CHODL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1aggressive behavior (GO:0002118)6.96969326
2behavioral response to ethanol (GO:0048149)6.58178608
3exogenous drug catabolic process (GO:0042738)5.54312366
4adult feeding behavior (GO:0008343)5.51917207
5neurotransmitter biosynthetic process (GO:0042136)5.06532253
6phenol-containing compound catabolic process (GO:0019336)4.74298980
7regulation of neurotransmitter uptake (GO:0051580)4.61902435
8behavioral response to nicotine (GO:0035095)4.50469278
9neurofilament cytoskeleton organization (GO:0060052)4.47519827
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.40812478
11positive regulation of fibroblast migration (GO:0010763)4.36259703
12synaptic transmission, dopaminergic (GO:0001963)4.29776084
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.27594527
14positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.25582097
15drug catabolic process (GO:0042737)4.18413098
16pyrimidine nucleobase catabolic process (GO:0006208)4.15540870
17negative regulation of heart rate (GO:0010459)4.05629895
18neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)4.04267118
19neurotransmitter secretion (GO:0007269)4.00154977
20neuromuscular synaptic transmission (GO:0007274)4.00136596
21epithelial cilium movement (GO:0003351)3.84031493
22protein polyglutamylation (GO:0018095)3.81933552
23sympathetic nervous system development (GO:0048485)3.80520265
24regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.80474606
25regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.80474606
26negative regulation of calcium ion transport into cytosol (GO:0010523)3.77088873
27synaptic transmission, cholinergic (GO:0007271)3.74720298
28base-excision repair, AP site formation (GO:0006285)3.74615559
29neurotransmitter catabolic process (GO:0042135)3.69186178
30regulation of glutamate receptor signaling pathway (GO:1900449)3.68013621
31neuron cell-cell adhesion (GO:0007158)3.66693891
32regulation of response to food (GO:0032095)3.63279260
33positive regulation of action potential (GO:0045760)3.59179252
34neurotransmitter metabolic process (GO:0042133)3.57491797
35presynaptic membrane assembly (GO:0097105)3.52851819
36positive regulation of synaptic transmission, GABAergic (GO:0032230)3.51302571
37retinal ganglion cell axon guidance (GO:0031290)3.50511654
38muscle filament sliding (GO:0030049)3.50508571
39actin-myosin filament sliding (GO:0033275)3.50508571
40regulation of meiosis I (GO:0060631)3.48611870
41negative regulation of neurotransmitter transport (GO:0051589)3.47408806
42sequestering of actin monomers (GO:0042989)3.46662786
43postsynaptic membrane organization (GO:0001941)3.40896449
44cochlea development (GO:0090102)3.32929510
45synaptic vesicle exocytosis (GO:0016079)3.32561965
46regulation of short-term neuronal synaptic plasticity (GO:0048172)3.32528384
47cell migration in hindbrain (GO:0021535)3.32385979
48G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.31610729
49sequestering of extracellular ligand from receptor (GO:0035581)3.30897772
50RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24168143
51tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24168143
52nucleobase catabolic process (GO:0046113)3.22932771
53cilium movement (GO:0003341)3.13778862
54arginine catabolic process (GO:0006527)3.13031132
55extracellular regulation of signal transduction (GO:1900115)3.11840296
56extracellular negative regulation of signal transduction (GO:1900116)3.11840296
57microtubule severing (GO:0051013)3.11801626
58positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.10940364
59neurotransmitter transport (GO:0006836)3.10477784
60actin-mediated cell contraction (GO:0070252)3.09742963
61mesenchymal-epithelial cell signaling (GO:0060638)3.09735276
62DNA double-strand break processing (GO:0000729)3.09660026
63axonemal dynein complex assembly (GO:0070286)3.09561068
64protein localization to synapse (GO:0035418)3.08231945
65cellular response to ammonium ion (GO:0071242)3.07879499
66presynaptic membrane organization (GO:0097090)3.07875401
67regulation of neurotransmitter levels (GO:0001505)3.07592451
68oxygen transport (GO:0015671)3.06441159
69negative regulation of receptor activity (GO:2000272)3.06062446
70regulation of synaptic vesicle exocytosis (GO:2000300)3.05551037
71positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-3.05164964
72axonal fasciculation (GO:0007413)3.05108201
73transmission of nerve impulse (GO:0019226)3.04544883
74intraciliary transport (GO:0042073)3.03700200
75positive regulation of response to nutrient levels (GO:0032109)3.02110535
76positive regulation of response to extracellular stimulus (GO:0032106)3.02110535
77vocalization behavior (GO:0071625)3.01669004
78neuron recognition (GO:0008038)2.99138387
79calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.98768371
80myelination in peripheral nervous system (GO:0022011)2.97071212
81peripheral nervous system axon ensheathment (GO:0032292)2.97071212
82skeletal muscle contraction (GO:0003009)2.96197831
83regulation of appetite (GO:0032098)2.94963616
84peptidyl-cysteine modification (GO:0018198)2.94807735
85regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.93626221
86chromatin remodeling at centromere (GO:0031055)2.92584374
87negative regulation of microtubule polymerization (GO:0031115)2.92005248
88regulation of feeding behavior (GO:0060259)2.90952601
89regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.89667675
90regulation of neurotransmitter transport (GO:0051588)2.88667664
91synaptic vesicle maturation (GO:0016188)2.87238306
92negative regulation of transcription regulatory region DNA binding (GO:2000678)2.86644779
93ganglion development (GO:0061548)2.86641891
94limb bud formation (GO:0060174)2.85920859
95CENP-A containing nucleosome assembly (GO:0034080)2.85562616
