

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.91568959 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.12320275 |
| 3 | cytidine catabolic process (GO:0006216) | 6.34105704 |
| 4 | cytidine deamination (GO:0009972) | 6.34105704 |
| 5 | cytidine metabolic process (GO:0046087) | 6.34105704 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.49966856 |
| 7 | cellular response to interleukin-15 (GO:0071350) | 4.77249147 |
| 8 | protein complex biogenesis (GO:0070271) | 4.65046952 |
| 9 | regulation of mitochondrial translation (GO:0070129) | 4.64814747 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.32321298 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.23573763 |
| 12 | cytochrome complex assembly (GO:0017004) | 4.16222513 |
| 13 | negative regulation by host of viral transcription (GO:0043922) | 4.10100276 |
| 14 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.01572381 |
| 15 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.99023183 |
| 16 | protein neddylation (GO:0045116) | 3.97371874 |
| 17 | proteasome assembly (GO:0043248) | 3.92818713 |
| 18 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.84306532 |
| 19 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.81158887 |
| 20 | base-excision repair, AP site formation (GO:0006285) | 3.80753007 |
| 21 | signal peptide processing (GO:0006465) | 3.76721297 |
| 22 | regulation of regulatory T cell differentiation (GO:0045589) | 3.68695977 |
| 23 | macrophage chemotaxis (GO:0048246) | 3.67862177 |
| 24 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.66848142 |
| 25 | glyoxylate metabolic process (GO:0046487) | 3.66605708 |
| 26 | regulation of immunoglobulin secretion (GO:0051023) | 3.62422251 |
| 27 | respiratory electron transport chain (GO:0022904) | 3.49328831 |
| 28 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.47415029 |
| 29 | electron transport chain (GO:0022900) | 3.45436278 |
| 30 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.44751772 |
| 31 | ATP synthesis coupled proton transport (GO:0015986) | 3.43194857 |
| 32 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.43194857 |
| 33 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.42944209 |
| 34 | cytolysis (GO:0019835) | 3.41199768 |
| 35 | protein deneddylation (GO:0000338) | 3.37371531 |
| 36 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.36643502 |
| 37 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.36643502 |
| 38 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.35327669 |
| 39 | pseudouridine synthesis (GO:0001522) | 3.34023301 |
| 40 | actin nucleation (GO:0045010) | 3.32627651 |
| 41 | response to interleukin-15 (GO:0070672) | 3.31958911 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.25248625 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.25248625 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.25248625 |
| 45 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.22271481 |
| 46 | adaptation of signaling pathway (GO:0023058) | 3.20353679 |
| 47 | positive regulation of defense response to virus by host (GO:0002230) | 3.17881139 |
| 48 | negative regulation of membrane potential (GO:0045837) | 3.14917994 |
| 49 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.12869163 |
| 50 | T cell migration (GO:0072678) | 3.12431035 |
| 51 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.08857486 |
| 52 | eosinophil chemotaxis (GO:0048245) | 3.08385477 |
| 53 | positive regulation of lymphocyte migration (GO:2000403) | 3.07675527 |
| 54 | positive regulation of interleukin-17 production (GO:0032740) | 3.05874630 |
| 55 | regulation of chronic inflammatory response (GO:0002676) | 3.04215732 |
| 56 | aldehyde catabolic process (GO:0046185) | 3.03833100 |
| 57 | negative regulation of stress fiber assembly (GO:0051497) | 3.03106918 |
| 58 | platelet dense granule organization (GO:0060155) | 2.99164838 |
| 59 | lymphocyte chemotaxis (GO:0048247) | 2.94214304 |
| 60 | iron-sulfur cluster assembly (GO:0016226) | 2.93832136 |
| 61 | metallo-sulfur cluster assembly (GO:0031163) | 2.93832136 |
| 62 | cobalamin metabolic process (GO:0009235) | 2.92729361 |
| 63 | S-adenosylmethionine metabolic process (GO:0046500) | 2.91344328 |
| 64 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.89241087 |
