

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | behavioral response to nicotine (GO:0035095) | 6.34938132 |
| 2 | DNA deamination (GO:0045006) | 5.03346176 |
| 3 | rRNA methylation (GO:0031167) | 4.95398909 |
| 4 | indolalkylamine metabolic process (GO:0006586) | 4.81476692 |
| 5 | kynurenine metabolic process (GO:0070189) | 4.81232179 |
| 6 | indole-containing compound catabolic process (GO:0042436) | 4.60160846 |
| 7 | indolalkylamine catabolic process (GO:0046218) | 4.60160846 |
| 8 | tryptophan catabolic process (GO:0006569) | 4.60160846 |
| 9 | synaptic transmission, cholinergic (GO:0007271) | 4.44088186 |
| 10 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.40690097 |
| 11 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.40690097 |
| 12 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.40690097 |
| 13 | rRNA modification (GO:0000154) | 4.37232804 |
| 14 | protein K11-linked deubiquitination (GO:0035871) | 4.35979010 |
| 15 | piRNA metabolic process (GO:0034587) | 4.30337018 |
| 16 | activated T cell proliferation (GO:0050798) | 4.27639062 |
| 17 | tryptophan metabolic process (GO:0006568) | 4.22628679 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.15399667 |
| 19 | positive regulation of defense response to virus by host (GO:0002230) | 4.01900947 |
| 20 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.99071344 |
| 21 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.86285218 |
| 22 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.79002252 |
| 23 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.79002252 |
| 24 | intra-S DNA damage checkpoint (GO:0031573) | 3.73267489 |
| 25 | positive regulation of mRNA catabolic process (GO:0061014) | 3.72650901 |
| 26 | mannosylation (GO:0097502) | 3.65592129 |
| 27 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.62645025 |
| 28 | L-methionine salvage (GO:0071267) | 3.48969462 |
| 29 | L-methionine biosynthetic process (GO:0071265) | 3.48969462 |
| 30 | amino acid salvage (GO:0043102) | 3.48969462 |
| 31 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.47644856 |
| 32 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.47644856 |
| 33 | epithelial cilium movement (GO:0003351) | 3.44420810 |
| 34 | peptidyl-histidine modification (GO:0018202) | 3.38570331 |
| 35 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.37276756 |
| 36 | platelet dense granule organization (GO:0060155) | 3.31915290 |
| 37 | photoreceptor cell maintenance (GO:0045494) | 3.31663006 |
| 38 | somite development (GO:0061053) | 3.31550073 |
| 39 | negative regulation of mast cell activation (GO:0033004) | 3.29390321 |
| 40 | regulation of cilium movement (GO:0003352) | 3.24669115 |
| 41 | indole-containing compound metabolic process (GO:0042430) | 3.23622686 |
| 42 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.18284699 |
| 43 | methionine biosynthetic process (GO:0009086) | 3.16239530 |
| 44 | peroxisome fission (GO:0016559) | 3.13997370 |
| 45 | cytochrome complex assembly (GO:0017004) | 3.11632011 |
| 46 | head development (GO:0060322) | 3.07355633 |
| 47 | amine catabolic process (GO:0009310) | 3.06021016 |
| 48 | cellular biogenic amine catabolic process (GO:0042402) | 3.06021016 |
| 49 | reciprocal DNA recombination (GO:0035825) | 3.05396953 |
| 50 | reciprocal meiotic recombination (GO:0007131) | 3.05396953 |
| 51 | cellular response to interferon-beta (GO:0035458) | 3.04639334 |
| 52 | detection of light stimulus involved in visual perception (GO:0050908) | 3.03436867 |
| 53 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.03436867 |
| 54 | DNA methylation involved in gamete generation (GO:0043046) | 3.00017348 |
| 55 | regulation of defense response to virus by host (GO:0050691) | 2.99856609 |
| 56 | male meiosis I (GO:0007141) | 2.97485936 |
| 57 | S-adenosylmethionine metabolic process (GO:0046500) | 2.91779143 |
| 58 | regulation of mRNA catabolic process (GO:0061013) | 2.86605623 |
| 59 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.85199264 |
| 60 | transcription from mitochondrial promoter (GO:0006390) | 2.84859823 |
| 61 | protein complex biogenesis (GO:0070271) | 2.83635839 |
| 62 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.83571481 |
| 63 | regulation of gene silencing by miRNA (GO:0060964) | 2.83571481 |