96DNA replication-dependent nucleosome organization (GO:0034723)2.84727102
97DNA replication-dependent nucleosome assembly (GO:0006335)2.84727102
98positive regulation of sodium ion transmembrane transport (GO:1902307)2.84453048
99regulation of sarcomere organization (GO:0060297)2.82843036
100central nervous system neuron development (GO:0021954)2.81817038
101otic vesicle formation (GO:0030916)2.81389625
102myoblast migration (GO:0051451)2.80712535
103catecholamine transport (GO:0051937)2.78488132
104exploration behavior (GO:0035640)2.76794054
105maternal behavior (GO:0042711)2.76130081
106regulation of vesicle fusion (GO:0031338)2.75970576
107parturition (GO:0007567)2.75854243
108microtubule depolymerization (GO:0007019)2.75094558
109nonmotile primary cilium assembly (GO:0035058)2.74024180
110activation of protein kinase A activity (GO:0034199)2.73145195
111regulation of synaptic transmission, dopaminergic (GO:0032225)2.72838572
112bone trabecula formation (GO:0060346)2.72615655
113regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.72220456
114positive regulation of gastrulation (GO:2000543)2.71838572
115ATP hydrolysis coupled proton transport (GO:0015991)2.70084329
116energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.70084329
117axon extension involved in axon guidance (GO:0048846)2.70041519
118neuron projection extension involved in neuron projection guidance (GO:1902284)2.70041519
119positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.69914178
120olfactory bulb development (GO:0021772)2.69319456
121negative regulation of DNA repair (GO:0045738)2.68375466
122neuron-neuron synaptic transmission (GO:0007270)2.65339259
123negative regulation of axon guidance (GO:1902668)2.65011622
124positive regulation of meiosis (GO:0045836)2.64207336
125positive regulation of synapse assembly (GO:0051965)2.64189011
126regulation of transmission of nerve impulse (GO:0051969)2.64154662
127chaperone-mediated protein transport (GO:0072321)2.64021999
128regulation of uterine smooth muscle contraction (GO:0070472)2.63322525
129positive regulation of heart rate (GO:0010460)2.63238334
130head development (GO:0060322)2.63069934
131cellular response to prostaglandin stimulus (GO:0071379)2.61814125
132mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.61119031
133negative regulation of axon extension involved in axon guidance (GO:0048843)2.61046717
134myoblast fusion (GO:0007520)2.59731388
135dendritic spine morphogenesis (GO:0060997)2.59039525
136positive regulation of mitochondrial fission (GO:0090141)2.58370062
137response to pain (GO:0048265)2.57917485
138neuronal ion channel clustering (GO:0045161)2.57597519
139protein neddylation (GO:0045116)2.57548456
140auditory behavior (GO:0031223)2.57387640
141nitric oxide mediated signal transduction (GO:0007263)2.56029545
142cellular response to estradiol stimulus (GO:0071392)2.55896979
143substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.54713325
144substrate-independent telencephalic tangential migration (GO:0021826)2.54713325
145neuromuscular process controlling posture (GO:0050884)2.54006943
146mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.53684756
147establishment of mitochondrion localization (GO:0051654)2.53634947
148neuron fate determination (GO:0048664)2.53299715
149proline transport (GO:0015824)2.52827586
150DNA integration (GO:0015074)2.52608369
151cilium morphogenesis (GO:0060271)2.52480522
152protein localization to cilium (GO:0061512)2.51602768
153DNA replication-independent nucleosome organization (GO:0034724)2.50749166
154DNA replication-independent nucleosome assembly (GO:0006336)2.50749166
155positive regulation of amine transport (GO:0051954)2.48818039
156neural tube formation (GO:0001841)2.47725149
157positive regulation of neurotransmitter transport (GO:0051590)2.47318944
158positive regulation of uterine smooth muscle contraction (GO:0070474)2.46713309
159cilium assembly (GO:0042384)2.46456719
160opioid receptor signaling pathway (GO:0038003)2.45955402
161positive regulation of meiotic cell cycle (GO:0051446)2.45518371
162G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.45422630
163energy coupled proton transport, down electrochemical gradient (GO:0015985)2.45321115
164ATP synthesis coupled proton transport (GO:0015986)2.45321115
165DNA replication checkpoint (GO:0000076)2.45291530
166central nervous system projection neuron axonogenesis (GO:0021952)2.43543037
167cilium organization (GO:0044782)2.43130847
168mechanosensory behavior (GO:0007638)2.42995800
169G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.42461860
170glycosphingolipid biosynthetic process (GO:0006688)2.39970514
171axon extension (GO:0048675)2.39599894
172myotube cell development (GO:0014904)2.38412175
173organelle disassembly (GO:1903008)2.37326904
174regulation of cilium movement (GO:0003352)2.36143490
175short-term memory (GO:0007614)2.35005402
176axoneme assembly (GO:0035082)2.34916853
177negative regulation of catecholamine secretion (GO:0033604)2.34507593
178regulation of action potential (GO:0098900)2.34227923
179centriole replication (GO:0007099)2.34169852
180mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.33256092
181mitochondrial respiratory chain complex I assembly (GO:0032981)2.33256092
182NADH dehydrogenase complex assembly (GO:0010257)2.33256092
183pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.32350216
184neurotransmitter-gated ion channel clustering (GO:0072578)2.31441976
185dopamine biosynthetic process (GO:0042416)2.30989517
186kidney morphogenesis (GO:0060993)2.29754677
187regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29123610

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.34551301
2GBX2_23144817_ChIP-Seq_PC3_Human3.77633617
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.36445951
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.18709182
5SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.91675359
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.86817851
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.83684047
8SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.82666668
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.81403650
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.81403650
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.77642052
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.76205608
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.70765012
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.64668297
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.59926961
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.42564843
17TAF15_26573619_Chip-Seq_HEK293_Human2.35084720
18VDR_22108803_ChIP-Seq_LS180_Human2.34789079
19BMI1_23680149_ChIP-Seq_NPCS_Mouse2.22666439
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21892937
21CDX2_19796622_ChIP-Seq_MESCs_Mouse2.17876860
22TRIM28_21343339_ChIP-Seq_HEK293_Human2.10629022
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.01112127
24AR_21572438_ChIP-Seq_LNCaP_Human2.00532382
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.00112021
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98150893
27SUZ12_27294783_Chip-Seq_ESCs_Mouse1.97411507
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96509689
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.95700641
30EZH2_27294783_Chip-Seq_ESCs_Mouse1.92140237
31WT1_19549856_ChIP-ChIP_CCG9911_Human1.91905493
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.91887577
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.91594237
34HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.89344069
35* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.88448117
36KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.83379017
37P300_19829295_ChIP-Seq_ESCs_Human1.80843659
38REST_21632747_ChIP-Seq_MESCs_Mouse1.74403505
39SMAD4_21799915_ChIP-Seq_A2780_Human1.72773471
40GABP_17652178_ChIP-ChIP_JURKAT_Human1.72094042
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.71230350
42* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69580656
43RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68235909
44EWS_26573619_Chip-Seq_HEK293_Human1.67114079
45FUS_26573619_Chip-Seq_HEK293_Human1.65759258
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.57253761
47ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.54560431
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.53180020
49DROSHA_22980978_ChIP-Seq_HELA_Human1.52562487
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.52239518
51* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49253644
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48973199
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.48766084
54NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.47848690
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46885064
56ZNF274_21170338_ChIP-Seq_K562_Hela1.46088520
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.42469866
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.40868551
59EST1_17652178_ChIP-ChIP_JURKAT_Human1.40258791
60ELK1_19687146_ChIP-ChIP_HELA_Human1.40215009
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.38115748
62IRF1_19129219_ChIP-ChIP_H3396_Human1.38054968
63SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37746323
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.37079902
65REST_18959480_ChIP-ChIP_MESCs_Mouse1.34675531
66AR_25329375_ChIP-Seq_VCAP_Human1.33861979
67* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.33305630
68MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33045373
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33019340
70TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.31220998
71RING1B_27294783_Chip-Seq_ESCs_Mouse1.27668340
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24423470
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.24356809
74EP300_21415370_ChIP-Seq_HL-1_Mouse1.24348935
75TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24059784
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.24059784
77FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.23534339
78MYC_18940864_ChIP-ChIP_HL60_Human1.21114548
79* SOX2_21211035_ChIP-Seq_LN229_Gbm1.20767969
80BCAT_22108803_ChIP-Seq_LS180_Human1.16827582
81RNF2_27304074_Chip-Seq_NSC_Mouse1.16671548
82TP53_18474530_ChIP-ChIP_U2OS_Human1.16152901
83SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.15454555
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13828737
85TP53_20018659_ChIP-ChIP_R1E_Mouse1.12700055
86SALL1_21062744_ChIP-ChIP_HESCs_Human1.12299976
87TP53_22573176_ChIP-Seq_HFKS_Human1.11915096
88YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09715358
89ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09370185
90SMAD_19615063_ChIP-ChIP_OVARY_Human1.09111351
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.08392389
92PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08308198
93POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07482416
94ERG_21242973_ChIP-ChIP_JURKAT_Human1.07400014
95SOX2_16153702_ChIP-ChIP_HESCs_Human1.07175713
96EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06923688
97IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.06555653
98CBP_20019798_ChIP-Seq_JUKART_Human1.06555653
99UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05705419
100YY1_21170310_ChIP-Seq_MESCs_Mouse1.03734754
101NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03336936
102RARB_27405468_Chip-Seq_BRAIN_Mouse1.03307504
103CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03191375
104PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02963223
105TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02619657
