CFP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.92284598
2detection of other organism (GO:0098543)5.57255921
3response to peptidoglycan (GO:0032494)5.57047131
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.48502197
5positive regulation by organism of defense response of other organism involved in symbiotic interact5.48502197
6modulation by symbiont of host immune response (GO:0052553)5.48502197
7positive regulation by symbiont of host defense response (GO:0052509)5.48502197
8modulation by symbiont of host defense response (GO:0052031)5.48502197
9modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.48502197
10detection of bacterium (GO:0016045)5.39506194
11production of molecular mediator involved in inflammatory response (GO:0002532)5.34381864
12respiratory burst (GO:0045730)4.98716675
13cellular extravasation (GO:0045123)4.76473589
14lipoxygenase pathway (GO:0019372)4.60726219
15immunoglobulin mediated immune response (GO:0016064)4.60042485
16regulation of interferon-beta biosynthetic process (GO:0045357)4.57962058
17detection of external biotic stimulus (GO:0098581)4.55764276
18antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.46998230
19macrophage activation involved in immune response (GO:0002281)4.44715427
20positive regulation of interferon-alpha production (GO:0032727)4.31921973
21negative regulation of lymphocyte mediated immunity (GO:0002707)4.29732096
22regulation of gamma-delta T cell activation (GO:0046643)4.28387461
23leukocyte migration involved in inflammatory response (GO:0002523)4.28017362
24regulation of B cell receptor signaling pathway (GO:0050855)4.17576577
25regulation of interferon-alpha production (GO:0032647)4.08383822
26positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.07991922
27detection of biotic stimulus (GO:0009595)4.07804052
28positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.03725264
29positive regulation of antigen processing and presentation (GO:0002579)3.96891779
30granulocyte activation (GO:0036230)3.95801339
31neutrophil activation (GO:0042119)3.93759812
32hydrogen peroxide biosynthetic process (GO:0050665)3.89523003
33detection of molecule of bacterial origin (GO:0032490)3.84825895
34positive regulation of mast cell activation (GO:0033005)3.84104681
35regulation of integrin activation (GO:0033623)3.83676379
36negative regulation of T cell mediated immunity (GO:0002710)3.81835605
37lymphocyte chemotaxis (GO:0048247)3.80719330
38negative regulation of leukocyte mediated immunity (GO:0002704)3.80379519
39regulation of dendritic cell antigen processing and presentation (GO:0002604)3.73611187
40regulation of apoptotic cell clearance (GO:2000425)3.73357519
41myeloid cell activation involved in immune response (GO:0002275)3.69690988
42leukotriene metabolic process (GO:0006691)3.68712930
43regulation of mononuclear cell migration (GO:0071675)3.65571367
44response to host immune response (GO:0052572)3.65266721
45response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.65266721
46regulation of mast cell degranulation (GO:0043304)3.64994144
47reactive oxygen species biosynthetic process (GO:1903409)3.61693688
48positive regulation of mast cell activation involved in immune response (GO:0033008)3.60603998
49positive regulation of mast cell degranulation (GO:0043306)3.60603998
50antigen processing and presentation of endogenous antigen (GO:0019883)3.60024265
51regulation of gamma-delta T cell differentiation (GO:0045586)3.58873837
52response to interleukin-15 (GO:0070672)3.58029673
53negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.55795968
54regulation of tolerance induction (GO:0002643)3.55482973
55antigen processing and presentation via MHC class Ib (GO:0002475)3.55162623
56positive regulation of monocyte chemotaxis (GO:0090026)3.53831702
57regulation of T cell tolerance induction (GO:0002664)3.51771271
58superoxide anion generation (GO:0042554)3.51770624
59lipopolysaccharide-mediated signaling pathway (GO:0031663)3.50718710
60negative regulation of erythrocyte differentiation (GO:0045647)3.47548600
61response to muramyl dipeptide (GO:0032495)3.44670495
62germinal center formation (GO:0002467)3.44380035
63regulation of mast cell activation (GO:0033003)3.39756824
64regulation of antigen processing and presentation (GO:0002577)3.39613468
65positive regulation of lymphocyte migration (GO:2000403)3.39531181
66mannose metabolic process (GO:0006013)3.39503938
67regulation of mast cell activation involved in immune response (GO:0033006)3.39115342
68macrophage activation (GO:0042116)3.39059544
69neutrophil mediated immunity (GO:0002446)3.37911504
70regulation of T cell chemotaxis (GO:0010819)3.37208755
71positive regulation of T cell chemotaxis (GO:0010820)3.37208755
72negative regulation of cell killing (GO:0031342)3.36848249
73negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.36848249
74negative regulation of interleukin-12 production (GO:0032695)3.35914190
75B cell receptor signaling pathway (GO:0050853)3.35005846
76leukocyte degranulation (GO:0043299)3.33913147
77regulation of B cell differentiation (GO:0045577)3.33735416
78B cell mediated immunity (GO:0019724)3.32489719
79positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.30510306
80response to host defenses (GO:0052200)3.28740241
81response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.28740241
82response to host (GO:0075136)3.28740241
83neutrophil chemotaxis (GO:0030593)3.27249428
84negative regulation of phagocytosis (GO:0050765)3.26907356
85apoptotic cell clearance (GO:0043277)3.26725944
86pinocytosis (GO:0006907)3.26709977
87myeloid leukocyte mediated immunity (GO:0002444)3.23176368
88regulation of cholesterol storage (GO:0010885)3.22917901
89regulation of lymphocyte chemotaxis (GO:1901623)3.22550671
90positive regulation of T cell migration (GO:2000406)3.21757050
91cellular response to interleukin-15 (GO:0071350)3.21626833
92positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610813.20534488
93negative regulation of granulocyte differentiation (GO:0030853)3.20141138
94regulation of leukocyte degranulation (GO:0043300)3.19359653
95regulation of myeloid leukocyte mediated immunity (GO:0002886)3.18801754
96neutrophil migration (GO:1990266)3.17764554
97regulation of T cell migration (GO:2000404)3.16463568
98microglial cell activation (GO:0001774)3.16350176
99regulation of lymphocyte migration (GO:2000401)3.14140792
100regulation of regulated secretory pathway (GO:1903305)3.13724537
101positive regulation of cellular amide metabolic process (GO:0034250)3.13623222
102negative regulation of interleukin-6 production (GO:0032715)3.11190023
103defense response to protozoan (GO:0042832)3.10384286
104leukocyte mediated cytotoxicity (GO:0001909)3.10080774
105positive thymic T cell selection (GO:0045059)3.08763814
106leukocyte aggregation (GO:0070486)3.08359613
107activated T cell proliferation (GO:0050798)3.07757525
108Arp2/3 complex-mediated actin nucleation (GO:0034314)3.06873308
109positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)3.05976179
110negative thymic T cell selection (GO:0045060)3.04829760
111positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.04285105
112regulation of T-helper 2 cell differentiation (GO:0045628)3.03959046
113regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.03595849
114T cell migration (GO:0072678)3.03341842
115negative regulation of cytokine production involved in immune response (GO:0002719)3.03277900
116positive regulation of leukocyte degranulation (GO:0043302)3.00610287
117interferon-gamma-mediated signaling pathway (GO:0060333)2.98444117
118regulation of alpha-beta T cell proliferation (GO:0046640)2.98168549
119positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.97688566
120regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.97658956
121granulocyte chemotaxis (GO:0071621)2.96432455
122regulation of macrophage chemotaxis (GO:0010758)2.96420171
123positive regulation of chemokine biosynthetic process (GO:0045080)2.95623367
124positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.95504012
125positive regulation of gamma-delta T cell activation (GO:0046645)2.95155568
126positive regulation of interferon-beta production (GO:0032728)2.95114920
127cellular response to type I interferon (GO:0071357)2.94488201
128type I interferon signaling pathway (GO:0060337)2.94488201
129negative T cell selection (GO:0043383)2.94389164
130antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.94301504
131antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.94301504
132positive regulation of B cell differentiation (GO:0045579)2.93535199
133negative regulation of type 2 immune response (GO:0002829)2.92540617
134regulation of T cell mediated cytotoxicity (GO:0001914)2.92151373
135response to type I interferon (GO:0034340)2.92021291
136regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.92016661
137negative regulation of innate immune response (GO:0045824)2.91644956
138regulation of monocyte chemotaxis (GO:0090025)2.91245702
139myeloid leukocyte activation (GO:0002274)2.90932116
140positive regulation of tolerance induction (GO:0002645)2.90854775
141response to protozoan (GO:0001562)2.90435398
142tolerance induction (GO:0002507)2.88965819

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human8.00690637
2IRF8_21731497_ChIP-ChIP_J774_Mouse7.16258975
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.94783548
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.69585173
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.34496506
6NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.77421422
