CHCHD7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.26646366
2ATP synthesis coupled proton transport (GO:0015986)5.90475254
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.90475254
4ribosomal small subunit assembly (GO:0000028)5.82944299
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.80713386
6respiratory electron transport chain (GO:0022904)5.71061718
7electron transport chain (GO:0022900)5.57060334
8DNA deamination (GO:0045006)5.54252036
9oxidative phosphorylation (GO:0006119)5.49694458
10protein complex biogenesis (GO:0070271)5.46800310
11deoxyribonucleoside monophosphate metabolic process (GO:0009162)5.39147637
12mitochondrial respiratory chain complex I assembly (GO:0032981)5.31109676
13NADH dehydrogenase complex assembly (GO:0010257)5.31109676
14mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.31109676
15mitochondrial respiratory chain complex assembly (GO:0033108)5.10267854
16establishment of protein localization to mitochondrial membrane (GO:0090151)4.91459811
17chaperone-mediated protein transport (GO:0072321)4.87416508
18polyketide metabolic process (GO:0030638)4.86663721
19doxorubicin metabolic process (GO:0044598)4.86663721
20daunorubicin metabolic process (GO:0044597)4.86663721
21respiratory chain complex IV assembly (GO:0008535)4.80436805
22ubiquinone biosynthetic process (GO:0006744)4.54113365
23quinone biosynthetic process (GO:1901663)4.54113365
24SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.45506026
25signal peptide processing (GO:0006465)4.45470362
26regulation of mitochondrial translation (GO:0070129)4.41587271
27cotranslational protein targeting to membrane (GO:0006613)4.37437891
28protein neddylation (GO:0045116)4.35729138
29protein targeting to ER (GO:0045047)4.33818134
30cytochrome complex assembly (GO:0017004)4.26782140
31viral transcription (GO:0019083)4.24554750
32protein localization to endoplasmic reticulum (GO:0070972)4.22466638
33translational termination (GO:0006415)4.17309172
34establishment of protein localization to endoplasmic reticulum (GO:0072599)4.11964209
35aerobic respiration (GO:0009060)4.10442333
36maturation of SSU-rRNA (GO:0030490)4.05807238
37tRNA methylation (GO:0030488)4.00773313
38ubiquinone metabolic process (GO:0006743)3.97018785
39negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.96569752
40ribosomal small subunit biogenesis (GO:0042274)3.86252956
41iron-sulfur cluster assembly (GO:0016226)3.83522229
42metallo-sulfur cluster assembly (GO:0031163)3.83522229
43translational elongation (GO:0006414)3.77046556
44proteasome assembly (GO:0043248)3.73149321
45positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.69917525
46termination of RNA polymerase III transcription (GO:0006386)3.65417480
47transcription elongation from RNA polymerase III promoter (GO:0006385)3.65417480
48regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.65251630
49translation (GO:0006412)3.64282011
50GDP-mannose metabolic process (GO:0019673)3.61976240
51GTP biosynthetic process (GO:0006183)3.60369188
52negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.57476833
53negative regulation of ligase activity (GO:0051352)3.57476833
54inner mitochondrial membrane organization (GO:0007007)3.55407473
55guanosine-containing compound biosynthetic process (GO:1901070)3.55300705
56anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.45806842
57purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.45303090
58purine nucleoside triphosphate biosynthetic process (GO:0009145)3.42115498
59ATP biosynthetic process (GO:0006754)3.40998491
60L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.39724989
61ribosomal large subunit biogenesis (GO:0042273)3.37441785
62regulation of cellular amino acid metabolic process (GO:0006521)3.37201176
63DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.36243463
64signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.32018865
65signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.32018865
66signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.32018865
67cullin deneddylation (GO:0010388)3.29421284
68histone mRNA metabolic process (GO:0008334)3.28677686
69spliceosomal snRNP assembly (GO:0000387)3.28527432
70viral life cycle (GO:0019058)3.27936742
71intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.27117333
72signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.27117333
73aminoglycoside antibiotic metabolic process (GO:0030647)3.25773436
74ribonucleoside triphosphate biosynthetic process (GO:0009201)3.21026946
75intracellular protein transmembrane import (GO:0044743)3.20611395
76CTP metabolic process (GO:0046036)3.18239098
77CTP biosynthetic process (GO:0006241)3.18239098
78rRNA processing (GO:0006364)3.17454473
79nuclear-transcribed mRNA catabolic process (GO:0000956)3.17417686
80signal transduction involved in DNA damage checkpoint (GO:0072422)3.17286864
81signal transduction involved in DNA integrity checkpoint (GO:0072401)3.17286864
82heart process (GO:0003015)3.17077957
83heart contraction (GO:0060047)3.17077957