| 64 | regulation of gene silencing by RNA (GO:0060966) | 2.83571481 |
| 65 | intraciliary transport (GO:0042073) | 2.83471043 |
| 66 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.82922382 |
| 67 | response to interferon-beta (GO:0035456) | 2.82014969 |
| 68 | protein-cofactor linkage (GO:0018065) | 2.80774055 |
| 69 | cellular response to exogenous dsRNA (GO:0071360) | 2.80141398 |
| 70 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.78485382 |
| 71 | acrosome assembly (GO:0001675) | 2.76697313 |
| 72 | GPI anchor metabolic process (GO:0006505) | 2.76319644 |
| 73 | respiratory chain complex IV assembly (GO:0008535) | 2.75509104 |
| 74 | endoderm formation (GO:0001706) | 2.75019454 |
| 75 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.74205408 |
| 76 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.74205408 |
| 77 | ATP synthesis coupled proton transport (GO:0015986) | 2.70220086 |
| 78 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.70220086 |
| 79 | positive regulation of protein homodimerization activity (GO:0090073) | 2.66827001 |
| 80 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.64860184 |
| 81 | transmission of nerve impulse (GO:0019226) | 2.62508834 |
| 82 | GPI anchor biosynthetic process (GO:0006506) | 2.61733057 |
| 83 | benzene-containing compound metabolic process (GO:0042537) | 2.60062578 |
| 84 | resolution of meiotic recombination intermediates (GO:0000712) | 2.59313848 |
| 85 | nonmotile primary cilium assembly (GO:0035058) | 2.59310893 |
| 86 | methionine metabolic process (GO:0006555) | 2.56115591 |
| 87 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.55397525 |
| 88 | cytidine deamination (GO:0009972) | 2.52000055 |
| 89 | cytidine metabolic process (GO:0046087) | 2.52000055 |
| 90 | cytidine catabolic process (GO:0006216) | 2.52000055 |
| 91 | positive regulation of antigen processing and presentation (GO:0002579) | 2.50785094 |
| 92 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.49871196 |
| 93 | sulfate transmembrane transport (GO:1902358) | 2.47391114 |
| 94 | brain morphogenesis (GO:0048854) | 2.46449094 |
| 95 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 2.45846042 |
| 96 | nephron tubule morphogenesis (GO:0072078) | 2.45322808 |
| 97 | nephron epithelium morphogenesis (GO:0072088) | 2.45322808 |
| 98 | cerebral cortex neuron differentiation (GO:0021895) | 2.45202286 |
| 99 | cilium morphogenesis (GO:0060271) | 2.44482782 |
| 100 | neuronal action potential (GO:0019228) | 2.43268712 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.91196001 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.44692770 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.42991693 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.69543901 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.53700252 |
| 6 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.34561193 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.33501599 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.21621289 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.17113177 |
| 10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.08807290 |
| 11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.03283231 |
| 12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.94869183 |
| 13 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.88147142 |
| 14 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.85891966 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81826938 |
| 16 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.77719492 |
| 17 | FUS_26573619_Chip-Seq_HEK293_Human | 1.69691548 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 1.65240090 |
| 19 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.65100747 |
| 20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.64837859 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.61968568 |
| 22 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.61810488 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.60971937 |
| 24 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.59524237 |
| 25 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.53761975 |
| 26 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.53761975 |
| 27 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.48795906 |
| 28 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.46718358 |