| 65 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.85897385 |
| 66 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.84408863 |
| 67 | positive regulation of macrophage differentiation (GO:0045651) | 2.82585132 |
| 68 | L-methionine salvage (GO:0071267) | 2.77822087 |
| 69 | L-methionine biosynthetic process (GO:0071265) | 2.77822087 |
| 70 | amino acid salvage (GO:0043102) | 2.77822087 |
| 71 | eosinophil migration (GO:0072677) | 2.77684289 |
| 72 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.76241716 |
| 73 | positive regulation of protein homooligomerization (GO:0032464) | 2.75027856 |
| 74 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.73512035 |
| 75 | protein import into peroxisome matrix (GO:0016558) | 2.70266596 |
| 76 | mannosylation (GO:0097502) | 2.69035291 |
| 77 | interferon-gamma production (GO:0032609) | 2.67535280 |
| 78 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.66932677 |
| 79 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.66850429 |
| 80 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.66283565 |
| 81 | ncRNA 3-end processing (GO:0043628) | 2.65956873 |
| 82 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.65634843 |
| 83 | positive regulation of protein homodimerization activity (GO:0090073) | 2.63502018 |
| 84 | behavioral response to nicotine (GO:0035095) | 2.63293512 |
| 85 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.59269194 |
| 86 | response to gravity (GO:0009629) | 2.58373495 |
| 87 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 2.56296126 |
| 88 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.55958832 |
| 89 | regulation of interleukin-8 secretion (GO:2000482) | 2.55895899 |
| 90 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.53962280 |
| 91 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.53961410 |
| 92 | deoxyribose phosphate catabolic process (GO:0046386) | 2.53184730 |
| 93 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.52458216 |
| 94 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.50804612 |
| 95 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.50804612 |
| 96 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.50804612 |
| 97 | negative regulation of viral genome replication (GO:0045071) | 2.49977977 |
| 98 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.49684125 |
| 99 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.49181379 |
| 100 | L-phenylalanine catabolic process (GO:0006559) | 2.49181379 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.96733540 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.06375263 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.51489768 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.41764071 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.29725312 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.28420655 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.27222676 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.58008614 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.54812223 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.41705634 |
| 11 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.38945566 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.35222067 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.33896245 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25301039 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.24503640 |
| 16 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.19898764 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.17484472 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04586002 |
| 19 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.02847983 |
| 20 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.97227225 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.95624655 |
| 22 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.90922627 |
| 23 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.75594432 |
| 24 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.69444670 |
| 25 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62408324 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59367127 |
| 27 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.55167999 |
| 28 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.54005616 |
