Rank | Gene Set | Z-score |
---|---|---|
1 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 4.06657755 |
2 | neuron cell-cell adhesion (GO:0007158) | 3.92254643 |
3 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 3.75789911 |
4 | pre-miRNA processing (GO:0031054) | 3.51221418 |
5 | axonal fasciculation (GO:0007413) | 3.39302250 |
6 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.37315748 |
7 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.33821131 |
8 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.32625634 |
9 | locomotory exploration behavior (GO:0035641) | 3.32413500 |
10 | histone H3-K36 demethylation (GO:0070544) | 3.31116636 |
11 | neuron recognition (GO:0008038) | 3.29101574 |
12 | histone H3-K4 trimethylation (GO:0080182) | 3.27219975 |
13 | vocalization behavior (GO:0071625) | 3.22554246 |
14 | embryonic camera-type eye morphogenesis (GO:0048596) | 3.22292575 |
15 | histone H3-K9 demethylation (GO:0033169) | 3.21208235 |
16 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.16597886 |
17 | dendritic spine morphogenesis (GO:0060997) | 3.15123478 |
18 | layer formation in cerebral cortex (GO:0021819) | 3.13936721 |
19 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.13670579 |
20 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.11124518 |
21 | presynaptic membrane assembly (GO:0097105) | 3.09718020 |
22 | negative regulation of DNA repair (GO:0045738) | 3.09575175 |
23 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.96255264 |
24 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.95976953 |
25 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.90399133 |
26 | protein localization to synapse (GO:0035418) | 2.87832137 |
27 | histone H3-K4 methylation (GO:0051568) | 2.87536519 |
28 | glutamate receptor signaling pathway (GO:0007215) | 2.85563901 |
29 | regulation of RNA export from nucleus (GO:0046831) | 2.83095917 |
30 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.82960311 |
31 | transmission of nerve impulse (GO:0019226) | 2.82808503 |
32 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.81886992 |
33 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.81600852 |
34 | neuronal stem cell maintenance (GO:0097150) | 2.80984975 |
35 | histone H3-K9 methylation (GO:0051567) | 2.80929407 |
36 | dendrite morphogenesis (GO:0048813) | 2.80482561 |
37 | histone lysine methylation (GO:0034968) | 2.80395495 |
38 | lateral sprouting from an epithelium (GO:0060601) | 2.79163426 |
39 | presynaptic membrane organization (GO:0097090) | 2.78673037 |
40 | branching involved in prostate gland morphogenesis (GO:0060442) | 2.76688596 |
41 | histone lysine demethylation (GO:0070076) | 2.73882284 |
42 | ectodermal placode formation (GO:0060788) | 2.72352662 |
43 | interkinetic nuclear migration (GO:0022027) | 2.72124660 |
44 | ear development (GO:0043583) | 2.70313598 |
45 | head development (GO:0060322) | 2.67095104 |
46 | auditory behavior (GO:0031223) | 2.66825282 |
47 | mitotic sister chromatid cohesion (GO:0007064) | 2.66271442 |
48 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.64176078 |
49 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.64176078 |
50 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.64176078 |
51 | Golgi to endosome transport (GO:0006895) | 2.64059459 |
52 | photoreceptor cell differentiation (GO:0046530) | 2.63963729 |
53 | eye photoreceptor cell differentiation (GO:0001754) | 2.63963729 |
54 | apical protein localization (GO:0045176) | 2.63158794 |
55 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.62914785 |
56 | detection of calcium ion (GO:0005513) | 2.60926624 |
57 | peptidyl-lysine methylation (GO:0018022) | 2.60432948 |
58 | axon ensheathment in central nervous system (GO:0032291) | 2.60282125 |
59 | central nervous system myelination (GO:0022010) | 2.60282125 |
60 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.60139495 |
61 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.59925308 |
62 | establishment of nucleus localization (GO:0040023) | 2.59436859 |
63 | protein targeting to Golgi (GO:0000042) | 2.59393274 |
64 | synaptic transmission, glutamatergic (GO:0035249) | 2.59308120 |
65 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.59052341 |
66 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.57961125 |
67 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.57860892 |
68 | synaptic vesicle exocytosis (GO:0016079) | 2.56596566 |
69 | positive regulation by host of viral transcription (GO:0043923) | 2.56011784 |
70 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.55942609 |
71 | regulation of histone H3-K27 methylation (GO:0061085) | 2.55796407 |
72 | regulation of protein polyubiquitination (GO:1902914) | 2.55160804 |
73 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.54317909 |
74 | histone demethylation (GO:0016577) | 2.54186492 |
75 | negative regulation of histone methylation (GO:0031061) | 2.52052213 |
76 | peripheral nervous system axon ensheathment (GO:0032292) | 2.51491882 |
77 | myelination in peripheral nervous system (GO:0022011) | 2.51491882 |
78 | neuronal action potential propagation (GO:0019227) | 2.50690811 |
79 | neuronal ion channel clustering (GO:0045161) | 2.48423161 |
80 | asymmetric protein localization (GO:0008105) | 2.47957308 |
81 | neuron-neuron synaptic transmission (GO:0007270) | 2.46964513 |
82 | heart morphogenesis (GO:0003007) | 2.46105655 |
83 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.45727452 |
84 | retina layer formation (GO:0010842) | 2.45236325 |
85 | innervation (GO:0060384) | 2.44565793 |
86 | embryonic eye morphogenesis (GO:0048048) | 2.43377748 |
87 | establishment of protein localization to Golgi (GO:0072600) | 2.42837502 |
88 | NLS-bearing protein import into nucleus (GO:0006607) | 2.42051995 |
89 | righting reflex (GO:0060013) | 2.42016911 |
90 | synaptic vesicle maturation (GO:0016188) | 2.41450277 |
91 | mechanosensory behavior (GO:0007638) | 2.41214731 |
92 | synaptic vesicle endocytosis (GO:0048488) | 2.39813096 |
93 | startle response (GO:0001964) | 2.39704720 |