| 29 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.46534593 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.46492439 |
| 31 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.45390666 |
| 32 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.45207909 |
| 33 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.40733412 |
| 34 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39987540 |
| 35 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.39747617 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.37427192 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.37292831 |
| 38 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.35382158 |
| 39 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.34734518 |
| 40 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.34263615 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34056787 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34056787 |
| 43 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.33623779 |
| 44 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.32108646 |
| 45 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.32031335 |
| 46 | P300_19829295_ChIP-Seq_ESCs_Human | 1.30802278 |
| 47 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.27003784 |
| 48 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.25754157 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.25097215 |
| 50 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.24866009 |
| 51 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.24047493 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.23365729 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.22686989 |
| 54 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22570854 |
| 55 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.20479615 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.20194199 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.20194199 |
| 58 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19972640 |
| 59 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.19283835 |
| 60 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.19038678 |
| 61 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.17989317 |
| 62 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17959051 |
| 63 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.17277189 |
| 64 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.16502883 |
| 65 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16483467 |
| 66 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.16483467 |
| 67 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.16035404 |
| 68 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.15463623 |
| 69 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15440926 |
| 70 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.14950989 |
| 71 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14312290 |
| 72 | AR_20517297_ChIP-Seq_VCAP_Human | 1.14117214 |
| 73 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.13765985 |
| 74 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13749199 |
| 75 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.13546997 |
| 76 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13254141 |
| 77 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.13180129 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 1.11970113 |
| 79 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09785783 |
| 80 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09189811 |
| 81 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.08596513 |
| 82 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.08141731 |
| 83 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05744443 |
| 84 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.05046651 |
| 85 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.04670435 |
| 86 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04533280 |
| 87 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.03843876 |
| 88 | AR_25329375_ChIP-Seq_VCAP_Human | 1.03252323 |
| 89 | TCF4_23295773_ChIP-Seq_U87_Human | 1.03129918 |
| 90 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.02773801 |
| 91 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.02511139 |
