

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | signal peptide processing (GO:0006465) | 7.71063521 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.01616617 |
| 3 | DNA deamination (GO:0045006) | 5.89885858 |
| 4 | sequestering of actin monomers (GO:0042989) | 5.42137156 |
| 5 | valine metabolic process (GO:0006573) | 5.28825170 |
| 6 | protein prenylation (GO:0018342) | 5.27963961 |
| 7 | prenylation (GO:0097354) | 5.27963961 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.23041568 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 5.23041568 |
| 10 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.95397546 |
| 11 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.95397546 |
| 12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.94404183 |
| 13 | cytidine metabolic process (GO:0046087) | 4.80463517 |
| 14 | cytidine catabolic process (GO:0006216) | 4.80463517 |
| 15 | cytidine deamination (GO:0009972) | 4.80463517 |
| 16 | macroautophagy (GO:0016236) | 4.72316171 |
| 17 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.57737486 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.36094542 |
| 19 | viral transcription (GO:0019083) | 4.26663562 |
| 20 | respiratory electron transport chain (GO:0022904) | 4.25405265 |
| 21 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.21133854 |
| 22 | protein complex biogenesis (GO:0070271) | 4.16578252 |
| 23 | electron transport chain (GO:0022900) | 4.15768142 |
| 24 | translational termination (GO:0006415) | 4.15107946 |
| 25 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.11348694 |
| 26 | regulation of translation in response to stress (GO:0043555) | 4.00854488 |
| 27 | protein targeting to ER (GO:0045047) | 3.99158154 |
| 28 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.99063294 |
| 29 | mitochondrion transport along microtubule (GO:0047497) | 3.99063294 |
| 30 | branched-chain amino acid catabolic process (GO:0009083) | 3.97162327 |
| 31 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.96496523 |
| 32 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.96028466 |
| 33 | sulfur amino acid catabolic process (GO:0000098) | 3.95821119 |
| 34 | cotranslational protein targeting to membrane (GO:0006613) | 3.95337331 |
| 35 | behavioral response to nicotine (GO:0035095) | 3.92847520 |
| 36 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.80681291 |
| 37 | establishment of mitochondrion localization (GO:0051654) | 3.80348866 |
| 38 | protein localization to endoplasmic reticulum (GO:0070972) | 3.78800108 |
| 39 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.77799085 |
| 40 | translational elongation (GO:0006414) | 3.69194522 |
| 41 | L-methionine salvage (GO:0071267) | 3.69135622 |
| 42 | L-methionine biosynthetic process (GO:0071265) | 3.69135622 |
| 43 | amino acid salvage (GO:0043102) | 3.69135622 |
| 44 | mannosylation (GO:0097502) | 3.66848841 |
| 45 | protein neddylation (GO:0045116) | 3.61486160 |
| 46 | ribosomal large subunit biogenesis (GO:0042273) | 3.43689797 |
| 47 | ribosomal small subunit biogenesis (GO:0042274) | 3.43071554 |
| 48 | rRNA methylation (GO:0031167) | 3.40706054 |
| 49 | cardiovascular system development (GO:0072358) | 3.36084398 |
| 50 | rRNA modification (GO:0000154) | 3.34997134 |
| 51 | seminiferous tubule development (GO:0072520) | 3.33911379 |
| 52 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.28527349 |
| 53 | NADH dehydrogenase complex assembly (GO:0010257) | 3.28527349 |
| 54 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.28527349 |
| 55 | L-fucose catabolic process (GO:0042355) | 3.26909610 |
| 56 | fucose catabolic process (GO:0019317) | 3.26909610 |
| 57 | L-fucose metabolic process (GO:0042354) | 3.26909610 |
| 58 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.23269636 |
| 59 | oxidative phosphorylation (GO:0006119) | 3.19037304 |
| 60 | cellular protein complex disassembly (GO:0043624) | 3.18070315 |
| 61 | chaperone-mediated protein transport (GO:0072321) | 3.18022911 |
| 62 | viral life cycle (GO:0019058) | 3.17219662 |
| 63 | regulation of regulatory T cell differentiation (GO:0045589) | 3.16210229 |
| 64 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.14997352 |
| 65 | RNA destabilization (GO:0050779) | 3.14705465 |
