

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neuronal action potential propagation (GO:0019227) | 8.85532313 |
| 2 | gamma-aminobutyric acid transport (GO:0015812) | 8.63782411 |
| 3 | positive regulation of action potential (GO:0045760) | 8.01792656 |
| 4 | detection of light stimulus involved in sensory perception (GO:0050962) | 7.00709031 |
| 5 | detection of light stimulus involved in visual perception (GO:0050908) | 7.00709031 |
| 6 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 6.32199575 |
| 7 | fusion of sperm to egg plasma membrane (GO:0007342) | 6.01689361 |
| 8 | neuronal action potential (GO:0019228) | 5.98930985 |
| 9 | histone H4-K12 acetylation (GO:0043983) | 5.73836352 |
| 10 | nucleoside transmembrane transport (GO:1901642) | 5.64082844 |
| 11 | serotonin metabolic process (GO:0042428) | 5.57743641 |
| 12 | primary amino compound metabolic process (GO:1901160) | 5.49464681 |
| 13 | Peyers patch development (GO:0048541) | 5.36163127 |
| 14 | mucosal-associated lymphoid tissue development (GO:0048537) | 5.36163127 |
| 15 | behavioral response to nicotine (GO:0035095) | 5.05407791 |
| 16 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 5.01187987 |
| 17 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.96714960 |
| 18 | regulation of acrosome reaction (GO:0060046) | 4.77537125 |
| 19 | regulation of chromatin binding (GO:0035561) | 4.73302627 |
| 20 | regulation of gene silencing by RNA (GO:0060966) | 4.55682757 |
| 21 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.55682757 |
| 22 | regulation of gene silencing by miRNA (GO:0060964) | 4.55682757 |
| 23 | cellular ketone body metabolic process (GO:0046950) | 4.49936438 |
| 24 | regulation of action potential (GO:0098900) | 4.44367465 |
| 25 | plasma membrane fusion (GO:0045026) | 4.27909243 |
| 26 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.92112441 |
| 27 | nucleoside transport (GO:0015858) | 3.92056901 |
| 28 | ketone body metabolic process (GO:1902224) | 3.91942215 |
| 29 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 3.91887595 |
| 30 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 3.91344207 |
| 31 | protein-chromophore linkage (GO:0018298) | 3.80024902 |
| 32 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.79621396 |
| 33 | spinal cord motor neuron differentiation (GO:0021522) | 3.70455625 |
| 34 | NLS-bearing protein import into nucleus (GO:0006607) | 3.70206131 |
| 35 | neuromuscular junction development (GO:0007528) | 3.68690906 |
| 36 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.67390419 |
| 37 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.67005296 |
| 38 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.60817588 |
| 39 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.54753259 |
| 40 | behavioral response to ethanol (GO:0048149) | 3.53858785 |
| 41 | keratinocyte development (GO:0003334) | 3.50394420 |
| 42 | indole-containing compound metabolic process (GO:0042430) | 3.48109666 |
| 43 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.47768928 |
| 44 | outflow tract septum morphogenesis (GO:0003148) | 3.41043734 |
| 45 | response to acidic pH (GO:0010447) | 3.34696927 |
| 46 | positive regulation of mRNA catabolic process (GO:0061014) | 3.30788569 |
| 47 | striatum development (GO:0021756) | 3.28666632 |
| 48 | regulation of female gonad development (GO:2000194) | 3.24880585 |
| 49 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.23509344 |
| 50 | seminiferous tubule development (GO:0072520) | 3.17018746 |
| 51 | multicellular organism reproduction (GO:0032504) | 3.15647871 |
| 52 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.07938981 |
| 53 | maturation of 5.8S rRNA (GO:0000460) | 3.05874012 |
| 54 | striated muscle atrophy (GO:0014891) | 3.05630908 |
| 55 | action potential (GO:0001508) | 3.03166027 |
| 56 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.02415963 |
| 57 | transepithelial transport (GO:0070633) | 2.99777397 |
| 58 | opioid receptor signaling pathway (GO:0038003) | 2.98773137 |
| 59 | histone-serine phosphorylation (GO:0035404) | 2.96572847 |
| 60 | synaptic transmission, glutamatergic (GO:0035249) | 2.95988572 |
| 61 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.94215098 |
| 62 | circadian sleep/wake cycle process (GO:0022410) | 2.92226376 |
