Rank | Gene Set | Z-score |
---|---|---|
1 | hemidesmosome assembly (GO:0031581) | 4.84305704 |
2 | basement membrane organization (GO:0071711) | 4.43476027 |
3 | COPI coating of Golgi vesicle (GO:0048205) | 4.19636530 |
4 | Golgi transport vesicle coating (GO:0048200) | 4.19636530 |
5 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.91413961 |
6 | synaptic vesicle maturation (GO:0016188) | 3.87371754 |
7 | desmosome organization (GO:0002934) | 3.85057893 |
8 | protein heterotrimerization (GO:0070208) | 3.84205270 |
9 | protein retention in ER lumen (GO:0006621) | 3.81926502 |
10 | cell-substrate junction assembly (GO:0007044) | 3.78714318 |
11 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.76691775 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.72602257 |
13 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.68575094 |
14 | locomotory exploration behavior (GO:0035641) | 3.65056025 |
15 | regulation of extracellular matrix disassembly (GO:0010715) | 3.52883158 |
16 | cerebellar Purkinje cell layer development (GO:0021680) | 3.45976309 |
17 | collagen fibril organization (GO:0030199) | 3.43624501 |
18 | plasma membrane repair (GO:0001778) | 3.39659206 |
19 | proline biosynthetic process (GO:0006561) | 3.37612849 |
20 | adherens junction assembly (GO:0034333) | 3.35401964 |
21 | layer formation in cerebral cortex (GO:0021819) | 3.34390427 |
22 | semaphorin-plexin signaling pathway (GO:0071526) | 3.28756776 |
23 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.27235994 |
24 | cell-substrate adherens junction assembly (GO:0007045) | 3.22064091 |
25 | focal adhesion assembly (GO:0048041) | 3.22064091 |
26 | cell communication by electrical coupling (GO:0010644) | 3.21682328 |
27 | protein carboxylation (GO:0018214) | 3.21446228 |
28 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.21446228 |
29 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.20683343 |
30 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.20457099 |
31 | glomerular basement membrane development (GO:0032836) | 3.14060582 |
32 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.12820116 |
33 | cell adhesion mediated by integrin (GO:0033627) | 3.12685105 |
34 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.06126091 |
35 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.05714905 |
36 | sodium ion export (GO:0071436) | 3.01060863 |
37 | vocalization behavior (GO:0071625) | 3.00911437 |
38 | glutamate secretion (GO:0014047) | 2.99711720 |
39 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.98888745 |
40 | negative regulation of fatty acid transport (GO:2000192) | 2.98672711 |
41 | bone trabecula formation (GO:0060346) | 2.96762315 |
42 | chondrocyte proliferation (GO:0035988) | 2.96642977 |
43 | endothelial cell morphogenesis (GO:0001886) | 2.96496922 |
44 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.95957041 |
45 | activation of protein kinase A activity (GO:0034199) | 2.95692863 |
46 | synaptic vesicle exocytosis (GO:0016079) | 2.94964116 |
47 | atrioventricular valve morphogenesis (GO:0003181) | 2.92997885 |
48 | stress fiber assembly (GO:0043149) | 2.92766010 |
49 | proline transport (GO:0015824) | 2.92651503 |
50 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.89654600 |
51 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.89298535 |
52 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.89121455 |
53 | positive regulation of fibroblast migration (GO:0010763) | 2.88352517 |
54 | adhesion of symbiont to host (GO:0044406) | 2.87785227 |
55 | establishment of apical/basal cell polarity (GO:0035089) | 2.84546504 |
56 | extracellular matrix disassembly (GO:0022617) | 2.84114286 |
57 | cell-cell junction maintenance (GO:0045217) | 2.82966971 |
58 | regulation of synapse structural plasticity (GO:0051823) | 2.81494437 |
59 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.81451740 |
60 | regulation of plasminogen activation (GO:0010755) | 2.78577219 |
61 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.77241071 |
62 | axon extension involved in axon guidance (GO:0048846) | 2.77241071 |
63 | innervation (GO:0060384) | 2.76640103 |
64 | proline metabolic process (GO:0006560) | 2.76529802 |
65 | peptidyl-proline hydroxylation (GO:0019511) | 2.76510781 |
66 | dermatan sulfate biosynthetic process (GO:0030208) | 2.76409947 |
67 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.76393532 |
68 | regulation of cholesterol homeostasis (GO:2000188) | 2.75955399 |
69 | positive regulation of axon extension (GO:0045773) | 2.74472961 |
70 | positive regulation of nuclease activity (GO:0032075) | 2.74393815 |
71 | 4-hydroxyproline metabolic process (GO:0019471) | 2.74038353 |
72 | regulation of establishment of planar polarity (GO:0090175) | 2.73573372 |
73 | growth hormone secretion (GO:0030252) | 2.72437270 |
74 | negative regulation of catenin import into nucleus (GO:0035414) | 2.71382891 |
75 | dendritic spine morphogenesis (GO:0060997) | 2.71218896 |
76 | protein localization to endosome (GO:0036010) | 2.70960637 |
77 | exploration behavior (GO:0035640) | 2.70651877 |
78 | endothelial cell chemotaxis (GO:0035767) | 2.70235756 |
79 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.69011579 |
80 | positive regulation of osteoblast proliferation (GO:0033690) | 2.66915586 |
81 | barbed-end actin filament capping (GO:0051016) | 2.66458692 |
82 | establishment of nucleus localization (GO:0040023) | 2.62234573 |
83 | cochlea morphogenesis (GO:0090103) | 2.61524694 |
84 | convergent extension (GO:0060026) | 2.61211266 |
85 | multicellular organismal catabolic process (GO:0044243) | 2.60533643 |
86 | type B pancreatic cell proliferation (GO:0044342) | 2.60510795 |
87 | protein targeting to plasma membrane (GO:0072661) | 2.60194483 |
88 | lung epithelium development (GO:0060428) | 2.59782389 |
89 | multicellular organismal metabolic process (GO:0044236) | 2.59157671 |
90 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.57324024 |
91 | endocardial cushion development (GO:0003197) | 2.54686139 |
92 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.54656743 |
93 | positive regulation of synapse maturation (GO:0090129) | 2.54508329 |
94 | protein hydroxylation (GO:0018126) | 2.53367857 |
