CHPF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1low-density lipoprotein particle clearance (GO:0034383)3.73075888
2apoptotic cell clearance (GO:0043277)3.69013577
3COPI coating of Golgi vesicle (GO:0048205)3.62350408
4Golgi transport vesicle coating (GO:0048200)3.62350408
5hemidesmosome assembly (GO:0031581)3.51790605
6negative regulation of erythrocyte differentiation (GO:0045647)3.49975855
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.43800760
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.43800760
9regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.41223568
10negative regulation of fatty acid transport (GO:2000192)3.31132520
11mannose metabolic process (GO:0006013)3.22485106
12cell adhesion mediated by integrin (GO:0033627)3.21245587
13regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.20575858
14barbed-end actin filament capping (GO:0051016)3.16436621
15pinocytosis (GO:0006907)3.15939145
16protein heterotrimerization (GO:0070208)3.13297440
17hypotonic response (GO:0006971)3.05614008
18negative regulation of fibrinolysis (GO:0051918)3.02317168
19stress fiber assembly (GO:0043149)3.00113039
20cell-substrate adherens junction assembly (GO:0007045)2.94874036
21focal adhesion assembly (GO:0048041)2.94874036
22cytoskeletal anchoring at plasma membrane (GO:0007016)2.94018197
23collagen fibril organization (GO:0030199)2.92204315
24regulation of fatty acid beta-oxidation (GO:0031998)2.89393377
25activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.87488857
26endodermal cell differentiation (GO:0035987)2.85551078
27positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.85048550
28antigen processing and presentation of endogenous antigen (GO:0019883)2.82470080
29regulation of extracellular matrix disassembly (GO:0010715)2.82136294
30maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.80345637
31protein retention in ER lumen (GO:0006621)2.78002332
32hyaluronan catabolic process (GO:0030214)2.77757932
33positive regulation of receptor recycling (GO:0001921)2.76481139
34positive regulation of fibroblast migration (GO:0010763)2.75493962
35positive regulation of histone deacetylation (GO:0031065)2.75076600
36vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.74990886
37plasma membrane repair (GO:0001778)2.72954960
38regulation of cholesterol storage (GO:0010885)2.70894183
39positive regulation of nuclease activity (GO:0032075)2.69891361
40protein localization to endosome (GO:0036010)2.66172937
41response to peptidoglycan (GO:0032494)2.66007977
42regulation of cholesterol homeostasis (GO:2000188)2.65715836
43negative regulation of cell size (GO:0045792)2.64822896
44embryonic process involved in female pregnancy (GO:0060136)2.64321337
45retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.64019814
46axon extension involved in axon guidance (GO:0048846)2.60265171
47neuron projection extension involved in neuron projection guidance (GO:1902284)2.60265171
48response to muramyl dipeptide (GO:0032495)2.60200331
49cell migration involved in heart development (GO:0060973)2.60190231
50skin morphogenesis (GO:0043589)2.59304066
51antigen processing and presentation via MHC class Ib (GO:0002475)2.58318545
52positive regulation by symbiont of host defense response (GO:0052509)2.57361631
53modulation by symbiont of host defense response (GO:0052031)2.57361631
54modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.57361631
55modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.57361631
56positive regulation by organism of defense response of other organism involved in symbiotic interact2.57361631
57modulation by symbiont of host immune response (GO:0052553)2.57361631
58alanine transport (GO:0032328)2.56842409
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.55372167
60wound healing, spreading of epidermal cells (GO:0035313)2.55161640
61peptidyl-glutamic acid carboxylation (GO:0017187)2.52862295
62protein carboxylation (GO:0018214)2.52862295
63insulin-like growth factor receptor signaling pathway (GO:0048009)2.51386527
64positive regulation of extracellular matrix organization (GO:1903055)2.51101924
65semaphorin-plexin signaling pathway (GO:0071526)2.49820126
66positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.48653046
67positive regulation of p38MAPK cascade (GO:1900745)2.48593890
68alpha-linolenic acid metabolic process (GO:0036109)2.48301199
69heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.47520019
70regulation of ARF protein signal transduction (GO:0032012)2.46801693
71regulation of macrophage cytokine production (GO:0010935)2.46331882
72endoplasmic reticulum unfolded protein response (GO:0030968)2.45433064
73venous blood vessel morphogenesis (GO:0048845)2.45262145
74vascular endothelial growth factor signaling pathway (GO:0038084)2.45117023
75adhesion of symbiont to host (GO:0044406)2.45109702
76positive regulation of Cdc42 GTPase activity (GO:0043089)2.44780854
77fibril organization (GO:0097435)2.44061364
78negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.43497763
79modulation by symbiont of host cellular process (GO:0044068)2.43256064
80negative regulation of lipid transport (GO:0032369)2.43154750