106NANOG_18555785_Chip-Seq_ESCs_Mouse1.02289806
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01964477
108NANOG_19829295_ChIP-Seq_ESCs_Human1.01840270
109SOX2_19829295_ChIP-Seq_ESCs_Human1.01840270
110TAL1_26923725_Chip-Seq_HPCs_Mouse1.01779658
111HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01367324
112EZH2_27294783_Chip-Seq_NPCs_Mouse1.01318739
113RUNX2_22187159_ChIP-Seq_PCA_Human1.01189843
114* JUN_21703547_ChIP-Seq_K562_Human1.01054276
115TCF4_23295773_ChIP-Seq_U87_Human1.00640125
116* GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99062906
117SOX9_26525672_Chip-Seq_HEART_Mouse0.97979518
118TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97911843
119WT1_25993318_ChIP-Seq_PODOCYTE_Human0.97030059
120AR_19668381_ChIP-Seq_PC3_Human0.96933024
121SMAD4_21741376_ChIP-Seq_HESCs_Human0.96681564
122CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.96406591
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96184381
124SMAD4_21741376_ChIP-Seq_EPCs_Human0.95145249
125SMAD3_21741376_ChIP-Seq_ESCs_Human0.93165044
126IGF1R_20145208_ChIP-Seq_DFB_Human0.93149300
127NFE2_27457419_Chip-Seq_LIVER_Mouse0.92882146
128NRF2_20460467_ChIP-Seq_MEFs_Mouse0.92841446
129NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.92841446
130PRDM14_20953172_ChIP-Seq_ESCs_Human0.92541727
131* STAT3_23295773_ChIP-Seq_U87_Human0.91830820
132ER_23166858_ChIP-Seq_MCF-7_Human0.91808342
133EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.91672039
134CJUN_26792858_Chip-Seq_BT549_Human0.91499546
135CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91495471
136NANOG_16153702_ChIP-ChIP_HESCs_Human0.91305849
137RING1B_27294783_Chip-Seq_NPCs_Mouse0.90958138
138WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.89907714
139LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89839584
140TCF4_22108803_ChIP-Seq_LS180_Human0.87228529
141ARNT_22903824_ChIP-Seq_MCF-7_Human0.86392591
142AHR_22903824_ChIP-Seq_MCF-7_Human0.83575214
143RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83283861

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting3.62464548
2MP0001529_abnormal_vocalization3.34860524
3MP0002822_catalepsy3.00028167
4MP0006276_abnormal_autonomic_nervous2.83692370
5MP0005503_abnormal_tendon_morphology2.81493091
6MP0004858_abnormal_nervous_system2.69647728
7MP0000751_myopathy2.57973767
8MP0005645_abnormal_hypothalamus_physiol2.53355353
9MP0003635_abnormal_synaptic_transmissio2.31924507
10MP0006072_abnormal_retinal_apoptosis2.31022217
11MP0003646_muscle_fatigue2.26555578
12MP0002734_abnormal_mechanical_nocicepti2.23220985
13MP0004233_abnormal_muscle_weight2.22887560
14MP0004270_analgesia2.22393181
15MP0002184_abnormal_innervation2.10272883
16MP0009745_abnormal_behavioral_response2.03045089
17MP0001440_abnormal_grooming_behavior2.02723511
18MP0004145_abnormal_muscle_electrophysio2.00960321
19MP0002163_abnormal_gland_morphology1.98680515
20MP0008438_abnormal_cutaneous_collagen1.96991638
21MP0002272_abnormal_nervous_system1.95719942
22MP0001501_abnormal_sleep_pattern1.94560482
23MP0002064_seizures1.90880055
24MP0008789_abnormal_olfactory_epithelium1.90843369
25MP0005394_taste/olfaction_phenotype1.89085455
26MP0005499_abnormal_olfactory_system1.89085455
27MP0006292_abnormal_olfactory_placode1.88814542
28MP0004859_abnormal_synaptic_plasticity1.86721125
29MP0010386_abnormal_urinary_bladder1.86668590
30MP0002102_abnormal_ear_morphology1.83180772
31MP0002108_abnormal_muscle_morphology1.82258674
32MP0009046_muscle_twitch1.80562671
33MP0003890_abnormal_embryonic-extraembry1.75889193
34MP0001299_abnormal_eye_distance/1.71616140
35MP0002572_abnormal_emotion/affect_behav1.71408572
36MP0000955_abnormal_spinal_cord1.68901544
37MP0003941_abnormal_skin_development1.68399013
38MP0008877_abnormal_DNA_methylation1.65713857
39MP0003880_abnormal_central_pattern1.64099271
40MP0003942_abnormal_urinary_system1.62617736
41MP0004142_abnormal_muscle_tone1.59470885
42MP0009250_abnormal_appendicular_skeleto1.58677333
43MP0005257_abnormal_intraocular_pressure1.57460351
44MP0002063_abnormal_learning/memory/cond1.56834340
45MP0003045_fibrosis1.56444774
46MP0001970_abnormal_pain_threshold1.56126184
47MP0005253_abnormal_eye_physiology1.53781939
48MP0000372_irregular_coat_pigmentation1.49621247
49MP0003121_genomic_imprinting1.49378889
50MP0005623_abnormal_meninges_morphology1.48520756
51MP0004272_abnormal_basement_membrane1.46898624
52MP0000534_abnormal_ureter_morphology1.46856553
53MP0005275_abnormal_skin_tensile1.46846519
54MP0000747_muscle_weakness1.40832627
55MP0004924_abnormal_behavior1.40085579
56MP0005386_behavior/neurological_phenoty1.40085579
57MP0002735_abnormal_chemical_nociception1.38630496
58MP0003385_abnormal_body_wall1.35328260
59MP0000750_abnormal_muscle_regeneration1.34888423
60MP0001968_abnormal_touch/_nociception1.32178382
61MP0000538_abnormal_urinary_bladder1.31628023
62MP0005423_abnormal_somatic_nervous1.27679983
63MP0000631_abnormal_neuroendocrine_gland1.27250662
64MP0010030_abnormal_orbit_morphology1.26573689
65MP0005379_endocrine/exocrine_gland_phen1.25423545
66MP0002332_abnormal_exercise_endurance1.25230757
67MP0001188_hyperpigmentation1.22427253
68MP0002736_abnormal_nociception_after1.21563988
69MP0002638_abnormal_pupillary_reflex1.20932341
70MP0002752_abnormal_somatic_nervous1.20473451
71MP0002751_abnormal_autonomic_nervous1.18879394
72MP0004883_abnormal_blood_vessel1.17054086
73MP0001177_atelectasis1.16844614
74MP0003567_abnormal_fetal_cardiomyocyte1.16687621
75MP0002233_abnormal_nose_morphology1.15850818
76MP0002557_abnormal_social/conspecific_i1.15515443
77MP0003787_abnormal_imprinting1.15466395
78MP0001286_abnormal_eye_development1.14985362
79MP0008775_abnormal_heart_ventricle1.14170521
80MP0000759_abnormal_skeletal_muscle1.14133269
81MP0008872_abnormal_physiological_respon1.13711797