95 | regulation of early endosome to late endosome transport (GO:2000641) | 2.52617271 |
96 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.52327698 |
97 | regulation of synaptic vesicle transport (GO:1902803) | 2.51536456 |
98 | axonal fasciculation (GO:0007413) | 2.51299910 |
99 | virion attachment to host cell (GO:0019062) | 2.51275168 |
100 | adhesion of symbiont to host cell (GO:0044650) | 2.51275168 |
101 | L-serine transport (GO:0015825) | 2.50657386 |
102 | endodermal cell differentiation (GO:0035987) | 2.50463391 |
103 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.50173883 |
104 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.49134504 |
105 | activation of Rac GTPase activity (GO:0032863) | 2.48447099 |
106 | extracellular fibril organization (GO:0043206) | 2.48281816 |
107 | extracellular matrix assembly (GO:0085029) | 2.48132891 |
108 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.46222542 |
109 | polarized epithelial cell differentiation (GO:0030859) | 2.45902044 |
110 | cellular potassium ion homeostasis (GO:0030007) | 2.45844511 |
111 | regulation of cardioblast differentiation (GO:0051890) | 2.45837839 |
112 | tooth mineralization (GO:0034505) | 2.45812133 |
113 | inner ear receptor cell development (GO:0060119) | 2.45776217 |
114 | regulation of extracellular matrix organization (GO:1903053) | 2.45500241 |
115 | apoptotic process involved in morphogenesis (GO:0060561) | 2.45371416 |
116 | extracellular matrix organization (GO:0030198) | 2.44732991 |
117 | vesicle coating (GO:0006901) | 2.44609170 |
118 | dermatan sulfate metabolic process (GO:0030205) | 2.44323928 |
119 | axon extension (GO:0048675) | 2.44267969 |
120 | extracellular structure organization (GO:0043062) | 2.43640434 |
121 | positive regulation of vesicle fusion (GO:0031340) | 2.43575663 |
122 | neurotransmitter secretion (GO:0007269) | 2.43436788 |
123 | dendrite morphogenesis (GO:0048813) | 2.43436300 |
124 | embryo implantation (GO:0007566) | 2.43106841 |
125 | regulation of nuclease activity (GO:0032069) | 2.42344488 |
126 | skin morphogenesis (GO:0043589) | 2.41924348 |
127 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.41529778 |
128 | cell migration involved in heart development (GO:0060973) | 2.40501769 |
129 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.39595031 |
130 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.37731569 |
131 | regulation of apoptotic cell clearance (GO:2000425) | 2.37422087 |
132 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.36586266 |
133 | negative regulation of cartilage development (GO:0061037) | 2.36010752 |
134 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.35392796 |
135 | muscle cell migration (GO:0014812) | 2.35343927 |
136 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.35013861 |
137 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.33387005 |
138 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.33383854 |
139 | heparan sulfate proteoglycan metabolic process (GO:0030201) | 2.33088438 |
140 | mesodermal cell differentiation (GO:0048333) | 2.32776475 |
141 | gap junction assembly (GO:0016264) | 2.31457004 |
142 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.31255856 |
143 | glucose 6-phosphate metabolic process (GO:0051156) | 2.31103064 |
144 | neuromuscular process controlling balance (GO:0050885) | 2.30966785 |
145 | neuron recognition (GO:0008038) | 2.30944777 |
146 | protein maturation by protein folding (GO:0022417) | 2.30479500 |
147 | negative regulation of cell size (GO:0045792) | 2.29336136 |
148 | non-canonical Wnt signaling pathway (GO:0035567) | 2.29226663 |
149 | cellular response to unfolded protein (GO:0034620) | 2.27801304 |
150 | chondrocyte development (GO:0002063) | 2.27753361 |
151 | dendritic spine organization (GO:0097061) | 2.27406028 |
152 | collagen metabolic process (GO:0032963) | 2.27276110 |
153 | collagen catabolic process (GO:0030574) | 2.25496229 |
154 | protein localization to synapse (GO:0035418) | 2.22895324 |
155 | response to pheromone (GO:0019236) | 2.22581212 |
156 | apoptotic cell clearance (GO:0043277) | 2.20463378 |
157 | anatomical structure maturation (GO:0071695) | 2.19248487 |
158 | chondroitin sulfate catabolic process (GO:0030207) | 2.18548452 |
159 | ER-nucleus signaling pathway (GO:0006984) | 2.18389576 |
160 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.17693703 |
161 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.17011072 |
162 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.16938323 |
163 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.16475942 |
164 | epithelial cell-cell adhesion (GO:0090136) | 2.15888357 |
165 | neuron projection extension (GO:1990138) | 2.15660872 |
166 | cell migration in hindbrain (GO:0021535) | 2.15166268 |
167 | positive regulation of nitric-oxide synthase activity (GO:0051000) | 2.14681792 |
168 | alanine transport (GO:0032328) | 2.13756934 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.69070329 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.36545789 |
3 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.54920425 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.51601162 |
5 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.47757657 |
6 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.47757657 |
7 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.47132196 |
8 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.34237929 |
9 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.33889231 |
10 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.24177197 |
11 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.23233305 |
12 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.22342201 |
13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.21045700 |
14 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.17898601 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.13411907 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.13409387 |
17 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.11672987 |
18 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.10610240 |
19 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.10464573 |