81positive regulation of endothelial cell apoptotic process (GO:2000353)2.42190303
82positive regulation of glycogen biosynthetic process (GO:0045725)2.41876389
83positive regulation of fatty acid beta-oxidation (GO:0032000)2.41640029
84regulation of nuclease activity (GO:0032069)2.41173778
85sodium ion export (GO:0071436)2.40356963
86adhesion of symbiont to host cell (GO:0044650)2.39981536
87virion attachment to host cell (GO:0019062)2.39981536
88positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.39674711
89negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.38685353
90membrane protein ectodomain proteolysis (GO:0006509)2.38137273
91wound healing, spreading of cells (GO:0044319)2.37937897
92regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.37363621
93dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.36909220
94growth hormone receptor signaling pathway (GO:0060396)2.35322401
95bone trabecula formation (GO:0060346)2.34860101
96positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.33623309
97cellular response to unfolded protein (GO:0034620)2.32770962
98NIK/NF-kappaB signaling (GO:0038061)2.31591895
99positive regulation of triglyceride biosynthetic process (GO:0010867)2.31110860
100regulation of membrane protein ectodomain proteolysis (GO:0051043)2.31030499
101collagen metabolic process (GO:0032963)2.31014095
102plasma lipoprotein particle clearance (GO:0034381)2.30355725
103regulation of apoptotic process involved in morphogenesis (GO:1902337)2.30048829
104cortical actin cytoskeleton organization (GO:0030866)2.29852690
105collagen catabolic process (GO:0030574)2.29578401
106detection of molecule of bacterial origin (GO:0032490)2.29376223
107planar cell polarity pathway involved in neural tube closure (GO:0090179)2.28524267
108ER-nucleus signaling pathway (GO:0006984)2.28290027
109regulation of integrin activation (GO:0033623)2.27184923
110regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.26878205
111regulation of fibrinolysis (GO:0051917)2.25457152
112substrate-dependent cell migration (GO:0006929)2.25198580
113negative regulation of anoikis (GO:2000811)2.25161293
114extracellular fibril organization (GO:0043206)2.24949559
115regulation of early endosome to late endosome transport (GO:2000641)2.24547092
116integrin-mediated signaling pathway (GO:0007229)2.24322919
117cortical cytoskeleton organization (GO:0030865)2.23929297
118multicellular organismal macromolecule metabolic process (GO:0044259)2.23689265
119regulation of plasminogen activation (GO:0010755)2.23537300
120locomotory exploration behavior (GO:0035641)2.23478745
1214-hydroxyproline metabolic process (GO:0019471)2.23266302
122apoptotic process involved in morphogenesis (GO:0060561)2.23181801
123blood vessel maturation (GO:0001955)2.22992446
124negative regulation of smooth muscle cell migration (GO:0014912)2.22001721
125cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.21870504
126peptidyl-proline hydroxylation (GO:0019511)2.21606081
127type B pancreatic cell proliferation (GO:0044342)2.21548006
128extracellular matrix assembly (GO:0085029)2.21403053
129regulation of type I interferon-mediated signaling pathway (GO:0060338)2.21078323
130synaptic vesicle maturation (GO:0016188)2.20588323
131dicarboxylic acid biosynthetic process (GO:0043650)2.20168906
132positive regulation of nitric-oxide synthase activity (GO:0051000)2.18100652
133vesicle coating (GO:0006901)2.17775700
134multicellular organismal catabolic process (GO:0044243)2.14912760
135macroautophagy (GO:0016236)2.14816347
136positive regulation of blood vessel endothelial cell migration (GO:0043536)2.14634606
137activation of protein kinase A activity (GO:0034199)2.13609177
138response to fluid shear stress (GO:0034405)2.13494038
139multicellular organismal metabolic process (GO:0044236)2.13374041
140regulation of ARF GTPase activity (GO:0032312)2.12678755
141JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.12236640
142cell-substrate junction assembly (GO:0007044)2.11853509
143positive regulation of blood coagulation (GO:0030194)2.11470310
144positive regulation of hemostasis (GO:1900048)2.11470310
145adherens junction assembly (GO:0034333)2.10926653
146platelet degranulation (GO:0002576)2.10477944
147positive regulation of natural killer cell differentiation (GO:0032825)2.10446069
148cellular response to topologically incorrect protein (GO:0035967)2.10372598
149regulation of glucose import in response to insulin stimulus (GO:2001273)2.09506171
150heparan sulfate proteoglycan metabolic process (GO:0030201)2.09251724
151positive regulation of gamma-delta T cell activation (GO:0046645)2.09140584
152extracellular matrix disassembly (GO:0022617)2.08876691
153protein hydroxylation (GO:0018126)2.08601252
154keratan sulfate catabolic process (GO:0042340)2.08296575
155response to laminar fluid shear stress (GO:0034616)2.06995522
156positive regulation of glycogen metabolic process (GO:0070875)2.06239380
157basement membrane organization (GO:0071711)2.06066727
158cellular response to vitamin (GO:0071295)2.05198197

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.10156738