| 66 | GTP biosynthetic process (GO:0006183) | 3.12753313 |
| 67 | branched-chain amino acid metabolic process (GO:0009081) | 3.07464787 |
| 68 | cytochrome complex assembly (GO:0017004) | 3.06332836 |
| 69 | base-excision repair, AP site formation (GO:0006285) | 3.05866918 |
| 70 | ribosomal small subunit assembly (GO:0000028) | 3.03612099 |
| 71 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.03290770 |
| 72 | cellular response to interferon-beta (GO:0035458) | 3.01298452 |
| 73 | regulation of chronic inflammatory response (GO:0002676) | 3.00466517 |
| 74 | regulation of interleukin-8 secretion (GO:2000482) | 2.97658889 |
| 75 | intracellular protein transmembrane import (GO:0044743) | 2.96873231 |
| 76 | maturation of 5.8S rRNA (GO:0000460) | 2.94605502 |
| 77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.92404953 |
| 78 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.92404953 |
| 79 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.91149621 |
| 80 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.91078634 |
| 81 | actin nucleation (GO:0045010) | 2.91038961 |
| 82 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.90750296 |
| 83 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.90750296 |
| 84 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.90750296 |
| 85 | maturation of SSU-rRNA (GO:0030490) | 2.88470796 |
| 86 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.88284801 |
| 87 | positive regulation of defense response to virus by host (GO:0002230) | 2.87910162 |
| 88 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.87718530 |
| 89 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.86323512 |
| 90 | cytokinetic process (GO:0032506) | 2.84453702 |
| 91 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.83539509 |
| 92 | hydrogen ion transmembrane transport (GO:1902600) | 2.82230781 |
| 93 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.82084883 |
| 94 | translational initiation (GO:0006413) | 2.81742345 |
| 95 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.78556007 |
| 96 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.78556007 |
| 97 | ATP biosynthetic process (GO:0006754) | 2.77977259 |
| 98 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.77334911 |
| 99 | interferon-gamma production (GO:0032609) | 2.75737563 |
| 100 | auditory behavior (GO:0031223) | 2.73085386 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.58280429 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.23616811 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.63667833 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.53241660 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.47766170 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.45796892 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.27563469 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.26578860 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.13939089 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.91977695 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.79988783 |
| 12 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.71651957 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.32854648 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.31313413 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.26224745 |
| 16 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.22720070 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.19153834 |
| 18 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11140292 |
| 19 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.02034089 |
| 20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.99715021 |
| 21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.96940148 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.87291374 |
| 23 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.83464068 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.81264599 |
| 25 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.72259291 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.68994286 |
| 27 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.61461698 |
| 28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.59028300 |
| 29 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.49846781 |
