

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.10862504 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.65869556 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.52268708 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 6.52268708 |
| 5 | chaperone-mediated protein transport (GO:0072321) | 6.17692776 |
| 6 | ribosomal small subunit biogenesis (GO:0042274) | 6.00275586 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.63093970 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.57532325 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 5.48858775 |
| 10 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.45051435 |
| 11 | respiratory electron transport chain (GO:0022904) | 5.41231672 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 5.37320366 |
| 13 | electron transport chain (GO:0022900) | 5.28596849 |
| 14 | cytidine deamination (GO:0009972) | 5.27961040 |
| 15 | cytidine metabolic process (GO:0046087) | 5.27961040 |
| 16 | cytidine catabolic process (GO:0006216) | 5.27961040 |
| 17 | viral transcription (GO:0019083) | 4.77716323 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.76529783 |
| 19 | translational termination (GO:0006415) | 4.57653270 |
| 20 | protein complex biogenesis (GO:0070271) | 4.52094177 |
| 21 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.37145857 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.35616404 |
| 23 | protein targeting to ER (GO:0045047) | 4.33431074 |
| 24 | cotranslational protein targeting to membrane (GO:0006613) | 4.30403790 |
| 25 | translational elongation (GO:0006414) | 4.30397435 |
| 26 | proteasome assembly (GO:0043248) | 4.29706747 |
| 27 | respiratory chain complex IV assembly (GO:0008535) | 4.18381784 |
| 28 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.17129408 |
| 29 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.13172586 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.13172586 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 4.13172586 |
| 32 | protein localization to endoplasmic reticulum (GO:0070972) | 4.10598797 |
| 33 | protein targeting to mitochondrion (GO:0006626) | 4.04967135 |
| 34 | ATP biosynthetic process (GO:0006754) | 3.99566857 |
| 35 | translation (GO:0006412) | 3.98462006 |
| 36 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.98406632 |
| 37 | establishment of protein localization to mitochondrion (GO:0072655) | 3.94764053 |
| 38 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.92388566 |
| 39 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.87285908 |
| 40 | cytochrome complex assembly (GO:0017004) | 3.85345250 |
| 41 | viral life cycle (GO:0019058) | 3.79719027 |
| 42 | hydrogen ion transmembrane transport (GO:1902600) | 3.78575896 |
| 43 | pseudouridine synthesis (GO:0001522) | 3.78370435 |
| 44 | cellular component biogenesis (GO:0044085) | 3.74401937 |
| 45 | GTP biosynthetic process (GO:0006183) | 3.69657312 |
| 46 | ubiquinone biosynthetic process (GO:0006744) | 3.69508526 |
| 47 | sequestering of actin monomers (GO:0042989) | 3.68720358 |
| 48 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.68310194 |
| 49 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.67857399 |
| 50 | protein localization to mitochondrion (GO:0070585) | 3.65728696 |
| 51 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.64376490 |
| 52 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.58749978 |
| 53 | translational initiation (GO:0006413) | 3.52286132 |
| 54 | regulation of mitochondrial translation (GO:0070129) | 3.51194512 |
| 55 | cellular protein complex disassembly (GO:0043624) | 3.49581571 |
| 56 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.46754039 |
| 57 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.46754039 |
| 58 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.46754039 |
| 59 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.46119346 |
| 60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.46119346 |
| 61 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.45744742 |
| 62 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.45744742 |
| 63 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.42628513 |
| 64 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.42514702 |
| 65 | proton transport (GO:0015992) | 3.42474256 |
| 66 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.37463004 |
| 67 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.37463004 |
| 68 | negative regulation of ligase activity (GO:0051352) | 3.36492786 |
| 69 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.36492786 |
| 70 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.34410236 |
| 71 | ubiquinone metabolic process (GO:0006743) | 3.34407827 |
| 72 | hydrogen transport (GO:0006818) | 3.34087399 |
| 73 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.33969577 |
| 74 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.33969577 |
