CGGBP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of neurotransmitter secretion (GO:0046929)4.98559369
2nerve growth factor signaling pathway (GO:0038180)4.88962171
3regulation of Golgi to plasma membrane protein transport (GO:0042996)4.85155207
4positive regulation of granulocyte differentiation (GO:0030854)4.79185055
5megakaryocyte development (GO:0035855)4.44994025
6nuclear pore complex assembly (GO:0051292)4.21422468
7negative regulation of erythrocyte differentiation (GO:0045647)4.07389598
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.01545230
9Rap protein signal transduction (GO:0032486)3.96957123
10regulation of B cell receptor signaling pathway (GO:0050855)3.94543577
11negative regulation of neurotransmitter transport (GO:0051589)3.94066349
12histone H2A acetylation (GO:0043968)3.92224026
13mitotic sister chromatid cohesion (GO:0007064)3.85689805
14nuclear pore organization (GO:0006999)3.83510320
15DNA unwinding involved in DNA replication (GO:0006268)3.81545702
16regulation of platelet aggregation (GO:0090330)3.79624605
17positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.76033877
18negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.69065133
19negative regulation of cell killing (GO:0031342)3.69065133
20protein localization to kinetochore (GO:0034501)3.68724710
21positive regulation of vasculogenesis (GO:2001214)3.67890774
22antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.65316463
23positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.61585501
24antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.61261863
25antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.61261863
26mitotic chromosome condensation (GO:0007076)3.48450209
27negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.43091586
28B cell receptor signaling pathway (GO:0050853)3.42310777
29ribosomal small subunit assembly (GO:0000028)3.39120164
30phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.38469459
31mitotic G2 DNA damage checkpoint (GO:0007095)3.36681367
32antigen processing and presentation of endogenous antigen (GO:0019883)3.36606091
33protein localization to chromosome, centromeric region (GO:0071459)3.25394380
34regulation of nucleobase-containing compound transport (GO:0032239)3.22190001
35regulation of spindle organization (GO:0090224)3.20767895
36dosage compensation (GO:0007549)3.19763630
37thrombin receptor signaling pathway (GO:0070493)3.17805413
38pore complex assembly (GO:0046931)3.13473649
39neutrophil activation involved in immune response (GO:0002283)3.08244889
40viral transcription (GO:0019083)3.07337161
41regulation of erythrocyte differentiation (GO:0045646)3.05728719
42negative regulation of fibroblast apoptotic process (GO:2000270)3.04461917
43translational termination (GO:0006415)3.02282585
44definitive hemopoiesis (GO:0060216)3.02261426
45regulation of B cell differentiation (GO:0045577)3.00838398
46myeloid cell development (GO:0061515)2.95305943
47ether lipid metabolic process (GO:0046485)2.91178856
48positive regulation of alpha-beta T cell proliferation (GO:0046641)2.90277126
49regulation of T-helper 1 cell differentiation (GO:0045625)2.89946462
50regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.88188863
51detection of other organism (GO:0098543)2.88054701
52regulation of gamma-delta T cell differentiation (GO:0045586)2.87657446
53regulation of histone H3-K9 methylation (GO:0051570)2.87242438
54regulation of sister chromatid cohesion (GO:0007063)2.86223148
55regulation of granulocyte differentiation (GO:0030852)2.84241306
56mitotic G2/M transition checkpoint (GO:0044818)2.83381618
57mitotic nuclear envelope disassembly (GO:0007077)2.83361775
58sister chromatid segregation (GO:0000819)2.82723685
59positive regulation of Rap GTPase activity (GO:0032854)2.81600195
60negative regulation of DNA repair (GO:0045738)2.80844349
61regulation of gamma-delta T cell activation (GO:0046643)2.80329537
62response to interleukin-15 (GO:0070672)2.79745656
63Arp2/3 complex-mediated actin nucleation (GO:0034314)2.79561202
64detection of bacterium (GO:0016045)2.78822775
65positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.77085141
66positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.77085141
67positive regulation of mitotic sister chromatid separation (GO:1901970)2.77085141
68DNA topological change (GO:0006265)2.76783555
69negative thymic T cell selection (GO:0045060)2.74280392
70antigen processing and presentation via MHC class Ib (GO:0002475)2.73617752
71cellular response to nerve growth factor stimulus (GO:1990090)2.71759464
72response to nerve growth factor (GO:1990089)2.71759464
73mitotic metaphase plate congression (GO:0007080)2.71066789
74membrane disassembly (GO:0030397)2.70288417
75nuclear envelope disassembly (GO:0051081)2.70288417
76positive regulation of chromosome segregation (GO:0051984)2.70113049
77negative regulation of histone methylation (GO:0031061)2.69705288
78histone mRNA catabolic process (GO:0071044)2.69514248
79leukocyte tethering or rolling (GO:0050901)2.68222422
80negative regulation of T-helper cell differentiation (GO:0045623)2.67873103
81negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.67873103
82regulation of RNA export from nucleus (GO:0046831)2.67854706
83nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.67045516
84maturation of SSU-rRNA (GO:0030490)2.66230423
85regulation of mitotic spindle organization (GO:0060236)2.64854745
86negative regulation of protein localization to plasma membrane (GO:1903077)2.61847160
87germ cell migration (GO:0008354)2.61576068
88mRNA stabilization (GO:0048255)2.60915257
89RNA stabilization (GO:0043489)2.60915257
90T cell homeostasis (GO:0043029)2.58803740