20 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.09970216 |
21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.06133794 |
22 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.05052572 |
23 | KDM2B_26808549_Chip-Seq_K562_Human | 1.98453943 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.97713028 |
25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.92976305 |
26 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.90441488 |
27 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.83440967 |
28 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.78296530 |
29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.77440588 |
30 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.74679520 |
31 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.74023637 |
32 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.68646113 |
33 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.68362986 |
34 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.65894669 |
35 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.64771032 |
36 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.63793994 |
37 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.61876022 |
38 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.60077571 |
39 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.59780386 |
40 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.57692574 |
41 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.56871031 |
42 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56826995 |
43 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.56721341 |
44 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.55319263 |
45 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.54597828 |
46 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.54287666 |
47 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.51766086 |
48 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.49811979 |
49 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.49151932 |
50 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.48742796 |
51 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.47186656 |
52 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.45793689 |
53 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.45692032 |
54 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.42749405 |
55 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.42452646 |
56 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.41743173 |
57 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.39117436 |
58 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.38881046 |
59 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.38440305 |
60 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.37523538 |
61 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.37514207 |
62 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.36716814 |
63 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.36397127 |
64 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.35535265 |
65 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.32803386 |
66 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.32377339 |
67 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.30920526 |
68 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.30531833 |
69 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.30413505 |
70 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.30192640 |
71 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.29898087 |
72 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.29219485 |
73 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.28767177 |
74 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.27923818 |
75 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.27810226 |
76 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.27594471 |
77 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.26979782 |
78 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.26917923 |
79 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25078075 |
80 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.25063434 |
81 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.23974548 |
82 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.23412948 |
83 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.22458104 |
84 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.22314035 |
85 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.21336048 |
86 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.20512219 |
87 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.20483559 |
88 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.20317635 |
89 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.20259857 |
90 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.18969455 |
91 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.18872534 |
92 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18661227 |
93 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.16984601 |
94 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.15649639 |
95 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.15367601 |
96 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.15000615 |
97 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.14536415 |
98 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.14300686 |
99 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.12770647 |
100 | * SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.12405810 |
101 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.11155143 |
102 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.09292995 |
103 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.09096171 |
104 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.08956470 |
105 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.08956470 |
106 | P68_20966046_ChIP-Seq_HELA_Human | 1.08806839 |
107 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.07831673 |
108 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.06338465 |
109 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.06167390 |
110 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.05956409 |
111 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.05612329 |