94 | cell differentiation in hindbrain (GO:0021533) | 2.38491553 |
95 | positive regulation of synapse assembly (GO:0051965) | 2.37648890 |
96 | histone H3-K9 modification (GO:0061647) | 2.37172347 |
97 | exploration behavior (GO:0035640) | 2.36024938 |
98 | coronary vasculature morphogenesis (GO:0060977) | 2.35526196 |
99 | cerebellar granule cell differentiation (GO:0021707) | 2.35496679 |
100 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.33913396 |
101 | postsynaptic membrane organization (GO:0001941) | 2.33652952 |
102 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.33482561 |
103 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.33175175 |
104 | synapse assembly (GO:0007416) | 2.32856134 |
105 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.32551397 |
106 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) | 2.31942238 |
107 | histone H4-K16 acetylation (GO:0043984) | 2.31581989 |
108 | response to auditory stimulus (GO:0010996) | 2.31516814 |
109 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.31399673 |
110 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.30781386 |
111 | nucleus localization (GO:0051647) | 2.30563196 |
112 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.30052852 |
113 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.30052852 |
114 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.28997594 |
115 | regulation of postsynaptic membrane potential (GO:0060078) | 2.28477394 |
116 | membrane hyperpolarization (GO:0060081) | 2.28472513 |
117 | mating behavior (GO:0007617) | 2.28278632 |
118 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.28063762 |
119 | peptidyl-lysine trimethylation (GO:0018023) | 2.27863410 |
120 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.27738960 |
121 | synapse organization (GO:0050808) | 2.27654534 |
122 | nerve growth factor signaling pathway (GO:0038180) | 2.27381710 |
123 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.26860317 |
124 | paraxial mesoderm development (GO:0048339) | 2.26533975 |
125 | nuclear pore complex assembly (GO:0051292) | 2.26433319 |
126 | genitalia morphogenesis (GO:0035112) | 2.25819134 |
127 | cell migration in hindbrain (GO:0021535) | 2.25597691 |
128 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.25328510 |
129 | gastrulation with mouth forming second (GO:0001702) | 2.24893713 |
130 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.24725461 |
131 | regulation of axon guidance (GO:1902667) | 2.24678056 |
132 | artery development (GO:0060840) | 2.24063355 |
133 | protein K48-linked deubiquitination (GO:0071108) | 2.22641258 |
134 | long-term memory (GO:0007616) | 2.22390336 |
135 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.21204676 |
136 | regulation of histone H3-K4 methylation (GO:0051569) | 2.21039782 |
137 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.20457157 |
138 | biotin metabolic process (GO:0006768) | 2.20313047 |
139 | membrane depolarization during action potential (GO:0086010) | 2.19752830 |
140 | stress granule assembly (GO:0034063) | 2.19475728 |
141 | forebrain development (GO:0030900) | 2.18666351 |
142 | positive regulation of catenin import into nucleus (GO:0035413) | 2.18636523 |
143 | embryonic foregut morphogenesis (GO:0048617) | 2.18633013 |
144 | regulation of ARF protein signal transduction (GO:0032012) | 2.18609199 |
145 | regulation of synapse assembly (GO:0051963) | 2.18490585 |
146 | histone methylation (GO:0016571) | 2.18463601 |
147 | regulation of establishment of cell polarity (GO:2000114) | 2.18010950 |
148 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.17805605 |
149 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.17703219 |
150 | L-amino acid import (GO:0043092) | 2.17558349 |
151 | limb bud formation (GO:0060174) | 2.17281251 |
152 | cellular potassium ion homeostasis (GO:0030007) | 2.16615449 |
153 | protein demethylation (GO:0006482) | 2.16164134 |
154 | protein dealkylation (GO:0008214) | 2.16164134 |
155 | peptidyl-lysine dimethylation (GO:0018027) | 2.16053070 |
156 | long-term synaptic potentiation (GO:0060291) | 2.15511187 |
157 | regulation of gene silencing by RNA (GO:0060966) | 2.14902476 |
158 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.14902476 |
159 | regulation of gene silencing by miRNA (GO:0060964) | 2.14902476 |
160 | nonmotile primary cilium assembly (GO:0035058) | 2.14288649 |
161 | membrane depolarization (GO:0051899) | 2.13873499 |
162 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.13195862 |
163 | corticosteroid receptor signaling pathway (GO:0031958) | 2.12822309 |
164 | response to monoamine (GO:0071867) | 2.11642901 |
165 | response to catecholamine (GO:0071869) | 2.11642901 |
166 | morphogenesis of an epithelial sheet (GO:0002011) | 2.11187411 |
167 | negative regulation of neurotransmitter transport (GO:0051589) | 2.11133365 |
168 | cochlea development (GO:0090102) | 2.10475682 |
169 | establishment of spindle orientation (GO:0051294) | 2.09459935 |
170 | lung epithelial cell differentiation (GO:0060487) | 2.09451219 |
171 | phospholipid translocation (GO:0045332) | 2.09439142 |
172 | lipid translocation (GO:0034204) | 2.09439142 |
173 | limb development (GO:0060173) | 2.09401373 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.55946321 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.53524524 |
3 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.84244247 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.47315413 |
5 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.40290548 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.37224518 |
7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.31638626 |
8 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.31148902 |
9 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.21594679 |
10 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.18989725 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.17269340 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.17269340 |
13 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.15957532 |