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.66385237
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.60760250
9Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.53010308
10MYB_21317192_ChIP-Seq_ERMYB_Mouse3.22970737
11NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.97056976
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.92725147
13* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.84456284
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.76343593
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.61011414
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.55776232
17RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.54884678
18BRD4_27068464_Chip-Seq_AML-cells_Mouse2.44958194
19* SPI1_23547873_ChIP-Seq_NB4_Human2.39226828
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.31385043
21RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.14124285
22STAT4_19710469_ChIP-ChIP_TH1__Mouse2.13821406
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.02437854
24PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.97811402
25VDR_24763502_ChIP-Seq_THP-1_Human1.94735064
26SCL_19346495_ChIP-Seq_HPC-7_Human1.90151023
27* SPI1_23127762_ChIP-Seq_K562_Human1.88147654
28* RUNX1_22412390_ChIP-Seq_EML_Mouse1.83222119
29CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.81844213
30PU_27001747_Chip-Seq_BMDM_Mouse1.76235318
31CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.73186185
32VDR_21846776_ChIP-Seq_THP-1_Human1.72708460
33MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.68404773
34STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.66857059
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.66660355
36MYB_26560356_Chip-Seq_TH2_Human1.63610450
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62462708
38PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.60077204
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57875943
40RUNX_20019798_ChIP-Seq_JUKART_Human1.56679358
41VDR_24787735_ChIP-Seq_THP-1_Human1.54665646
42KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.53629689
43MAF_26560356_Chip-Seq_TH1_Human1.52078090
44CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.51389018
45LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.48579443
46SMAD_19615063_ChIP-ChIP_OVARY_Human1.48093725
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.47302408
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.47048543
49CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.46446788
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39934654
51ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.36596468
52STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36568168
53FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35672509
54PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.35640224
55PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.33533054
56LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.32857762
57E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.32458085
58ELF1_17652178_ChIP-ChIP_JURKAT_Human1.27662598
59MYB_26560356_Chip-Seq_TH1_Human1.24736670
60SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19324585
61GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.15057308
62KDM2B_26808549_Chip-Seq_JURKAT_Human1.14985232
63NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.14176758
64VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.13703070
65UTX_26944678_Chip-Seq_JUKART_Human1.09203873
66GATA3_26560356_Chip-Seq_TH2_Human1.08839711
67GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08122764
68RXR_22158963_ChIP-Seq_LIVER_Mouse1.07216066
69TCF7_22412390_ChIP-Seq_EML_Mouse1.04190880
70SPI1_20517297_ChIP-Seq_HL60_Human1.03708559
71IKZF1_21737484_ChIP-ChIP_HCT116_Human1.03133698
72TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02644145
73GATA3_27048872_Chip-Seq_THYMUS_Human1.02536910
74GATA1_22025678_ChIP-Seq_K562_Human1.02509836
75CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.02507316
76GATA2_21666600_ChIP-Seq_HMVEC_Human1.02262769
77GATA1_19941827_ChIP-Seq_MEL_Mouse1.01606551
78PPARA_22158963_ChIP-Seq_LIVER_Mouse1.01095073
79STAT6_21828071_ChIP-Seq_BEAS2B_Human0.99307897
80RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97257846
81SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96095721
82GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95769501
83EGR1_23403033_ChIP-Seq_LIVER_Mouse0.95085813
84RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.94812933
85MYC_22102868_ChIP-Seq_BL_Human0.94684303
86NCOR1_26117541_ChIP-Seq_K562_Human0.91693194
87ELK3_25401928_ChIP-Seq_HUVEC_Human0.90896091
88EGR1_19032775_ChIP-ChIP_M12_Human0.90794550
89SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90632100
90LXR_22158963_ChIP-Seq_LIVER_Mouse0.89288609
91CTCF_27219007_Chip-Seq_ERYTHROID_Human0.88060464
92CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.87177122
93LXR_22292898_ChIP-Seq_THP-1_Human0.87133046
94E2F7_22180533_ChIP-Seq_HELA_Human0.85639845
95TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.85038898
96TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84323995
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83546869
98TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.82734924
99ELF1_20517297_ChIP-Seq_JURKAT_Human0.82106552
100MAF_26560356_Chip-Seq_TH2_Human0.81592950
101GATA2_19941826_ChIP-Seq_K562_Human0.80894507
102KDM2B_26808549_Chip-Seq_SUP-B15_Human0.78228045
103RARG_19884340_ChIP-ChIP_MEFs_Mouse0.76594288
104GATA1_19941826_ChIP-Seq_K562_Human0.74131573
105PU.1_20513432_ChIP-Seq_Bcells_Mouse0.72653648
106GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71820467
107TFEB_21752829_ChIP-Seq_HELA_Human0.71795372
108GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71278339
109CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.69307043
110KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.67603566
111KDM2B_26808549_Chip-Seq_DND41_Human0.67337128
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.64755187
113BCL6_27268052_Chip-Seq_Bcells_Human0.60531717
114CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.60120334
115BCOR_27268052_Chip-Seq_Bcells_Human0.58898714

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.61105896
2* MP0003436_decreased_susceptibility_to3.94330155
3MP0005058_abnormal_lysosome_morphology3.76446068
4MP0002148_abnormal_hypersensitivity_rea3.71649376
5MP0009785_altered_susceptibility_to3.47475411
6* MP0002419_abnormal_innate_immunity3.47080284
7MP0003303_peritoneal_inflammation3.35062093
8* MP0005000_abnormal_immune_tolerance3.23113877
9* MP0005025_abnormal_response_to3.13868337
10MP0005387_immune_system_phenotype3.00984289
11MP0001790_abnormal_immune_system3.00984289
12MP0003724_increased_susceptibility_to2.88188760
13MP0006082_CNS_inflammation2.74802433
14MP0000685_abnormal_immune_system2.74169751
15MP0002452_abnormal_antigen_presenting2.68591688
16* MP0001800_abnormal_humoral_immune2.54094839
17MP0002723_abnormal_immune_serum2.41958454
18MP0009840_abnormal_foam_cell2.32677595
19MP0005464_abnormal_platelet_physiology2.30249786
20MP0001819_abnormal_immune_cell2.24844920
21MP0002420_abnormal_adaptive_immunity2.24123912
22MP0003172_abnormal_lysosome_physiology2.23728493
23MP0005671_abnormal_response_to2.22934115
24* MP0001533_abnormal_skeleton_physiology2.20138217
25MP0004510_myositis2.17256062
26MP0003763_abnormal_thymus_physiology2.10107054
27MP0002405_respiratory_system_inflammati2.03141593
28MP0002132_abnormal_respiratory_system2.00021212
29MP0003075_altered_response_to1.97559197
30MP0001845_abnormal_inflammatory_respons1.96994026
31MP0003191_abnormal_cellular_cholesterol1.96056260
32MP0009333_abnormal_splenocyte_physiolog1.93573695
33MP0001853_heart_inflammation1.91791532
34MP0000343_altered_response_to1.89306368
35MP0004947_skin_inflammation1.88267678
36MP0008469_abnormal_protein_level1.72444007
37MP0000604_amyloidosis1.69796744
38MP0009764_decreased_sensitivity_to1.62388048
39MP0000716_abnormal_immune_system1.61524999
40MP0003690_abnormal_glial_cell1.61024404
41MP0005310_abnormal_salivary_gland1.57790109
42MP0010155_abnormal_intestine_physiology1.56824446
43MP0003448_altered_tumor_morphology1.56537120
44MP0003866_abnormal_defecation1.55782482
45MP0009278_abnormal_bone_marrow1.51778561
46MP0002398_abnormal_bone_marrow1.45421972
47MP0002006_tumorigenesis1.42957974
48MP0000703_abnormal_thymus_morphology1.42381738
49MP0000689_abnormal_spleen_morphology1.40965590
50MP0005166_decreased_susceptibility_to1.35747288
51MP0003300_gastrointestinal_ulcer1.35744354
52MP0002429_abnormal_blood_cell1.30693113
53MP0005451_abnormal_body_composition1.26274626
54MP0004381_abnormal_hair_follicle1.26224596
55MP0003183_abnormal_peptide_metabolism1.24415605
56MP0002998_abnormal_bone_remodeling1.22666135
57MP0002722_abnormal_immune_system1.22031766
58MP0005397_hematopoietic_system_phenotyp1.21042450
59MP0001545_abnormal_hematopoietic_system1.21042450
60MP0000858_altered_metastatic_potential1.19980364
61MP0002166_altered_tumor_susceptibility1.19959564
62MP0001851_eye_inflammation1.19321983
63* MP0009763_increased_sensitivity_to1.10501012
64MP0004782_abnormal_surfactant_physiolog1.10344337
65MP0000569_abnormal_digit_pigmentation1.09431222
66MP0002933_joint_inflammation1.06015379
67MP0003806_abnormal_nucleotide_metabolis1.04765035
68MP0005174_abnormal_tail_pigmentation1.02875504
69MP0003656_abnormal_erythrocyte_physiolo1.02850069
70MP0001986_abnormal_taste_sensitivity1.01250939
71* MP0005390_skeleton_phenotype1.01147875
72MP0003828_pulmonary_edema1.00498521
73MP0000465_gastrointestinal_hemorrhage0.99469581
74MP0002138_abnormal_hepatobiliary_system0.98578931