112 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.05009864 |
113 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.03910509 |
114 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.03660756 |
115 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.03439606 |
116 | * AR_19668381_ChIP-Seq_PC3_Human | 1.01293624 |
117 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.00755153 |
118 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.00290782 |
119 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.00288586 |
120 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.00030002 |
121 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99970230 |
122 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.99315468 |
123 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.99084814 |
124 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.98832464 |
125 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.97980861 |
126 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.97685431 |
127 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.97486709 |
128 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.96729659 |
129 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.96431392 |
130 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.96367855 |
131 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.96366499 |
132 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.95185863 |
133 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.95020458 |
134 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.94979574 |
135 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.94098819 |
136 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.93836158 |
137 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.93836158 |
138 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.93688977 |
139 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.93501253 |
140 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.93410115 |
141 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.91025258 |
142 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.88705079 |
143 | CJUN_26792858_Chip-Seq_BT549_Human | 0.88332094 |
144 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.87445856 |
145 | * ATF3_27146783_Chip-Seq_COLON_Human | 0.86867286 |
146 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.86847743 |
147 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.86602633 |
148 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.83395669 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.91435585 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.51680349 |
3 | MP0005503_abnormal_tendon_morphology | 3.40051829 |
4 | MP0003283_abnormal_digestive_organ | 3.32087178 |
5 | MP0003705_abnormal_hypodermis_morpholog | 2.97431728 |
6 | MP0005275_abnormal_skin_tensile | 2.93185203 |
7 | MP0005623_abnormal_meninges_morphology | 2.82606564 |
8 | MP0000013_abnormal_adipose_tissue | 2.63879308 |
9 | MP0009780_abnormal_chondrocyte_physiolo | 2.57925354 |
10 | MP0003279_aneurysm | 2.46291067 |
11 | MP0004858_abnormal_nervous_system | 2.32420489 |
12 | MP0002909_abnormal_adrenal_gland | 2.26322261 |
13 | MP0001849_ear_inflammation | 2.26071373 |
14 | MP0002060_abnormal_skin_morphology | 2.14580677 |
15 | MP0001958_emphysema | 2.13537978 |
16 | MP0004272_abnormal_basement_membrane | 2.09012135 |
17 | MP0000751_myopathy | 2.01189360 |
18 | MP0003122_maternal_imprinting | 1.95922365 |
19 | MP0003635_abnormal_synaptic_transmissio | 1.93848079 |
20 | MP0000566_synostosis | 1.91903707 |
21 | MP0002877_abnormal_melanocyte_morpholog | 1.89741815 |
22 | MP0005058_abnormal_lysosome_morphology | 1.84300890 |
23 | MP0001299_abnormal_eye_distance/ | 1.80920151 |
24 | MP0005257_abnormal_intraocular_pressure | 1.74906349 |
25 | MP0004270_analgesia | 1.73652142 |
26 | MP0009840_abnormal_foam_cell | 1.68634863 |
27 | MP0005409_darkened_coat_color | 1.67432531 |
28 | MP0000579_abnormal_nail_morphology | 1.62835259 |
29 | MP0001348_abnormal_lacrimal_gland | 1.60307867 |
30 | MP0000762_abnormal_tongue_morphology | 1.56314480 |
31 | MP0000003_abnormal_adipose_tissue | 1.54400287 |
32 | MP0002896_abnormal_bone_mineralization | 1.53118885 |
33 | MP0002837_dystrophic_cardiac_calcinosis | 1.51869085 |
34 | MP0005360_urolithiasis | 1.48866745 |
35 | MP0002063_abnormal_learning/memory/cond | 1.46356862 |
36 | MP0002249_abnormal_larynx_morphology | 1.45520047 |
37 | MP0005508_abnormal_skeleton_morphology | 1.45002372 |
38 | MP0000767_abnormal_smooth_muscle | 1.44840870 |
39 | MP0008961_abnormal_basal_metabolism | 1.42825258 |
40 | MP0003329_amyloid_beta_deposits | 1.37402470 |
41 | MP0000534_abnormal_ureter_morphology | 1.36447030 |
42 | MP0004233_abnormal_muscle_weight | 1.36253714 |
43 | MP0002089_abnormal_postnatal_growth/wei | 1.34615956 |
44 | MP0003566_abnormal_cell_adhesion | 1.34368006 |
45 | MP0003941_abnormal_skin_development | 1.34130263 |
46 | MP0003091_abnormal_cell_migration | 1.32301066 |
47 | MP0000467_abnormal_esophagus_morphology | 1.32063818 |
48 | MP0010368_abnormal_lymphatic_system | 1.28642363 |
49 | MP0003045_fibrosis | 1.28237968 |
50 | MP0009384_cardiac_valve_regurgitation | 1.24374154 |
51 | MP0002295_abnormal_pulmonary_circulatio | 1.24164958 |
52 | MP0002108_abnormal_muscle_morphology | 1.21616327 |
53 | MP0005171_absent_coat_pigmentation | 1.21306507 |
54 | MP0000462_abnormal_digestive_system | 1.21005157 |
55 | MP0002234_abnormal_pharynx_morphology | 1.20761326 |
56 | MP0003453_abnormal_keratinocyte_physiol | 1.17358720 |
57 | MP0002734_abnormal_mechanical_nocicepti | 1.16977013 |
58 | MP0003385_abnormal_body_wall | 1.14204669 |
59 | MP0006054_spinal_hemorrhage | 1.13691533 |
60 | MP0010386_abnormal_urinary_bladder | 1.13588668 |
61 | MP0003942_abnormal_urinary_system | 1.11274448 |
62 | MP0008260_abnormal_autophagy | 1.09544006 |
63 | MP0004811_abnormal_neuron_physiology | 1.07387344 |
64 | MP0000955_abnormal_spinal_cord | 1.07366019 |
65 | MP0002733_abnormal_thermal_nociception | 1.06733716 |
66 | MP0003172_abnormal_lysosome_physiology | 1.06555421 |
67 | MP0005076_abnormal_cell_differentiation | 1.06274886 |
68 | MP0009745_abnormal_behavioral_response | 1.05544666 |