| 63 | motile cilium assembly (GO:0044458) | 2.91142019 |
| 64 | male meiosis (GO:0007140) | 2.90418760 |
| 65 | establishment of tissue polarity (GO:0007164) | 2.90024677 |
| 66 | establishment of planar polarity (GO:0001736) | 2.90024677 |
| 67 | regulation of mRNA catabolic process (GO:0061013) | 2.89150960 |
| 68 | regulation of histone phosphorylation (GO:0033127) | 2.89149040 |
| 69 | cornea development in camera-type eye (GO:0061303) | 2.87943017 |
| 70 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.87084641 |
| 71 | epithelial cilium movement (GO:0003351) | 2.86608802 |
| 72 | regulation of Rab GTPase activity (GO:0032313) | 2.83204487 |
| 73 | positive regulation of Rab GTPase activity (GO:0032851) | 2.83204487 |
| 74 | ventricular septum development (GO:0003281) | 2.82003009 |
| 75 | regulation of sensory perception of pain (GO:0051930) | 2.81619570 |
| 76 | regulation of sensory perception (GO:0051931) | 2.81619570 |
| 77 | protein import into peroxisome matrix (GO:0016558) | 2.81035984 |
| 78 | interkinetic nuclear migration (GO:0022027) | 2.80911237 |
| 79 | thymus development (GO:0048538) | 2.76669253 |
| 80 | cardiac septum development (GO:0003279) | 2.74530590 |
| 81 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.73540148 |
| 82 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.71438083 |
| 83 | connective tissue development (GO:0061448) | 2.70338657 |
| 84 | sensory perception of taste (GO:0050909) | 2.68759875 |
| 85 | long-term memory (GO:0007616) | 2.65649587 |
| 86 | negative regulation of TOR signaling (GO:0032007) | 2.64678039 |
| 87 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.64299420 |
| 88 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.64299420 |
| 89 | skeletal muscle adaptation (GO:0043501) | 2.64287764 |
| 90 | tryptophan catabolic process (GO:0006569) | 2.63614778 |
| 91 | indole-containing compound catabolic process (GO:0042436) | 2.63614778 |
| 92 | indolalkylamine catabolic process (GO:0046218) | 2.63614778 |
| 93 | Sertoli cell development (GO:0060009) | 2.63298228 |
| 94 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.62382910 |
| 95 | DNA methylation involved in gamete generation (GO:0043046) | 2.61521761 |
| 96 | positive regulation of protein kinase C signaling (GO:0090037) | 2.60283245 |
| 97 | neuron remodeling (GO:0016322) | 2.60217126 |
| 98 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.60117658 |
| 99 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.57502385 |
| 100 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.56953357 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 8.93796931 |
| 2 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 5.18506541 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.49249847 |
| 4 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.32345418 |
| 5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.00168577 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.79845441 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.36083969 |
| 8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.28815180 |
| 9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.20107411 |
| 10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.01904453 |
| 11 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.78691413 |
| 12 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.63703948 |
| 13 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.63360284 |
| 14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.59387533 |
| 15 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.57772486 |
| 16 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.56517432 |
| 17 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.51265079 |
| 18 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47761798 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47482381 |
| 20 | ERA_21632823_ChIP-Seq_H3396_Human | 1.43719093 |
| 21 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.41165533 |
| 22 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.38921564 |
| 23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.36924852 |
| 24 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.34762451 |
| 25 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.34610972 |
| 26 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.33261830 |