14 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.15364706 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.04083995 |
16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.02678678 |
17 | * DROSHA_22980978_ChIP-Seq_HELA_Human | 1.98120160 |
18 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.97846171 |
19 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.97396078 |
20 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.95969822 |
21 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.94800689 |
22 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.92257319 |
23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.89984351 |
24 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.88474568 |
25 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.81831336 |
26 | FUS_26573619_Chip-Seq_HEK293_Human | 1.81644550 |
27 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.81255867 |
28 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.79450252 |
29 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.79358620 |
30 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.76054925 |
31 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.72145820 |
32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.72029709 |
33 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.68301507 |
34 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.68209746 |
35 | TP53_16413492_ChIP-PET_HCT116_Human | 1.66777595 |
36 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.66099009 |
37 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.65754973 |
38 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.64321828 |
39 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.63770158 |
40 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.63709038 |
41 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.60344764 |
42 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.60299172 |
43 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.60234813 |
44 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.60059303 |
45 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.59968308 |
46 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.59051133 |
47 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.58373942 |
48 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.57801373 |
49 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.55603119 |
50 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.53687052 |
51 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.53041519 |
52 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.52693090 |
53 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.50551118 |
54 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.50520352 |
55 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.49973625 |
56 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.48115942 |
57 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.46892164 |
58 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.45883132 |
59 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45874506 |
60 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.45325630 |
61 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.44494697 |
62 | * STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.43482097 |
63 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.42223162 |
64 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.41617448 |
65 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.39937007 |
66 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.39782180 |
67 | * FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.39135262 |
68 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.38545209 |
69 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.38052941 |
70 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.37524039 |
71 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.37359149 |
72 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.36523191 |
73 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.36299013 |
74 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.35903632 |
75 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.35289903 |
76 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.34683270 |
77 | EWS_26573619_Chip-Seq_HEK293_Human | 1.34415127 |
78 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.33884668 |
79 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.33162072 |
80 | * TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32314468 |
81 | * POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32314468 |
82 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.31907546 |
83 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.31018247 |
84 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.30849686 |
85 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.29280531 |
86 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.28969546 |
87 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.28797732 |
88 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.28285516 |
89 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.27083750 |
90 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.26558230 |
91 | AR_25329375_ChIP-Seq_VCAP_Human | 1.26360873 |
92 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.25914966 |
93 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.25738133 |
94 | * AR_19668381_ChIP-Seq_PC3_Human | 1.23897460 |
95 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.23761054 |
96 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.22370422 |
97 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21532277 |
98 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.20192793 |
99 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20152656 |
100 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.19801783 |
101 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.19149868 |
102 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.18878464 |
103 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.18476617 |
104 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.16742151 |