| 30 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.49845842 |
| 31 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.48801867 |
| 32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.48331638 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45414426 |
| 34 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.44880277 |
| 35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.43813648 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.43118631 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.40044967 |
| 38 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.38108551 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37820461 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.36652472 |
| 41 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.33442483 |
| 42 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.30356022 |
| 43 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.30332090 |
| 44 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.30332090 |
| 45 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26813383 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.26576156 |
| 47 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.24624613 |
| 48 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.24373090 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.20791955 |
| 50 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.20403822 |
| 51 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19373899 |
| 52 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.17321286 |
| 53 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.15927060 |
| 54 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.15816346 |
| 55 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15773951 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.15650822 |
| 57 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15417358 |
| 58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.13497590 |
| 59 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13299395 |
| 60 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12922301 |
| 61 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12922301 |
| 62 | EWS_26573619_Chip-Seq_HEK293_Human | 1.11159687 |
| 63 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09316232 |
| 64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.07892340 |
| 65 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.06633759 |
| 66 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.06089270 |
| 67 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.06060296 |
| 68 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.05575347 |
| 69 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.03232884 |
| 70 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.02723169 |
| 71 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.02253190 |
| 72 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01335428 |
| 73 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.00633797 |
| 74 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.00497650 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.00114093 |
| 76 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.99570566 |
| 77 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.97597241 |
| 78 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.96661570 |
| 79 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.95900566 |
| 80 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.95635327 |
| 81 | ERA_21632823_ChIP-Seq_H3396_Human | 0.95273696 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94872273 |
| 83 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94714558 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94273219 |
| 85 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.94200214 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.93684744 |
| 87 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.92962874 |
| 88 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.91896045 |
| 89 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.91374297 |
| 90 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.90359576 |
| 91 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.90224898 |
| 92 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.89619289 |