91poly(A)+ mRNA export from nucleus (GO:0016973)2.58483449
923-UTR-mediated mRNA stabilization (GO:0070935)2.58299294
93translational elongation (GO:0006414)2.57249117
94histone H4-K16 acetylation (GO:0043984)2.56294286
95granulocyte differentiation (GO:0030851)2.55225573
96negative T cell selection (GO:0043383)2.54978983
97DNA replication initiation (GO:0006270)2.54826940
98regulation of alpha-beta T cell proliferation (GO:0046640)2.54716589
99negative regulation of phagocytosis (GO:0050765)2.54562814
100regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.54271080
101synapsis (GO:0007129)2.53993628
102regulation of establishment of cell polarity (GO:2000114)2.53898377
103positive regulation of interleukin-2 production (GO:0032743)2.53160614
104regulation of platelet activation (GO:0010543)2.53004593
105kinetochore organization (GO:0051383)2.52561941
106negative regulation of establishment of protein localization to plasma membrane (GO:0090005)2.52120555
107negative regulation of T cell mediated immunity (GO:0002710)2.51923713
108DNA strand elongation involved in DNA replication (GO:0006271)2.51575393
109regulation of Rap GTPase activity (GO:0032317)2.50896274
110SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.50168247
111regulation of interferon-beta biosynthetic process (GO:0045357)2.49598057
112histamine secretion (GO:0001821)2.48441485
113translational initiation (GO:0006413)2.47450195
114positive regulation of B cell differentiation (GO:0045579)2.47249760
115histone H4 acetylation (GO:0043967)2.46865510
116regulation of interleukin-12 biosynthetic process (GO:0045075)2.46206616
117chromatin assembly (GO:0031497)2.44600772
118protein localization to chromosome (GO:0034502)2.44459918
119histone H3-K9 demethylation (GO:0033169)2.44194170
120DNA synthesis involved in DNA repair (GO:0000731)2.44174311
121protein targeting to ER (GO:0045047)2.43971030
122positive regulation of gamma-delta T cell activation (GO:0046645)2.43858283
123translesion synthesis (GO:0019985)2.43857264
124germinal center formation (GO:0002467)2.43132457
125regulation of fibroblast apoptotic process (GO:2000269)2.42362180
126cotranslational protein targeting to membrane (GO:0006613)2.42167458
127monoubiquitinated protein deubiquitination (GO:0035520)2.41225761
128positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.41162954
129mitotic recombination (GO:0006312)2.40874040
130attachment of spindle microtubules to kinetochore (GO:0008608)2.40846172
131nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.40244523
132regulation of meiosis I (GO:0060631)2.39771084
133ribosomal small subunit biogenesis (GO:0042274)2.39649732
134histone-serine phosphorylation (GO:0035404)2.38867913
135gene silencing by RNA (GO:0031047)2.38250046
136folic acid-containing compound biosynthetic process (GO:0009396)2.37898467
137regulation of protein heterodimerization activity (GO:0043497)2.37217866
138chromosome condensation (GO:0030261)2.36972553
139interkinetic nuclear migration (GO:0022027)2.36454082
140positive regulation of interferon-alpha production (GO:0032727)2.36410392
141DNA strand elongation (GO:0022616)2.35977666
142viral life cycle (GO:0019058)2.34976824
143hepatocyte apoptotic process (GO:0097284)2.34438654
144DNA duplex unwinding (GO:0032508)2.34292798
145mRNA modification (GO:0016556)2.33223539
146DNA geometric change (GO:0032392)2.33180683
147positive T cell selection (GO:0043368)2.32552214
148metaphase plate congression (GO:0051310)2.32327489
149establishment of protein localization to endoplasmic reticulum (GO:0072599)2.32208540
150negative regulation of RNA splicing (GO:0033119)2.32169624
151cellular response to fluid shear stress (GO:0071498)2.31876435
152positive regulation of T cell cytokine production (GO:0002726)2.30918496
153embryonic process involved in female pregnancy (GO:0060136)2.30465719
154natural killer cell differentiation (GO:0001779)2.30273003
155DNA replication-dependent nucleosome organization (GO:0034723)2.29615086
156DNA replication-dependent nucleosome assembly (GO:0006335)2.29615086
157sister chromatid cohesion (GO:0007062)2.29516532
158IMP biosynthetic process (GO:0006188)2.29252343
159regulation of pigment cell differentiation (GO:0050932)2.29152716
160negative regulation of thymocyte apoptotic process (GO:0070244)2.28689727
161negative regulation of T cell apoptotic process (GO:0070233)2.28534970
162negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.27821526
163histone H4-K5 acetylation (GO:0043981)2.27811964
164histone H4-K8 acetylation (GO:0043982)2.27811964
165mitotic sister chromatid segregation (GO:0000070)2.25969328
166cellular protein complex disassembly (GO:0043624)2.22675801
167regulation of interferon-alpha production (GO:0032647)2.22523131
168nuclear envelope organization (GO:0006998)2.22436181
169glucocorticoid receptor signaling pathway (GO:0042921)2.22070824
170regulation of mRNA stability (GO:0043488)2.21904380
171protein localization to endoplasmic reticulum (GO:0070972)2.20869933
172telomere maintenance via semi-conservative replication (GO:0032201)2.19690844
173meiotic chromosome segregation (GO:0045132)2.19348803
174chromatin assembly or disassembly (GO:0006333)2.18103056
175alternative mRNA splicing, via spliceosome (GO:0000380)2.17932441
176telomere maintenance via recombination (GO:0000722)2.16928367
177nuclear-transcribed mRNA catabolic process (GO:0000956)2.16858235
178establishment of chromosome localization (GO:0051303)2.16571576
179endothelial tube morphogenesis (GO:0061154)2.16269409
180morphogenesis of an endothelium (GO:0003159)2.16269409
181cellular response to interferon-alpha (GO:0035457)2.16045493