69 | MP0002064_seizures | 1.04758139 |
70 | MP0004145_abnormal_muscle_electrophysio | 1.04719003 |
71 | MP0000428_abnormal_craniofacial_morphol | 1.04335123 |
72 | MP0009053_abnormal_anal_canal | 1.01054296 |
73 | MP0010030_abnormal_orbit_morphology | 1.00903827 |
74 | MP0002572_abnormal_emotion/affect_behav | 1.00874105 |
75 | MP0002184_abnormal_innervation | 1.00857831 |
76 | MP0003115_abnormal_respiratory_system | 1.00731807 |
77 | MP0004084_abnormal_cardiac_muscle | 1.00184864 |
78 | MP0001968_abnormal_touch/_nociception | 0.99315967 |
79 | MP0002254_reproductive_system_inflammat | 0.97781246 |
80 | MP0005451_abnormal_body_composition | 0.96785747 |
81 | MP0002735_abnormal_chemical_nociception | 0.94663454 |
82 | MP0005501_abnormal_skin_physiology | 0.94333252 |
83 | MP0003119_abnormal_digestive_system | 0.94276463 |
84 | MP0001915_intracranial_hemorrhage | 0.94003603 |
85 | MP0010352_gastrointestinal_tract_polyps | 0.93761034 |
86 | MP0002796_impaired_skin_barrier | 0.93326406 |
87 | MP0001970_abnormal_pain_threshold | 0.92999296 |
88 | MP0004264_abnormal_extraembryonic_tissu | 0.90641423 |
89 | MP0003880_abnormal_central_pattern | 0.90484818 |
90 | MP0001944_abnormal_pancreas_morphology | 0.89356616 |
91 | MP0000163_abnormal_cartilage_morphology | 0.87512732 |
92 | MP0009250_abnormal_appendicular_skeleto | 0.87082456 |
93 | MP0001243_abnormal_dermal_layer | 0.86752678 |
94 | MP0000538_abnormal_urinary_bladder | 0.86748624 |
95 | MP0000733_abnormal_muscle_development | 0.86340491 |
96 | MP0000747_muscle_weakness | 0.84137301 |
97 | MP0009046_muscle_twitch | 0.82859357 |
98 | MP0008569_lethality_at_weaning | 0.82724064 |
99 | MP0004134_abnormal_chest_morphology | 0.82270129 |
100 | MP0000759_abnormal_skeletal_muscle | 0.82207225 |
101 | MP0003123_paternal_imprinting | 0.81083543 |
102 | MP0000750_abnormal_muscle_regeneration | 0.80356007 |
103 | MP0006138_congestive_heart_failure | 0.79978245 |
104 | MP0010771_integument_phenotype | 0.79732915 |
105 | MP0005197_abnormal_uvea_morphology | 0.78963734 |
106 | MP0000678_abnormal_parathyroid_gland | 0.78694241 |
107 | MP0000778_abnormal_nervous_system | 0.78281962 |
108 | MP0001661_extended_life_span | 0.77642515 |
109 | MP0001440_abnormal_grooming_behavior | 0.77417644 |
110 | MP0002269_muscular_atrophy | 0.76857433 |
111 | MP0005023_abnormal_wound_healing | 0.76594283 |
112 | MP0002116_abnormal_craniofacial_bone | 0.76458174 |
113 | MP0002272_abnormal_nervous_system | 0.75913825 |
114 | MP0004087_abnormal_muscle_fiber | 0.75342153 |
115 | MP0003634_abnormal_glial_cell | 0.75000160 |
116 | MP0002736_abnormal_nociception_after | 0.74789600 |
117 | MP0000858_altered_metastatic_potential | 0.74287946 |
118 | MP0002653_abnormal_ependyma_morphology | 0.73969679 |
119 | MP0000432_abnormal_head_morphology | 0.73388447 |
120 | MP0005375_adipose_tissue_phenotype | 0.73380624 |
121 | MP0002098_abnormal_vibrissa_morphology | 0.72066693 |
122 | MP0002115_abnormal_skeleton_extremities | 0.70941525 |
123 | MP0002557_abnormal_social/conspecific_i | 0.70713326 |
124 | MP0002168_other_aberrant_phenotype | 0.69986565 |
125 | MP0005595_abnormal_vascular_smooth | 0.69854349 |
126 | MP0001501_abnormal_sleep_pattern | 0.69792863 |
127 | MP0002932_abnormal_joint_morphology | 0.69102361 |
128 | MP0002697_abnormal_eye_size | 0.68467555 |
129 | MP0001614_abnormal_blood_vessel | 0.68409557 |
130 | MP0000537_abnormal_urethra_morphology | 0.68030217 |
131 | MP0010234_abnormal_vibrissa_follicle | 0.67775307 |
132 | MP0002882_abnormal_neuron_morphology | 0.66721401 |
133 | MP0005193_abnormal_anterior_eye | 0.66181114 |
134 | MP0000749_muscle_degeneration | 0.66146332 |
135 | MP0005330_cardiomyopathy | 0.65381997 |
136 | MP0001177_atelectasis | 0.64961658 |
137 | MP0006276_abnormal_autonomic_nervous | 0.64851011 |
138 | MP0001542_abnormal_bone_strength | 0.64704810 |
139 | MP0004133_heterotaxia | 0.64017918 |
140 | MP0002113_abnormal_skeleton_development | 0.63735251 |
141 | MP0003959_abnormal_lean_body | 0.63126004 |
142 | MP0010630_abnormal_cardiac_muscle | 0.62392736 |
143 | MP0000049_abnormal_middle_ear | 0.62359475 |
144 | MP0005390_skeleton_phenotype | 0.61933984 |
145 | MP0003755_abnormal_palate_morphology | 0.61129395 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 5.87047212 |
2 | Premature rupture of membranes (HP:0001788) | 5.08415561 |
3 | Shallow orbits (HP:0000586) | 3.82405978 |
4 | Cerebral aneurysm (HP:0004944) | 3.73068243 |
5 | Bladder diverticulum (HP:0000015) | 3.54933369 |
6 | Ulnar bowing (HP:0003031) | 3.36270816 |
7 | Ankle contracture (HP:0006466) | 3.32044468 |
8 | Broad metatarsal (HP:0001783) | 3.17038776 |
9 | Bowel diverticulosis (HP:0005222) | 3.05048276 |
10 | Dilatation of the ascending aorta (HP:0005111) | 3.05003393 |
11 | Abnormality of dentin (HP:0010299) | 3.04958428 |
12 | Cervical subluxation (HP:0003308) | 2.96624030 |
13 | Wrist flexion contracture (HP:0001239) | 2.96309240 |
14 | Genu recurvatum (HP:0002816) | 2.94152603 |
15 | Atrophic scars (HP:0001075) | 2.91298348 |
16 | Aortic dissection (HP:0002647) | 2.87032591 |
17 | Distal upper limb amyotrophy (HP:0007149) | 2.83354292 |
18 | Upper limb amyotrophy (HP:0009129) | 2.83354292 |
19 | Soft skin (HP:0000977) | 2.81127196 |
20 | Fragile skin (HP:0001030) | 2.76307298 |
21 | Hypercortisolism (HP:0001578) | 2.64195001 |
22 | Hand muscle atrophy (HP:0009130) | 2.63531869 |
23 | Hypoventilation (HP:0002791) | 2.62157272 |
24 | Neonatal short-limb short stature (HP:0008921) | 2.52386553 |
25 | Deep venous thrombosis (HP:0002625) | 2.51987790 |
26 | Aortic aneurysm (HP:0004942) | 2.50670301 |
27 | Hyperextensible skin (HP:0000974) | 2.49699450 |
28 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.49424176 |
29 | Congenital glaucoma (HP:0001087) | 2.45865935 |
30 | Premature skin wrinkling (HP:0100678) | 2.45249163 |
31 | Pterygium (HP:0001059) | 2.44403271 |
32 | Peritonitis (HP:0002586) | 2.42872241 |
33 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.41096381 |
34 | Wormian bones (HP:0002645) | 2.40584839 |
35 | Vascular tortuosity (HP:0004948) | 2.38679393 |
36 | Mitral valve prolapse (HP:0001634) | 2.38299539 |
37 | Overgrowth (HP:0001548) | 2.38054237 |