| 93 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88369955 |
| 94 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87384735 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.87384735 |
| 96 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.85424416 |
| 97 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.84862405 |
| 98 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.82670160 |
| 99 | NCOR_22424771_ChIP-Seq_293T_Human | 0.82260637 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.81598188 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 7.24805024 |
| 2 | MP0003646_muscle_fatigue | 4.57076686 |
| 3 | MP0002822_catalepsy | 3.15121631 |
| 4 | MP0002638_abnormal_pupillary_reflex | 3.01553238 |
| 5 | MP0005671_abnormal_response_to | 2.63268005 |
| 6 | MP0005423_abnormal_somatic_nervous | 2.40339313 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.32870701 |
| 8 | MP0000569_abnormal_digit_pigmentation | 2.27005163 |
| 9 | MP0001529_abnormal_vocalization | 2.24089313 |
| 10 | MP0008058_abnormal_DNA_repair | 2.21123533 |
| 11 | MP0003880_abnormal_central_pattern | 2.14062137 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 2.01198512 |
| 13 | MP0001905_abnormal_dopamine_level | 1.96509750 |
| 14 | MP0002277_abnormal_respiratory_mucosa | 1.81391321 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.76549677 |
| 16 | MP0002234_abnormal_pharynx_morphology | 1.76090550 |
| 17 | MP0002938_white_spotting | 1.69313460 |
| 18 | MP0005623_abnormal_meninges_morphology | 1.59217601 |
| 19 | MP0002102_abnormal_ear_morphology | 1.56133860 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.55443980 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.54829139 |
| 22 | MP0002736_abnormal_nociception_after | 1.50222235 |
| 23 | MP0001919_abnormal_reproductive_system | 1.45342568 |
| 24 | MP0003136_yellow_coat_color | 1.45129734 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.37789955 |
| 26 | MP0003693_abnormal_embryo_hatching | 1.37636311 |
| 27 | MP0002095_abnormal_skin_pigmentation | 1.35738320 |
| 28 | MP0000750_abnormal_muscle_regeneration | 1.32028519 |
| 29 | MP0009785_altered_susceptibility_to | 1.29521440 |
| 30 | MP0000372_irregular_coat_pigmentation | 1.29145886 |
| 31 | MP0004742_abnormal_vestibular_system | 1.28801289 |
| 32 | MP0008872_abnormal_physiological_respon | 1.28236737 |
| 33 | MP0004142_abnormal_muscle_tone | 1.26705680 |
| 34 | MP0005397_hematopoietic_system_phenotyp | 1.24086612 |
| 35 | MP0001545_abnormal_hematopoietic_system | 1.24086612 |
| 36 | MP0009046_muscle_twitch | 1.20193302 |
| 37 | MP0009745_abnormal_behavioral_response | 1.19055425 |
| 38 | MP0001873_stomach_inflammation | 1.15674980 |
| 39 | MP0003011_delayed_dark_adaptation | 1.11912296 |
| 40 | MP0003137_abnormal_impulse_conducting | 1.10875679 |
| 41 | MP0004924_abnormal_behavior | 1.08503856 |
| 42 | MP0005386_behavior/neurological_phenoty | 1.08503856 |
| 43 | MP0003866_abnormal_defecation | 1.06514728 |
| 44 | MP0008789_abnormal_olfactory_epithelium | 1.05349048 |
| 45 | MP0008877_abnormal_DNA_methylation | 1.04842319 |
| 46 | MP0001485_abnormal_pinna_reflex | 1.01754186 |
| 47 | MP0005389_reproductive_system_phenotype | 1.01516991 |
| 48 | MP0000631_abnormal_neuroendocrine_gland | 1.00773748 |
| 49 | MP0002572_abnormal_emotion/affect_behav | 0.95607916 |
| 50 | MP0005636_abnormal_mineral_homeostasis | 0.95488239 |
| 51 | MP0004858_abnormal_nervous_system | 0.95314717 |
| 52 | MP0003718_maternal_effect | 0.95302482 |
| 53 | MP0006292_abnormal_olfactory_placode | 0.94830967 |
| 54 | MP0003195_calcinosis | 0.94826031 |
| 55 | MP0005646_abnormal_pituitary_gland | 0.93117732 |
| 56 | MP0004043_abnormal_pH_regulation | 0.93091540 |
| 57 | MP0001968_abnormal_touch/_nociception | 0.92756534 |
| 58 | MP0002272_abnormal_nervous_system | 0.92699757 |
| 59 | MP0003878_abnormal_ear_physiology | 0.92359094 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 0.92359094 |
| 61 | MP0004133_heterotaxia | 0.92066963 |
| 62 | MP0005195_abnormal_posterior_eye | 0.89438435 |
| 63 | MP0009250_abnormal_appendicular_skeleto | 0.88750750 |
| 64 | MP0009764_decreased_sensitivity_to | 0.87983989 |
| 65 | MP0002928_abnormal_bile_duct | 0.87329153 |