75MP0003566_abnormal_cell_adhesion0.98208444
76MP0010307_abnormal_tumor_latency0.97897394
77MP0000249_abnormal_blood_vessel0.95302284
78MP0005164_abnormal_response_to0.91164350
79MP0003186_abnormal_redox_activity0.88943716
80MP0005167_abnormal_blood-brain_barrier0.88454704
81MP0005075_abnormal_melanosome_morpholog0.88208456
82MP0005083_abnormal_biliary_tract0.86562348
83MP0008438_abnormal_cutaneous_collagen0.83199436
84MP0003705_abnormal_hypodermis_morpholog0.79849253
85MP0008260_abnormal_autophagy0.77945790
86MP0004883_abnormal_blood_vessel0.76961997
87MP0009765_abnormal_xenobiotic_induced0.73784728
88MP0002136_abnormal_kidney_physiology0.72857913
89MP0002254_reproductive_system_inflammat0.72012485
90MP0004808_abnormal_hematopoietic_stem0.70266341
91MP0003045_fibrosis0.69700934
92MP0000490_abnormal_crypts_of0.69047225
93MP0000609_abnormal_liver_physiology0.68945081
94MP0008004_abnormal_stomach_pH0.68615854
95MP0002009_preneoplasia0.68035786
96MP0000015_abnormal_ear_pigmentation0.67374742
97MP0003795_abnormal_bone_structure0.65465792
98MP0005076_abnormal_cell_differentiation0.65215034
99MP0000371_diluted_coat_color0.63012115
100MP0008874_decreased_physiological_sensi0.61411156
101MP0005319_abnormal_enzyme/_coenzyme0.60599176
102MP0002277_abnormal_respiratory_mucosa0.59883876
103MP0005023_abnormal_wound_healing0.59821697
104MP0003195_calcinosis0.59655862
105MP0010329_abnormal_lipoprotein_level0.59638534
106MP0002332_abnormal_exercise_endurance0.59461881
107MP0004130_abnormal_muscle_cell0.58355688
108MP0000767_abnormal_smooth_muscle0.57360400
109MP0002928_abnormal_bile_duct0.57189217
110MP0008873_increased_physiological_sensi0.56799328
111MP0000920_abnormal_myelination0.56629955
112MP0002396_abnormal_hematopoietic_system0.56609053
113MP0003221_abnormal_cardiomyocyte_apopto0.56186482
114MP0001915_intracranial_hemorrhage0.55952741
115MP0005257_abnormal_intraocular_pressure0.54967534
116MP0005584_abnormal_enzyme/coenzyme_acti0.54027822
117MP0001873_stomach_inflammation0.53655653
118MP0001663_abnormal_digestive_system0.53430851
119MP0000598_abnormal_liver_morphology0.51987737
120MP0005084_abnormal_gallbladder_morpholo0.51896599
121MP0005388_respiratory_system_phenotype0.48338323
122MP0002133_abnormal_respiratory_system0.48338323
123MP0005535_abnormal_body_temperature0.46219906
124MP0005381_digestive/alimentary_phenotyp0.45824948
125MP0005376_homeostasis/metabolism_phenot0.45734440

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)8.35254714
2Recurrent abscess formation (HP:0002722)7.71064997
3Recurrent bacterial skin infections (HP:0005406)6.81589498
4Eczematoid dermatitis (HP:0000976)6.74057366
5Recurrent gram-negative bacterial infections (HP:0005420)6.69050311
6Glomerulonephritis (HP:0000099)5.66601035
7Vacuolated lymphocytes (HP:0001922)5.39773302
8Abnormality of macrophages (HP:0004311)4.65215334
9Mediastinal lymphadenopathy (HP:0100721)4.38173984
10Dysostosis multiplex (HP:0000943)4.31120646
11Complement deficiency (HP:0004431)4.22162566
12Gingivitis (HP:0000230)4.22077255
13Increased cerebral lipofuscin (HP:0011813)4.18269271
14Recurrent skin infections (HP:0001581)4.13219584
15Abnormal delayed hypersensitivity skin test (HP:0002963)4.12147153
16Hypochromic microcytic anemia (HP:0004840)3.95345422
17Increased neuronal autofluorescent lipopigment (HP:0002074)3.89363084
18Obstructive lung disease (HP:0006536)3.79222129
19Chronic obstructive pulmonary disease (HP:0006510)3.79222129
20Encephalitis (HP:0002383)3.78028188
21Pustule (HP:0200039)3.60757463
22Increased IgE level (HP:0003212)3.54450817
23Urinary glycosaminoglycan excretion (HP:0003541)3.50784922
24Mucopolysacchariduria (HP:0008155)3.50784922
25Nephritis (HP:0000123)3.50505348
26Keratoconjunctivitis (HP:0001096)3.48731625
27Recurrent fungal infections (HP:0002841)3.45824260
28Myositis (HP:0100614)3.44314723
29Elevated erythrocyte sedimentation rate (HP:0003565)3.44235476
30Hypochromic anemia (HP:0001931)3.39235086
31* Abnormality of complement system (HP:0005339)3.38335643
32Disinhibition (HP:0000734)3.36156754
33Episodic fever (HP:0001954)3.35828391
34Abnormality of liposaccharide metabolism (HP:0010968)3.34921891
35Abnormality of glycosphingolipid metabolism (HP:0004343)3.34921891
36Abnormality of glycolipid metabolism (HP:0010969)3.34921891
37Chest pain (HP:0100749)3.32110183
38Periodontitis (HP:0000704)3.27267526
39Abnormality of polysaccharide metabolism (HP:0011012)3.26859403
40Abnormality of glycosaminoglycan metabolism (HP:0004371)3.26859403
41Abnormality of mucopolysaccharide metabolism (HP:0011020)3.26859403
42Orchitis (HP:0100796)3.24852128
43Amyloidosis (HP:0011034)3.19355272
44Cellulitis (HP:0100658)3.12886402
45Axonal loss (HP:0003447)3.12336632
46Stomatitis (HP:0010280)3.12106295
47Recurrent viral infections (HP:0004429)2.96786185