| 75 | ribosomal large subunit biogenesis (GO:0042273) | 3.32835566 |
| 76 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.30156438 |
| 77 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.29678880 |
| 78 | rRNA modification (GO:0000154) | 3.28250069 |
| 79 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.25974478 |
| 80 | termination of RNA polymerase III transcription (GO:0006386) | 3.25974478 |
| 81 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.25292151 |
| 82 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.25222026 |
| 83 | behavioral response to nicotine (GO:0035095) | 3.19430667 |
| 84 | protein neddylation (GO:0045116) | 3.18636158 |
| 85 | cellular response to interferon-beta (GO:0035458) | 3.17119240 |
| 86 | mitochondrial transport (GO:0006839) | 3.14547038 |
| 87 | UTP biosynthetic process (GO:0006228) | 3.13971308 |
| 88 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.12383874 |
| 89 | rRNA processing (GO:0006364) | 3.08410395 |
| 90 | response to interferon-beta (GO:0035456) | 3.07630761 |
| 91 | ribosome biogenesis (GO:0042254) | 3.07160434 |
| 92 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.03424521 |
| 93 | rRNA metabolic process (GO:0016072) | 3.01383606 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.00191095 |
| 95 | signal peptide processing (GO:0006465) | 2.97582113 |
| 96 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.97305898 |
| 97 | quinone biosynthetic process (GO:1901663) | 2.96614691 |
| 98 | GPI anchor biosynthetic process (GO:0006506) | 2.96115916 |
| 99 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.95624174 |
| 100 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.94988886 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.85291454 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.52547586 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.31450038 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.03399940 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.49453276 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.47874130 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.34511255 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.19216751 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.16935131 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.06156908 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.05542615 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.89050170 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.84883057 |
| 14 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.70663495 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.64512191 |
| 16 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.57105070 |
| 17 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.48710365 |
| 18 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.45327875 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.44146428 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.43432171 |
| 21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.33257370 |
| 22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.30685989 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.28920224 |
| 24 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.08618067 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.96503792 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.93895050 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.89190427 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.84824190 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.79671495 |
| 30 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.79494325 |
| 31 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.78831429 |
| 32 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.72158601 |
| 33 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.72080306 |
| 34 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.72065712 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.67001212 |
| 36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.60687550 |
| 37 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.46365558 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.42741789 |
| 39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.40796299 |
| 40 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.40739489 |
| 41 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36675620 |
| 42 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.33727194 |
| 43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.33059737 |
| 44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.29850667 |
| 45 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29448519 |
| 46 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.29432533 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26149983 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.24191998 |
