729309 |
| 40 | RPS6KA4 | 0.85402083 |
| 41 | CSF1R | 0.83715139 |
| 42 | RPS6KA5 | 0.82620831 |
| 43 | PHKG1 | 0.81330162 |
| 44 | PHKG2 | 0.81330162 |
| 45 | TBK1 | 0.79915084 |
| 46 | SCYL2 | 0.79778156 |
| 47 | MAP4K1 | 0.75657985 |
| 48 | ZAP70 | 0.72139630 |
| 49 | PINK1 | 0.71320845 |
| 50 | GRK5 | 0.70193387 |
| 51 | LMTK2 | 0.69710481 |
| 52 | PTK2B | 0.64205036 |
| 53 | KIT | 0.55102269 |
| 54 | MST1R | 0.54280866 |
| 55 | WNK4 | 0.53761444 |
| 56 | IKBKB | 0.52938415 |
| 57 | ITK | 0.50907503 |
| 58 | FLT3 | 0.50740810 |
| 59 | IRAK3 | 0.50266548 |
| 60 | GRK6 | 0.49572288 |
| 61 | DAPK3 | 0.48470654 |
| 62 | SIK3 | 0.48086833 |
| 63 | WNK3 | 0.46540485 |
| 64 | PAK1 | 0.45991721 |
| 65 | IKBKE | 0.45691504 |
| 66 | MAPK13 | 0.44893448 |
| 67 | SYK | 0.44154823 |
| 68 | ABL2 | 0.43967867 |
| 69 | EIF2AK1 | 0.43954904 |
| 70 | MST4 | 0.43217228 |
| 71 | MINK1 | 0.42640607 |
| 72 | EIF2AK2 | 0.42154952 |
| 73 | PRKCE | 0.40985955 |
| 74 | DYRK2 | 0.38684877 |
| 75 | BLK | 0.37932298 |
| 76 | INSRR | 0.37601575 |
| 77 | DAPK2 | 0.36645284 |
| 78 | AURKA | 0.36433426 |
| 79 | MAP3K14 | 0.36341647 |
| 80 | EGFR | 0.34838114 |
| 81 | TAF1 | 0.34631497 |
| 82 | PLK3 | 0.34208735 |
| 83 | EIF2AK3 | 0.33955123 |
| 84 | CSNK1A1 | 0.33819370 |
| 85 | PLK2 | 0.33451946 |
| 86 | TNK2 | 0.32828866 |
| 87 | CSNK2A1 | 0.32420069 |
| 88 | PRKCI | 0.31824406 |
| 89 | IGF1R | 0.31487869 |
| 90 | CAMK2G | 0.31044512 |
| 91 | BMPR2 | 0.29334596 |
| 92 | ADRBK1 | 0.28941396 |
| 93 | MAP3K11 | 0.28310414 |
| 94 | LCK | 0.26937227 |
| 95 | ILK | 0.26900943 |
| 96 | MAP3K4 | 0.26853965 |
| 97 | MAPKAPK2 | 0.26788871 |
| 98 | PRKCQ | 0.26783527 |
| 99 | OXSR1 | 0.26513332 |
| 100 | PIM1 | 0.26230874 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.81959195 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.60905297 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 2.93623728 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.45709071 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.39123754 |
| 6 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.30699050 |
| 7 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.23021363 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.21182228 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.21177619 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.14940801 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.07631848 |
| 12 | Allograft rejection_Homo sapiens_hsa05330 | 2.01162813 |
| 13 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.00253152 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.99201429 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.98442831 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.96368399 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.96034020 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.92023728 |
| 19 | DNA replication_Homo sapiens_hsa03030 | 1.65545243 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.46598020 |
| 21 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.42870270 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.42462312 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.40566419 |
| 24 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.39212066 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.38704413 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.38214546 |
| 27 | Shigellosis_Homo sapiens_hsa05131 | 1.33454784 |
| 28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.31874547 |
| 29 | Spliceosome_Homo sapiens_hsa03040 | 1.26845958 |
| 30 | Viral myocarditis_Homo sapiens_hsa05416 | 1.24559792 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.18099691 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.16403069 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.10075033 |
| 34 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.09683016 |
| 35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.04275957 |
| 36 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.03591627 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.03321550 |
| 38 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.01843538 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 0.99162194 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.98971982 |
| 41 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.97519108 |
| 42 | Phototransduction_Homo sapiens_hsa04744 | 0.92759545 |
| 43 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.92243913 |
| 44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.91053891 |
| 45 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87325621 |
| 46 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.86604724 |
| 47 | Base excision repair_Homo sapiens_hsa03410 | 0.85548587 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.83480677 |
| 49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.82426469 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.81374776 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.80887045 |
| 52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.80183503 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.79286907 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78835103 |
| 55 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78334940 |
| 56 | Ribosome_Homo sapiens_hsa03010 | 0.76851721 |
| 57 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.75314186 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.75097719 |
| 59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.74188565 |
| 60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.73011186 |
| 61 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.72183743 |
| 62 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.71759340 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.71013865 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61957356 |
| 65 | Basal transcription factors_Homo sapiens_hsa03022 | 0.61035860 |
| 66 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.60194230 |
| 67 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.59583879 |
| 68 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.59555612 |
| 69 | Salivary secretion_Homo sapiens_hsa04970 | 0.58866964 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57256777 |
| 71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56163154 |
| 72 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56074941 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.54113144 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53820307 |
| 75 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.51802319 |
| 76 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.50415972 |
| 77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.49703233 |
| 78 | Salmonella infection_Homo sapiens_hsa05132 | 0.49443899 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.49319037 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48720422 |
| 81 | Carbon metabolism_Homo sapiens_hsa01200 | 0.48522777 |
| 82 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.47795826 |
| 83 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.47588464 |
| 84 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.47292709 |
| 85 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.45063149 |
| 86 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.43934028 |
| 87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.43287887 |
| 88 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.40666810 |
| 89 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.39910764 |
| 90 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.39439620 |
| 91 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.38330753 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38259845 |
| 93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.37353407 |
| 94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35452306 |
| 95 | Measles_Homo sapiens_hsa05162 | 0.32752447 |
| 96 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.32156049 |
| 97 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.32001385 |
| 98 | Legionellosis_Homo sapiens_hsa05134 | 0.31495731 |
| 99 | Endocytosis_Homo sapiens_hsa04144 | 0.26876500 |
| 100 | Pertussis_Homo sapiens_hsa05133 | 0.26491323 |