84cellular protein complex disassembly (GO:0043624)3.16926507
85protein localization to mitochondrion (GO:0070585)3.16129951
86protein deneddylation (GO:0000338)3.15920329
87protein complex disassembly (GO:0043241)3.15759877
88proton transport (GO:0015992)3.15722102
89positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.15352941
90signal transduction involved in cell cycle checkpoint (GO:0072395)3.13648909
91peptidyl-histidine modification (GO:0018202)3.11465064
92hydrogen transport (GO:0006818)3.09765062
93tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.09032050
94RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.09032050
95cellular component biogenesis (GO:0044085)3.08914954
96DNA replication checkpoint (GO:0000076)3.07563472
97rRNA metabolic process (GO:0016072)3.07307918
98macromolecular complex disassembly (GO:0032984)3.07307516
99platelet dense granule organization (GO:0060155)3.07177627
100quinone metabolic process (GO:1901661)3.07148107
101GMP metabolic process (GO:0046037)3.05898975
102CENP-A containing nucleosome assembly (GO:0034080)3.04793002
103cellular respiration (GO:0045333)3.04207913
104deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.03945802
105positive regulation of ligase activity (GO:0051351)3.03386952
106chromatin remodeling at centromere (GO:0031055)3.01040505
107regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.00937423
108regulation of mitotic spindle checkpoint (GO:1903504)3.00937423
109protein targeting to mitochondrion (GO:0006626)3.00218598
110pseudouridine synthesis (GO:0001522)2.99541900
111rRNA modification (GO:0000154)2.99076442
112mRNA catabolic process (GO:0006402)2.98855637
113hydrogen ion transmembrane transport (GO:1902600)2.98338797
114ribonucleoprotein complex biogenesis (GO:0022613)2.97984920
115exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.97630441
116UTP biosynthetic process (GO:0006228)2.96794964
117translational initiation (GO:0006413)2.96788715
118nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.95962848
1197-methylguanosine mRNA capping (GO:0006370)2.94666760
120pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.92881312
121pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.92757537
122water-soluble vitamin biosynthetic process (GO:0042364)2.91554049
123spliceosomal complex assembly (GO:0000245)2.91065371
124mitochondrial transport (GO:0006839)2.89411715
125nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87460893
1267-methylguanosine RNA capping (GO:0009452)2.87208853
127telomere maintenance via semi-conservative replication (GO:0032201)2.85065163
128deoxyribose phosphate biosynthetic process (GO:0046385)2.84112283
1292-deoxyribonucleotide biosynthetic process (GO:0009265)2.84112283
130RNA methylation (GO:0001510)2.84010777
131protein targeting to membrane (GO:0006612)2.77930426
132pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.77195607
133nucleoside triphosphate biosynthetic process (GO:0009142)2.76995402
134nucleobase-containing small molecule interconversion (GO:0015949)2.76528054
135pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.74426674
136rRNA methylation (GO:0031167)2.73492015
137purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.73382018
138establishment of protein localization to mitochondrion (GO:0072655)2.73359488
139purine-containing compound salvage (GO:0043101)2.73019187
140tricarboxylic acid cycle (GO:0006099)2.71753752
141ribonucleoprotein complex disassembly (GO:0032988)2.71142912
142UTP metabolic process (GO:0046051)2.70450487
143deoxyribonucleotide metabolic process (GO:0009262)2.68153188
144pyrimidine nucleoside biosynthetic process (GO:0046134)2.67866795
145mitochondrial DNA replication (GO:0006264)2.67466774
146regulation of oxidative phosphorylation (GO:0002082)2.66957021

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.54115706
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.15000630
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.10487785
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.94142625
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.86512986
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.60532807
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.55572987
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.26208899
9SRF_21415370_ChIP-Seq_HL-1_Mouse3.19486645
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.18486799
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.12932578
12ELF1_17652178_ChIP-ChIP_JURKAT_Human3.10376244
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.05118433
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.91203525
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.84235475
16PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.83079798
17VDR_23849224_ChIP-Seq_CD4+_Human2.66628552
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.65616651
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.51999514
20FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.46899125
21* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.42304154
22FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.41076945
23THAP11_20581084_ChIP-Seq_MESCs_Mouse2.40089588
24MYC_19030024_ChIP-ChIP_MESCs_Mouse2.34520305
25DCP1A_22483619_ChIP-Seq_HELA_Human2.33757274
26FOXP3_21729870_ChIP-Seq_TREG_Human2.32130308
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.31751810
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.31311183
29* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.30105158
30HOXB4_20404135_ChIP-ChIP_EML_Mouse2.16657576
31* ERG_20887958_ChIP-Seq_HPC-7_Mouse2.16002238
32XRN2_22483619_ChIP-Seq_HELA_Human2.11483267
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.09351957
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.08749737
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.98591976
36GABP_19822575_ChIP-Seq_HepG2_Human1.96747009
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.94454190
38ELK1_19687146_ChIP-ChIP_HELA_Human1.88604334
39TTF2_22483619_ChIP-Seq_HELA_Human1.83047611
40NELFA_20434984_ChIP-Seq_ESCs_Mouse1.76978104
41* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.70852628
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.70748598
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65520163
44MYC_19079543_ChIP-ChIP_MESCs_Mouse1.61199611
45NOTCH1_21737748_ChIP-Seq_TLL_Human1.61031692
46BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.60643785
47EWS_26573619_Chip-Seq_HEK293_Human1.58628778
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.56397509
49CIITA_25753668_ChIP-Seq_RAJI_Human1.53829211
50LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52875734
51IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.52083144
52ZNF274_21170338_ChIP-Seq_K562_Hela1.49507545
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49278835
54GATA1_22025678_ChIP-Seq_K562_Human1.45128419
55GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.43751393
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.43221340
57IRF8_22096565_ChIP-ChIP_GC-B_Human1.38744621
58* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.37606154
59FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.37406591
60CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.36646105
61FUS_26573619_Chip-Seq_HEK293_Human1.34936124
62CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.34431647
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.32616548
64RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.31559948
65HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.22352078
66ELK1_22589737_ChIP-Seq_MCF10A_Human1.22280664
67SCL_19346495_ChIP-Seq_HPC-7_Human1.22278364
68MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.20743577
69E2F7_22180533_ChIP-Seq_HELA_Human1.20700354
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18546982
71* MYC_18940864_ChIP-ChIP_HL60_Human1.16266552
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15693641
73SPI1_23547873_ChIP-Seq_NB4_Human1.15181372
74PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.15068060
75VDR_22108803_ChIP-Seq_LS180_Human1.15025952
76TP53_22573176_ChIP-Seq_HFKS_Human1.13830117
77MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.12416480
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11526172
79CTCF_18555785_ChIP-Seq_MESCs_Mouse1.10437319
80DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10400599
81LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07883510
82E2F4_17652178_ChIP-ChIP_JURKAT_Human1.07711242
83IGF1R_20145208_ChIP-Seq_DFB_Human1.05718583
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.04788942
85CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.03692951
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.03680176
87TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03542625
88IRF1_19129219_ChIP-ChIP_H3396_Human1.03381092
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03278058
90POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00445646
91EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00328680
92SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00269471
93GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98718948
94TBX5_21415370_ChIP-Seq_HL-1_Mouse0.98605178
95POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.98307377
96BP1_19119308_ChIP-ChIP_Hs578T_Human0.96813967
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95550954
98KDM5A_27292631_Chip-Seq_BREAST_Human0.93970682
99GATA4_21415370_ChIP-Seq_HL-1_Mouse0.93623153
100CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92889337
101MYCN_18555785_ChIP-Seq_MESCs_Mouse0.92599797
102TFEB_21752829_ChIP-Seq_HELA_Human0.91710944
103EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.90696354
104E2F1_21310950_ChIP-Seq_MCF-7_Human0.90493847
105GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90369190
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89776584
107FOXA1_25329375_ChIP-Seq_VCAP_Human0.88449663
108FOXA1_27270436_Chip-Seq_PROSTATE_Human0.88449663
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85101278