82MP0001293_anophthalmia1.13248001
83MP0004133_heterotaxia1.12974324
84MP0002733_abnormal_thermal_nociception1.10216923
85MP0005551_abnormal_eye_electrophysiolog1.09488498
86MP0002282_abnormal_trachea_morphology1.08831280
87MP0005248_abnormal_Harderian_gland1.08620775
88MP0002234_abnormal_pharynx_morphology1.08443420
89MP0004084_abnormal_cardiac_muscle1.08018161
90MP0000733_abnormal_muscle_development1.07043678
91MP0000778_abnormal_nervous_system1.06229033
92MP0004036_abnormal_muscle_relaxation1.06187258
93MP0002837_dystrophic_cardiac_calcinosis1.05659275
94MP0005197_abnormal_uvea_morphology1.01485628
95MP0001984_abnormal_olfaction1.01138245
96MP0002909_abnormal_adrenal_gland1.00818942
97MP0000749_muscle_degeneration1.00653204
98MP0002882_abnormal_neuron_morphology1.00153773
99MP0005391_vision/eye_phenotype0.99991814
100MP0000569_abnormal_digit_pigmentation0.99359811
101MP0008058_abnormal_DNA_repair0.98326850
102MP0005369_muscle_phenotype0.97887373
103MP0001943_abnormal_respiration0.97331158
104MP0008995_early_reproductive_senescence0.96132255
105MP0002067_abnormal_sensory_capabilities0.95313575
106MP0003136_yellow_coat_color0.94436012
107MP0000428_abnormal_craniofacial_morphol0.94302617
108MP0003119_abnormal_digestive_system0.93743386
109MP0003755_abnormal_palate_morphology0.93705381
110MP0004811_abnormal_neuron_physiology0.93482805
111MP0005187_abnormal_penis_morphology0.92557841
112MP0000026_abnormal_inner_ear0.91543340
113MP0003861_abnormal_nervous_system0.91033986
114MP0001905_abnormal_dopamine_level0.90312038
115MP0002269_muscular_atrophy0.90023751
116MP0003937_abnormal_limbs/digits/tail_de0.89924318
117MP0003938_abnormal_ear_development0.87702466
118MP0002938_white_spotting0.87138099
119MP0003879_abnormal_hair_cell0.86687867
120MP0001486_abnormal_startle_reflex0.86071260
121MP0000049_abnormal_middle_ear0.85086348
122MP0003279_aneurysm0.84702756
123MP0001485_abnormal_pinna_reflex0.84126690
124MP0003693_abnormal_embryo_hatching0.83151495
125MP0002106_abnormal_muscle_physiology0.82354076
126MP0000566_synostosis0.82289131
127MP0002168_other_aberrant_phenotype0.81724688
128MP0004484_altered_response_of0.81562505
129MP0006138_congestive_heart_failure0.81259675
130MP0005195_abnormal_posterior_eye0.81191623
131MP0001270_distended_abdomen0.80997343
132MP0003123_paternal_imprinting0.80690115
133MP0001986_abnormal_taste_sensitivity0.80294382
134MP0000516_abnormal_urinary_system0.79946683
135MP0005367_renal/urinary_system_phenotyp0.79946683
136MP0005620_abnormal_muscle_contractility0.77476392
137MP0004087_abnormal_muscle_fiber0.77230032
138MP0005646_abnormal_pituitary_gland0.77095239
139MP0009379_abnormal_foot_pigmentation0.76817642
140MP0002932_abnormal_joint_morphology0.74898418
141MP0000013_abnormal_adipose_tissue0.74746862
142MP0002066_abnormal_motor_capabilities/c0.74677838

Predicted human phenotypes

RankGene SetZ-score
1Distal arthrogryposis (HP:0005684)7.73742321
2Hypothermia (HP:0002045)4.72222548
3Calcaneovalgus deformity (HP:0001848)4.65908192
4Round ear (HP:0100830)4.36332551
5Deformed tarsal bones (HP:0008119)4.10567887
6Ulnar deviation of the wrist (HP:0003049)3.87386703
7Fetal akinesia sequence (HP:0001989)3.61178140
8Distal lower limb amyotrophy (HP:0008944)3.54879197
9Hypoventilation (HP:0002791)3.54732480
10Myokymia (HP:0002411)3.52883295
11Absent phalangeal crease (HP:0006109)3.46817684
12Broad metatarsal (HP:0001783)3.43697662
13Abnormal hair whorl (HP:0010721)3.41079537
14Popliteal pterygium (HP:0009756)3.36906981
15Abnormality of the labia minora (HP:0012880)3.36603736
16Abnormality of the calf musculature (HP:0001430)3.26556436
17Pheochromocytoma (HP:0002666)3.18223180
18Pancreatic fibrosis (HP:0100732)3.11358108
19Lower limb amyotrophy (HP:0007210)3.09838584
20Atonic seizures (HP:0010819)3.08637043
21Midline defect of the nose (HP:0004122)3.07570577
22Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.01737586
23Narrow nasal bridge (HP:0000446)2.94171900
24Abnormal finger flexion creases (HP:0006143)2.93611893
25Neuroendocrine neoplasm (HP:0100634)2.89721554
26Premature rupture of membranes (HP:0001788)2.87740715
27Chin dimple (HP:0010751)2.84745233
28Muscle fiber inclusion bodies (HP:0100299)2.82518016
29Polyphagia (HP:0002591)2.76645732
30Abnormality of placental membranes (HP:0011409)2.71809910
31Amniotic constriction ring (HP:0009775)2.71809910
32Focal seizures (HP:0007359)2.69288155
33Myotonia (HP:0002486)2.68629072
34Shallow orbits (HP:0000586)2.66860048
35Pancreatic cysts (HP:0001737)2.66844543
36Trismus (HP:0000211)2.66261128
37Abnormality of the calcaneus (HP:0008364)2.66232820
38Protrusio acetabuli (HP:0003179)2.64288429
39Oligodactyly (hands) (HP:0001180)2.63264574
40Supernumerary spleens (HP:0009799)2.61674069
41Short tibia (HP:0005736)2.60204556
42Difficulty climbing stairs (HP:0003551)2.59582969
43Abnormal respiratory motile cilium morphology (HP:0005938)2.56837423
44Abnormal respiratory epithelium morphology (HP:0012253)2.56837423
45Wrist flexion contracture (HP:0001239)2.56782513
46Short 4th metacarpal (HP:0010044)2.55257771
47Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.55257771
48Aplasia/Hypoplasia of the tibia (HP:0005772)2.54059457
49Failure to thrive in infancy (HP:0001531)2.53959593
50Infantile muscular hypotonia (HP:0008947)2.53479775
51Absence seizures (HP:0002121)2.51080893
52Poor suck (HP:0002033)2.48263675
53Aplasia involving bones of the extremities (HP:0009825)2.46423696
54Aplasia involving bones of the upper limbs (HP:0009823)2.46423696
55Aplasia of the phalanges of the hand (HP:0009802)2.46423696
56Humeroradial synostosis (HP:0003041)2.45629288
57Synostosis involving the elbow (HP:0003938)2.45629288
58Mildly elevated creatine phosphokinase (HP:0008180)2.44806357
59Malignant hyperthermia (HP:0002047)2.44394841
60Genital tract atresia (HP:0001827)2.40911972