105 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.14617957 |
106 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.14063266 |
107 | * CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.13925169 |
108 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.13305744 |
109 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12986184 |
110 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.12811787 |
111 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.12120331 |
112 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.12081122 |
113 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11865049 |
114 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.11827431 |
115 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11102710 |
116 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.10746048 |
117 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10735120 |
118 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.09594500 |
119 | * FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.08720050 |
120 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.08507053 |
121 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.08022484 |
122 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.07836923 |
123 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07743580 |
124 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.07488215 |
125 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06436663 |
126 | * MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.05772161 |
127 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.05766000 |
128 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.04683782 |
129 | * FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.02961174 |
130 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.01656000 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 3.13836305 |
2 | MP0004859_abnormal_synaptic_plasticity | 2.97996383 |
3 | MP0003890_abnormal_embryonic-extraembry | 2.75803940 |
4 | MP0008057_abnormal_DNA_replication | 2.43945559 |
5 | MP0003787_abnormal_imprinting | 2.41952962 |
6 | MP0000569_abnormal_digit_pigmentation | 2.40025250 |
7 | MP0003635_abnormal_synaptic_transmissio | 2.35054705 |
8 | MP0009046_muscle_twitch | 2.19598341 |
9 | MP0005409_darkened_coat_color | 2.16269254 |
10 | MP0000778_abnormal_nervous_system | 2.15844430 |
11 | MP0005076_abnormal_cell_differentiation | 2.13524958 |
12 | MP0001486_abnormal_startle_reflex | 2.11602350 |
13 | MP0004270_analgesia | 2.01292024 |
14 | MP0005423_abnormal_somatic_nervous | 1.95890249 |
15 | MP0009745_abnormal_behavioral_response | 1.92612305 |
16 | MP0000383_abnormal_hair_follicle | 1.87821872 |
17 | MP0002064_seizures | 1.83702161 |
18 | MP0003122_maternal_imprinting | 1.79098533 |
19 | MP0002063_abnormal_learning/memory/cond | 1.75449824 |
20 | MP0004885_abnormal_endolymph | 1.75229794 |
21 | MP0002272_abnormal_nervous_system | 1.72530731 |
22 | MP0002822_catalepsy | 1.68741176 |
23 | MP0008961_abnormal_basal_metabolism | 1.68446632 |
24 | * MP0002572_abnormal_emotion/affect_behav | 1.67210216 |
25 | MP0003121_genomic_imprinting | 1.66258494 |
26 | MP0002909_abnormal_adrenal_gland | 1.63243437 |
27 | MP0002734_abnormal_mechanical_nocicepti | 1.55862080 |
28 | MP0001299_abnormal_eye_distance/ | 1.53790798 |
29 | MP0002184_abnormal_innervation | 1.50051158 |
30 | MP0002067_abnormal_sensory_capabilities | 1.47546448 |
31 | MP0001188_hyperpigmentation | 1.46362317 |
32 | MP0005171_absent_coat_pigmentation | 1.45427113 |
33 | MP0005551_abnormal_eye_electrophysiolog | 1.43917831 |
34 | MP0000566_synostosis | 1.42299929 |
35 | MP0003123_paternal_imprinting | 1.41875873 |
36 | MP0004145_abnormal_muscle_electrophysio | 1.41789482 |
37 | MP0004742_abnormal_vestibular_system | 1.41125639 |
38 | MP0003942_abnormal_urinary_system | 1.40960804 |
39 | MP0000631_abnormal_neuroendocrine_gland | 1.40712429 |
40 | MP0006072_abnormal_retinal_apoptosis | 1.38137709 |
41 | MP0008569_lethality_at_weaning | 1.36654758 |
42 | MP0002557_abnormal_social/conspecific_i | 1.36406692 |
43 | MP0004264_abnormal_extraembryonic_tissu | 1.36015886 |
44 | MP0002697_abnormal_eye_size | 1.34271496 |
45 | MP0009780_abnormal_chondrocyte_physiolo | 1.33243872 |
46 | MP0005646_abnormal_pituitary_gland | 1.32122138 |
47 | MP0000751_myopathy | 1.31871950 |
48 | MP0009703_decreased_birth_body | 1.30029214 |
49 | MP0003283_abnormal_digestive_organ | 1.29966926 |
50 | MP0001968_abnormal_touch/_nociception | 1.29927161 |
51 | MP0005645_abnormal_hypothalamus_physiol | 1.27936628 |
52 | MP0002882_abnormal_neuron_morphology | 1.27763213 |
53 | MP0001485_abnormal_pinna_reflex | 1.27697090 |
54 | MP0003115_abnormal_respiratory_system | 1.24785736 |
55 | MP0000955_abnormal_spinal_cord | 1.24679591 |
56 | MP0010678_abnormal_skin_adnexa | 1.24125214 |
57 | MP0002938_white_spotting | 1.23353157 |
58 | MP0001440_abnormal_grooming_behavior | 1.21595029 |
59 | MP0009672_abnormal_birth_weight | 1.21408357 |
60 | MP0002638_abnormal_pupillary_reflex | 1.20745639 |
61 | MP0002735_abnormal_chemical_nociception | 1.18055054 |
62 | MP0001501_abnormal_sleep_pattern | 1.14065293 |
63 | MP0002152_abnormal_brain_morphology | 1.13595988 |
64 | MP0001286_abnormal_eye_development | 1.12594296 |
65 | MP0005386_behavior/neurological_phenoty | 1.11369790 |
66 | MP0004924_abnormal_behavior | 1.11369790 |
67 | MP0003136_yellow_coat_color | 1.10942844 |
68 | MP0001984_abnormal_olfaction | 1.10276799 |
69 | MP0005623_abnormal_meninges_morphology | 1.09920583 |
70 | MP0002166_altered_tumor_susceptibility | 1.07622200 |
71 | MP0003861_abnormal_nervous_system | 1.07024699 |
72 | MP0002084_abnormal_developmental_patter | 1.06688109 |
73 | MP0003385_abnormal_body_wall | 1.06676084 |
74 | MP0006276_abnormal_autonomic_nervous | 1.06630890 |
75 | MP0003935_abnormal_craniofacial_develop | 1.05794399 |
76 | MP0003937_abnormal_limbs/digits/tail_de | 1.04516202 |
77 | MP0003315_abnormal_perineum_morphology | 1.04286965 |
78 | MP0003045_fibrosis | 1.04023067 |
79 | MP0004134_abnormal_chest_morphology | 1.01786567 |
80 | MP0003755_abnormal_palate_morphology | 1.01451355 |