110NANOG_18555785_ChIP-Seq_MESCs_Mouse0.84480054
111GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84007653
112MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.83551382
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82304802
114P300_19829295_ChIP-Seq_ESCs_Human0.82279721
115ERG_20517297_ChIP-Seq_VCAP_Human0.81516884
116* SALL4_22934838_ChIP-ChIP_CD34+_Human0.81501808
117SOX2_19829295_ChIP-Seq_ESCs_Human0.80838424
118NANOG_19829295_ChIP-Seq_ESCs_Human0.80838424
119GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80253546
120HTT_18923047_ChIP-ChIP_STHdh_Human0.79411282
121TAF15_26573619_Chip-Seq_HEK293_Human0.78867718
122E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.78303716
123AR_20517297_ChIP-Seq_VCAP_Human0.78207351
124RBPJ_22232070_ChIP-Seq_NCS_Mouse0.77873614
125ELF5_23300383_ChIP-Seq_T47D_Human0.77665446
126NANOG_16153702_ChIP-ChIP_HESCs_Human0.76995256
127NFE2_27457419_Chip-Seq_LIVER_Mouse0.76829445
128EZH2_27294783_Chip-Seq_NPCs_Mouse0.75479084
129STAT1_20625510_ChIP-Seq_HELA_Human0.73976237
130SUZ12_27294783_Chip-Seq_NPCs_Mouse0.72244090

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006036_abnormal_mitochondrial_physio3.58342941
2MP0006292_abnormal_olfactory_placode3.52699074
3MP0004147_increased_porphyrin_level3.16941372
4MP0009379_abnormal_foot_pigmentation3.16939520
5MP0001986_abnormal_taste_sensitivity2.94494007
6MP0000749_muscle_degeneration2.79052787
7MP0003646_muscle_fatigue2.76186397
8MP0004043_abnormal_pH_regulation2.74695635
9MP0009697_abnormal_copulation2.70247837
10MP0003718_maternal_effect2.61536282
11MP0002837_dystrophic_cardiac_calcinosis2.45122734
12MP0002638_abnormal_pupillary_reflex2.29714629
13MP0001188_hyperpigmentation2.19224817
14MP0003186_abnormal_redox_activity2.18623652
15MP0005084_abnormal_gallbladder_morpholo2.17598015
16MP0006035_abnormal_mitochondrial_morpho2.15579998
17MP0002132_abnormal_respiratory_system2.14950123
18MP0002102_abnormal_ear_morphology2.08261647
19MP0004215_abnormal_myocardial_fiber2.05255499
20MP0005174_abnormal_tail_pigmentation2.00525305
21MP0005075_abnormal_melanosome_morpholog1.99580380
22MP0003693_abnormal_embryo_hatching1.91244540
23MP0004084_abnormal_cardiac_muscle1.80951611
24MP0003077_abnormal_cell_cycle1.79583654
25MP0005330_cardiomyopathy1.78358393
26MP0008995_early_reproductive_senescence1.77661457
27MP0001764_abnormal_homeostasis1.66636267
28MP0002938_white_spotting1.63180821
29MP0005379_endocrine/exocrine_gland_phen1.59693507
30MP0004036_abnormal_muscle_relaxation1.54802418
31MP0010386_abnormal_urinary_bladder1.52702094
32MP0002163_abnormal_gland_morphology1.51093187
33MP0003123_paternal_imprinting1.49471046
34MP0002095_abnormal_skin_pigmentation1.49451230
35MP0003111_abnormal_nucleus_morphology1.49261029
36MP0000678_abnormal_parathyroid_gland1.48699521
37MP0008789_abnormal_olfactory_epithelium1.47606933
38MP0004145_abnormal_muscle_electrophysio1.47414445
39MP0008007_abnormal_cellular_replicative1.46107886
40MP0008058_abnormal_DNA_repair1.43268721
41MP0003806_abnormal_nucleotide_metabolis1.40216377
42MP0003724_increased_susceptibility_to1.36049778
43MP0002877_abnormal_melanocyte_morpholog1.33541858
44MP0006054_spinal_hemorrhage1.32556219
45MP0005220_abnormal_exocrine_pancreas1.32453620
46MP0008932_abnormal_embryonic_tissue1.31038889
47MP0006072_abnormal_retinal_apoptosis1.30752608
48MP0002693_abnormal_pancreas_physiology1.29905406
49MP0005645_abnormal_hypothalamus_physiol1.29621456
50MP0002234_abnormal_pharynx_morphology1.28910551
51MP0001984_abnormal_olfaction1.28213228
52MP0004957_abnormal_blastocyst_morpholog1.26383826
53MP0000372_irregular_coat_pigmentation1.26113636
54MP0003137_abnormal_impulse_conducting1.22472879
55MP0005671_abnormal_response_to1.22404168
56MP0004484_altered_response_of1.21990028
57MP0000015_abnormal_ear_pigmentation1.20369221
58MP0002277_abnormal_respiratory_mucosa1.19259606
59MP0003195_calcinosis1.17399575
60MP0002972_abnormal_cardiac_muscle1.16675239
61MP0002396_abnormal_hematopoietic_system1.16535017
62MP0004142_abnormal_muscle_tone1.16329508
63MP0005636_abnormal_mineral_homeostasis1.10060586
64MP0008872_abnormal_physiological_respon1.09503299
65MP0001835_abnormal_antigen_presentation1.08314705
66MP0003252_abnormal_bile_duct1.07901725
67MP0001800_abnormal_humoral_immune1.07656355
68MP0001905_abnormal_dopamine_level1.07635072
69MP0002138_abnormal_hepatobiliary_system1.07532603
70MP0001664_abnormal_digestion1.07113555
71MP0002160_abnormal_reproductive_system1.07105209
72MP0005646_abnormal_pituitary_gland1.06317178
73MP0009046_muscle_twitch1.06194870
74MP0001529_abnormal_vocalization1.05089213
75MP0009785_altered_susceptibility_to1.04823954
76MP0001929_abnormal_gametogenesis1.04145363
77MP0005551_abnormal_eye_electrophysiolog1.03744654
78MP0004510_myositis1.02408197
79MP0008877_abnormal_DNA_methylation1.01845653
80MP0000358_abnormal_cell_content/1.00948298
81MP0002139_abnormal_hepatobiliary_system1.00786344
82MP0001666_abnormal_nutrient_absorption0.99936919
83MP0002210_abnormal_sex_determination0.99193834