48Joint hemorrhage (HP:0005261)2.96464882
49Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.95286490
50Panhypogammaglobulinemia (HP:0003139)2.89706026
51Optic neuritis (HP:0100653)2.87280503
52Retrobulbar optic neuritis (HP:0100654)2.87280503
53Prostate neoplasm (HP:0100787)2.85770727
54Loss of speech (HP:0002371)2.83283507
55Thick nail (HP:0001805)2.80350345
56Interstitial pulmonary disease (HP:0006530)2.77351026
57Urticaria (HP:0001025)2.76503671
58Anorexia (HP:0002039)2.76418294
59T lymphocytopenia (HP:0005403)2.76237094
60Vasculitis (HP:0002633)2.70371007
61Abnormality of T cell number (HP:0011839)2.69244441
62Pulmonary embolism (HP:0002204)2.68955508
63Meningitis (HP:0001287)2.68108850
64Agnosia (HP:0010524)2.65246120
65Autoimmune thrombocytopenia (HP:0001973)2.63109257
66Petechiae (HP:0000967)2.63055907
67J-shaped sella turcica (HP:0002680)2.61227689
68Spontaneous hematomas (HP:0007420)2.57876373
69Abnormality of T cells (HP:0002843)2.53951572
70Recurrent cutaneous fungal infections (HP:0011370)2.53461212
71Chronic mucocutaneous candidiasis (HP:0002728)2.53461212
72Increased IgM level (HP:0003496)2.51510566
73Granulocytopenia (HP:0001913)2.50928894
74Microcytic anemia (HP:0001935)2.46375878
75Basal ganglia calcification (HP:0002135)2.44710135
76Myocardial infarction (HP:0001658)2.41738739
77Gangrene (HP:0100758)2.39946444
78Recurrent pneumonia (HP:0006532)2.39174434
79Pulmonary infiltrates (HP:0002113)2.38709859
80Abnormality of the pleura (HP:0002103)2.38473326
81Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.38307415
82Gastrointestinal infarctions (HP:0005244)2.36019080
83Sepsis (HP:0100806)2.34645260
84Osteomyelitis (HP:0002754)2.33310255
85Abnormality of the lumbar spine (HP:0100712)2.32728104
86Gingival bleeding (HP:0000225)2.32207466
87Lymphopenia (HP:0001888)2.29993211
88Abnormality of T cell physiology (HP:0011840)2.29723875
89Hepatosplenomegaly (HP:0001433)2.29560824
90Arterial thrombosis (HP:0004420)2.25887700
91Chronic otitis media (HP:0000389)2.24847902
92Abnormality of the prostate (HP:0008775)2.24839068
93Pathologic fracture (HP:0002756)2.24706172
94Poor head control (HP:0002421)2.24277558
95Increased serum ferritin (HP:0003281)2.23084112
96Upper motor neuron abnormality (HP:0002127)2.21407787
97Abnormal platelet volume (HP:0011876)2.20991449
98Osteolytic defects of the phalanges of the hand (HP:0009771)2.19535471
99Osteolytic defects of the hand bones (HP:0009699)2.19535471
100Peritonitis (HP:0002586)2.17297139
101Leukocytosis (HP:0001974)2.16159903
102Colitis (HP:0002583)2.15828584
103Abnormality of iron homeostasis (HP:0011031)2.14355290
104Abnormality of cells of the lymphoid lineage (HP:0012140)2.13455783
105Thoracic kyphosis (HP:0002942)2.11440974
106Purpura (HP:0000979)2.10780654
107Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.09415290
108Vertigo (HP:0002321)2.09203039
109Glomerulopathy (HP:0100820)2.09077622
110Epistaxis (HP:0000421)2.07392181
111Agammaglobulinemia (HP:0004432)2.06933609
112Abnormality of the peritoneum (HP:0002585)2.06731513
113Recurrent lower respiratory tract infections (HP:0002783)2.06198200
114Asymmetric septal hypertrophy (HP:0001670)2.05458441
115Abnormality of the heme biosynthetic pathway (HP:0010472)2.03881535
116Eosinophilia (HP:0001880)2.03159292
117Nasal polyposis (HP:0100582)2.02784332
118Abnormality of the endocardium (HP:0004306)2.02617484
119Spondylolisthesis (HP:0003302)2.01951595
120Keratitis (HP:0000491)2.01817531
121Inflammation of the large intestine (HP:0002037)1.99978066
122Prolonged bleeding time (HP:0003010)1.99018215
123Abnormality of the pericardium (HP:0001697)1.98043720
124Acne (HP:0001061)1.97208377
125Acute hepatic failure (HP:0006554)1.94648104
126Diminished motivation (HP:0000745)1.94119297
127Polyneuropathy (HP:0001271)1.93313370
128IgM deficiency (HP:0002850)1.92483527
129Abnormality of the vasculature of the conjunctiva (HP:0008054)1.91790615
130Deformed sella turcica (HP:0002681)1.91742061
131Hematochezia (HP:0002573)1.91714866
132Apathy (HP:0000741)1.90875514
133Menorrhagia (HP:0000132)1.89670100
134Viral hepatitis (HP:0006562)1.88560796
135Skin rash (HP:0000988)1.87885566
136Amaurosis fugax (HP:0100576)1.87374238
137Premature loss of primary teeth (HP:0006323)1.83995248
138Gastrointestinal inflammation (HP:0004386)1.83445096
139Keratoconjunctivitis sicca (HP:0001097)1.83431277
140Abnormality of the nasal mucosa (HP:0000433)1.82704648
141Slow saccadic eye movements (HP:0000514)1.81477901
142Bone pain (HP:0002653)1.81400743
143Polycythemia (HP:0001901)1.80658843
144Hypergammaglobulinemia (HP:0010702)1.80566645
145Hemoptysis (HP:0002105)1.80508062
146Skin ulcer (HP:0200042)1.80481733

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BLK5.84291748
2RIPK43.94925832
3IRAK43.68039782
4MAP4K13.28542977
5MAP3K143.24723756