38 | Spinal rigidity (HP:0003306) | 2.34927384 |
39 | Vertebral compression fractures (HP:0002953) | 2.32940192 |
40 | Increased variability in muscle fiber diameter (HP:0003557) | 2.30598322 |
41 | Disproportionate tall stature (HP:0001519) | 2.26986004 |
42 | Mitral stenosis (HP:0001718) | 2.24728482 |
43 | Blue sclerae (HP:0000592) | 2.24528697 |
44 | Abnormality of the Achilles tendon (HP:0005109) | 2.21355184 |
45 | Buphthalmos (HP:0000557) | 2.20322696 |
46 | Difficulty climbing stairs (HP:0003551) | 2.19274478 |
47 | Aneurysm (HP:0002617) | 2.19192555 |
48 | Visual hallucinations (HP:0002367) | 2.18058077 |
49 | Type 1 muscle fiber predominance (HP:0003803) | 2.17230128 |
50 | Abnormal delivery (HP:0001787) | 2.17036775 |
51 | Arterial tortuosity (HP:0005116) | 2.11949300 |
52 | Asymmetry of the thorax (HP:0001555) | 2.10720487 |
53 | Insomnia (HP:0100785) | 2.09945092 |
54 | Short nail (HP:0001799) | 2.08349045 |
55 | Myokymia (HP:0002411) | 2.07772232 |
56 | Generalized amyotrophy (HP:0003700) | 2.06643507 |
57 | Distal lower limb muscle weakness (HP:0009053) | 2.05898240 |
58 | Broad face (HP:0000283) | 2.04966686 |
59 | Bowed forearm bones (HP:0003956) | 2.02268272 |
60 | Bowing of the arm (HP:0006488) | 2.02268272 |
61 | Bronchomalacia (HP:0002780) | 2.02066905 |
62 | Renal duplication (HP:0000075) | 2.01737894 |
63 | Natal tooth (HP:0000695) | 2.01660897 |
64 | Stridor (HP:0010307) | 2.01328784 |
65 | Hyperacusis (HP:0010780) | 1.99718601 |
66 | Follicular hyperkeratosis (HP:0007502) | 1.98567260 |
67 | Focal seizures (HP:0007359) | 1.95415338 |
68 | Supranuclear gaze palsy (HP:0000605) | 1.95033534 |
69 | Deviation of the hallux (HP:0010051) | 1.94860802 |
70 | Turricephaly (HP:0000262) | 1.94668163 |
71 | Spinal cord compression (HP:0002176) | 1.94566515 |
72 | Enlarged penis (HP:0000040) | 1.93104752 |
73 | J-shaped sella turcica (HP:0002680) | 1.92567635 |
74 | Thin bony cortex (HP:0002753) | 1.92508561 |
75 | Coronal craniosynostosis (HP:0004440) | 1.91920200 |
76 | Distal lower limb amyotrophy (HP:0008944) | 1.91904163 |
77 | Increased connective tissue (HP:0009025) | 1.90662051 |
78 | Coxa vara (HP:0002812) | 1.90359227 |
79 | Advanced eruption of teeth (HP:0006288) | 1.89126206 |
80 | Aortic regurgitation (HP:0001659) | 1.88859710 |
81 | Abnormality of carpal bone ossification (HP:0006257) | 1.88642225 |
82 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.88199625 |
83 | Joint laxity (HP:0001388) | 1.87843623 |
84 | Hallux valgus (HP:0001822) | 1.86293644 |
85 | Osteopenia (HP:0000938) | 1.86236436 |
86 | Slender build (HP:0001533) | 1.85755468 |
87 | Obstructive sleep apnea (HP:0002870) | 1.85561720 |
88 | Broad ribs (HP:0000885) | 1.84765910 |
89 | Achilles tendon contracture (HP:0001771) | 1.84465543 |
90 | Striae distensae (HP:0001065) | 1.83020755 |
91 | Atonic seizures (HP:0010819) | 1.82524717 |
92 | Mild short stature (HP:0003502) | 1.82000501 |
93 | Flat cornea (HP:0007720) | 1.80356290 |
94 | Back pain (HP:0003418) | 1.80229333 |
95 | Long toe (HP:0010511) | 1.79871749 |
96 | Megalencephaly (HP:0001355) | 1.78671469 |
97 | Abnormal ossification of hand bones (HP:0005921) | 1.78383470 |
98 | Biconcave vertebral bodies (HP:0004586) | 1.78224788 |
99 | Abnormality of the acetabulum (HP:0003170) | 1.77428658 |
100 | Renovascular hypertension (HP:0100817) | 1.77281422 |
101 | Cerebral inclusion bodies (HP:0100314) | 1.75170304 |
102 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.73889972 |
103 | Osteolytic defects of the hand bones (HP:0009699) | 1.73889972 |
104 | Narrow nasal bridge (HP:0000446) | 1.73529338 |
105 | Thin skin (HP:0000963) | 1.73349835 |
106 | Hemorrhage of the eye (HP:0011885) | 1.73201105 |
107 | Round ear (HP:0100830) | 1.72068449 |
108 | Joint stiffness (HP:0001387) | 1.71953340 |
109 | Arnold-Chiari malformation (HP:0002308) | 1.71756521 |
110 | Flat acetabular roof (HP:0003180) | 1.70907236 |
111 | Lower limb amyotrophy (HP:0007210) | 1.70385960 |
112 | Wide anterior fontanel (HP:0000260) | 1.69928176 |
113 | Cardiovascular calcification (HP:0011915) | 1.69667690 |
114 | Trismus (HP:0000211) | 1.69025712 |
115 | Breech presentation (HP:0001623) | 1.68725543 |
116 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.68574078 |
117 | Aplasia of the phalanges of the hand (HP:0009802) | 1.68574078 |
118 | Aplasia involving bones of the extremities (HP:0009825) | 1.68574078 |
119 | Pointed chin (HP:0000307) | 1.68525885 |
120 | Neoplasm of the heart (HP:0100544) | 1.67766485 |
121 | Osteoarthritis (HP:0002758) | 1.66882375 |
122 | Hyperparathyroidism (HP:0000843) | 1.66050256 |
123 | Elbow flexion contracture (HP:0002987) | 1.65892157 |
124 | Mitral regurgitation (HP:0001653) | 1.65391948 |
125 | Broad long bones (HP:0005622) | 1.64214087 |
126 | Ankyloglossia (HP:0010296) | 1.63116152 |
127 | Ankle clonus (HP:0011448) | 1.62868100 |
128 | Failure to thrive in infancy (HP:0001531) | 1.61543303 |
129 | Agitation (HP:0000713) | 1.61253509 |
130 | Abnormality of the lower motor neuron (HP:0002366) | 1.60506666 |
131 | Depression (HP:0000716) | 1.60356156 |
132 | Papilledema (HP:0001085) | 1.59151072 |
133 | Hemiplegia (HP:0002301) | 1.58180320 |
134 | Thin ribs (HP:0000883) | 1.58126029 |
135 | Scapular winging (HP:0003691) | 1.54252353 |
136 | Thoracolumbar scoliosis (HP:0002944) | 1.51622670 |
137 | Platyspondyly (HP:0000926) | 1.51542934 |
138 | Abnormality of oral frenula (HP:0000190) | 1.51198916 |
139 | Action tremor (HP:0002345) | 1.50807507 |
140 | Inguinal hernia (HP:0000023) | 1.50521972 |
141 | Bradycardia (HP:0001662) | 1.50307862 |
142 | Torticollis (HP:0000473) | 1.50234862 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.06406270 |
2 | PRKD3 | 3.08517527 |
3 | NTRK3 | 2.82315105 |
4 | MST1R | 2.81022961 |
5 | DDR2 | 2.80290471 |
6 | PDGFRA | 2.77376304 |
7 | LATS2 | 2.71068693 |
8 | MAP3K9 | 2.63927394 |
9 | NTRK1 | 2.52837672 |
10 | SMG1 | 2.51178320 |
11 | FGFR4 | 2.49189577 |
12 | PAK6 | 2.16625456 |
13 | PKN2 | 2.13900915 |
14 | KSR2 | 2.10353305 |
15 | RIPK1 | 2.03382375 |
16 | SCYL2 | 1.88296864 |
17 | MINK1 | 1.87574752 |
18 | PAK3 | 1.86132616 |
19 | MARK1 | 1.76600305 |
20 | CAMKK1 | 1.68072386 |
21 | TTN | 1.67828095 |