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.26284009
2GATA1_22025678_ChIP-Seq_K562_Human5.49781034
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.74506906
4EGR1_19374776_ChIP-ChIP_THP-1_Human4.33024366
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.16248861
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.92424122
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.73933229
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.65457338
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.63944517
10* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.60905065
11* CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.60199183
12WT1_19549856_ChIP-ChIP_CCG9911_Human2.49282015
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.46349366
14SMAD_19615063_ChIP-ChIP_OVARY_Human2.20998067
15MYC_22102868_ChIP-Seq_BL_Human2.14876609
16FUS_26573619_Chip-Seq_HEK293_Human2.12617860
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.11715822
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.06339724
19ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.06334541
20RUNX_20019798_ChIP-Seq_JUKART_Human2.03982265
21AR_21909140_ChIP-Seq_LNCAP_Human2.03674695
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.03277348
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.02714687
24E2F1_21310950_ChIP-Seq_MCF-7_Human1.93594516
25IGF1R_20145208_ChIP-Seq_DFB_Human1.92475974
26IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.90256422
27MYC_19079543_ChIP-ChIP_MESCs_Mouse1.88360625
28MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.88108704
29IRF8_21731497_ChIP-ChIP_J774_Mouse1.87588800
30RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.86769958
31Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.80226013
32STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.79376915
33KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.75108801
34PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.74701530
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73029966
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.72659720
37SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.72328388
38* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.70348286
39* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.69417329
40TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.69358530
41STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.60370946
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.59540259
43* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.57377208
44SPI1_23547873_ChIP-Seq_NB4_Human1.53764495
45TAF15_26573619_Chip-Seq_HEK293_Human1.53706442
46* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53034308
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.52440757
48VDR_21846776_ChIP-Seq_THP-1_Human1.51765950
49* EWS_26573619_Chip-Seq_HEK293_Human1.49658526
50MYB_26560356_Chip-Seq_TH2_Human1.49264828
51* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.48155732
52SALL1_21062744_ChIP-ChIP_HESCs_Human1.48081185
53ELK1_19687146_ChIP-ChIP_HELA_Human1.47896196
54IRF8_27001747_Chip-Seq_BMDM_Mouse1.46439176
55CLOCK_20551151_ChIP-Seq_293T_Human1.42006216
56CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41124109
57MYB_26560356_Chip-Seq_TH1_Human1.40189730
58SCL_19346495_ChIP-Seq_HPC-7_Human1.38447074
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.37845496
60HIF1A_21447827_ChIP-Seq_MCF-7_Human1.36900547
61* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.35895736
62MAF_26560356_Chip-Seq_TH1_Human1.33873872
63OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33201185
64XRN2_22483619_ChIP-Seq_HELA_Human1.32415486
65SALL4_18804426_ChIP-ChIP_XEN_Mouse1.32410355
66RBPJ_22232070_ChIP-Seq_NCS_Mouse1.32200528
67TCF7_22412390_ChIP-Seq_EML_Mouse1.29078617
68MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27727512
69* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27343959
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.26143144
71PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25603952
72VDR_24763502_ChIP-Seq_THP-1_Human1.24974567
73UTX_26944678_Chip-Seq_JUKART_Human1.23801992
74TP63_17297297_ChIP-ChIP_HaCaT_Human1.23798276
75VDR_23849224_ChIP-Seq_CD4+_Human1.22392854
76* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22334900
77GBX2_23144817_ChIP-Seq_PC3_Human1.19704274
78FLI1_27457419_Chip-Seq_LIVER_Mouse1.19656507
79* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.19620463
80STAT4_19710469_ChIP-ChIP_TH1__Mouse1.19372811
81CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18956300
82ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18647802
83IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.17284752
84GATA3_27048872_Chip-Seq_THYMUS_Human1.17223212
85EZH2_27294783_Chip-Seq_NPCs_Mouse1.16992890
86NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.16700595
87NRF2_20460467_ChIP-Seq_MEFs_Mouse1.16700595
88STAT3_1855785_ChIP-Seq_MESCs_Mouse1.16443688
89MYCN_18555785_ChIP-Seq_MESCs_Mouse1.16392117
90CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.15915756
91RUNX1_22412390_ChIP-Seq_EML_Mouse1.15569584
92TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.15499740
93CREB1_15753290_ChIP-ChIP_HEK293T_Human1.14365307
94* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14337593
95TFEB_21752829_ChIP-Seq_HELA_Human1.13961726
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13912791
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13564239
98FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.13269036
99NANOG_18555785_Chip-Seq_ESCs_Mouse1.12184148
100TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.11515823
101SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09905378
102SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.09476528
103POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09320517
104ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08127397
105NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.07972365
106SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07461199
107GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07422554
108CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06413420
109SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.06303237
110KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.06229508
111KDM5A_27292631_Chip-Seq_BREAST_Human1.05614392
112MYC_18358816_ChIP-ChIP_MESCs_Mouse1.05529691
113RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.04915689
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04738888
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03116364
116FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02548053
117SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01500108
118SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00964327
119SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.00695266
120SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.00695266
121CHD1_26751641_Chip-Seq_LNCaP_Human0.97050416
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97017081
123ELK3_25401928_ChIP-Seq_HUVEC_Human0.96626081
124NANOG_18555785_ChIP-Seq_MESCs_Mouse0.96347858
125ER_23166858_ChIP-Seq_MCF-7_Human0.96337398
126FOXP3_21729870_ChIP-Seq_TREG_Human0.96123809
127PCGF2_27294783_Chip-Seq_ESCs_Mouse0.95574056
128CMYC_18555785_Chip-Seq_ESCs_Mouse0.95250074
129OCT4_21477851_ChIP-Seq_ESCs_Mouse0.94569007
130KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94503401
131PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94440197
132ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94408502
133E2F1_18555785_ChIP-Seq_MESCs_Mouse0.94207800
134PU_27001747_Chip-Seq_BMDM_Mouse0.93310310
135E2F1_18555785_Chip-Seq_ESCs_Mouse0.93304652
136* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93196848
137DCP1A_22483619_ChIP-Seq_HELA_Human0.93155926
138GATA2_22383799_ChIP-Seq_G1ME_Mouse0.92553314
139TTF2_22483619_ChIP-Seq_HELA_Human0.92523069
140POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.92033273
141CIITA_25753668_ChIP-Seq_RAJI_Human0.91634997
142HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.91561337
143SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.91409049
144PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.89127229
145SUZ12_18555785_Chip-Seq_ESCs_Mouse0.88668912
146VDR_24787735_ChIP-Seq_THP-1_Human0.87906675
147* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87648026
148ETS1_22383799_ChIP-Seq_G1ME_Mouse0.87364833
149TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87046239
150P53_22387025_ChIP-Seq_ESCs_Mouse0.87024178
151STAT3_23295773_ChIP-Seq_U87_Human0.86975871
152* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.86742774
153FLI1_21867929_ChIP-Seq_TH2_Mouse0.86678166
154ZFP57_27257070_Chip-Seq_ESCs_Mouse0.85632489
155PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84674333
156TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83854502
157SUZ12_27294783_Chip-Seq_NPCs_Mouse0.83551894

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps2.98211366
2MP0003705_abnormal_hypodermis_morpholog2.84277576
3MP0004808_abnormal_hematopoietic_stem2.30802517
4MP0003300_gastrointestinal_ulcer2.24099391
5MP0008057_abnormal_DNA_replication2.17771460
6MP0010307_abnormal_tumor_latency2.12414347
7MP0005076_abnormal_cell_differentiation2.04490398
8MP0003693_abnormal_embryo_hatching2.00652910
9MP0002396_abnormal_hematopoietic_system1.99729461
10MP0003656_abnormal_erythrocyte_physiolo1.98474436
11MP0006054_spinal_hemorrhage1.95868684
12MP0001851_eye_inflammation1.95519211
13MP0009278_abnormal_bone_marrow1.94826361
14MP0004957_abnormal_blastocyst_morpholog1.91686867
15MP0001835_abnormal_antigen_presentation1.91055163
16MP0010094_abnormal_chromosome_stability1.88023290
17MP0003077_abnormal_cell_cycle1.87098283
18MP0003303_peritoneal_inflammation1.86858617
19MP0002877_abnormal_melanocyte_morpholog1.86540496
20MP0002166_altered_tumor_susceptibility1.84248718
21MP0008007_abnormal_cellular_replicative1.74397749
22MP0010234_abnormal_vibrissa_follicle1.72146335
23MP0000465_gastrointestinal_hemorrhage1.71588609
24MP0003111_abnormal_nucleus_morphology1.67106826
25MP0000685_abnormal_immune_system1.60584474
26MP0008438_abnormal_cutaneous_collagen1.60184904
27MP0003183_abnormal_peptide_metabolism1.59968693
28MP0000490_abnormal_crypts_of1.59519708
29MP0000015_abnormal_ear_pigmentation1.59151368
30MP0003436_decreased_susceptibility_to1.58104085
31MP0005397_hematopoietic_system_phenotyp1.55077703
32MP0001545_abnormal_hematopoietic_system1.55077703
33MP0005409_darkened_coat_color1.54467771
34MP0002006_tumorigenesis1.49061024
35MP0000350_abnormal_cell_proliferation1.47220035
36MP0001188_hyperpigmentation1.42474821
37MP0005075_abnormal_melanosome_morpholog1.40222826
38MP0003448_altered_tumor_morphology1.38752013
39MP0003221_abnormal_cardiomyocyte_apopto1.35562008
40MP0003566_abnormal_cell_adhesion1.35421212
41MP0002398_abnormal_bone_marrow1.33706785
42MP0002452_abnormal_antigen_presenting1.30058805
43MP0008877_abnormal_DNA_methylation1.29868173
44MP0001879_abnormal_lymphatic_vessel1.29569585
45MP0001800_abnormal_humoral_immune1.28673611
46MP0009785_altered_susceptibility_to1.28557425
47MP0002086_abnormal_extraembryonic_tissu1.26511414
48MP0003567_abnormal_fetal_cardiomyocyte1.23735529
49MP0005023_abnormal_wound_healing1.23646075
50MP0002009_preneoplasia1.23576598
51MP0000733_abnormal_muscle_development1.23514061