| 66 | MP0001790_abnormal_immune_system | 0.87171528 |
| 67 | MP0005387_immune_system_phenotype | 0.87171528 |
| 68 | MP0000566_synostosis | 0.86942329 |
| 69 | MP0008995_early_reproductive_senescence | 0.86657487 |
| 70 | MP0002163_abnormal_gland_morphology | 0.85231252 |
| 71 | MP0002067_abnormal_sensory_capabilities | 0.84175054 |
| 72 | MP0001501_abnormal_sleep_pattern | 0.82587112 |
| 73 | MP0001486_abnormal_startle_reflex | 0.82447359 |
| 74 | MP0008875_abnormal_xenobiotic_pharmacok | 0.81897439 |
| 75 | MP0005394_taste/olfaction_phenotype | 0.81168917 |
| 76 | MP0005499_abnormal_olfactory_system | 0.81168917 |
| 77 | MP0001188_hyperpigmentation | 0.80279316 |
| 78 | MP0002557_abnormal_social/conspecific_i | 0.77145396 |
| 79 | MP0003315_abnormal_perineum_morphology | 0.75802476 |
| 80 | MP0003786_premature_aging | 0.74192530 |
| 81 | MP0005253_abnormal_eye_physiology | 0.73725077 |
| 82 | MP0002909_abnormal_adrenal_gland | 0.73361228 |
| 83 | MP0002064_seizures | 0.72324422 |
| 84 | MP0005410_abnormal_fertilization | 0.71945346 |
| 85 | MP0009765_abnormal_xenobiotic_induced | 0.69925024 |
| 86 | MP0003698_abnormal_male_reproductive | 0.69579715 |
| 87 | MP0002210_abnormal_sex_determination | 0.69076150 |
| 88 | MP0002752_abnormal_somatic_nervous | 0.68879188 |
| 89 | MP0000026_abnormal_inner_ear | 0.68639857 |
| 90 | MP0002148_abnormal_hypersensitivity_rea | 0.67076696 |
| 91 | MP0003186_abnormal_redox_activity | 0.65100020 |
| 92 | MP0005379_endocrine/exocrine_gland_phen | 0.64660268 |
| 93 | MP0004147_increased_porphyrin_level | 0.64080232 |
| 94 | MP0002751_abnormal_autonomic_nervous | 0.61685436 |
| 95 | MP0006036_abnormal_mitochondrial_physio | 0.61435887 |
| 96 | MP0009053_abnormal_anal_canal | 0.61016841 |
| 97 | MP0002735_abnormal_chemical_nociception | 0.60710511 |
| 98 | MP0009333_abnormal_splenocyte_physiolog | 0.60565006 |
| 99 | MP0001119_abnormal_female_reproductive | 0.60401554 |
| 100 | MP0000534_abnormal_ureter_morphology | 0.60096612 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.81376325 |
| 2 | Pendular nystagmus (HP:0012043) | 4.79148373 |
| 3 | Decreased central vision (HP:0007663) | 4.69832213 |
| 4 | Type II lissencephaly (HP:0007260) | 4.48439258 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.42073896 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 4.27670933 |
| 7 | Retinal dysplasia (HP:0007973) | 4.23787759 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 4.08810794 |
| 9 | Acanthocytosis (HP:0001927) | 4.01549613 |
| 10 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.94667275 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.92797933 |
| 12 | Acute encephalopathy (HP:0006846) | 3.81199698 |
| 13 | Cerebral hypomyelination (HP:0006808) | 3.68173188 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.67621385 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.60794983 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.47399146 |
| 17 | Cerebellar dysplasia (HP:0007033) | 3.42422560 |
| 18 | Attenuation of retinal blood vessels (HP:0007843) | 3.38069097 |
| 19 | Increased CSF lactate (HP:0002490) | 3.36206615 |
| 20 | Personality changes (HP:0000751) | 3.29562218 |
| 21 | Disinhibition (HP:0000734) | 3.29225732 |
| 22 | Keratoconus (HP:0000563) | 3.24569128 |
| 23 | Increased corneal curvature (HP:0100692) | 3.24569128 |
| 24 | Increased intramyocellular lipid droplets (HP:0012240) | 3.19771032 |
| 25 | Hepatocellular necrosis (HP:0001404) | 3.09997177 |
| 26 | Acute hepatic failure (HP:0006554) | 2.98619271 |
| 27 | Renal cortical cysts (HP:0000803) | 2.97934917 |
| 28 | Retinal atrophy (HP:0001105) | 2.91866222 |
| 29 | Self-mutilation (HP:0000742) | 2.89363573 |
| 30 | Optic disc pallor (HP:0000543) | 2.87426659 |
| 31 | Hepatic necrosis (HP:0002605) | 2.86938463 |
| 32 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.84634533 |
| 33 | Lissencephaly (HP:0001339) | 2.81469962 |
| 34 | Agitation (HP:0000713) | 2.72119648 |
| 35 | True hermaphroditism (HP:0010459) | 2.72006540 |
| 36 | Delayed CNS myelination (HP:0002188) | 2.68933646 |
| 37 | CNS hypomyelination (HP:0003429) | 2.68549181 |
| 38 | Hypoplasia of the pons (HP:0012110) | 2.67329512 |
| 39 | Increased muscle lipid content (HP:0009058) | 2.67009639 |