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.96640227
3RARG_19884340_ChIP-ChIP_MEFs_Mouse2.70955967
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.56796643
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.40517793
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.21612369
7RXR_22158963_ChIP-Seq_LIVER_Mouse2.21490511
8CLOCK_20551151_ChIP-Seq_293T_Human2.17743261
9KDM2B_26808549_Chip-Seq_SUP-B15_Human2.15237409
10LXR_22292898_ChIP-Seq_THP-1_Human2.08831592
11PPARA_22158963_ChIP-Seq_LIVER_Mouse2.00157768
12ELK3_25401928_ChIP-Seq_HUVEC_Human1.94108880
13LXR_22158963_ChIP-Seq_LIVER_Mouse1.91780830
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.86759328
15KDM2B_26808549_Chip-Seq_DND41_Human1.84654667
16EGR1_19374776_ChIP-ChIP_THP-1_Human1.84372323
17TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.82373466
18ESR2_21235772_ChIP-Seq_MCF-7_Human1.81102787
19TP63_17297297_ChIP-ChIP_HaCaT_Human1.79849532
20EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76779780
21MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.74213368
22TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.69372456
23* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.68374159
24STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67179107
25KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.66052082
26KDM2B_26808549_Chip-Seq_K562_Human1.64770445
27IRF8_22096565_ChIP-ChIP_GC-B_Human1.62602914
28NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.62330364
29TCF7_22412390_ChIP-Seq_EML_Mouse1.55825259
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.53579987
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53109541
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.49611791
33DROSHA_22980978_ChIP-Seq_HELA_Human1.48365247
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.48103559
35VDR_21846776_ChIP-Seq_THP-1_Human1.47398441
36ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.47282646
37P300_27058665_Chip-Seq_ZR-75-30cells_Human1.46098506
38TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45552757
39EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.44352192
40RACK7_27058665_Chip-Seq_MCF-7_Human1.44350654
41CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.38335736
42RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.38285537
43NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.38178115
44SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.36504612
45UBF1/2_26484160_Chip-Seq_HMECs_Human1.36161468
46MYC_22102868_ChIP-Seq_BL_Human1.35934544
47SPI1_23127762_ChIP-Seq_K562_Human1.35599853
48E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35483856
49KDM2B_26808549_Chip-Seq_JURKAT_Human1.35437731
50GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.33174257
51CTCF_27219007_Chip-Seq_ERYTHROID_Human1.32336138
52SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.31700530
53ZFP281_18757296_ChIP-ChIP_E14_Mouse1.29987957
54GATA2_21666600_ChIP-Seq_HMVEC_Human1.29561883
55DNAJC2_21179169_ChIP-ChIP_NT2_Human1.28816207
56* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.28637797
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27108168
58IKZF1_21737484_ChIP-ChIP_HCT116_Human1.26574218
59FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.25682144
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24790395
61RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.24766147
62GATA1_19941826_ChIP-Seq_K562_Human1.24207261
63SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.23165765
64BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23041299
65GATA1_22025678_ChIP-Seq_K562_Human1.22957727
66VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22208334
67TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.22168989
68IRF8_27001747_Chip-Seq_BMDM_Mouse1.22091497
69KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.21120121
70MAF_26560356_Chip-Seq_TH2_Human1.20936187
71SMC1_22415368_ChIP-Seq_MEFs_Mouse1.20826026
72SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.18929746
73SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.18929746
74BP1_19119308_ChIP-ChIP_Hs578T_Human1.18267192
75MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.18130391
76MYB_21317192_ChIP-Seq_ERMYB_Mouse1.17558750
77SA1_27219007_Chip-Seq_ERYTHROID_Human1.16723464
78PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16678791
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.15718356
80NCOR1_26117541_ChIP-Seq_K562_Human1.15684472
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.13806699
82STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13698559
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.13606738
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12816873
85MAF_26560356_Chip-Seq_TH1_Human1.12744808
86UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12346739
87GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12323409
88VDR_24763502_ChIP-Seq_THP-1_Human1.11543259
89STAT4_19710469_ChIP-ChIP_TH1__Mouse1.11421154
90PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11222938
91TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10670265
92FOXO3_23340844_ChIP-Seq_DLD1_Human1.10419595