81 | MP0003943_abnormal_hepatobiliary_system | 1.01438050 |
82 | MP0001346_abnormal_lacrimal_gland | 1.01121013 |
83 | MP0002752_abnormal_somatic_nervous | 1.00707040 |
84 | MP0001502_abnormal_circadian_rhythm | 1.00576710 |
85 | MP0002108_abnormal_muscle_morphology | 1.00438043 |
86 | MP0002837_dystrophic_cardiac_calcinosis | 1.00215023 |
87 | MP0002928_abnormal_bile_duct | 1.00125983 |
88 | MP0001970_abnormal_pain_threshold | 0.99237423 |
89 | MP0002751_abnormal_autonomic_nervous | 0.98503441 |
90 | MP0000920_abnormal_myelination | 0.98322194 |
91 | MP0004133_heterotaxia | 0.97485394 |
92 | MP0000432_abnormal_head_morphology | 0.97178542 |
93 | MP0002088_abnormal_embryonic_growth/wei | 0.96494463 |
94 | MP0004811_abnormal_neuron_physiology | 0.96221309 |
95 | MP0005220_abnormal_exocrine_pancreas | 0.95958106 |
96 | MP0008995_early_reproductive_senescence | 0.95501858 |
97 | MP0000049_abnormal_middle_ear | 0.94919433 |
98 | MP0003984_embryonic_growth_retardation | 0.94892311 |
99 | MP0008877_abnormal_DNA_methylation | 0.94330864 |
100 | MP0005394_taste/olfaction_phenotype | 0.94256637 |
101 | MP0005499_abnormal_olfactory_system | 0.94256637 |
102 | MP0001963_abnormal_hearing_physiology | 0.93985857 |
103 | MP0003938_abnormal_ear_development | 0.93355406 |
104 | MP0005253_abnormal_eye_physiology | 0.93151468 |
105 | MP0005503_abnormal_tendon_morphology | 0.92857136 |
106 | MP0000534_abnormal_ureter_morphology | 0.92269910 |
107 | MP0005187_abnormal_penis_morphology | 0.91432532 |
108 | MP0004233_abnormal_muscle_weight | 0.91212397 |
109 | MP0001177_atelectasis | 0.90051239 |
110 | MP0002009_preneoplasia | 0.89159284 |
111 | MP0000537_abnormal_urethra_morphology | 0.88824965 |
112 | * MP0002066_abnormal_motor_capabilities/c | 0.88323427 |
113 | MP0002733_abnormal_thermal_nociception | 0.87189661 |
114 | MP0000026_abnormal_inner_ear | 0.87053970 |
115 | MP0002249_abnormal_larynx_morphology | 0.86444157 |
116 | MP0003632_abnormal_nervous_system | 0.86245645 |
117 | MP0004272_abnormal_basement_membrane | 0.86224409 |
118 | MP0009250_abnormal_appendicular_skeleto | 0.85955056 |
119 | MP0002177_abnormal_outer_ear | 0.85765190 |
120 | MP0004215_abnormal_myocardial_fiber | 0.85749808 |
121 | MP0001529_abnormal_vocalization | 0.85063612 |
122 | MP0002116_abnormal_craniofacial_bone | 0.84872523 |
123 | MP0003634_abnormal_glial_cell | 0.84744540 |
124 | MP0002085_abnormal_embryonic_tissue | 0.84633738 |
125 | MP0002233_abnormal_nose_morphology | 0.84137492 |
126 | MP0002081_perinatal_lethality | 0.83842029 |
127 | MP0004085_abnormal_heartbeat | 0.83690766 |
128 | MP0009384_cardiac_valve_regurgitation | 0.83208132 |
129 | MP0000462_abnormal_digestive_system | 0.82432536 |
130 | MP0003941_abnormal_skin_development | 0.82405976 |
131 | MP0002092_abnormal_eye_morphology | 0.81929669 |
132 | MP0003137_abnormal_impulse_conducting | 0.81912090 |
133 | MP0002736_abnormal_nociception_after | 0.81893279 |
134 | MP0005380_embryogenesis_phenotype | 0.81858512 |
135 | MP0001672_abnormal_embryogenesis/_devel | 0.81858512 |
136 | MP0004185_abnormal_adipocyte_glucose | 0.81660812 |
137 | MP0000428_abnormal_craniofacial_morphol | 0.81291706 |
138 | MP0000733_abnormal_muscle_development | 0.79266303 |
139 | MP0003936_abnormal_reproductive_system | 0.78983945 |
140 | MP0010030_abnormal_orbit_morphology | 0.78522159 |
141 | MP0002114_abnormal_axial_skeleton | 0.77773357 |
142 | MP0001944_abnormal_pancreas_morphology | 0.77038091 |
143 | MP0004197_abnormal_fetal_growth/weight/ | 0.76113739 |
144 | MP0002089_abnormal_postnatal_growth/wei | 0.75928932 |
145 | MP0000538_abnormal_urinary_bladder | 0.75284962 |
146 | MP0002160_abnormal_reproductive_system | 0.74108632 |
147 | MP0010770_preweaning_lethality | 0.73074724 |
148 | MP0002082_postnatal_lethality | 0.73074724 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Midline defect of the nose (HP:0004122) | 2.88919570 |
2 | Focal seizures (HP:0007359) | 2.85894910 |
3 | Hepatoblastoma (HP:0002884) | 2.84853861 |
4 | Focal motor seizures (HP:0011153) | 2.81176591 |
5 | Febrile seizures (HP:0002373) | 2.80985768 |
6 | Abnormality of the ischium (HP:0003174) | 2.76292156 |
7 | Heterotopia (HP:0002282) | 2.70112240 |
8 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.56608480 |
9 | Atonic seizures (HP:0010819) | 2.51197521 |
10 | Broad face (HP:0000283) | 2.50798809 |
11 | Progressive cerebellar ataxia (HP:0002073) | 2.49630389 |
12 | Bronchomalacia (HP:0002780) | 2.49379725 |
13 | Hypoplastic ischia (HP:0003175) | 2.48795270 |
14 | Alacrima (HP:0000522) | 2.44460808 |
15 | Short 4th metacarpal (HP:0010044) | 2.39504760 |
16 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.39504760 |
17 | Epileptic encephalopathy (HP:0200134) | 2.39499301 |
18 | Aqueductal stenosis (HP:0002410) | 2.37374942 |
19 | Abnormality of the pubic bones (HP:0003172) | 2.35873124 |
20 | Truncal obesity (HP:0001956) | 2.34276566 |
21 | Broad-based gait (HP:0002136) | 2.29886022 |
22 | Anal stenosis (HP:0002025) | 2.28721602 |
23 | Abnormality of the nasal septum (HP:0000419) | 2.21885404 |
24 | Neonatal hypoglycemia (HP:0001998) | 2.20568823 |
25 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.19863577 |
26 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.19863577 |
27 | Long eyelashes (HP:0000527) | 2.15636057 |
28 | Volvulus (HP:0002580) | 2.15285364 |
29 | Macroorchidism (HP:0000053) | 2.14777638 |
30 | Drooling (HP:0002307) | 2.14347466 |
31 | Excessive salivation (HP:0003781) | 2.14347466 |
32 | Germ cell neoplasia (HP:0100728) | 2.14192786 |
33 | Decreased lacrimation (HP:0000633) | 2.13352528 |
34 | Narrow palate (HP:0000189) | 2.11486095 |
35 | Dysmetric saccades (HP:0000641) | 2.09289877 |
36 | Morphological abnormality of the middle ear (HP:0008609) | 2.09242500 |
37 | Hyperventilation (HP:0002883) | 2.08987338 |
38 | Gaze-evoked nystagmus (HP:0000640) | 2.08860984 |
39 | Flat acetabular roof (HP:0003180) | 2.08083333 |
40 | Cutaneous finger syndactyly (HP:0010554) | 2.07810405 |
41 | Anteriorly placed anus (HP:0001545) | 2.06754881 |
42 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.03314522 |