| 40 | Abolished electroretinogram (ERG) (HP:0000550) | 2.64591929 |
| 41 | Abnormality of the pons (HP:0007361) | 2.64325215 |
| 42 | Exertional dyspnea (HP:0002875) | 2.63082145 |
| 43 | Cerebral edema (HP:0002181) | 2.62225469 |
| 44 | Nephronophthisis (HP:0000090) | 2.57133028 |
| 45 | Pancreatic cysts (HP:0001737) | 2.56776211 |
| 46 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.55032064 |
| 47 | Carpal bone hypoplasia (HP:0001498) | 2.52605235 |
| 48 | IgG deficiency (HP:0004315) | 2.45277337 |
| 49 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.45198096 |
| 50 | Dyskinesia (HP:0100660) | 2.42388133 |
| 51 | Pancreatic fibrosis (HP:0100732) | 2.38731978 |
| 52 | Abnormal drinking behavior (HP:0030082) | 2.38473426 |
| 53 | Polydipsia (HP:0001959) | 2.38473426 |
| 54 | Pallor (HP:0000980) | 2.38358348 |
| 55 | Anencephaly (HP:0002323) | 2.36875990 |
| 56 | Medial flaring of the eyebrow (HP:0010747) | 2.28833553 |
| 57 | Hyperphosphaturia (HP:0003109) | 2.28762071 |
| 58 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.27072049 |
| 59 | CNS demyelination (HP:0007305) | 2.25712301 |
| 60 | Abnormality of renal resorption (HP:0011038) | 2.23704763 |
| 61 | Abnormality of the renal cortex (HP:0011035) | 2.22210586 |
| 62 | Generalized aminoaciduria (HP:0002909) | 2.21082406 |
| 63 | Abnormality of midbrain morphology (HP:0002418) | 2.19812903 |
| 64 | Molar tooth sign on MRI (HP:0002419) | 2.19812903 |
| 65 | Choreoathetosis (HP:0001266) | 2.19564830 |
| 66 | Hyperglycinemia (HP:0002154) | 2.19484261 |
| 67 | Congenital, generalized hypertrichosis (HP:0004540) | 2.16138185 |
| 68 | Emotional lability (HP:0000712) | 2.10999486 |
| 69 | Severe muscular hypotonia (HP:0006829) | 2.10223518 |
| 70 | Aplastic anemia (HP:0001915) | 2.09787517 |
| 71 | Exercise intolerance (HP:0003546) | 2.08073590 |
| 72 | Respiratory failure (HP:0002878) | 2.05222111 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 2.04814023 |
| 74 | Glycosuria (HP:0003076) | 2.04814023 |
| 75 | Hypoplasia of the brainstem (HP:0002365) | 2.03641328 |
| 76 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.03641328 |
| 77 | Intellectual disability, profound (HP:0002187) | 2.03088129 |
| 78 | Pachygyria (HP:0001302) | 2.00643697 |
| 79 | Macular degeneration (HP:0000608) | 2.00488315 |
| 80 | Lethargy (HP:0001254) | 2.00212196 |
| 81 | Leukodystrophy (HP:0002415) | 1.95123768 |
| 82 | Increased serum lactate (HP:0002151) | 1.94033614 |
| 83 | Premature ovarian failure (HP:0008209) | 1.93091630 |
| 84 | Inappropriate behavior (HP:0000719) | 1.91732988 |
| 85 | Lactic acidosis (HP:0003128) | 1.91291769 |
| 86 | Unsteady gait (HP:0002317) | 1.88521460 |
| 87 | Brushfield spots (HP:0001088) | 1.88302293 |
| 88 | Hypothermia (HP:0002045) | 1.88251507 |
| 89 | Delusions (HP:0000746) | 1.87294980 |
| 90 | Abnormal albumin level (HP:0012116) | 1.85435312 |
| 91 | Hypoalbuminemia (HP:0003073) | 1.85435312 |
| 92 | Abnormality of the renal medulla (HP:0100957) | 1.84206470 |
| 93 | T lymphocytopenia (HP:0005403) | 1.83536390 |
| 94 | Decreased circulating renin level (HP:0003351) | 1.82219382 |
| 95 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.81721556 |
| 96 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.81604503 |
| 97 | Infantile muscular hypotonia (HP:0008947) | 1.80678069 |
| 98 | Limb hypertonia (HP:0002509) | 1.78517946 |
| 99 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.77324448 |
| 100 | Irregular epiphyses (HP:0010582) | 1.73185290 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME2 | 3.54796360 |
| 2 | TXK | 3.36839049 |
| 3 | WNK3 | 3.23676761 |
| 4 | MAP4K1 | 2.97654322 |
| 5 | KDR | 2.71085585 |
| 6 | VRK2 | 2.68661446 |
| 7 | MAPK15 | 2.12740140 |
| 8 | BCKDK | 2.11561273 |
| 9 | PNCK | 2.01359052 |
| 10 | TAF1 | 1.95168804 |
| 11 | MARK3 | 1.93551428 |
| 12 | WNK4 | 1.88352508 |
| 13 | VRK1 | 1.79167085 |
| 14 | MAP4K2 | 1.77132607 |
| 15 | STK10 | 1.72770226 |
| 16 | SRPK1 | 1.68514259 |
| 17 | TSSK6 | 1.63630980 |
| 18 | GRK1 | 1.54696244 |
| 19 | MAP3K11 | 1.54675477 |
| 20 | ZAK | 1.52163003 |
| 21 | RIPK4 | 1.52161187 |
| 22 | ADRBK2 | 1.49181401 |
| 23 | GRK6 | 1.47952432 |
| 24 | EPHA3 | 1.43813946 |
| 25 | TLK1 | 1.43145031 |
| 26 | NTRK2 | 1.42670601 |
| 27 | TNIK | 1.42483868 |