| 27 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.33079033 |
| 28 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.31218768 |
| 29 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.30658853 |
| 30 | AR_25329375_ChIP-Seq_VCAP_Human | 1.26862554 |
| 31 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24357199 |
| 32 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24357199 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.22201013 |
| 34 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.21452271 |
| 35 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.21058600 |
| 36 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.20458700 |
| 37 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.17654401 |
| 38 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.17169444 |
| 39 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.16578567 |
| 40 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16538655 |
| 41 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.15707044 |
| 42 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.15203210 |
| 43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.12234294 |
| 44 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.11939464 |
| 45 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.11707840 |
| 46 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.10532003 |
| 47 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.10149553 |
| 48 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.09922917 |
| 49 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.09659897 |
| 50 | STAT3_23295773_ChIP-Seq_U87_Human | 1.07249163 |
| 51 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.05347588 |
| 52 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.05347588 |
| 53 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.04644915 |
| 54 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03441569 |
| 55 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.02788164 |
| 56 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.02637240 |
| 57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.01989454 |
| 58 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.00233759 |
| 59 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99875633 |
| 60 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99487312 |
| 61 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.98367061 |
| 62 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.98141506 |
| 63 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.95480636 |
| 64 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.95302857 |
| 65 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.95200481 |
| 66 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.93713127 |
| 67 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.93239877 |
| 68 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.92008708 |
| 69 | TCF4_23295773_ChIP-Seq_U87_Human | 0.91809704 |
| 70 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.91318372 |
| 71 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.91012749 |
| 72 | KDM2B_26808549_Chip-Seq_REH_Human | 0.90647930 |
| 73 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90579668 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 0.90301434 |
| 75 | P300_19829295_ChIP-Seq_ESCs_Human | 0.88079200 |
| 76 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.87877744 |
| 77 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87706916 |
| 78 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.87469591 |
| 79 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.87332978 |
| 80 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.86881630 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.86450746 |
| 82 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.86371834 |
| 83 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.85339992 |
| 84 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.84966034 |
| 85 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 0.84699325 |
| 86 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.84356118 |
| 87 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.83926694 |
| 88 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.83664673 |
| 89 | FUS_26573619_Chip-Seq_HEK293_Human | 0.83662011 |
| 90 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.83652113 |