| 49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.23668108 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.22833229 |
| 51 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.22087703 |
| 52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.21796454 |
| 53 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.21198488 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.20277444 |
| 55 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.16888717 |
| 56 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16862334 |
| 57 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13856723 |
| 58 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.13458519 |
| 59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.13123207 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.10517495 |
| 61 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.08783627 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.08662267 |
| 63 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.07240284 |
| 64 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.05708410 |
| 65 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.05426275 |
| 66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.05015289 |
| 67 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.03261449 |
| 68 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01568214 |
| 69 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.01491649 |
| 70 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.01192914 |
| 71 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.99695006 |
| 72 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99327643 |
| 73 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.98995647 |
| 74 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98612103 |
| 75 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.98248076 |
| 76 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.95692969 |
| 77 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95315059 |
| 78 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.93948550 |
| 79 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93286077 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93286077 |
| 81 | VDR_22108803_ChIP-Seq_LS180_Human | 0.92650213 |
| 82 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.91682833 |
| 83 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.91591182 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.90917272 |
| 85 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90580477 |
| 86 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.89523271 |
| 87 | SA1_27219007_Chip-Seq_Bcells_Human | 0.88382338 |
| 88 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.88017362 |
| 89 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.87924890 |
| 90 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87882152 |
| 91 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.87674840 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.86439754 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.86384100 |
| 94 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.86136483 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.84443204 |
| 96 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.83467922 |
| 97 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.83029669 |
| 98 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.82342752 |
| 99 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.81544929 |
| 100 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.80921398 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002163_abnormal_gland_morphology | 4.34643667 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.59708876 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.45555079 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 2.94364271 |
| 5 | MP0004147_increased_porphyrin_level | 2.87587238 |
| 6 | MP0005379_endocrine/exocrine_gland_phen | 2.87090682 |
| 7 | MP0005671_abnormal_response_to | 2.82456080 |
| 8 | MP0003786_premature_aging | 2.57913576 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.51580752 |
| 10 | MP0003123_paternal_imprinting | 2.30453439 |
| 11 | MP0004145_abnormal_muscle_electrophysio | 2.19014809 |
| 12 | MP0001835_abnormal_antigen_presentation | 2.04134927 |
| 13 | MP0002166_altered_tumor_susceptibility | 1.97764919 |
| 14 | MP0002277_abnormal_respiratory_mucosa | 1.96073482 |
| 15 | MP0002736_abnormal_nociception_after | 1.84991833 |
| 16 | MP0005646_abnormal_pituitary_gland | 1.78306935 |
| 17 | MP0001188_hyperpigmentation | 1.75735150 |
| 18 | MP0001968_abnormal_touch/_nociception | 1.73878404 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 1.72876396 |
| 20 | MP0003878_abnormal_ear_physiology | 1.69978395 |
| 21 | MP0005377_hearing/vestibular/ear_phenot | 1.69978395 |
| 22 | MP0002160_abnormal_reproductive_system | 1.68726454 |
| 23 | MP0005389_reproductive_system_phenotype | 1.68656021 |