84MP0004808_abnormal_hematopoietic_stem0.99150631
85MP0000631_abnormal_neuroendocrine_gland0.98205219
86MP0003786_premature_aging0.97989573
87MP0003763_abnormal_thymus_physiology0.96229321
88MP0002106_abnormal_muscle_physiology0.96149793
89MP0003656_abnormal_erythrocyte_physiolo0.95820788
90MP0008775_abnormal_heart_ventricle0.93762074
91MP0005387_immune_system_phenotype0.93286537
92MP0001790_abnormal_immune_system0.93286537
93MP0008875_abnormal_xenobiotic_pharmacok0.93063806
94MP0005394_taste/olfaction_phenotype0.93019336
95MP0005499_abnormal_olfactory_system0.93019336
96MP0003787_abnormal_imprinting0.92649109
97MP0005389_reproductive_system_phenotype0.92546851
98MP0009333_abnormal_splenocyte_physiolog0.91912722
99MP0001853_heart_inflammation0.91771150
100MP0005410_abnormal_fertilization0.91540907
101MP0001544_abnormal_cardiovascular_syste0.90572610
102MP0005385_cardiovascular_system_phenoty0.90572610
103MP0001944_abnormal_pancreas_morphology0.90525643
104MP0005266_abnormal_metabolism0.90051923
105MP0010094_abnormal_chromosome_stability0.90026184
106MP0003121_genomic_imprinting0.88174139
107MP0000569_abnormal_digit_pigmentation0.87843000
108MP0002723_abnormal_immune_serum0.87816480
109MP0003828_pulmonary_edema0.87812473
110MP0005408_hypopigmentation0.86404650
111MP0003880_abnormal_central_pattern0.86245693
112MP0000516_abnormal_urinary_system0.85912456
113MP0005367_renal/urinary_system_phenotyp0.85912456
114MP0000490_abnormal_crypts_of0.85188183
115MP0001145_abnormal_male_reproductive0.84673614
116MP0000653_abnormal_sex_gland0.83900977
117MP0002090_abnormal_vision0.83251342
118MP0009643_abnormal_urine_homeostasis0.83113184
119MP0002452_abnormal_antigen_presenting0.81310131
120MP0003567_abnormal_fetal_cardiomyocyte0.81307523
121MP0008004_abnormal_stomach_pH0.80563718
122MP0004233_abnormal_muscle_weight0.79688396
123MP0002019_abnormal_tumor_incidence0.78994695
124MP0000751_myopathy0.78222764
125MP0000689_abnormal_spleen_morphology0.77828469
126MP0001485_abnormal_pinna_reflex0.77249273
127MP0005165_increased_susceptibility_to0.76725112
128MP0002420_abnormal_adaptive_immunity0.75591664
129MP0001819_abnormal_immune_cell0.75437458
130MP0008873_increased_physiological_sensi0.75386577
131MP0000613_abnormal_salivary_gland0.74607947
132MP0003698_abnormal_male_reproductive0.73125872
133MP0005535_abnormal_body_temperature0.72941458
134MP0001968_abnormal_touch/_nociception0.72366078
135MP0002148_abnormal_hypersensitivity_rea0.71810710
136MP0005253_abnormal_eye_physiology0.71708152
137MP0002332_abnormal_exercise_endurance0.71321783
138MP0003183_abnormal_peptide_metabolism0.71223044
139MP0005395_other_phenotype0.70779447
140MP0005332_abnormal_amino_acid0.69330100
141MP0006276_abnormal_autonomic_nervous0.68900893
142MP0002269_muscular_atrophy0.67582246
143MP0005369_muscle_phenotype0.66156732
144MP0001919_abnormal_reproductive_system0.65516510
145MP0001186_pigmentation_phenotype0.64087109
146MP0000230_abnormal_systemic_arterial0.63167317
147MP0000313_abnormal_cell_death0.62893199
148MP0002078_abnormal_glucose_homeostasis0.62002627

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.54938371
2Mitochondrial inheritance (HP:0001427)5.31542793
3Abnormal activity of mitochondrial respiratory chain (HP:0011922)5.27412973
4Decreased activity of mitochondrial respiratory chain (HP:0008972)5.27412973
5Abnormal mitochondria in muscle tissue (HP:0008316)5.25388396
6Hepatic necrosis (HP:0002605)5.22854410
7Hepatocellular necrosis (HP:0001404)5.19777295
8Increased CSF lactate (HP:0002490)4.70048687
9Acute encephalopathy (HP:0006846)4.65715703
10Progressive macrocephaly (HP:0004481)4.49989514
11Increased hepatocellular lipid droplets (HP:0006565)4.11865740
12Lipid accumulation in hepatocytes (HP:0006561)4.04780609
13Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.04759774
14Renal Fanconi syndrome (HP:0001994)4.02463397
15Lactic acidosis (HP:0003128)3.88692937
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.85621821
17Increased intramyocellular lipid droplets (HP:0012240)3.76978060
18Increased serum lactate (HP:0002151)3.62993767
19Increased muscle lipid content (HP:0009058)3.56326449
20Generalized aminoaciduria (HP:0002909)3.49385201
21Exercise intolerance (HP:0003546)3.48640874
22Abnormality of the heme biosynthetic pathway (HP:0010472)3.39674590
23Cerebral edema (HP:0002181)3.38239182
24Type I transferrin isoform profile (HP:0003642)3.28369922
25Abnormal number of erythroid precursors (HP:0012131)3.15941762
26Aplastic anemia (HP:0001915)3.13161317
27Abnormality of cells of the erythroid lineage (HP:0012130)3.09972598
28Respiratory failure (HP:0002878)3.09634946
29Ragged-red muscle fibers (HP:0003200)3.03392069
303-Methylglutaconic aciduria (HP:0003535)2.98021363
31Exertional dyspnea (HP:0002875)2.96877147
32Microvesicular hepatic steatosis (HP:0001414)2.96721348
33Optic disc pallor (HP:0000543)2.85358099
34Abnormality of alanine metabolism (HP:0010916)2.83522187
35Hyperalaninemia (HP:0003348)2.83522187
36Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.83522187