93PPAR_26484153_Chip-Seq_NCI-H1993_Human1.09300709
94IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.08489809
95TET1_21451524_ChIP-Seq_MESCs_Mouse1.08314614
96ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.07812192
97BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07382561
98P63_26484246_Chip-Seq_KERATINOCYTES_Human1.07266487
99FOXA2_19822575_ChIP-Seq_HepG2_Human1.06305400
100ATF3_27146783_Chip-Seq_COLON_Human1.06271996
101ESR1_21235772_ChIP-Seq_MCF-7_Human1.05518189
102TBX20_22080862_ChIP-Seq_HEART_Mouse1.05442697
103TBX20_22328084_ChIP-Seq_HEART_Mouse1.05442697
104SOX9_24532713_ChIP-Seq_HFSC_Mouse1.05302529
105RARB_27405468_Chip-Seq_BRAIN_Mouse1.04096411
106FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.03668872
107CREB1_26743006_Chip-Seq_LNCaP_Human1.03064782
108HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.02966907
109IRF8_21731497_ChIP-ChIP_J774_Mouse1.02759529
110* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02740201
111ZFP281_27345836_Chip-Seq_ESCs_Mouse1.02113886
112TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01835926
113ERG_21242973_ChIP-ChIP_JURKAT_Human1.00208396
114MTF2_20144788_ChIP-Seq_MESCs_Mouse0.99999852
115GATA1_19941827_ChIP-Seq_MEL_Mouse0.99962471
116ZNF263_19887448_ChIP-Seq_K562_Human0.99059648
117HIF1A_21447827_ChIP-Seq_MCF-7_Human0.98906155
118UTX_26944678_Chip-Seq_JUKART_Human0.98593115
119KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98530555
120GATA2_19941826_ChIP-Seq_K562_Human0.97710784
121TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.96016440
122TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.95101260
123TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94977778
124SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94027906
125SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.93358595
126CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.93299964
127SMC4_20622854_ChIP-Seq_HELA_Human0.93281191
128P68_20966046_ChIP-Seq_HELA_Human0.93079638
129ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.92645819
130FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.92464254
131TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92431973
132EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.92140504
133* TP53_22127205_ChIP-Seq_IMR90_Human0.91811257

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.24472830
2MP0003705_abnormal_hypodermis_morpholog4.07110797
3MP0005275_abnormal_skin_tensile2.80733314
4MP0005058_abnormal_lysosome_morphology2.54752159
5MP0003279_aneurysm2.53090969
6MP0003300_gastrointestinal_ulcer2.49794149
7MP0003172_abnormal_lysosome_physiology2.32101302
8MP0001958_emphysema2.31193875
9MP0003303_peritoneal_inflammation2.22432910
10MP0009780_abnormal_chondrocyte_physiolo2.21623807
11MP0004859_abnormal_synaptic_plasticity2.14291251
12MP0003566_abnormal_cell_adhesion2.07716519
13MP0009840_abnormal_foam_cell2.07377598
14MP0000013_abnormal_adipose_tissue1.99592365
15MP0004858_abnormal_nervous_system1.97140346
16MP0005451_abnormal_body_composition1.96950437
17MP0003045_fibrosis1.95387835
18MP0005503_abnormal_tendon_morphology1.92054991
19MP0000569_abnormal_digit_pigmentation1.89769747
20MP0003191_abnormal_cellular_cholesterol1.84976629
21MP0008260_abnormal_autophagy1.83696051
22MP0010352_gastrointestinal_tract_polyps1.73024897
23MP0003091_abnormal_cell_migration1.71902245
24MP0004130_abnormal_muscle_cell1.66259805
25MP0000604_amyloidosis1.61254721
26MP0004510_myositis1.57843703
27MP0005360_urolithiasis1.57641611
28MP0004272_abnormal_basement_membrane1.54181149
29MP0006054_spinal_hemorrhage1.53960568
30MP0005083_abnormal_biliary_tract1.52718284
31MP0008961_abnormal_basal_metabolism1.52481962
32MP0005023_abnormal_wound_healing1.48390375
33MP0003075_altered_response_to1.47474235
34MP0003283_abnormal_digestive_organ1.43888090
35MP0003252_abnormal_bile_duct1.41508238
36MP0010234_abnormal_vibrissa_follicle1.41208688
37MP0001533_abnormal_skeleton_physiology1.41089198
38MP0003828_pulmonary_edema1.38700624
39MP0002139_abnormal_hepatobiliary_system1.37523120
40MP0010329_abnormal_lipoprotein_level1.34070970
41MP0005623_abnormal_meninges_morphology1.33954302
42MP0003329_amyloid_beta_deposits1.33479596
43MP0002877_abnormal_melanocyte_morpholog1.29768673
44MP0002998_abnormal_bone_remodeling1.27680538
45MP0002909_abnormal_adrenal_gland1.27650920
46MP0005365_abnormal_bile_salt1.26238699
47MP0003453_abnormal_keratinocyte_physiol1.26105850
48MP0003436_decreased_susceptibility_to1.25694917
49MP0000003_abnormal_adipose_tissue1.24303293
50MP0005670_abnormal_white_adipose1.22189222
51MP0004947_skin_inflammation1.20221674
52MP0005409_darkened_coat_color1.19909231
53MP0004185_abnormal_adipocyte_glucose1.19202515
54MP0005076_abnormal_cell_differentiation1.18678993
55MP0009278_abnormal_bone_marrow1.15823088
56MP0005375_adipose_tissue_phenotype1.15622289
57MP0005464_abnormal_platelet_physiology1.14157491
58MP0001835_abnormal_antigen_presentation1.13236389
59MP0002896_abnormal_bone_mineralization1.12622820
60MP0009384_cardiac_valve_regurgitation1.12314019
61MP0005257_abnormal_intraocular_pressure1.12169002
62MP0001915_intracranial_hemorrhage1.08066076