61Type 1 muscle fiber predominance (HP:0003803)2.39507390
62Exercise-induced muscle cramps (HP:0003710)2.38632377
63Aplasia/Hypoplasia of the tongue (HP:0010295)2.37827234
64Oligomenorrhea (HP:0000876)2.37088218
65Abnormality of the nasal septum (HP:0000419)2.35718252
66Shoulder girdle muscle weakness (HP:0003547)2.34332188
67Cutaneous syndactyly (HP:0012725)2.34135017
68Symphalangism affecting the phalanges of the hand (HP:0009773)2.33839122
69Muscle fiber splitting (HP:0003555)2.32264067
70Asymmetry of the thorax (HP:0001555)2.31919473
71Breech presentation (HP:0001623)2.30851353
72Medial flaring of the eyebrow (HP:0010747)2.28502098
73Abnormality of the parietal bone (HP:0002696)2.27858836
74Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.27312465
75True hermaphroditism (HP:0010459)2.25579829
76Microglossia (HP:0000171)2.25278995
77Nephronophthisis (HP:0000090)2.24709057
78Abnormal respiratory motile cilium physiology (HP:0012261)2.24650927
79Muscle hypertrophy of the lower extremities (HP:0008968)2.23835640
80Gait imbalance (HP:0002141)2.23631796
81Metatarsus adductus (HP:0001840)2.23357966
82Generalized tonic-clonic seizures (HP:0002069)2.18824095
83Febrile seizures (HP:0002373)2.18038551
84Abnormality of the corticospinal tract (HP:0002492)2.17580653
85Abnormality of midbrain morphology (HP:0002418)2.17513622
86Molar tooth sign on MRI (HP:0002419)2.17513622
87Exotropia (HP:0000577)2.17047262
88Decreased muscle mass (HP:0003199)2.16791187
89Turricephaly (HP:0000262)2.16381854
90Progressive cerebellar ataxia (HP:0002073)2.12172306
91Abnormal ciliary motility (HP:0012262)2.11818780
92Absent septum pellucidum (HP:0001331)2.11405655
93Increased connective tissue (HP:0009025)2.10976417
94Abnormality of the septum pellucidum (HP:0007375)2.10935821
95Calf muscle hypertrophy (HP:0008981)2.08529693
96Abnormality of the hip-girdle musculature (HP:0001445)2.08233320
97Abnormality of the musculature of the pelvis (HP:0001469)2.08233320
98Anterior segment dysgenesis (HP:0007700)2.07725738
99Congenital primary aphakia (HP:0007707)2.06703412
100Anteriorly placed anus (HP:0001545)2.06681413
101Impaired pain sensation (HP:0007328)2.04636465
102Abnormality of pain sensation (HP:0010832)2.04636465
103Aplasia/Hypoplasia involving the musculature (HP:0001460)2.04276560
104Focal motor seizures (HP:0011153)2.04181479
105Abnormality of the 4th metacarpal (HP:0010012)2.02814207
106Orthostatic hypotension (HP:0001278)2.01617171
107Spinal rigidity (HP:0003306)2.01356278
108Abnormality of dentin (HP:0010299)1.99996771
109Nasolacrimal duct obstruction (HP:0000579)1.99832418
110Abnormality of the nasolacrimal system (HP:0000614)1.98481032
111Hip contracture (HP:0003273)1.97832239
112Ankle contracture (HP:0006466)1.97584128
113Vaginal atresia (HP:0000148)1.97530732
114Limb-girdle muscle weakness (HP:0003325)1.97521048
115Sleep apnea (HP:0010535)1.97318384
116Pachygyria (HP:0001302)1.96542799
117Buphthalmos (HP:0000557)1.95686058
118Nephrogenic diabetes insipidus (HP:0009806)1.95556792
119Rhinitis (HP:0012384)1.95485810
120Neoplasm of the heart (HP:0100544)1.94507795
121Postaxial foot polydactyly (HP:0001830)1.94476289
122Anencephaly (HP:0002323)1.94252739
123Nasal speech (HP:0001611)1.94150664
124Agitation (HP:0000713)1.93980895
125Fragile skin (HP:0001030)1.92988810
126Trigonocephaly (HP:0000243)1.92731781
127Aplasia of the musculature (HP:0100854)1.92127872
128Bell-shaped thorax (HP:0001591)1.91301835
129Aplasia/Hypoplasia of the brainstem (HP:0007362)1.90537595
130Hypoplasia of the brainstem (HP:0002365)1.90537595
131Pelvic girdle muscle weakness (HP:0003749)1.90409750
132Cortical dysplasia (HP:0002539)1.88319668
133Septo-optic dysplasia (HP:0100842)1.87292608
134Visual hallucinations (HP:0002367)1.86750654
135Bronchomalacia (HP:0002780)1.86103241
136Abnormality of the vocal cords (HP:0008777)1.85476095
137Oligodactyly (HP:0012165)1.85052434
138Amblyopia (HP:0000646)1.84675270
139Overgrowth (HP:0001548)1.84450265
140Narrow forehead (HP:0000341)1.84247972
141Dialeptic seizures (HP:0011146)1.83291654
142Type 2 muscle fiber atrophy (HP:0003554)1.82674362
143Neoplasm of the peripheral nervous system (HP:0100007)1.81723964
144Abnormality of the neuromuscular junction (HP:0003398)1.80666434
145Fatigable weakness (HP:0003473)1.80666434
146Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80544675
147Degeneration of the lateral corticospinal tracts (HP:0002314)1.80544675
148Anxiety (HP:0000739)1.79676419
149Reticulocytopenia (HP:0001896)1.78876737
150Nemaline bodies (HP:0003798)1.77799599
151Limb-girdle muscle atrophy (HP:0003797)1.76786768
152Wide anterior fontanel (HP:0000260)1.76406345
153Abnormal autonomic nervous system physiology (HP:0012332)1.75303757
154Acute necrotizing encephalopathy (HP:0006965)1.74733217
155Aqueductal stenosis (HP:0002410)1.74252330
156Abnormal auditory evoked potentials (HP:0006958)1.73991308
157Abnormality of the lacrimal duct (HP:0011481)1.73870528
158Abnormality of the labia (HP:0000058)1.73557591
159Generalized hypotonia (HP:0001290)1.71565989
160Keratoconus (HP:0000563)1.70903243
161Increased corneal curvature (HP:0100692)1.70903243
162EMG: myopathic abnormalities (HP:0003458)1.70427449
163Limb dystonia (HP:0002451)1.70276435
164Rimmed vacuoles (HP:0003805)1.69611519
165Cystic liver disease (HP:0006706)1.68632122
166Growth hormone deficiency (HP:0000824)1.68604633
167Lissencephaly (HP:0001339)1.68371980
168Abnormality of the renal medulla (HP:0100957)1.67799413
169Median cleft lip (HP:0000161)1.67695816
170Retinal dysplasia (HP:0007973)1.66404832
171Osteomalacia (HP:0002749)1.66316508
172Cystic hygroma (HP:0000476)1.66176220
173Tubulointerstitial nephritis (HP:0001970)1.62278315
174Concave nail (HP:0001598)1.62088215
175Acute encephalopathy (HP:0006846)1.61627676
176Rib fusion (HP:0000902)1.60718763
177Postaxial hand polydactyly (HP:0001162)1.60472374