| 91 | P68_20966046_ChIP-Seq_HELA_Human | 0.83395816 |
| 92 | TP53_16413492_ChIP-PET_HCT116_Human | 0.82827753 |
| 93 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.82602266 |
| 94 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.82449328 |
| 95 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.81964957 |
| 96 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.81907932 |
| 97 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.81391820 |
| 98 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.81054611 |
| 99 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.79890941 |
| 100 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.79533871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010030_abnormal_orbit_morphology | 5.31468532 |
| 2 | MP0003136_yellow_coat_color | 4.63948581 |
| 3 | MP0005174_abnormal_tail_pigmentation | 2.91767217 |
| 4 | MP0005423_abnormal_somatic_nervous | 2.84897328 |
| 5 | MP0003880_abnormal_central_pattern | 2.73934547 |
| 6 | MP0005171_absent_coat_pigmentation | 2.71776702 |
| 7 | MP0003195_calcinosis | 2.63457943 |
| 8 | MP0005248_abnormal_Harderian_gland | 2.60104744 |
| 9 | MP0005377_hearing/vestibular/ear_phenot | 2.53856455 |
| 10 | MP0003878_abnormal_ear_physiology | 2.53856455 |
| 11 | MP0005645_abnormal_hypothalamus_physiol | 2.36380702 |
| 12 | MP0009745_abnormal_behavioral_response | 2.25854397 |
| 13 | MP0006292_abnormal_olfactory_placode | 2.24851142 |
| 14 | MP0002102_abnormal_ear_morphology | 2.17109185 |
| 15 | MP0005410_abnormal_fertilization | 2.17040043 |
| 16 | MP0003283_abnormal_digestive_organ | 2.09307160 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 2.03839121 |
| 18 | MP0002282_abnormal_trachea_morphology | 1.98843719 |
| 19 | MP0008877_abnormal_DNA_methylation | 1.96807155 |
| 20 | MP0001986_abnormal_taste_sensitivity | 1.91968381 |
| 21 | MP0002736_abnormal_nociception_after | 1.91659432 |
| 22 | MP0008875_abnormal_xenobiotic_pharmacok | 1.81532126 |
| 23 | MP0001968_abnormal_touch/_nociception | 1.81483300 |
| 24 | MP0002064_seizures | 1.80901481 |
| 25 | MP0001873_stomach_inflammation | 1.77617307 |
| 26 | MP0005083_abnormal_biliary_tract | 1.75862977 |
| 27 | MP0002249_abnormal_larynx_morphology | 1.75050180 |
| 28 | MP0009046_muscle_twitch | 1.74936676 |
| 29 | MP0005365_abnormal_bile_salt | 1.74748737 |
| 30 | MP0003938_abnormal_ear_development | 1.72013235 |
| 31 | MP0009840_abnormal_foam_cell | 1.67558461 |
| 32 | MP0000566_synostosis | 1.64409848 |
| 33 | MP0002272_abnormal_nervous_system | 1.63499422 |
| 34 | MP0000631_abnormal_neuroendocrine_gland | 1.61077253 |
| 35 | MP0001486_abnormal_startle_reflex | 1.58565547 |
| 36 | MP0005451_abnormal_body_composition | 1.54837030 |
| 37 | MP0000613_abnormal_salivary_gland | 1.54671075 |
| 38 | MP0004133_heterotaxia | 1.51877393 |
| 39 | MP0000534_abnormal_ureter_morphology | 1.51290343 |
| 40 | MP0003119_abnormal_digestive_system | 1.41712767 |
| 41 | MP0005389_reproductive_system_phenotype | 1.40329689 |
| 42 | MP0002638_abnormal_pupillary_reflex | 1.40005197 |
| 43 | MP0003698_abnormal_male_reproductive | 1.35721630 |
| 44 | MP0004859_abnormal_synaptic_plasticity | 1.34998083 |
| 45 | MP0002734_abnormal_mechanical_nocicepti | 1.31400573 |
| 46 | MP0003635_abnormal_synaptic_transmissio | 1.29798052 |
| 47 | MP0002909_abnormal_adrenal_gland | 1.28848397 |
| 48 | MP0004885_abnormal_endolymph | 1.23231131 |
| 49 | MP0001188_hyperpigmentation | 1.21013486 |
| 50 | MP0001542_abnormal_bone_strength | 1.20456438 |
| 51 | MP0009379_abnormal_foot_pigmentation | 1.19544249 |
| 52 | MP0002067_abnormal_sensory_capabilities | 1.19506305 |
| 53 | MP0001485_abnormal_pinna_reflex | 1.18147529 |
| 54 | MP0004147_increased_porphyrin_level | 1.18111959 |
| 55 | MP0002160_abnormal_reproductive_system | 1.15318017 |
| 56 | MP0000026_abnormal_inner_ear | 1.10804285 |
| 57 | MP0003866_abnormal_defecation | 1.09924482 |
| 58 | MP0003718_maternal_effect | 1.07251767 |
| 59 | MP0008789_abnormal_olfactory_epithelium | 1.06069898 |
| 60 | MP0005085_abnormal_gallbladder_physiolo | 1.05992897 |
| 61 | MP0001919_abnormal_reproductive_system | 1.05608394 |
| 62 | MP0004858_abnormal_nervous_system | 1.03136568 |
| 63 | MP0001929_abnormal_gametogenesis | 1.02401942 |
| 64 | MP0003646_muscle_fatigue | 0.99575041 |
| 65 | MP0002932_abnormal_joint_morphology | 0.98068738 |