63MP0002060_abnormal_skin_morphology1.07202118
64MP0002168_other_aberrant_phenotype1.06111671
65MP0000751_myopathy1.04376529
66MP0001348_abnormal_lacrimal_gland1.04064933
67MP0002295_abnormal_pulmonary_circulatio1.04034853
68MP0002089_abnormal_postnatal_growth/wei1.03336510
69MP0005666_abnormal_adipose_tissue1.02764919
70MP0003183_abnormal_peptide_metabolism1.01227533
71MP0005000_abnormal_immune_tolerance1.01207704
72MP0005025_abnormal_response_to1.01055208
73MP0004808_abnormal_hematopoietic_stem1.00119642
74MP0000767_abnormal_smooth_muscle0.99680973
75MP0003763_abnormal_thymus_physiology0.99532043
76MP0002396_abnormal_hematopoietic_system0.95151544
77MP0003724_increased_susceptibility_to0.94188298
78MP0005167_abnormal_blood-brain_barrier0.93689763
79MP0000609_abnormal_liver_physiology0.93285617
80MP0000685_abnormal_immune_system0.91768168
81MP0002933_joint_inflammation0.91377693
82MP0005621_abnormal_cell_physiology0.89653589
83MP0010368_abnormal_lymphatic_system0.88498638
84MP0000747_muscle_weakness0.86233774
85MP0001243_abnormal_dermal_layer0.85553172
86MP0000733_abnormal_muscle_development0.85386192
87MP0002118_abnormal_lipid_homeostasis0.85280936
88MP0010155_abnormal_intestine_physiology0.84774340
89MP0002419_abnormal_innate_immunity0.84623108
90MP0003690_abnormal_glial_cell0.84572179
91MP0005390_skeleton_phenotype0.84173872
92MP0001849_ear_inflammation0.83383990
93MP0002166_altered_tumor_susceptibility0.83379763
94MP0001299_abnormal_eye_distance/0.80741079
95MP0005595_abnormal_vascular_smooth0.80218456
96MP0002405_respiratory_system_inflammati0.80033607
97MP0005166_decreased_susceptibility_to0.79128709
98MP0002452_abnormal_antigen_presenting0.79048560
99MP0003448_altered_tumor_morphology0.79044356
100MP0009333_abnormal_splenocyte_physiolog0.77613103
101MP0004883_abnormal_blood_vessel0.77396778
102MP0001614_abnormal_blood_vessel0.76490014
103MP0001851_eye_inflammation0.76111532
104MP0002420_abnormal_adaptive_immunity0.75996120
105MP0001819_abnormal_immune_cell0.75506461
106MP0005164_abnormal_response_to0.75096757
107MP0004233_abnormal_muscle_weight0.74439025
108MP0005165_increased_susceptibility_to0.74373278
109MP0009785_altered_susceptibility_to0.73549139
110MP0002254_reproductive_system_inflammat0.73038646
111MP0002723_abnormal_immune_serum0.71823885
112MP0000858_altered_metastatic_potential0.71624626
113MP0006082_CNS_inflammation0.70685034
114MP0003795_abnormal_bone_structure0.70527405
115MP0002113_abnormal_skeleton_development0.68892989
116MP0005085_abnormal_gallbladder_physiolo0.68842787
117MP0000249_abnormal_blood_vessel0.68159887
118MP0009053_abnormal_anal_canal0.67892193
119MP0002148_abnormal_hypersensitivity_rea0.67866954
120MP0001790_abnormal_immune_system0.67818510
121MP0005387_immune_system_phenotype0.67818510
122MP0001542_abnormal_bone_strength0.67580796
123MP0001216_abnormal_epidermal_layer0.66984124
124MP0002796_impaired_skin_barrier0.66905960
125MP0009931_abnormal_skin_appearance0.66875991
126MP0000759_abnormal_skeletal_muscle0.66703842
127MP0005584_abnormal_enzyme/coenzyme_acti0.66262714
128MP0010307_abnormal_tumor_latency0.65130953
129MP0009115_abnormal_fat_cell0.63779457
130MP0005508_abnormal_skeleton_morphology0.63653541
131MP0008874_decreased_physiological_sensi0.63368171
132MP0001501_abnormal_sleep_pattern0.62620468
133MP0000343_altered_response_to0.62516173
134MP0005448_abnormal_energy_balance0.60992527
135MP0004087_abnormal_muscle_fiber0.60432426
136MP0005319_abnormal_enzyme/_coenzyme0.60055210

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.98491367
2Premature rupture of membranes (HP:0001788)4.60898011
3Cerebral aneurysm (HP:0004944)4.24944938
4Peritonitis (HP:0002586)3.82670901
5Aortic dissection (HP:0002647)3.36268014
6Shallow orbits (HP:0000586)3.19058379
7Broad metatarsal (HP:0001783)3.17006499
8Dilatation of the ascending aorta (HP:0005111)3.14969599
9Aortic aneurysm (HP:0004942)3.14316568
10Mitral valve prolapse (HP:0001634)2.90761667
11Ankle contracture (HP:0006466)2.87213877
12Upper limb amyotrophy (HP:0009129)2.83870810
13Distal upper limb amyotrophy (HP:0007149)2.83870810
14Bladder diverticulum (HP:0000015)2.77154941
15Cervical subluxation (HP:0003308)2.75585206
16Deep venous thrombosis (HP:0002625)2.68677235
17Genu recurvatum (HP:0002816)2.66586318
18Atrophic scars (HP:0001075)2.64105072
19Aneurysm (HP:0002617)2.63759701
20Hand muscle atrophy (HP:0009130)2.51937274
21Dysostosis multiplex (HP:0000943)2.51138810
22Abnormality of dentin (HP:0010299)2.44527980
23Fragile skin (HP:0001030)2.42674703
24Broad face (HP:0000283)2.41987295
25Vertebral compression fractures (HP:0002953)2.40247076
26Mucopolysacchariduria (HP:0008155)2.39793145
27Urinary glycosaminoglycan excretion (HP:0003541)2.39793145
28Increased cerebral lipofuscin (HP:0011813)2.39569360
29Bowel diverticulosis (HP:0005222)2.37551614
30Follicular hyperkeratosis (HP:0007502)2.35072270
31Ectopia lentis (HP:0001083)2.34557804
32Long toe (HP:0010511)2.33178780
33Short nail (HP:0001799)2.31388683
34Striae distensae (HP:0001065)2.29988486
35Abnormality of mucopolysaccharide metabolism (HP:0011020)2.27012731
36Abnormality of polysaccharide metabolism (HP:0011012)2.27012731