| 92 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02121828 |
| 93 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.02054011 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.01566563 |
| 95 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.00972700 |
| 96 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.00966379 |
| 97 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.00556500 |
| 98 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.00433674 |
| 99 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.00297826 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.99361473 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 3.74133026 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.15837107 |
| 3 | MP0002638_abnormal_pupillary_reflex | 2.98494361 |
| 4 | MP0004885_abnormal_endolymph | 2.92421771 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 2.81786185 |
| 6 | MP0010386_abnormal_urinary_bladder | 2.73797745 |
| 7 | MP0005551_abnormal_eye_electrophysiolog | 2.51298962 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.35810154 |
| 9 | MP0000569_abnormal_digit_pigmentation | 2.30092952 |
| 10 | MP0006276_abnormal_autonomic_nervous | 2.18506266 |
| 11 | MP0008872_abnormal_physiological_respon | 2.16867175 |
| 12 | MP0004130_abnormal_muscle_cell | 2.06319842 |
| 13 | MP0001529_abnormal_vocalization | 2.01814413 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 1.98141860 |
| 15 | MP0003787_abnormal_imprinting | 1.96929490 |
| 16 | MP0005253_abnormal_eye_physiology | 1.89295912 |
| 17 | MP0000427_abnormal_hair_cycle | 1.78790675 |
| 18 | MP0002876_abnormal_thyroid_physiology | 1.78213935 |
| 19 | MP0004147_increased_porphyrin_level | 1.71813850 |
| 20 | MP0003879_abnormal_hair_cell | 1.65168285 |
| 21 | MP0001324_abnormal_eye_pigmentation | 1.62490005 |
| 22 | MP0003195_calcinosis | 1.60311814 |
| 23 | MP0000538_abnormal_urinary_bladder | 1.54421153 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.54354056 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.53759377 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.51811368 |
| 27 | MP0008775_abnormal_heart_ventricle | 1.50685245 |
| 28 | MP0004133_heterotaxia | 1.50537509 |
| 29 | MP0002736_abnormal_nociception_after | 1.49264443 |
| 30 | MP0001905_abnormal_dopamine_level | 1.48055833 |
| 31 | MP0004142_abnormal_muscle_tone | 1.46599212 |
| 32 | MP0003122_maternal_imprinting | 1.45905993 |
| 33 | MP0002938_white_spotting | 1.45483728 |
| 34 | MP0005386_behavior/neurological_phenoty | 1.42272187 |
| 35 | MP0004924_abnormal_behavior | 1.42272187 |
| 36 | MP0002735_abnormal_chemical_nociception | 1.42253638 |
| 37 | MP0009745_abnormal_behavioral_response | 1.38003614 |
| 38 | MP0002837_dystrophic_cardiac_calcinosis | 1.34187892 |
| 39 | MP0005174_abnormal_tail_pigmentation | 1.30822978 |
| 40 | MP0003011_delayed_dark_adaptation | 1.29821929 |
| 41 | MP0005195_abnormal_posterior_eye | 1.26772619 |
| 42 | MP0004215_abnormal_myocardial_fiber | 1.26766924 |
| 43 | MP0002752_abnormal_somatic_nervous | 1.25168865 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.23613478 |
| 45 | MP0000778_abnormal_nervous_system | 1.23312246 |
| 46 | MP0002928_abnormal_bile_duct | 1.23193492 |
| 47 | MP0004742_abnormal_vestibular_system | 1.22802740 |
| 48 | MP0009046_muscle_twitch | 1.21783549 |
| 49 | MP0005671_abnormal_response_to | 1.20387293 |
| 50 | MP0002572_abnormal_emotion/affect_behav | 1.19568316 |
| 51 | MP0003121_genomic_imprinting | 1.18546876 |
| 52 | MP0001270_distended_abdomen | 1.16343697 |
| 53 | MP0002272_abnormal_nervous_system | 1.13256051 |
| 54 | MP0002653_abnormal_ependyma_morphology | 1.12197660 |
| 55 | MP0005503_abnormal_tendon_morphology | 1.11431369 |
| 56 | MP0002102_abnormal_ear_morphology | 1.10978557 |
| 57 | MP0002557_abnormal_social/conspecific_i | 1.10250478 |
| 58 | MP0004270_analgesia | 1.10182935 |
| 59 | MP0001963_abnormal_hearing_physiology | 1.08802283 |
| 60 | MP0004145_abnormal_muscle_electrophysio | 1.03161250 |
| 61 | MP0005389_reproductive_system_phenotype | 1.02762010 |
| 62 | MP0001501_abnormal_sleep_pattern | 1.02648782 |
| 63 | MP0001440_abnormal_grooming_behavior | 1.02397004 |
| 64 | MP0002160_abnormal_reproductive_system | 1.01766195 |
| 65 | MP0000026_abnormal_inner_ear | 1.01657619 |
| 66 | MP0000015_abnormal_ear_pigmentation | 1.01480304 |