52MP0009697_abnormal_copulation1.22398681
53MP0001730_embryonic_growth_arrest1.21200974
54MP0010155_abnormal_intestine_physiology1.21068280
55MP0009053_abnormal_anal_canal1.18790966
56MP0000537_abnormal_urethra_morphology1.17216884
57MP0004197_abnormal_fetal_growth/weight/1.15970758
58MP0002420_abnormal_adaptive_immunity1.15389874
59MP0001819_abnormal_immune_cell1.15279081
60MP0005464_abnormal_platelet_physiology1.15232892
61MP0005000_abnormal_immune_tolerance1.15056013
62MP0005025_abnormal_response_to1.14420760
63MP0000858_altered_metastatic_potential1.13718108
64MP0000569_abnormal_digit_pigmentation1.13619456
65MP0002405_respiratory_system_inflammati1.13155868
66MP0002722_abnormal_immune_system1.13136053
67MP0004147_increased_porphyrin_level1.13091784
68MP0003724_increased_susceptibility_to1.12146878
69MP0009333_abnormal_splenocyte_physiolog1.11522759
70MP0001672_abnormal_embryogenesis/_devel1.11048922
71MP0005380_embryogenesis_phenotype1.11048922
72MP0000689_abnormal_spleen_morphology1.10849554
73MP0002088_abnormal_embryonic_growth/wei1.10230122
74MP0003984_embryonic_growth_retardation1.08996023
75MP0002019_abnormal_tumor_incidence1.07911736
76MP0000716_abnormal_immune_system1.07423317
77MP0002723_abnormal_immune_serum1.07280920
78MP0001697_abnormal_embryo_size1.06082374
79MP0002419_abnormal_innate_immunity1.04981903
80MP0005671_abnormal_response_to1.04717855
81MP0004947_skin_inflammation1.01234187
82MP0003763_abnormal_thymus_physiology1.01173984
83MP0000703_abnormal_thymus_morphology1.00205500
84MP0002429_abnormal_blood_cell0.99555010
85MP0004484_altered_response_of0.99393875
86MP0001790_abnormal_immune_system0.98639976
87MP0005387_immune_system_phenotype0.98639976
88MP0010368_abnormal_lymphatic_system0.98186418
89MP0009703_decreased_birth_body0.96987926
90MP0001853_heart_inflammation0.96410007
91MP0010030_abnormal_orbit_morphology0.94608486
92MP0003091_abnormal_cell_migration0.94507681
93MP0001533_abnormal_skeleton_physiology0.93463103
94MP0003828_pulmonary_edema0.93204394
95MP0003279_aneurysm0.92964409
96MP0001915_intracranial_hemorrhage0.92914107
97MP0002084_abnormal_developmental_patter0.90782421
98MP0005174_abnormal_tail_pigmentation0.89769295
99MP0002080_prenatal_lethality0.89434155
100MP0008004_abnormal_stomach_pH0.88600800
101MP0000372_irregular_coat_pigmentation0.88379924
102MP0002148_abnormal_hypersensitivity_rea0.88164331
103MP0003890_abnormal_embryonic-extraembry0.86612205
104MP0003123_paternal_imprinting0.86378435
105MP0003943_abnormal_hepatobiliary_system0.86139759
106MP0001191_abnormal_skin_condition0.85218320
107MP0002085_abnormal_embryonic_tissue0.84886815
108MP0005220_abnormal_exocrine_pancreas0.83401132
109MP0010678_abnormal_skin_adnexa0.80079781
110MP0006082_CNS_inflammation0.79882762
111MP0000313_abnormal_cell_death0.79415122
112MP0000627_abnormal_mammary_gland0.79286593
113MP0008260_abnormal_autophagy0.79236237
114MP0005621_abnormal_cell_physiology0.79202936
115MP0001845_abnormal_inflammatory_respons0.78913107
116MP0005367_renal/urinary_system_phenotyp0.77784253
117MP0000516_abnormal_urinary_system0.77784253
118MP0002925_abnormal_cardiovascular_devel0.77714191
119MP0000371_diluted_coat_color0.77046951
120MP0002092_abnormal_eye_morphology0.76979489
121MP0003453_abnormal_keratinocyte_physiol0.76529246
122MP0009672_abnormal_birth_weight0.75716929
123MP0001177_atelectasis0.73178335
124MP0003172_abnormal_lysosome_physiology0.72559521
125MP0004185_abnormal_adipocyte_glucose0.67956802
126MP0000681_abnormal_thyroid_gland0.65649031
127MP0005388_respiratory_system_phenotype0.64708938
128MP0002133_abnormal_respiratory_system0.64708938
129MP0001784_abnormal_fluid_regulation0.61929421

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)4.24549058
2Papillary thyroid carcinoma (HP:0002895)3.99702480
3Thrombocytosis (HP:0001894)3.47977539
4T lymphocytopenia (HP:0005403)3.46867949
5Long clavicles (HP:0000890)3.46831082
6Acute lymphatic leukemia (HP:0006721)3.40320409
7Insidious onset (HP:0003587)3.17523981
8Termporal pattern (HP:0011008)3.17523981
9Hematochezia (HP:0002573)3.16060752
10Cystic hygroma (HP:0000476)3.10033676
11Subaortic stenosis (HP:0001682)3.05654410
12Abnormality of the left ventricular outflow tract (HP:0011103)3.05654410
13Abnormality of T cell number (HP:0011839)3.03123240
14Thyroid carcinoma (HP:0002890)3.02999557
15Panhypogammaglobulinemia (HP:0003139)3.01029250
16Dyschromatopsia (HP:0007641)2.88263799
17Epistaxis (HP:0000421)2.83573751
18Syringomyelia (HP:0003396)2.61697733
19Spinal cord lesions (HP:0100561)2.61697733
20Short 4th metacarpal (HP:0010044)2.57457297
21Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.57457297
22Osteolytic defects of the hand bones (HP:0009699)2.52861203
23Osteolytic defects of the phalanges of the hand (HP:0009771)2.52861203
24Subacute progressive viral hepatitis (HP:0006572)2.48887523
25Abnormal auditory evoked potentials (HP:0006958)2.48476352
26Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.44298270
27Degeneration of the lateral corticospinal tracts (HP:0002314)2.44298270
28B lymphocytopenia (HP:0010976)2.43696294
29Cutaneous melanoma (HP:0012056)2.41799521
30Lower limb asymmetry (HP:0100559)2.36947716
31Cellulitis (HP:0100658)2.36425035
32Recurrent viral infections (HP:0004429)2.35466815
33Eczematoid dermatitis (HP:0000976)2.31717572
34Abnormality of B cell number (HP:0010975)2.31564442
35Abnormal delayed hypersensitivity skin test (HP:0002963)2.30094721
36Arterial thrombosis (HP:0004420)2.27889946
37Chronic otitis media (HP:0000389)2.27543371
38Fatigue (HP:0012378)2.26260966
39Thickened calvaria (HP:0002684)2.25885058
40Bladder carcinoma (HP:0002862)2.24837351
41Bladder neoplasm (HP:0009725)2.24837351