37Abnormality of glycosaminoglycan metabolism (HP:0004371)2.27012731
38Mitral regurgitation (HP:0001653)2.25753940
39Turricephaly (HP:0000262)2.25636870
40Joint laxity (HP:0001388)2.24851689
41Blue sclerae (HP:0000592)2.23700669
42Myocardial infarction (HP:0001658)2.23499791
43Distal lower limb amyotrophy (HP:0008944)2.18561314
44Soft skin (HP:0000977)2.18134888
45Mitral stenosis (HP:0001718)2.11778074
46Vascular tortuosity (HP:0004948)2.11278096
47Ulnar bowing (HP:0003031)2.09443552
48Abnormality of glycolipid metabolism (HP:0010969)2.06416129
49Abnormality of liposaccharide metabolism (HP:0010968)2.06416129
50Abnormality of glycosphingolipid metabolism (HP:0004343)2.06416129
51Spinal cord lesions (HP:0100561)2.06349037
52Syringomyelia (HP:0003396)2.06349037
53Increased connective tissue (HP:0009025)2.05789834
54Type 1 muscle fiber predominance (HP:0003803)2.05068511
55Thin bony cortex (HP:0002753)2.05003981
56Xanthomatosis (HP:0000991)2.04565469
57Arterial tortuosity (HP:0005116)2.04531719
58Increased variability in muscle fiber diameter (HP:0003557)2.03318618
59Enlarged penis (HP:0000040)2.02581028
60Achilles tendon contracture (HP:0001771)2.01264649
61Abnormality of the Achilles tendon (HP:0005109)2.01185529
62Wormian bones (HP:0002645)1.99148937
63Cellulitis (HP:0100658)1.98576558
64Natal tooth (HP:0000695)1.98298307
65Hyperacusis (HP:0010780)1.97415183
66Biconcave vertebral bodies (HP:0004586)1.97382634
67Aortic regurgitation (HP:0001659)1.95503506
68Camptodactyly of toe (HP:0001836)1.93112647
69Radial bowing (HP:0002986)1.90955893
70Distal lower limb muscle weakness (HP:0009053)1.90032212
71Supranuclear gaze palsy (HP:0000605)1.89820270
72Eczematoid dermatitis (HP:0000976)1.89286688
73Flat acetabular roof (HP:0003180)1.88616093
74Hyperextensible skin (HP:0000974)1.88372742
75Complement deficiency (HP:0004431)1.88062050
76Frequent falls (HP:0002359)1.87244607
77Global brain atrophy (HP:0002283)1.84326398
78Emphysema (HP:0002097)1.83776663
79Hemiplegia (HP:0002301)1.83407254
80Generalized amyotrophy (HP:0003700)1.83349676
81Polygenic inheritance (HP:0010982)1.83237380
82Abnormality of the common coagulation pathway (HP:0010990)1.80901282
83Deviation of the hallux (HP:0010051)1.80853014
84Asymmetric septal hypertrophy (HP:0001670)1.80460849
85Nonimmune hydrops fetalis (HP:0001790)1.80457484
86Slender build (HP:0001533)1.80309571
87Spondylolisthesis (HP:0003302)1.79920366
88Abnormality of macrophages (HP:0004311)1.79758113
89Hematochezia (HP:0002573)1.79300645
90Increased density of long bones (HP:0006392)1.78345386
91Bowing of the arm (HP:0006488)1.78339220
92Bowed forearm bones (HP:0003956)1.78339220
93Abnormality of the peritoneum (HP:0002585)1.78096749
94Interstitial pulmonary disease (HP:0006530)1.77874074
95Lymphangioma (HP:0100764)1.77570510
96Joint stiffness (HP:0001387)1.76615338
97Systemic lupus erythematosus (HP:0002725)1.76052412
98Hallux valgus (HP:0001822)1.75913680
99Abnormality of the acetabulum (HP:0003170)1.74885022
100Premature skin wrinkling (HP:0100678)1.73722399
101Buphthalmos (HP:0000557)1.73644226
102Obstructive sleep apnea (HP:0002870)1.73076337
103Abnormality of skeletal muscle fiber size (HP:0012084)1.73021381
104Abnormality of oral frenula (HP:0000190)1.71615905
105Overgrowth (HP:0001548)1.71211923
106Abnormal delivery (HP:0001787)1.71173440
107Mildly elevated creatine phosphokinase (HP:0008180)1.69090308
108Spontaneous hematomas (HP:0007420)1.69029379
109Abnormality of the distal phalanges of the toes (HP:0010182)1.68850565
110Osteoarthritis (HP:0002758)1.68342553
111Loss of speech (HP:0002371)1.68121728
112Osteolytic defects of the hand bones (HP:0009699)1.67552250
113Osteolytic defects of the phalanges of the hand (HP:0009771)1.67552250
114Skin nodule (HP:0200036)1.66962252
115Abnormality of skull ossification (HP:0002703)1.66945700
116Absent frontal sinuses (HP:0002688)1.66723612
117Abnormal ossification of hand bones (HP:0005921)1.66332365
118Disproportionate tall stature (HP:0001519)1.66214476
119Macroorchidism (HP:0000053)1.65457775
120Long palpebral fissure (HP:0000637)1.64999885
121Elbow flexion contracture (HP:0002987)1.62470245
122Cupped ribs (HP:0000887)1.62457803
123J-shaped sella turcica (HP:0002680)1.62312505
124Infantile muscular hypotonia (HP:0008947)1.61778051
125Difficulty climbing stairs (HP:0003551)1.61597871
126Severe short stature (HP:0003510)1.60983003
127Increased neuronal autofluorescent lipopigment (HP:0002074)1.60876652
128Ovoid vertebral bodies (HP:0003300)1.60119622
129Coxa vara (HP:0002812)1.59138500
130Neonatal short-limb short stature (HP:0008921)1.57022953
131Spinal rigidity (HP:0003306)1.56810490
132Hypercortisolism (HP:0001578)1.55708965
133Abnormality of complement system (HP:0005339)1.55104575
134Congenital glaucoma (HP:0001087)1.54869735
135Hydroxyprolinuria (HP:0003080)1.54153264

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.04915849
2ERN13.57960287
3PKN23.49986136
4PRPF4B3.23607272
5SIK12.55349395
6TTN2.37900418
7SMG12.32478859
8RIPK12.27772106
9IRAK32.21554863
10PDGFRA2.11192596
11KSR21.90771253
12DDR21.89852454
13PTK61.84129568
14MAP3K91.75800193
15EEF2K1.70682987