| 67 | MP0001485_abnormal_pinna_reflex | 0.99936860 |
| 68 | MP0001502_abnormal_circadian_rhythm | 0.98489406 |
| 69 | MP0000230_abnormal_systemic_arterial | 0.97824985 |
| 70 | MP0000372_irregular_coat_pigmentation | 0.97145929 |
| 71 | MP0004043_abnormal_pH_regulation | 0.96451326 |
| 72 | MP0002138_abnormal_hepatobiliary_system | 0.95923979 |
| 73 | MP0009764_decreased_sensitivity_to | 0.92760808 |
| 74 | MP0003878_abnormal_ear_physiology | 0.90710920 |
| 75 | MP0005377_hearing/vestibular/ear_phenot | 0.90710920 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.90462532 |
| 77 | MP0001764_abnormal_homeostasis | 0.90363389 |
| 78 | MP0005646_abnormal_pituitary_gland | 0.88979943 |
| 79 | MP0001835_abnormal_antigen_presentation | 0.88460940 |
| 80 | MP0001984_abnormal_olfaction | 0.87049989 |
| 81 | MP0003635_abnormal_synaptic_transmissio | 0.85485605 |
| 82 | MP0005332_abnormal_amino_acid | 0.84512412 |
| 83 | MP0006054_spinal_hemorrhage | 0.84369470 |
| 84 | MP0002063_abnormal_learning/memory/cond | 0.82558375 |
| 85 | MP0001800_abnormal_humoral_immune | 0.81906455 |
| 86 | MP0002277_abnormal_respiratory_mucosa | 0.81242034 |
| 87 | MP0002184_abnormal_innervation | 0.79970330 |
| 88 | MP0002229_neurodegeneration | 0.79334461 |
| 89 | MP0001919_abnormal_reproductive_system | 0.79235880 |
| 90 | MP0002733_abnormal_thermal_nociception | 0.79031695 |
| 91 | MP0009115_abnormal_fat_cell | 0.78476504 |
| 92 | MP0004264_abnormal_extraembryonic_tissu | 0.78332048 |
| 93 | MP0002282_abnormal_trachea_morphology | 0.78133024 |
| 94 | MP0003698_abnormal_male_reproductive | 0.77797490 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.77613529 |
| 96 | MP0001970_abnormal_pain_threshold | 0.76813250 |
| 97 | MP0002095_abnormal_skin_pigmentation | 0.75991682 |
| 98 | MP0002067_abnormal_sensory_capabilities | 0.74815767 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.74269252 |
| 100 | MP0002210_abnormal_sex_determination | 0.74214782 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic fibrosis (HP:0100732) | 4.39469596 |
| 2 | Pancreatic cysts (HP:0001737) | 4.08105000 |
| 3 | Abnormality of midbrain morphology (HP:0002418) | 3.81830240 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 3.81830240 |
| 5 | Chronic hepatic failure (HP:0100626) | 3.60502704 |
| 6 | True hermaphroditism (HP:0010459) | 3.55763937 |
| 7 | Type II lissencephaly (HP:0007260) | 3.51722627 |
| 8 | Papilledema (HP:0001085) | 3.35236638 |
| 9 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.24916735 |
| 10 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.24916735 |
| 11 | Medial flaring of the eyebrow (HP:0010747) | 3.20515819 |
| 12 | Nephronophthisis (HP:0000090) | 3.14893608 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.13729982 |
| 14 | Abnormality of the renal medulla (HP:0100957) | 3.11556595 |
| 15 | Gait imbalance (HP:0002141) | 2.93417111 |
| 16 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.92944497 |
| 17 | Decreased central vision (HP:0007663) | 2.80748934 |
| 18 | Congenital primary aphakia (HP:0007707) | 2.76502606 |
| 19 | Nephrogenic diabetes insipidus (HP:0009806) | 2.72021573 |
| 20 | Abnormality of the renal cortex (HP:0011035) | 2.71813527 |
| 21 | Bile duct proliferation (HP:0001408) | 2.69514140 |
| 22 | Abnormal biliary tract physiology (HP:0012439) | 2.69514140 |
| 23 | Cystic liver disease (HP:0006706) | 2.64420860 |
| 24 | Abolished electroretinogram (ERG) (HP:0000550) | 2.61352917 |
| 25 | Progressive inability to walk (HP:0002505) | 2.57151877 |
| 26 | Increased corneal curvature (HP:0100692) | 2.55320446 |
| 27 | Keratoconus (HP:0000563) | 2.55320446 |
| 28 | Abnormality of the corticospinal tract (HP:0002492) | 2.47554905 |
| 29 | Attenuation of retinal blood vessels (HP:0007843) | 2.44948030 |
| 30 | Concave nail (HP:0001598) | 2.44188942 |
| 31 | Hepatocellular necrosis (HP:0001404) | 2.43281047 |
| 32 | Hepatic necrosis (HP:0002605) | 2.40267948 |
| 33 | Abnormal drinking behavior (HP:0030082) | 2.36008295 |
| 34 | Polydipsia (HP:0001959) | 2.36008295 |
| 35 | Inability to walk (HP:0002540) | 2.33743363 |
| 36 | Chronic sinusitis (HP:0011109) | 2.29752192 |
| 37 | Albinism (HP:0001022) | 2.27783717 |
| 38 | Hyperventilation (HP:0002883) | 2.24659344 |
| 39 | Alveolar cell carcinoma (HP:0006519) | 2.23555587 |