37Respiratory difficulties (HP:0002880)2.79163988
38Palpitations (HP:0001962)2.79099396
39Reticulocytopenia (HP:0001896)2.78267163
40Glycosuria (HP:0003076)2.68538930
41Abnormality of urine glucose concentration (HP:0011016)2.68538930
42Abnormal protein glycosylation (HP:0012346)2.68190196
43Abnormal glycosylation (HP:0012345)2.68190196
44Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.68190196
45Abnormal protein N-linked glycosylation (HP:0012347)2.68190196
46Abnormality of renal resorption (HP:0011038)2.62946929
47Hypoglycemic coma (HP:0001325)2.62136314
48Absent rod-and cone-mediated responses on ERG (HP:0007688)2.59009154
49Abnormality of dicarboxylic acid metabolism (HP:0010995)2.58898006
50Dicarboxylic aciduria (HP:0003215)2.58898006
51Reduced antithrombin III activity (HP:0001976)2.57935360
52Pancreatic cysts (HP:0001737)2.57527320
53Proximal tubulopathy (HP:0000114)2.44125773
54Congenital, generalized hypertrichosis (HP:0004540)2.43250017
55Abnormality of fatty-acid metabolism (HP:0004359)2.40760408
56Hypothermia (HP:0002045)2.38251859
57Hyperphosphaturia (HP:0003109)2.34674828
58Methylmalonic acidemia (HP:0002912)2.29661410
59Severe visual impairment (HP:0001141)2.29365520
60Pallor (HP:0000980)2.28094813
61Aplasia/Hypoplasia of the sacrum (HP:0008517)2.24766873
62Leukodystrophy (HP:0002415)2.24761863
63Medial flaring of the eyebrow (HP:0010747)2.23509728
64Methylmalonic aciduria (HP:0012120)2.23195820
65Lethargy (HP:0001254)2.19621077
66Pancreatic fibrosis (HP:0100732)2.16983478
67Molar tooth sign on MRI (HP:0002419)2.16084107
68Abnormality of midbrain morphology (HP:0002418)2.16084107
69Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.15483965
70Congenital sensorineural hearing impairment (HP:0008527)2.13085635
71Neuroendocrine neoplasm (HP:0100634)2.11707208
72Myoglobinuria (HP:0002913)2.08996676
73Macrocytic anemia (HP:0001972)2.08858726
74Abnormal rod and cone electroretinograms (HP:0008323)2.07869703
75Increased serum pyruvate (HP:0003542)2.05177895
76Abnormality of glycolysis (HP:0004366)2.05177895
77Abnormality of the pons (HP:0007361)2.04840208
78Pancytopenia (HP:0001876)2.03423640
79Meckel diverticulum (HP:0002245)2.03239937
80Atrial fibrillation (HP:0005110)2.02174773
81Prolonged QT interval (HP:0001657)2.02110524
82Oral leukoplakia (HP:0002745)2.01435206
83Abnormality of the ileum (HP:0001549)1.97806730
84Renal tubular dysfunction (HP:0000124)1.96012856
85Absent thumb (HP:0009777)1.95480728
86CNS demyelination (HP:0007305)1.95148673
87X-linked dominant inheritance (HP:0001423)1.94031180
88Abnormality of aspartate family amino acid metabolism (HP:0010899)1.94019604
89Abnormality of methionine metabolism (HP:0010901)1.93716910
9011 pairs of ribs (HP:0000878)1.93642402
91Supraventricular tachycardia (HP:0004755)1.92416173
92Hypoplasia of the pons (HP:0012110)1.89597091
93Dilated cardiomyopathy (HP:0001644)1.89351654
94Colon cancer (HP:0003003)1.88664325
95Progressive inability to walk (HP:0002505)1.88329635
96True hermaphroditism (HP:0010459)1.87595260
97Emotional lability (HP:0000712)1.87501547
98Abnormality of placental membranes (HP:0011409)1.85739099
99Amniotic constriction ring (HP:0009775)1.85739099
100Abnormality of chromosome stability (HP:0003220)1.85538032
101Congenital primary aphakia (HP:0007707)1.84827328
102Abnormality of vitamin B metabolism (HP:0004340)1.83436084
103Abnormality of the preputium (HP:0100587)1.82506701
104Aplasia/Hypoplasia of the uvula (HP:0010293)1.82311653
105Symptomatic seizures (HP:0011145)1.81778931
106Pheochromocytoma (HP:0002666)1.81382395
107Abnormality of the vitamin B12 metabolism (HP:0004341)1.81079257
108Supraventricular arrhythmia (HP:0005115)1.80445437
109Abnormality of serum amino acid levels (HP:0003112)1.79864345
110Primary atrial arrhythmia (HP:0001692)1.79705106
111Renal cortical cysts (HP:0000803)1.79663128
112Ventricular tachycardia (HP:0004756)1.77936061
113Parakeratosis (HP:0001036)1.77469006
114Nausea (HP:0002018)1.75885276
115Rhabdomyolysis (HP:0003201)1.75331251
116Calf muscle hypertrophy (HP:0008981)1.75268111
117Nephrogenic diabetes insipidus (HP:0009806)1.74538737
118Abnormality of the anterior horn cell (HP:0006802)1.74415277
119Degeneration of anterior horn cells (HP:0002398)1.74415277
120Nephronophthisis (HP:0000090)1.73919512
121Abnormal urine phosphate concentration (HP:0012599)1.73466995
122Abolished electroretinogram (ERG) (HP:0000550)1.73147432
123Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.72004190
124Facial diplegia (HP:0001349)1.70645072
125Megaloblastic anemia (HP:0001889)1.69206250
126Petechiae (HP:0000967)1.69119354
127Abnormality of DNA repair (HP:0003254)1.69093592
128Patchy hypopigmentation of hair (HP:0011365)1.68790840
129Abnormal hemoglobin (HP:0011902)1.68310670
130Muscle hypertrophy of the lower extremities (HP:0008968)1.67835095
131Hyperglycinemia (HP:0002154)1.66664494
132Gait imbalance (HP:0002141)1.66176566
133Abnormal EKG (HP:0003115)1.64870938
134Hypoglycemic seizures (HP:0002173)1.62809916
135Stenosis of the external auditory canal (HP:0000402)1.62685609