16CAMKK11.59472001
17NTRK11.59073612
18MAP3K31.58847414
19CDK121.57654281
20SCYL21.56882001
21JAK11.52305410
22BMX1.50580167
23MAP3K101.50238108
24TAOK21.43580427
25MAP3K131.43128498
26PRKCH1.41712006
27PRKD31.40821704
28FGFR41.40239746
29TBK11.36761307
30EPHB11.35601006
31RET1.32355470
32LRRK21.32099636
33SIK21.32013530
34CAMK1D1.29413660
35TAOK11.27498519
36DAPK21.24875172
37RIPK41.24759786
38CAMK1G1.22715175
39PTK21.21719398
40MAP3K141.19987292
41TYK21.17439153
42PAK61.17056261
43TGFBR21.16093623
44EPHA21.15828523
45NTRK31.14749857
46MYLK1.12382089
47JAK31.11855401
48NEK91.09785088
49MAP3K21.08055812
50PIM21.04075968
51MAP3K61.02904642
52MAP4K11.02472222
53NME21.02071789
54TAOK31.01741456
55IRAK41.00422108
56KIT0.98961238
57EPHB20.94056263
58DMPK0.92111053
59FLT30.89459690
60GRK60.88178623
61TESK20.88097621
62JAK20.87637571
63ARAF0.86999497
64PTK2B0.86753808
65PDGFRB0.86662763
66PAK20.85858330
67MAP3K70.85757253
68MAP3K10.85355049
69LMTK20.81416353
70FES0.80800184
71EPHA30.79269895
72ALK0.78945080
73PDPK10.78362967
74LATS20.78143601
75TRPM70.76556062
76CAMKK20.75494085
77RPS6KC10.74719068
78RPS6KL10.74719068
79FGFR30.74467061
80INSRR0.73924381
81HCK0.73736156
82FER0.73651015
83MAP2K10.72303883
84PDK10.71968990
85MAP2K30.71950697
86PAK30.70036970
87MTOR0.67920277
88STK380.66748617
89ZAP700.66428011
90MET0.66036327
91MAPKAPK30.65801282
92PRKG20.64486373
93MAPK70.64061883
94RPS6KA20.63521654
95HIPK20.62444781
96MAPK110.61965813
97KDR0.60932246
98CSF1R0.60398619
99MOS0.59774889
100BTK0.59407024
101MAP3K80.58751118
102CDC42BPA0.58481743
103PAK40.57777776
104TNK20.55020919
105MINK10.54054476
106DAPK30.53245300
107KSR10.53193360
108IRAK20.51698377
109RPS6KA60.51449109
110DYRK1B0.51088480
111CDK60.50389210
112PRKD10.50156304
113BLK0.49785397
114TESK10.49292636
115MARK20.48793607
116SRC0.48195064
117ICK0.47624686
118FYN0.47383201
119MST1R0.45716462
120RAF10.45526529
121SGK30.44933011
122IKBKE0.44775677
123PRKD20.44563851
124MAPK120.44462619
125SIK30.44233037
126CDK50.43403586
127MAPKAPK20.42822905
128TYRO30.41782430
129ROCK20.41044469
130BCKDK0.40823166
131ABL20.40487737
132ROCK10.40006652
133EPHA40.38505015
134CHUK0.38242615
135FRK0.38144943
136EGFR0.37202589
137CSK0.37069898
138MAP3K110.36919896
139PIK3CG0.36249715

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.21285754
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.55130837
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.54430871
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.42546374
5Lysosome_Homo sapiens_hsa041421.40658721
6Arginine biosynthesis_Homo sapiens_hsa002201.37077309
7Focal adhesion_Homo sapiens_hsa045101.34824328
8ECM-receptor interaction_Homo sapiens_hsa045121.33292143
9Glycosaminoglycan degradation_Homo sapiens_hsa005311.31969742
10Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.28403986
11Complement and coagulation cascades_Homo sapiens_hsa046101.28365684
12Staphylococcus aureus infection_Homo sapiens_hsa051501.27698810
13Amoebiasis_Homo sapiens_hsa051461.24831257
14Notch signaling pathway_Homo sapiens_hsa043301.23826825
15Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.22332278
16Type II diabetes mellitus_Homo sapiens_hsa049301.21819467
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.21504300
18Glioma_Homo sapiens_hsa052141.21000184
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.20468708
20Hepatitis B_Homo sapiens_hsa051611.17507803
21Chronic myeloid leukemia_Homo sapiens_hsa052201.16654835
22Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.15182653
23Renal cell carcinoma_Homo sapiens_hsa052111.14347538
24Caffeine metabolism_Homo sapiens_hsa002321.13939989
25Primary bile acid biosynthesis_Homo sapiens_hsa001201.13119725
26Osteoclast differentiation_Homo sapiens_hsa043801.12822479
27Proteoglycans in cancer_Homo sapiens_hsa052051.12771824
28Insulin resistance_Homo sapiens_hsa049311.09416046
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.08886384
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06236940
31Bile secretion_Homo sapiens_hsa049761.05180089
32Apoptosis_Homo sapiens_hsa042101.04997012
33Hepatitis C_Homo sapiens_hsa051601.03604401
34Neurotrophin signaling pathway_Homo sapiens_hsa047221.02827230
35PPAR signaling pathway_Homo sapiens_hsa033201.01678406
36* Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.01066876
37Influenza A_Homo sapiens_hsa051641.00861771
38Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99653188
39mTOR signaling pathway_Homo sapiens_hsa041500.99258504
40NF-kappa B signaling pathway_Homo sapiens_hsa040640.95151319
41VEGF signaling pathway_Homo sapiens_hsa043700.94546763
42Bladder cancer_Homo sapiens_hsa052190.93992894
43Platelet activation_Homo sapiens_hsa046110.93949575
44Leishmaniasis_Homo sapiens_hsa051400.93550024
45Prostate cancer_Homo sapiens_hsa052150.92692395
46Thyroid cancer_Homo sapiens_hsa052160.92432369
47Measles_Homo sapiens_hsa051620.92117705
48Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91650874
49MicroRNAs in cancer_Homo sapiens_hsa052060.91188392
50Aldosterone synthesis and secretion_Homo sapiens_hsa049250.90394779
51Protein digestion and absorption_Homo sapiens_hsa049740.88726326