22 | MAP3K2 | 1.64087194 |
23 | IRAK3 | 1.63858964 |
24 | ERN1 | 1.63050012 |
25 | MYLK | 1.62346700 |
26 | EPHA4 | 1.58241930 |
27 | PTK2 | 1.54902569 |
28 | KSR1 | 1.52306817 |
29 | CDK12 | 1.40355422 |
30 | TAOK1 | 1.39812846 |
31 | BMX | 1.39181989 |
32 | FER | 1.37863261 |
33 | PRKCH | 1.36747648 |
34 | EPHB1 | 1.36481345 |
35 | TYRO3 | 1.34613644 |
36 | RET | 1.31988469 |
37 | LMTK2 | 1.28680952 |
38 | NTRK2 | 1.28480971 |
39 | SIK1 | 1.25048412 |
40 | MAP3K4 | 1.25027742 |
41 | UHMK1 | 1.23720425 |
42 | EPHB2 | 1.23006892 |
43 | DAPK2 | 1.22939270 |
44 | CDC42BPA | 1.22393351 |
45 | NME2 | 1.18931903 |
46 | ICK | 1.12922832 |
47 | PAK2 | 1.07338490 |
48 | PIM2 | 1.07002665 |
49 | PRPF4B | 1.06045793 |
50 | STK38 | 1.05912250 |
51 | ALK | 1.05437582 |
52 | TESK1 | 1.03312213 |
53 | ARAF | 1.01193434 |
54 | MAP3K1 | 1.00071570 |
55 | CDK5 | 0.98317448 |
56 | MAP2K1 | 0.97437854 |
57 | PHKG1 | 0.94914222 |
58 | PHKG2 | 0.94914222 |
59 | PTK6 | 0.94070189 |
60 | MAP3K3 | 0.92898393 |
61 | MAP3K10 | 0.91322894 |
62 | MUSK | 0.90714441 |
63 | CAMKK2 | 0.89589433 |
64 | PTK2B | 0.88708318 |
65 | DMPK | 0.86515106 |
66 | PDGFRB | 0.82964960 |
67 | PRKD2 | 0.82566982 |
68 | MAPKAPK3 | 0.80652274 |
69 | CDK14 | 0.80364048 |
70 | LIMK1 | 0.79739534 |
71 | ROCK1 | 0.79573466 |
72 | MARK2 | 0.79298880 |
73 | ERBB4 | 0.77224309 |
74 | PLK2 | 0.76745683 |
75 | CDK15 | 0.73874773 |
76 | CDK18 | 0.73673303 |
77 | DAPK3 | 0.72305448 |
78 | HIPK2 | 0.72212709 |
79 | MAP3K6 | 0.71546392 |
80 | SIK2 | 0.71542184 |
81 | MTOR | 0.71187130 |
82 | FGFR1 | 0.71068489 |
83 | PASK | 0.69410537 |
84 | EEF2K | 0.67665243 |
85 | EPHA3 | 0.67262405 |
86 | PRKG2 | 0.67100420 |
87 | TAOK2 | 0.66469341 |
88 | LATS1 | 0.66164727 |
89 | MOS | 0.66149094 |
90 | PRKCG | 0.64444370 |
91 | NEK9 | 0.64321724 |
92 | CDK11A | 0.62823150 |
93 | PDPK1 | 0.62138016 |
94 | ILK | 0.61921533 |
95 | DYRK1B | 0.61551651 |
96 | RPS6KA2 | 0.59950382 |
97 | GRK5 | 0.57538031 |
98 | CAMK1G | 0.57255071 |
99 | CAMK2G | 0.57210403 |
100 | ABL2 | 0.57170062 |
101 | ROCK2 | 0.54638896 |
102 | FLT3 | 0.54398759 |
103 | RPS6KC1 | 0.52929744 |
104 | RPS6KL1 | 0.52929744 |
105 | EPHA2 | 0.51015522 |
106 | MET | 0.50752642 |
107 | FGFR3 | 0.49497728 |
108 | PRKD1 | 0.49080043 |
109 | BRAF | 0.48856959 |
110 | MAP2K2 | 0.46828006 |
111 | PRKCI | 0.46193897 |
112 | CDK7 | 0.44979724 |
113 | PAK4 | 0.42550539 |
114 | STK11 | 0.41015688 |
115 | WNK1 | 0.40980588 |
116 | CAMK2A | 0.40153764 |
117 | PRKCE | 0.40126092 |
118 | CAMK2B | 0.39469722 |
119 | MAPK15 | 0.38618409 |
120 | MAPK11 | 0.37847942 |
121 | SRC | 0.37424061 |
122 | MAP2K4 | 0.37111586 |
123 | AKT2 | 0.36751605 |
124 | WNK4 | 0.35635161 |
125 | GSK3A | 0.35332826 |
126 | CAMK1 | 0.35316918 |
127 | ADRBK1 | 0.34609335 |
128 | INSR | 0.33466801 |
129 | CAMK2D | 0.32366135 |
130 | DAPK1 | 0.32345668 |
131 | RPS6KA6 | 0.31856814 |
132 | MAP3K8 | 0.31627570 |
133 | MAP3K11 | 0.30976601 |
134 | LRRK2 | 0.30551053 |
135 | MAPKAPK2 | 0.29498750 |
136 | TGFBR2 | 0.29351575 |
137 | FYN | 0.29320669 |
138 | PRKCZ | 0.29313654 |
139 | TESK2 | 0.28377231 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.22055820 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.15588834 |
3 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.09683317 |
4 | Other glycan degradation_Homo sapiens_hsa00511 | 2.08932546 |
5 | Insulin secretion_Homo sapiens_hsa04911 | 1.98179941 |
6 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.87381531 |
7 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.79183502 |
8 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.76548425 |
9 | Galactose metabolism_Homo sapiens_hsa00052 | 1.68536036 |
10 | Circadian entrainment_Homo sapiens_hsa04713 | 1.66116739 |
11 | Long-term potentiation_Homo sapiens_hsa04720 | 1.65536186 |
12 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.61633513 |
13 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.58212057 |
14 | Cocaine addiction_Homo sapiens_hsa05030 | 1.54182282 |
15 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.52884982 |
16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.48624039 |
17 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.48478020 |
18 | Olfactory transduction_Homo sapiens_hsa04740 | 1.46858718 |
19 | GABAergic synapse_Homo sapiens_hsa04727 | 1.45746153 |
20 | Focal adhesion_Homo sapiens_hsa04510 | 1.44962331 |
21 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.43963251 |
22 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.43098561 |
23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.42995086 |
24 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.42067714 |
25 | Glioma_Homo sapiens_hsa05214 | 1.41539904 |
26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.40435959 |
27 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.39910516 |
28 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.38108939 |
29 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.38022238 |
30 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.36382245 |
31 | Bladder cancer_Homo sapiens_hsa05219 | 1.36078824 |
32 | Gap junction_Homo sapiens_hsa04540 | 1.35822157 |
33 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.34462171 |
34 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.33874379 |
35 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.32997330 |
36 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.30594176 |
37 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.30462146 |
38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.28973700 |
39 | Salivary secretion_Homo sapiens_hsa04970 | 1.28087826 |
40 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.27663348 |
41 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.26234655 |
42 | Melanogenesis_Homo sapiens_hsa04916 | 1.25120128 |
43 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.24847451 |
44 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.24370055 |
45 | Sulfur relay system_Homo sapiens_hsa04122 | 1.23604131 |
46 | Morphine addiction_Homo sapiens_hsa05032 | 1.22603041 |
47 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.22201634 |
48 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.21889464 |