| 66 | MP0000955_abnormal_spinal_cord | 0.97569472 |
| 67 | MP0001756_abnormal_urination | 0.96302078 |
| 68 | MP0002572_abnormal_emotion/affect_behav | 0.95433603 |
| 69 | MP0005647_abnormal_sex_gland | 0.94582155 |
| 70 | MP0005671_abnormal_response_to | 0.94244811 |
| 71 | MP0002210_abnormal_sex_determination | 0.93819262 |
| 72 | MP0001970_abnormal_pain_threshold | 0.93721212 |
| 73 | MP0002735_abnormal_chemical_nociception | 0.88833505 |
| 74 | MP0003115_abnormal_respiratory_system | 0.86974976 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.86939272 |
| 76 | MP0000639_abnormal_adrenal_gland | 0.86632324 |
| 77 | MP0005187_abnormal_penis_morphology | 0.83906273 |
| 78 | MP0002184_abnormal_innervation | 0.83394221 |
| 79 | MP0001963_abnormal_hearing_physiology | 0.82730698 |
| 80 | MP0000778_abnormal_nervous_system | 0.80699116 |
| 81 | MP0001340_abnormal_eyelid_morphology | 0.80218422 |
| 82 | MP0002752_abnormal_somatic_nervous | 0.79461125 |
| 83 | MP0002089_abnormal_postnatal_growth/wei | 0.77988590 |
| 84 | MP0004924_abnormal_behavior | 0.74211191 |
| 85 | MP0005386_behavior/neurological_phenoty | 0.74211191 |
| 86 | MP0005394_taste/olfaction_phenotype | 0.73937105 |
| 87 | MP0005499_abnormal_olfactory_system | 0.73937105 |
| 88 | MP0002557_abnormal_social/conspecific_i | 0.73552451 |
| 89 | MP0001324_abnormal_eye_pigmentation | 0.73017013 |
| 90 | MP0000163_abnormal_cartilage_morphology | 0.72528462 |
| 91 | MP0000653_abnormal_sex_gland | 0.72213641 |
| 92 | MP0002161_abnormal_fertility/fecundity | 0.72054041 |
| 93 | MP0005503_abnormal_tendon_morphology | 0.71938451 |
| 94 | MP0003315_abnormal_perineum_morphology | 0.70954033 |
| 95 | MP0002063_abnormal_learning/memory/cond | 0.70086735 |
| 96 | MP0000470_abnormal_stomach_morphology | 0.70036985 |
| 97 | MP0003890_abnormal_embryonic-extraembry | 0.69218527 |
| 98 | MP0003943_abnormal_hepatobiliary_system | 0.68821089 |
| 99 | MP0004130_abnormal_muscle_cell | 0.67810171 |
| 100 | MP0002152_abnormal_brain_morphology | 0.67211605 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bilateral sensorineural hearing impairment (HP:0008619) | 7.21471347 |
| 2 | Annular pancreas (HP:0001734) | 5.57466217 |
| 3 | Tubular atrophy (HP:0000092) | 5.05266115 |
| 4 | Birth length less than 3rd percentile (HP:0003561) | 4.46462385 |
| 5 | Tinnitus (HP:0000360) | 4.32690588 |
| 6 | Hyperventilation (HP:0002883) | 4.03315082 |
| 7 | Abnormal pancreas size (HP:0012094) | 3.99998281 |
| 8 | Polydipsia (HP:0001959) | 3.88408113 |
| 9 | Abnormal drinking behavior (HP:0030082) | 3.88408113 |
| 10 | Gaze-evoked nystagmus (HP:0000640) | 3.59978599 |
| 11 | Abnormality of dentin (HP:0010299) | 3.56052852 |
| 12 | Attenuation of retinal blood vessels (HP:0007843) | 3.53482760 |
| 13 | Genetic anticipation (HP:0003743) | 3.39500106 |
| 14 | Tubulointerstitial fibrosis (HP:0005576) | 3.38963703 |
| 15 | Nephronophthisis (HP:0000090) | 3.21888776 |
| 16 | Concave nail (HP:0001598) | 3.11483233 |
| 17 | Hemiparesis (HP:0001269) | 3.11321235 |
| 18 | Abnormality of the renal medulla (HP:0100957) | 3.01934973 |
| 19 | Curly hair (HP:0002212) | 3.01847080 |
| 20 | Anophthalmia (HP:0000528) | 2.97907448 |
| 21 | Inappropriate behavior (HP:0000719) | 2.96613619 |
| 22 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.95452009 |
| 23 | Absent/shortened dynein arms (HP:0200106) | 2.95452009 |
| 24 | Bicornuate uterus (HP:0000813) | 2.93793541 |
| 25 | Clumsiness (HP:0002312) | 2.88441273 |
| 26 | Potter facies (HP:0002009) | 2.87296042 |
| 27 | Facial shape deformation (HP:0011334) | 2.87296042 |
| 28 | Inability to walk (HP:0002540) | 2.87170964 |
| 29 | Polyuria (HP:0000103) | 2.83462205 |
| 30 | Febrile seizures (HP:0002373) | 2.80755221 |
| 31 | Supernumerary spleens (HP:0009799) | 2.79509419 |
| 32 | Pancreatic cysts (HP:0001737) | 2.78874783 |
| 33 | Enlarged penis (HP:0000040) | 2.66298068 |
| 34 | Coronal craniosynostosis (HP:0004440) | 2.63560018 |
| 35 | Breast hypoplasia (HP:0003187) | 2.62754276 |
| 36 | Renovascular hypertension (HP:0100817) | 2.62118559 |
| 37 | Dyskinesia (HP:0100660) | 2.60928095 |
| 38 | Abnormality of the renal cortex (HP:0011035) | 2.57013973 |
| 39 | Abnormality of the dental pulp (HP:0006479) | 2.54879921 |
| 40 | Abnormal urine output (HP:0012590) | 2.53199947 |