52Malaria_Homo sapiens_hsa051440.86219435
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.85554389
54Estrogen signaling pathway_Homo sapiens_hsa049150.85377518
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.85261314
56B cell receptor signaling pathway_Homo sapiens_hsa046620.85213202
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.85021972
58Pancreatic cancer_Homo sapiens_hsa052120.84793199
59Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84478561
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.84366800
61Synaptic vesicle cycle_Homo sapiens_hsa047210.82941348
62Non-small cell lung cancer_Homo sapiens_hsa052230.82726617
63Galactose metabolism_Homo sapiens_hsa000520.82265030
64Viral myocarditis_Homo sapiens_hsa054160.81193259
65ErbB signaling pathway_Homo sapiens_hsa040120.80197920
66Sphingolipid signaling pathway_Homo sapiens_hsa040710.80165363
67TNF signaling pathway_Homo sapiens_hsa046680.79813934
68Viral carcinogenesis_Homo sapiens_hsa052030.79425872
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.77085619
70Insulin signaling pathway_Homo sapiens_hsa049100.76677312
71Dilated cardiomyopathy_Homo sapiens_hsa054140.76639488
72Vibrio cholerae infection_Homo sapiens_hsa051100.76505283
73HTLV-I infection_Homo sapiens_hsa051660.76404183
74Toxoplasmosis_Homo sapiens_hsa051450.75963615
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.75926123
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.74857263
77Tuberculosis_Homo sapiens_hsa051520.74766989
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.74054990
79Pathways in cancer_Homo sapiens_hsa052000.73825068
80Adherens junction_Homo sapiens_hsa045200.73275287
81T cell receptor signaling pathway_Homo sapiens_hsa046600.73255243
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72779747
83Pentose phosphate pathway_Homo sapiens_hsa000300.72622121
84Prion diseases_Homo sapiens_hsa050200.72461076
85Colorectal cancer_Homo sapiens_hsa052100.72232073
86Leukocyte transendothelial migration_Homo sapiens_hsa046700.71075268
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.70785984
88Endocytosis_Homo sapiens_hsa041440.69735428
89N-Glycan biosynthesis_Homo sapiens_hsa005100.69604647
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.69499443
91Acute myeloid leukemia_Homo sapiens_hsa052210.69268121
92Fatty acid degradation_Homo sapiens_hsa000710.68051562
93Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.68009637
94GnRH signaling pathway_Homo sapiens_hsa049120.67856509
95Gastric acid secretion_Homo sapiens_hsa049710.67774252
96Pertussis_Homo sapiens_hsa051330.67194129
97Inositol phosphate metabolism_Homo sapiens_hsa005620.66621295
98Hematopoietic cell lineage_Homo sapiens_hsa046400.65792199
99Prolactin signaling pathway_Homo sapiens_hsa049170.65334416
100Toll-like receptor signaling pathway_Homo sapiens_hsa046200.64679705
101Insulin secretion_Homo sapiens_hsa049110.64582860
102Choline metabolism in cancer_Homo sapiens_hsa052310.64220264
103Salivary secretion_Homo sapiens_hsa049700.63823886
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62577917
105Other glycan degradation_Homo sapiens_hsa005110.62573633
106Lysine degradation_Homo sapiens_hsa003100.62071748
107Fructose and mannose metabolism_Homo sapiens_hsa000510.60882248
108Thyroid hormone synthesis_Homo sapiens_hsa049180.60616568
109Rap1 signaling pathway_Homo sapiens_hsa040150.60300702
110Shigellosis_Homo sapiens_hsa051310.60210136
111Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60065139
112Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59886308
113Oxytocin signaling pathway_Homo sapiens_hsa049210.59831466
114ABC transporters_Homo sapiens_hsa020100.59633770
115Melanoma_Homo sapiens_hsa052180.59491313
116Cocaine addiction_Homo sapiens_hsa050300.58920936
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58467978
118Endometrial cancer_Homo sapiens_hsa052130.57462707
119Phagosome_Homo sapiens_hsa041450.56833953
120Cholinergic synapse_Homo sapiens_hsa047250.56710312
121Fatty acid metabolism_Homo sapiens_hsa012120.56623569
122Small cell lung cancer_Homo sapiens_hsa052220.56489951
123NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56411442
124AMPK signaling pathway_Homo sapiens_hsa041520.56321854
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56065568
126Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55968443
127HIF-1 signaling pathway_Homo sapiens_hsa040660.55792374
128Long-term potentiation_Homo sapiens_hsa047200.55548258
129Chemokine signaling pathway_Homo sapiens_hsa040620.54293131
130Salmonella infection_Homo sapiens_hsa051320.53925699
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52988241
132Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51794015
133Olfactory transduction_Homo sapiens_hsa047400.51217091
134Tryptophan metabolism_Homo sapiens_hsa003800.50840505
135Circadian entrainment_Homo sapiens_hsa047130.50672076
136Glucagon signaling pathway_Homo sapiens_hsa049220.50478516
137cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50425466
1382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50258613

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