178Limited hip movement (HP:0008800)1.59565964

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.31086207
2MAP3K123.85701533
3MAP4K23.78355274
4GRK73.72503838
5MUSK3.67197204
6CASK3.41885904
7MAP3K43.39753249
8MAP2K72.85881757
9TNIK2.74400513
10MINK12.59992432
11EPHA32.52252819
12TRIM282.51940353
13PIM22.42467115
14SRPK12.27625537
15MAP2K42.23168675
16DYRK1B2.12784152
17BCR2.00169447
18ZAK1.90880884
19FGFR41.86856791
20MAPK131.83553944
21DDR21.81364797
22NTRK11.78751028
23NTRK21.70490581
24NTRK31.69479752
25UHMK11.43726586
26GRK51.43426003
27STK38L1.42890714
28NME11.38296977
29CAMK41.37040838
30GRK11.34092742
31ADRBK11.33353145
32BMPR1B1.30656430
33LATS21.29833184
34NUAK11.27044395
35OBSCN1.26813976
36PINK11.18558841
37PRKCE1.17323661
38PHKG21.16357420
39PHKG11.16357420
40PLK41.15638535
41SGK2231.10482803
42SGK4941.10482803
43CDC71.08705837
44CAMK2A1.06211036
45LIMK11.06107978
46SIK31.05960376
47CAMK11.04225934
48PLK21.03326012
49PRPF4B1.01802363
50PAK31.01722783
51TTN1.00538149
52AKT31.00240077
53MYLK0.99208581
54DYRK20.99171821
55VRK10.99030877
56TSSK60.96305318
57DYRK30.96196999
58STK160.95499289
59PAK60.93304282
60INSRR0.93094876
61IRAK10.93025221
62CSNK1G10.92986122
63EPHA40.92360439
64BRSK20.91509731
65BCKDK0.90127003
66PNCK0.89731490
67DAPK20.89635765
68FER0.88082677
69WEE10.87912171
70MAP3K50.87650788
71SIK20.86965975
72CCNB10.86313296
73CDK50.84656377
74MAP2K10.82597236
75MARK20.82492695
76CAMK2B0.81777232
77CAMK2G0.81128388
78CAMK2D0.80860524
79RPS6KC10.80434785
80RPS6KL10.80434785
81PRKCG0.80394770
82ADRBK20.79838268
83ERBB40.78081284
84MOS0.77387678
85ROCK10.76691035
86BRSK10.74954990
87KSR10.73774076
88TAOK20.73614788
89FGFR20.72524211
90ROCK20.69794303
91PLK10.66838615
92LATS10.66823330
93PBK0.65980695
94MKNK10.64082821
95MKNK20.63905263
96PLK30.63117987
97RPS6KA60.62100799
98SGK20.61604492
99CDK140.59652554
100PRKCH0.58390669
101CSNK1G30.58030647
102PIK3CG0.57686188
103EIF2AK30.57258320
104FGFR10.57220346
105WNK10.57078287
106RPS6KA20.56477870
107CAMKK20.56249411
108CDK180.56126440
109CDK150.55819938
110TIE10.55556088
111CDK70.54452510
112LMTK20.54119379
113ICK0.54107979
114PKN10.53869402
115MAP3K60.53711994
116CSNK1G20.53451338
117ALK0.53024887
118EPHB20.52744405
119PRKD30.52346156
120BMX0.51888700
121MAPK40.51785545
122DAPK10.51357901
123DYRK1A0.51260754
124PIK3CA0.49823875
125RET0.49790976
126IRAK20.47741778
127FRK0.47647710
128STK30.47472726
129CDK190.47438907
130ACVR1B0.46787071
131MAP3K90.45871199
132ERBB30.45631517
133MAPK80.45474105
134WNK40.44879726
135AURKA0.44811948
136OXSR10.44149446
137MAPKAPK50.43268450
138ERBB20.42927189
139SGK30.42728461
140CDK11A0.42455609
141CSNK1A1L0.42291249
142TGFBR10.41868947
143DAPK30.40183520
144WNK30.38125256
145PRKG10.37423302
146PRKACA0.36967896
147CSNK1E0.36286895
148PASK0.35565815
149AKT20.35484184
150STK380.34842748
151TTK0.33857551

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.16934255
2Nicotine addiction_Homo sapiens_hsa050332.94059837
3Protein export_Homo sapiens_hsa030602.89441590
4Oxidative phosphorylation_Homo sapiens_hsa001902.79141950
5Parkinsons disease_Homo sapiens_hsa050122.28965513
6Collecting duct acid secretion_Homo sapiens_hsa049662.27529686
7GABAergic synapse_Homo sapiens_hsa047272.23888318
8Cholinergic synapse_Homo sapiens_hsa047252.21072130
9RNA polymerase_Homo sapiens_hsa030202.11136716
10Alzheimers disease_Homo sapiens_hsa050102.04787439
11Circadian entrainment_Homo sapiens_hsa047132.04607805
12Olfactory transduction_Homo sapiens_hsa047402.00978127
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.99528994
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.97329029
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.95393841
16Vibrio cholerae infection_Homo sapiens_hsa051101.90623398
17Morphine addiction_Homo sapiens_hsa050321.89165382
18Renin-angiotensin system_Homo sapiens_hsa046141.82756476
19Long-term depression_Homo sapiens_hsa047301.81943495
20Steroid biosynthesis_Homo sapiens_hsa001001.74157279
21Ribosome_Homo sapiens_hsa030101.74120125
22Amphetamine addiction_Homo sapiens_hsa050311.73300505
23Taste transduction_Homo sapiens_hsa047421.72342547
24Cocaine addiction_Homo sapiens_hsa050301.71848428
25Propanoate metabolism_Homo sapiens_hsa006401.66563469
26Dopaminergic synapse_Homo sapiens_hsa047281.64394200
27Serotonergic synapse_Homo sapiens_hsa047261.63119477
28Basal transcription factors_Homo sapiens_hsa030221.63000461
29Renin secretion_Homo sapiens_hsa049241.60323989
30Salivary secretion_Homo sapiens_hsa049701.59952866
31Dilated cardiomyopathy_Homo sapiens_hsa054141.55717345
32Cardiac muscle contraction_Homo sapiens_hsa042601.52904751
33Fanconi anemia pathway_Homo sapiens_hsa034601.52762445
34Gap junction_Homo sapiens_hsa045401.51404733
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.49205783
36Proteasome_Homo sapiens_hsa030501.48291720
37Huntingtons disease_Homo sapiens_hsa050161.47336891
38Glutamatergic synapse_Homo sapiens_hsa047241.43301101
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.35973189
40RNA degradation_Homo sapiens_hsa030181.34733316
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.34292620
42Axon guidance_Homo sapiens_hsa043601.34103607
43Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.33828281
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.32215319
45Calcium signaling pathway_Homo sapiens_hsa040201.31395756
46Long-term potentiation_Homo sapiens_hsa047201.31357560
47Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.30441107
48Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.29636333
49Oxytocin signaling pathway_Homo sapiens_hsa049211.25542197
50Insulin secretion_Homo sapiens_hsa049111.24736119
51Mismatch repair_Homo sapiens_hsa034301.24376335
52Regulation of autophagy_Homo sapiens_hsa041401.22848883
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22533909