42Autoimmune hemolytic anemia (HP:0001890)2.24316047
43Abnormality of the lumbar spine (HP:0100712)2.21255579
44Increased density of long bones (HP:0006392)2.20230461
45Bicuspid aortic valve (HP:0001647)2.19274421
46Acute myeloid leukemia (HP:0004808)2.18940383
47Aortic aneurysm (HP:0004942)2.18783504
48Protrusio acetabuli (HP:0003179)2.18685793
49Truncal obesity (HP:0001956)2.18664462
50Gingival bleeding (HP:0000225)2.18315715
51Interstitial pulmonary disease (HP:0006530)2.17598579
52Deviation of the thumb (HP:0009603)2.15993625
53Abnormality of the prostate (HP:0008775)2.15724408
54Abnormality of cells of the erythroid lineage (HP:0012130)2.15467076
55Encephalitis (HP:0002383)2.15448022
56Facial hemangioma (HP:0000329)2.15391093
57Agammaglobulinemia (HP:0004432)2.14122900
58Birth length less than 3rd percentile (HP:0003561)2.12942270
59Amaurosis fugax (HP:0100576)2.12158851
60Myositis (HP:0100614)2.11323499
61Acanthocytosis (HP:0001927)2.09440122
62Uterine leiomyosarcoma (HP:0002891)2.07586881
63Leiomyosarcoma (HP:0100243)2.07586881
64Capillary hemangiomas (HP:0005306)2.07113843
65Volvulus (HP:0002580)2.06984725
66Aortic dissection (HP:0002647)2.06262102
67Nephroblastoma (Wilms tumor) (HP:0002667)2.06176149
68Ankle contracture (HP:0006466)2.05849352
69Abnormality of the corticospinal tract (HP:0002492)2.05155155
70Cervical subluxation (HP:0003308)2.04972787
71Proximal placement of thumb (HP:0009623)2.02821682
72Abnormality of T cells (HP:0002843)2.02013167
73Colon cancer (HP:0003003)2.01714508
74Embryonal renal neoplasm (HP:0011794)2.01267166
75Abnormality of the calcaneus (HP:0008364)2.00332866
76Cutis marmorata (HP:0000965)1.98337929
77Abnormality of the 4th metacarpal (HP:0010012)1.96951763
78Amyotrophic lateral sclerosis (HP:0007354)1.96834311
79Cortical dysplasia (HP:0002539)1.95479734
80Asymmetry of the thorax (HP:0001555)1.94854014
81Absent frontal sinuses (HP:0002688)1.94305024
82Inflammation of the large intestine (HP:0002037)1.93839847
83Decreased skull ossification (HP:0004331)1.92507621
84Periodontitis (HP:0000704)1.92290456
85Viral hepatitis (HP:0006562)1.90808421
86Recurrent abscess formation (HP:0002722)1.90803553
87Broad palm (HP:0001169)1.90766789
88Reticulocytopenia (HP:0001896)1.90598211
89Meningitis (HP:0001287)1.90538719
90Spontaneous hematomas (HP:0007420)1.90097746
91Genu recurvatum (HP:0002816)1.89519788
92Granulocytopenia (HP:0001913)1.89412364
93Curly hair (HP:0002212)1.89347263
94Lymphedema (HP:0001004)1.89240820
95Disinhibition (HP:0000734)1.87859968
96Urinary urgency (HP:0000012)1.87377342
97Gastrointestinal inflammation (HP:0004386)1.87261371
98Abnormality of oral frenula (HP:0000190)1.86999164
99Papilledema (HP:0001085)1.86815198
100Dilatation of the ascending aorta (HP:0005111)1.86763038
101Freckling (HP:0001480)1.86309055
102Autoimmune thrombocytopenia (HP:0001973)1.85654219
103Mitral valve prolapse (HP:0001634)1.85513304
104Scanning speech (HP:0002168)1.85007734
105Ankyloglossia (HP:0010296)1.84329172
106Shallow orbits (HP:0000586)1.83668973
107Thoracolumbar scoliosis (HP:0002944)1.83289607
108Relative macrocephaly (HP:0004482)1.83013312
109Abnormality of the peritoneum (HP:0002585)1.81901830
110Abnormality of skull ossification (HP:0002703)1.81206294
111Abnormal platelet volume (HP:0011876)1.78644763
112Blepharitis (HP:0000498)1.77993749
113High pitched voice (HP:0001620)1.77779768
114Premature rupture of membranes (HP:0001788)1.77758123
115Selective tooth agenesis (HP:0001592)1.77710466
116Elevated erythrocyte sedimentation rate (HP:0003565)1.77106828
117Myelodysplasia (HP:0002863)1.77094493
118Rectal prolapse (HP:0002035)1.76987002
119Impaired vibration sensation in the lower limbs (HP:0002166)1.76967298
120Poikilocytosis (HP:0004447)1.76885826
121Severe combined immunodeficiency (HP:0004430)1.76778955
122Cerebral aneurysm (HP:0004944)1.76193468
123Basal cell carcinoma (HP:0002671)1.75859399
124Combined immunodeficiency (HP:0005387)1.75811834
125Malignant gastrointestinal tract tumors (HP:0006749)1.75485559
126Gastrointestinal carcinoma (HP:0002672)1.75485559
127Radial bowing (HP:0002986)1.74195839
12811 pairs of ribs (HP:0000878)1.73470846
129Chest pain (HP:0100749)1.72806980
130Myocardial infarction (HP:0001658)1.72354657
131Increased mean platelet volume (HP:0011877)1.71890172
132Abnormality of the vasculature of the conjunctiva (HP:0008054)1.71312009
133Lower limb muscle weakness (HP:0007340)1.71249261
134Vertebral arch anomaly (HP:0008438)1.70565722
135Colitis (HP:0002583)1.70127956
136Deep philtrum (HP:0002002)1.69894034
137Heterochromia iridis (HP:0001100)1.69892594
138Peritonitis (HP:0002586)1.69703256
139Persistence of primary teeth (HP:0006335)1.69157123
140Recurrent fungal infections (HP:0002841)1.69126896
141Abnormal platelet function (HP:0011869)1.69098079
142Impaired platelet aggregation (HP:0003540)1.69098079
143Recurrent bronchitis (HP:0002837)1.68805637
144Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.68556083
145Orchitis (HP:0100796)1.68514064
146Abnormality of the fingertips (HP:0001211)1.67797550
147Stomatitis (HP:0010280)1.67202647
148Eosinophilia (HP:0001880)1.66813510
149Menstrual irregularities (HP:0000858)1.66469636
150Central scotoma (HP:0000603)1.65735260
151Conjunctival telangiectasia (HP:0000524)1.65472895
152Thyroiditis (HP:0100646)1.65183941
153Abnormality of chromosome segregation (HP:0002916)1.63135749
154Choroideremia (HP:0001139)1.62873976
155Recurrent bacterial skin infections (HP:0005406)1.62737406
156Ulnar bowing (HP:0003031)1.62312454
157Menorrhagia (HP:0000132)1.62195079
158Osteomyelitis (HP:0002754)1.62100301
159IgM deficiency (HP:0002850)1.60898069
160Transitional cell carcinoma of the bladder (HP:0006740)1.60422223