| 29 | GATA3_26560356_Chip-Seq_TH2_Human | 1.50156019 |
| 30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.47067138 |
| 31 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.43313618 |
| 32 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.42968085 |
| 33 | MYB_26560356_Chip-Seq_TH2_Human | 1.38439035 |
| 34 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.37066046 |
| 35 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.36441174 |
| 36 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.35722008 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.34867985 |
| 38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.33093742 |
| 39 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.32681693 |
| 40 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.31797964 |
| 41 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31183401 |
| 42 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29349282 |
| 43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.28387610 |
| 44 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.26875263 |
| 45 | NCOR_22424771_ChIP-Seq_293T_Human | 1.25403221 |
| 46 | ERA_21632823_ChIP-Seq_H3396_Human | 1.23525756 |
| 47 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.23507972 |
| 48 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.23417423 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.22788970 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.20518341 |
| 51 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.20109933 |
| 52 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.19958685 |
| 53 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.19933019 |
| 54 | SOX2_21211035_ChIP-Seq_LN229_Human | 1.19705633 |
| 55 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.16478259 |
| 56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.15179772 |
| 57 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.14762929 |
| 58 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14533999 |
| 59 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.13475674 |
| 60 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12928523 |
| 61 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.12467026 |
| 62 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.12158638 |
| 63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.11568811 |
| 64 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.10925107 |
| 65 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.10901915 |
| 66 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.10617943 |
| 67 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.10302094 |
| 68 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10209846 |
| 69 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.09844795 |
| 70 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08196884 |
| 71 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.06441314 |
| 72 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.05845621 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05809606 |
| 74 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.05547652 |
| 75 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.04627584 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03147720 |
| 77 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.03126340 |
| 78 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.02743689 |
| 79 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.02602062 |
| 80 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.02507565 |
| 81 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00870038 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.00021498 |
| 83 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99707962 |
| 84 | P300_27268052_Chip-Seq_Bcells_Human | 0.98859189 |
| 85 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98744245 |
| 86 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97967200 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97967200 |
| 88 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.96884183 |
| 89 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.96781752 |
| 90 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.96766898 |
| 91 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.93958288 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 0.91815046 |