| 24 | MP0009785_altered_susceptibility_to | 1.68479595 |
| 25 | MP0001919_abnormal_reproductive_system | 1.66009937 |
| 26 | MP0003693_abnormal_embryo_hatching | 1.63508776 |
| 27 | MP0003646_muscle_fatigue | 1.60659418 |
| 28 | MP0008875_abnormal_xenobiotic_pharmacok | 1.55845860 |
| 29 | MP0009046_muscle_twitch | 1.52181557 |
| 30 | MP0003195_calcinosis | 1.51076666 |
| 31 | MP0004142_abnormal_muscle_tone | 1.41922088 |
| 32 | MP0002006_tumorigenesis | 1.41590278 |
| 33 | MP0008877_abnormal_DNA_methylation | 1.36197311 |
| 34 | MP0001905_abnormal_dopamine_level | 1.33961765 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.33527305 |
| 36 | MP0001542_abnormal_bone_strength | 1.32998464 |
| 37 | MP0008872_abnormal_physiological_respon | 1.31728957 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.29496050 |
| 39 | MP0002102_abnormal_ear_morphology | 1.29452747 |
| 40 | MP0006072_abnormal_retinal_apoptosis | 1.28560728 |
| 41 | MP0009745_abnormal_behavioral_response | 1.27891981 |
| 42 | MP0001853_heart_inflammation | 1.26890646 |
| 43 | MP0006276_abnormal_autonomic_nervous | 1.22015230 |
| 44 | MP0002938_white_spotting | 1.20911737 |
| 45 | MP0005645_abnormal_hypothalamus_physiol | 1.20369406 |
| 46 | MP0006036_abnormal_mitochondrial_physio | 1.19126562 |
| 47 | MP0000049_abnormal_middle_ear | 1.15883787 |
| 48 | MP0003866_abnormal_defecation | 1.15105678 |
| 49 | MP0005636_abnormal_mineral_homeostasis | 1.14563091 |
| 50 | MP0000631_abnormal_neuroendocrine_gland | 1.14525629 |
| 51 | MP0002095_abnormal_skin_pigmentation | 1.12161860 |
| 52 | MP0003763_abnormal_thymus_physiology | 1.11675117 |
| 53 | MP0005423_abnormal_somatic_nervous | 1.10616203 |
| 54 | MP0005084_abnormal_gallbladder_morpholo | 1.10342467 |
| 55 | MP0001661_extended_life_span | 1.08909276 |
| 56 | MP0002638_abnormal_pupillary_reflex | 1.08026789 |
| 57 | MP0005187_abnormal_penis_morphology | 1.07448447 |
| 58 | MP0002148_abnormal_hypersensitivity_rea | 1.07445467 |
| 59 | MP0003186_abnormal_redox_activity | 1.04979098 |
| 60 | MP0000685_abnormal_immune_system | 1.04918726 |
| 61 | MP0003787_abnormal_imprinting | 1.01933120 |
| 62 | MP0008995_early_reproductive_senescence | 0.97908802 |
| 63 | MP0008007_abnormal_cellular_replicative | 0.95409472 |
| 64 | MP0001800_abnormal_humoral_immune | 0.94242708 |
| 65 | MP0002234_abnormal_pharynx_morphology | 0.93266499 |
| 66 | MP0005410_abnormal_fertilization | 0.91821300 |
| 67 | MP0002876_abnormal_thyroid_physiology | 0.90766973 |
| 68 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.87440711 |
| 69 | MP0006035_abnormal_mitochondrial_morpho | 0.86847045 |
| 70 | MP0008789_abnormal_olfactory_epithelium | 0.86786903 |
| 71 | MP0002272_abnormal_nervous_system | 0.86331841 |
| 72 | MP0001485_abnormal_pinna_reflex | 0.85472294 |
| 73 | MP0001765_abnormal_ion_homeostasis | 0.84609272 |
| 74 | MP0005025_abnormal_response_to | 0.84206139 |
| 75 | MP0002420_abnormal_adaptive_immunity | 0.82722344 |
| 76 | MP0003011_delayed_dark_adaptation | 0.81805382 |
| 77 | MP0000678_abnormal_parathyroid_gland | 0.81519652 |
| 78 | MP0005332_abnormal_amino_acid | 0.81127321 |
| 79 | MP0002751_abnormal_autonomic_nervous | 0.80784821 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.80709278 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.80603677 |
| 82 | MP0002723_abnormal_immune_serum | 0.80421654 |
| 83 | MP0003567_abnormal_fetal_cardiomyocyte | 0.78242482 |
| 84 | MP0000639_abnormal_adrenal_gland | 0.77641327 |
| 85 | MP0002210_abnormal_sex_determination | 0.77591827 |
| 86 | MP0001819_abnormal_immune_cell | 0.76436123 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.75143509 |
| 88 | MP0001881_abnormal_mammary_gland | 0.74207057 |
| 89 | MP0001790_abnormal_immune_system | 0.72363752 |
| 90 | MP0005387_immune_system_phenotype | 0.72363752 |
| 91 | MP0000604_amyloidosis | 0.71424537 |
| 92 | MP0003806_abnormal_nucleotide_metabolis | 0.69823395 |
| 93 | MP0004885_abnormal_endolymph | 0.69327766 |
| 94 | MP0001764_abnormal_homeostasis | 0.69135298 |
| 95 | MP0002933_joint_inflammation | 0.68943916 |
| 96 | MP0002064_seizures | 0.67534252 |
| 97 | MP0009643_abnormal_urine_homeostasis | 0.66499508 |
| 98 | MP0006082_CNS_inflammation | 0.66470757 |
| 99 | MP0003136_yellow_coat_color | 0.66378830 |
| 100 | MP0001119_abnormal_female_reproductive | 0.65960064 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 5.59663252 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 5.34691857 |
| 3 | Renal Fanconi syndrome (HP:0001994) | 5.02515218 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.89119114 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 4.76836568 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 4.69669457 |
| 7 | Increased intramyocellular lipid droplets (HP:0012240) | 4.68742186 |
| 8 | Increased CSF lactate (HP:0002490) | 4.43433620 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.32684413 |