| 41 | Enlarged epiphyses (HP:0010580) | 2.52628218 |
| 42 | Small hand (HP:0200055) | 2.51991544 |
| 43 | Protruding tongue (HP:0010808) | 2.46942423 |
| 44 | Decreased central vision (HP:0007663) | 2.46887362 |
| 45 | Patellar aplasia (HP:0006443) | 2.46560932 |
| 46 | Flat occiput (HP:0005469) | 2.42600562 |
| 47 | Chorioretinal atrophy (HP:0000533) | 2.42397265 |
| 48 | Hypophosphatemic rickets (HP:0004912) | 2.39421784 |
| 49 | Large for gestational age (HP:0001520) | 2.35298073 |
| 50 | Tubulointerstitial abnormality (HP:0001969) | 2.28368056 |
| 51 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.28010278 |
| 52 | Abnormality of renal excretion (HP:0011036) | 2.26091921 |
| 53 | Renal duplication (HP:0000075) | 2.24329645 |
| 54 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.23504048 |
| 55 | Nasolacrimal duct obstruction (HP:0000579) | 2.23285882 |
| 56 | Hyperglycinuria (HP:0003108) | 2.22004527 |
| 57 | Molar tooth sign on MRI (HP:0002419) | 2.20537839 |
| 58 | Abnormality of midbrain morphology (HP:0002418) | 2.20537839 |
| 59 | Elfin facies (HP:0004428) | 2.19837095 |
| 60 | Pendular nystagmus (HP:0012043) | 2.18062200 |
| 61 | Generalized myoclonic seizures (HP:0002123) | 2.17085423 |
| 62 | Disinhibition (HP:0000734) | 2.16590287 |
| 63 | Congenital stationary night blindness (HP:0007642) | 2.16050139 |
| 64 | Overriding aorta (HP:0002623) | 2.15034514 |
| 65 | Relative macrocephaly (HP:0004482) | 2.13561974 |
| 66 | Progressive inability to walk (HP:0002505) | 2.08036545 |
| 67 | Congenital sensorineural hearing impairment (HP:0008527) | 2.05747990 |
| 68 | Microretrognathia (HP:0000308) | 2.05040791 |
| 69 | Partial agenesis of the corpus callosum (HP:0001338) | 2.03891193 |
| 70 | Mesangial abnormality (HP:0001966) | 2.01819839 |
| 71 | Progressive cerebellar ataxia (HP:0002073) | 2.01229480 |
| 72 | Acanthocytosis (HP:0001927) | 2.00283641 |
| 73 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.98356201 |
| 74 | Synostosis involving the elbow (HP:0003938) | 1.96685909 |
| 75 | Humeroradial synostosis (HP:0003041) | 1.96685909 |
| 76 | Focal seizures (HP:0007359) | 1.93607952 |
| 77 | Abnormality of alanine metabolism (HP:0010916) | 1.93577580 |
| 78 | Hyperalaninemia (HP:0003348) | 1.93577580 |
| 79 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93577580 |
| 80 | Severe muscular hypotonia (HP:0006829) | 1.93572237 |
| 81 | Bulbous nose (HP:0000414) | 1.91709598 |
| 82 | Azoospermia (HP:0000027) | 1.91553546 |
| 83 | Abnormality of the diencephalon (HP:0010662) | 1.90329305 |
| 84 | Turricephaly (HP:0000262) | 1.87736270 |
| 85 | Status epilepticus (HP:0002133) | 1.84101708 |
| 86 | Broad nasal tip (HP:0000455) | 1.83084496 |
| 87 | Ulnar claw (HP:0001178) | 1.81178509 |
| 88 | Hyperglycinemia (HP:0002154) | 1.78720661 |
| 89 | Abnormality of the lacrimal duct (HP:0011481) | 1.78049496 |
| 90 | Focal motor seizures (HP:0011153) | 1.75908894 |
| 91 | Abnormal lung lobation (HP:0002101) | 1.71539865 |
| 92 | Pancreatic fibrosis (HP:0100732) | 1.70979164 |
| 93 | Osteomalacia (HP:0002749) | 1.70609207 |
| 94 | Atonic seizures (HP:0010819) | 1.69129291 |
| 95 | Hemiplegia (HP:0002301) | 1.69056451 |
| 96 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.68858545 |
| 97 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.68858545 |
| 98 | Posterior embryotoxon (HP:0000627) | 1.66830228 |
| 99 | Macular degeneration (HP:0000608) | 1.66536564 |
| 100 | Drooling (HP:0002307) | 1.66130010 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SIK2 | 5.86360464 |
| 2 | ACVR1B | 5.31251381 |
| 3 | MKNK2 | 4.04984906 |
| 4 | STK39 | 3.71198290 |
| 5 | MAP3K9 | 3.47676992 |
| 6 | BMPR1B | 2.89228657 |
| 7 | WNK4 | 2.78885105 |
| 8 | NTRK2 | 2.51644732 |
| 9 | OXSR1 | 2.47207119 |
| 10 | TYRO3 | 2.32740625 |
| 11 | PLK4 | 2.31906474 |
| 12 | MAP3K6 | 2.13600341 |
| 13 | MAPK15 | 2.05642393 |
| 14 | PTK2B | 1.96897275 |
| 15 | MAP2K7 | 1.95526350 |
| 16 | NEK2 | 1.92743912 |
| 17 | MAP3K4 | 1.84448616 |
| 18 | TLK1 | 1.73472764 |
| 19 | TNIK | 1.72140106 |
| 20 | MKNK1 | 1.70308930 |
| 21 | NTRK3 | 1.58449359 |
| 22 | CAMKK2 | 1.57189060 |
| 23 | INSRR | 1.46432086 |
| 24 | BRSK2 | 1.45171051 |
| 25 | DDR2 | 1.33779344 |
| 26 | ADRBK2 | 1.32752420 |
| 27 | MAP2K1 | 1.26230036 |
| 28 | PIK3CA | 1.25054560 |
| 29 | BCR | 1.23394740 |
| 30 | MAP2K4 | 1.20765474 |