| 93 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91524470 |
| 94 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.91034234 |
| 95 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.90730455 |
| 96 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.89414000 |
| 97 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89175804 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88782085 |
| 99 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.88045889 |
| 100 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.86137371 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 5.19299846 |
| 2 | MP0005671_abnormal_response_to | 3.75439427 |
| 3 | MP0003011_delayed_dark_adaptation | 3.46322171 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 3.32946902 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.79122564 |
| 6 | MP0001853_heart_inflammation | 2.55932512 |
| 7 | MP0003806_abnormal_nucleotide_metabolis | 2.49606600 |
| 8 | MP0002736_abnormal_nociception_after | 2.38469689 |
| 9 | MP0001905_abnormal_dopamine_level | 2.14271845 |
| 10 | MP0005377_hearing/vestibular/ear_phenot | 2.10973689 |
| 11 | MP0003878_abnormal_ear_physiology | 2.10973689 |
| 12 | MP0002876_abnormal_thyroid_physiology | 2.06544585 |
| 13 | MP0001968_abnormal_touch/_nociception | 2.04901935 |
| 14 | MP0001661_extended_life_span | 2.03638641 |
| 15 | MP0009785_altered_susceptibility_to | 1.94932813 |
| 16 | MP0002102_abnormal_ear_morphology | 1.93671627 |
| 17 | MP0003866_abnormal_defecation | 1.84299905 |
| 18 | MP0003786_premature_aging | 1.82912179 |
| 19 | MP0002277_abnormal_respiratory_mucosa | 1.81750267 |
| 20 | MP0004145_abnormal_muscle_electrophysio | 1.81489488 |
| 21 | MP0003122_maternal_imprinting | 1.76095521 |
| 22 | MP0000604_amyloidosis | 1.74017356 |
| 23 | MP0001502_abnormal_circadian_rhythm | 1.69684913 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 1.67597192 |
| 25 | MP0004742_abnormal_vestibular_system | 1.61284406 |
| 26 | MP0005000_abnormal_immune_tolerance | 1.56853653 |
| 27 | MP0003195_calcinosis | 1.52861656 |
| 28 | MP0004147_increased_porphyrin_level | 1.48634666 |
| 29 | MP0003880_abnormal_central_pattern | 1.47819331 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.44922397 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.44434034 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.41926800 |
| 33 | MP0002006_tumorigenesis | 1.40437697 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.39173867 |
| 35 | MP0003252_abnormal_bile_duct | 1.38366663 |
| 36 | MP0001984_abnormal_olfaction | 1.36970926 |
| 37 | MP0005025_abnormal_response_to | 1.36301917 |
| 38 | MP0006082_CNS_inflammation | 1.33326652 |
| 39 | MP0005408_hypopigmentation | 1.32738620 |
| 40 | MP0001800_abnormal_humoral_immune | 1.31201483 |
| 41 | MP0010386_abnormal_urinary_bladder | 1.27606237 |
| 42 | MP0001790_abnormal_immune_system | 1.27310163 |
| 43 | MP0005387_immune_system_phenotype | 1.27310163 |
| 44 | MP0000685_abnormal_immune_system | 1.24468587 |
| 45 | MP0002693_abnormal_pancreas_physiology | 1.21493187 |
| 46 | MP0005670_abnormal_white_adipose | 1.21308493 |
| 47 | MP0005646_abnormal_pituitary_gland | 1.20662933 |
| 48 | MP0001501_abnormal_sleep_pattern | 1.18124150 |
| 49 | MP0009046_muscle_twitch | 1.17757310 |
| 50 | MP0008872_abnormal_physiological_respon | 1.17558474 |
| 51 | MP0005645_abnormal_hypothalamus_physiol | 1.16773265 |
| 52 | MP0004133_heterotaxia | 1.16232604 |
| 53 | MP0001764_abnormal_homeostasis | 1.14379678 |
| 54 | MP0002928_abnormal_bile_duct | 1.11938569 |
| 55 | MP0002420_abnormal_adaptive_immunity | 1.11634940 |
| 56 | MP0009764_decreased_sensitivity_to | 1.10753231 |
| 57 | MP0005332_abnormal_amino_acid | 1.10316952 |
| 58 | MP0008775_abnormal_heart_ventricle | 1.09052405 |
| 59 | MP0002751_abnormal_autonomic_nervous | 1.08518548 |
| 60 | MP0001819_abnormal_immune_cell | 1.07626902 |
| 61 | MP0001727_abnormal_embryo_implantation | 1.05078534 |
| 62 | MP0002723_abnormal_immune_serum | 1.04901255 |
| 63 | MP0002272_abnormal_nervous_system | 1.02170020 |
| 64 | MP0006072_abnormal_retinal_apoptosis | 1.01657311 |
| 65 | MP0003763_abnormal_thymus_physiology | 1.00368117 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 0.99661410 |
| 67 | MP0000538_abnormal_urinary_bladder | 0.98906453 |