136Ketoacidosis (HP:0001993)1.62505407
137Severe combined immunodeficiency (HP:0004430)1.61888292

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.98350381
2BCKDK3.57397308
3NME23.47605449
4VRK23.33950240
5MUSK2.98183183
6MAP4K22.84111094
7MYLK2.34008999
8CDC72.07217359
9ZAK1.96278783
10LMTK21.95798973
11PASK1.94691551
12TEC1.94681207
13BUB11.93380619
14TNIK1.88172967
15TLK11.85850895
16EIF2AK11.84249836
17BRSK21.78680236
18EIF2AK31.77799106
19VRK11.76946638
20IRAK31.68991482
21FLT31.68760025
22WNK31.68220969
23TRIM281.64720256
24NME11.53998125
25STK241.50409162
26PDK21.49255002
27NEK11.41647826
28PLK31.41437947
29PIM21.41345724
30CDK81.37296076
31MAP3K121.34194813
32OBSCN1.33873666
33PRPF4B1.30304062
34WEE11.23705953
35TAOK21.22963508
36PIK3CG1.21346888
37WNK41.20786076
38ACVR1B1.20503351
39BRAF1.17955541
40IRAK41.15657721
41ARAF1.10522316
42PRKG21.09663082
43STK38L1.07758827
44DYRK31.07155561
45CDK191.06588448
46TTK1.05743209
47CAMKK21.05435697
48TAF11.05302280
49TIE11.04856668
50PIK3CA1.04554984
51BTK1.02524975
52OXSR11.01031654
53INSRR1.00753070
54PLK40.98469084
55IKBKE0.98306042
56PLK10.97336049
57MAP3K40.96822717
58ADRBK20.94820749
59MAPK150.94599309
60TAOK30.94232513
61BMPR1B0.93515418
62BMPR20.93306062
63TXK0.90567728
64MAP3K110.89936798
65PINK10.89614491
66SRPK10.88922644
67RPS6KB20.88548976
68GRK70.88459549
69STK390.88002788
70KIT0.84062320
71KDR0.82851293
72IKBKB0.80324065
73MAP3K30.79963151
74MST40.77999881
75CDK70.76004586
76NLK0.74257820
77MKNK10.72207783
78PBK0.71713910
79FRK0.71661912
80BRSK10.70644071
81CCNB10.70454679
82YES10.68544219
83STK40.67953177
84CSNK2A20.67210769
85PDK40.67074032
86PDK30.67074032
87PLK20.66856418
88GRK10.65720077
89LIMK10.64577879
90CLK10.64008789
91DYRK20.63804261
92TGFBR10.63245813
93MAP2K70.62809993
94MAP2K60.61635257
95RPS6KA40.60176230
96MKNK20.59862241
97TESK20.59454554
98MAP2K30.59242885
99NEK90.58989183
100MATK0.55735067
101EIF2AK20.53584136
102RPS6KA50.53192592
103MARK30.53170492
104LYN0.52265853
105ZAP700.52193396
106CAMK2D0.52098055
107CSNK1G30.51929638
108AKT30.51621422
109MAP4K10.50885751
110TBK10.50545296
111SIK30.50240869
112CSNK1G10.50010984
113SYK0.49714315
114HIPK20.48942317
115ATR0.48364168
116TSSK60.48252849
117AURKA0.48070257
118PIM10.46772810
119NUAK10.45634371
120MAPKAPK50.45056510
121CSNK2A10.44740568
122TESK10.44489030
123DAPK10.44282120
124ERBB30.43909933
125CHEK20.43617542
126ATM0.40701784
127RPS6KA60.40262420
128RPS6KL10.39399188
129RPS6KC10.39399188
130TRPM70.39130066
131IRAK10.38367780
132PRKCQ0.37830832
133ABL20.37687056
134ADRBK10.37246389
135AURKB0.36407681
136DAPK30.33259037
137BCR0.32803750
138CSNK1A10.31262772
139PRKCE0.30398174

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.61757750
2Ribosome_Homo sapiens_hsa030104.30963247
3Parkinsons disease_Homo sapiens_hsa050124.22168642
4Protein export_Homo sapiens_hsa030603.95372536
5Huntingtons disease_Homo sapiens_hsa050163.03080755
6Alzheimers disease_Homo sapiens_hsa050102.99432298
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.69809108
8RNA polymerase_Homo sapiens_hsa030202.68644565
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.50170221
10Proteasome_Homo sapiens_hsa030502.44430596
11DNA replication_Homo sapiens_hsa030302.42537642
12Pyrimidine metabolism_Homo sapiens_hsa002402.25672125
13Mismatch repair_Homo sapiens_hsa034302.20359232
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.13540172
15Cardiac muscle contraction_Homo sapiens_hsa042602.04722471
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.99577659
17Base excision repair_Homo sapiens_hsa034101.72461971
18Sulfur metabolism_Homo sapiens_hsa009201.66959190
19Folate biosynthesis_Homo sapiens_hsa007901.66786770
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66479050
21Homologous recombination_Homo sapiens_hsa034401.63926777
22Propanoate metabolism_Homo sapiens_hsa006401.60014742
23SNARE interactions in vesicular transport_Homo sapiens_hsa041301.49315431
24Purine metabolism_Homo sapiens_hsa002301.47409717
25Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.47216491
26Nucleotide excision repair_Homo sapiens_hsa034201.45988663
27Spliceosome_Homo sapiens_hsa030401.38924237
28RNA degradation_Homo sapiens_hsa030181.31041028
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.21146402
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19759711
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.19513787
32Selenocompound metabolism_Homo sapiens_hsa004501.19095698
33Basal transcription factors_Homo sapiens_hsa030221.16861405
34Fatty acid elongation_Homo sapiens_hsa000621.16445040
35Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.13877379
36Asthma_Homo sapiens_hsa053101.13330205
37Arachidonic acid metabolism_Homo sapiens_hsa005901.12508549
38Non-homologous end-joining_Homo sapiens_hsa034501.11655729
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.09468030
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.08514709
41Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.07689122