49 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.19171748 |
50 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.17607933 |
51 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.17173074 |
52 | * Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.16259246 |
53 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.16056825 |
54 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.15524738 |
55 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.15150971 |
56 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.14219129 |
57 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.09125648 |
58 | Axon guidance_Homo sapiens_hsa04360 | 1.08560017 |
59 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.07643229 |
60 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.07621397 |
61 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.04660246 |
62 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.02431338 |
63 | Amoebiasis_Homo sapiens_hsa05146 | 1.02075322 |
64 | Taste transduction_Homo sapiens_hsa04742 | 1.01921984 |
65 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.01532602 |
66 | Renin secretion_Homo sapiens_hsa04924 | 1.00280219 |
67 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.99551283 |
68 | Long-term depression_Homo sapiens_hsa04730 | 0.99299389 |
69 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.99145158 |
70 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.98421682 |
71 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.97627339 |
72 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.97343012 |
73 | Endometrial cancer_Homo sapiens_hsa05213 | 0.97039340 |
74 | Thyroid cancer_Homo sapiens_hsa05216 | 0.96973441 |
75 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.95187450 |
76 | Bile secretion_Homo sapiens_hsa04976 | 0.94443918 |
77 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.93799824 |
78 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.93443068 |
79 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.92568770 |
80 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.90530923 |
81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.89918061 |
82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.89320761 |
83 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.89158883 |
84 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.88878186 |
85 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.87148919 |
86 | Prion diseases_Homo sapiens_hsa05020 | 0.86103664 |
87 | Adherens junction_Homo sapiens_hsa04520 | 0.84775886 |
88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.84753187 |
89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.84530214 |
90 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.84261138 |
91 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.84166672 |
92 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.82789111 |
93 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.82676200 |
94 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.82586790 |
95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.81799256 |
96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.81381781 |
97 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.80941491 |
98 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.80805478 |
99 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.80501696 |
100 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.80124492 |
101 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.79145666 |
102 | Lysosome_Homo sapiens_hsa04142 | 0.79073230 |
103 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.78877023 |
104 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.77413863 |
105 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.77211641 |
106 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.74855582 |
107 | Colorectal cancer_Homo sapiens_hsa05210 | 0.74571901 |
108 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.74294074 |
109 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.73936264 |
110 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.73821638 |
111 | Melanoma_Homo sapiens_hsa05218 | 0.72831719 |
112 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.72670223 |
113 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.71614632 |
114 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.71540896 |
115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.71451640 |
116 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.71267746 |
117 | Endocytosis_Homo sapiens_hsa04144 | 0.70764771 |
118 | Carbon metabolism_Homo sapiens_hsa01200 | 0.69425805 |
119 | Tight junction_Homo sapiens_hsa04530 | 0.67897932 |
120 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.67789417 |
121 | Lysine degradation_Homo sapiens_hsa00310 | 0.67695366 |
122 | Insulin resistance_Homo sapiens_hsa04931 | 0.67557262 |
123 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.66460264 |
124 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.64830463 |
125 | Pathways in cancer_Homo sapiens_hsa05200 | 0.64562040 |
126 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.64352313 |
127 | Prostate cancer_Homo sapiens_hsa05215 | 0.63978429 |
128 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.63872167 |
129 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.62983601 |
130 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.62443018 |
131 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.62435691 |
132 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61259640 |
133 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.60143609 |
134 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.59836193 |
135 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.59671778 |
136 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.58713104 |
137 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55879634 |
138 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.54128287 |
139 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.46985295 |
140 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.46616285 |
141 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.45803417 |
142 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44587887 |