| 31 | RAF1 | 1.14342564 |
| 32 | DAPK2 | 1.12443906 |
| 33 | NEK9 | 1.12211721 |
| 34 | PASK | 1.11529187 |
| 35 | CAMKK1 | 1.10000037 |
| 36 | STK38 | 1.09486109 |
| 37 | TGFBR1 | 1.09086244 |
| 38 | KSR2 | 1.06130261 |
| 39 | GRK1 | 1.03776425 |
| 40 | CDK12 | 0.98615317 |
| 41 | ADRBK1 | 0.93497935 |
| 42 | PIK3CG | 0.93345469 |
| 43 | PINK1 | 0.88258173 |
| 44 | WNK1 | 0.88056319 |
| 45 | CSNK1D | 0.87760029 |
| 46 | PRKCG | 0.81706124 |
| 47 | PRKCQ | 0.78914884 |
| 48 | CAMK1D | 0.77775982 |
| 49 | PNCK | 0.76402020 |
| 50 | MET | 0.70977300 |
| 51 | BMX | 0.67826916 |
| 52 | MAP3K13 | 0.64923473 |
| 53 | MARK3 | 0.63341505 |
| 54 | CDK7 | 0.62278610 |
| 55 | MARK2 | 0.60197997 |
| 56 | NTRK1 | 0.59146262 |
| 57 | RET | 0.58066065 |
| 58 | SIK1 | 0.57280617 |
| 59 | RPS6KA6 | 0.54848614 |
| 60 | MST1R | 0.53381400 |
| 61 | MUSK | 0.52771143 |
| 62 | MARK1 | 0.47596808 |
| 63 | CASK | 0.42840136 |
| 64 | IRAK1 | 0.42561797 |
| 65 | ARAF | 0.42298154 |
| 66 | DYRK1B | 0.41862623 |
| 67 | CAMK1G | 0.40759197 |
| 68 | MATK | 0.34443399 |
| 69 | TRIB3 | 0.34027216 |
| 70 | SIK3 | 0.31627071 |
| 71 | AKT3 | 0.31189379 |
| 72 | PLK1 | 0.30628465 |
| 73 | NUAK1 | 0.30384959 |
| 74 | ERBB2 | 0.30267213 |
| 75 | PTK6 | 0.30105458 |
| 76 | IRAK4 | 0.27225431 |
| 77 | BRSK1 | 0.27176960 |
| 78 | EPHA2 | 0.27151543 |
| 79 | PKN1 | 0.26182317 |
| 80 | EEF2K | 0.23997350 |
| 81 | IKBKB | 0.23829954 |
| 82 | LYN | 0.23577091 |
| 83 | FRK | 0.22995919 |
| 84 | FGFR2 | 0.22958528 |
| 85 | FLT3 | 0.22708952 |
| 86 | MAPK11 | 0.22389573 |
| 87 | CDK1 | 0.21966447 |
| 88 | DYRK1A | 0.20120773 |
| 89 | SGK223 | 0.19425715 |
| 90 | SGK494 | 0.19425715 |
| 91 | PLK2 | 0.17602588 |
| 92 | LATS2 | 0.17327445 |
| 93 | MAPK8 | 0.16857087 |
| 94 | BLK | 0.16664672 |
| 95 | CAMK2A | 0.15716741 |
| 96 | PHKG2 | 0.15205098 |
| 97 | PHKG1 | 0.15205098 |
| 98 | TAOK1 | 0.15106403 |
| 99 | MAPK13 | 0.14820878 |
| 100 | GSK3B | 0.14481279 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 4.09907380 |
| 2 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.57300880 |
| 3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.16527600 |
| 4 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.97215745 |
| 5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.88841289 |
| 6 | Nicotine addiction_Homo sapiens_hsa05033 | 2.55862046 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.45773933 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.42379800 |
| 9 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.41815139 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.37005926 |
| 11 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.35362750 |
| 12 | Taste transduction_Homo sapiens_hsa04742 | 2.25821192 |
| 13 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.11524967 |
| 14 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 2.02574958 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.80763587 |
| 16 | ABC transporters_Homo sapiens_hsa02010 | 1.73248681 |
| 17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.64566558 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.63347428 |
| 19 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.46902860 |
| 20 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.46814429 |
| 21 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.41045873 |
| 22 | Histidine metabolism_Homo sapiens_hsa00340 | 1.40790148 |
| 23 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.39073867 |
| 24 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.37569860 |
| 25 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.32262542 |
| 26 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.31543851 |
| 27 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.24106980 |
| 28 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.23639537 |
| 29 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.16086251 |
| 30 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.13736079 |
| 31 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.09154374 |
| 32 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.08638839 |
| 33 | Cocaine addiction_Homo sapiens_hsa05030 | 1.06686544 |
| 34 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.04222638 |
| 35 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.03162989 |
| 36 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.02504735 |