| 28 | WEE1 | 1.41635832 |
| 29 | BUB1 | 1.29733710 |
| 30 | MAPK13 | 1.24011555 |
| 31 | DYRK2 | 1.22699208 |
| 32 | BMPR2 | 1.17974731 |
| 33 | FRK | 1.16123512 |
| 34 | NME1 | 1.14382984 |
| 35 | INSRR | 1.13391056 |
| 36 | PASK | 1.09170898 |
| 37 | MAP3K12 | 1.07978968 |
| 38 | OBSCN | 1.03993289 |
| 39 | ITK | 1.01135114 |
| 40 | PIM1 | 0.99378299 |
| 41 | LRRK2 | 0.99134045 |
| 42 | MUSK | 0.98997888 |
| 43 | NUAK1 | 0.97782647 |
| 44 | TAOK3 | 0.96005554 |
| 45 | RPS6KA5 | 0.94013561 |
| 46 | PKN1 | 0.93014330 |
| 47 | SYK | 0.90668554 |
| 48 | MARK1 | 0.88204939 |
| 49 | MST4 | 0.88014590 |
| 50 | TESK2 | 0.86411515 |
| 51 | BMPR1B | 0.85596985 |
| 52 | GRK7 | 0.83740317 |
| 53 | STK16 | 0.83203615 |
| 54 | PINK1 | 0.82213921 |
| 55 | OXSR1 | 0.79211412 |
| 56 | GRK5 | 0.77448691 |
| 57 | CAMK2A | 0.75682432 |
| 58 | STK11 | 0.75431230 |
| 59 | STK39 | 0.74764935 |
| 60 | PRKCG | 0.72885205 |
| 61 | CSNK1G3 | 0.72470283 |
| 62 | PRKACA | 0.71911554 |
| 63 | TRIM28 | 0.69426419 |
| 64 | PIK3CA | 0.64789693 |
| 65 | TEC | 0.63140734 |
| 66 | MAP3K4 | 0.61740311 |
| 67 | PRKCQ | 0.61695338 |
| 68 | KIT | 0.61658228 |
| 69 | BCR | 0.60858987 |
| 70 | PLK3 | 0.58035547 |
| 71 | LCK | 0.57144973 |
| 72 | ACVR1B | 0.55434879 |
| 73 | PLK2 | 0.54217413 |
| 74 | CCNB1 | 0.53226648 |
| 75 | CSNK2A1 | 0.53177169 |
| 76 | MAPKAPK5 | 0.51484253 |
| 77 | CSNK1A1L | 0.50417563 |
| 78 | CSNK1G2 | 0.50210180 |
| 79 | CSNK1G1 | 0.50136549 |
| 80 | CSK | 0.49315931 |
| 81 | CAMK1 | 0.48752546 |
| 82 | ADRBK1 | 0.48635790 |
| 83 | PRKCE | 0.48268463 |
| 84 | BLK | 0.47578880 |
| 85 | TESK1 | 0.47357450 |
| 86 | TGFBR1 | 0.46186433 |
| 87 | CSNK2A2 | 0.45752195 |
| 88 | CSNK1A1 | 0.44109698 |
| 89 | MINK1 | 0.42943827 |
| 90 | PRKCA | 0.42124180 |
| 91 | PIM2 | 0.41962465 |
| 92 | PHKG1 | 0.41937974 |
| 93 | PHKG2 | 0.41937974 |
| 94 | DAPK2 | 0.40366448 |
| 95 | TIE1 | 0.39357898 |
| 96 | LIMK1 | 0.38986823 |
| 97 | NTRK3 | 0.38385450 |
| 98 | ABL2 | 0.38323248 |
| 99 | ERBB3 | 0.37604976 |
| 100 | AURKA | 0.37342349 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.70624927 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.10948219 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.91757613 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.70760910 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.05350538 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.63987365 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48683931 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.43374218 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.38373458 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.28034896 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.26674437 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.25760064 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25555355 |
| 14 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.03501533 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.83190344 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.81074358 |
| 17 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.57783000 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.45108562 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.39035727 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.33414616 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.29795149 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.28511335 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.26164339 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.24086596 |
| 25 | Peroxisome_Homo sapiens_hsa04146 | 1.21722891 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.15619089 |
| 27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.14738548 |
| 28 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.13565833 |
| 29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.10797397 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.09125666 |
| 31 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.07331080 |
| 32 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.05774362 |
| 33 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.05730351 |
| 34 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02304343 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.01262236 |