54GnRH signaling pathway_Homo sapiens_hsa049121.20125274
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19464772
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.18478606
57Hedgehog signaling pathway_Homo sapiens_hsa043401.15817992
58Aldosterone synthesis and secretion_Homo sapiens_hsa049251.14680588
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.13243374
60Phagosome_Homo sapiens_hsa041451.12856338
61ECM-receptor interaction_Homo sapiens_hsa045121.12810650
62Base excision repair_Homo sapiens_hsa034101.12141072
63Oocyte meiosis_Homo sapiens_hsa041141.08948011
64Gastric acid secretion_Homo sapiens_hsa049711.07501308
65Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99788808
66Fatty acid elongation_Homo sapiens_hsa000620.99089200
67Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.98438709
68Tryptophan metabolism_Homo sapiens_hsa003800.91476194
69Homologous recombination_Homo sapiens_hsa034400.89122550
70cAMP signaling pathway_Homo sapiens_hsa040240.88279193
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87443464
72DNA replication_Homo sapiens_hsa030300.87390933
73Butanoate metabolism_Homo sapiens_hsa006500.87118468
74Prion diseases_Homo sapiens_hsa050200.85408972
75Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.84868141
76Melanogenesis_Homo sapiens_hsa049160.83906230
77Tyrosine metabolism_Homo sapiens_hsa003500.83884068
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.83748784
79Arginine biosynthesis_Homo sapiens_hsa002200.83194515
80Tight junction_Homo sapiens_hsa045300.82814761
81p53 signaling pathway_Homo sapiens_hsa041150.82615686
82Non-homologous end-joining_Homo sapiens_hsa034500.81056972
83Phenylalanine metabolism_Homo sapiens_hsa003600.80988838
84Wnt signaling pathway_Homo sapiens_hsa043100.80920749
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.80907666
86Alcoholism_Homo sapiens_hsa050340.80643136
87Linoleic acid metabolism_Homo sapiens_hsa005910.79307695
88Vascular smooth muscle contraction_Homo sapiens_hsa042700.79038897
89MAPK signaling pathway_Homo sapiens_hsa040100.78682221
90Maturity onset diabetes of the young_Homo sapiens_hsa049500.77795495
91Melanoma_Homo sapiens_hsa052180.76510253
92Estrogen signaling pathway_Homo sapiens_hsa049150.75486793
93Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.75345374
94beta-Alanine metabolism_Homo sapiens_hsa004100.74618797
95Basal cell carcinoma_Homo sapiens_hsa052170.74507433
96ErbB signaling pathway_Homo sapiens_hsa040120.74452268
97Purine metabolism_Homo sapiens_hsa002300.72977731
98Sulfur metabolism_Homo sapiens_hsa009200.72537708
99Type II diabetes mellitus_Homo sapiens_hsa049300.71561565
100Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71552655
101Dorso-ventral axis formation_Homo sapiens_hsa043200.70136906
102Pyruvate metabolism_Homo sapiens_hsa006200.70045546
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69230695
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.67357548
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.64308286
106Ovarian steroidogenesis_Homo sapiens_hsa049130.64141895
107RNA transport_Homo sapiens_hsa030130.63983430
108Pyrimidine metabolism_Homo sapiens_hsa002400.63884103
109Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63425723
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62955627
111Cell cycle_Homo sapiens_hsa041100.62835263
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.62407823
113Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61100738
114Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60803901
115Focal adhesion_Homo sapiens_hsa045100.60738290
116Rheumatoid arthritis_Homo sapiens_hsa053230.59953125
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.57604857
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57449805
119Ras signaling pathway_Homo sapiens_hsa040140.55756659
120Glioma_Homo sapiens_hsa052140.54737069
121Colorectal cancer_Homo sapiens_hsa052100.54649335
122Choline metabolism in cancer_Homo sapiens_hsa052310.54360153
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53729662
124Thyroid hormone synthesis_Homo sapiens_hsa049180.52807420
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.52359645
126Ether lipid metabolism_Homo sapiens_hsa005650.51182762
127Circadian rhythm_Homo sapiens_hsa047100.49182272
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49099837
129Metabolic pathways_Homo sapiens_hsa011000.48741712
130Nucleotide excision repair_Homo sapiens_hsa034200.48106810
131Protein digestion and absorption_Homo sapiens_hsa049740.48017588
132Vitamin B6 metabolism_Homo sapiens_hsa007500.47923743
133Amoebiasis_Homo sapiens_hsa051460.47599004
134Rap1 signaling pathway_Homo sapiens_hsa040150.47515673
135Glucagon signaling pathway_Homo sapiens_hsa049220.46657272
136Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43834450
137Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41474341
138PI3K-Akt signaling pathway_Homo sapiens_hsa041510.41405359
139Phospholipase D signaling pathway_Homo sapiens_hsa040720.38926088
140Arginine and proline metabolism_Homo sapiens_hsa003300.38825904
141Neurotrophin signaling pathway_Homo sapiens_hsa047220.38407862
142Hippo signaling pathway_Homo sapiens_hsa043900.38348556
143Insulin signaling pathway_Homo sapiens_hsa049100.37617737
144Phototransduction_Homo sapiens_hsa047440.37258112
145Proteoglycans in cancer_Homo sapiens_hsa052050.36555390
146Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36040074
147Regulation of actin cytoskeleton_Homo sapiens_hsa048100.33474617
148Pathways in cancer_Homo sapiens_hsa052000.33098926
149Renal cell carcinoma_Homo sapiens_hsa052110.33038352
150African trypanosomiasis_Homo sapiens_hsa051430.32921949
151Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32874345

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