| 68 | MP0005058_abnormal_lysosome_morphology | 0.98672821 |
| 69 | MP0001756_abnormal_urination | 0.97643167 |
| 70 | MP0004130_abnormal_muscle_cell | 0.94017191 |
| 71 | MP0003136_yellow_coat_color | 0.91907745 |
| 72 | MP0009745_abnormal_behavioral_response | 0.91822768 |
| 73 | MP0000569_abnormal_digit_pigmentation | 0.91102125 |
| 74 | MP0001845_abnormal_inflammatory_respons | 0.89312900 |
| 75 | MP0006036_abnormal_mitochondrial_physio | 0.89194719 |
| 76 | MP0001765_abnormal_ion_homeostasis | 0.87324595 |
| 77 | MP0000639_abnormal_adrenal_gland | 0.85858439 |
| 78 | MP0004924_abnormal_behavior | 0.83769617 |
| 79 | MP0005386_behavior/neurological_phenoty | 0.83769617 |
| 80 | MP0005253_abnormal_eye_physiology | 0.83268316 |
| 81 | MP0000716_abnormal_immune_system | 0.81851154 |
| 82 | MP0002138_abnormal_hepatobiliary_system | 0.81279431 |
| 83 | MP0006276_abnormal_autonomic_nervous | 0.80303947 |
| 84 | MP0002452_abnormal_antigen_presenting | 0.78784532 |
| 85 | MP0005085_abnormal_gallbladder_physiolo | 0.78507639 |
| 86 | MP0003638_abnormal_response/metabolism_ | 0.76471717 |
| 87 | MP0002398_abnormal_bone_marrow | 0.76033380 |
| 88 | MP0000689_abnormal_spleen_morphology | 0.75800192 |
| 89 | MP0001963_abnormal_hearing_physiology | 0.75689522 |
| 90 | MP0002735_abnormal_chemical_nociception | 0.74520512 |
| 91 | MP0009643_abnormal_urine_homeostasis | 0.73575789 |
| 92 | MP0002405_respiratory_system_inflammati | 0.73199537 |
| 93 | MP0003448_altered_tumor_morphology | 0.72991269 |
| 94 | MP0003567_abnormal_fetal_cardiomyocyte | 0.72186525 |
| 95 | MP0002234_abnormal_pharynx_morphology | 0.71900226 |
| 96 | MP0005410_abnormal_fertilization | 0.71823473 |
| 97 | MP0001970_abnormal_pain_threshold | 0.71580077 |
| 98 | MP0001529_abnormal_vocalization | 0.70676170 |
| 99 | MP0000230_abnormal_systemic_arterial | 0.69102863 |
| 100 | MP0008873_increased_physiological_sensi | 0.69079451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cutaneous melanoma (HP:0012056) | 7.00670652 |
| 2 | Methylmalonic aciduria (HP:0012120) | 4.72004432 |
| 3 | Methylmalonic acidemia (HP:0002912) | 4.25542519 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.17352630 |
| 5 | Aplastic anemia (HP:0001915) | 4.16281036 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.92048666 |
| 7 | Stomatitis (HP:0010280) | 3.89687573 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.88068276 |
| 9 | Hyperglycinemia (HP:0002154) | 3.87304432 |
| 10 | Acute encephalopathy (HP:0006846) | 3.78958359 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.73492788 |
| 12 | IgG deficiency (HP:0004315) | 3.63645435 |
| 13 | Increased CSF lactate (HP:0002490) | 3.45464958 |
| 14 | Meningioma (HP:0002858) | 3.36273215 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.31667922 |
| 16 | Cerebral edema (HP:0002181) | 3.27163624 |
| 17 | Hypoproteinemia (HP:0003075) | 3.19137582 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.15890056 |
| 19 | Dicarboxylic aciduria (HP:0003215) | 3.15764063 |
| 20 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 3.15764063 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.10997755 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.06355818 |
| 23 | Hepatic necrosis (HP:0002605) | 3.04110692 |
| 24 | Ketosis (HP:0001946) | 2.98926304 |
| 25 | Increased intramyocellular lipid droplets (HP:0012240) | 2.95034994 |
| 26 | Pancytopenia (HP:0001876) | 2.92464903 |
| 27 | Abnormality of T cells (HP:0002843) | 2.90469305 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.90110906 |
| 29 | T lymphocytopenia (HP:0005403) | 2.74787882 |
| 30 | Thyroiditis (HP:0100646) | 2.67201285 |
| 31 | Lethargy (HP:0001254) | 2.66447303 |
| 32 | Chronic diarrhea (HP:0002028) | 2.64817201 |
| 33 | Optic disc pallor (HP:0000543) | 2.63019793 |
| 34 | Hypoalbuminemia (HP:0003073) | 2.52706324 |
| 35 | Abnormal albumin level (HP:0012116) | 2.52706324 |
| 36 | Abnormality of T cell physiology (HP:0011840) | 2.52042719 |
| 37 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.51280459 |
| 38 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.51280459 |
| 39 | Severe combined immunodeficiency (HP:0004430) | 2.48713815 |
| 40 | Lactic acidosis (HP:0003128) | 2.45960720 |
| 41 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.42047092 |