43 | Absent speech (HP:0001344) | 2.03248347 |
44 | Abnormality of the fingertips (HP:0001211) | 2.02083413 |
45 | Lip pit (HP:0100267) | 2.01498008 |
46 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.00874007 |
47 | Genetic anticipation (HP:0003743) | 2.00700491 |
48 | Tracheomalacia (HP:0002779) | 1.99335714 |
49 | Broad palm (HP:0001169) | 1.97507955 |
50 | Widely spaced teeth (HP:0000687) | 1.94142149 |
51 | Sparse lateral eyebrow (HP:0005338) | 1.94018266 |
52 | Abnormal hair whorl (HP:0010721) | 1.93837441 |
53 | Laryngomalacia (HP:0001601) | 1.93530964 |
54 | Anophthalmia (HP:0000528) | 1.92910048 |
55 | Asymmetry of the thorax (HP:0001555) | 1.92856548 |
56 | Trigonocephaly (HP:0000243) | 1.89857382 |
57 | Genital tract atresia (HP:0001827) | 1.88764042 |
58 | Supernumerary ribs (HP:0005815) | 1.88718435 |
59 | Abnormality of the corticospinal tract (HP:0002492) | 1.88678872 |
60 | Obsessive-compulsive behavior (HP:0000722) | 1.88635705 |
61 | Myelomeningocele (HP:0002475) | 1.88110765 |
62 | Truncal ataxia (HP:0002078) | 1.86125151 |
63 | Thick eyebrow (HP:0000574) | 1.84434233 |
64 | Vaginal atresia (HP:0000148) | 1.82303693 |
65 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.81513557 |
66 | Abnormality of incisor morphology (HP:0011063) | 1.80721789 |
67 | Abnormality of the aortic arch (HP:0012303) | 1.79638752 |
68 | Action tremor (HP:0002345) | 1.77871464 |
69 | Abnormality of the nasolacrimal system (HP:0000614) | 1.77851747 |
70 | Septate vagina (HP:0001153) | 1.77178333 |
71 | Cutaneous syndactyly (HP:0012725) | 1.76522951 |
72 | Abnormality of the 4th metacarpal (HP:0010012) | 1.76369335 |
73 | Oligodactyly (hands) (HP:0001180) | 1.76246855 |
74 | Abnormality of the labia minora (HP:0012880) | 1.75813581 |
75 | Synophrys (HP:0000664) | 1.75755302 |
76 | Overgrowth (HP:0001548) | 1.75602076 |
77 | Diastasis recti (HP:0001540) | 1.75116573 |
78 | Bell-shaped thorax (HP:0001591) | 1.74829175 |
79 | Cupped ear (HP:0000378) | 1.73442009 |
80 | Overlapping toe (HP:0001845) | 1.73290830 |
81 | Absence seizures (HP:0002121) | 1.72139438 |
82 | Hypoplastic labia majora (HP:0000059) | 1.71874296 |
83 | Deep philtrum (HP:0002002) | 1.70705254 |
84 | Narrow nasal bridge (HP:0000446) | 1.70504716 |
85 | Abnormality of the epiphyses of the hand (HP:0005924) | 1.70172992 |
86 | Abnormality of the lacrimal duct (HP:0011481) | 1.70057095 |
87 | Intellectual disability, moderate (HP:0002342) | 1.69860166 |
88 | Aplasia involving bones of the extremities (HP:0009825) | 1.69579266 |
89 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.69579266 |
90 | Aplasia of the phalanges of the hand (HP:0009802) | 1.69579266 |
91 | Bifid scrotum (HP:0000048) | 1.69401653 |
92 | Broad thumb (HP:0011304) | 1.69233578 |
93 | Neoplasm of the oral cavity (HP:0100649) | 1.68794316 |
94 | Shallow orbits (HP:0000586) | 1.68742336 |
95 | Exotropia (HP:0000577) | 1.68552034 |
96 | Hyperacusis (HP:0010780) | 1.68448507 |
97 | Missing ribs (HP:0000921) | 1.67808850 |
98 | Overriding aorta (HP:0002623) | 1.67741807 |
99 | Abnormality of the diencephalon (HP:0010662) | 1.66988373 |
100 | Abnormality of the radial head (HP:0003995) | 1.66488094 |
101 | Limited elbow extension (HP:0001377) | 1.66422223 |
102 | Blue irides (HP:0000635) | 1.66399119 |
103 | Gonadotropin excess (HP:0000837) | 1.66009064 |
104 | Abnormality of the parietal bone (HP:0002696) | 1.65352761 |
105 | Hypoplasia of the maxilla (HP:0000327) | 1.65314245 |
106 | Shawl scrotum (HP:0000049) | 1.65313272 |
107 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.64347638 |
108 | Thyroid carcinoma (HP:0002890) | 1.63694333 |
109 | Scanning speech (HP:0002168) | 1.63529179 |
110 | Depressed nasal tip (HP:0000437) | 1.63200245 |
111 | Smooth philtrum (HP:0000319) | 1.63121352 |
112 | Broad metatarsal (HP:0001783) | 1.63103584 |
113 | Renovascular hypertension (HP:0100817) | 1.62742722 |
114 | Hypoplastic iliac wings (HP:0002866) | 1.62688105 |
115 | Dislocated radial head (HP:0003083) | 1.62600496 |
116 | Abnormality of salivation (HP:0100755) | 1.62584522 |
117 | Abnormality of secondary sexual hair (HP:0009888) | 1.61701264 |
118 | Abnormality of the axillary hair (HP:0100134) | 1.61701264 |
119 | Flat cornea (HP:0007720) | 1.61089936 |
120 | Menstrual irregularities (HP:0000858) | 1.60159691 |
121 | Increased nuchal translucency (HP:0010880) | 1.59878010 |
122 | Hypopigmentation of the fundus (HP:0007894) | 1.59032457 |
123 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 1.58616868 |
124 | Abnormality of the labia majora (HP:0012881) | 1.58420356 |
125 | Absent eyebrow (HP:0002223) | 1.58031854 |
126 | High anterior hairline (HP:0009890) | 1.57329193 |
127 | Hypoplastic nipples (HP:0002557) | 1.57142172 |
128 | Insidious onset (HP:0003587) | 1.57036739 |
129 | Termporal pattern (HP:0011008) | 1.57036739 |
130 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.56613015 |
131 | Hypoplastic ilia (HP:0000946) | 1.56101474 |
132 | Low anterior hairline (HP:0000294) | 1.56065918 |
133 | Abnormality involving the epiphyses of the upper limbs (HP:0003839) | 1.56046492 |
134 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.56002765 |
135 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.55992824 |
136 | Thickened helices (HP:0000391) | 1.55892020 |
137 | 11 pairs of ribs (HP:0000878) | 1.55452655 |
138 | Short metatarsal (HP:0010743) | 1.54682064 |
139 | Gastroesophageal reflux (HP:0002020) | 1.54610849 |
140 | Chronic hepatic failure (HP:0100626) | 1.54397707 |
141 | Wide nose (HP:0000445) | 1.54176006 |
142 | Papillary thyroid carcinoma (HP:0002895) | 1.54014608 |
143 | Abnormality of the parathyroid morphology (HP:0011766) | 1.54010288 |
144 | Renal hypoplasia (HP:0000089) | 1.53513232 |
145 | Broad finger (HP:0001500) | 1.53064577 |
146 | Dialeptic seizures (HP:0011146) | 1.52406002 |
147 | Elfin facies (HP:0004428) | 1.51605924 |
148 | Gait imbalance (HP:0002141) | 1.51321846 |
149 | Vesicoureteral reflux (HP:0000076) | 1.51281402 |
150 | Tubulointerstitial nephritis (HP:0001970) | 1.50782971 |