42Galactose metabolism_Homo sapiens_hsa000521.05459307
43Metabolic pathways_Homo sapiens_hsa011000.97382244
44Type I diabetes mellitus_Homo sapiens_hsa049400.96959598
45Allograft rejection_Homo sapiens_hsa053300.94998846
46Pyruvate metabolism_Homo sapiens_hsa006200.93127091
47Autoimmune thyroid disease_Homo sapiens_hsa053200.92662978
48Carbon metabolism_Homo sapiens_hsa012000.89613044
49Fructose and mannose metabolism_Homo sapiens_hsa000510.89322434
50Linoleic acid metabolism_Homo sapiens_hsa005910.85255736
51Peroxisome_Homo sapiens_hsa041460.84812668
52Drug metabolism - other enzymes_Homo sapiens_hsa009830.82194737
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.79921251
54Graft-versus-host disease_Homo sapiens_hsa053320.79690456
55Other glycan degradation_Homo sapiens_hsa005110.77686366
56Phototransduction_Homo sapiens_hsa047440.76626717
57Glutathione metabolism_Homo sapiens_hsa004800.76049104
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.74977055
59Butanoate metabolism_Homo sapiens_hsa006500.74892397
60RNA transport_Homo sapiens_hsa030130.74719195
61Fatty acid degradation_Homo sapiens_hsa000710.73663348
62Fanconi anemia pathway_Homo sapiens_hsa034600.71926099
63Rheumatoid arthritis_Homo sapiens_hsa053230.66475939
64Caffeine metabolism_Homo sapiens_hsa002320.65131656
65Vibrio cholerae infection_Homo sapiens_hsa051100.63649848
66N-Glycan biosynthesis_Homo sapiens_hsa005100.61294640
67Cysteine and methionine metabolism_Homo sapiens_hsa002700.56758326
68One carbon pool by folate_Homo sapiens_hsa006700.54741560
69Tryptophan metabolism_Homo sapiens_hsa003800.54283673
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53364895
71Systemic lupus erythematosus_Homo sapiens_hsa053220.53018529
72Starch and sucrose metabolism_Homo sapiens_hsa005000.53006251
73Legionellosis_Homo sapiens_hsa051340.52171497
74Sulfur relay system_Homo sapiens_hsa041220.47909393
75Pancreatic secretion_Homo sapiens_hsa049720.47846125
76Fat digestion and absorption_Homo sapiens_hsa049750.46918317
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46848482
78Antigen processing and presentation_Homo sapiens_hsa046120.46589364
79Arginine and proline metabolism_Homo sapiens_hsa003300.45766467
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.44159399
81Steroid biosynthesis_Homo sapiens_hsa001000.43169704
82Nitrogen metabolism_Homo sapiens_hsa009100.40909706
83Pentose phosphate pathway_Homo sapiens_hsa000300.39516549
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.38191913
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37413212
86Herpes simplex infection_Homo sapiens_hsa051680.36040343
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35727608
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32477145
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.32206800
90Oocyte meiosis_Homo sapiens_hsa041140.31646824
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29400835
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29149649
93Mineral absorption_Homo sapiens_hsa049780.29132487
94Retinol metabolism_Homo sapiens_hsa008300.28541638
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28329462
96Collecting duct acid secretion_Homo sapiens_hsa049660.27592424
97p53 signaling pathway_Homo sapiens_hsa041150.27306557
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27306168
99Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25997906
100Vitamin digestion and absorption_Homo sapiens_hsa049770.25679924
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.25375158
102Cyanoamino acid metabolism_Homo sapiens_hsa004600.25068953
103Vitamin B6 metabolism_Homo sapiens_hsa007500.24696494
104Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24305785
105Primary immunodeficiency_Homo sapiens_hsa053400.23766508
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.23057684
107Cell cycle_Homo sapiens_hsa041100.22881292
108Chemical carcinogenesis_Homo sapiens_hsa052040.22682718
109Thyroid cancer_Homo sapiens_hsa052160.21897028
110beta-Alanine metabolism_Homo sapiens_hsa004100.20621226
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.20523779
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19581450
113Sphingolipid metabolism_Homo sapiens_hsa006000.18601740
114Biosynthesis of amino acids_Homo sapiens_hsa012300.18540758
115Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.17775371
116Intestinal immune network for IgA production_Homo sapiens_hsa046720.16795760
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.14315602
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.13839245
119Ether lipid metabolism_Homo sapiens_hsa005650.13693237
120Epstein-Barr virus infection_Homo sapiens_hsa051690.13011751
121Hematopoietic cell lineage_Homo sapiens_hsa046400.12993272
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.12178338
123mRNA surveillance pathway_Homo sapiens_hsa030150.09620402
124Regulation of autophagy_Homo sapiens_hsa041400.09290051
125Renin-angiotensin system_Homo sapiens_hsa046140.09038707

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