| 42 | Increased hepatocellular lipid droplets (HP:0006565) | 2.41504710 |
| 43 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.40318916 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.39726076 |
| 45 | Abnormality of T cell number (HP:0011839) | 2.37930166 |
| 46 | Abnormality of serum amino acid levels (HP:0003112) | 2.37428873 |
| 47 | Increased muscle lipid content (HP:0009058) | 2.34024892 |
| 48 | Spastic paraparesis (HP:0002313) | 2.33171820 |
| 49 | Type I transferrin isoform profile (HP:0003642) | 2.31063090 |
| 50 | Abnormality of vitamin B metabolism (HP:0004340) | 2.29279334 |
| 51 | Respiratory failure (HP:0002878) | 2.29204430 |
| 52 | Increased serum lactate (HP:0002151) | 2.28391339 |
| 53 | Abnormality of alanine metabolism (HP:0010916) | 2.27189008 |
| 54 | Hyperalaninemia (HP:0003348) | 2.27189008 |
| 55 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.27189008 |
| 56 | Renal Fanconi syndrome (HP:0001994) | 2.26266476 |
| 57 | Abnormality of glycine metabolism (HP:0010895) | 2.26091550 |
| 58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.26091550 |
| 59 | Ketoacidosis (HP:0001993) | 2.23319700 |
| 60 | Congenital stationary night blindness (HP:0007642) | 2.21859340 |
| 61 | Melanoma (HP:0002861) | 2.21066326 |
| 62 | Hemiplegia (HP:0002301) | 2.19391476 |
| 63 | Lipid accumulation in hepatocytes (HP:0006561) | 2.12913090 |
| 64 | Agitation (HP:0000713) | 2.12635402 |
| 65 | Pancreatic fibrosis (HP:0100732) | 2.06697236 |
| 66 | Panhypogammaglobulinemia (HP:0003139) | 2.04067988 |
| 67 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.01374836 |
| 68 | Type 2 muscle fiber atrophy (HP:0003554) | 2.00752482 |
| 69 | Leukodystrophy (HP:0002415) | 1.99840919 |
| 70 | Abnormal drinking behavior (HP:0030082) | 1.99662393 |
| 71 | Polydipsia (HP:0001959) | 1.99662393 |
| 72 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.99260852 |
| 73 | Cerebral palsy (HP:0100021) | 1.95540678 |
| 74 | Pancreatic cysts (HP:0001737) | 1.93961030 |
| 75 | Neoplasm of the lung (HP:0100526) | 1.93345877 |
| 76 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91225375 |
| 77 | IgM deficiency (HP:0002850) | 1.91078184 |
| 78 | Encephalitis (HP:0002383) | 1.89713784 |
| 79 | Emotional lability (HP:0000712) | 1.89633395 |
| 80 | Hyperammonemia (HP:0001987) | 1.87407407 |
| 81 | Renal cortical cysts (HP:0000803) | 1.85911532 |
| 82 | Increased IgM level (HP:0003496) | 1.85090529 |
| 83 | Abnormal protein glycosylation (HP:0012346) | 1.84443035 |
| 84 | Abnormal glycosylation (HP:0012345) | 1.84443035 |
| 85 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.84443035 |
| 86 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.84443035 |
| 87 | Abnormality of midbrain morphology (HP:0002418) | 1.81341317 |
| 88 | Molar tooth sign on MRI (HP:0002419) | 1.81341317 |
| 89 | Constricted visual fields (HP:0001133) | 1.80956322 |
| 90 | Abolished electroretinogram (ERG) (HP:0000550) | 1.80091562 |
| 91 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79051515 |
| 92 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.78571320 |
| 93 | Neoplasm of the adrenal gland (HP:0100631) | 1.78241334 |
| 94 | Combined immunodeficiency (HP:0005387) | 1.78002661 |
| 95 | Acute hepatic failure (HP:0006554) | 1.77794405 |
| 96 | Exercise intolerance (HP:0003546) | 1.77735974 |
| 97 | Abnormality of methionine metabolism (HP:0010901) | 1.75704496 |
| 98 | True hermaphroditism (HP:0010459) | 1.75409032 |
| 99 | Hypomagnesemia (HP:0002917) | 1.75013678 |
| 100 | Neoplasm of the respiratory system (HP:0100606) | 1.73495554 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 5.32034053 |
| 2 | TXK | 4.38117221 |
| 3 | KDR | 3.67490664 |
| 4 | FRK | 3.49425690 |
| 5 | ZAK | 3.46263808 |
| 6 | MAP4K2 | 3.43111342 |
| 7 | TLK1 | 3.42467649 |
| 8 | TESK2 | 3.02265905 |
| 9 | ITK | 2.17250797 |
| 10 | PDK2 | 2.10379131 |
| 11 | SCYL2 | 2.08307364 |
| 12 | WNK4 | 1.92297277 |
| 13 | GRK1 | 1.89581940 |
| 14 | MAPKAPK3 | 1.84709222 |
| 15 | FES | 1.84442450 |
| 16 | TESK1 | 1.75066416 |
| 17 | LIMK1 | 1.74841435 |
| 18 | PINK1 | 1.54663263 |
| 19 | VRK2 | 1.54553673 |
| 20 | TNK2 | 1.53694470 |
| 21 | ADRBK2 | 1.44927790 |
| 22 | NUAK1 | 1.39328835 |
| 23 | PIK3CG | 1.39068362 |
| 24 | TEC | 1.29569011 |