| 10 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.17255035 |
| 11 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.17255035 |
| 12 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.99992348 |
| 13 | Acute encephalopathy (HP:0006846) | 3.96451323 |
| 14 | Increased muscle lipid content (HP:0009058) | 3.88560550 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.84298923 |
| 16 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.79385225 |
| 17 | Aplastic anemia (HP:0001915) | 3.78573705 |
| 18 | Exertional dyspnea (HP:0002875) | 3.53451058 |
| 19 | Hepatic necrosis (HP:0002605) | 3.43425325 |
| 20 | Hepatocellular necrosis (HP:0001404) | 3.36789270 |
| 21 | Lactic acidosis (HP:0003128) | 3.35925812 |
| 22 | Increased serum lactate (HP:0002151) | 3.26807746 |
| 23 | Cerebral edema (HP:0002181) | 3.24916188 |
| 24 | Generalized aminoaciduria (HP:0002909) | 3.23923975 |
| 25 | Abnormality of renal resorption (HP:0011038) | 3.12692377 |
| 26 | Congenital stationary night blindness (HP:0007642) | 3.05523450 |
| 27 | IgG deficiency (HP:0004315) | 3.05264620 |
| 28 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.03865497 |
| 29 | Respiratory difficulties (HP:0002880) | 3.03361781 |
| 30 | Hyperphosphaturia (HP:0003109) | 3.00052667 |
| 31 | Abnormality of urine glucose concentration (HP:0011016) | 2.89212322 |
| 32 | Glycosuria (HP:0003076) | 2.89212322 |
| 33 | Macrocytic anemia (HP:0001972) | 2.80341036 |
| 34 | Exercise intolerance (HP:0003546) | 2.78697615 |
| 35 | Abnormal number of erythroid precursors (HP:0012131) | 2.73722632 |
| 36 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.73239516 |
| 37 | Stomatitis (HP:0010280) | 2.56062447 |
| 38 | Optic disc pallor (HP:0000543) | 2.54796974 |
| 39 | Respiratory failure (HP:0002878) | 2.54272538 |
| 40 | Reticulocytopenia (HP:0001896) | 2.49767423 |
| 41 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.46236271 |
| 42 | Abnormality of alanine metabolism (HP:0010916) | 2.46236271 |
| 43 | Hyperalaninemia (HP:0003348) | 2.46236271 |
| 44 | Severe combined immunodeficiency (HP:0004430) | 2.45391073 |
| 45 | Progressive microcephaly (HP:0000253) | 2.42852694 |
| 46 | Pancytopenia (HP:0001876) | 2.38277152 |
| 47 | Oral leukoplakia (HP:0002745) | 2.35241960 |
| 48 | Type II lissencephaly (HP:0007260) | 2.35210852 |
| 49 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.31905517 |
| 50 | Metaphyseal dysplasia (HP:0100255) | 2.30040028 |
| 51 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.28975555 |
| 52 | Abnormal urine phosphate concentration (HP:0012599) | 2.27106349 |
| 53 | T lymphocytopenia (HP:0005403) | 2.26059596 |
| 54 | Congenital, generalized hypertrichosis (HP:0004540) | 2.25425015 |
| 55 | Increased IgM level (HP:0003496) | 2.22004176 |
| 56 | Lethargy (HP:0001254) | 2.19479257 |
| 57 | Cerebral hypomyelination (HP:0006808) | 2.15659368 |
| 58 | Abnormality of T cell number (HP:0011839) | 2.12804253 |
| 59 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.11997173 |
| 60 | Renal cortical cysts (HP:0000803) | 2.11215419 |
| 61 | Pancreatic cysts (HP:0001737) | 2.11129995 |
| 62 | Abnormality of midbrain morphology (HP:0002418) | 2.07033655 |
| 63 | Molar tooth sign on MRI (HP:0002419) | 2.07033655 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.00790317 |
| 65 | Abnormality of T cells (HP:0002843) | 1.98469279 |
| 66 | Pancreatic fibrosis (HP:0100732) | 1.94467750 |
| 67 | Leukodystrophy (HP:0002415) | 1.93144286 |
| 68 | Abnormality of magnesium homeostasis (HP:0004921) | 1.92697951 |
| 69 | Abnormality of placental membranes (HP:0011409) | 1.92445512 |
| 70 | Amniotic constriction ring (HP:0009775) | 1.92445512 |
| 71 | Cellular immunodeficiency (HP:0005374) | 1.92411924 |
| 72 | Testicular atrophy (HP:0000029) | 1.90565083 |
| 73 | True hermaphroditism (HP:0010459) | 1.85112247 |
| 74 | Dicarboxylic aciduria (HP:0003215) | 1.84569888 |
| 75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.84569888 |
| 76 | Abnormality of the renal cortex (HP:0011035) | 1.84546536 |
| 77 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.84423084 |
| 78 | Absent/shortened dynein arms (HP:0200106) | 1.84423084 |
| 79 | Renal tubular dysfunction (HP:0000124) | 1.83081677 |
| 80 | Myokymia (HP:0002411) | 1.82949148 |
| 81 | Pallor (HP:0000980) | 1.80625533 |
| 82 | Constricted visual fields (HP:0001133) | 1.79926946 |
| 83 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.79085975 |
| 84 | Concave nail (HP:0001598) | 1.72342621 |
| 85 | Hypoproteinemia (HP:0003075) | 1.70975216 |
| 86 | Muscle fiber atrophy (HP:0100295) | 1.68787413 |
| 87 | Type 2 muscle fiber atrophy (HP:0003554) | 1.65975256 |
| 88 | Rib fusion (HP:0000902) | 1.65955934 |
| 89 | Combined immunodeficiency (HP:0005387) | 1.65439250 |
| 90 | Opisthotonus (HP:0002179) | 1.64857528 |
| 91 | Retinal dysplasia (HP:0007973) | 1.64036203 |