| 40 | Genital tract atresia (HP:0001827) | 2.22784611 |
| 41 | Macular degeneration (HP:0000608) | 2.22254790 |
| 42 | Renal cortical cysts (HP:0000803) | 2.22205379 |
| 43 | Polyphagia (HP:0002591) | 2.17708466 |
| 44 | Sclerocornea (HP:0000647) | 2.14778556 |
| 45 | Abnormality of the pons (HP:0007361) | 2.13895422 |
| 46 | Congenital hepatic fibrosis (HP:0002612) | 2.12910028 |
| 47 | Cerebellar dysplasia (HP:0007033) | 2.12682865 |
| 48 | Methylmalonic aciduria (HP:0012120) | 2.12142757 |
| 49 | Vaginal atresia (HP:0000148) | 2.09358576 |
| 50 | Polyuria (HP:0000103) | 2.09094246 |
| 51 | Hyperglycinemia (HP:0002154) | 2.07768641 |
| 52 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.06912085 |
| 53 | 3-Methylglutaconic aciduria (HP:0003535) | 2.05417856 |
| 54 | Increased CSF lactate (HP:0002490) | 2.04664458 |
| 55 | Gaze-evoked nystagmus (HP:0000640) | 2.03668939 |
| 56 | Hypoplasia of the pons (HP:0012110) | 2.02111421 |
| 57 | Anterior segment dysgenesis (HP:0007700) | 2.01980555 |
| 58 | Lipid accumulation in hepatocytes (HP:0006561) | 2.01169880 |
| 59 | Poor coordination (HP:0002370) | 2.01167586 |
| 60 | Mitochondrial inheritance (HP:0001427) | 2.00913189 |
| 61 | Furrowed tongue (HP:0000221) | 1.98838633 |
| 62 | Agitation (HP:0000713) | 1.95896887 |
| 63 | Hemiparesis (HP:0001269) | 1.95289462 |
| 64 | Focal seizures (HP:0007359) | 1.95089761 |
| 65 | Thyroiditis (HP:0100646) | 1.94614046 |
| 66 | Ketosis (HP:0001946) | 1.93148470 |
| 67 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.92697097 |
| 68 | Absent/shortened dynein arms (HP:0200106) | 1.92697097 |
| 69 | Severe muscular hypotonia (HP:0006829) | 1.91350881 |
| 70 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.90557037 |
| 71 | Anencephaly (HP:0002323) | 1.87599664 |
| 72 | Methylmalonic acidemia (HP:0002912) | 1.86365459 |
| 73 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.86265112 |
| 74 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.85493730 |
| 75 | Severe combined immunodeficiency (HP:0004430) | 1.85259897 |
| 76 | Abnormality of the vertebral endplates (HP:0005106) | 1.84199008 |
| 77 | Lissencephaly (HP:0001339) | 1.83048526 |
| 78 | Hypoplasia of the uterus (HP:0000013) | 1.82867875 |
| 79 | Cone-rod dystrophy (HP:0000548) | 1.81675835 |
| 80 | Large for gestational age (HP:0001520) | 1.81199310 |
| 81 | Bulbous nose (HP:0000414) | 1.78440735 |
| 82 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.77920525 |
| 83 | Small hand (HP:0200055) | 1.77051248 |
| 84 | Febrile seizures (HP:0002373) | 1.76723051 |
| 85 | Tubular atrophy (HP:0000092) | 1.76554749 |
| 86 | Type I transferrin isoform profile (HP:0003642) | 1.76529680 |
| 87 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75911842 |
| 88 | Genetic anticipation (HP:0003743) | 1.75555153 |
| 89 | Type 2 muscle fiber atrophy (HP:0003554) | 1.74630114 |
| 90 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.74515626 |
| 91 | Pachygyria (HP:0001302) | 1.74323914 |
| 92 | CNS demyelination (HP:0007305) | 1.72373789 |
| 93 | Postaxial foot polydactyly (HP:0001830) | 1.70794078 |
| 94 | Cerebral hypomyelination (HP:0006808) | 1.70542753 |
| 95 | Optic disc pallor (HP:0000543) | 1.68677157 |
| 96 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.68658786 |
| 97 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.67996568 |
| 98 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.67996568 |
| 99 | Occipital encephalocele (HP:0002085) | 1.67915731 |
| 100 | IgG deficiency (HP:0004315) | 1.67626701 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 6.49315739 |
| 2 | NUAK1 | 3.52177765 |
| 3 | FRK | 3.08856398 |
| 4 | VRK1 | 2.75866792 |
| 5 | SIK3 | 2.49163068 |
| 6 | TAF1 | 2.23767095 |
| 7 | TNIK | 2.23420788 |
| 8 | DYRK1B | 2.18951980 |
| 9 | TRIM28 | 2.15169662 |
| 10 | WNK4 | 2.10359438 |
| 11 | KIT | 2.09978768 |
| 12 | MAPK13 | 1.90341609 |
| 13 | CAMKK2 | 1.77536626 |
| 14 | OXSR1 | 1.68795810 |
| 15 | EIF2AK3 | 1.63111593 |
| 16 | AKT3 | 1.56049834 |
| 17 | STK16 | 1.49724281 |
| 18 | CDK3 | 1.47310913 |
| 19 | TLK1 | 1.45043153 |
| 20 | GRK1 | 1.40497364 |
| 21 | PIM2 | 1.38570448 |
| 22 | EPHB2 | 1.36629467 |
| 23 | MAP4K2 | 1.36219180 |
| 24 | PINK1 | 1.35986438 |
| 25 | FLT3 | 1.28677066 |
| 26 | PNCK | 1.23959331 |
| 27 | PIK3CA | 1.21299355 |