| 37 | Morphine addiction_Homo sapiens_hsa05032 | 1.02412230 |
| 38 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.97821417 |
| 39 | Long-term depression_Homo sapiens_hsa04730 | 0.96835702 |
| 40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.92454138 |
| 41 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.90937228 |
| 42 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.90821797 |
| 43 | Lysine degradation_Homo sapiens_hsa00310 | 0.86441991 |
| 44 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.86308387 |
| 45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.85650037 |
| 46 | Insulin secretion_Homo sapiens_hsa04911 | 0.84866078 |
| 47 | Bile secretion_Homo sapiens_hsa04976 | 0.82764872 |
| 48 | Circadian entrainment_Homo sapiens_hsa04713 | 0.77664907 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77495742 |
| 50 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.77018140 |
| 51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.73995067 |
| 52 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.72527713 |
| 53 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.70646769 |
| 54 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.70569108 |
| 55 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.70456527 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70375991 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.67285269 |
| 58 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.66964475 |
| 59 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.64118145 |
| 60 | Bladder cancer_Homo sapiens_hsa05219 | 0.63599704 |
| 61 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.63040290 |
| 62 | Salivary secretion_Homo sapiens_hsa04970 | 0.61779601 |
| 63 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.61537096 |
| 64 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.60434003 |
| 65 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.58529437 |
| 66 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.58318270 |
| 67 | Axon guidance_Homo sapiens_hsa04360 | 0.57466394 |
| 68 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.56817906 |
| 69 | Peroxisome_Homo sapiens_hsa04146 | 0.55067088 |
| 70 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.53280338 |
| 71 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.51561656 |
| 72 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.49865316 |
| 73 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.49562202 |
| 74 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.48935910 |
| 75 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48631044 |
| 76 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.46139697 |
| 77 | Melanogenesis_Homo sapiens_hsa04916 | 0.46056657 |
| 78 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.46032702 |
| 79 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.45145963 |
| 80 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.44838162 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44235033 |
| 82 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.44091970 |
| 83 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.43654535 |
| 84 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.42446525 |
| 85 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.42117100 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39771867 |
| 87 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.39362670 |
| 88 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.38908765 |
| 89 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.38389274 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37982608 |
| 91 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.37258964 |
| 92 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36815779 |
| 93 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.36799783 |
| 94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.36080188 |
| 95 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.35503458 |
| 96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.32972675 |
| 97 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.32953417 |
| 98 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.32663644 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.31633629 |
| 100 | RNA polymerase_Homo sapiens_hsa03020 | 0.31056875 |