| 25 | PRKCQ | 1.28661848 |
| 26 | CSNK1G3 | 1.28050487 |
| 27 | MYLK | 1.24702752 |
| 28 | VRK1 | 1.20240410 |
| 29 | TAOK3 | 1.11225765 |
| 30 | IKBKB | 1.08536286 |
| 31 | RPS6KA5 | 1.07040879 |
| 32 | MAP3K12 | 1.03470082 |
| 33 | DAPK1 | 1.00969645 |
| 34 | CSNK1G2 | 0.95995075 |
| 35 | LCK | 0.91729567 |
| 36 | MAP2K7 | 0.90572588 |
| 37 | NTRK1 | 0.88192145 |
| 38 | CAMKK2 | 0.88066429 |
| 39 | SYK | 0.86442736 |
| 40 | MAP4K1 | 0.85498321 |
| 41 | STK39 | 0.83998269 |
| 42 | EIF2AK3 | 0.83403893 |
| 43 | BTK | 0.82674029 |
| 44 | CSNK1G1 | 0.82101804 |
| 45 | MAP3K13 | 0.79785967 |
| 46 | CSK | 0.76040185 |
| 47 | DYRK2 | 0.75519719 |
| 48 | RPS6KA4 | 0.74926768 |
| 49 | LYN | 0.73062025 |
| 50 | BUB1 | 0.69960246 |
| 51 | OBSCN | 0.69911654 |
| 52 | OXSR1 | 0.69598040 |
| 53 | CSNK1A1L | 0.67894427 |
| 54 | INSRR | 0.67126730 |
| 55 | AURKA | 0.65267858 |
| 56 | MAPKAPK5 | 0.64336338 |
| 57 | NEK1 | 0.63789177 |
| 58 | FGFR2 | 0.58888781 |
| 59 | MATK | 0.58847802 |
| 60 | TSSK6 | 0.58399614 |
| 61 | PLK4 | 0.58259343 |
| 62 | WNK3 | 0.58216641 |
| 63 | MST4 | 0.57734973 |
| 64 | MAP2K6 | 0.57599919 |
| 65 | ILK | 0.56302644 |
| 66 | IGF1R | 0.55827051 |
| 67 | CSNK1A1 | 0.51696531 |
| 68 | PASK | 0.49893816 |
| 69 | NTRK2 | 0.49408470 |
| 70 | SRPK1 | 0.49332458 |
| 71 | PLK1 | 0.48791237 |
| 72 | PRKCA | 0.48093090 |
| 73 | KIT | 0.46919503 |
| 74 | JAK3 | 0.46357892 |
| 75 | PKN1 | 0.43456780 |
| 76 | CAMK2A | 0.43376678 |
| 77 | PLK3 | 0.43317272 |
| 78 | ROCK1 | 0.43111884 |
| 79 | LRRK2 | 0.42206135 |
| 80 | INSR | 0.42192323 |
| 81 | NEK2 | 0.41249091 |
| 82 | PAK4 | 0.39901939 |
| 83 | STK16 | 0.38843593 |
| 84 | EIF2AK1 | 0.38034097 |
| 85 | ADRBK1 | 0.37943927 |
| 86 | JAK1 | 0.37871376 |
| 87 | TAOK2 | 0.37259138 |
| 88 | MAPK13 | 0.36884972 |
| 89 | PRKACA | 0.36852520 |
| 90 | ABL2 | 0.36115522 |
| 91 | BMPR2 | 0.34721130 |
| 92 | CSNK2A1 | 0.34356448 |
| 93 | CDK3 | 0.34040454 |
| 94 | MAP3K11 | 0.33532921 |
| 95 | TIE1 | 0.33521761 |
| 96 | FYN | 0.32907916 |
| 97 | BRSK1 | 0.32758947 |
| 98 | CSNK2A2 | 0.32089007 |
| 99 | ERBB2 | 0.28488099 |
| 100 | CAMKK1 | 0.28226146 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.99983570 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.87345429 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.60160772 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.08344582 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.97512852 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.76831324 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.75140024 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.62828803 |
| 9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.48684838 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.39972007 |
| 11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.11632132 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.08991527 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.95220070 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.84727227 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.82147800 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.76732930 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.72221361 |
| 18 | Ribosome_Homo sapiens_hsa03010 | 1.70906129 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.70458980 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.68324621 |
| 21 | Asthma_Homo sapiens_hsa05310 | 1.66600775 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.66346074 |
| 23 | Peroxisome_Homo sapiens_hsa04146 | 1.65696490 |
| 24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.65137383 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.54207687 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.50595640 |
| 27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.47924318 |
| 28 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.45935225 |
| 29 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.34659926 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.32535657 |
| 31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.30252190 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.29588366 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.19930204 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.19209337 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17772508 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15773001 |