| 28 | NTRK2 | 1.21175188 |
| 29 | ADRBK2 | 1.19402268 |
| 30 | MAP2K6 | 1.18544679 |
| 31 | PHKG2 | 1.18431637 |
| 32 | PHKG1 | 1.18431637 |
| 33 | CDK19 | 1.17186626 |
| 34 | RIPK1 | 1.14178169 |
| 35 | VRK2 | 1.14044368 |
| 36 | STK39 | 1.12981227 |
| 37 | ACVR1B | 1.11856098 |
| 38 | WNK3 | 1.10047901 |
| 39 | TRPM7 | 1.06835934 |
| 40 | BCR | 1.02040693 |
| 41 | MAPK15 | 1.01112076 |
| 42 | TYK2 | 0.99926040 |
| 43 | IKBKB | 0.96993782 |
| 44 | IKBKE | 0.89668319 |
| 45 | SIK2 | 0.87205219 |
| 46 | NTRK1 | 0.86755527 |
| 47 | MUSK | 0.85968930 |
| 48 | BMPR1B | 0.85829131 |
| 49 | TXK | 0.85818674 |
| 50 | NME1 | 0.84833019 |
| 51 | MAPK11 | 0.83594647 |
| 52 | PLK3 | 0.78935728 |
| 53 | MAPKAPK5 | 0.76030961 |
| 54 | PRKCQ | 0.75970945 |
| 55 | PRKG2 | 0.74606692 |
| 56 | MAP3K6 | 0.73863743 |
| 57 | STK11 | 0.73253864 |
| 58 | PAK3 | 0.72852146 |
| 59 | PRKCE | 0.71732286 |
| 60 | ABL2 | 0.66891515 |
| 61 | PRKAA1 | 0.66524327 |
| 62 | EIF2AK1 | 0.63982972 |
| 63 | DYRK1A | 0.63394701 |
| 64 | ADRBK1 | 0.62347158 |
| 65 | MAP3K14 | 0.62090379 |
| 66 | FES | 0.61884301 |
| 67 | MARK3 | 0.57079364 |
| 68 | CAMK1 | 0.56481150 |
| 69 | CHUK | 0.55297146 |
| 70 | NTRK3 | 0.53873235 |
| 71 | ZAK | 0.53504885 |
| 72 | ILK | 0.52612001 |
| 73 | PKN1 | 0.51697810 |
| 74 | TYRO3 | 0.50754040 |
| 75 | JAK3 | 0.50686492 |
| 76 | IRAK4 | 0.49738670 |
| 77 | BCKDK | 0.49589022 |
| 78 | MARK1 | 0.48507381 |
| 79 | MAP2K7 | 0.47358434 |
| 80 | ABL1 | 0.45747350 |
| 81 | MARK2 | 0.45279116 |
| 82 | TNK2 | 0.45275145 |
| 83 | MAP3K11 | 0.45064791 |
| 84 | PIK3CG | 0.44603152 |
| 85 | PKN2 | 0.43358453 |
| 86 | MAPKAPK3 | 0.42484789 |
| 87 | PRKG1 | 0.40856732 |
| 88 | CAMKK1 | 0.40522309 |
| 89 | PRKCZ | 0.39429645 |
| 90 | PIM1 | 0.38878498 |
| 91 | IGF1R | 0.37368360 |
| 92 | DYRK2 | 0.36171945 |
| 93 | NEK1 | 0.33866647 |
| 94 | MAP3K4 | 0.33406618 |
| 95 | PRKACA | 0.33069694 |
| 96 | MAPK7 | 0.32475600 |
| 97 | CASK | 0.31773226 |
| 98 | CSNK1A1 | 0.30519099 |
| 99 | PRKD2 | 0.30344452 |
| 100 | BTK | 0.28018021 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.17892432 |
| 2 | Tryptophan metabolism_Homo sapiens_hsa00380 | 3.06215670 |
| 3 | Basal transcription factors_Homo sapiens_hsa03022 | 2.73030802 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.68680276 |
| 5 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.52970700 |
| 6 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.48438802 |
| 7 | Phototransduction_Homo sapiens_hsa04744 | 2.26730647 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.26241788 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.17380879 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.13999672 |
| 11 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.98976488 |
| 12 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.93047982 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.90857706 |
| 14 | Peroxisome_Homo sapiens_hsa04146 | 1.80334827 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.73339780 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.70523160 |
| 17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.64078444 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.62231465 |
| 19 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.61570015 |
| 20 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.54746110 |
| 21 | Proteasome_Homo sapiens_hsa03050 | 1.45648558 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.44808398 |
| 23 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.39557597 |
| 24 | Protein export_Homo sapiens_hsa03060 | 1.35147630 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31590926 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.30175637 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30141788 |
| 28 | RNA polymerase_Homo sapiens_hsa03020 | 1.29583171 |
| 29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.28672155 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25522062 |
| 31 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.25299224 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.24509875 |
| 33 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.23838695 |
| 34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.23371785 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.21997293 |