151 | Neoplasm of the heart (HP:0100544) | 1.50279591 |
152 | Mixed hearing impairment (HP:0000410) | 1.50250468 |
153 | Sacral dimple (HP:0000960) | 1.50009298 |
154 | Urinary urgency (HP:0000012) | 1.49599078 |
155 | Renal duplication (HP:0000075) | 1.48773713 |
156 | Absent frontal sinuses (HP:0002688) | 1.48353289 |
157 | Ankle clonus (HP:0011448) | 1.48307306 |
158 | Aplasia cutis congenita (HP:0001057) | 1.48127988 |
159 | Protruding tongue (HP:0010808) | 1.48070817 |
160 | Vertebral arch anomaly (HP:0008438) | 1.47259643 |
161 | Bifid tongue (HP:0010297) | 1.46882403 |
162 | Skull defect (HP:0001362) | 1.46627097 |
163 | Hemiparesis (HP:0001269) | 1.45285662 |
164 | Tapered finger (HP:0001182) | 1.44923333 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K4 | 2.99998599 |
2 | TRIB3 | 2.99818768 |
3 | NTRK3 | 2.92631950 |
4 | CASK | 2.51287899 |
5 | FGFR2 | 2.50194998 |
6 | PNCK | 2.49926876 |
7 | CAMK1G | 2.42329454 |
8 | EEF2K | 2.41781235 |
9 | TNIK | 2.29009246 |
10 | NTRK2 | 2.17810889 |
11 | MAP3K10 | 2.04521395 |
12 | EPHA4 | 2.02268119 |
13 | STK39 | 1.93146784 |
14 | MARK1 | 1.89562032 |
15 | WNK1 | 1.88295435 |
16 | MAPK13 | 1.77875241 |
17 | CAMK1D | 1.73322323 |
18 | PKN2 | 1.70225068 |
19 | FGFR3 | 1.66769338 |
20 | DMPK | 1.63687338 |
21 | FGFR4 | 1.63658701 |
22 | SIK2 | 1.62984414 |
23 | CDK12 | 1.58848600 |
24 | BRD4 | 1.56953615 |
25 | MAP2K7 | 1.47641358 |
26 | FRK | 1.33190359 |
27 | PKN1 | 1.32681132 |
28 | SGK2 | 1.23146905 |
29 | TYRO3 | 1.21905424 |
30 | SGK223 | 1.19976022 |
31 | SGK494 | 1.19976022 |
32 | NLK | 1.17445148 |
33 | BCR | 1.15967236 |
34 | UHMK1 | 1.15312185 |
35 | CDK3 | 1.13759003 |
36 | TNK2 | 1.11496482 |
37 | CSNK1A1L | 1.11020017 |
38 | ICK | 1.09740197 |
39 | CDC42BPA | 1.08446963 |
40 | OXSR1 | 1.05454203 |
41 | MINK1 | 1.03271384 |
42 | PAK6 | 1.03047783 |
43 | SIK1 | 1.01801624 |
44 | NEK6 | 1.01416884 |
45 | MARK2 | 1.01408116 |
46 | PDGFRA | 0.99018361 |
47 | AKT3 | 0.98010631 |
48 | SGK3 | 0.97348728 |
49 | RIPK1 | 0.96420655 |
50 | NTRK1 | 0.95155114 |
51 | INSRR | 0.93686343 |
52 | PLK2 | 0.92701696 |
53 | ERBB2 | 0.91919792 |
54 | MAP3K9 | 0.91364344 |
55 | MAPK15 | 0.91101986 |
56 | CDK5 | 0.87649698 |
57 | SGK1 | 0.87447619 |
58 | PDGFRB | 0.87271975 |
59 | PHKG2 | 0.86809628 |
60 | PHKG1 | 0.86809628 |
61 | PAK3 | 0.86419273 |
62 | STK38L | 0.86300951 |
63 | CSNK1G2 | 0.85795028 |
64 | CHUK | 0.84082951 |
65 | LATS1 | 0.83280903 |
66 | CAMKK1 | 0.81367270 |
67 | WNK4 | 0.81356182 |
68 | PASK | 0.80540471 |
69 | MAP2K4 | 0.80204314 |
70 | DYRK1A | 0.79137697 |
71 | PRKCE | 0.79137141 |
72 | RPS6KB2 | 0.78661907 |
73 | CDK7 | 0.77890258 |
74 | ROCK2 | 0.76710120 |
75 | DDR2 | 0.76253493 |
76 | MAP3K7 | 0.75939995 |
77 | CSNK1G1 | 0.74821823 |
78 | LMTK2 | 0.74818113 |
79 | KSR1 | 0.74407860 |
80 | ERBB3 | 0.72649947 |
81 | RET | 0.72488063 |
82 | PRKCH | 0.71376835 |
83 | CAMK2A | 0.70785670 |
84 | PRKD3 | 0.70655472 |
85 | PRKAA1 | 0.70448565 |
86 | FGR | 0.70335648 |
87 | MAPK10 | 0.69714112 |
88 | PIK3CA | 0.68286952 |
89 | DAPK2 | 0.67852332 |
90 | STK11 | 0.67825082 |
91 | MKNK2 | 0.66942102 |
92 | RPS6KB1 | 0.65984528 |
93 | MKNK1 | 0.61806259 |
94 | MAPKAPK5 | 0.61806017 |
95 | EPHA3 | 0.61491880 |
96 | FER | 0.61298341 |
97 | CSNK1E | 0.60397078 |
98 | CSNK1G3 | 0.60017281 |
99 | GSK3B | 0.59794328 |
100 | MAP3K6 | 0.59546699 |
101 | TAF1 | 0.59356785 |
102 | CAMK4 | 0.59206876 |
103 | PRKD1 | 0.59000852 |
104 | MAP3K2 | 0.58720899 |
105 | ROCK1 | 0.58604005 |
106 | MELK | 0.58562803 |
107 | PRPF4B | 0.57993330 |
108 | CSNK1D | 0.57903891 |
109 | MAPK8 | 0.57418342 |
110 | CAMK2B | 0.56099476 |
111 | CAMK1 | 0.55926647 |
112 | ATM | 0.55550109 |
113 | FGFR1 | 0.55388331 |
114 | WNK3 | 0.55234395 |
115 | NUAK1 | 0.55095050 |
116 | PRKG1 | 0.54901246 |
117 | MAPK14 | 0.54655193 |
118 | HIPK2 | 0.54347752 |
119 | BMPR1B | 0.53906674 |
120 | RPS6KA3 | 0.53302555 |
121 | PRKDC | 0.52528359 |
122 | FYN | 0.52120779 |
123 | TAOK1 | 0.52036971 |
124 | MTOR | 0.51927180 |
125 | ADRBK1 | 0.51119638 |
126 | RPS6KA2 | 0.50420902 |
127 | CAMK2D | 0.50151521 |
128 | EPHB2 | 0.50119212 |
129 | PRKCZ | 0.49912049 |
130 | CDK2 | 0.49095249 |
131 | CDK1 | 0.48724948 |
132 | AKT1 | 0.45716519 |
133 | STK38 | 0.45209572 |
134 | PRKAA2 | 0.43759170 |
135 | LATS2 | 0.42232642 |
136 | YES1 | 0.41075949 |
137 | CHEK1 | 0.39078084 |
138 | ATR | 0.38706003 |
139 | MAPK1 | 0.38034495 |
140 | PAK2 | 0.36874335 |
141 | DYRK1B | 0.35746627 |
142 | MAP2K2 | 0.34735141 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.84559378 |
2 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.20611251 |
3 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.14744413 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.10741721 |
5 | GABAergic synapse_Homo sapiens_hsa04727 | 2.08756697 |
6 | Morphine addiction_Homo sapiens_hsa05032 | 2.08659646 |
7 | Taste transduction_Homo sapiens_hsa04742 | 1.80348845 |
8 | Long-term potentiation_Homo sapiens_hsa04720 | 1.75917832 |
9 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.72858880 |
10 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.71948401 |
11 | Olfactory transduction_Homo sapiens_hsa04740 | 1.70586114 |
12 | Axon guidance_Homo sapiens_hsa04360 | 1.67249294 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.66614425 |
14 | Phototransduction_Homo sapiens_hsa04744 | 1.65047379 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.64779327 |
16 | Renin secretion_Homo sapiens_hsa04924 | 1.59068965 |
17 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.58790209 |
18 | Insulin secretion_Homo sapiens_hsa04911 | 1.55640497 |
19 | Salivary secretion_Homo sapiens_hsa04970 | 1.55624313 |
20 | Long-term depression_Homo sapiens_hsa04730 | 1.53261983 |
21 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.46733177 |
22 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.42939128 |
23 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.40368819 |
24 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.38663302 |
25 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.37137755 |