| 92 | Tetany (HP:0001281) | 1.62696400 |
| 93 | Nausea (HP:0002018) | 1.62694717 |
| 94 | Sparse eyelashes (HP:0000653) | 1.60988489 |
| 95 | Neuroendocrine neoplasm (HP:0100634) | 1.58653778 |
| 96 | Emotional lability (HP:0000712) | 1.58466187 |
| 97 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.55203635 |
| 98 | CNS demyelination (HP:0007305) | 1.54610985 |
| 99 | Thyroiditis (HP:0100646) | 1.53539291 |
| 100 | Absent thumb (HP:0009777) | 1.53171953 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 3.73070229 |
| 2 | KDR | 3.68747282 |
| 3 | MAP4K2 | 3.44624549 |
| 4 | BCKDK | 3.11097941 |
| 5 | NUAK1 | 3.01210507 |
| 6 | TXK | 2.93553325 |
| 7 | NME2 | 2.92956970 |
| 8 | VRK2 | 2.57160415 |
| 9 | WNK4 | 2.40981259 |
| 10 | STK16 | 2.29720842 |
| 11 | ZAK | 2.26537061 |
| 12 | MAP3K12 | 2.02984449 |
| 13 | LIMK1 | 2.00279392 |
| 14 | TLK1 | 2.00103504 |
| 15 | BUB1 | 1.97387028 |
| 16 | TESK1 | 1.86678522 |
| 17 | NME1 | 1.85542586 |
| 18 | PDK2 | 1.78798591 |
| 19 | GRK1 | 1.76317787 |
| 20 | MAP3K11 | 1.64020932 |
| 21 | ADRBK2 | 1.60396182 |
| 22 | MAP4K1 | 1.53456866 |
| 23 | EIF2AK1 | 1.45252085 |
| 24 | DYRK2 | 1.41960774 |
| 25 | ITK | 1.39449784 |
| 26 | PIK3CA | 1.37639204 |
| 27 | TIE1 | 1.36484327 |
| 28 | VRK1 | 1.25602633 |
| 29 | DAPK2 | 1.13915240 |
| 30 | NEK1 | 1.13694157 |
| 31 | BMPR1B | 1.10085289 |
| 32 | PLK4 | 1.09995543 |
| 33 | DAPK1 | 1.07878161 |
| 34 | PIM2 | 1.06468787 |
| 35 | STK39 | 1.06282792 |
| 36 | CSNK1G3 | 1.05725411 |
| 37 | MATK | 0.99715932 |
| 38 | NTRK3 | 0.98465924 |
| 39 | FES | 0.94695855 |
| 40 | TEC | 0.94416848 |
| 41 | RPS6KA5 | 0.93028332 |
| 42 | TRIM28 | 0.92267954 |
| 43 | MAPKAPK3 | 0.91712731 |
| 44 | PRKCQ | 0.86319350 |
| 45 | AURKA | 0.86087982 |
| 46 | TAOK3 | 0.85160029 |
| 47 | INSRR | 0.84324416 |
| 48 | MYLK | 0.78666129 |
| 49 | SYK | 0.74475218 |
| 50 | CSNK1A1L | 0.72811702 |
| 51 | CDC7 | 0.72386241 |
| 52 | PINK1 | 0.69757668 |
| 53 | CSNK1G1 | 0.69345040 |
| 54 | CSNK2A2 | 0.69236580 |
| 55 | CSNK1G2 | 0.68184358 |
| 56 | ILK | 0.67191118 |
| 57 | DAPK3 | 0.66416210 |
| 58 | CSNK2A1 | 0.65234954 |
| 59 | CAMKK2 | 0.62864501 |
| 60 | CSK | 0.62697142 |
| 61 | MAPK11 | 0.62140559 |
| 62 | GRK6 | 0.59829099 |
| 63 | AURKB | 0.58774145 |
| 64 | WNK3 | 0.58162740 |
| 65 | LCK | 0.57546347 |
| 66 | ADRBK1 | 0.56362225 |
| 67 | LRRK2 | 0.53740776 |
| 68 | FRK | 0.53695657 |
| 69 | PIM1 | 0.53099371 |
| 70 | PHKG2 | 0.52860452 |
| 71 | PHKG1 | 0.52860452 |
| 72 | NTRK1 | 0.52339204 |
| 73 | PASK | 0.52157832 |
| 74 | GRK7 | 0.51727128 |
| 75 | EIF2AK3 | 0.51443084 |
| 76 | GRK5 | 0.50789212 |
| 77 | KIT | 0.50530917 |
| 78 | LYN | 0.49778855 |
| 79 | ABL2 | 0.48379889 |
| 80 | ATR | 0.45832863 |
| 81 | MUSK | 0.45367050 |
| 82 | RIPK4 | 0.45297657 |
| 83 | ZAP70 | 0.44341007 |
| 84 | OBSCN | 0.43586304 |
| 85 | OXSR1 | 0.42979091 |
| 86 | PRKCG | 0.42781335 |
| 87 | AKT2 | 0.42486873 |
| 88 | MAPK13 | 0.41829651 |
| 89 | PRKACA | 0.41031274 |
| 90 | CSNK1A1 | 0.41017863 |
| 91 | IKBKB | 0.40706191 |
| 92 | ERBB2 | 0.40205572 |
| 93 | PRKCA | 0.39410006 |
| 94 | MAPKAPK5 | 0.38693839 |
| 95 | RPS6KA4 | 0.38195524 |
| 96 | INSR | 0.38103226 |
| 97 | CDK8 | 0.37592272 |
| 98 | SRPK1 | 0.36946735 |
| 99 | BCR | 0.35717906 |
| 100 | PLK2 | 0.32983602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.00900742 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.88011448 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.71329623 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 4.33538613 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.93221445 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.88965420 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.54957451 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.50482285 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.46969480 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.42366408 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.34426926 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25121851 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.06603271 |
| 14 | DNA replication_Homo sapiens_hsa03030 | 1.77009164 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.63554723 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.62797673 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.52361020 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.49676163 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.41126101 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.40131175 |
| 21 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39305596 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.38212775 |
| 23 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.30146463 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.29458488 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.29377875 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.19724094 |