| 37 | Phototransduction_Homo sapiens_hsa04744 | 1.15206601 |
| 38 | Retinol metabolism_Homo sapiens_hsa00830 | 1.08514820 |
| 39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.04593390 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04253750 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.93813365 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.93553816 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90312675 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.86827594 |
| 45 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.86809085 |
| 46 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.85695380 |
| 47 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.77147265 |
| 48 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75253006 |
| 49 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.75045677 |
| 50 | DNA replication_Homo sapiens_hsa03030 | 0.73191847 |
| 51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.71660569 |
| 52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69749029 |
| 53 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69150455 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67782336 |
| 55 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.66445002 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65910397 |
| 57 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.65646348 |
| 58 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.65421133 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.64945105 |
| 60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.64461941 |
| 61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.61928722 |
| 62 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61581419 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61205044 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59024244 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.58764390 |
| 66 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.58470421 |
| 67 | Malaria_Homo sapiens_hsa05144 | 0.58031448 |
| 68 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56422164 |
| 69 | Base excision repair_Homo sapiens_hsa03410 | 0.55701719 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.52201053 |
| 71 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.52162392 |
| 72 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50844184 |
| 73 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.50515043 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.50161449 |
| 75 | Salmonella infection_Homo sapiens_hsa05132 | 0.49510541 |
| 76 | RNA degradation_Homo sapiens_hsa03018 | 0.47478059 |
| 77 | Purine metabolism_Homo sapiens_hsa00230 | 0.46990869 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.41961359 |
| 79 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.37356534 |
| 80 | Shigellosis_Homo sapiens_hsa05131 | 0.34439047 |
| 81 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.34262944 |
| 82 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.33984936 |
| 83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.32991391 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29989316 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.29820618 |
| 86 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.29494798 |
| 87 | Homologous recombination_Homo sapiens_hsa03440 | 0.29417326 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29309106 |
| 89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.28352251 |
| 90 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.27388996 |
| 91 | Spliceosome_Homo sapiens_hsa03040 | 0.26329654 |
| 92 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25873521 |
| 93 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.25017537 |
| 94 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.23675127 |
| 95 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23507014 |
| 96 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.23475887 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.22936532 |
| 98 | Mismatch repair_Homo sapiens_hsa03430 | 0.22772041 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22684705 |
| 100 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.21337727 |