26 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.34179396 |
27 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.33638510 |
28 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.33502480 |
29 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.30370004 |
30 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.30299208 |
31 | Cocaine addiction_Homo sapiens_hsa05030 | 1.30274073 |
32 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.26581435 |
33 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.24289259 |
34 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.22782476 |
35 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.22325392 |
36 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.22156340 |
37 | Melanogenesis_Homo sapiens_hsa04916 | 1.21440254 |
38 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.21026428 |
39 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.19342035 |
40 | Thyroid cancer_Homo sapiens_hsa05216 | 1.18672567 |
41 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.15791095 |
42 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.15234174 |
43 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.13451095 |
44 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.12677264 |
45 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.12405736 |
46 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.10934709 |
47 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.09858033 |
48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.09555121 |
49 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.09245183 |
50 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.08067758 |
51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08029413 |
52 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06369637 |
53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.05852149 |
54 | Gap junction_Homo sapiens_hsa04540 | 1.04818426 |
55 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.04675394 |
56 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.02252995 |
57 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.97961828 |
58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97848718 |
59 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.97838014 |
60 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.96624213 |
61 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.96260441 |
62 | Glioma_Homo sapiens_hsa05214 | 0.95672762 |
63 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94213204 |
64 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.90750888 |
65 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.89423447 |
66 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.88788165 |
67 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.87914438 |
68 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.87144166 |
69 | Endometrial cancer_Homo sapiens_hsa05213 | 0.86656026 |
70 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.86531579 |
71 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.85538601 |
72 | ABC transporters_Homo sapiens_hsa02010 | 0.84650462 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.84254814 |
74 | Colorectal cancer_Homo sapiens_hsa05210 | 0.83032246 |
75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.81861935 |
76 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.81666221 |
77 | Alcoholism_Homo sapiens_hsa05034 | 0.81580178 |
78 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.79823608 |
79 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.76940351 |
80 | Lysine degradation_Homo sapiens_hsa00310 | 0.75722083 |
81 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.75585308 |
82 | Focal adhesion_Homo sapiens_hsa04510 | 0.74958352 |
83 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.74672010 |
84 | Tight junction_Homo sapiens_hsa04530 | 0.73873924 |
85 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.72176040 |
86 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.72097875 |
87 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.69977191 |
88 | Prostate cancer_Homo sapiens_hsa05215 | 0.69243533 |
89 | Pathways in cancer_Homo sapiens_hsa05200 | 0.67485177 |
90 | Melanoma_Homo sapiens_hsa05218 | 0.66771376 |
91 | Adherens junction_Homo sapiens_hsa04520 | 0.65527068 |
92 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.65501954 |
93 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.64612007 |
94 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.63878595 |
95 | Circadian rhythm_Homo sapiens_hsa04710 | 0.62975382 |
96 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.60916834 |
97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59810906 |
98 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.59666781 |
99 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.59566836 |
100 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.58784088 |
101 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.58256769 |
102 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.57745677 |
103 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.56879009 |
104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.56874236 |
105 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.56045588 |
106 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.55225070 |
107 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.55057332 |
108 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.54991121 |
109 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.54800985 |
110 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54395952 |
111 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.52823288 |
112 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.52525776 |
113 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.52504664 |
114 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.52011179 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.50399277 |
116 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.49225698 |
117 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48851445 |
118 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.48452982 |