161Abnormality of the anterior horn cell (HP:0006802)1.59425206
162Degeneration of anterior horn cells (HP:0002398)1.59425206
163Biliary tract neoplasm (HP:0100574)1.58825306
164Glossoptosis (HP:0000162)1.58722161
165Atresia of the external auditory canal (HP:0000413)1.58711918
166Micronodular cirrhosis (HP:0001413)1.58108242
167Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.58034744
168Metaphyseal cupping (HP:0003021)1.57842920
169Exostoses (HP:0100777)1.55917606
170Abnormal number of erythroid precursors (HP:0012131)1.54807902
171Mediastinal lymphadenopathy (HP:0100721)1.53523080

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PKN22.99709177
2CDC72.63412055
3EEF2K2.37778924
4WEE12.36708434
5MAP3K102.33218659
6BRD42.30895725
7TRIB32.26971298
8SIK32.25806121
9TXK2.18640171
10CDK192.08209798
11FRK2.07767723
12TGFBR12.02959120
13TRIM281.99037903
14RPS6KB21.97478293
15RPS6KA41.96660081
16NEK21.95051939
17STK101.93494804
18RIPK41.89009819
19FLT31.87974404
20PRPF4B1.81866618
21BCR1.80564142
22LRRK21.80361269
23NME21.78952086
24SCYL21.69310874
25CDK61.67468981
26JAK31.64590423
27STK31.62191060
28DYRK31.55252202
29LATS11.54683637
30MKNK11.51384584
31ZAP701.48966902
32BUB11.48018104
33MAP3K141.46145527
34BRSK21.44917848
35SYK1.44816359
36TYK21.44613773
37TAF11.43619714
38CDK41.36666745
39MAP3K61.36359968
40CDK121.32457126
41PLK41.29252302
42MAP2K31.28868506
43FGFR31.28510134
44TGFBR21.26731462
45PTK61.24738006
46BTK1.23087723
47SGK21.22661968
48PAK41.22515918
49BMPR21.22404444
50KSR11.20239691
51ACVR1B1.19282793
52MAP3K81.19071308
53MELK1.17721272
54MAP4K11.17481208
55PASK1.17138533
56PIM11.15972026
57STK41.15725484
58EPHA21.14057282
59KIT1.12851648
60CDK31.11898796
61NEK91.11352807
62PDGFRA1.06775771
63EPHA31.06758821
64PNCK1.05979733
65MAPK71.05609014
66TAOK31.04116890
67CAMKK21.00560635
68IKBKE0.99664973
69IRAK40.97869674
70FES0.97828937
71SGK30.96940335
72CSF1R0.95380151
73CLK10.95088554
74AURKB0.93830484
75HIPK20.93631323
76SRPK10.93630435
77TESK20.92792103
78EIF2AK10.92358508
79CDK70.91824698
80ERN10.91805246
81ATR0.88956749
82TBK10.88478926
83LYN0.85820979
84MAP3K50.85700588
85NUAK10.85552362
86IRAK10.84440641
87MST40.83971135
88CDK90.82302377
89PAK20.81042510
90TLK10.79645749
91PLK10.78967257
92TTN0.78726913
93MAP3K40.77330660
94MKNK20.76755034
95KSR20.75756891
96EIF2AK30.71715105
97MATK0.71006802
98TEC0.69466560
99RIPK10.69313828
100DDR20.68787063
101DYRK1B0.68784849
102RET0.67813174
103DYRK1A0.67460743
104JAK10.67436910
105ALK0.67302165
106TTK0.66361785
107EIF2AK20.64840515
108PDGFRB0.63698606
109FGR0.63386265
110LCK0.63328776
111ERBB30.62479822
112HCK0.61454746
113CSK0.61328422
114GRK60.61292547
115PIK3CG0.60843051
116CSNK1G10.57713074
117IKBKB0.57653657
118CHEK10.57342449
119PLK30.57101205
120FGFR20.56594673
121CHUK0.55979889
122ITK0.55940688
123YES10.55235642
124PIM20.54260961
125ATM0.54127843
126RPS6KL10.53915294
127RPS6KC10.53915294
128TESK10.53852040
129JAK20.53791377
130MARK30.53550705
131MAP3K130.53271944
132CHEK20.52304001
133EGFR0.51633093
134FGFR40.51579886
135MAPK100.50224402
136NLK0.49039442
137RPS6KB10.47760945
138KDR0.47525208
139BMX0.46923515
140CDK20.46028184
141ILK0.45897113
142TRPM70.45815898
143SGK4940.45326354
144SGK2230.45326354
145MAP3K30.44855457
146CSNK1G20.42950888
147UHMK10.37089124
148STK38L0.36709097
149MOS0.36605253
150FYN0.36170383

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.62044272
2Cell cycle_Homo sapiens_hsa041102.20627640
3Mismatch repair_Homo sapiens_hsa034302.02112875
4Leishmaniasis_Homo sapiens_hsa051401.88862095
5Antigen processing and presentation_Homo sapiens_hsa046121.77946096
6Chronic myeloid leukemia_Homo sapiens_hsa052201.76049534
7RNA transport_Homo sapiens_hsa030131.71460455
8Ribosome_Homo sapiens_hsa030101.69649052
9Spliceosome_Homo sapiens_hsa030401.69512035
10Small cell lung cancer_Homo sapiens_hsa052221.66225409
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.61293760
12p53 signaling pathway_Homo sapiens_hsa041151.57002714
13Herpes simplex infection_Homo sapiens_hsa051681.55149660
14One carbon pool by folate_Homo sapiens_hsa006701.53650525
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.48863073
16B cell receptor signaling pathway_Homo sapiens_hsa046621.48726971
17MicroRNAs in cancer_Homo sapiens_hsa052061.47694818
18Viral carcinogenesis_Homo sapiens_hsa052031.42997263
19Systemic lupus erythematosus_Homo sapiens_hsa053221.42323687
20Long-term potentiation_Homo sapiens_hsa047201.38326970
21Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.36860678
22Osteoclast differentiation_Homo sapiens_hsa043801.36436805
23Legionellosis_Homo sapiens_hsa051341.35165094
24Toxoplasmosis_Homo sapiens_hsa051451.34562126
25Hepatitis B_Homo sapiens_hsa051611.34335270
26Measles_Homo sapiens_hsa051621.33765466
27Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.32917439
28Transcriptional misregulation in cancer_Homo sapiens_hsa052021.31275912
29Base excision repair_Homo sapiens_hsa034101.31015826
30mRNA surveillance pathway_Homo sapiens_hsa030151.27838803
31Pancreatic cancer_Homo sapiens_hsa052121.26840891
32Phosphatidylinositol signaling system_Homo sapiens_hsa040701.25369474
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.24323446
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.24263042
35Shigellosis_Homo sapiens_hsa051311.23964394
36Toll-like receptor signaling pathway_Homo sapiens_hsa046201.23228709
37Inositol phosphate metabolism_Homo sapiens_hsa005621.17515250
38Choline metabolism in cancer_Homo sapiens_hsa052311.17368135
39NOD-like receptor signaling pathway_Homo sapiens_hsa046211.16307665
40Viral myocarditis_Homo sapiens_hsa054161.15889800
41Long-term depression_Homo sapiens_hsa047301.12971692