| 36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20747844 |
| 37 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.19445668 |
| 38 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.18264277 |
| 39 | ABC transporters_Homo sapiens_hsa02010 | 1.18251628 |
| 40 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.17107180 |
| 41 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.07572248 |
| 42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.07479173 |
| 43 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.06182282 |
| 44 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.04648787 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.04069164 |
| 46 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.01084859 |
| 47 | Insulin secretion_Homo sapiens_hsa04911 | 0.98921319 |
| 48 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.98901169 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.96435498 |
| 50 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.95921838 |
| 51 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.92778325 |
| 52 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92129160 |
| 53 | Ribosome_Homo sapiens_hsa03010 | 0.89839315 |
| 54 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87875619 |
| 55 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.86642070 |
| 56 | Taste transduction_Homo sapiens_hsa04742 | 0.85576917 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.84784307 |
| 58 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.84455723 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80657342 |
| 60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78552222 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.78550407 |
| 62 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.77852782 |
| 63 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.77581028 |
| 64 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.76906335 |
| 65 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.76081845 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72072433 |
| 67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.70609404 |
| 68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.70294406 |
| 69 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.69904959 |
| 70 | Purine metabolism_Homo sapiens_hsa00230 | 0.68204237 |
| 71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66949781 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64348866 |
| 73 | Histidine metabolism_Homo sapiens_hsa00340 | 0.60104304 |
| 74 | Cocaine addiction_Homo sapiens_hsa05030 | 0.60030066 |
| 75 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.56422668 |
| 76 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.55604724 |
| 77 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.50993505 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50903037 |
| 79 | Sulfur relay system_Homo sapiens_hsa04122 | 0.50652465 |
| 80 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.50194881 |
| 81 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.48611329 |
| 82 | Salivary secretion_Homo sapiens_hsa04970 | 0.44728911 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43226962 |
| 84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41800759 |
| 85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.39377404 |
| 86 | Melanoma_Homo sapiens_hsa05218 | 0.39318105 |
| 87 | Morphine addiction_Homo sapiens_hsa05032 | 0.35628161 |
| 88 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.35063777 |
| 89 | Lysine degradation_Homo sapiens_hsa00310 | 0.34758416 |
| 90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34380723 |
| 91 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.34177549 |
| 92 | Mineral absorption_Homo sapiens_hsa04978 | 0.33998545 |
| 93 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.33932568 |
| 94 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.33652898 |
| 95 | Renin secretion_Homo sapiens_hsa04924 | 0.33573793 |
| 96 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.32238818 |
| 97 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.32143612 |
| 98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.31362322 |
| 99 | RNA transport_Homo sapiens_hsa03013 | 0.29731748 |
| 100 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.29561741 |