| 27 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.17096529 |
| 28 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17030530 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.16700935 |
| 30 | Mismatch repair_Homo sapiens_hsa03430 | 1.14640346 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.08116497 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.03825208 |
| 33 | Sulfur relay system_Homo sapiens_hsa04122 | 1.03075863 |
| 34 | Asthma_Homo sapiens_hsa05310 | 1.02696817 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.01538700 |
| 36 | RNA transport_Homo sapiens_hsa03013 | 1.00889992 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.98895860 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.98341182 |
| 39 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.96051472 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.95440256 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94449945 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.93367419 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.93254219 |
| 44 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.90176569 |
| 45 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.88842635 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.83767428 |
| 47 | RNA degradation_Homo sapiens_hsa03018 | 0.82199343 |
| 48 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.77890356 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76530768 |
| 50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76170310 |
| 51 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75063494 |
| 52 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.74191784 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.73877796 |
| 54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.73302880 |
| 55 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.72906212 |
| 56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71935397 |
| 57 | Base excision repair_Homo sapiens_hsa03410 | 0.68607989 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.68487078 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65915864 |
| 60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.54316965 |
| 61 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.54075913 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53650688 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.53085586 |
| 64 | Peroxisome_Homo sapiens_hsa04146 | 0.50612507 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50459286 |
| 66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.50063163 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.48073718 |
| 68 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47016366 |
| 69 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46586807 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.45952475 |
| 71 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43395139 |
| 72 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.41356595 |
| 73 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38665105 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.38360452 |
| 75 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.37582121 |
| 76 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37532339 |
| 77 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.34573273 |
| 78 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.34429290 |
| 79 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.33987007 |
| 80 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32834980 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.28856083 |
| 82 | Olfactory transduction_Homo sapiens_hsa04740 | 0.27650534 |
| 83 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27485074 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.24708225 |
| 85 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.24046910 |
| 86 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.22924681 |
| 87 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.22887157 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.22855789 |
| 89 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.19883366 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.18990073 |
| 91 | Morphine addiction_Homo sapiens_hsa05032 | 0.18843722 |
| 92 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.18465787 |
| 93 | Nicotine addiction_Homo sapiens_hsa05033 | 0.18407464 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.17760700 |
| 95 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.17095456 |
| 96 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.16988970 |
| 97 | Measles_Homo sapiens_hsa05162 | 0.16507270 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.16373211 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.15938540 |
| 100 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.15261414 |