42Apoptosis_Homo sapiens_hsa042101.12726803
43Glioma_Homo sapiens_hsa052141.12567409
44Proteoglycans in cancer_Homo sapiens_hsa052051.12463517
45Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.11784061
46HTLV-I infection_Homo sapiens_hsa051661.11216371
47Influenza A_Homo sapiens_hsa051641.09259047
48Acute myeloid leukemia_Homo sapiens_hsa052211.07763365
49Colorectal cancer_Homo sapiens_hsa052101.07604919
50Nucleotide excision repair_Homo sapiens_hsa034201.07310567
51Homologous recombination_Homo sapiens_hsa034401.05751269
52TNF signaling pathway_Homo sapiens_hsa046681.05733541
53Pertussis_Homo sapiens_hsa051331.05183476
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.04802074
55Primary immunodeficiency_Homo sapiens_hsa053401.04065402
56Intestinal immune network for IgA production_Homo sapiens_hsa046721.02417930
57Adherens junction_Homo sapiens_hsa045201.01999397
58Thyroid cancer_Homo sapiens_hsa052161.01370299
59Renin secretion_Homo sapiens_hsa049241.00836159
60Epstein-Barr virus infection_Homo sapiens_hsa051691.00815902
61Gap junction_Homo sapiens_hsa045401.00749957
62Prostate cancer_Homo sapiens_hsa052151.00563904
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99996739
64Renin-angiotensin system_Homo sapiens_hsa046140.99434572
65Malaria_Homo sapiens_hsa051440.98497615
66TGF-beta signaling pathway_Homo sapiens_hsa043500.97894285
67Non-small cell lung cancer_Homo sapiens_hsa052230.96903241
68Focal adhesion_Homo sapiens_hsa045100.95716365
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.95266676
70Platelet activation_Homo sapiens_hsa046110.94729437
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.93295383
72mTOR signaling pathway_Homo sapiens_hsa041500.93258005
73Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93189492
74Dorso-ventral axis formation_Homo sapiens_hsa043200.92916440
75Jak-STAT signaling pathway_Homo sapiens_hsa046300.92834007
76Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90194748
77Tuberculosis_Homo sapiens_hsa051520.90123725
78Hematopoietic cell lineage_Homo sapiens_hsa046400.88490700
79T cell receptor signaling pathway_Homo sapiens_hsa046600.88050959
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87799367
81Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.87270208
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.85425687
83Non-homologous end-joining_Homo sapiens_hsa034500.85350833
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.82923641
85ErbB signaling pathway_Homo sapiens_hsa040120.82694875
86Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81591968
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81365790
88RNA degradation_Homo sapiens_hsa030180.80797477
89Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.78580801
90Renal cell carcinoma_Homo sapiens_hsa052110.78343751
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78223812
92African trypanosomiasis_Homo sapiens_hsa051430.77684006
93Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77331515
94Hepatitis C_Homo sapiens_hsa051600.77279636
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77082471
96Melanoma_Homo sapiens_hsa052180.76932276
97Bladder cancer_Homo sapiens_hsa052190.76858028
98Pathways in cancer_Homo sapiens_hsa052000.76754856
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.76439711
100Endometrial cancer_Homo sapiens_hsa052130.75525853
101Phospholipase D signaling pathway_Homo sapiens_hsa040720.75465688
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.74010374
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73884658
104Allograft rejection_Homo sapiens_hsa053300.73695099
105Prolactin signaling pathway_Homo sapiens_hsa049170.73652123
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72499247
107HIF-1 signaling pathway_Homo sapiens_hsa040660.72480389
108ECM-receptor interaction_Homo sapiens_hsa045120.72378259
109Selenocompound metabolism_Homo sapiens_hsa004500.72002776
110Amoebiasis_Homo sapiens_hsa051460.71860154
111Notch signaling pathway_Homo sapiens_hsa043300.71338880
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.69640146
113Autoimmune thyroid disease_Homo sapiens_hsa053200.69624106
114Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.69519783
115FoxO signaling pathway_Homo sapiens_hsa040680.67839604
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.67063686
117Oocyte meiosis_Homo sapiens_hsa041140.66470459
118Salmonella infection_Homo sapiens_hsa051320.66053215
119Insulin signaling pathway_Homo sapiens_hsa049100.65603675
120Fanconi anemia pathway_Homo sapiens_hsa034600.65018561
121VEGF signaling pathway_Homo sapiens_hsa043700.64674661
122Chemokine signaling pathway_Homo sapiens_hsa040620.63889459
123Pyrimidine metabolism_Homo sapiens_hsa002400.62669212
124Hippo signaling pathway_Homo sapiens_hsa043900.62158855
125Rap1 signaling pathway_Homo sapiens_hsa040150.60985475
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60772786
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60660938
128Ras signaling pathway_Homo sapiens_hsa040140.60489025
129N-Glycan biosynthesis_Homo sapiens_hsa005100.60273960
130Graft-versus-host disease_Homo sapiens_hsa053320.59392161
131MAPK signaling pathway_Homo sapiens_hsa040100.56794472
132Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56224499
133Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54121736
134Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.53484116
135Taste transduction_Homo sapiens_hsa047420.53315443
136Regulation of autophagy_Homo sapiens_hsa041400.52965273
137Endocytosis_Homo sapiens_hsa041440.52788762
138Type II diabetes mellitus_Homo sapiens_hsa049300.50484380

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