6TYK22.83099053
7ERN12.75202738
8TBK12.71669111
9TNK22.59677240
10PRPF4B2.36742779
11MST1R2.25748160
12KIT2.15750368
13IRAK32.02963521
14TAOK11.90663030
15IKBKB1.87345245
16TAOK31.81382597
17TXK1.77119451
18BTK1.76948151
19CSK1.70045345
20FES1.69496842
21PBK1.68115577
22ZAP701.65107781
23IKBKE1.64906370
24JAK11.64036236
25HCK1.63252332
26SYK1.61252150
27CSF1R1.60535400
28EPHB11.59294516
29JAK31.58844375
30TEC1.54386495
31SIK31.50345860
32NEK91.50187144
33MAP3K131.39126620
34CAMK1D1.38712123
35FGR1.37845224
36LYN1.36741193
37TGFBR21.32273103
38PIM21.28416173
39MAP2K31.28271944
40BMX1.28080340
41CDK191.21697683
42STK101.21341924
43TRIB31.20007688
44CLK11.12754144
45LCK1.11701533
46JAK21.10056955
47KSR21.09503516
48MARK21.05294801
49GRK61.03331614
50RIPK11.02370262
51MAP3K110.98895169
52CHUK0.98312356
53TAOK20.97284455
54NME20.96788015
55BMPR20.95430544
56PRKD20.93786259
57PDK10.93279820
58MATK0.92213530
59ABL20.87130505
60PIM10.86904065
61GRK70.86749132
62PKN20.82176426
63RPS6KA40.81590363
64IRAK20.81249799
65CAMKK20.81119529
66MARK30.80392758
67ITK0.77450544
68PRKCD0.76437809
69DAPK20.74421989
70MAP3K70.74056689
71LRRK20.73839150
72CAMK1G0.73628403
73MAP3K60.73404508
74STK40.70774400
75TESK20.69170496
76YES10.66975023
77MAPK120.64861825
78MAPK70.64830216
79TTN0.64551919
80CAMKK10.64173664
81PTK2B0.63433333
82SIK20.62133063
83TRPM70.62102214
84EGFR0.60355973
85STK110.59872461
86HIPK20.58265295
87DYRK1B0.57308233
88ABL10.56903207
89MAP2K40.56667704
90SMG10.56432401
91EPHA30.52407039
92MAP3K20.52066954
93SGK30.49830595
94MAP3K50.47748126
95CDC42BPA0.46666136
96MAP3K30.45613347
97PTK60.45291520
98MST40.43906347
99FYN0.43324838
100CDK60.42389637
101FGFR40.42186448
102ADRBK20.42172003
103FGFR30.42143222
104MAPKAPK20.40732408
105RPS6KA60.40626627
106DAPK10.40193626
107SIK10.39868250
108PRKCQ0.39494190
109PRKCH0.39433759
110IGF1R0.39242648
111EIF2AK20.39122973
112DAPK30.38632843
113STK380.37933609
114MET0.37423825
115MAP3K10.36042038
116IRAK10.35872183
117PIK3CG0.34911299
118SCYL20.34491610
119RAF10.34008097
120MOS0.33764551
121RET0.33649952
122ERBB30.33173951
123PAK40.32280527
124NLK0.31872321
125KSR10.31632638
126MAP3K100.30724931
127MAP3K120.30587310
128RPS6KC10.30110986
129RPS6KL10.30110986
130PRKG20.29940943
131SGK20.28785488
132MAP2K60.28582697
133FLT30.28090300
134RPS6KA20.27314442
135PRKCZ0.27052799
136PDPK10.26560364

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051505.85501184
2Leishmaniasis_Homo sapiens_hsa051403.53351066
3Other glycan degradation_Homo sapiens_hsa005113.17607420
4Pertussis_Homo sapiens_hsa051333.01849743
5Glycosaminoglycan degradation_Homo sapiens_hsa005312.86194536
6Lysosome_Homo sapiens_hsa041422.58631147
7Complement and coagulation cascades_Homo sapiens_hsa046102.53322802
8Legionellosis_Homo sapiens_hsa051342.49147698
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.44665789
10Osteoclast differentiation_Homo sapiens_hsa043802.36275481
11Graft-versus-host disease_Homo sapiens_hsa053322.31318629
12Tuberculosis_Homo sapiens_hsa051522.30315789
13Malaria_Homo sapiens_hsa051442.24677426
14NF-kappa B signaling pathway_Homo sapiens_hsa040642.07438377
15Phagosome_Homo sapiens_hsa041451.92035085
16Rheumatoid arthritis_Homo sapiens_hsa053231.84570552
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.80396106
18NOD-like receptor signaling pathway_Homo sapiens_hsa046211.75647369
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.74001497
20Salmonella infection_Homo sapiens_hsa051321.70623843
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.66254825
22Measles_Homo sapiens_hsa051621.64647490
23B cell receptor signaling pathway_Homo sapiens_hsa046621.64197906
24Allograft rejection_Homo sapiens_hsa053301.60967446
25Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.55627164
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.54662775
27Hematopoietic cell lineage_Homo sapiens_hsa046401.48820284
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.44559296
29Chemokine signaling pathway_Homo sapiens_hsa040621.42817703
30Influenza A_Homo sapiens_hsa051641.39872271
31Asthma_Homo sapiens_hsa053101.39755970
32Toxoplasmosis_Homo sapiens_hsa051451.38618910
33Caffeine metabolism_Homo sapiens_hsa002321.31084216
34Prion diseases_Homo sapiens_hsa050201.30441740
35Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.30337078
36Antigen processing and presentation_Homo sapiens_hsa046121.27338511
37TNF signaling pathway_Homo sapiens_hsa046681.26749040
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.22167743
39Shigellosis_Homo sapiens_hsa051311.20816499
40Apoptosis_Homo sapiens_hsa042101.11521656
41Type I diabetes mellitus_Homo sapiens_hsa049401.11433610
42Non-small cell lung cancer_Homo sapiens_hsa052231.10207806
43African trypanosomiasis_Homo sapiens_hsa051431.06691311
44Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05908477
45Jak-STAT signaling pathway_Homo sapiens_hsa046301.05885687
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.01103672
47* Herpes simplex infection_Homo sapiens_hsa051681.00003950
48Amoebiasis_Homo sapiens_hsa051460.96853057
49Leukocyte transendothelial migration_Homo sapiens_hsa046700.96845588
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95078109
51Viral myocarditis_Homo sapiens_hsa054160.93633662
52Primary immunodeficiency_Homo sapiens_hsa053400.82983090
53Pentose and glucuronate interconversions_Homo sapiens_hsa000400.80793307
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80609649
55Hepatitis B_Homo sapiens_hsa051610.75203376
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73392899
57AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.72683013
58Renal cell carcinoma_Homo sapiens_hsa052110.71194455
59Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70292511
60Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69266614
61Arachidonic acid metabolism_Homo sapiens_hsa005900.68814037
62Hepatitis C_Homo sapiens_hsa051600.67944365
63Platelet activation_Homo sapiens_hsa046110.66356759
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.64861731
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64511687
66FoxO signaling pathway_Homo sapiens_hsa040680.60102376
67Acute myeloid leukemia_Homo sapiens_hsa052210.58322442
68Notch signaling pathway_Homo sapiens_hsa043300.57353218
69Regulation of autophagy_Homo sapiens_hsa041400.56549520
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56395441
71Choline metabolism in cancer_Homo sapiens_hsa052310.56066873
72Autoimmune thyroid disease_Homo sapiens_hsa053200.55509311
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54052396
74GnRH signaling pathway_Homo sapiens_hsa049120.53800152
75Endometrial cancer_Homo sapiens_hsa052130.52186892
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50964578
77HTLV-I infection_Homo sapiens_hsa051660.50421300
78Dorso-ventral axis formation_Homo sapiens_hsa043200.50354343
79Pancreatic cancer_Homo sapiens_hsa052120.48908934
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48139694
81Colorectal cancer_Homo sapiens_hsa052100.47874583
82T cell receptor signaling pathway_Homo sapiens_hsa046600.47467485
83MAPK signaling pathway_Homo sapiens_hsa040100.45181387
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44575894
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.44356685
86Type II diabetes mellitus_Homo sapiens_hsa049300.43643685
87Inositol phosphate metabolism_Homo sapiens_hsa005620.42326916
88Chronic myeloid leukemia_Homo sapiens_hsa052200.42224424
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.41815301
90mTOR signaling pathway_Homo sapiens_hsa041500.41804923
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.41517855
92Renin-angiotensin system_Homo sapiens_hsa046140.38353012
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.38323599
94Sphingolipid metabolism_Homo sapiens_hsa006000.37943127
95Rap1 signaling pathway_Homo sapiens_hsa040150.37487290
96ABC transporters_Homo sapiens_hsa020100.36859487
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.34946988
98Histidine metabolism_Homo sapiens_hsa003400.33713603
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.33499686
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30907773
101ErbB signaling pathway_Homo sapiens_hsa040120.30629760
102Endocytosis_Homo sapiens_hsa041440.28914057
103Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27501558
104Epstein-Barr virus infection_Homo sapiens_hsa051690.26820095
105HIF-1 signaling pathway_Homo sapiens_hsa040660.26310383
106Prolactin signaling pathway_Homo sapiens_hsa049170.25233822
107Pentose phosphate pathway_Homo sapiens_hsa000300.25229343
108Mineral absorption_Homo sapiens_hsa049780.25099079
109Collecting duct acid secretion_Homo sapiens_hsa049660.21914763
110Insulin resistance_Homo sapiens_hsa049310.21180194
111Systemic lupus erythematosus_Homo sapiens_hsa053220.21146357
112Proteoglycans in cancer_Homo sapiens_hsa052050.19511146
113VEGF signaling pathway_Homo sapiens_hsa043700.19215172
114Starch and sucrose metabolism_Homo sapiens_hsa005000.18388475
115Steroid biosynthesis_Homo sapiens_hsa001000.18005475
116Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.16280379
117Primary bile acid biosynthesis_Homo sapiens_hsa001200.13875954
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.13391718
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.11613231
120Viral carcinogenesis_Homo sapiens_hsa052030.11283216
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.11170057
122Small cell lung cancer_Homo sapiens_hsa052220.10471332
123Arginine biosynthesis_Homo sapiens_hsa002200.10420243

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