| 36 | Nicotine addiction_Homo sapiens_hsa05033 | 1.01046719 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.00602162 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.93139597 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90663649 |
| 40 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.90335463 |
| 41 | Olfactory transduction_Homo sapiens_hsa04740 | 0.88520352 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.85670925 |
| 43 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.84937406 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83726680 |
| 45 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.83266195 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.83262278 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.78171720 |
| 48 | Basal transcription factors_Homo sapiens_hsa03022 | 0.77263183 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.74749540 |
| 50 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.74010391 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72856047 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.70439938 |
| 53 | Asthma_Homo sapiens_hsa05310 | 0.68619492 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68317297 |
| 55 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.68260921 |
| 56 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.66144128 |
| 57 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.64519080 |
| 58 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.63258714 |
| 59 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63120195 |
| 60 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.62744272 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.60550589 |
| 62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.59969792 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.59441449 |
| 64 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.57414359 |
| 65 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.56019684 |
| 66 | Morphine addiction_Homo sapiens_hsa05032 | 0.55959965 |
| 67 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.55821710 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55818453 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55052188 |
| 70 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.54952065 |
| 71 | Insulin secretion_Homo sapiens_hsa04911 | 0.52576054 |
| 72 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.52389014 |
| 73 | Taste transduction_Homo sapiens_hsa04742 | 0.51248337 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.50473599 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47877471 |
| 76 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47400055 |
| 77 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.45630012 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.45173274 |
| 79 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.44289682 |
| 80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.43924280 |
| 81 | GABAergic synapse_Homo sapiens_hsa04727 | 0.43445165 |
| 82 | Cocaine addiction_Homo sapiens_hsa05030 | 0.43273081 |
| 83 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43193278 |
| 84 | ABC transporters_Homo sapiens_hsa02010 | 0.42816764 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41818834 |
| 86 | Phagosome_Homo sapiens_hsa04145 | 0.41596556 |
| 87 | Mismatch repair_Homo sapiens_hsa03430 | 0.39105030 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38480715 |
| 89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37982157 |
| 90 | Histidine metabolism_Homo sapiens_hsa00340 | 0.34739221 |
| 91 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.33222057 |
| 92 | DNA replication_Homo sapiens_hsa03030 | 0.33168574 |
| 93 | RNA transport_Homo sapiens_hsa03013 | 0.31157456 |
| 94 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30849733 |
| 95 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.30746441 |
| 96 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29730045 |
| 97 | Spliceosome_Homo sapiens_hsa03040 | 0.28560527 |
| 98 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.28558529 |
| 99 | Homologous recombination_Homo sapiens_hsa03440 | 0.27491311 |
| 100 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27421899 |

